Pedro Vicente Rada Rincon

Pedro Vicente Rada Rincon
Senior Lecturer in Neuroscience at Duke Kunshan University

His research focuses on the reward mechanism of feeding behavior and drug addiction. While studying both behaviors he found that feeding could become pathological (addiction) if the right conditions were present. Other lines of research are linked to his medical background and incorporate the study of basic mechanisms in diseases such as Parkinson’s, Alzheimer’s, epilepsy and depression.

He is author of several book chapters and his research articles have appeared in peer-reviewed journals such as Journal of Neuroscience, Neuroscience, Neuroscience and Biobehavioral Reviews, and Frontiers in Psychiatry.

He has an M.D. and neurology specialty from Universidad de los Andes, Venezuela, and a Ph.D. in medical sciences neuroscience mention from Universidad del Zulia, Venezuela. He worked for five years as a postdoc and 15 years as a visiting researcher and visiting professor at Princeton University. Before joining Duke Kunshan, he was professor of physiology in the School of Medicine, Universidad de los Andes.

Current Appointments & Affiliations

Senior Lecturer in Neuroscience at Duke Kunshan University, DKU Faculty, Duke Kunshan University 2020

Contact Information

pedro.rada.rincon@dukekunshan.edu.cn

Background
Education, Training, & Certifications
- Ph.D., Universidad del Zulia (Venezuela) 2009
Academic Positions Outside Duke
- Visiting researcher, Princeton University. 2007 - 2008
- Visiting researcher, Princeton University. 2006
- Visiting Professor, Rockefeller University. 2005
- Visiting researcher, Princeton University. 2004
- Visiting researcher (sabbatical), Princeton University. 2002 - 2003
- Visiting researcher, Princeton University. 2001
- Visiting researcher, Princeton University. 2000
- Visiting researcher, Princeton University. 2000
- Visiting researcher, Princeton University. 1999
- Visiting researcher , Princeton University. 1998 - 1999
- Visiting researcher, Princeton University. 1998
- Full professor, Universidad de los Andes, Venezuela. 1998 - 2015
- Visiting researcher, Princeton University. 1997
- Visiting researcher, Princeton University. 1996 - 1997
- Neurologist , University Hospital, Merida, Venezuela. 1996 - 2019
- Visiting researcher, Princeton University. 1995
- Associate professor, Universidad de los Andes, Venezuela. 1994 - 1998
- Postdoctoral fellowship, Princeton University. 1990 - 1994
- Aggregate professor, Universidad de los Andes, Venezuela. 1990 - 1994
- Neurologist , University Hospital, Merida, Venezuela. 1988 - 1990
- Assistant position, Universidad de los Andes, Venezuela. 1987 - 1990
- Neurology Residency, University Hospital, Merida, Venezuela. 1986 - 1988
- Instructor, Universidad de los Andes, Venezuela. 1983 - 1987
- Medical Intern, Hospital IVSS, San Cristobal, Venezuela. 1982 - 1983
- Medical Intern community work, San Jose de Acequias, Venezuela. 1982 - 1983
- Student teaching assitant, Universidad de los Andes, Venezuela. 1978 - 1981
Expertise
Subject Headings
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Rada Rincon, Pedro, Sergio Sacchettoni, Juan Felix Del Corral, and Luis Hernandez. “Dynamic Cerebral Microdialysis during Pallidotomy and Thalamotomy in Parkinson’s Disease: A Preliminary Neurochemical Study.” Open Journal of Modern Neurosurgery 10 (2020): 284–96.
  - Rada Rincon, Pedro, Sergio Sacchettoni, Juan Felix Del Corral, and Luis Hernandez. “Intracerebral Microdialysis in Neurosurgery for Obsessive-Compulsive Disorder: Report of 2 Preliminary Cases.” Open Journal of Modern Neurosurgery 10 (2020): 371–81.
  - Betancourt, L., P. Rada, L. Hernandez, H. Araujo, G. A. Ceballos, L. E. Hernandez, P. Tucci, Z. Mari, M. De Pasquale, and D. A. Paredes. “Micellar electrokinetic chromatography with laser induced fluorescence detection shows increase of putrescine in erythrocytes of Parkinson's disease patients.” Journal of Chromatography B 1081–1082 (April 2018): 51–57. https://doi.org/10.1016/j.jchromb.2018.02.015.
    Full Text
  - Contreras, Mike T., Maria J. Gallardo, Luis R. Betancourt, Pedro V. Rada, Gerardo A. Ceballos, Luis E. Hernandez, and Luis F. Hernandez. “Correlation between plasma levels of arginine and citrulline in preterm and full-term neonates: Therapeutical implications.” Journal of Clinical Laboratory Analysis 31, no. 6 (November 2017): e22134–e22134. https://doi.org/10.1002/jcla.22134.
