Neha Pagidipati | Scholars@Duke

Neha Pagidipati
Assistant Professor of Medicine

Neha J. Pagidipati, MD MPH is an Assistant Professor of Medicine and cardiovascular prevention specialist at the DCRI. She served as the Chief Research Fellow at the DCRI between 2016 and 2017 and has been involved with cardiovascular prevention research since 2011. Prior to coming to Duke, she trained at Brigham and Women’s Hospital for internal medicine residency, and then completed a two-year research fellowship in Global Women’s Health at the Brigham. During that time, she also obtained an MPH from the Harvard School of Public Health and studied cardiovascular disease prevention in women in India. Currently, her research focuses on cardiometabolic disease prevention, with particular emphasis on lifestyle modification and weight management. Clinically, she is building the Duke Cardiometabolic Prevention Program, which will focus on behavior change and risk factor management in patients at high risk of cardiovascular and metabolic diseases.

Current Appointments & Affiliations

Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2017
Member of the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2017

Contact Information

Background
Education, Training, & Certifications
- Cardiology Fellowship, Medicine, Duke University School of Medicine 2013 - 2017
- Global Women's Health Fellowship, Brigham and Women's Hospital 2011 - 2013
- M.P.H., Harvard University 2013
- Intership and Residency in Internal Medicine, Brigham and Women's Hospital 2008 - 2011
- M.D., Harvard Medical School 2008
Research
Selected Grants
- Increasing the Quality and Efficiency of Clinical Trials (U18) awarded by Food and Drug Administration 2014 - 2024
- LEADER Trial: Association between weight change and cardiometabolic risk factors in a real-world population of U.S. Adults 2019 - 2022
- QuBBD: Deep Poisson Methods for Biomedical Time-to-Event and Longitudinal Data awarded by National Institutes of Health 2017 - 2020
- Data Characterization of DUHS data for Amgen project 2019 - 2020
- Cardiovascular Risk Profile of LAL Deficiency Patients 2016 - 2020
External Relationships
- Amarin
- Amgen, Inc.
- AstraZeneca
- Baseline Study, LLC
- Boehringer Ingleheim
- Eli Lilly & Co.
- Novo Nordisk
- Sanofi and Regeneron Pharmaceuticals
Publications & Artistic Works
Selected Publications
- Books
  - Gaziano, Thomas A., and Neha Pagidipati. Scaling up chronic disease prevention interventions in lower- and middle-income countries. Vol. 34, 2013. https://doi.org/10.1146/annurev-publhealth-031912-114402.
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- Academic Articles
  - Pagidipati, Neha J., Yinggan Zheng, Jennifer B. Green, Darren K. McGuire, Robert J. Mentz, Svati Shah, Pablo Aschner, et al. “Association of obesity with cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: Insights from TECOS.” Am Heart J 219 (January 2020): 47–57. https://doi.org/10.1016/j.ahj.2019.09.016.
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  - Badjatiya, Anish, Peter Merrill, John B. Buse, Shaun G. Goodman, Brian Katona, Nayyar Iqbal, Neha J. Pagidipati, et al. “Clinical Outcomes in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results From the EXSCEL Trial.” Circ Cardiovasc Interv 12, no. 12 (December 2019): e008018. https://doi.org/10.1161/CIRCINTERVENTIONS.119.008018.
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  - Bhatt, Ankeet S., Nancy Luo, Nicole Solomon, Neha J. Pagidipati, Giuseppe Ambrosio, Jennifer B. Green, Darren K. McGuire, et al. “International variation in characteristics and clinical outcomes of patients with type 2 diabetes and heart failure: Insights from TECOS.” Am Heart J 218 (December 2019): 57–65. https://doi.org/10.1016/j.ahj.2019.08.016.
