Scholars@Duke
Steven Arthur Olson

Steven Arthur Olson

Goldner Jones Distinguished Professor of Orthopaedic Surgery
Orthopaedic Surgery
DUMC Box 104002, Durham, NC 27710
311 Trent Drive, Durham, NC 27710

Selected Publications

The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal Article Anesth Analg · January 1, 2025 BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of ... Full text Link to item Cite

Elevated body mass index and obesity are associated with pain-associated psychological distress in patients with hip pain.

Journal Article Arch Orthop Trauma Surg · December 12, 2024 INTRODUCTION: Little research has investigated the relationship between musculoskeletal pain and body mass index (BMI) in the context of pain-associated psychological distress. This study aims to determine if independent associations exist between BMI, obe ... Full text Link to item Cite

Mode of injury and level of synovitis alter inflammatory chondrocyte gene expression and associated pathways.

Journal Article Sci Rep · November 21, 2024 Although various joint injuries result in post-traumatic osteoarthritis (PTOA), differences in chondrocyte response to specific injuries, such as blunt compression or fracture, are unclear. Furthermore, the role of underlying joint inflammation, or synovit ... Full text Link to item Cite

Decision-making in borderline hip dysplasia and concomitant femoracetabular impingement syndrome: using a discrete choice experiment to explore patient preferences.

Journal Article J Hip Preserv Surg · July 2024 Decision-making regarding surgical treatment of patients showing radiographic evidence of femoroacetabular impingement syndrome (FAIS) in the setting of borderline hip dysplasia (BHD) remains a challenge as there is no consensus on treatment in current lit ... Full text Link to item Cite

Racial Disparities Exist in 90-Day Unplanned Return to the Emergency Department Following Orthopaedic Trauma Surgery.

Journal Article J Orthop Trauma · July 1, 2024 OBJECTIVES: Racial disparities in healthcare outcomes exist, including in orthopaedic trauma care. The aim of this study was to determine the impact of race, social deprivation, and payor status on 90-day emergency department (ED) revisits among orthopaedi ... Full text Link to item Cite

Does psychological distress predict risk of orthopaedic surgery and postoperative opioid prescribing in patients with hip pain? A retrospective study.

Journal Article BMC Musculoskelet Disord · April 20, 2024 BACKGROUND: Clinicians and public health professionals have allocated resources to curb opioid over-prescription and address psychological needs among patients with musculoskeletal pain. However, associations between psychological distress, risk of surgery ... Full text Link to item Cite

Pain-Associated Psychological Distress Is of High Prevalence in Patients With Hip Pain: Characterizing Psychological Distress and Phenotypes.

Journal Article Arthrosc Sports Med Rehabil · February 2024 PURPOSE: To identify common pain-related psychological factors among patients seeking care for athletic hip pain, as well as characterize psychological distress phenotypes and compare hip-specific quality-of-life measures across those phenotypes. METHODS: ... Full text Link to item Cite

Posttraumatic osteoarthritis: From basic science to clinical implications

Journal Article OTA International · May 1, 2023 Posttraumatic osteoarthritis (PTOA) is a subset of osteoarthritis that occurs after joint injury and is associated with degradation of articular cartilage and subchondral bone. As compared with primary osteoarthritis, PTOA occurs in a time window initiated ... Full text Cite

Is perioperative COVID-19 really associated with worse surgical outcomes? A nationwide COVIDSurg propensity-matched analysis.

Journal Article J Trauma Acute Care Surg · April 1, 2023 BACKGROUND: Patients undergoing surgery with perioperative COVID-19 are suggested to have worse outcomes, but whether this is COVID-related or due to selection bias remains unclear. We aimed to compare the postoperative outcomes of patients with and withou ... Full text Link to item Cite

Critical Risk Factors for Opioid Demand after Pelvic and Acetabular Fracture Surgery.

Journal Article J Surg Orthop Adv · 2023 The characteristics that contribute to opioid demand in pelvic and acetabular fracture surgery are not well understood. We hypothesize that fracture pattern and psychiatric comorbidities will be associated with increased opioid demand. This study evaluated ... Link to item Cite

Who, if anyone, may benefit from a total hip arthroplasty after a displaced femoral neck fracture?

Journal Article Bone & Joint Open · August 1, 2022 Aims The aim of this study was to explore the functional results in a fitter subgroup of participants in the Hip Fracture Evaluation with Alternatives of Total Hip Arthroplasty versus Hemiarthroplasty (HEALTH) tri ... Full text Cite

Arthrodesis of the Pubic Symphysis With Compression Plating and Femoral Strut Allograft for Pubic Instability and Osteitis Pubis: A Novel Surgical Technique

Journal Article Techniques in Orthopaedics · June 18, 2022 Introduction: Osteitis pubis and pubic instability represent an uncommon, yet a potentially debilitating problem for patients. While many cases are amendable to conservative measures, the few recalcitrant cases present a difficult challenge for surgical ma ... Full text Cite

Combination of Lidocaine and IL-1Ra Is Effective at Reducing Degradation of Porcine Cartilage Explants.

Journal Article Am J Sports Med · June 2022 BACKGROUND: Posttraumatic inflammation after joint injury, ranging from sprains to articular fracture, contributes to the development of arthritis, and the administration of interleukin 1 (IL-1) receptor antagonist (IL-1Ra) is a potential intervention to m ... Full text Link to item Cite

High Prevalence of Sleep Disturbance Is Associated with Femoroacetabular Impingement Syndrome.

Journal Article Arthrosc Sports Med Rehabil · April 2022 PURPOSE: The purpose of this study was to identify an association between Patient-Reported Outcomes Measurement Information System (PROMIS) sleep scores and other PROMIS domains in patients with femoroacetabular impingement syndrome (FAIS). METHODS: Patien ... Full text Open Access Link to item Cite

Intra-Articular Synovial Fluid With Hematoma After Ankle Fracture Promotes Cartilage Damage In Vitro Partially Attenuated by Anti-Inflammatory Agents.

Journal Article Foot Ankle Int · March 2022 BACKGROUND: Intra-articular ankle fracture (IAF) causes posttraumatic osteoarthritis (PTOA), but the exact mechanism is unknown. Proinflammatory mediators have been shown to be present in the synovial fluid fracture hematoma (SFFH) but have not been linked ... Full text Link to item Cite

Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA

Journal Article Annals of Surgery · February 2022 Objective:To report the 30-day outcomes of patients with perioperative SARS-CoV-2 infection undergoing surgery in the USA.Background:Uncertainty regar ... Full text Cite

Surgical Technique: Post-less, Single-Table Combined Periacetabular Osteotomy and Arthroscopy

Chapter · January 1, 2022 The young adult hip has garnered much attention over the past decade, as evidenced by this text’s formative second edition. That focus has been divided among open and arthroscopic surgical techniques. The Ganz periacetabular osteotomy (PAO) has been the go ... Full text Cite

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score.

Journal Article Br J Surg · November 11, 2021 To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in s ... Full text Open Access Link to item Cite

Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection.

