Overview
Neha J. Pagidipati, MD, MPH, is an Assistant Professor of Medicine and cardiovascular disease prevention specialist. Since 2011, she has conducted research on cardiometabolic disease prevention, lifestyle modification and weight management. She is currently an NIH K12 scholar in Implementation and Dissemination Science.
Dr. Pagidipati is building the Duke Cardiometabolic Disease Prevention Program, which focuses on behavior change and risk factor management in patients with high risk of cardiovascular and metabolic diseases such as diabetes and obesity. The program’s multi-disciplinary team of cardiologists, endocrinologists, nephrologists, and hepatologists will work together to provide coordinated, team-based care to the most high-risk and complex patients in the health system.
Dr. Pagidipati’s research grants include the COORDINATE-Diabetes Trial, to improve the quality of care for patients with diabetes and cardiovascular disease across the U.S., and QuBBD: Deep Poisson Methods for Biomedical Time-to-Event and Longitudinal Data. She served as a study clinician on the large, longitudinal EXSCEL (Exenatide Study of Cardiovascular Event Lowering) trial. She is currently conducting a nation-wide study of obesity management using real-world data sources, and is a site investigator for the Baseline Health Study in collaboration with Verily Life Sciences. In addition, she is leading a large study within the Duke Health System to study heterogeneity within cardiovascular disease risk and response to weight loss interventions among individuals with obesity.
Dr. Pagidipati graduated from Harvard College and Harvard Medical School. She completed her internal medicine residency at Brigham and Women’s Hospital. During a two-year research fellowship in Global Women’s Health at the Brigham, she obtained an MPH from the Harvard School of Public Health and studied cardiovascular disease prevention in women in India. Dr. Pagidipati completed a four-year cardiology fellowship at the Duke University School of Medicine and served as Chief Research Fellow at the Duke Clinical Research Institute. In 2017, she became a faculty member of the Duke University School of Medicine School.
Current Appointments & Affiliations
Recent Publications
Evaluation of the PREVENT risk assessment tool and visceral adiposity: Insights from the UK Biobank.
Journal Article Prog Cardiovasc Dis · December 9, 2025 BACKGROUND: Visceral adipose tissue (VAT) is a metabolically active fat depot strongly associated with cardiometabolic diseases. Current cardiovascular risk models, including the PREVENT equation, do not incorporate direct measures of visceral fat. This st ... Full text Link to item CiteClinical Update on the Intersection of Lipoprotein(a) and Calcific Valve Disease
Journal Article Current Cardiovascular Risk Reports · December 1, 2025 Purpose of Review: To critically review the literature and summarize the available evidence to better understand the association of Lipoprotein(a) [Lp(a)] and calcific valve disease. Recent Findings: Serum Lp(a) is a causal and independent biomarker associ ... Full text CiteRelationship between interleukin-6, coronary artery calcium and risk of heart failure: Insights from MESA
Journal Article American Journal of Preventive Cardiology · December 1, 2025 Background: This study investigated the joint association of interleukin-6 (IL-6) and coronary artery calcium (CAC) with the risk of heart failure (HF). Methods and Results: Among 6592 participants in the Multi-Ethnic Study of Atherosclerosis (MESA), indiv ... Full text CiteRecent Grants
iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030PCORnet Governance, Collaboration, and Operations to Facilitate PCORnet(R) Studies of National Scope
ResearchCo Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2025 - 2028V-INCLUSION
Clinical TrialPrincipal Investigator · Awarded by Novartis Pharmaceuticals Corporation · 2024 - 2027View All Grants