    Full Text
  - Calderón, Naima, Luis Betancourt, Luis Hernández, and Pedro Rada. “A ketogenic diet modifies glutamate, gamma-aminobutyric acid and agmatine levels in the hippocampus of rats: A microdialysis study.” Neuroscience Letters 642 (March 2017): 158–62. https://doi.org/10.1016/j.neulet.2017.02.014.
    Full Text
  - Schoenfeld, T. J., P. Rada, P. R. Pieruzzini, B. Hsueh, and E. Gould. “Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus.” Journal of Neuroscience 33, no. 18 (May 1, 2013): 7770–77. https://doi.org/10.1523/jneurosci.5352-12.2013.
    Full Text
  - Terán, Yurbi, Ormelys Ponce, Luis Betancourt, Luis Hernández, and Pedro Rada. “Amino acid profile of plasma and cerebrospinal fluid in preeclampsia.” Pregnancy Hypertension: An International Journal of Women’S Cardiovascular Health 2, no. 4 (October 2012): 416–22. https://doi.org/10.1016/j.preghy.2012.05.001.
    Full Text
  - Chen, Y. -. W., P. V. Rada, B. P. Bützler, S. F. Leibowitz, and B. G. Hoebel. “Corticotropin-releasing factor in the nucleus accumbens shell induces swim depression, anxiety, and anhedonia along with changes in local dopamine/acetylcholine balance.” Neuroscience 206 (March 2012): 155–66. https://doi.org/10.1016/j.neuroscience.2011.12.009.
    Full Text
  - Betancourt, Luis, Pedro Rada, Daniel Paredes, and Luis Hernández. “In vivo monitoring of cerebral agmatine by microdialysis and capillary electrophoresis.” Journal of Chromatography B 880 (January 2012): 58–65. https://doi.org/10.1016/j.jchromb.2011.11.016.
    Full Text
  - Skirzewski, M., W. López, E. Mosquera, L. Betancourt, B. Catlow, M. Chiurillo, N. Loureiro, L. Hernández, and P. Rada. “Enhanced GABAergic tone in the ventral pallidum: memory of unpleasant experiences?” Neuroscience 196 (November 2011): 131–46. https://doi.org/10.1016/j.neuroscience.2011.08.058.
    Full Text
  - Chau, David T., Pedro V. Rada, Kay Kim, Rebecca A. Kosloff, and Bartley G. Hoebel. “Fluoxetine Alleviates Behavioral Depression while Decreasing Acetylcholine Release in the Nucleus Accumbens Shell.” Neuropsychopharmacology 36, no. 8 (July 2011): 1729–37. https://doi.org/10.1038/npp.2011.54.
    Full Text
  - Hernández, Luis, Daniel Paredes, and Pedro Rada. “Feeding behavior as seen through the prism of brain microdialysis.” Physiology & Behavior 104, no. 1 (July 2011): 47–56. https://doi.org/10.1016/j.physbeh.2011.04.031.
    Full Text
  - Rada, Pedro, Miriam E. Bocarsly, Jessica R. Barson, Bartley G. Hoebel, and Sarah F. Leibowitz. “Reduced accumbens dopamine in Sprague–Dawley rats prone to overeating a fat-rich diet.” Physiology & Behavior 101, no. 3 (October 2010): 394–400. https://doi.org/10.1016/j.physbeh.2010.07.005.
    Full Text
  - Skirzewski, Miguel, Luis Hernandez, Lee E. Schechter, and Pedro Rada. “Acute lecozotan administration increases learning and memory in rats without affecting anxiety or behavioral depression.” Pharmacology Biochemistry and Behavior 95, no. 3 (May 2010): 325–30. https://doi.org/10.1016/j.pbb.2010.02.008.
    Full Text
  - Barson, Jessica R., Ambrose J. Carr, Jennifer E. Soun, Nasim C. Sobhani, Pedro Rada, Sarah F. Leibowitz, and Bartley G. Hoebel. “Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake.” Alcoholism: Clinical and Experimental Research 34, no. 2 (February 2010): 214–22. https://doi.org/10.1111/j.1530-0277.2009.01084.x.
    Full Text
  - Rada, Pedro, Jessica R. Barson, Sarah F. Leibowitz, and Bartley G. Hoebel. “Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.” Brain Research 1312 (February 2010): 1–9. https://doi.org/10.1016/j.brainres.2009.11.055.
    Full Text
  - Rada Rincon, Pedro, Sergio Sacchettoni, Juan Del Corral, and Luis Hernandez. “Microdiálisis cerebral, una herramienta promisoria para el studio neuroquímico en neurocirugía: una descroción técnica.” Neurotarget 5 (2010): 30–43.
  - Avena, Nicole M., Pedro Rada, and Bartley G. Hoebel. “Sugar and Fat Bingeing Have Notable Differences in Addictive-like Behavior.” The Journal of Nutrition 139, no. 3 (March 1, 2009): 623–28. https://doi.org/10.3945/jn.108.097584.