Journal Article BJS Open · November 9, 2021 There is little evidence around the potentially protective role of previous Bacillus Calmette-Guerin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 vaccination. Prior BCG vaccination did not protect SARS-CoV-2 infect ... Full text Open Access Link to item Cite

Initial displacement of the intra-articular surface after articular fracture correlates with PTA in C57BL/6 mice but not "superhealer" MRL/MpJ mice.

Journal Article J Orthop Res · September 2021 Posttraumatic arthritis (PTA) occurs commonly after articular fracture and may arise, in part, from joint surface incongruity after injury. MRL/MpJ (MRL) "super-healer" mice are protected from PTA compared to C57BL/6 (B6) mice following articular fracture. ... Full text Open Access Link to item Cite

Degenerative joint changes following intra-articular fracture are more severe in mice with T cell deficiency.

Journal Article J Orthop Res · August 2021 The inflammatory response to joint injury, specifically intra-articular fracture, has been implicated in posttraumatic arthritis development. However, the role of T cells in regulating the development of posttraumatic arthritis is unclear. We hypothesized ... Full text Link to item Cite

Can PROMIS measures be used to create subgroups for patients seeking orthopaedic care?

Journal Article Bone Jt Open · July 2021 AIMS: Patient-reported outcome measures have become an important part of routine care. The aim of this study was to determine if Patient-Reported Outcomes Measurement Information System (PROMIS) measures can be used to create patient subgroups for individu ... Full text Open Access Link to item Cite

Immune cell profiling in the joint following human and murine articular fracture.

Journal Article Osteoarthritis Cartilage · June 2021 OBJECTIVE: Human and in vivo animal research implicates inflammation following articular fracture as contributing to post-traumatic arthritis. However, relevant immune cell subsets present following injury are currently undefined. Immunophenotyping human a ... Full text Link to item Cite

Risk Factors Associated With Infection in Open Fractures of the Upper and Lower Extremities.

Journal Article J Am Acad Orthop Surg Glob Res Rev · December 8, 2020 INTRODUCTION: Open fractures are associated with a high risk of infection. The prevention of infection is the single most important goal, influencing perioperative care of patients with open fractures. Using data from 2,500 participants with open fracture ... Full text Link to item Cite

The Impact of Early Epidural Discontinuation on Pain, Opioid Usage, and Length of Stay After Periacetabular Osteotomy.

Journal Article J Bone Joint Surg Am · November 4, 2020 BACKGROUND: Periacetabular osteotomy (PAO) is the standard of care for treatment of symptomatic acetabular dysplasia. Patients undergoing PAO for acetabular dysplasia have postoperative pain that can be managed with epidural analgesia. The purpose of this ... Full text Link to item Cite

The Association of Prescriber Awareness of Opioid Consumption Trends with Postoperative Opioid Prescription Volume in Hip Arthroscopy: Prescriber Awareness of Opioid Consumption.

Journal Article Arthrosc Sports Med Rehabil · October 2020 PURPOSE: To evaluate the impact of prescriber knowledge of 6-week postoperative opioid usage trends on postoperative opioid prescribing in hip arthroscopy for femoroacetabular impingement syndrome. METHODS: Two groups of patients undergoing hip arthroscopy ... Full text Link to item Cite

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.

Journal Article Lancet · July 4, 2020 BACKGROUND: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmo ... Full text Link to item Cite

Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee.

Journal Article Osteoarthritis Cartilage · May 2020 OBJECTIVE: Acute synovial inflammation following joint trauma is associated with posttraumatic arthritis. Synovial macrophages have been implicated in degenerative changes. In this study, we sought to elucidate the role of intra-articular macrophages in th ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Operative Treatment of Pediatric Pelvic and Acetabulum Fractures.

Journal Article J Orthop Trauma · December 2019 Pediatric pelvic fractures are rare and differ from adults in etiology, fracture type, and associated injuries. They are observed in multitrauma patients, with severe associated injuries. Treatment of these children in specialized hospitals is likely to pr ... Full text Link to item Cite

Single Table Concomitant Post-Less Hip Arthroscopy Combined with Periacetabular Osteotomy for Hip Dysplasia.

Journal Article Arthrosc Tech · December 2019 It has been well established that both arthroscopic and open hip preservation techniques can result in improved patient outcomes and interrupt the natural history of hip disease. Traditionally, hip arthroscopy has been used to address central and periphera ... Full text Link to item Cite

Pathogenesis of Posttraumatic Osteoarthritis of the Ankle.

Journal Article Orthop Clin North Am · October 2019 Ankle osteoarthritis affects a significant portion of the global adult population. Unlike other joints, arthritis of the ankle often develops as a response to traumatic injury (intra-articular fracture) of the ankle joints. The full mechanism leading to po ... Full text Link to item Cite

Understanding Articular Cartilage Injury and Potential Treatments.

Journal Article J Orthop Trauma · June 2019 The goals of all orthopaedic surgeons treating articular cartilage injuries have been anatomic reduction and stable fixation of the articular cartilage surface with restoration of limb alignment and/or reestablishment of the joint stability, all while mini ... Full text Link to item Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

Relationship Between PROMIS Computer Adaptive Tests and Legacy Hip Measures Among Patients Presenting to a Tertiary Care Hip Preservation Center.

Journal Article Am J Sports Med · March 2019 BACKGROUND: Legacy hip outcome measures may be burdensome to patients and sometimes yield floor or ceiling effects. Patient-Reported Outcomes Measurement Information System (PROMIS) computer adaptive tests (CATs) allow for low-burden data capture and limit ... Full text Link to item Cite

Evaluation of the safety and efficacy of a new hemostatic powder using a quantitative surface bleeding severity scale.

Journal Article J Card Surg · January 2019 AIMS OF THE STUDY: The safety and efficacy of a hemostatic powder (HP) versus a control agent, absorbable gelatin sponge and thrombin (G + T), were assessed, using a validated, quantitative bleeding severity scale. METHODS: Subjects were randomized to rece ... Full text Link to item Cite

High Body Mass Index is Related to Increased Perioperative Complications After Periacetabular Osteotomy.

Journal Article Am J Orthop (Belle Mead NJ) · August 2018 The purpose of this study is to determine the relationship of body mass index (BMI), age, smoking status, and other comorbid conditions to the rate and type of complications occurring in the perioperative period following periacetabular osteotomy. A retros ... Full text Link to item Cite

Wound Surface Area as a Risk Factor for Flap Complications among Patients with Open Fractures.

Journal Article Plast Reconstr Surg · July 2018 BACKGROUND: Soft-tissue complications often dictate the success of limb salvage and the overall outcome of open fractures. Based on prior work at the R Adams Cowley Shock Trauma Center, the authors hypothesize that wounds larger than 200 cm are associated ... Full text Link to item Cite

Prospective, Observational Study of Opioid Use After Hip Arthroscopy for Femoroacetabular Impingement Syndrome.

Journal Article Arthroscopy · May 2018 PURPOSE: To provide estimates of postoperative opioid use after hip arthroscopy for femoroacetabular impingement (FAI) syndrome and to identify risk factors for increased postoperative opioid use. METHODS: All patients aged at least 18 years who were under ... Full text Link to item Cite

Are large clinical trials in orthopaedic trauma justified?

