Philip Martin Rosoff | Scholars@Duke

Philip Martin Rosoff
Professor of Pediatrics

My main interests are clinical ethics with a concentration on the equitable allocation of scarce resources (rationing). In this area, I have done work on planning for pandemic influenza and allocation of drugs during shortages. I play a major role in the Clinical Ethics Service at Duke Hospital and chair the hospital's Ethics Committee.

Current Appointments & Affiliations

Professor of Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 2008
Professor of Medicine, Medicine, Medical Oncology, Medicine 2008

Contact Information

108 Seeley G. Mudd Building, Box 3040, Durham, NC 27710
108 Seeley G. Mudd, Box 3040, Durham, NC 27710
philip.rosoff@duke.edu (919) 668-9000

Background
Education, Training, & Certifications
- M.D., Case Western Reserve University 1978
Duke Appointment History
- Core Faculty in the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2015 - 2018
- Core Faculty in Science & Society, Duke Science & Society, Initiatives 2014 - 2015
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1995 - 2014
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 1996 - 2008
- Associate Professor of Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 1996 - 2008
- Chief, Division of Pediatric Hematology/Oncology, Pediatrics, Hematology-Oncology, Pediatrics 1995 - 2005
- Associate Professor of Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 1996
- Instructor, Temporary of Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 1995 - 1996
Academic Positions Outside Duke
- Adjunct Professor, Dept. of Clinical Sciences, NC State College of Veterinary Medicine. 2018 - 2025
Recognition
In the News
- FEB 4, 2015 The Conversation
  
  Dr. Philip Rosoff: The Affordable Care Act is another way to ration health care
- FEB 4, 2015 The Conversation
  
  The Affordable Care Act is another way to ration health care
- JAN 6, 2015 The Conversation
  
  Dr. Philip Rosoff: What should a hospital do when critical drugs are in short supply?
- JAN 6, 2015 The Conversation
  
  What Should a Hospital Do When Drugs are in Short Supply?
- DEC 18, 2014 The News & Observer
  
  Dr. Philip Rosoff: When doctors take part in torture
- DEC 18, 2014
  
  When Doctors Take Part in Torture
- NOV 13, 2014 ABC News, AP
  
  Dr. Philip Rosoff comments: Ebola drug testing sparks ethics debate
- OCT 31, 2014 Duke Research Blog
  
  Rationing Health Care Is Not a Four-Letter Word
- OCT 14, 2014 The Dallas Morning News
  
  Clinical Trials Needed for Anti-Ebola Drugs
- OCT 14, 2014 The Dallas Morning News
  
