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Neil J. Freedman

Professor of Medicine
Medicine, Cardiology
Duke Box 102150, Durham, NC 27710
447 Clin & Res Labs, Box 102150 Duke University Medical Ctr, Durham, NC 27710

Selected Grants


IND-enabling studies for an RNA therapeutic to treat atherosclerosis

ResearchCo Investigator · Awarded by Department of Defense · 2024 - 2028

Mechanisms by which Small Nucleolar RNAs Exacerbate Atherosclerosis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2026

Immune-endothelial cell dysfunction in radiation-induced atherosclerosis

ResearchCollaborating Investigator · Awarded by American Heart Association · 2024 - 2025

Anti-Atherogenic Mechanisms of Drebrin

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2024

Regulation of Vascular Inflammatory Signaling by the Deubiquitinase USP20

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2024

Multidisciplinary Heart and Vascular Diseases

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 1975 - 2023

Mechanistic studies of Mas receptor activation and its role in aortic aneurysm formation

ResearchCollaborator · Awarded by National Institutes of Health · 2017 - 2021

Role of Debrin in Vascular Smooth Muscle Transdifferentiation

ResearchCollaborating Investigator · Awarded by American Heart Association · 2019 - 2019

Role of Drebrin in Atherosclerosis

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2019

Anti-atherogenic Mechanisms of the Dual Rho-GEF Kalirin

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2018

Regulation of B-arrestin2's pro-atherogenic activity by the deubiquitinase USP20

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2014 - 2018

Role of Drebrin in Vascular Smooth Muscle Remodeling

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2018

Desensitization of Vascular Receptor Tyrosine Kinases

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2012

Mechanisms of Arterial Wall-Mediated Atherogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2009

Aging, Atherosclerosis, and the Arterial Wall

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2009

Inflammation in Vein Graft Disease: A Genetic Approach

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2004 - 2006

TNF-Inhibitor Gene Therapy for Neointimal Hyperplasia

ResearchCo Investigator · Awarded by National Institutes of Health · 2001 - 2005

Receptor Kinase Gene Therapy for Neointimal Hyperplasia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1999 - 2004

Same

ResearchPrincipal Investigator · Awarded by Department of Health and Human Services · 1997 - 2001

Receptor Kinase Gene Therapy For Neointimal Hyperplasia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Receptor Desensitization In The Cardiovascular System

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1999

External Relationships


  • Crowe & Harris, LLP
  • Faiella & Gulden, P.A.
  • Stockman O¿Connor Connors

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.