Scholars@Duke
Obinna Ogochukwu Adibe

Obinna Ogochukwu Adibe

Consulting Associate in the Department of Surgery
Surgery, Pediatric General Surgery
obinna.adibe@duke.edu
301 East Wendover Ave, Suite 311, Greensboro, NC 27401

Selected Publications

Surgical Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Lead to Severe Growth Failure in Infants.

Journal Article Ann Surg · September 1, 2024 OBJECTIVE: We aimed to determine the incidence of growth failure in infants with necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) and whether initial laparotomy versus peritoneal drainage (PD) impacted the likelihood of growth fa ... Full text Link to item Cite

Cervical seatbelt sign is not associated with blunt cerebrovascular injury in children: A review of the national trauma databank.

Journal Article Am J Surg · July 2019 BACKGROUND: Blunt cerebrovascular injury (BCVI) is a rare consequence of blunt trauma. There appears to be benefit to an aggressive approach to screening for BCVI due to catastrophic sequelae of unrecognized injury. However, screening for BCVI carries exte ... Full text Link to item Cite

Racial/ethnic differences in necrotizing enterocolitis incidence and outcomes in premature very low birth weight infants.

Journal Article J Perinatol · October 2018 BACKGROUND: As advances in neonatal intensive care increase the survival of extremely premature infants, the at-risk population for necrotizing enterocolitis (NEC) continues to rise. Although racial health disparities in preterm births have been well docum ... Full text Link to item Cite

A multi-institution analysis of predictors of timing of inguinal hernia repair among premature infants.

Journal Article J Pediatr Surg · April 2018 PURPOSE: Inguinal hernias are common in premature infants, but there is substantial variation with regards to timing of repair. We sought to quantify and explain this variation. METHODS: Cohort study of infants <34weeks gestation diagnosed with an inguinal ... Full text Link to item Cite

Comparing oncologic outcomes after minimally invasive and open surgery for pediatric neuroblastoma and Wilms tumor.

Journal Article Pediatr Blood Cancer · January 2018 BACKGROUND: Minimally invasive surgery (MIS) has been widely adopted for common operations in pediatric surgery; however, its role in childhood tumors is limited by concerns about oncologic outcomes. We compared open and MIS approaches for pediatric neurob ... Full text Link to item Cite

Are esophagocrural sutures needed during laparoscopic fundoplication: A prospective randomized trial

Journal Article Journal of Pediatric Surgery · January 1, 2018 Purpose: Historically, fundoplication has been performed with extensive dissection of the esophageal attachments to the diaphragm. Previously, we conducted a randomized trial demonstrating that minimal esophageal dissection and mobilization reduce the rate ... Full text Cite

Outcomes following elective resection of congenital pulmonary airway malformations are equivalent after 3 months of age and a weight of 5 kg.

Journal Article J Pediatr Surg · October 9, 2017 PURPOSE: Resection of congenital pulmonary airway malformations (CPAMs) is often performed to reduce the risk of recurrent infection and malignant transformation. However, there is substantial variation in the timing of resection. This study was performed ... Full text Link to item Cite

Diagnostic evaluation of ovarian torsion: An analysis of pediatric patients using the Nationwide Emergency Department Sample.

Journal Article Am J Surg · April 2017 BACKGROUND: Ultrasonography (US) is the diagnostic modality of choice during work-up for ovarian torsion, although computed tomography (CT) may be used. We examined the utilization of CT in girls with ovarian torsion, and determined which patients are most ... Full text Link to item Cite

Vascular Complications in Pediatric Port Removal.

Journal Article Am Surg · April 1, 2017 Link to item Cite

Vascular Complications in Pediatric Port Removal.

Journal Article Am Surg · April 1, 2017 Link to item Cite

Vascular Complications in Pediatric Port Removal.

Journal Article Am Surg · April 1, 2017 Link to item Cite

Predictors of nodal metastasis in pediatric differentiated thyroid cancer.