  Dr. Philip Rosoff: Clinical trials needed for anti-Ebola drugs
Awards & Honors
Research
Selected Grants
- FitFab 4 Survivors awarded by National Institutes of Health 2011 - 2014
- Gamete Preservation in Males Receiving Gametotoxic Chemotherapy awarded by Josiah Charles Trent Memorial Foundation 2002 - 2003
- Pediatric Oncology Group awarded by National Institutes of Health 1998 - 1999
- Pediatric Oncology Group Studies awarded by National Institutes of Health 1997 - 1999
- Cancer Center Core Support Grant awarded by National Institutes of Health 1976 - 1998
Publications & Artistic Works
Selected Publications
- Books
  - Rosoff, P. M. Drawing the Line: Healthcare Rationing and the Cutoff Problem. New York: Oxford University Press, 2017.
  - Rosoff, Philip M. Rationing Is Not a Four-Letter Word Setting Limits on Healthcare. MIT Press, 2014.
- Academic Articles
  - Adin, Christopher A., Jeannine L. Moga, Bruce W. Keene, Callie A. Fogle, Heather R. Hopkinson, Charity A. Weyhrauch, Steven L. Marks, Rachel J. Ruderman, and Philip M. Rosoff. “Clinical ethics consultation in a tertiary care veterinary teaching hospital..” Journal of the American Veterinary Medical Association 254, no. 1 (January 2019): 52–60. https://doi.org/10.2460/javma.254.1.52.
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  - Hedges, Charles E., and Philip M. Rosoff. “Transplants for non-lethal conditions: a case against hand transplantation in minors..” Journal of Medical Ethics 44, no. 10 (October 2018): 661–65. https://doi.org/10.1136/medethics-2018-104819.
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  - Rosoff, P. M. “Discriminatory Demands by Patients.” Hastings Center Report 48, no. 4 (July 1, 2018): 7–11. https://doi.org/10.1002/hast.863.
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  - Rosoff, Philip M. “When Religion and Medicine Clash: Non-beneficial Treatments and Hope for a Miracle..” Hec Forum : An Interdisciplinary Journal on Hospitals’ Ethical and Legal Issues, June 7, 2018. https://doi.org/10.1007/s10730-018-9352-9.
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  - Rosoff, Philip M., Jeannine Moga, Bruce Keene, Christopher Adin, Callie Fogle, Rachel Ruderman, Heather Hopkinso, and Charity Weyhrauch. “Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model..” The American Journal of Bioethics : Ajob 18, no. 2 (February 2018): 41–53. https://doi.org/10.1080/15265161.2017.1409824.
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  - Rosoff, Philip M., Rachel Ruderman, Jeannine Moga, Bruce Keene, Christopher Adin, Callie Fogle, Heather Hopkinson, and Charity Weyhrauch. “Response to Open Peer Commentaries on "Resolving Ethical Dilemmas in a Tertiary Care Veterinary Specialty Hospital: Adaptation of the Human Clinical Consultation Committee Model"..” The American Journal of Bioethics : Ajob 18, no. 2 (February 2018): W7–10. https://doi.org/10.1080/15265161.2017.1413439.
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  - Rosoff, Philip M. “Compulsory Organ Retrieval: Morally, But Not Socially, Justified..” Cambridge Quarterly of Healthcare Ethics : Cq : The International Journal of Healthcare Ethics Committees 27, no. 1 (January 2018): 36–51. https://doi.org/10.1017/s096318011700038x.
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  - Rosoff, Philip M. “Licensing Surrogate Decision-Makers..” Hec Forum : An Interdisciplinary Journal on Hospitals’ Ethical and Legal Issues 29, no. 2 (June 2017): 145–69. https://doi.org/10.1007/s10730-016-9316-x.
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  - Rosoff, Philip M. “Do Pediatric Patients Have a Right to Know?.” Ama Journal of Ethics 19, no. 5 (May 2017): 426–35. https://doi.org/10.1001/journalofethics.2017.19.5.ecas2-1705.
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  - Waweru-Siika, Wangari, Meredith Edwards Clement, Lilian Lukoko, Simon Nadel, Philip M. Rosoff, Violet Naanyu, and Peter S. Kussin. “Brain death determination: the imperative for policy and legal initiatives in Sub-Saharan Africa..” Global Public Health 12, no. 5 (May 2017): 589–600. https://doi.org/10.1080/17441692.2015.1094108.
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  - Rosoff, Philip M. “Who Should Ration?.” Ama Journal of Ethics 19, no. 2 (February 2017): 164–73. https://doi.org/10.1001/journalofethics.2017.19.2.ecas4-1702.
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  - Rosoff, Philip M., and Lawrence J. Schneiderman. “Irrational Exuberance: Cardiopulmonary Resuscitation as Fetish..” The American Journal of Bioethics : Ajob 17, no. 2 (February 2017): 26–34. https://doi.org/10.1080/15265161.2016.1265163.
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  - Rosoff, Philip M., and Lawrence J. Schneiderman. “Response to Open Peer Commentaries on "Irrational Exuberance: Cardiopulmonary Resuscitation as Fetish"..” The American Journal of Bioethics : Ajob 17, no. 2 (February 2017): W1–3. https://doi.org/10.1080/15265161.2016.1269847.
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  - Hinson, Ashley P., and Philip M. Rosoff. “Where Children Die: Obstacles to Quality End-of-Life Care..” Clinical Pediatrics 55, no. 2 (February 2016): 101–6. https://doi.org/10.1177/0009922815591891.
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  - Rosoff, Philip M. “Making Sausage..” Narrative Inquiry in Bioethics 6, no. 1 (January 2016): 31–33. https://doi.org/10.1353/nib.2016.0029.
