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Paul Grimsrud

Assistant Professor in Medicine
Medicine, Endocrinology, Metabolism, and Nutrition
104775, Durham, NC 27701
300 N Duke Street, 48-208K, Durham, NC 27701

Selected Grants


Mechanisms of lipid-induced bioenergetic stress in muscle

ResearchCo Investigator · Awarded by National Institutes of Health · 2010 - 2028

Novel roles of PDK4 in regulating mitochondrial protein phosphorylation, carbon flux and metabolic resilience

ResearchCo-Principal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2022 - 2027

Probing the Role of Mitochondrial Short-chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchInvestigator · Awarded by University of Pennsylvania · 2021 - 2025

Studies on the impact of acetyl-cysteine on metabolism

ResearchResearch Scientist · Awarded by National Institute on Aging · 2022 - 2024

NCDRC P&F April 2022

ResearchPrincipal Investigator · Awarded by Wake Forest University · 2021 - 2023

The Role of ChREBP in Fructose Induced Metabolic Disease

ResearchResearch Scientist · Awarded by National Institutes of Health · 2014 - 2022

Post-Translational and Epigenetic Control of Branched-Chain Amino Acid Metabolism

ResearchResearch Scientist · Awarded by National Institutes of Health · 2018 - 2022

AHA Career Development Award

ResearchPrincipal Investigator · Awarded by American Heart Association · 2018 - 2021

Probing the Role of Mitochondrial Short-Chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchCo Investigator · Awarded by University of Pennsylvania · 2017 - 2021

Mitochondrial Protein Acetylation and Energy Metabolism in Muscle

FellowshipConsultant · Awarded by National Institutes of Health · 2015 - 2018

Role of Protein Malonylation in Regulating Mitochondrial Function

FellowshipCollaborator · Awarded by National Institutes of Health · 2015 - 2017

Novel SIRT4 Enzymatic Activity Influence Cellular Mechanisms of Aging

ResearchInvestigator · Awarded by National Institutes of Health · 2016 - 2017

Probing the role of Mitochondrial Short-Chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchResearch Scientist · Awarded by Sanford-Burnham Medical Research Institute · 2017 - 2017

Fellowships, Gifts, and Supported Research


Borden Scholars Award · April 1, 2022 - March 31, 2023 PI · Awarded by: Duke University School of Medicine · $50,000.00
Career Development Award (18CDA34110216) · June 1, 2018 - June 30, 2021 PI · Awarded by: American Heart Association · $77,000.00
Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship (1F32DK091049-01A1) · September 1, 2011 - August 31, 2014 PI · Awarded by: National Institutes of Health/ National Institute of Diabetes and Digestive and Kidney Diseases · $53,000.00
Institutional National Research Service Award (2T32HL007741-11) · July 26, 2004 - July 25, 2007 Graduate Trainee · Awarded by: National Institutes of Health/National Heart, Lung, and Blood Institute · $20,772.00