    Full Text
  - Hoebel, Bartley G., Nicole M. Avena, Miriam E. Bocarsly, and Pedro Rada. “Natural Addiction.” Journal of Addiction Medicine 3, no. 1 (March 2009): 33–41. https://doi.org/10.1097/adm.0b013e31819aa621.
    Full Text
  - Avena, N. M., P. Rada, and B. G. Hoebel. “Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose.” Neuroscience 156, no. 4 (October 2008): 865–71. https://doi.org/10.1016/j.neuroscience.2008.08.017.
    Full Text
  - Avena, Nicole M., Miriam E. Bocarsly, Pedro Rada, Agnes Kim, and Bartley G. Hoebel. “After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance.” Physiology & Behavior 94, no. 3 (June 2008): 309–15. https://doi.org/10.1016/j.physbeh.2008.01.008.
    Full Text
  - Avena, Nicole M., Pedro Rada, and Bartley G. Hoebel. “Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake.” Neuroscience & Biobehavioral Reviews 32, no. 1 (January 2008): 20–39. https://doi.org/10.1016/j.neubiorev.2007.04.019.
    Full Text
  - Hoebel, Bartley G., Nicole M. Avena, and Pedro Rada. “Accumbens dopamine-acetylcholine balance in approach and avoidance.” Current Opinion in Pharmacology 7, no. 6 (December 2007): 617–27. https://doi.org/10.1016/j.coph.2007.10.014.
    Full Text
  - Schneider, Eve R., Pedro Rada, Ryan D. Darby, Sarah F. Leibowitz, and Bartley G. Hoebel. “Orexigenic Peptides and Alcohol Intake: Differential Effects of Orexin, Galanin, and Ghrelin.” Alcoholism: Clinical and Experimental Research 31, no. 11 (November 2007): 1858–65. https://doi.org/10.1111/j.1530-0277.2007.00510.x.
    Full Text
  - Rada, P., L. Hernandez, and B. G. Hoebel. “Feeding and systemic d-amphetamine increase extracellular acetylcholine in the medial thalamus: A possible reward enabling function.” Neuroscience Letters 416, no. 2 (April 2007): 184–87. https://doi.org/10.1016/j.neulet.2007.02.008.
    Full Text
  - M. Avena, Nicole, Pedro Rada, and Bartley G. Hoebel. “Sugar Bingeing in Rats.” Current Protocols in Neuroscience 36, no. 1 (July 2006). https://doi.org/10.1002/0471142301.ns0923cs36.
    Full Text
  - Avena, N. M., P. Rada, N. Moise, and B. G. Hoebel. “Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response.” Neuroscience 139, no. 3 (January 2006): 813–20. https://doi.org/10.1016/j.neuroscience.2005.12.037.
    Full Text
  - Rada, P., C. Colasante, M. Skirzewski, L. Hernandez, and B. Hoebel. “Behavioral depression in the swim test causes a biphasic, long-lasting change in accumbens acetylcholine release, with partial compensation by acetylcholinesterase and muscarinic-1 receptors.” Neuroscience 141, no. 1 (2006): 67–76. https://doi.org/10.1016/j.neuroscience.2006.03.043.
    Full Text
  - Schechter, L. E., D. L. Smith, S. Rosenzweig-Lipson, S. J. Sukoff, L. A. Dawson, K. Marquis, D. Jones, et al. “Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties.” Journal of Pharmacology and Experimental Therapeutics 314, no. 3 (September 2005): 1274–89. https://doi.org/10.1124/jpet.105.086363.
    Full Text
  - Lewis, M. J., P. Rada, D. F. Johnson, N. M. Avena, S. F. Leibowitz, and B. G. Hoebel. “Galanin and alcohol dependence: Neurobehavioral research.” Neuropeptides 39, no. 3 (June 2005): 317–21. https://doi.org/10.1016/j.npep.2004.12.027.
    Full Text
  - Rada Rincon, Pedro. “Plasma concentrations of serotonin and arginine in patients with cephalalgia.” Gaceta Medica De Caracas 113 (2005): 242–46.
  - Rada Rincon, Pedro. “Addiction to sugar: myth or reality?” Revista Venezolana De Endocrinología Y Metabolismo 3 (2005): 2–12.
  - Rada, P., N. M. Avena, and B. G. Hoebel. “Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell.” Neuroscience 134, no. 3 (January 2005): 737–44. https://doi.org/10.1016/j.neuroscience.2005.04.043.
    Full Text
  - Rada, Pedro, and Bartley G. Hoebel. “Acetylcholine in the accumbens is decreased by diazepam and increased by benzodiazepine withdrawal: a possible mechanism for dependency.” European Journal of Pharmacology 508, no. 1–3 (January 2005): 131–38. https://doi.org/10.1016/j.ejphar.2004.12.016.