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  - Rosoff, Philip M. “In defense of (some) altered standards of care for Ebola infections in developed countries..” Hec Forum : An Interdisciplinary Journal on Hospitals’ Ethical and Legal Issues 27, no. 1 (March 2015): 1–9. https://doi.org/10.1007/s10730-014-9264-2.
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  - Rosoff, Philip M. “Caring for the suffering: meeting the Ebola crisis responsibly..” The American Journal of Bioethics : Ajob 15, no. 4 (January 2015): 26–32. https://doi.org/10.1080/15265161.2015.1010995.
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  - Rosoff, Philip M. “Response to open peer commentaries on "Caring for the suffering: meeting the Ebola crisis responsibly"..” The American Journal of Bioethics : Ajob 15, no. 4 (January 2015): W4–7. https://doi.org/10.1080/15265161.2015.1023116.
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  - Rosoff, Philip M. “TADA Is Still Unfair..” The American Journal of Bioethics : Ajob 15, no. 8 (January 2015): 56–58. https://doi.org/10.1080/15265161.2015.1043406.
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  - Rosoff, Philip M., and Kelly M. Leong. “An Ethical and Legal Framework for Physicians as Surrogate Decision-Makers for Their Patients..” The Journal of Law, Medicine & Ethics : A Journal of the American Society of Law, Medicine & Ethics 43, no. 4 (January 2015): 857–77. https://doi.org/10.1111/jlme.12325.
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  - Falloon, Katie, and Philip M. Rosoff. “Who pays? Mandated insurance coverage for assisted reproductive technology..” The Virtual Mentor : Vm 16, no. 1 (January 2014): 63–69. https://doi.org/10.1001/virtualmentor.2014.16.01.msoc1-1401.
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  - Rosoff, Philip M. “Institutional futility policies are inherently unfair..” Hec Forum : An Interdisciplinary Journal on Hospitals’ Ethical and Legal Issues 25, no. 3 (September 2013): 191–209. https://doi.org/10.1007/s10730-012-9194-9.
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  - Fuemmeler, Bernard F., Margaret K. Pendzich, Kalin Clark, Cheryl Lovelady, Philip Rosoff, Julie Blatt, and Wendy Demark-Wahnefried. “Diet, physical activity, and body composition changes during the first year of treatment for childhood acute leukemia and lymphoma..” Journal of Pediatric Hematology/Oncology 35, no. 6 (August 2013): 437–43. https://doi.org/10.1097/MPH.0b013e318279cd3e.
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  - Raizis, Anthony M., David Van Mater, Lauri A. Aaltonen, Dietmar Lohmann, Michelle S. Cheale, Vivienne M. Bickley, Peter M. George, Yaolin Zhou, and Philip M. Rosoff. “Trilateral retinoblastoma in a patient with Peutz-Jeghers syndrome..” American Journal of Medical Genetics. Part A 161A, no. 5 (May 2013): 1096–1100. https://doi.org/10.1002/ajmg.a.35748.
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  - Coleman, D., and P. Rosoff. “The Legal Authority of Mature Minors to Consent to General Medical Treatment.” Pediatrics 131, no. 4 (2013): 786–93.
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  - Fuemmeler, B. F., M. K. Pendzich, K. Clark, C. Lovelady, P. Rosoff, J. Blatt, and W. Demark-Wahnefried. “Diet, physical activity, and body composition changes during the first year of treatment for childhood acute leukemia and lymphoma.” Journal of Pediatric Hematology/Oncology 35, no. 6 (2013): 437–43. https://doi.org/10.1097/MPH.0b013e318279cd3e.
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  - Raizis, A. M., D. V. Mater, L. A. Aaltonen, D. Lohmann, M. S. Cheale, V. M. Bickley, P. M. George, Y. Zhou, and P. M. Rosoff. “Trilateral Retinoblastoma in a Patient With Peutz-Jeghers Syndrome.” American Journal of Medical Genetics, Part A 161, no. 5 (2013): 1096–1100. https://doi.org/10.1002/ajmg.a.35748.
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  - Rosoff, Philip M., Kuldip R. Patel, Ann Scates, Gene Rhea, Paul W. Bush, and Joseph A. Govert. “Coping with critical drug shortages: an ethical approach for allocating scarce resources in hospitals..” Archives of Internal Medicine 172, no. 19 (October 2012): 1494–99. https://doi.org/10.1001/archinternmed.2012.4367.
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  - Arawi, Thalia, and Philip M. Rosoff. “Competing duties: medical educators, underperforming students, and social accountability..” Journal of Bioethical Inquiry 9, no. 2 (June 2012): 135–47. https://doi.org/10.1007/s11673-012-9365-z.
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  - Rosoff, Philip M. “The myth of genetic enhancement..” Theoretical Medicine and Bioethics 33, no. 3 (June 2012): 163–78. https://doi.org/10.1007/s11017-012-9220-6.
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  - Rosoff, Philip M. “Unpredictable drug shortages: an ethical framework for short-term rationing in hospitals..” The American Journal of Bioethics : Ajob 12, no. 1 (January 2012): 1–9. https://doi.org/10.1080/15265161.2011.634483.
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  - Rosoff, Philip M. “I'll be a monkey's uncle: a moral challenge to human genetic enhancement research..” Journal of Medical Ethics 37, no. 10 (October 2011): 611–15. https://doi.org/10.1136/jme.2010.042226.