Journal Article BMC Musculoskelet Disord · April 20, 2018 BACKGROUND: The objective of this analysis is to evaluate the necessity of large clinical trials using FLOW trial data. METHODS: The FLOW pilot study and definitive trial were factorial trials evaluating the effect of different irrigation solutions and pre ... Full text Link to item Cite

CXCL10 is upregulated in synovium and cartilage following articular fracture.

Journal Article J Orthop Res · April 2018 The objective of this study was to investigate the expression of the chemokine CXCL10 and its role in joint tissues following articular fracture. We hypothesized that CXCL10 is upregulated following articular fracture and contributes to cartilage degradati ... Full text Open Access Link to item Cite

Advanced Imaging Adds Little Value in the Diagnosis of Femoroacetabular Impingement Syndrome.

Journal Article J Bone Joint Surg Am · December 20, 2017 BACKGROUND: Femoroacetabular impingement (FAI) syndrome is an increasingly recognized source of hip pain and disability in young active adults. In order to confirm the diagnosis, providers often supplement physical examination maneuvers and radiographs wit ... Full text Link to item Cite

Early recovery after hip arthroscopy for femoroacetabular impingement syndrome: a prospective, observational study.

Journal Article J Hip Preserv Surg · December 2017 The early post-operative course after hip arthroscopy for femoroacetabular impingement syndrome has not been thoroughly characterized or correlated to factors that may influence recovery. The aim of this study was to report on early pain, function and atti ... Full text Open Access Link to item Cite

Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures.

Journal Article Foot Ankle Int · May 2017 BACKGROUND: Post-traumatic osteoarthritis (PTOA) is responsible for the majority of cases of ankle arthritis. While acute and end-stage intra-articular inflammation has previously been described, the state of the joint between fracture healing and end-stag ... Full text Link to item Cite

Lipid profile of human synovial fluid following intra-articular ankle fracture.

Journal Article J Orthop Res · March 2017 This study characterizes the metabolic profile of synovial fluid after intra-articular ankle fracture with an emphasis on changes in the lipid profile. Bilateral ankle synovial fluid from 19 patients with unilateral intra-articular ankle fracture was submi ... Full text Link to item Cite

Functional outcome measures in a surgical model of hip osteoarthritis in dogs.

Journal Article J Exp Orthop · December 2016 BACKGROUND: The hip is one of the most common sites of osteoarthritis in the body, second only to the knee in prevalence. However, current animal models of hip osteoarthritis have not been assessed using many of the functional outcome measures used in orth ... Full text Open Access Link to item Cite

Hot Topics in Biomechanics: Hip Fracture Fixation.

Journal Article J Orthop Trauma · December 2015 Geriatric hip fractures continue to increase in frequency as the population ages, and intertrochanteric femur fractures are a significant part of these injuries. Plate fixation for intertrochanteric fractures of the proximal femur has been in use for many ... Full text Link to item Cite

Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture.

Journal Article Foot Ankle Int · November 2015 BACKGROUND: Posttraumatic osteoarthritis (PTOA) can occur after intra-articular fracture despite anatomic fracture reduction. It has been hypothesized that an early inflammatory response after intra-articular injury could lead to irreversible cartilage dam ... Full text Link to item Cite

Non-invasive mouse models of post-traumatic osteoarthritis.

Journal Article Osteoarthritis Cartilage · October 2015 Animal models of osteoarthritis (OA) are essential tools for investigating the development of the disease on a more rapid timeline than human OA. Mice are particularly useful due to the plethora of genetically modified or inbred mouse strains available. Th ... Full text Link to item Cite

Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.

Journal Article J Orthop Res · September 2015 An estimated 12% of patients seeking surgical intervention for symptomatic arthritis have an etiology of post-traumatic arthritis (PTA). The onset of PTA is rapid in the setting of articular fracture (AF). The investigation began with development of a muri ... Full text Link to item Cite

Two admission pathways for elderly patients with hip fracture: Clinical outcomes at a single institution

Journal Article Current Orthopaedic Practice · July 9, 2015 Background: The incidence of hip fractures increases exponentially after the age of 65, and that number will continue to rise over the coming decades as the population ages. In an attempt to provide better patient care for elderly patients with hip fractur ... Full text Cite

Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines.

Journal Article Arthritis Rheumatol · May 2015 OBJECTIVE: The inflammatory response following an articular fracture is thought to play a role in the development of posttraumatic arthritis (PTA) but has not been well characterized. The objective of this study was to characterize the acute inflammatory r ... Full text Link to item Cite

Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.

Journal Article Eur Cell Mater · January 31, 2015 Post-traumatic arthritis (PTA) is a rapidly progressive form of arthritis that develops due to joint injury, including articular fracture. Current treatments are limited to surgical restoration and stabilization of the joint; however, evidence suggests tha ... Full text Link to item Cite

Whole joint models of articular injury and articular fracture

Chapter · January 1, 2015 A variety of whole joint models have been reported to study the effects of articular injury. This chapter reviews whole joint injury models in both human cadavers and animal models. These injury models include articular loading without fracture, fracture ( ... Full text Cite

Unanswered questions and future directions in post-traumatic arthritis

Chapter · January 1, 2015 While there is increasing interest in PTA as a disease process, the area is relatively unstudied. In many cases joint injuries are managed mainly by orthopedic surgeons. Orthopedic surgeons have used surgical management as the primary (and often only) form ... Full text Cite

Arthritis that develops after joint injury: Is it post-traumatic arthritis or post-traumatic osteoarthritis?

Chapter · January 1, 2015 Arthritis that develops after joint injury, or post-traumatic arthritis (PTA), is increasingly recognized as an important contributor to the overall burden of arthritis. PTA is in many ways ideal for the study of development of arthritis. PTA has known joi ... Full text Cite

Stem cell therapies for post-traumatic arthritis

Chapter · January 1, 2015 Post-traumatic arthritis is a progressive and debilitating joint disease that commonly occurs following joint trauma, such as ligament injury, meniscal tear, or intra-articular fracture. However, there are few therapeutic approaches currently available tha ... Full text Cite

Preface

Journal Article Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management · 2015 Full text Cite

Osteoarthritis: From Palliation to Prevention: AOA Critical Issues.

Journal Article J Bone Joint Surg Am · August 6, 2014 Osteoarthritis is a leading cause of disability. The traditional focus on late-stage osteoarthritis has not yielded effective disease-modifying treatments. Consequently, current clinical care focuses on palliation until joint replacement is indicated. A sy ... Full text Link to item Cite

Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.

Journal Article Arthritis Res Ther · June 25, 2014 INTRODUCTION: Post-traumatic arthritis (PTA) is a progressive, degenerative response to joint injury, such as articular fracture. The pro-inflammatory cytokines, interleukin 1(IL-1) and tumor necrosis factor alpha (TNF-α), are acutely elevated following jo ... Full text Open Access Link to item Cite

The role of cytokines in posttraumatic arthritis.

