Scholars@Duke
Pedro Vicente Rada Rincon

Pedro Vicente Rada Rincon

Senior Lecturer in Neuroscience at Duke Kunshan University
DKU Faculty

Selected Publications

Sugar Addiction: From Evolution to Revolution

Journal Article Frontiers in Psychiatry · November 7, 2018 Full text Cite

Correlation between plasma levels of arginine and citrulline in preterm and full‐term neonates: Therapeutical implications

Journal Article Journal of Clinical Laboratory Analysis · November 2017 BackgroundPreterm neonates exhibit several deficiencies that endanger their lives. Understanding those disturbances will provide tools for the management of preterm neonates. The present work focuses on arginine a ... Full text Cite

Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus

Journal Article The Journal of Neuroscience · May 1, 2013 Physical exercise is known to reduce anxiety. The ventral hippocampus has been linked to anxiety regulation but the effects of running on this subregion of the hippocampus have been incompletely explored. Here, we investigated the effects of cold w ... Full text Cite

Amino acid profile of plasma and cerebrospinal fluid in preeclampsia

Journal Article Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health · October 2012 Full text Cite

A High-Fat Meal, or Intraperitoneal Administration of a Fat Emulsion, Increases Extracellular Dopamine in the Nucleus Accumbens

Journal Article Brain Sciences · June 11, 2012 Evidence links dopamine (DA) in the nucleus accumbens (NAc) shell to the ingestion of palatable diets. Less is known, however, about the specific relation of DA to dietary fat and circulating triglycerides (TG), which are stimulated by fat intake a ... Full text Cite

Cholinergic modulation of food and drug satiety and withdrawal

Journal Article Physiology & Behavior · June 2012 Full text Cite

Feeding behavior as seen through the prism of brain microdialysis

Journal Article Physiology & Behavior · July 2011 Full text Cite

Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake

Journal Article Alcoholism: Clinical and Experimental Research · February 2010 Background: Specialized hypothalamic systems that increase food intake might also increase ethanol intake. To test this possibility, morphine and receptor‐specific opioid agonists were microinjected in the paraventricular nuc ... Full text Cite

Natural Addiction

Journal Article Journal of Addiction Medicine · March 2009 Full text Cite

Accumbens dopamine-acetylcholine balance in approach and avoidance

Journal Article Current Opinion in Pharmacology · December 2007 Full text Cite

Orexigenic Peptides and Alcohol Intake: Differential Effects of Orexin, Galanin, and Ghrelin

Journal Article Alcoholism: Clinical and Experimental Research · November 2007 Background:  The question is which hypothalamic systems for food intake might play a role in ethanol intake and contribute to alcohol abuse. The peptide orexin was found to exhibit similar properties to galanin in its relatio ... Full text Cite

Sugar Bingeing in Rats

Journal Article Current Protocols in Neuroscience · July 2006 AbstractBingeing behavior is characteristic of many eating disorders. This unit describes an animal model of sugar bingeing. This model has been used successfully to elicit behavioral and neurochemical signs of sugar depend ... Full text Cite

Addiction to sugar: myth or reality?

Journal Article Revista Venezolana de Endocrinología y Metabolismo · 2005 Cite

Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence

Journal Article Obesity Research · June 2002 AbstractObjective: The goal was to determine whether withdrawal from sugar can cause signs of opioid dependence. Because palatable food stimulates neural systems that are implicated in drug addict ... Full text Cite

Medial prefrontal transection enhances social interaction

Journal Article Brain Research · December 2000 Full text Cite

Microdialisis en humanos: experiencia en la enfermedad de Parkinson

Journal Article Archivos del Hospital Vargas · 2000 Cite

In vivo monitoring of gabapentin in rats: A microdialysis study coupled to capillary electrophoresis and laser‐induced fluorescence detection

Journal Article ELECTROPHORESIS · November 1998 AbstractGabapentin (GP) is a new anticonvulsant used in refractory epilepsy. Few studies have monitored the drug in vivo. We report the combination of capillary electrophoresis and laser‐induced f ... Full text Cite

Congenital neuroblastoma in a bot born to a woman with bipolar disorder treated with carbamazepine during pregnancy

Journal Article Progress in Neuro-Psychopharmacology and Biological Psychiatry · April 1998 Full text Cite

Norepinephrine Microinjections in the Hypothalamic Paraventricular Nucleus Increase Extracellular Dopamine and Decrease Acetylcholine in the Nucleus Accumbens: Relevance to Feeding Reinforcement

Journal Article Journal of Neurochemistry · February 1997 Abstract: Norepinephrine (NE) was microinjected into the paraventricular nucleus (PVN), while microdialysis was used to monitor extracellular dopamine (DA) and acetylcholine (ACh) in the nucleus accumbens (NAc). The PVN is a ... Full text Cite

Extracellular acetylcholine is increased in the nucleus accumbens following the presentation of an aversively conditioned taste stimulus.

Journal Article Brain research · August 1995 To determine if acetylcholine (ACh) is released in the nucleus accumbens in response to a conditioned stimulus (CS) that reminds the animal of an aversive event, in vivo microdialysis was used to monitor extracellular ACh during conditioned taste aversion. ... Cite

The Power of Integrative Peptides to Reinforce Behavior by Releasing Dopaminea

Journal Article Annals of the New York Academy of Sciences · October 1994 Full text Cite

Effects of supplemental choline on extracellular acetylcholine in the nucleus accumbens during normal behavior and pharmacological acetylcholine depletion

Journal Article Synapse · March 1994 AbstractBrain microdialysis was used to determine whether systemic or local application of choline would modify the extracellular concentration of acetylcholine (ACh) in the nucleus accumbens (NAc) of freely moving rats. Su ... Full text Cite

Flexible intravenous microdialysis probe for blood sampling in freely moving rats

Journal Article Journal of Applied Physiology · January 1, 1993 A flexible intravenous microdialysis probe was constructed from Silastic tubing (0.5 mm ID and 1.0 mm OD), with a cellulose hollow fiber tip 0.2 mm in diameter and 25 mm long with a 6,000 mol wt cut off. In vitro tests showed relative recovery rat ... Full text Cite

Effects of Feeding and Drinking on Acetylcholine Release in the Nucleus Accumbens, Striatum, and Hippocampus of Freely Behaving Rats

Journal Article Journal of Neurochemistry · June 1992 Abstract: Extracellular levels of acetylcholine (ACh) were measured in the nucleus accumbens (NAC), striatum (STR), and hippocampus (HIPP) using microdialysis in 30‐min intervals before, during, and after free‐feeding in 20‐ ... Full text Cite

Interleukin-1 beta decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats.

Journal Article Brain Res · June 7, 1991 Interleukin (IL-1) is a cytokine which plays an important role in the modulation of the acute response in host defense. This cytokine is also increased in patients with Alzheimer's disease. In the present experiment systemic injection of IL-1 beta (7.5-50 ... Full text Link to item Cite