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  - Rosoff, Philip M., and Matthew DeCamp. “Preparing for an influenza pandemic: are some people more equal than others?.” Journal of Health Care for the Poor and Underserved 22, no. 3 Suppl (August 2011): 19–35. https://doi.org/10.1353/hpu.2011.0098.
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  - Rosoff, Philip M., and Matthew DeCamp. “Preparing for an Influenza Pandemic: Are Some People More Equal than Others?.” Journal of Health Care for the Poor and Underserved 22, no. 3 (August 1, 2011): 19–35.
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  - Coleman, D., and P. Rosoff. “The Case for Legal Regulation of Physicians' Off-Label Prescribing.” Notre Dame Law Review 86 (2011): 649–91.
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  - Rosoff, P. M., and M. DeCamp. “Preparing for an influenza pandemic: Are some people more equal than others?.” Journal of Health Care for the Poor and Underserved 22, no. SUPPL. 3 (January 1, 2011): 19–35. https://doi.org/10.1353/hpu.2011.0098.
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  - Rosoff, Philip M. “Is medical ethics education effective?.” Le Journal Medical Libanais. the Lebanese Medical Journal 59, no. 1 (January 2011): 12–16.
  - Paxton, Raheem J., Lee W. Jones, Philip M. Rosoff, Melanie Bonner, Joann L. Ater, and Wendy Demark-Wahnefried. “Associations between leisure-time physical activity and health-related quality of life among adolescent and adult survivors of childhood cancers..” Psycho Oncology 19, no. 9 (September 2010): 997–1003. https://doi.org/10.1002/pon.1654.
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  - Rosoff, P. M. “In search of the mommy gene: Truth and consequences in behavioral genetics.” Science Technology and Human Values 35, no. 2 (March 1, 2010): 200–243. https://doi.org/10.1177/0162243909340260.
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  - Rosoff, Philip M. “Should palliative care be a necessity or a luxury during an overwhelming health catastrophe?.” The Journal of Clinical Ethics 21, no. 4 (January 2010): 312–20.
  - Bruce, Courtenay R., Anne Lederman Flamm, Thomas W. Leblanc, and Philip M. Rosoff. “Is there a duty to inform patients of phase I trials?.” The Virtual Mentor : Vm 11, no. 3 (January 2009): 207–14. https://doi.org/10.1001/virtualmentor.2009.11.3.ccas2-0903.
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  - Rosoff, Philip M. “Perspective roundtable: lethal injection..” The New England Journal of Medicine 358, no. 20 (May 2008). https://doi.org/10.1056/nejmc080362.
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  - Hardy, Kristina K., Melanie J. Bonner, Rachel Masi, Katherine C. Hutchinson, Victoria W. Willard, and Philip M. Rosoff. “Psychosocial functioning in parents of adult survivors of childhood cancer..” Journal of Pediatric Hematology/Oncology 30, no. 2 (February 2008): 153–59. https://doi.org/10.1097/mph.0b013e31815814d9.
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  - Arroyave, Whitney D., Elizabeth C. Clipp, Paige E. Miller, Lee W. Jones, Dianne S. Ward, Melanie J. Bonner, Philip M. Rosoff, Denise Clutter Snyder, and Wendy Demark-Wahnefried. “Childhood cancer survivors' perceived barriers to improving exercise and dietary behaviors..” Oncology Nursing Forum 35, no. 1 (January 2008): 121–30. https://doi.org/10.1188/08.onf.121-130.
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  - Rosoff, Philip M. “The ethics of care: social workers in an influenza pandemic..” Social Work in Health Care 47, no. 1 (January 2008): 49–59. https://doi.org/10.1080/00981380801970814.
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  - Rosoff, Philip M. “Physician responsibility for patients' quality of life..” The Virtual Mentor : Vm 10, no. 6 (January 2008): 401–3. https://doi.org/10.1001/virtualmentor.2008.10.6.msoc1-0806.
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  - Sevilla, Deborah W., Jerald Z. Gong, Barbara K. Goodman, Patrick J. Buckley, Philip Rosoff, Jon P. Gockerman, and Anand S. Lagoo. “Clinicopathologic findings in high-grade B-cell lymphomas with typical Burkitt morphologic features but lacking the MYC translocation..” American Journal of Clinical Pathology 128, no. 6 (December 2007): 981–91. https://doi.org/10.1309/c1pp15p7cdb8uy39.
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  - Saini, Shermini, and Philip M. Rosoff. “Are we finally ready for outpatient management of febrile neutropenia?.” Pediatric Blood & Cancer 49, no. 6 (November 2007): 765–66. https://doi.org/10.1002/pbc.21224.
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  - Rosoff, P. M. “Dr. Rosoff replies [13].” New England Journal of Medicine 356, no. 2 (January 11, 2007): 193–94.
  - Rosoff, Philip M. “Survivors of childhood cancer - Reply.” New England Journal of Medicine 356, no. 2 (January 11, 2007): 193–94.
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  - Rosoff, Philip M. “A central role for palliative care in an influenza pandemic..” Journal of Palliative Medicine 9, no. 5 (October 2006): 1051–53. https://doi.org/10.1089/jpm.2006.9.1051.
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  - Rosoff, Philip M. “The two-edged sword of curing childhood cancer..” The New England Journal of Medicine 355, no. 15 (October 2006): 1522–23. https://doi.org/10.1056/nejmp068168.