Journal Article J Am Acad Orthop Surg · January 2014 The development of arthritis after joint injury is commonly known as posttraumatic arthritis (PTA). The inciting traumatic event may range from cartilage contusion and bone bruise combined with meniscus or ligament tear, to intra-articular fracture. End-st ... Full text Link to item Cite

Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers.

Journal Article J Orthop Res · August 2013 Post-traumatic arthritis (PTA) frequently develops after intra-articular fracture of weight bearing joints. Loss of cartilage viability and post-injury inflammation have both been implicated as possible contributing factors to PTA progression. To further i ... Full text Link to item Cite

Understanding how orthopaedic surgery practices generate value for healthcare systems.

Journal Article Clin Orthop Relat Res · June 2013 BACKGROUND: Orthopaedic surgery practices can provide substantial value to healthcare systems. Increasingly, healthcare administrators are speaking of the need for alignment between physicians and healthcare systems. However, physicians often do not unders ... Full text Link to item Cite

Healthcare technology: physician collaboration in reducing the surgical cost.

Journal Article Clin Orthop Relat Res · June 2013 BACKGROUND: The increasing cost of providing health care is a national concern. Healthcare spending related to providing hospital care is one of the primary drivers of healthcare spending in the United States. Adoption of advanced medical technologies acco ... Full text Link to item Cite

Prolonged local delivery of IL-1Ra prevents post-traumatic arthritis in mice

Journal Article Osteoarthritis and Cartilage · April 2013 Full text Cite

Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.

Journal Article Arthritis Rheum · March 2013 OBJECTIVE: To examine the relationship between inflammation and posttraumatic arthritis (PTA) in a murine intraarticular fracture model. METHODS: Male C57BL/6 and MRL/MpJ "superhealer" mice received tibial plateau fractures using a previously established m ... Full text Link to item Cite

Orthopedic traumatology: An evidence-based approach

Book · January 1, 2013 © Springer Science+Business Media New York 2013.Physicians are under increasing pressure to provide quality health care in the most cost-effective way possible. The escalating costs of orthopedic care are driving the need to base clinical decision making o ... Full text Cite

Pelvic ring injury I

Chapter · January 1, 2013 © Springer Science+Business Media New York 2013.DP is a 43-year-old man who complains of right pelvic pain after being a restrained passenger in a motor vehicle accident. He is transferred to the emergency department via EMS. On presentation, he demonstrat ... Full text Cite

Proceedings from the research colloquium on post-traumatic arthritis

Journal Article Duke Orthopaedic Journal · 2013 Cite

Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis.

Journal Article Cell Transplant · 2013 Joint injury dramatically enhances the onset of osteoarthritis (OA) and is responsible for an estimated 12% of OA. Posttraumatic arthritis (PTA) is especially common after intra-articular fracture, and no disease-modifying therapies are currently available ... Full text Link to item Cite

Predictors of length of hospital stay in elderly hip fracture patients.

Journal Article J Surg Orthop Adv · 2013 The purpose of this study was to assess the relationship between prefracture characteristics and length of stay (LOS) at the authors' institution. Three hundred eighty-nine consecutive elderly hip fracture patients' preoperative characteristics, comorbidit ... Full text Link to item Cite

Designing a biomechanics investigation: choosing the right model.

Journal Article J Orthop Trauma · December 2012 Physical testing is commonly performed to answer important biomechanical questions in the treatment of patients with fractures and other orthopaedic conditions. However, a variety of mistakes that are made in performing such investigations can severely lim ... Full text Link to item Cite

Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice.

Journal Article Arthritis Rheum · October 2012 OBJECTIVE: Obesity and joint injury are primary risk factors for osteoarthritis (OA) that involve potential alterations in the biomechanical and inflammatory environments of the joint. Posttraumatic arthritis is a frequent long-term complication of intraar ... Full text Link to item Cite

Combined Arthroscopic and Mini-Open Treatment of CAM-Type Femoroacetabular Impingement

Journal Article The Duke Orthopaedic Journal · June 2012 ABSTRACTPurposeOsteochondroplasty of the femoral head-neck junction can improve hip pain and function in patients with femoroacetabular impingement. We report our initial series of patient ... Full text Cite

Review of Two Approaches for the Care of Elderly Hip Fracture Patients

Journal Article Journal of Trauma and Treatment · 2012 Cite

Computer-assisted reduction method for periprosthetic distal femur fracture.

Journal Article J Surg Orthop Adv · 2012 The purpose of this case report is to describe a novel use of computer assistance in identifying and restoring the mechanical axis in the treatment of a periprosthetic distal femur fracture in a 76-year-old female patient with a total knee arthroplasty. ... Full text Link to item Cite

Direct anterior approach for total hip arthroplasty using the fracture table.

Journal Article Curr Rev Musculoskelet Med · September 2011 Featured Publication Total hip arthroplasty is a successful procedure for treatment of painful hip arthritides. A large volume of literature is devoted to the patient outcomes and complication profiles of the commonly used surgical approaches to help refine the technique, enha ... Full text Link to item Cite

Association between timing of zoledronic acid infusion and hip fracture healing.

Journal Article Osteoporos Int · August 2011 UNLABELLED: Patients in the Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly (HORIZON) Recurrent Fracture Trial were assessed for evidence of delayed hip fracture healing. No association was observed between zoledronic acid (ZOL) and ... Full text Link to item Cite

Development of a collaborative program to provide extracorporeal membrane oxygenation for adults with refractory hypoxemia within the framework of a pandemic.

Journal Article Pediatr Crit Care Med · July 2011 OBJECTIVE: We report the process used to rapidly develop a collaborative adult respiratory extracorporeal membrane oxygenation program as a response to caring for young adult patients with refractory hypoxemia in the setting of the pH1N1 pandemic. DESIGN: ... Full text Link to item Cite

Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee.

Journal Article Osteoarthritis Cartilage · July 2011 Featured Publication OBJECTIVE: Post-traumatic arthritis is a frequent cause of disability and occurs most commonly and predictably after articular fracture. The objective of this investigation was to examine the effect of fracture severity on acute joint pathology in a novel ... Full text Link to item Cite

The Bernese Periacetabular Osteotomy: A Review of Surgical Technique

Journal Article The Duke Orthopaedic Journal · June 2011 ABSTRACTThe Bernese periacetabular osteotomy (PAO) is a powerful technique in the treatment of hip dysplasia and related conditions of the hip. This technique is performed through a single anterior surgical approach. There ... Full text Cite

Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention.

Journal Article J Orthop Res · June 2011 Even with current treatments of acute joint injuries, more than 40% of people who suffer significant ligament or meniscus tears, or articular surface injuries, will develop osteoarthritis (OA). Correspondingly, 12% or more of all patients with lower extrem ... Full text Link to item Cite

Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture.

Journal Article J Orthop Res · April 2011 Featured Publication Posttraumatic arthritis commonly develops following articular fracture. The objective of this study was to develop a closed joint model of transarticular impact with and without creation of an articular fracture that maintains the physiologic environment d ... Full text Link to item Cite

Applied biomechanics in articular injuries: perspectives in the basic investigation of articular injuries and clinical application.