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  - Goldstein, Benjamin A., Matthew Phelan, Neha J. Pagidipati, and Sarah B. Peskoe. “How and when informative visit processes can bias inference when using electronic health records data for clinical research.” J Am Med Inform Assoc 26, no. 12 (December 1, 2019): 1609–17. https://doi.org/10.1093/jamia/ocz148.
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  - Fudim, Marat, Jennifer White, Neha J. Pagidipati, Yuliya Lokhnygina, Julio Wainstein, Jan Murin, Nayyar Iqbal, et al. “Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.” Circulation 140, no. 20 (November 12, 2019): 1613–22. https://doi.org/10.1161/CIRCULATIONAHA.119.041659.
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  - Gao, Yumin, Eric Peterson, and Neha Pagidipati. “Opportunities for improving use of evidence-based therapy in patients with type 2 diabetes and cardiovascular disease.” Clin Cardiol 42, no. 11 (November 2019): 1063–70. https://doi.org/10.1002/clc.23252.
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  - Farmer, Heather R., Linda A. Wray, Ying Xian, Hanzhang Xu, Neha Pagidipati, Eric D. Peterson, and Matthew E. Dupre. “Racial Differences in Elevated C-Reactive Protein Among US Older Adults.” J Am Geriatr Soc, October 21, 2019. https://doi.org/10.1111/jgs.16187.
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  - Litwin, Sheldon E., Adrian Coles, C Larry Hill, Brooke Alhanti, Neha Pagidipati, Kerry L. Lee, Patricia A. Pellikka, et al. “Discordances between predicted and actual risk in obese patients with suspected cardiac ischaemia.” Heart, October 10, 2019. https://doi.org/10.1136/heartjnl-2018-314503.
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  - Pagidipati, Neha J., and Renato D. Lopes. “New antihyperglycemic medications with cardiovascular protection for patients with diabetes: What do surgeons need to know?” J Thorac Cardiovasc Surg 158, no. 4 (October 2019): 1113–17. https://doi.org/10.1016/j.jtcvs.2019.03.140.
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  - Litwin, Sheldon E., Adrian Coles, Neha Pagidipati, Kerry L. Lee, Patricia A. Pellikka, Daniel B. Mark, James E. Udelson, Udo Hoffmann, Pamela S. Douglas, and Pamela S. PROMISE Investigators. “Effects of obesity on noninvasive test results in patients with suspected cardiac ischemia: Insights from the PROMISE trial.” J Cardiovasc Comput Tomogr 13, no. 4 (July 2019): 211–18. https://doi.org/10.1016/j.jcct.2019.03.010.
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  - Nelson, Adam J., Eric D. Peterson, and Neha J. Pagidipati. “Atherosclerotic cardiovascular disease and heart failure: Determinants of risk and outcomes in patients with diabetes.” Prog Cardiovasc Dis 62, no. 4 (July 2019): 306–14. https://doi.org/10.1016/j.pcad.2019.07.001.
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  - Granger, Christopher B., Adam J. Nelson, and Neha J. Pagidipati. “Risk of Total Events With Icosapent Ethyl: Can We Reduce It?” J Am Coll Cardiol 73, no. 22 (June 11, 2019): 2803–5. https://doi.org/10.1016/j.jacc.2019.03.492.
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  - Goldstein, Benjamin A., Matthew Phelan, Neha J. Pagidipati, Rury R. Holman, Michael J. Pencina, and Elizabeth A. Stuart. “An outcome model approach to transporting a randomized controlled trial results to a target population.” J Am Med Inform Assoc 26, no. 5 (May 1, 2019): 429–37. https://doi.org/10.1093/jamia/ocy188.
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  - Setji, Tracy L., Courtney Page, Neha Pagidipati, and Benjamin A. Goldstein. “DIFFERENCES IN ACHIEVING HBA1C GOALS AMONG PATIENTS SEEN BY ENDOCRINOLOGISTS AND PRIMARY CARE PROVIDERS.” Endocr Pract 25, no. 5 (May 2019): 461–69. https://doi.org/10.4158/EP-2018-0405.