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  - Rosoff, Philip M., and Alex Rosenberg. “How Darwinian reductionism refutes genetic determinism..” Studies in History and Philosophy of Biological and Biomedical Sciences 37, no. 1 (March 2006): 122–35. https://doi.org/10.1016/j.shpsc.2005.12.005.
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  - Rosoff, Philip M., Nicole Larrier, and Henry E. Rice. “Intra-abdominal desmoid tumor after successful treatment for Hodgkin disease..” Pediatric Blood & Cancer 45, no. 5 (October 2005): 728–31. https://doi.org/10.1002/pbc.20288.
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  - Demark-Wahnefried, Wendy, Cary Werner, Elizabeth C. Clipp, Ann Bebe Guill, Melanie Bonner, Lee W. Jones, and Philip M. Rosoff. “Survivors of childhood cancer and their guardians..” Cancer 103, no. 10 (May 2005): 2171–80. https://doi.org/10.1002/cncr.21009.
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  - Rosoff, Philip M., Cary Werner, Elizabeth C. Clipp, Ann Bebe Guill, Melanie Bonner, and Wendy Demark-Wahnefried. “Response rates to a mailed survey targeting childhood cancer survivors: a comparison of conditional versus unconditional incentives..” Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology 14, no. 5 (May 2005): 1330–32. https://doi.org/10.1158/1055-9965.epi-04-0716.
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  - Tirado, C. A., J. Lager, P. M. Rosoff, V. Golembiski-Ruiz, J. Z. Gong, and B. K. Goodman. “A case of infantile acute lymphoblastic leukemia presenting with rearrangement of MLL at 11q23 and apparent insertion or translocation at 10p12..” Cancer Genetics and Cytogenetics 154, no. 1 (October 2004): 57–59. https://doi.org/10.1016/j.cancergencyto.2004.01.018.
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  - Rosoff, Philip M. “Can underpowered clinical trials be justified?.” Irb 26, no. 3 (May 2004): 16–19. https://doi.org/10.2307/3563753.
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  - Ressler, Ilana B., Jayne Cash, Diana McNeill, Scott Joy, and Philip M. Rosoff. “Continued parental attendance at a clinic for adult survivors of childhood cancer..” Journal of Pediatric Hematology/Oncology 25, no. 11 (November 2003): 868–73. https://doi.org/10.1097/00043426-200311000-00009.
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  - Bayliff, Sherry, Joseph M. Horvatinovich, Jerald Z. Gong, and Philip M. Rosoff. “Lack of circulating megakaryoblasts in newborn peripheral blood: development and validation of a sensitive flow cytometric detection method..” Journal of Pediatric Hematology/Oncology 25, no. 9 (September 2003): 721–25. https://doi.org/10.1097/00043426-200309000-00009.
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  - Uram, Rebecca, and Philip M. Rosoff. “Isolated IgA deficiency after chemotherapy for acute myelogenous leukemia in an infant..” Pediatric Hematology and Oncology 20, no. 6 (September 2003): 487–92. https://doi.org/10.1080/0888001039022017.
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  - Rosoff, Philip M., Elizabeth Tuttle-Newhall, and William R. Treem. “Successful treatment of immune thrombocytopenic purpura with anti-D antibody following a cadaveric liver transplant for hepatoblastoma..” Medical and Pediatric Oncology 40, no. 6 (June 2003): 402–4. https://doi.org/10.1002/mpo.10243.
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  - Rosoff, P. M., H. Moses, E. Braunwald, and J. B. Martin. “Industrial collaboration [5] (multiple letters).” New England Journal of Medicine 348, no. 9 (February 27, 2003): 863–64. https://doi.org/10.1056/NEJM200302273480920.
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  - Rosoff, Philip M. “Industrial collaboration..” The New England Journal of Medicine 348, no. 9 (February 2003): 863–64. https://doi.org/10.1056/nejm200302273480920.
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  - Linardic, Corinne M., Jerald Z. Gong, and Philip M. Rosoff. “Myelodysplasia as masquerader: A woman with hypereosinophilic syndrome and twelve years of "chronic ITP"..” Medical and Pediatric Oncology 39, no. 2 (August 2002): 137–38. https://doi.org/10.1002/mpo.10085.
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  - Paterson, Anne, Sherry Bayliff, George S. Bisset, and Philip M. Rosoff. “Granulocytic sarcoma (chloroma) presenting as a dumbbell tumor..” Pediatric Radiology 32, no. 5 (May 2002): 391–92. https://doi.org/10.1007/s00247-001-0578-2.
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  - Bruno, D., D. R. Wigfall, S. A. Zimmerman, P. M. Rosoff, and J. S. Wiener. “Genitourinary complications of sickle cell disease..” The Journal of Urology 166, no. 3 (September 2001): 803–11. https://doi.org/10.1016/s0022-5347(05)65841-7.
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  - Sugarman, J., and P. M. Rosoff. “Ethical issues in gamete preservation for children undergoing treatment for cancer..” Journal of Andrology 22, no. 5 (September 2001): 732–37.
  - Turner, C. D., C. R. Shea, and P. M. Rosoff. “Basal cell carcinoma originating from a nevus sebaceus on the scalp of a 7-year-old boy..” Journal of Pediatric Hematology/Oncology 23, no. 4 (May 2001): 247–49. https://doi.org/10.1097/00043426-200105000-00014.
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  - McGregor, L. M., and P. M. Rosoff. “Follicle-derived thyroid cancer in young people: the Duke experience..” Pediatric Hematology and Oncology 18, no. 2 (March 2001): 89–100. https://doi.org/10.1080/088800101300002919.
