Research Interests
- Clinical trials in heart failure
- Co-morbidity characterization (diabetes, lung disease, sleep apnea, renal failure) in heart failure.
- Phenotypic characterization and risk prognostication of patients with heart failure.
- Role of surrogate and nonfatal endpoints (e.g., dyspnea) in clinical heart failure trials.
- Biomarkers in heart failure.
- Novel pharmacological and non-pharmacological approaches to heart failure.
- Improving site-based heart failure research.
Selected Grants
Research Triangle Center of Excellence in Regulatory Science and Innovation
ResearchCo-Principal Investigator · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028BalanceD-HF
Clinical TrialPrincipal Investigator · Awarded by AstraZeneca UK Limited · 2024 - 2027Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial - Trial Administration
ResearchPrincipal Investigator · Awarded by Wake Forest University Health Sciences · 2022 - 2027UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2016 - 2026Journal of Cardiac Failure
Public ServicePrincipal Investigator · Awarded by Heart Failure Society of America · 2021 - 2025The optimal loop diuretic: mechanistic insights from longitudinal changes in blood and urine proteins to explain efficacy and safety of torsemide vs furosemide after a heart failure hospitalization
ResearchPrincipal Investigator · Awarded by Inova Health System · 2020 - 2025Development and Validation of Advanced Heart Failure Computable Phenotypes
ResearchPrincipal Investigator · Awarded by Mayo Clinic - Rochester · 2023 - 2025Postdoctoral Training in Cardiovascular Clinical Research
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2003 - 2025Exscel Biomarker Analysis and Secondary Manuscript Production
Clinical TrialPrincipal Investigator · Awarded by AstraZeneca Pharmaceuticals, LP · 2020 - 2024PROSPective evaluation of Eggland's Best Related to Improvement in The biomarker profile for Your health
Clinical TrialPrincipal Investigator · Awarded by Eggland's Best, LLC · 2020 - 2024Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage
ResearchCo Investigator · Awarded by University of Mississippi Medical Center · 2022 - 2023Health Economics and Outcomes Research Collaboration
ResearchPrincipal Investigator · Awarded by Cytokinetics, Inc. · 2020 - 2023New Advances in HFrEF: Learning Lab
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Cytokinetics, Inc. · 2022 - 2023Evaluating Population-Level Disparities in Cardiovascular Disease Progression: A Structural Equation Modeling Approach
FellowshipPrincipal Investigator · Awarded by American Heart Association · 2022 - 2022Prognostic value of Heart Rate Variability measured by Cardiovascular Implantable Electronic Devices
ResearchPrincipal Investigator · Awarded by Bayer Pharmaceuticals · 2020 - 2022VICTORIA Registry
ResearchPrincipal Investigator · Awarded by Merck · 2017 - 2022Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage
ResearchCo Investigator · Awarded by University of Mississippi Medical Center · 2021 - 2022Development and Validation of Advanced Heart Failure Computable Phenotypes
ResearchPrincipal Investigator · Awarded by Mayo Clinic - Rochester · 2022 - 2022TRANSFORM-HF CCC
Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2017 - 2022BAY 2413555 in pts w HF and ICD
ResearchPrincipal Investigator · Awarded by Bayer HealthCare AG · 2021 - 2022Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage
ResearchCo Investigator · Awarded by University of Mississippi Medical Center · 2020 - 2021UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2020 - 2021Target-HF-CM
Clinical TrialPrincipal Investigator · Awarded by American Heart Association · 2017 - 2021REHAB: A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients
Clinical TrialPrincipal Investigator · Awarded by Wake Forest University Health Sciences · 2014 - 2021JTT-251_HF Trial
Clinical TrialPrincipal Investigator · Awarded by Akros Medical · 2017 - 2020Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage
ResearchCo Investigator · Awarded by University of Mississippi Medical Center · 2019 - 2020PROVIDE-HF: Patient Reported Outcomes inVestigation following Initiation of Drug therapy with Entresto (Valsartan/Sacubitril) in Heart Failure.
Clinical TrialPrincipal Investigator · Awarded by Novartis Pharmaceuticals Corporation · 2017 - 2020Comparison of Dyspnea Measurement Instruments in Acute Heart Failure
Clinical TrialSenior Investigator · Awarded by Heart Failure Society of America · 2017 - 2019Depression and Heart Failure Disease Progression
ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2019Accrelerometry Substudy
ResearchPrincipal Investigator · Awarded by Wake Forest University Health Sciences · 2017 - 2019Define-HF
Clinical TrialPrincipal Investigator · Awarded by Saint Luke's Hospital (Kansas City) · 2016 - 2019Subcutaneous Furosemide in Acute Decompensated Heart Failure
Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2018Sub Q
Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018Characterizing HIV-related Diastolic Dysfunction
Clinical TrialPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 2016 - 2018Accelerometer Data Collection and Analysis of REHAB-HF Participants
Clinical TrialPrincipal Investigator · Awarded by Wake Forest University Health Sciences · 2015 - 2018A Collaboration for Improving Outcomes of African Americans with Heart Failure
ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2018Angina Pectoris in Diabetic Patients
ResearchPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2014 - 2018Cardiac Outcomes Risk Assessment (CORA)
ResearchCo Investigator · Awarded by Carnegie Mellon University · 2015 - 2017Palliative Care in Heart Failure (PAL-HF)
Clinical TrialResearch Assistant · Awarded by National Institutes of Health · 2011 - 2016Cardiovascular Improvements with Minute Ventilation-targeted ASV Therapy in Heart Failure
Clinical TrialPrincipal Investigator · Awarded by ResMed Corp · 2013 - 2016External Relationships
- Abbott (St. Jude Medical)
- Alleviant Medical
- Amgen
- AstraZeneca
- Bayer
- Boehringer Ingleheim
- Lilly
- Medtronic (Covidien)
- Merck
- Novartis
- Novo Nordisk
- Pharmacosmos
- Respicardia
- Rocket Pharma
- Windtree Therapeutics, Inc.
- american regent
- innolife
- vifor
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.