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  - Sharma, Abhinav, Adrian Coles, Nishant K. Sekaran, Neha J. Pagidipati, Michael T. Lu, Daniel B. Mark, Kerry L. Lee, Hussein R. Al-Khalidi, Udo Hoffmann, and Pamela S. Douglas. “Stress Testing Versus CT Angiography in Patients With Diabetes and Suspected Coronary Artery Disease.” J Am Coll Cardiol 73, no. 8 (March 5, 2019): 893–902. https://doi.org/10.1016/j.jacc.2018.11.056.
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  - Christopher, Bridgette A., and Neha J. Pagidipati. “Clinical Updates in Women's Health Care Summary: Evaluation and Management of Lipid Disorders: Primary and Preventive Care Review.” Obstet Gynecol 133, no. 3 (March 2019): 609. https://doi.org/10.1097/AOG.0000000000003139.
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  - Pagidipati, Neha J., Adrian Coles, Kshipra Hemal, Kerry L. Lee, Rowena J. Dolor, Patricia A. Pellikka, Daniel B. Mark, et al. “Sex differences in management and outcomes of patients with stable symptoms suggestive of coronary artery disease: Insights from the PROMISE trial.” Am Heart J 208 (February 2019): 28–36. https://doi.org/10.1016/j.ahj.2018.11.002.
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  - Pagidipati, Neha J., Daniel W. Mudrick, Karen Chiswell, Amanda Brucker, Eric D. Peterson, and Pamela S. Douglas. “Sex differences in long-term outcomes of patients across the spectrum of coronary artery disease.” Am Heart J 206 (December 2018): 51–60. https://doi.org/10.1016/j.ahj.2018.09.014.
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  - Robinson, Jennifer G., Kevin Jon Williams, Samuel Gidding, Jan Borén, Ira Tabas, Edward A. Fisher, Chris Packard, et al. “Eradicating the Burden of Atherosclerotic Cardiovascular Disease by Lowering Apolipoprotein B Lipoproteins Earlier in Life.” J Am Heart Assoc 7, no. 20 (October 16, 2018): e009778. https://doi.org/10.1161/JAHA.118.009778.
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  - Mentz, Robert J., M Angelyn Bethel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, João S. Felício, et al. “Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial.” J Am Heart Assoc 7, no. 19 (October 2, 2018): e009304. https://doi.org/10.1161/JAHA.118.009304.
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  - Pagidipati, Neha J., Anne S. Hellkamp, Puza P. Sharma, Tracy Y. Wang, Gregg C. Fonarow, and Michael Pencina. “High-sensitivity C-reactive protein elevation in patients with prior myocardial infarction in the United States.” Am Heart J 204 (October 2018): 151–55. https://doi.org/10.1016/j.ahj.2018.07.014.
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  - Bhavsar, Nrupen A., Aijing Gao, Matthew Phelan, Neha J. Pagidipati, and Benjamin A. Goldstein. “Value of Neighborhood Socioeconomic Status in Predicting Risk of Outcomes in Studies That Use Electronic Health Record Data.” Jama Netw Open 1, no. 5 (September 7, 2018): e182716. https://doi.org/10.1001/jamanetworkopen.2018.2716.
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  - Pagidipati, Neha J., Robert M. Clare, Robert T. Keenan, Karen Chiswell, Matthew T. Roe, and Connie N. Hess. “Association of Gout With Long-Term Cardiovascular Outcomes Among Patients With Obstructive Coronary Artery Disease.” J Am Heart Assoc 7, no. 16 (August 21, 2018): e009328. https://doi.org/10.1161/JAHA.118.009328.
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  - Prabhakaran, Dorairaj, Kavita Singh, Gregory A. Roth, Amitava Banerjee, Neha J. Pagidipati, and Mark D. Huffman. “Cardiovascular Diseases in India Compared With the United States.” J Am Coll Cardiol 72, no. 1 (July 3, 2018): 79–95. https://doi.org/10.1016/j.jacc.2018.04.042.