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  - Rosoff, P. M., and L. M. McGregor. “Papillary adenocarcinoma of the thyroid in a thyroglossal duct cyst..” Pediatric Hematology and Oncology 17, no. 7 (October 2000): 591–95. https://doi.org/10.1080/08880010050122861.
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  - Rosoff, P. M. “Assessing the risk of breast cancer..” The New England Journal of Medicine 342, no. 26 (June 2000). https://doi.org/10.1056/nejm200006293422618.
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  - Rosoff, P. M., S. Hatcher, and D. C. West. “Biphenotypic sarcoma with characteristics of both a Ewing sarcoma and a desmoplastic small round cell tumor..” Medical and Pediatric Oncology 34, no. 6 (June 2000): 407–12. https://doi.org/10.1002/(sici)1096-911x(200006)34:6<407::aid-mpo5>3.0.co;2-x.
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  - Rosoff, P. M., and S. Bayliff. “Successful clinical response to irinotecan in desmoplastic round blue cell tumor..” Medical and Pediatric Oncology 33, no. 5 (November 1999): 500–503. https://doi.org/10.1002/(sici)1096-911x(199911)33:5<500::aid-mpo12>3.0.co;2-x.
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  - Powell, J., T. Traweek, O. Beatty, M. B. Qumsiyeh, and P. M. Rosoff. “A novel chromosomal rearrangement associated with therapy-related acute leukemia..” Cancer Genetics and Cytogenetics 112, no. 2 (July 1999): 173–77. https://doi.org/10.1016/s0165-4608(98)00277-5.
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  - Warwick, A. B., K. Haver, and P. M. Rosoff. “Homozygous sickle cell disease and cystic fibrosis in an adolescent..” Pediatric Pulmonology 26, no. 3 (September 1998): 224–27. https://doi.org/10.1002/(sici)1099-0496(199809)26:3<224::aid-ppul11>3.0.co;2-2.
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  - Howrey, R. P., W. J. Lipham, W. H. Schultz, E. G. Buckley, J. J. Dutton, G. K. Klintworth, and P. M. Rosoff. “Sebaceous gland carcinoma: a subtle second malignancy following radiation therapy in patients with bilateral retinoblastoma..” Cancer 83, no. 4 (August 1998): 767–71. https://doi.org/10.1002/(sici)1097-0142(19980815)83:4<767::aid-cncr20>3.0.co;2-p.
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  - Castellino, S., T. Traweek, and P. M. Rosoff. “Ewing's tumor and papillary adenocarcinoma of the thyroid in a 14-year-old girl..” Journal of Pediatric Hematology/Oncology 20, no. 2 (March 1998): 177–80. https://doi.org/10.1097/00043426-199803000-00019.
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  - Trede, N. S., A. B. Warwick, P. M. Rosoff, R. Rohrer, B. E. Bierer, and E. Guinan. “Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation..” Bone Marrow Transplantation 20, no. 3 (August 1997): 257–60. https://doi.org/10.1038/sj.bmt.1700872.
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  - Wong, W. S., D. I. Simon, P. M. Rosoff, N. K. Rao, and H. A. Chapman. “Mechanisms of pertussis toxin-induced myelomonocytic cell adhesion: role of Mac-1(CD11b/CD18) and urokinase receptor (CD87)..” Immunology 88, no. 1 (May 1996): 90–97. https://doi.org/10.1046/j.1365-2567.1996.d01-646.x.
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  - Wong, W. S., and P. M. Rosoff. “Pharmacology of pertussis toxin B-oligomer..” Canadian Journal of Physiology and Pharmacology 74, no. 5 (May 1996): 559–64. https://doi.org/10.1139/cjpp-74-5-559.
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  - Rosoff, P. M. “Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase..” The Journal of Pediatrics 127, no. 4 (October 1995): 605–8. https://doi.org/10.1016/s0022-3476(95)70124-9.
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  - Zhang, X. M., R. Berland, and P. M. Rosoff. “Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor..” Molecular Immunology 32, no. 5 (April 1995): 323–32. https://doi.org/10.1016/0161-5890(94)00160-3.
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  - WONG, W. S. F., N. K. RAO, D. I. SIMON, P. M. ROSOFF, and H. A. CHAPMAN. “PERTUSSIS TOXIN (PTX) STIMULATES MYELOID CELL-ADHESION TO VITRONECTIN (VN) - FUNCTIONAL-LINK BETWEEN MAC-1 (CD11B/CD18) THE UROKINASE RECEPTOR (CD87).” Faseb Journal 9, no. 4 (March 10, 1995): A797–A797.
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  - Rosoff, P. M. “Congenital bone marrow failure with myelodysplasia in siblings..” Journal of Pediatric Hematology/Oncology 17, no. 1 (February 1995): 56–60.
  - ROSOFF, P. M. “Congenital bone marrow failure with myelodysplasia in siblings.” J Pediatr Hematol Oncol 17 (1995): 56–60. https://doi.org/10.1097/00043426-199502000-00010.
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  - CIFUENTES, M. E., R. S. MITTLER, and P. M. ROSOFF. “THE CD45 TYROSINE PROTEIN-KINASE IS NOT REQUIRED FOR SIGNALING AND ACTIVATION OF HUMAN T-LYMPHOCYTES BY THE PERTUSSIS TOXIN RECEPTOR.” Blood 84, no. 10 (November 15, 1994): A285–A285.
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  - ROSOFF, P. M. “CHARACTERIZATION OF A NOVEL ECTO-ADP-RIBOSYL-TRANSFERASE IN T-LYMPHOCYTES BY THE B-SUBUNIT OF PERTUSSIS TOXIN.” Blood 84, no. 10 (November 15, 1994): A432–A432.
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  - ZHANG, X. M., R. BERLAND, and P. M. ROSOFF. “THE CD3-T CELL ANTIGEN RECEPTOR COMPLEX REGULATES PERTUSSIS TOXIN RECEPTOR-STIMULATED TYROSINE PROTEIN-PHOSPHORYLATION.” Blood 82, no. 10 (November 15, 1993): A246–A246.