Journal Article Instr Course Lect · 2011 Featured Publication Joint injury is an important cause of arthritis. Although the treatment of injury, in general, has been widely studied, the contribution of injury to the development of posttraumatic arthritis is still a relatively understudied area. One of the most perple ... Link to item Cite

Timing of definitive fixation of severe tibial plateau fractures with compartment syndrome does not have an effect on the rate of infection.

Journal Article J Trauma · December 2010 BACKGROUND: Tibial plateau fractures with associated compartment syndrome are severe injuries with elevated infection rates. The objective of this article was to analyze whether there is an association between infection and the timing of definitive fractur ... Full text Link to item Cite

Editorial comment

Journal Article Journal of Trauma - Injury, Infection and Critical Care · October 1, 2010 Full text Cite

Resident duty-hour reform associated with increased morbidity following hip fracture.

Journal Article J Bone Joint Surg Am · September 2009 BACKGROUND: The Accreditation Council for Graduate Medical Education implemented resident duty-hour reform for orthopaedic resident surgeons in the United States on July 1, 2003. This study sought to determine whether the change in duty-hour regulations wa ... Full text Link to item Cite

Timing of fracture fixation in multitrauma patients: the role of early total care and damage control surgery.

Journal Article J Am Acad Orthop Surg · September 2009 The optimal timing of surgical stabilization of fractures in the multitrauma patient is controversial. There are advantages to early definitive surgery for most patients. Early temporary fixation using external fixators, followed by definitive fixation (ie ... Full text Link to item Cite

Soft-tissue defects and exposed hardware: a review of indications for soft-tissue reconstruction and hardware preservation.

Journal Article Plast Reconstr Surg · April 2009 BACKGROUND: Traditionally, management of exposed hardware has included irrigation and dĂ©bridement, intravenous antibiotics, and likely removal of the hardware. Increasingly, the goal of wound closure without hardware removal using plastic surgical techniqu ... Full text Link to item Cite

A retrospective review of high-energy femoral neck-shaft fractures.

Journal Article J Orthop Trauma · April 2009 OBJECTIVES: To determine the incidence of femoral neck fractures with high-energy shaft fractures and to determine whether there was a correlation of neck fractures with antegrade or retrograde intramedullary nailing. We also evaluated the timing of diagno ... Full text Link to item Cite

Hip fracture outcomes: does surgeon or hospital volume really matter?

Journal Article J Trauma · March 2009 BACKGROUND: Current data on the association between surgeon and hospital volumes and patient outcomes after hip fracture surgery is inconclusive. We hypothesized that surgeons and hospitals with higher caseloads of hip fracture care have better outcomes as ... Full text Link to item Cite

Observer variability in assessing articular surface displacement in acetabular fractures using a standardized measurement technique.

Journal Article J Surg Orthop Adv · 2009 The objective of this study was to determine the inter- and intraobserver reliability of plain films as compared with CT scans in quantitatively measuring articular displacement in acetabular fractures utilizing a standardized measurement technique. Three ... Link to item Cite

Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice.

Journal Article Osteoarthritis Cartilage · December 2008 OBJECTIVE: We evaluated three methodologies--a calcium sodium alginate compound (CSAC), polyacrylate beads (PABs), and Whatman paper recovery (WPR)--for the ability to recover synovial fluid (SF) from mouse knees in a manner that facilitated biochemical ma ... Full text Link to item Cite

Single-leg-stance (flamingo) radiographs to assess pelvic instability: how much motion is normal?

Journal Article J Bone Joint Surg Am · October 2008 Featured Publication BACKGROUND: Chronic pelvic instability is a relatively uncommon cause of pelvic and low-back pain. Patients present with feelings of instability and mechanical symptoms. Static radiographs are often inadequate to detect abnormal relative motion between the ... Full text Link to item Cite

Two-year outcomes in primary THA in obese male veterans administration medical center patients.

Journal Article Rheumatol Int · September 2008 The objective of this study was to examine the influence of obesity on the rate of infection, dislocation, and overall complications in a group of male patients undergoing primary total hip arthroplasty (THA). The study involved a retrospective review of t ... Full text Link to item Cite

Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.

Journal Article Arthritis Rheum · March 2008 Featured Publication OBJECTIVE: Posttraumatic arthritis is a frequent long-term complication of intraarticular fractures. A model of a closed intraarticular fracture in C57BL/6 mice that progresses to posttraumatic arthritis has been developed. The MRL/MpJ mouse has shown uniq ... Full text Link to item Cite

Augmentation of posterior wall acetabular fracture fixation using calcium-phosphate cement: a biomechanical analysis.

Journal Article J Orthop Trauma · October 2007 OBJECTIVE: This study investigates if the use of calcium phosphate cement as an adjunct to internal fixation for posterior wall acetabular fracture will result in acute restoration of joint loading parameters to the intact condition. METHODS: Ten fresh-fro ... Full text Link to item Cite

Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma.

Journal Article J Bone Joint Surg Br · October 2007 Post-traumatic arthritis is a frequent consequence of articular fracture. The mechanisms leading to its development after such injuries have not been clearly delineated. A potential contributing factor is decreased viability of the articular chondrocytes. ... Full text Link to item Cite

Medium-term results of the Bernese periacetabular osteotomy in the treatment of symptomatic developmental dysplasia of the hip.

Journal Article J Bone Joint Surg Br · June 2007 Featured Publication We studied the medium-term outcome of the Bernese periacetabular osteotomy in 52 patients (58 hips) with symptomatic developmental dysplasia of the hip and a mean age of 37.6 years (13 to 48). The operations were performed between 1993 and 2005 by the seni ... Full text Link to item Cite

Current management of high-energy tibial plateau fractures

Journal Article Current Orthopaedics · June 1, 2007 High-energy tibial plateau fractures present a therapeutic challenge to the orthopaedic trauma surgeon, both in terms of the osseous injury as well as the concomitant soft-tissue insult. Surgical treatment has evolved to address these fractures in a more b ... Full text Cite

Joint degeneration following closed intraarticular fracture in the mouse knee: a model of posttraumatic arthritis.

Journal Article J Orthop Res · May 2007 Posttraumatic arthritis is one of the most frequent causes of disability following joint trauma. The objective of this study was to develop a model of a closed articular fracture in the mouse knee joint to quantify the temporal sequence of joint degenerati ... Full text Link to item Cite

Fluoroscopic imaging guides of the posterior pelvis pertaining to iliosacral screw placement.

Journal Article J Trauma · February 2007 Featured Publication BACKGROUND: This study correlates anatomic landmarks with radiographic densities and radiolucencies of the posterior pelvis, which assists in percutaneous iliosacral screw placement. METHODS: Radio-opaque markers were placed on selected surfaces of cadaver ... Full text Link to item Cite

Commentary

Journal Article The Journal of Bone & Joint Surgery · February 2007 Full text Cite

A survey of orthopaedic traumatologists concerning the use of bone growth stimulators.

Journal Article J Surg Orthop Adv · 2007 The purpose of the study was to determine the attitudes of members of the Orthopaedic Trauma Association (OTA) concerning the use and efficacy of bone growth stimulators. A questionnaire regarding bone growth stimulators was sent to the active members of t ... Link to item Cite

Does knee position at the time of tourniquet inflation affect knee range of motion?

