Scholars@Duke
Claude Anthony Piantadosi

Claude Anthony Piantadosi

Professor Emeritus of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
piant001@mc.duke.edu
Duke Box 3315, Durham, NC 27710
0570 Clin Res II, Durham, NC 27710

Selected Grants

Characterization of CMV-specific T cell responses in immunocompromised hosts

ResearchCo-Mentor · Awarded by National Institutes of Health · 2022 - 2024

Mitochondrial quality control and alveolar damage resolution after acute lung injury

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2022

Oxidative tissue damage mitigation after exposure to HBO2 using FDA approved anti-epileptic drugs (AEDs)

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2018 - 2022

IPA - Linhua Song

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2020 - 2022

Role of S-nitrosothiols on Akt1 signaling and pneumonia resolution

ResearchMentor · Awarded by National Institutes of Health · 2017 - 2021

Interdisciplinary Training Program in Lung Disease

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2021

Interface of Mitochondrial Quality Control and Immune Activation in Heart Transplant

ResearchMentor · Awarded by Foundation for Anesthesia Education and Research · 2018 - 2020

The role of Pdgfra+ fibroblasts in lung fibrosis and alveolar homeostasis

ResearchAdvisor · Awarded by National Institutes of Health · 2014 - 2019

Novel Dialysis-Like Therapeutics in Sepsis-induced Shock and Organ Failure

ResearchCo Investigator · Awarded by Defense Advanced Research Projects Agency · 2015 - 2018

Noncanonical Receptor Signaling in Pulmonary Arterial Hypertension

ResearchConsultant · Awarded by National Institutes of Health · 2013 - 2018

Redox Regulation of Lung Mitochondrial Biogenesis in Sepsis/Pneumonia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2017

Project 2: Regulation of Mitochondrial Quality Control by Heme Oxygenase-1 System in Sepsis

ResearchPrincipal Investigator · Awarded by Brigham and Women's Hospital · 2011 - 2017

The Duke Multidisciplinary Training Program in Pediatric Lung Disease

Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2010 - 2016

The Role of Tfam in Mitochondrial Biogenesis following sepsis

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2015

Ozone Primes Pulmonary Innate Immunity

ResearchConsultant · Awarded by National Institutes of Health · 2008 - 2015

Nitric oxide and mitochondrial biogenesis in sepsis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2014

Peripheral endothelial and muscle cell pathology in cardiovascular disease

ResearchConsultant · Awarded by National Institutes of Health · 2010 - 2013

Regulation of Rho Signaling by S-Nitrosothiols

ResearchCollaborator · Awarded by National Institutes of Health · 2009 - 2013

Regulation of mitochondrial biogenesis by heme oxygenase-1

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2013

Innate Immune Mechanisms in Non-infectious Lung Inflammation

ResearchConsultant · Awarded by National Institutes of Health · 2002 - 2013

Particle-Associated Lung Injury in Mice With and Without Expression of Neutrophil Elastase and nrf 2

ResearchPrincipal Investigator · Awarded by Environmental Protection Agency · 2012 - 2013

Mitochondrial biogenesis in sepsis-induced organ dysfunction

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2009 - 2013

IPA - John Patterson

ResearchPrincipal Investigator · Awarded by Durham Veterans Affairs Medical Center · 2012 - 2012

Clinical Centers for a Clinical Research Network for the Treatment of Acute Lung Injury and Adult Respiratory Distress Syndrome

Clinical TrialCollaborator · Awarded by National Institutes of Health · 2005 - 2011

Mechanisms of Intracellular Iron Accumulation in Cystic Fibrosis

ResearchMentor · Awarded by National Institutes of Health · 2006 - 2011

Neurogenic Mechanisms in CNS and Pulmonary Oxygen Toxicity

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2003 - 2010

Lung Injury Protection by Coagulation Blockade

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2010

Red Blood Cell S-nitrosothiols and Oxygenation

ResearchCollaborator · Awarded by National Institutes of Health · 2009 - 2009

Interdisciplinary Training Program in Lung Disease

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1982 - 2009

Innate Immune Response to Environmental Endotoxin

ResearchMentor · Awarded by National Institutes of Health · 2004 - 2009

IPA - Hagir Suliman

ResearchPrincipal Investigator · Awarded by Veterans Administration Medical Center · 2006 - 2008

Nitric Oxide and CNS-Pulmonary Interactions in 02 Toxicity

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2003 - 2007

Toxic and Therapeutic Effects of Oxygen

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1990 - 2007

Mechanisms of PM Induced Pulmonary Injury in Genetically Altered Mice

ResearchPrincipal Investigator · Awarded by Environmental Protection Agency · 2005 - 2006

Leukocyte Chemokine Blockade to Preserve LungDevelopment

ResearchConsultant · Awarded by National Institutes of Health · 2002 - 2006

Mechanisms Causing Pulmonary Xenograft Injury

ResearchConsultant · Awarded by National Institutes of Health · 1998 - 2006

Regulation of Mucin Gene Expression by Elastase

ResearchConsultant · Awarded by National Institutes of Health · 2000 - 2005

Interdisciplinary Training program in lung disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1982 - 2002

same

Institutional SupportPrincipal Investigator · Awarded by National Institutes of Health · 1982 - 2002

Interdisciplinary Training Program In Lung Disease

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 1982 - 2002

Biological Effects of Particle Exposure

ResearchPrincipal Investigator · Awarded by Environmental Protection Agency · 2001 - 2002

Particle Exposure and Acute Lung Injury

ResearchPrincipal Investigator · Awarded by Environmental Protection Agency · 2000 - 2001

Toxic And Therapeutic Effects Of Oxygen

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1990 - 1999

Acute Lung Injury Mechanisms And Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1984 - 1999

Toxic And Therapeutic Effects Of Hyperbaric Oxygen

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1990 - 1995

Acute Lung Injury And Repair

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1995