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  - MASCHEK, B. J., W. ZHANG, P. M. ROSOFF, and H. REISER. “MODULATION OF THE INTRACELLULAR CA2+ AND INOSITOL TRISPHOSPHATE CONCENTRATIONS IN MURINE-T LYMPHOCYTES BY THE GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED PROTEIN SGP-60.” Journal of Immunology 150, no. 8 (April 15, 1993): 3198–3206.
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  - Maschek, B. J., W. Zhang, P. M. Rosoff, and H. Reiser. “Modulation of the intracellular Ca2+ and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol-anchored protein sgp-60..” Journal of Immunology (Baltimore, Md. : 1950) 150, no. 8 Pt 1 (April 1993): 3198–3206.
  - O’Riordan, C., and P. M. Rosoff. “Reconstitution of a T cell receptor-stimulated plasma membrane calcium transporter: lack of dependence on inositol phosphates..” Cell Calcium 14, no. 2 (February 1993): 119–33. https://doi.org/10.1016/0143-4160(93)90082-h.
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  - Maschek, B. J., W. Zhang, P. M. Rosoff, and H. Reiser. “Modulation of the intracellular Ca²⁺ and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol- anchored protein sgp-60.” Journal of Immunology 150, no. 8 I (January 1, 1993): 3198–3206.
  - Prasad, K. R., and P. M. Rosoff. “Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae..” Cell Calcium 13, no. 10 (November 1992): 615–26. https://doi.org/10.1016/0143-4160(92)90072-z.
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  - Rosoff, P. M., and C. Mohan. “Unidirectional, heterologous desensitization of the pertussis toxin receptor by the CD3/TCR complex..” Journal of Immunology (Baltimore, Md. : 1950) 149, no. 10 (November 1992): 3191–99.
  - Corey, S. J., and P. M. Rosoff. “Unsaturated fatty acids and lipoxygenase products regulate phagocytic NADPH oxidase activity by a nondetergent mechanism..” The Journal of Laboratory and Clinical Medicine 118, no. 4 (October 1991): 343–51.
  - Rogers, T. S., S. J. Corey, and P. M. Rosoff. “Identification of a 43-kilodalton human T lymphocyte membrane protein as a receptor for pertussis toxin..” Journal of Immunology (Baltimore, Md. : 1950) 145, no. 2 (July 1990): 678–83.
  - Dinarello, C. A., B. D. Clark, T. Ikejima, A. J. Puren, N. Savage, and P. M. Rosoff. “Interleukin 1 receptors and biological responses..” The Yale Journal of Biology and Medicine 63, no. 2 (March 1990): 87–93.
  - Rosoff, P. M. “IL-1 receptors: structure and signals..” Seminars in Immunology 2, no. 2 (March 1990): 129–37.
  - Corey, S. J., and P. M. Rosoff. “Granulocyte-macrophage colony-stimulating factor primes neutrophils by activating a pertussis toxin-sensitive G protein not associated with phosphatidylinositol turnover..” The Journal of Biological Chemistry 264, no. 24 (August 1989): 14165–71.
  - Dinarello, C. A., B. D. Clark, A. J. Puren, N. Savage, and P. M. Rosoff. “The interleukin 1 receptor..” Immunology Today 10, no. 2 (February 1989): 49–51. https://doi.org/10.1016/0167-5699(89)90304-6.
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  - Melton, L. B., F. Lakkis, M. Moscovitch-Lopatin, B. R. Smith, J. M. Williams, P. M. Rosoff, and T. B. Strom. “Antibody valence and induced signal transduction: the role of antibody valence in anti-CD3-induced signal transduction in isolated normal T cells..” Clinical Immunology and Immunopathology 50, no. 2 (February 1989): 171–83. https://doi.org/10.1016/0090-1229(89)90126-8.
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  - Dinarello, C. A., B. D. Clark, A. J. Puren, N. Savage, and P. M. Rosoff. “The interleukin 1 receptor.” Immunology Today 10, no. 2 (January 1, 1989): 49–51. https://doi.org/10.1016/0167-5699(89)90304-6.
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  - Rosoff, P. M. “Characterization of the interleukin-1-stimulated phospholipase C activity in human T lymphocytes..” Lymphokine Research 8, no. 4 (January 1989): 407–13.
  - Rosoff, P. M., C. Hall, L. S. Gramates, and S. R. Terlecky. “4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid inhibits CD3-T cell antigen receptor-stimulated Ca2+ influx in human T lymphocytes..” The Journal of Biological Chemistry 263, no. 36 (December 1988): 19535–40.
  - Rosoff, P. M., N. Savage, and C. A. Dinarello. “Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism..” Cell 54, no. 1 (July 1988): 73–81. https://doi.org/10.1016/0092-8674(88)90181-x.
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  - Rosoff, P. M., R. Walker, and L. Winberry. “Pertussis toxin triggers rapid second messenger production in human T lymphocytes..” Journal of Immunology (Baltimore, Md. : 1950) 139, no. 7 (October 1987): 2419–23.
  - Rosoff, P. M., S. J. Burakoff, and J. L. Greenstein. “The role of the L3T4 molecule in mitogen and antigen-activated signal transduction..” Cell 49, no. 6 (June 1987): 845–53. https://doi.org/10.1016/0092-8674(87)90622-2.
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  - Rosoff, P. M., and G. Terres. “Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells..” J Cell Biol 103, no. 2 (August 1986): 457–63. https://doi.org/10.1083/jcb.103.2.457.
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  - ROSOFF, P. M., and C. M. HALL. “RECONSTITUTION OF THE T3-T CELL ANTIGEN RECEPTOR COMPLEX ACTIVATED CA-2+ TRANSPORTER FROM HUMAN T-CELLS.” Journal of Cellular Biochemistry, January 1, 1986, 203–203.