    Full Text
  - RADA, P., D. JOHNSON, M. LEWIS, and B. HOEBEL. “In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal.” Pharmacology Biochemistry and Behavior 79, no. 4 (December 2004): 599–605. https://doi.org/10.1016/j.pbb.2004.09.011.
    Full Text
  - RADA, P., N. AVENA, S. LEIBOWITZ, and B. HOEBEL. “Ethanol intake is increased by injection of galanin in the paraventricular nucleus and reduced by a galanin antagonist.” Alcohol 33, no. 2 (June 2004): 91–97. https://doi.org/10.1016/s0741-8329(04)00097-7.
    Full Text
  - Rada, P., S. A. Moreno, S. Tucci, L. E. Gonzalez, T. Harrison, D. T. Chau, B. G. Hoebel, and L. Hernandez. “Glutamate release in the nucleus accumbens is involved in behavioral depression during the Porsolt swim test.” Neuroscience 119, no. 2 (June 2003): 557–65. https://doi.org/10.1016/s0306-4522(03)00162-3.
    Full Text
  - Helm, Katherine A., Pedro Rada, and Bartley G. Hoebel. “Cholecystokinin combined with serotonin in the hypothalamus limits accumbens dopamine release while increasing acetylcholine: a possible satiation mechanism.” Brain Research 963, no. 1–2 (February 2003): 290–97. https://doi.org/10.1016/s0006-8993(02)04051-9.
    Full Text
  - Reyes, Elbert, Sergio Rossell, Daniel Paredes, Pedro Rada, Sonia Tucci, Luis E. Gonzalez, and Luis Hernández. “Haloperidol abolished glutamate release evoked by photic stimulation of the visual cortex in rats.” Neuroscience Letters 327, no. 3 (July 2002): 149–52. https://doi.org/10.1016/s0304-3940(02)00316-6.
    Full Text
  - Colantuoni, Carlo, Pedro Rada, Joseph McCarthy, Caroline Patten, Nicole M. Avena, Andrew Chadeayne, and Bartley G. Hoebel. “Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence.” Obesity Research 10, no. 6 (June 2002): 478–88. https://doi.org/10.1038/oby.2002.66.
    Full Text
  - Glatz, Andrew C., Michelle Ehrlich, Richard S. Bae, Michelle J. Clarke, Patricia A. Quinlan, Emily C. Brown, Pedro Rada, and Bartley G. Hoebel. “Inhibition of cocaine self-administration by fluoxetine or d-fenfluramine combined with phentermine.” Pharmacology Biochemistry and Behavior 71, no. 1–2 (January 2002): 197–204. https://doi.org/10.1016/s0091-3057(01)00657-8.
    Full Text
  - Colantuoni, C., J. Schwenker, J. McCarthy, P. Rada, B. Ladenheim, J. -. L. Cadet, G. J. Schwartz, T. H. Moran, and B. G. Hoebel. “Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain.” Neuroreport 12, no. 16 (November 2001): 3549–52. https://doi.org/10.1097/00001756-200111160-00035.
    Full Text
  - Rada, Pedro, Kristin Jensen, and Bartley Hoebel. “Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens.” Psychopharmacology 157, no. 1 (August 1, 2001): 105–10. https://doi.org/10.1007/s002130100781.
    Full Text
  - Chau, D. T., P. Rada, R. A. Kosloff, J. L. Taylor, and B. G. Hoebel. “Nucleus accumbens muscarinic receptors in the control of behavioral depression: antidepressant-like effects of local M1 antagonist in the Porsolt swim test.” Neuroscience 104, no. 3 (June 2001): 791–98. https://doi.org/10.1016/s0306-4522(01)00133-6.
    Full Text
  - Rada, Pedro V., and Bartley G. Hoebel. “Aversive hypothalamic stimulation releases acetylcholine in the nucleus accumbens, and stimulation-escape decreases it.” Brain Research 888, no. 1 (January 2001): 60–65. https://doi.org/10.1016/s0006-8993(00)02865-1.
    Full Text
  - Tucci, Sonia, Quilianio Contreras, Ximena Paez, Luis Gonzalez, Pedro Rada, and Luis Hernandez. “Medial prefrontal transection enhances social interaction.” Brain Research 887, no. 2 (December 2000): 259–65. https://doi.org/10.1016/s0006-8993(00)02932-2.
    Full Text
  - Pérez, Jaqueline, Cesare Colasante, Sonia Tucci, Luis Hernández, and Pedro Rada. “Effects of feeding on extracellular levels of glutamate in the medial and lateral portion of the globus pallidus of freely moving rats.” Brain Research 877, no. 1 (September 2000): 91–94. https://doi.org/10.1016/s0006-8993(00)02658-5.