Journal Article J Pediatr Surg · January 2017 BACKGROUND/PURPOSE: There are limited data identifying risk factors for nodal metastasis in children with differentiated thyroid cancer. METHODS: The 1998-2011 Surveillance, Epidemiology, and End Results Program database was queried for patients ≤18years o ... Full text Link to item Cite

Current use and outcomes of helicopter transport in pediatric trauma: a review of 18,291 transports.

Journal Article J Pediatr Surg · January 2017 PURPOSE: The role of helicopter emergency medical services (HEMS) in pediatric trauma remains controversial. We examined its use in pediatric trauma and its effectiveness in children with moderate/severe injuries. METHODS: All blunt/penetrating trauma pati ... Full text Link to item Cite

Influence of weight at enterostomy reversal on surgical outcomes in infants after emergent neonatal stoma creation.

Journal Article J Pediatr Surg · January 2017 PURPOSE: Neonates after emergent enterostomy creation frequently require reversal at low weight because of complications including cholestasis, dehydration, dumping, failure to thrive, and failure to achieve enteral independence. We investigated whether st ... Full text Link to item Cite

Extracorporeal life support use in pediatric trauma: a review of the National Trauma Data Bank.

Journal Article J Pediatr Surg · January 2017 PURPOSE: As the role of extracorporeal life support (ECLS) continues to evolve in the adult and pediatric populations, smaller studies and case reports have described successful use of ECLS in specific groups of pediatric trauma patients. To further define ... Full text Link to item Cite

Postoperative Venous Thromboembolism in Children Is Increased in Setting of Cancer or Infection

Conference Blood · December 2, 2016 AbstractBackground: Venous thromboembolism (VTE) is an uncommon but clinically significant postoperative complication in children. Incidence of VTE in pediatric patients ranges from 34-58 per 10,000 hospital ... Full text Cite

Gastrostomy tube placement in infants with congenital diaphragmatic hernia: Frequency, predictors, and growth outcomes.

Journal Article Early Hum Dev · December 2016 BACKGROUND: Gastrostomy tube (G-tube) placement is a common intervention for newborns with severe feeding difficulties. Infants with congenital diaphragmatic hernia (CDH) are at high risk for feeding problems. Prevalence of G-tube placement and consequent ... Full text Link to item Cite

Real-time ultrasonography for placement of central venous catheters in children: A multi-institutional study.

Conference Surgery · December 2016 BACKGROUND: Recommendations for the use of real-time ultrasonography for placement of central venous catheters in children are based on studies involving adults treated by nonsurgeons. Our purpose was to determine the frequency of use of real-time ultrason ... Full text Link to item Cite

Real-time ultrasonography for placement of central venous catheters in children: A multi-institutional study.

Conference Surgery · December 2016 BACKGROUND: Recommendations for the use of real-time ultrasonography for placement of central venous catheters in children are based on studies involving adults treated by nonsurgeons. Our purpose was to determine the frequency of use of real-time ultrason ... Full text Link to item Cite

Comparative effectiveness of treatment strategies for severe splenic trauma in the pediatric population.

Journal Article Am J Surg · October 2016 Featured Publication BACKGROUND: Splenic angioembolization (SAE) is increasingly used in the management of splenic injuries in adults, although its value in pediatric trauma is unclear. We sought to assess outcomes related to splenectomy vs SAE. METHODS: The National Trauma Da ... Full text Link to item Cite

Laparoscopy Is Safe in Infants and Neonates with Congenital Heart Disease: A National Study of 3684 Patients.

Journal Article J Laparoendosc Adv Surg Tech A · October 2016 PURPOSE: Concerns have been raised about the use of laparoscopic surgery (LS) in infants with congenital heart disease (CHD) due to their unique physiology. Prior studies on the safety and effectiveness of laparoscopy in children with CHD are limited in sc ... Full text Link to item Cite

Management of blunt pancreatic trauma in children: Review of the National Trauma Data Bank.

