Overview
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2022 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Director, DCI Biostatistics
·
2020 - Present
Biostatistics & Bioinformatics,
Basic Science Departments
Member of the Duke Cancer Institute
·
1997 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Safety and feasibility of talimogene laherparepvec in peritoneal surface malignancies: Results from the TEMPO trial.
Journal Article Mol Ther Oncol · March 19, 2026 Peritoneal surface malignancies (PSMs) remain a therapeutic challenge, particularly in patients with unresectable disease who cannot benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. The Talimogene Laherparepvec for the Trea ... Full text Link to item CitePhase II Trial of Interleukin-12 Followed by Interferon Alfa-2b in Patients with Metastatic Malignant Melanoma: Results from CALGB 500001 (Alliance).
Journal Article Cancer Immunol Res · March 4, 2026 The ability of IL12 to stimulate production of IFNγ suggested it might improve the efficacy of low-dose IFNα. In this phase II trial, patients with metastatic malignant melanoma were administered recombinant human (rh) IL12 followed by IFNα2b. Primary endp ... Full text Link to item CiteToxicity of Ablative Radiation Therapy in the Management of Patients with Child-Pugh B/C Liver Function and Unresectable Hepatocellular Carcinoma (HCC).
Journal Article Cancers (Basel) · February 19, 2026 BACKGROUND/OBJECTIVES: Hypofractionated ablative radiation is an increasingly popular option for patients with hepatocellular carcinoma (HCC). However, concern remains about the risk for radiation-induced liver toxicity in patients with decompensated liver ... Full text Link to item CiteRecent Grants
Serum pro-N-cadherin as an early biomarker of radiation-induced heart disease
ResearchStatistician · Awarded by National Institutes of Health · 2025 - 2030Project 2: Inflammation and Submucosal Glands During Esophageal Injury and Repair
ResearchCo Investigator · Awarded by Case Western Reserve University · 2023 - 2028Biomarker validation for intraductal papillary mucinous neoplasms of the pancreas
ResearchCo Investigator · Awarded by National Cancer Institute · 2018 - 2028View All Grants
Education
Yale University ·
1984
Ph.D.