    Full Text
  - De Parada, M Puig, M. A. Parada, P. Rada, L. Hernandez, and B. G. Hoebel. “Dopamine–Acetylcholine Interaction in the Rat Lateral Hypothalamus in the Control of Locomotion.” Pharmacology Biochemistry and Behavior 66, no. 2 (June 2000): 227–34. https://doi.org/10.1016/s0091-3057(99)00244-0.
    Full Text
  - Páez, X., P. Rada, and L. Hernández. “Neutral amino acids monitoring in phenylketonuric plasma microdialysates using micellar electrokinetic chromatography and laser-induced fluorescence detection.” Journal of Chromatography B: Biomedical Sciences and Applications 739, no. 2 (March 2000): 247–54. https://doi.org/10.1016/s0378-4347(99)00536-8.
    Full Text
  - Rada, Pedro V., Gregory P. Mark, John J. Yeomans, and Bartley G. Hoebel. “Acetylcholine Release in Ventral Tegmental Area by Hypothalamic Self-Stimulation, Eating, and Drinking.” Pharmacology Biochemistry and Behavior 65, no. 3 (March 2000): 375–79. https://doi.org/10.1016/s0091-3057(99)00218-x.
    Full Text
  - Rada, Pedro V., and Bartley G. Hoebel. “Supraadditive Effect of d-Fenfluramine Plus Phentermine on Extracellular Acetylcholine in the Nucleus Accumbens.” Pharmacology Biochemistry and Behavior 65, no. 3 (March 2000): 369–73. https://doi.org/10.1016/s0091-3057(99)00219-1.
    Full Text
  - Rada Rincon, Pedro, Juan Del Corral, Sergio Sacchettoni, and Luis Hernandez. “Microdialisis en humanos: experiencia en la enfermedad de Parkinson.” Archivos Del Hospital Vargas 42 (2000): 93–96.
  - Paredes, Daniel, Pedro Rada, Ernesto Bonilla, Luis E. Gonzalez, Marco Parada, and Luis Hernandez. “Melatonin acts on the nucleus accumbens to increase acetylcholine release and modify the motor activity pattern of rats.” Brain Research 850, no. 1–2 (December 1999): 14–20. https://doi.org/10.1016/s0006-8993(99)01992-7.
    Full Text
  - Rada, P., S. Tucci, L. Teneud, X. Paez, J. Perez, G. Alba, Y. Garcı́a, S. Sacchettoni, J. del Corral, and L. Hernandez. “Monitoring γ-aminobutyric acid in human brain and plasma microdialysates using micellar electrokinetic chromatography and laser-induced fluorescence detection.” Journal of Chromatography B: Biomedical Sciences and Applications 735, no. 1 (November 1999): 1–10. https://doi.org/10.1016/s0378-4347(99)00386-2.
    Full Text
  - CHAU, D. A. V. I. D., PEDRO V. RADA, REBECCA A. KOSLOFF, and BARTLEY G. HOEBEL. “Cholinergic, M1 Receptors in the Nucleus Accumbens Mediate Behavioral Depression: A Possible Downstream Target for Fluoxetine.” Annals of the New York Academy of Sciences 877, no. 1 ADVANCING FRO (June 1999): 769–74. https://doi.org/10.1111/j.1749-6632.1999.tb09320.x.
    Full Text
  - Rada, Pedro, Sonia Tucci, Jackeline Pérez, Luis Teneud, Susana Chuecos, and Luis Hernández. “In vivo monitoring of gabapentin in rats: A microdialysis study coupled to capillary electrophoresis and laser-induced fluorescence detection.” Electrophoresis 19, no. 16–17 (November 1998): 2976–80. https://doi.org/10.1002/elps.1150191629.
    Full Text
  - Tucci, Sonia, Pedro Rada, and Luis Hernandez. “Role of glutamate in the amygdala and lateral hypothalamus in conditioned taste aversion.” Brain Research 813, no. 1 (November 1998): 44–49. https://doi.org/10.1016/s0006-8993(98)00884-1.
    Full Text
  - Rada, Pedro, Gregory P. Mark, and Bartley G. Hoebel. “Galanin in the hypothalamus raises dopamine and lowers acetylcholine release in the nucleus accumbens: a possible mechanism for hypothalamic initiation of feeding behavior.” Brain Research 798, no. 1–2 (July 1998): 1–6. https://doi.org/10.1016/s0006-8993(98)00315-1.
    Full Text
  - Sepulveda, M Jacqueline, Luis Hernandez, Pedro Rada, Sonia Tucci, and Enrique Contreras. “Effect of Precipitated Withdrawal on Extracellular Glutamate and Aspartate in the Nucleus Accumbens of Chronically Morphine-Treated Rats: An In Vivo Microdialysis Study.” Pharmacology Biochemistry and Behavior 60, no. 1 (May 1998): 255–62. https://doi.org/10.1016/s0091-3057(97)00550-9.
