Overview
Outcome-based research on pathology of endometrial carcinoma, including prognostic significance of histologic features of endometrial carcinoma, variants of endometrial carcinoma, definitions of atypia and well-differentiated carcinoma, and collaborative studies of oncogenes and tumor suppressor genes in endometrial carcinoma.
Endometrial pathology, especially as it relates to molecular/genetic alterations in neoplasms.
Ovarian pathology, especially as it relates to molecular and genetic alterations in neoplasms.
Improving accuracy of radiographic screening for breast cancer, by careful patho-radiographic correlation and study of improved imaging techniques (especially ultrasound).
Use of electron microscopy as a diagnostic and research technique.
Objective measures of pathology resident performance.
Endometrial pathology, especially as it relates to molecular/genetic alterations in neoplasms.
Ovarian pathology, especially as it relates to molecular and genetic alterations in neoplasms.
Improving accuracy of radiographic screening for breast cancer, by careful patho-radiographic correlation and study of improved imaging techniques (especially ultrasound).
Use of electron microscopy as a diagnostic and research technique.
Objective measures of pathology resident performance.
Current Appointments & Affiliations
Professor of Pathology
·
2012 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
1986 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Standardized Pathologic Reporting for Phyllodes Tumors: Where are We after 3 Years?
Journal Article Ann Surg Oncol · February 2026 Full text Link to item CiteAutomation of fluorescent in situ hybridization (FISH) leading to cost savings and consistent high-quality results.
Journal Article J Clin Pathol · January 19, 2026 AIMS: Despite continually improving guidelines, human epidermal growth factor receptor 2 (HER2) testing for breast and gastro-oesophageal carcinoma continues to be a technical challenge in clinical laboratories. Manual HER2 fluorescence in situ hybridisati ... Full text Link to item CiteSupplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States
Other · November 26, 2025 Supplementary Table from Extended Human Papillomavirus Genotyping to Predict Progression to High-Grade Cervical Precancer: A Prospective Cohort Study in the Southeastern United States ... Full text CiteRecent Grants
Validation of UM1 candidate targets in fusion-positive rhabdomyosarcoma preclinical models
ResearchCollaborator · Awarded by Massachusetts Institute of Technology · 2024 - 2029Identification of Oncofusion-Interacting Proteins as Essential Drug Targets for Common and Rare Oncofusions in Rhabdomyosarcoma
ResearchCollaborator · Awarded by Department of Defense · 2025 - 2028ZEB2 as a cell fate switch in fusion-positive rhabdomyosarcoma
ResearchCollaborator · Awarded by Hyundai Hope on Wheels · 2024 - 2026View All Grants
Education
Harvard University ·
1986
M.D.