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Richard Barfield

Biostatistician, Senior
Biostatistics & Bioinformatics
Duke Box 2721, Durham, NC 27710
2424 Erwin Road Suite 1106, 11028A Hock Plaza, Durham, NC 27705

Overview


Richard received his PhD from Harvard University in 2017 and his MPH from Emory University in 2012. He is currently working with researchers within the Duke Center for Human Systems Immunology and Center for Aids Research. His past research was working with DNA methylation microarray data and methods development for summary Mendelian Randomization studies. He works closely with investigators to answer research questions related to the immune system or HIV/AIDS.

Current Appointments & Affiliations


Recent Publications


Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV.

Journal Article JCI Insight · March 22, 2023 Rhesus cytomegalovirus-based (RhCMV-based) vaccine vectors induce immune responses that protect ~60% of rhesus macaques (RMs) from SIVmac239 challenge. This efficacy depends on induction of effector memory-based (EM-biased) CD8+ T cells recognizing SIV pep ... Full text Link to item Cite

Association between germline variants and somatic mutations in colorectal cancer.

Journal Article Scientific reports · June 2022 Colorectal cancer (CRC) is a heterogeneous disease with evidence of distinct tumor types that develop through different somatically altered pathways. To better understand the impact of the host genome on somatically mutated genes and pathways, we assessed ... Full text Cite

HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth.

Journal Article Sci Rep · July 14, 2021 A major challenge in developing an effective vaccine against HIV-1 is the genetic diversity of its viral envelope. Because of the broad range of sequences exhibited by HIV-1 strains, protective antibodies must be able to bind and neutralize a widely mutate ... Full text Link to item Cite
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Recent Grants


Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology

ResearchStatistician · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

Immunologic and Virologic Determinants of Congenital Cytomegalovirus Transmission and Disease in Rhesus Monkeys

ResearchBiostatistician · Awarded by Weill Cornell Medicine · 2020 - 2029

Quantitative Methods for HIV/AIDS Research

Inst. Training Prgm or CMEBiostatistician · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028

View All Grants