    Full Text
  - Baptista, Trino, Hilarion Araujo, Pedro Rada, and Luis Hernández. “Congenital neuroblastoma in a bot born to a woman with bipolar disorder treated with carbamazepine during pregnancy.” Progress in Neuro Psychopharmacology and Biological Psychiatry 22, no. 3 (April 1998): 445–54. https://doi.org/10.1016/s0278-5846(98)00016-5.
    Full Text
  - Tucci, Sonia, Claudio Pinto, Jose Goyo, Pedro Rada, and Luis Hernández. “Measurement of Glutamine and Glutamate by Capillary Electrophoresis and Laser Induced Fluorescence Detection in Cerebrospinal Fluid of Meningitis Sick Children.” Clinical Biochemistry 31, no. 3 (April 1998): 143–50. https://doi.org/10.1016/s0009-9120(98)00003-4.
    Full Text
  - Rada, Pedro V., Gregory P. Mark, and Bartley G. Hoebel. “Dopamine release in the nucleus accumbens by hypothalamic stimulation-escape behavior.” Brain Research 782, no. 1–2 (January 1998): 228–34. https://doi.org/10.1016/s0006-8993(97)01283-3.
    Full Text
  - Guzman, Norberto A., SungAe S. Park, Daniel Schaufelberger, Luis Hernandez, Ximena Paez, Pedro Rada, Andy J. Tomlinson, and Stephen Naylor. “New approaches in clinical chemistry: on-line analyte concentration and microreaction capillary electrophoresis for the determination of drugs, metabolic intermediates, and biopolymers in biological fluids.” Journal of Chromatography B: Biomedical Sciences and Applications 697, no. 1–2 (September 1997): 37–66. https://doi.org/10.1016/s0378-4347(97)00275-2.
    Full Text
  - Rada, P., S. Tucci, E. Murzi, and L. Hernández. “Extracellular glutamate increases in the lateral hypothalamus and decreases in the nucleus accumbens during feeding.” Brain Research 768, no. 1–2 (September 1997): 338–40. https://doi.org/10.1016/s0006-8993(97)00788-9.
    Full Text
  - Tucci, Sonia, Pedro Rada, M Jacqueline Sepúlveda, and Luis Hernandez. “Glutamate measured by 6-s resolution brain microdialysis: capillary electrophoretic and laser-induced fluorescence detection application.” Journal of Chromatography B: Biomedical Sciences and Applications 694, no. 2 (July 1997): 343–49. https://doi.org/10.1016/s0378-4347(96)00488-4.
    Full Text
  - Murzi, E., P. Rada, M. Puig de Parada, M. A. Parada, B. Valecillos, C. A. Tilac, and L. Hernandez. “Atropine decreases drinking but not feeding and induces less hypothalamic acetylcholine release in diabetic rats.” Brain Research 752, no. 1–2 (March 1997): 184–88. https://doi.org/10.1016/s0006-8993(96)01442-4.
    Full Text
  - Mark, G. P., P. V. Rada, and T. J. Shors. “Inescapable stress enhances extracellular acetylcholine in the rat hippocampus and prefrontal cortex but not the nucleus accumbens or amygdala.” Neuroscience 74, no. 3 (August 1996): 767–74. https://doi.org/10.1016/0306-4522(96)00211-4.
    Full Text
  - Páez, Ximena, Pedro Rada, Sonia Tucci, Néstor Rodríguez, and Luis Hernández. “Capillary electrophoresis-laser-induced fluorescence detection of amphetamine in the brain.” Journal of Chromatography A 735, no. 1–2 (May 1996): 263–69. https://doi.org/10.1016/0021-9673(95)00820-9.
    Full Text
  - Rada, P. “Morphine and naloxone, IP or locally, affect extracellular acetylcholine in the accumbens and prefrontal cortex.” Pharmacology Biochemistry and Behavior 53, no. 4 (April 1996): 809–16. https://doi.org/10.1016/0091-3057(95)02078-0.
    Full Text
  - Jones, A. P., E. N. Pothos, P. Rada, D. H. Olster, and B. G. Hoebel. “Maternal hormonal manipulations in rats cause obesity and increase medial hypothalamic norepinephrine release in male offspring.” Developmental Brain Research 88, no. 2 (September 1995): 127–31. https://doi.org/10.1016/0165-3806(95)00078-r.
    Full Text
  - Mark, Gregory P., Jason B. Weinberg, Pedro V. Rada, and Bartley G. Hoebel. “Extracellular acetylcholine is increased in the nucleus accumbens following the presentation of an aversively conditioned taste stimulus.” Brain Research 688, no. 1–2 (August 1995): 184–88. https://doi.org/10.1016/0006-8993(95)00401-b.