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  - ROSOFF, P. M., and L. C. CANTLEY. “LYMPHOCYTE-B DIFFERENTIATION - ROLE OF PHOSPHOINOSITIDES, C KINASE, AND NA+-H+ EXCHANGE.” Current Topics in Membranes and Transport 26 (January 1, 1986): 193–99.
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  - Rosoff, P. M., and G. Terres. “Cyclosporine A inhibits Ca²⁺-dependent stimulation of the Na⁺/H⁺ antiport in human T cells.” Journal of Cell Biology 103, no. 2 (1986): 457–63.
  - Rosoff, P. M., and L. C. Cantley. “B Lymphocyte Differentiation: Role of Phosphoinositides, C Kinase, and Na⁺-H⁺ Exchange.” Current Topics in Membranes and Transport 26, no. C (January 1, 1986): 193–99. https://doi.org/10.1016/S0070-2161(08)60733-9.
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  - Rosoff, P. M., and L. C. Cantley. “Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line..” The Journal of Biological Chemistry 260, no. 26 (November 1985): 14053–59.
  - Rosoff, P. M., and L. C. Cantley. “Lipopolysaccharide and phorbol esters induce differentiation but have opposite effects on phosphatidylinositol turnover and Ca2+ mobilization in 70Z/3 pre-B lymphocytes..” The Journal of Biological Chemistry 260, no. 16 (August 1985): 9209–15.
  - Oettgen, H. C., C. Terhorst, L. C. Cantley, and P. M. Rosoff. “Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx..” Cell 40, no. 3 (March 1985): 583–90. https://doi.org/10.1016/0092-8674(85)90206-5.
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  - ROSOFF, P. M. “Lipopolysaccharide and phorbol esters induce differentiation but have opposite effects on phosphatidylinositol turnover and Ca^<2+> mobilization in 70Z/3 pre-B lymphocytes.” J Biol Chem 260 (1985): 9209–15.
  - ROSOFF, P. M., and L. C. CANTLEY. “STIMULATION OF THE T3-T CELL RECEPTOR-ASSOCIATED CA-2+ INFLUX ENHANCES THE ACTIVITY OF THE NA+/H+ EXCHANGER IN A LEUKEMIC HUMAN T-CELL LINE.” Journal of Biological Chemistry 260, no. 26 (January 1, 1985): 4053–59.
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  - Rosoff, P. M., and L. C. Cantley. “Ion fluxes and differentiation in transformed cell lines..” Society of General Physiologists Series 39 (January 1985): 193–204.
  - Rosoff, P. M., and L. C. Cantley. “The role of ion fluxes in hematopoietic cell differentiation..” Progress in Clinical and Biological Research 184 (January 1985): 331–39.
  - Rosoff, P. M., L. F. Stein, and L. C. Cantley. “Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange..” The Journal of Biological Chemistry 259, no. 11 (June 1984): 7056–60.
  - Cantley, L. C., and P. M. Rosoff. “Regulation of surface IgM expression: Role of plasma membrane Na⁺/H⁺exchange.” Federation Proceedings 43, no. 6 (January 1, 1984).
  - ROSOFF, P. M. “CORRECTION.” Proceedings of the National Academy of Sciences of the United States of America Biological Sciences 81, no. 8 (January 1, 1984): 2586–2586.
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  - Rosoff, P. M., and L. C. Cantley. “Increasing the intracellular Na+ concentration induces differentiation in a pre-B lymphocyte cell line..” Proceedings of the National Academy of Sciences of the United States of America 80, no. 24 (December 1983): 7547–50. https://doi.org/10.1073/pnas.80.24.7547.
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  - Newburger, P. E., J. M. Robinson, K. B. Pryzwansky, P. M. Rosoff, J. S. Greenberger, and A. I. Tauber. “Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst..” Blood 61, no. 6 (June 1983): 1247–57.
  - ROSOFF, P. M., and L. C. CANTLEY. “INCREASING CELLULAR NA+ INDUCES DIFFERENTIATION IN A PRE-B LYMPHOCYTE CELL-LINE.” Journal of General Physiology 82, no. 6 (January 1, 1983): A30–A30.
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  - Rosoff, P. M., and L. C. Cantley. “Increasing the intracellular Na⁺ concentration induces differentiation in a pre-B lymphocyte cell line.” Proceedings of the National Academy of Sciences of the United States of America 80, no. 24 I (January 1, 1983): 7547–50. https://doi.org/10.1073/pnas.80.24.7547.
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  - Rosoff, P. M. “Fair healthcare rationing and the sorites paradox.” Journal of Medicine and Philosophy in press (n.d.): inpress-inpress.
- Conference Papers
  - Demark-Wahnefried, W., C. Werner, E. C. Clipp, A. B. Guill, M. Bonner, and P. M. Rosoff. “Childhood cancer survivors: Health behaviors and receptivity to health promotion interventions..” In Cancer Epidemiology Biomarkers & Prevention, 13:1939S-1939S. AMER ASSOC CANCER RESEARCH, 2004.
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Teaching & Mentoring
Recent Courses
- BIOETHIC 603S: Clinical Bioethics and Health Policy 2018
Advising & Mentoring
- I would be pleased to serve as a faculty mentor to students (undergrad, grad) or post-degree professionals (post-doc, fellow, junior faculty), especially those who wish advice, supervision or collaboration on their scholarly research projects.
Available to mentor:
- Affiliate
- Faculty
- Masters
- PhD
- Post-Doc
- Resident
- Undergraduate
Scholarly, Clinical, & Service Activities
Outreach & Engaged Scholarship
- Bass Connections Faculty Team Member. Expressive Writing for Resilience in Adult Pediatric Oncology Survivors and Their Caregivers. 2018 - 2019 2018 - 2019

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Advising & Mentoring

Available to mentor:

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