Journal Article J Surg Orthop Adv · 2007 Pneumatic tourniquets about the thigh are commonly employed in lower extremity orthopaedic surgery to maintain a bloodless operative field. The purpose of this study was to determine whether the position of the knee at the time of tourniquet inflation has ... Link to item Cite

T.F. Roush, S.A. Olson, R. Pietrobon, L. Braga, and J.R. Urbaniak reply [4]

Journal Article Journal of Bone and Joint Surgery · January 1, 2007 Cite

Comprehensive morphologic evaluation of the hip in patients with symptomatic labral tear.

Journal Article Clin Orthop Relat Res · December 2006 Featured Publication A torn acetabular labrum is a well-documented source of hip pain, but the mechanism of injury is debated because the relationship between the bone morphology and labral tears is poorly understood. We compared hips with and without labral abnormalities to d ... Full text Link to item Cite

Validation of a Spanish version of the Short Musculoskeletal Function Assessment Questionnaire (SMFA).

Journal Article J Orthop Trauma · October 2006 OBJECTIVES: The purpose of this study was to develop a linguistically appropriate, culturally adapted, and appropriately validated Spanish version of the SMFA (SMFA-Mex). DESIGN: Validation of a survey-based outcome instrument. SETTING: Busy state hospital ... Full text Link to item Cite

Influence of acetabular coverage on hip survival after free vascularized fibular grafting for femoral head osteonecrosis.

Journal Article J Bone Joint Surg Am · October 2006 BACKGROUND: Osteonecrosis of the femoral head frequently results in collapse of the head and subsequent arthrosis of the joint. Surgical treatment has been based entirely on the evaluation of the femoral side of the hip joint, with little consideration giv ... Full text Link to item Cite

In response

Journal Article Journal of Orthopaedic Trauma · October 1, 2006 Full text Cite

Surgical treatment of non-unions: A case for internal fixation.

Journal Article Injury · August 2006 Non-unions present a particular challenge to the fracture surgeon and are frequently underestimated by the average practitioner. Although the use of ring fixation techniques is gaining in popularity, there remains a definite role for the use of bone grafti ... Full text Link to item Cite

Acetabular and Pelvic Fractures

Book · January 1, 2006 The text is structured into four chapters: topics that are common to both evaluation and treatment of pelvic ring and acetabualr fractures, information specific to classification, treatment, and outcomes of pelvic ring injures, information ... ... Cite

The development of posttraumatic arthritis after articular fracture.

Journal Article J Orthop Trauma · 2006 Featured Publication Posttraumatic arthritis (PTA) is one of the most frequent causes of disability after trauma involving weight-bearing joints and is estimated to be responsible for approximately 10% of the 21 million Americans who have osteoarthritis. Despite a number of si ... Full text Link to item Cite

Acute compartment syndrome in lower extremity musculoskeletal trauma.

Journal Article J Am Acad Orthop Surg · November 2005 Acute compartment syndrome is a potentially devastating condition in which the pressure within an osseofascial compartment rises to a level that decreases the perfusion gradient across tissue capillary beds, leading to cellular anoxia, muscle ischemia, and ... Full text Link to item Cite

Pelvic ring injuries: Fixation of the posterior pelvic ring

Journal Article European Journal of Trauma · November 1, 2005 Pelvic ring injuries are increasingly common in motor vehicle trauma. The minority of pelvic ring injuries require operative fixation. This paper outlines the basic techniques for posterior pelvic ring reduction and fixation including relevant biomechanics ... Full text Cite

CT-based acetabular fracture classification.

Journal Article AJR Am J Roentgenol · July 2005 Full text Link to item Cite

Cross-cultural adaptation and validation of the Brazilian Portuguese version of the short musculoskeletal function assessment questionnaire: the SMFA-BR.

Journal Article J Bone Joint Surg Am · April 2005 BACKGROUND: This study was designed to translate, culturally adapt, and validate a Brazilian Portuguese version of the Short Musculoskeletal Function Assessment Questionnaire (SMFA-BR). METHODS: The SMFA was translated from English into Brazilian Portugues ... Full text Link to item Cite

Orthopaedic trauma for the general orthopaedist: avoiding problems and pitfalls in treatment.

Journal Article Clin Orthop Relat Res · April 2005 The Advanced Trauma Life Support program of the American College of Surgeons has developed a de facto standard of care for the first hour of treatment of patients with trauma who are treated in North America. No equivalent for the treatment of orthopaedic ... Link to item Cite

Classification and initial management of patients with unstable pelvic ring injuries.

Journal Article Instr Course Lect · 2005 Unstable pelvic ring injuries in hemodynamically unstable patients are life-threatening emergencies that many orthopaedic surgeons encounter in practice. Therefore, it is important to be up to date regarding current methods of evaluating, assessing, and tr ... Link to item Cite

Development of an animal model of acetabular fractures.

Journal Article Clinical orthopaedics and related research · June 2004 A closed intraarticular fracture is a complex injury that consists of a physical disruption of the subchondral bone and articular surface, and an impaction injury to the articular surface that occurs at the time of the fracture. Few experimental models hav ... Full text Cite

The role of biomechanics and inflammation in cartilage injury and repair.

Journal Article Clin Orthop Relat Res · June 2004 Osteoarthritis is a painful and debilitating disease characterized by progressive degenerative changes in the articular cartilage and other joint tissues. Biomechanical factors play a critical role in the initiation and progression of this disease, as evid ... Full text Link to item Cite

Posttraumatic osteoarthritis.

Journal Article Clin Orthop Relat Res · June 2004 Link to item Cite

Pulmonary aspects of treatment of long bone fractures in the polytrauma patient.

Journal Article Clin Orthop Relat Res · May 2004 During the past decade, there have been significant advances in the treatment of long bone fractures in the polytraumatized patient. The major controversy in this area is whether definitive long bone stabilization needs to be done emergently. In general, d ... Full text Link to item Cite

Femur fractures and lung complications: a prospective randomized study of reaming.

Journal Article Clin Orthop Relat Res · May 2004 Featured Publication Reaming the intramedullary canal during fixation of femoral shaft fractures may contribute to pulmonary morbidity in patients with trauma. The purpose of our study was to compare acute and late pulmonary complications after reamed or nonreamed nailing of f ... Link to item Cite

Femur Fractures and Lung Complications

Journal Article Clinical Orthopaedics and Related Research · May 2004 Full text Cite

Are recombinant human bone morphogenetic protein-7 and tobramycin compatible? An experiment in rats.

Journal Article J Orthop Trauma · April 2004 OBJECTIVES: To evaluate the effects of local antibiotics on bone morphogenetic protein-induced new bone formation in vivo. DESIGN: In the research laboratory, inactive collagenous bone matrix was reconstituted with 1 microg of recombinant human bone morpho ... Full text Link to item Cite

Posttraumatic osteoarthritis.

Journal Article Clinical orthopaedics and related research · January 1, 2004 Open Access Cite

Articular fractures.

