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RAJESHKUMAR MANNE

Research Associate, Senior
Pathology
210 Research Drive, GSRB-II, Room 4009, Durham, NC 27710
210 Research Drive, GSRB-II, Room 4035, Durham, NC 27710

Current Appointments & Affiliations


Research Associate, Senior Pathology, Clinical Science Departments

Recent Publications


IMPA1-derived inositol maintains stemness in castration-resistant prostate cancer via IMPDH2 activation.

Journal Article J Exp Med · November 4, 2024 Acquisition of prostate cancer stem cells (PCSCs) manifested during androgen ablation therapy (ABT) contributes to castration-resistant prostate cancer (CRPC). However, little is known about the specific metabolites critically orchestrating this process. H ... Full text Link to item Cite

AMPK: The energy sensor at the crossroads of aging and cancer.

Journal Article Seminars in cancer biology · November 2024 AMP-activated protein kinase (AMPK) is a protein kinase that plays versatile roles in response to a variety of physiological stresses, including glucose deprivation, hypoxia, and ischemia. As a kinase with pleiotropic functions, it plays a complex role in ... Full text Cite
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Recent Grants


Unravel a novel metabolic pathway orchestrating prostate cancer progression and therapeutic resistance

ResearchResearch Associate · Awarded by National Cancer Institute · 2023 - 2027

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