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  - Kochar, Ajar, Anita Y. Chen, Puza P. Sharma, Neha J. Pagidipati, Gregg C. Fonarow, Patricia A. Cowper, Matthew T. Roe, Eric D. Peterson, and Tracy Y. Wang. “Long-Term Mortality of Older Patients With Acute Myocardial Infarction Treated in US Clinical Practice.” J Am Heart Assoc 7, no. 13 (June 30, 2018). https://doi.org/10.1161/JAHA.117.007230.
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  - Bethel, M Angelyn, Rishi A. Patel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Robert J. Mentz, Neha J. Pagidipati, et al. “Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis.” Lancet Diabetes Endocrinol 6, no. 2 (February 2018): 105–13. https://doi.org/10.1016/S2213-8587(17)30412-6.
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  - Sharma, Abhinav, Nishant K. Sekaran, Adrian Coles, Neha J. Pagidipati, Udo Hoffmann, Daniel B. Mark, Kerry L. Lee, et al. “Impact of Diabetes Mellitus on the Evaluation of Stable Chest Pain Patients: Insights From the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) Trial.” J Am Heart Assoc 6, no. 11 (October 31, 2017). https://doi.org/10.1161/JAHA.117.007019.
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  - Holman, Rury R., M Angelyn Bethel, Robert J. Mentz, Vivian P. Thompson, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, et al. “Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.” N Engl J Med 377, no. 13 (September 28, 2017): 1228–39. https://doi.org/10.1056/NEJMoa1612917.
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  - Pagidipati, Neha J., Ann Marie Navar, Karen S. Pieper, Jennifer B. Green, M Angelyn Bethel, Paul W. Armstrong, Robert G. Josse, et al. “Secondary Prevention of Cardiovascular Disease in Patients With Type 2 Diabetes Mellitus: International Insights From the TECOS Trial (Trial Evaluating Cardiovascular Outcomes With Sitagliptin).” Circulation 136, no. 13 (September 26, 2017): 1193–1203. https://doi.org/10.1161/CIRCULATIONAHA.117.027252.
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  - Pagidipati, Neha J., Ann Marie Navar, and Michael J. Pencina. “Guideline Recommendations for Statin Therapy-Reply.” Jama 318, no. 10 (September 12, 2017): 964. https://doi.org/10.1001/jama.2017.11379.
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  - Pagidipati, Neha J., Anne Hellkamp, Laine Thomas, Martha Gulati, Eric D. Peterson, and Tracy Y. Wang. “Use of Prescription Smoking Cessation Medications After Myocardial Infarction Among Older Patients in Community Practice.” Jama Cardiol 2, no. 9 (September 1, 2017): 1040–42. https://doi.org/10.1001/jamacardio.2017.2369.
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  - Mentz, Robert J., M Angelyn Bethel, Stephanie Gustavson, Vivian P. Thompson, Neha J. Pagidipati, John B. Buse, Juliana C. Chan, et al. “Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).” Am Heart J 187 (May 2017): 1–9. https://doi.org/10.1016/j.ahj.2017.02.005.
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  - Pagidipati, Neha J., Connie N. Hess, Robert M. Clare, Axel Akerblom, Pierluigi Tricoci, Daniel Wojdyla, Robert T. Keenan, et al. “An examination of the relationship between serum uric acid level, a clinical history of gout, and cardiovascular outcomes among patients with acute coronary syndrome.” Am Heart J 187 (May 2017): 53–61. https://doi.org/10.1016/j.ahj.2017.02.023.
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  - Pagidipati, Neha J., Ann Marie Navar, Hillary Mulder, Allan D. Sniderman, Eric D. Peterson, and Michael J. Pencina. “Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines.” Jama 317, no. 15 (April 18, 2017): 1563–67. https://doi.org/10.1001/jama.2017.3416.