Journal Article J Am Acad Orthop Surg · 2004 Although injuries to articular cartilage may lead to radiographic osteoarthritis, pain, and decreased joint function, the actual effects of such injury and of its treatment on joint function are not completely understood. The mechanisms of repair after imp ... Full text Link to item Cite

Articular fractures: Editorial comment

Journal Article Clinical Orthopaedics and Related Research · January 1, 2004 Cite

Biomechanical comparison of posterior pelvic ring fixation.

Journal Article J Orthop Trauma · August 2003 OBJECTIVE: To determine relative stiffness of various methods of posterior pelvic ring internal fixation. DESIGN: Simulated single leg stance loading of OTA 61-Cl.2, a2 fracture model (unilateral sacroiliac joint disruption and pubic symphysis diastasis). ... Full text Link to item Cite

Early versus delayed stabilization of femoral fractures.

Journal Article The Journal of bone and joint surgery. American volume · July 2003 Cite

Open fractures of the tibial shaft: an update.

Journal Article Instr Course Lect · 2003 The treatment of open fractures of the tibial shaft continues to be a challenging problem for the orthopaedic surgeon. The basic principles of treatment for open fractures have changed little over the past decade; urgent wound dĂ©bridement, early use of ant ... Link to item Cite

Incision placement for intramedullary tibial nailing: an anatomic study.

Journal Article J Orthop Trauma · 2002 OBJECTIVES: For intramedullary nailing of tibial shaft fractures, a recent study has determined that the entry site should be just medial to the lateral tibial spine at the anterior margin of the articular surface. Gaining access to this site is often thro ... Full text Link to item Cite

Open fractures

Chapter · 2001 Cite

Acetabular fracture.

Journal Article J Orthop Trauma · November 2000 A twenty-eight-year-old female bicyclist was struck by a car. Associated injuries after trauma work-up included a splenic laceration that is to be treated with observation and a history of loss of consciousness with a negative head CT. X-rays and represent ... Full text Link to item Cite

Open reduction and internal fixation

Journal Article JOURNAL OF ORTHOPAEDIC TRAUMA · November 1, 2000 Link to item Cite

Superior gluteal artery in the extended iliofemoral approach.

Journal Article J Orthop Trauma · May 2000 OBJECTIVE: To determine the incidence of superior gluteal artery injury following fracture of the acetabulum and to determine whether the combination of a superior gluteal artery injury and the use of an extended iliofemoral approach to the acetabulum crea ... Full text Link to item Cite

Factors related to hip muscle weakness following fixation of acetabular fractures.

Journal Article Orthopedics · March 2000 Two hundred twenty-five acetabular fractures treated surgically by one surgeon using a single surgical approach were reviewed to identify the incidence of clinically significant hip muscle weakness. Clinical grade of fair or poor and presence of radiograph ... Full text Link to item Cite

Comparison of antibiotic beads and intravenous antibiotics in open fractures.

Journal Article Clin Orthop Relat Res · March 2000 This study compared the efficacy of antibiotic impregnated beads with conventional intravenous antibiotics in the treatment of open fractures. A randomized prospective study was designed and conducted during a 29-month period. Sixty-seven patients with 75 ... Full text Link to item Cite

Biomechanical evaluation of impaction fractures of the femoral head.

Journal Article J Orthop Trauma · August 1999 OBJECTIVES: To measure the effect of an impaction fracture of the femoral head on load transmission in the hip joint. DESIGN: We measured the contact areas and pressure between the acetabulum and femoral head of cadaveric pelves in four different condition ... Full text Link to item Cite

Surgical treatment of acetabular fractures.

Journal Article Instr Course Lect · 1999 Link to item Cite

Posterior wall fractures

Journal Article Operative Techniques in Orthopaedics · January 1, 1999 The goal of surgical treatment of posterior wall fractures is to obtain stability of the hip by restoring the normal shape of the acetabulum and to restore the normal pressure distribution within the joint by anatomic reduction of the articular surface. Fr ... Full text Cite

The role of the acetabular labrum and the transverse acetabular ligament in load transmission in the hip.

Journal Article J Bone Joint Surg Am · December 1998 Featured Publication We performed a biomechanical study of seventeen hip joints in the pelves of nine cadavera in order to assess the role that the acetabular labrum and the transverse acetabular ligament play in load transmission. The distribution of contact area and pressure ... Full text Link to item Cite

Posttraumatic lymphocyte response: a comparison between peripheral blood T cells and tissue T cells.

Journal Article J Trauma · July 1998 BACKGROUND: T-cell response to trauma has been assessed primarily by sampling peripheral blood lymphocytes. We hypothesized that lymphocytes residing in tissue and traveling through lymph vessels are more likely to be activated by tissue injury and hemorrh ... Full text Link to item Cite

Consequences of transverse acetabular fracture malreduction on load transmission across the hip joint.

Journal Article J Orthop Trauma · February 1998 OBJECTIVE: To evaluate the biomechanical behavior of gap and step malreductions in a model of transverse acetabular fracture. DESIGN: Cadaver pelvis loading in simulated single-leg stance with intact acetabulum, after transverse acetabular fracture anatomi ... Full text Link to item Cite

Biomechanical evaluation of a low anterior wall fracture: correlation with the CT subchondral arc.

Journal Article J Orthop Trauma · 1998 OBJECTIVE: To measure the effect of a simulated low anterior wall fracture of the acetabulum on load transmission in the hip joint. DESIGN: We measured the contact areas and pressure between the acetabulum and the femoral head of cadaveric pelves in three ... Full text Link to item Cite

Biomechanical consequences of anterior column fracture of the acetabulum.

Journal Article J Orthop Trauma · 1998 OBJECTIVES: To measure biomechanical consequences of a high anterior column acetabular fracture. DESIGN: A benchtop biomechanical model using quasi-static loading of the hip joint in a simulated single-leg stance. Pressure-sensitive prescale (Fuji) film wa ... Full text Link to item Cite

Biomechanics of the hip joint and the effects of fracture of the acetabulum.

Journal Article Clin Orthop Relat Res · June 1997 Featured Publication The biomechanical analysis of the normal and arthritic hip joint have been the subject of numerous publications in orthopaedics. Biomechanical investigations focusing on the effect of fractures of the acetabulum on the alteration of hip joint mechanics hav ... Full text Link to item Cite

Reamed femoral nailing in patients with multiple injuries. Adverse effects of tourniquet use.

Journal Article Clin Orthop Relat Res · June 1997 Limb reperfusion after tourniquet ischemia causes pulmonary microvascular injury. Similarly, microembolization, like that associated with reamed femoral nailing, can induce pulmonary microvascular injury. Both processes result in increased pulmonary capill ... Full text Link to item Cite

Diagnosis and management of closed internal degloving injuries associated with pelvic and acetabular fractures: the Morel-Lavallée lesion.

Journal Article J Trauma · June 1997 Closed internal degloving is a significant soft-tissue injury associated with a pelvic trauma in which the subcutaneous tissue is torn away from the underlying fascia, creating a cavity filled with hematoma and liquefied fat. It commonly occurs over the gr ... Full text Link to item Cite

Nonreamed locking intramedullary nailing for open fractures of the tibia.

