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Pei Zhong

Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
Thomas Lord Department of Mechanical Engineering and Materials Science
1103 Engineering Annex, Box 90300, Durham, NC 27708-0300
1103 Engineering Annex, Box 90300, Durham, NC 27708

Overview


My research focuses on engineering and technology development with applications in the non-invasive or minimally invasive treatment of kidney stone disease via shock wave and laser lithotripsy, high-intensity focused ultrasound (HIFU) and immunotherapy for cancer treatment, acoustic and optical cavitation, and ultrasound neuromodulation via sonogenetics. 

We are taking an integrated and translational approach that combines fundamental research with engineering and applied technology development to devise novel and enabling ultrasonic, optical, and mechanical tools for a variety of clinical applications. We are interested in shock wave/laser-fluid-bubble-solid interaction, and resultant mechanical and thermal fields that lead to material damage and removal.  We also investigate the stress response of biological cell and tissue induced by cavitation and ultrasound exposure, mediated through mechanosensitive ion channels, such as Piezo 1. Our research activities are primarily supported by NIH and through collaborations with the medical device industry.

Current Appointments & Affiliations


Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science · 2012 - Present Thomas Lord Department of Mechanical Engineering and Materials Science, Pratt School of Engineering

Education, Training & Certifications


University of Texas, Arlington · 1992 Ph.D.
University of Texas Southwestern Medical Center, Medical School · 1988 M.Sc.