Research Interests
Liver Related Projects:
- Mechanisms of hepatic lipogenesis and gluconeogenesis.
- Determinants of NAFLD status in Bariatric Surgery Patients.
- Defining the impact of heart failure on liver metabolism.
Heart Related Projects:
- Metabolic determinants of cardiac function.
- Role of hepatic metabolic alterations in heart failure pathogenesis.
- Functional significance of acylcarnitine associations with cardiac outcomes.
Selected Grants
Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029Nonalcoholic Fatty Liver Disease (NAFLD) in Polycystic Ovary Syndrome: The Role of Androgens on Visceral Fat, Lipid Metabolites, and Liver Injury in Young Women
ResearchCo Investigator · Awarded by University of California - San Francisco · 2023 - 2028Mechanisms linking the Branched-Chain alpha-Keto Acid regulatory network to the pathogenesis of NASH
ResearchPrincipal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2023 - 2028Mechanisms Connecting Dysregulated Branched-Chain Alpha-Ketoacid Metabolism to Cardiac Dysfunction
ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027Leveraging glucagon activity to target hepatic steatosis, fibrosis, and inflammation
ResearchCo Investigator · Awarded by Merck Sharp & Dohme · 2022 - 2025Quantifying Enteric Metabolism of Branched-chain Amino Acids in Relation to Other Dietary and Microbiota Nutrients
ResearchCo-Mentor · Awarded by National Institutes of Health · 2022 - 2023Mechanisms connecting dysregulated BCAA, glucose & lipid metabolism in the pathogenesis of metabolic disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2019 - 2023A New Homeostatic Mechanism for Metabolic Control
ResearchPrincipal Investigator · Awarded by American Diabetes Association · 2016 - 2022Reshaping Liver Branched-Chain Alpha-Keto Acid Metabolism to Prevent Diabetic Cardiomyopathy
FellowshipPrincipal Investigator · Awarded by American Diabetes Association · 2021 - 2022Collaborative Study on Biomarkers of Fatty Liver Diseases
ResearchInvestigator · Awarded by Pfizer, Inc. · 2017 - 2018Manipulation of BCAA Metabolism for Therapy of Diabetes and its Co-morbidities
ResearchCo-Principal Investigator · Awarded by Eli Lilly and Company · 2017 - 2018External Relationships
- xwpharma
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.