Journal Article Clinical orthopaedics and related research · June 1997 The use of nonreamed interlocking tibial nails in the management of open fractures of the tibial shaft has gained wide acceptance. This technique has been reported to have reproducible good results with a low incidence of complications in Type I, Type II, ... Full text Cite

Statically equivalent load and support conditions produce different hip joint contact pressures and periacetabular strains.

Journal Article J Biomech · February 1997 The hip is a common site of orthopaedic trauma and disease, and considerable research has been directed toward understanding the development of contact pressures within the joint. Virtually all experimental studies to date have employed proximal femurs com ... Full text Link to item Cite

Open fractures of the tibial shaft.

Journal Article Instr Course Lect · 1997 Link to item Cite

Amputation versus limb salvage.

Journal Article Instr Course Lect · 1997 The decision to attempt salvage or to amputate a severely injured leg in among the most difficult that the orthopaedist must face. Even surgeons with tremendous trauma experience cannot agree on standard course of action. In the face of such injuries, phys ... Link to item Cite

Assessment of pelvic ring stability after injury. Indications for surgical stabilization.

Journal Article Clin Orthop Relat Res · August 1996 The indications for surgical stabilization of pelvic ring injuries are based on an assessment of the extent of disruption of the pelvic ring and the associated deformity of the bony pelvis. The relevant anatomy and biomechanics or the pelvis, pelvic ring i ... Full text Link to item Cite

Internal fixation of displaced fractures of the sacrum.

Journal Article Clin Orthop Relat Res · August 1996 The results of internal fixation in 30 patients with displaced fractures of the sacrum were retrospectively reviewed. All fractures were displaced at least 1 cm. Neurologic injuries occurred in 40% (12 of 30) patients. In 17 patients who underwent open red ... Full text Link to item Cite

Open fractures

Chapter · 1996 Cite

Removal of intramedullary nails from the femur: a review of 45 cases.

Journal Article J Orthop Trauma · 1996 The excellent biocompatibility of titanium and its alloys may result in osseointegration. In order to determine if this presents an obstacle to removal of intramedullary nails, we retrospectively reviewed a series of 45 cases of isolated removal of a femor ... Full text Link to item Cite

The effect of variable size posterior wall acetabular fractures on contact characteristics of the hip joint.

Journal Article J Orthop Trauma · 1996 The indications for open reduction and internal fixation of posterior wall acetabular fractures associated with a clinically stable hip joint are unclear. In previous work a large posterior wall defect (27% articular surface area) resulted in significant a ... Full text Link to item Cite

Open fractures of the tibial shaft. Current treatment

Journal Article Journal of Bone and Joint Surgery · January 1, 1996 Full text Cite

Biomechanical consequences of fracture and repair of the posterior wall of the acetabulum.

Journal Article J Bone Joint Surg Am · August 1995 We measured the distribution of contact area and pressure between the acetabulum and the femoral head of cadaveric pelves in three different conditions: intact, with an operatively created fracture of the posterior wall, and after anatomical reduction and ... Full text Link to item Cite

Anatomy of the medial distal femur: a study of the adductor hiatus.

Journal Article J Orthop Trauma · February 1995 The proximity of the vascular structures traversing the adductor hiatus in the medial distal femur is a potential concern for the surgeon. The distance from the adductor tubercle to the adductor hiatus was measured in both lower extremities in 24 skeletall ... Full text Link to item Cite

The computerized tomography subchondral arc: a new method of assessing acetabular articular continuity after fracture (a preliminary report).

Journal Article J Orthop Trauma · 1993 The criteria to treat acetabular fractures operatively versus nonoperatively continue to evolve. The technique of roof arc measurements was developed to identify the extent of superior acetabulum left intact after fracture. Computerized tomography (CT) of ... Full text Link to item Cite

A review of computerized tomography evaluation of acetabular fractures--part 2

Journal Article Contemporary Orthopaedics · October 1991 Cite

A review of computerized tomography evaluation of acetabular fractures--part 1.

Journal Article Contemp Orthop · October 1991 Computerized tomography is an established modality for use in the evaluation of acetabular fractures. As open reduction and internal fixation of acetabular fractures becomes more common, the need for an accurate understanding of the fracture anatomy is cri ... Link to item Cite

Magnetic resonance imaging evaluation of the spinal canal following arthrodesis and removal of sublaminar wires.

Journal Article Spine (Phila Pa 1976) · August 1991 Seven patients who underwent posterior spinal fusion with Harrington instrumentation and sublaminar wires, and subsequently had these implants removed, were evaluated for evidence of spinal canal compromise with magnetic resonance imaging (MRI) at the site ... Link to item Cite

Magnetic resonance imaging evaluation of the spinal canal following arthrodesis and removal of sublaminar wires

Journal Article Spine · January 1, 1991 Seven patients who underwent posterior spinal fusion with Harrington instrumentation and sublaminar wires, and subsequently had these implants removed, were evaluated for evidence of spinal canal compromise with magnetic resonance imaging (MRI) at the site ... Full text Cite

Disseminated intravascular coagulation complicating Ender's nailing of a pathologic fracture in prostatic carcinoma. A case report.

Journal Article Clin Orthop Relat Res · September 1990 Disseminated intravascular coagulation (DIC) occurred after closed Ender's pinning of a pathologic fracture of the humerus in a 58-year-old man with metastatic prostatic carcinoma. A review of the oncologic and urologic literature revealed that coagulopath ... Link to item Cite

Combined entrapment of the median and anterior interosseous nerves in a pediatric both-bone forearm fracture.

Journal Article J Orthop Trauma · 1990 Unrecognized entrapment of the median nerve and its anterior interosseous branch in the midportion of the forearm occurred in a 12-year-old girl following reduction of a closed both-bone fracture. Following delayed diagnosis, treatment required secondary n ... Full text Link to item Cite

Metatarsal head resection for rheumatoid deformities of the forefoot.

Journal Article Clin Orthop Relat Res · May 1988 Thirty-five feet in 21 patients, who had had metatarsal head resection for painful rheumatoid forefoot deformities, were analyzed retrospectively. All patients but one were allowed to ambulate 48 hours after surgery. The follow-up period averaged 29 months ... Link to item Cite

Removal of sublaminar wires after spinal fusion.

Journal Article J Bone Joint Surg Am · December 1987 Eighteen patients who had had spinal fusion using Harrington rods with sublaminar wires underwent removal of the implants because of tenderness over the implants. There were no important complications. At final follow-up, no patient had a change in neurolo ... Link to item Cite

Compartment syndrome: pathophysiology, diagnosis, and treatment.

Journal Article Surgical Rounds for Orthopaedics · 1987 Cite

Abnormalities of the cervical spine in Down's syndrome: diagnosis, risks, and review of the literature, with particular reference to the Special Olympics.

Journal Article South Med J · January 1987 Over a four-month period, we did roentgenographic examinations of the cervical spine on 35 individuals with Down's syndrome, most of whom planned to participate in the Special Olympics. There were abnormalities in 40%, the most frequent being atlantoaxial ... Full text Link to item Cite

Preface

Book · 1986 Cite