Journal Article J Pediatr Surg · September 2016 PURPOSE: This study aims to examine the current management strategies and outcomes after blunt pancreatic trauma in children using a national patient registry. METHODS: Using the National Trauma Data Bank (NTDB) from 2007-2011, we identified all patients ≤ ... Full text Link to item Cite

Understanding parental refusal of permission for child participation in surgical prospective trials.

Journal Article Pediatr Surg Int · May 2016 PURPOSE: The success of prospective randomized trials relies on voluntary participation, which has been perceived as a barrier for successful trials in children who rely on parental permission. We sought to identify the reasons parents decline child partic ... Full text Link to item Cite

Necrotizing enterocolitis and the use of loop diuretics in very low birth weight neonates.

Journal Article Am J Surg · April 2016 Featured Publication BACKGROUND: Necrotizing enterocolitis (NEC) is a gastrointestinal disease of premature, very low birth weight neonates resulting in sepsis and death. Loop diuretics are widely used in neonates as a treatment for pulmonary fluid retention. An association be ... Full text Link to item Cite

Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB).

Journal Article J Pediatr Surg · January 2016 PURPOSE: Adrenocortical carcinoma (ACC) is a rare tumor in children with important distinctions from the adult disease. We reviewed the National Cancer Data Base (NCDB) to determine factors associated with long-term survival. METHODS: The NCDB was queried ... Full text Link to item Cite

Use of patient registries and administrative datasets for the study of pediatric cancer.

Journal Article Pediatr Blood Cancer · September 2015 Analysis of data from large administrative databases and patient registries is increasingly being used to study childhood cancer care, although the value of these data sources remains unclear to many clinicians. Interpretation of large databases requires a ... Full text Link to item Cite

Saline vs Tissue Plasminogen Activator Irrigations after Drain Placement for Appendicitis-Associated Abscess: A Prospective Randomized Trial.

Journal Article J Am Coll Surg · August 2015 Featured Publication BACKGROUND: Emerging data suggest instillation of tissue plasminogen activator (tPA) is safe and potentially efficacious in the treatment of intra-abdominal abscess. To date, prospective comparative data are lacking in children. Therefore, we conducted a r ... Full text Link to item Cite

Predictors of gastrostomy placement in children with inherited metabolic diseases treated by umbilical cord blood transplantation.

Journal Article J Pediatr Surg · July 2015 Featured Publication BACKGROUND/PURPOSE: Children with inherited metabolic diseases (IMDs) undergoing umbilical cord blood transplantation (UCBT) who are at risk for post-transplant failure to thrive may benefit from pretransplant gastrostomy tube (GT) placement. Here we sough ... Full text Link to item Cite

Laparoscopic excision of an extra-biliary gallbladder duplication cyst in a 9-month-old infant.

Journal Article Afr J Paediatr Surg · 2015 Duplication of the gallbladder is a rare congenital anomaly of the biliary system. We herein present a case of a 9-month-old full-term female with a prenatally identified gallbladder duplication cyst managed via laparoscopic excision. ... Full text Link to item Cite

Operative vs nonoperative management for blunt pancreatic transection in children: multi-institutional outcomes.

Journal Article J Am Coll Surg · February 2014 BACKGROUND: The management of traumatic pancreatic transection remains controversial. STUDY DESIGN: A multi-institutional review from 1995 to 2012 was conducted comparing operative with nonoperative management for grades II and III blunt pancreatic injurie ... Full text Link to item Cite

Protocol versus ad libitum feeds after laparoscopic pyloromyotomy: a prospective randomized trial.

Journal Article J Pediatr Surg · January 2014 Featured Publication BACKGROUND: We conducted a prospective, randomized trial comparing protocol to ad libitum (ad lib) feeding after laparoscopic pyloromyotomy. METHODS: Infants undergoing laparoscopic pyloromyotomy were randomized to protocol versus ad lib feeding strategies ... Full text Link to item Cite

Laparoscopic antireflux surgery in infants with single ventricle physiology: a review.