    Full Text
  - Parada, M. A., M. Puig de Parada, P. Rada, and L. Hernandez. “Sulpiride increases and dopamine decreases intracranial temperature in rats when injected in the lateral hypothalamus: an animal model for the neuroleptic malignant syndrome?” Brain Research 674, no. 1 (March 1995): 117–21. https://doi.org/10.1016/0006-8993(94)01455-q.
    Full Text
  - HOEBEL, BARTLEY G., P. E. D. R. O. RADA, GREGORY P. MARK, and L. U. I. S. HERNANDEZ. “The Power of Integrative Peptides to Reinforce Behavior by Releasing Dopamine.” Annals of the New York Academy of Sciences 739, no. 1 Models of Neu (October 1994): 36–41. https://doi.org/10.1111/j.1749-6632.1994.tb19805.x.
    Full Text
  - Mark, Gregory P., Sabrina E. Smith, Pedro V. Rada, and Bartley G. Hoebel. “An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release.” Pharmacology Biochemistry and Behavior 48, no. 3 (July 1994): 651–60. https://doi.org/10.1016/0091-3057(94)90327-1.
    Full Text
  - Rada, Pedro V., Gregory P. Mark, and Bartley G. Hoebel. “Effects of supplemental choline on extracellular acetylcholine in the nucleus accumbens during normal behavior and pharmacological acetylcholine depletion.” Synapse 16, no. 3 (March 1994): 211–18. https://doi.org/10.1002/syn.890160306.
    Full Text
  - Rada, Pedro V., Gregory P. Mark, and Bartley G. Hoebel. “In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: I. Inhibition by serotonin.” Brain Research 619, no. 1–2 (August 1993): 98–104. https://doi.org/10.1016/0006-8993(93)91600-w.
    Full Text
  - Rada, Pedro V., Gregory P. Mark, and Bartley G. Hoebel. “In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: II. Inhibition by γ-aminobutyric acid.” Brain Research 619, no. 1–2 (August 1993): 105–10. https://doi.org/10.1016/0006-8993(93)91601-n.
    Full Text
  - Rada, P., M. Parada, and L. Hernandez. “Flexible intravenous microdialysis probe for blood sampling in freely moving rats.” Journal of Applied Physiology 74, no. 1 (January 1, 1993): 466–69. https://doi.org/10.1152/jappl.1993.74.1.466.
    Full Text
  - Mark, Gregory P., Pedro Rada, Emmanuel Pothos, and Bartley G. Hoebel. “Effects of Feeding and Drinking on Acetylcholine Release in the Nucleus Accumbens, Striatum, and Hippocampus of Freely Behaving Rats.” Journal of Neurochemistry 58, no. 6 (June 1992): 2269–74. https://doi.org/10.1111/j.1471-4159.1992.tb10973.x.
    Full Text
  - Pothos, Emmanuel, Pedro Rada, Gregory P. Mark, and Bartley G. Hoebel. “Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment.” Brain Research 566, no. 1–2 (December 1991): 348–50. https://doi.org/10.1016/0006-8993(91)91724-f.
    Full Text
  - Rada, P., G. P. Mark, E. Pothos, and B. G. Hoebel. “Systemic morphine simultaneously decreases extracellular acetylcholine and increases dopamine in the nucleus accumbens of freely moving rats.” Neuropharmacology 30, no. 10 (October 1991): 1133–36. https://doi.org/10.1016/0028-3908(91)90145-2.
    Full Text
  - Rada, Pedro, Emmanuel Pothos, Gregory P. Mark, and Bartley G. Hoebel. “Microdialysis evidence that acetylcholine in the nucleus accumhens is involved in morphine withdrawal and its treatment with clonidine.” Brain Research 561, no. 2 (October 1991): 354–56. https://doi.org/10.1016/0006-8993(91)91616-9.
    Full Text
  - Rada, P., G. P. Mark, M. P. Vitek, R. M. Mangano, A. J. Blume, B. Beer, and B. G. Hoebel. “Interleukin-1 beta decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats.” Brain Res 550, no. 2 (June 7, 1991): 287–90. https://doi.org/10.1016/0006-8993(91)91330-4.
    Full Text Link to Item
  - Rada, P., and L. Hernandez. “Opposite changes of dopamine turnover in prefrontal cortex and nucleus accumbens after amygdaloid kindling.” Neuroscience Letters 117, no. 1–2 (September 1990): 144–48. https://doi.org/10.1016/0304-3940(90)90134-u.
    Full Text
  - Briese, Eduardo, Pedro Rada, and Luis Hernandez. “Electrical hypothalamic stimulation in rats induces hyperthermia if and only if they learn to self-stimulate.” Physiology & Behavior 47, no. 4 (April 1990): 635–39. https://doi.org/10.1016/0031-9384(90)90070-k.