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  - Pagidipati, Neha J., and Christopher B. Granger. “Guideline: The USPSTF recommends low- to moderate-dose statins to prevent CVD in selected adults 40 to 75 years of age.” Ann Intern Med 166, no. 6 (March 21, 2017): JC26. https://doi.org/10.7326/ACPJC-2017-166-6-026.
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  - Pagidipati, Neha J., and Pamela S. Douglas. “The Puzzle of Noninvasive Testing in Women: Filling in the Pieces With the CRESCENT Trial (Calcium Imaging and Selective CT Angiography in Comparison to Functional Testing for Suspected Coronary Artery Disease).” Circ Cardiovasc Imaging 10, no. 2 (February 2017). https://doi.org/10.1161/CIRCIMAGING.117.006085.
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  - Pagidipati, Neha J., and Eric D. Peterson. “Acute coronary syndromes in women and men.” Nat Rev Cardiol 13, no. 8 (August 2016): 471–80. https://doi.org/10.1038/nrcardio.2016.89.
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  - Pagidipati, Neha J., Kshipra Hemal, Adrian Coles, Daniel B. Mark, Rowena J. Dolor, Patricia A. Pellikka, Udo Hoffmann, et al. “Sex Differences in Functional and CT Angiography Testing in Patients With Suspected Coronary Artery Disease.” J Am Coll Cardiol 67, no. 22 (June 7, 2016): 2607–16. https://doi.org/10.1016/j.jacc.2016.03.523.
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  - Pagidipati, Neha J., Michael Pencina, and Allan D. Sniderman. “The Enigma of Glucose and Lipid Metabolism.” Jama Cardiol 1, no. 2 (May 1, 2016): 145–46. https://doi.org/10.1001/jamacardio.2016.0183.
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  - Hemal, Kshipra, Neha J. Pagidipati, Adrian Coles, Rowena J. Dolor, Daniel B. Mark, Patricia A. Pellikka, Udo Hoffmann, et al. “Sex Differences in Demographics, Risk Factors, Presentation, and Noninvasive Testing in Stable Outpatients With Suspected Coronary Artery Disease: Insights From the PROMISE Trial.” Jacc Cardiovasc Imaging 9, no. 4 (April 2016): 337–46. https://doi.org/10.1016/j.jcmg.2016.02.001.
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  - Pagidipati, Neha Jadeja, and Thomas A. Gaziano. “Estimating deaths from cardiovascular disease: a review of global methodologies of mortality measurement.” Circulation 127, no. 6 (February 12, 2013): 749–56. https://doi.org/10.1161/CIRCULATIONAHA.112.128413.
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  - Pagidipati, Neha J., Mark D. Huffman, Panniyammakal Jeemon, Rajeev Gupta, Prakash Negi, Thannikot M. Jaison, Satyavan Sharma, et al. “Association between gender, process of care measures, and outcomes in ACS in India: results from the detection and management of coronary heart disease (DEMAT) registry.” Plos One 8, no. 4 (2013): e62061. https://doi.org/10.1371/journal.pone.0062061.
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  - Pagidipati, Neha, Keith L. Obstein, Rachel Rucker-Schmidt, Robert D. Odze, and Christopher C. Thompson. “Acute hepatitis due to epstein-barr virus in an immunocompetent patient.” Dig Dis Sci 55, no. 4 (April 2010): 1182–85. https://doi.org/10.1007/s10620-009-0835-z.
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- Book Sections
  - Gaziano, T. A., and N. J. Pagidipati. “Global cardiovascular therapy.” In Cardiovascular Therapeutics: A Companion to Braunwald’s Heart Disease: Fourth Edition, 75–82, 2012. https://doi.org/10.1016/B978-1-4557-0101-8.00006-0.
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Education, Training, & Certifications

Selected Grants

External Relationships

Selected Publications

Books

Academic Articles

Book Sections