Journal Article J Laparoendosc Adv Surg Tech A · August 2013 Laparoscopic fundoplication and gastrostomy tube placement have grown in popularity within the pediatric population for treatment of gastroesophageal reflux disease and failure to thrive, respectively. One population that has an increased need for gastric ... Full text Link to item Cite

Single incision versus standard 4-port laparoscopic cholecystectomy: a prospective randomized trial.

Journal Article J Pediatr Surg · January 2013 BACKGROUND: Laparoscopy through a single umbilical incision is an emerging technique supported by case series, but prospective comparative data are lacking. Therefore, we conducted a prospective, randomized trial comparing single site umbilical laparoscopi ... Full text Link to item Cite

Laparoscopic repair of incarcerated congenital diaphragmatic hernias presenting beyond the newborn period.

Journal Article J Laparoendosc Adv Surg Tech A · December 2012 PURPOSE/BACKGROUND: Congenital diaphragmatic hernias (CDHs) diagnosed outside of the newborn period are an uncommon occurrence in developed countries. Incarceration of viscera presenting as bowel obstruction is a rare clinical scenario with only a few case ... Full text Link to item Cite

Crohn's Disease

Chapter · December 1, 2012 Full text Cite

Irrigation versus suction alone during laparoscopic appendectomy for perforated appendicitis: a prospective randomized trial.

Journal Article Ann Surg · October 2012 Featured Publication BACKGROUND: The efficacy of irrigating the peritoneal cavity during appendectomy for perforated appendicitis has been debated extensively. To date, prospective comparative data are lacking. Therefore, we conducted a prospective, randomized trial comparing ... Full text Link to item Cite

Distribution of feeding styles after pyloromyotomy among pediatric surgical training programs in North America.

Journal Article Eur J Pediatr Surg · October 2012 INTRODUCTION: The feeding regimen employed after pyloromyotomy for pyloric stenosis continues to be a topic of debate and has yet to be evaluated in a prospective, randomized trial. To understand the spectrum of current feeding schedules being utilized in ... Full text Link to item Cite

Crohn's Disease

Chapter · February 14, 2012 Full text Cite

Colon cancer with microsatellite instability in a 13-year-old Hispanic male.

Journal Article J Clin Oncol · February 10, 2012 Featured Publication Full text Link to item Cite

The use of high-frequency oscillating ventilation to facilitate stability during neonatal thoracoscopic operations.

Journal Article J Laparoendosc Adv Surg Tech A · November 2011 BACKGROUND: Thoracoscopy has become a surgical option for the repair of esophageal atresia (EA) and congenital diaphragmatic hernia (CDH). Insufflation of carbon dioxide combined with one lung ventilation creates an anesthetic challenge to control acidosis ... Full text Link to item Cite

Single incision versus standard 3-port laparoscopic appendectomy: a prospective randomized trial.

Journal Article Ann Surg · October 2011 Featured Publication BACKGROUND: Laparoscopic appendectomy through a single umbilical incision is an emerging approach supported by several case series. However, to date, prospective comparative data are lacking. Therefore, we conducted a prospective, randomized trial comparin ... Full text Link to item Cite

Severity of appendicitis correlates with the pediatric appendicitis score.

Journal Article Pediatr Surg Int · June 2011 PURPOSE: The pediatric appendicitis score (PAS) has been used as a diagnostic tool for the assessment of acute abdominal pain. Our institution has utilized this scoring system as part of a clinical pathway for acute appendicitis. We sought to discover if t ... Full text Link to item Cite

An evidence-based clinical protocol for diagnosis of acute appendicitis decreased the use of computed tomography in children.

Journal Article J Pediatr Surg · January 2011 Featured Publication PURPOSE: The increased use of computed tomography (CT) to diagnose appendicitis in children has led to a concern for the possibility of increased CT-related cancer morbidity. We designed a clinical protocol for the diagnosis and treatment of appendicitis i ... Full text Link to item Cite

Appendectomy using single-incision pediatric endosurgery for acute and perforated appendicitis.