    Full Text
  - Hajnal, András, Gregory P. Mark, Pedro V. Rada, László Lénárd, and Bartley G. Hoebel. “Norepinephrine Microinjections in the Hypothalamic Paraventricular Nucleus Increase Extracellular Dopamine and Decrease Acetylcholine in the Nucleus Accumbens: Relevance to Feeding Reinforcement.” Journal of Neurochemistry 68, no. 2 (n.d.): 667–74. https://doi.org/10.1046/j.1471-4159.1997.68020667.x.
    Full Text
  - Rada Rincon, Pedro, and M. A. Parada. “Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum J Pharmacol Exp Ther . 1997 Apr;281(1):582-8.,” n.d.
  - Rada, Pedro, Ainhoa Mendialdua, Luis Hernandez, and Bartley G. Hoebel. “Extracellular glutamate increases in the lateral hypothalamus during meal initiation and GABA peaks during satiation: Microdialysis measurement every 30 s.” Behavioral Neuroscience 117, no. 2 (n.d.): 222–27. https://doi.org/10.1037/0735-7044.117.2.222.
    Full Text
  - Rada, Pedro, Nicole M. Avena, Jessica R. Barson, Bartley G. Hoebel, and Sarah F. Leibowitz. “A High-Fat Meal, or Intraperitoneal Administration of a Fat Emulsion, Increases Extracellular Dopamine in the Nucleus Accumbens.” Brain Sciences 2, no. 2 (n.d.): 242–53. https://doi.org/10.3390/brainsci2020242.
    Full Text
  - Wiss, David A., Nicole Avena, and Pedro Rada. “Sugar Addiction: From Evolution to Revolution.” Frontiers in Psychiatry 9 (n.d.). https://doi.org/10.3389/fpsyt.2018.00545.
    Full Text
- Book Sections
  - Rada Rincon, Pedro, B. G. Hoebel, and N. M. Avena. “An Accumbens Dopamine-Acetylcholine System for Approach and Avoidance.” In Handbook of Approach and Avoidance Motivation, edited by J. E. Andrew, 89–108. Psychology Press Taylor and Francis Group, 2008.
  - Rada Rincon, Pedro, X. Paez, N. M. Avena, and L. Hernandez. “Microdialysis in Reward and Behavior Inhibition.” In Handbook of Microdialysis Methods, Applications and Perspectives, edited by B. H. C. Westerink, 351–75. Elsevier, 2007.
  - Hernández, Luis, Sergio Rossell, Sonia Tucci, Daniel Paredes, and Pedro Rada. “Chapter 3.3 Improvement of the temporal resolution of brain microdialysis: sampling in seconds.” In Handbook of Microdialysis - Methods, Applications and Perspectives, 267–77. Elsevier, 2006. https://doi.org/10.1016/s1569-7339(06)16015-4.
    Full Text
  - Rada Rincon, Pedro, B. G. Hoebel, G. P. Mark, and E. Pothos. “Neural Systems for Reinforcement and Inhibition of Behavior: Relevance to Eating, Addiction and Depression.” In Understanding Quality of Life: Scientific Perspectives on Enjoyment and Suffering, edited by D. Kahneman, E. Diener, and N. Schwars, 501–49. Russell Sage Foundation, 1999.
  - Hoebel, B. G., P. Rada, G. P. Mark, E. Pothos, M. A. Parada, L. Hernandez, and Pedro Rada Rincon. “Hypothalamic control of accumbens dopamine: a system for feeding reinforcement.” In Molecular and Genetic Aspects of Obesity, 263–80. Baton Rouge: Louisiana State University Press, 1996.
  - Rada Rincon, Pedro, B. G. Hoebel, G. P. Mark, M. A. Parada, and M. Puig. “Hypothalamic control of the mesolimbic reward system: PVN galanin and LH dopamine.” In Progress in Obesity, edited by A. Angel, H. Anderson, C. Bouchard, D. Lau, L. Leiter, and R. Mendelson, 393–97. New York: John Libbey and company ltd, 1996.
  - Rada Rincon, Pedro, L. Betancourt, L. Hernandez, S. Sacchettoni, and H. Araujo. “Clinical Use of Capillary Zone Electrophoresis: New Insights into Parkinson´s Disease.” In Capillary Electrophoresis: Trends and Developments in Pharmaceutical Research, edited by K. Suvardhan, n.d.
  - Rada Rincon, Pedro, L. Betancourt, L. Hernandez, and Maria Gallardo. “Capillary Zone Electrophoresis with Laser Induced Fluorescence (CZE-LIFD): A Method to Explore the Physiological and Pathological Roles of Mono and Polyamines.” In Capillary Electrophoresis (CE): Principles, Challenges and Applications, edited by C. Reed. Nova Science Publishers, n.d.

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Academic Positions Outside Duke

Subject Headings

Selected Publications

Academic Articles

Book Sections