Journal Article Surg Endosc · December 2010 BACKGROUND: Single-incision pediatric endosurgical (SIPES) appendectomy has been reported in few pediatric surgical centers. We have adopted the technique recently and have offered it to all patients in whom appendectomy was indicated. The purpose of this ... Full text Link to item Cite

Single-incision laparoscopic pyloromyotomy: initial experience.

Journal Article Surg Endosc · July 2010 BACKGROUND: Laparoscopic pyloromyotomy has become the standard treatment for hypertrophic pyloric stenosis. Single-incision laparoscopic surgery is an emerging operative approach that utilizes the umbilical scar to hide the surgical incision. OBJECTIVE: To ... Full text Link to item Cite

Laparoscopic-assisted repair of femoral hernias in children.

Journal Article J Laparoendosc Adv Surg Tech A · October 2009 BACKGROUND: Femoral hernias in children are rare, difficult to diagnose, and require a different treatment approach than the standard indirect inguinal hernia repair. Most femoral hernias in children are still repaired by using a conventional McVay techniq ... Full text Link to item Cite

Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen.

Journal Article Am J Surg · February 2008 BACKGROUND: Although treatment for nonperforated acute appendicitis is usually straightforward, the optimal treatment of patients with perforated appendicitis remains controversial. METHODS: Our institution performed a 2.5-year retrospective review of outc ... Full text Link to item Cite

Ad libitum feeds after laparoscopic pyloromyotomy: a retrospective comparison with a standardized feeding regimen in 227 infants.

Journal Article J Laparoendosc Adv Surg Tech A · April 2007 PURPOSE: The best feeding regimen after pyloromyotomy for hypertrophic pyloric stenosis continues to be a topic of some debate. Postoperative emesis and length of hospital stay are principal concerns. We compared the outcome of infants after laparoscopic p ... Full text Link to item Cite

Evidence for an immune barrier after in utero hematopoietic-cell transplantation.

Journal Article Blood · February 1, 2007 The competence of the immune system of the developing fetus to act as a barrier to in utero hematopoietic-cell transplantation (IUHCT) has been a source of debate. Until now, comparisons of allogeneic and congenic engraftment have been inconclusive due to ... Full text Link to item Cite

CD26 inhibition enhances allogeneic donor-cell homing and engraftment after in utero hematopoietic-cell transplantation.

Journal Article Blood · December 15, 2006 In utero hematopoietic-cell transplantation (IUHCT) can induce donor-specific tolerance to facilitate postnatal transplantation. Induction of tolerance requires a threshold level of mixed hematopoietic chimerism. CD26 is a peptidase whose inhibition increa ... Full text Link to item Cite

Evidence for an Adaptive Immune Barrier after in Utero Hematopoietic Cell Transplantation.

Conference Blood · November 16, 2006 AbstractIn utero hematopoietic cell transplantation (IUHCT) is a nonmyeloablative approach that takes advantage of normal immunologic development to achieve donor specific tolerance. Despite the many potenti ... Full text Cite

Comparison of outcomes after laparoscopic and open pyloromyotomy at a high-volume pediatric teaching hospital.

Journal Article J Pediatr Surg · October 2006 BACKGROUND/PURPOSE: Laparoscopic pyloromyotomy (LP) is used widely for treatment of hypertrophic pyloric stenosis. We examined the results of pyloromyotomy at a high-volume pediatric teaching hospital to compare outcomes of laparoscopic and open pyloromyot ... Full text Link to item Cite

Gunshot wounds: bullet caliber is increasing, 1998-2003.

Journal Article Am Surg · April 2004 In 1999, Caruso reported data from the level 1 trauma center in Newark, New Jersey, documenting "...an ominous trend toward the use of larger caliber firearms in accidents, homicides and suicides." Those data were derived from measurements of bullets remov ... Link to item Cite

GUNSHOT WOUNDS: CALIBER IS INCREASING, 1998 - 2003.

Conference Journal of Investigative Medicine · January 2004 Full text Cite