Robert Ellis Reiman Jr. | Scholars@Duke

Robert Ellis Reiman Jr.
Associate Professor of Radiology

Dr. Reiman is diplomate of the American Board of Nuclear Medicine, and is the Associate Director the Radiation Safety Division of Duke's Occupational and Environmental Safety Office. He is on the faculty the Department of Radiology and a member of the Faculty of the Duke Medical Physics Graduate Program. He coordinates the patient care activities of the Duke Radiation Safety Division and participates in the teaching of radiology residents, and cardiology fellows and medical students. His current research interests include internal radionuclide dosimetry and the application of Web-based systems to problems in radiation safety and dosimetry. He has also published on imaging of bone, brain and soft-tissue tumors with nitrogen-13 labeled amino acids.

Current Appointments & Affiliations

Associate Professor of Radiology, Radiology, Clinical Science Departments 2013

Contact Information

2223 Pratt St, Rm 123, Durham, NC 27705
Box 3155 Med Ctr, Durham, NC 27710
robert.reiman@duke.edu (919) 668-3186

Background
Education, Training, & Certifications
- M.D., Case Western Reserve University 1987
Duke Appointment History
- Assistant Professor of Radiology, Radiology, Clinical Science Departments 2006 - 2013
- Assistant Clinical Professor of Radiology, Radiology, Clinical Science Departments 1999 - 2006
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1995
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1989 - 1994
Expertise
Subject Headings
Research
Selected Grants
- Health Physics: Accelerator Health Physics; Reactor Health Physics awarded by U.S. Nuclear Regulatory Commission 2012 - 2014
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Development of Nuclear Safety Graduate Level Courses Including Radionuclide Therapy Training Modules and Radiation Prote awarded by U.S. Nuclear Regulatory Commission 2007 - 2011
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Kane, Ari, Matthew P. Thorpe, Michael A. Morse, Brandon A. Howard, Jorge D. Oldan, Jason Zhu, Terence Z. Wong, Neil A. Petry, Robert Reiman, and Salvador Borges-Neto. “Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 59, no. 11 (November 2018): 1708–13. https://doi.org/10.2967/jnumed.117.202150.
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  - Chin, Bennett B., Darryl McDougald, Douglas H. Weitzel, Thomas Hawk, Robert E. Reiman, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine..” Current Radiopharmaceuticals 10, no. 1 (January 2017): 41–50. https://doi.org/10.2174/1874471009666161230114954.
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  - Howard, Brandon A., Olga G. James, Jennifer M. Perkins, Robert A. Pagnanelli, Salvador Borges-Neto, and Robert E. Reiman. “A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance..” Sage Open Medical Case Reports 5 (January 2017). https://doi.org/10.1177/2050313X17745203.
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  - Chin, Bennett, Darryl McDougald, Douglas Weitzel, Thomas Hawk, Robert Reiman, Michael Zalutsky, and Ganesan Vaidyanathan. “Synthesis and preliminary evaluation of 5-[18F]fluoroleucine: a novel LAT1 substrate.” Journal of Nuclear Medicine 57 (May 1, 2016).
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  - Hoang, Jenny K., Robert E. Reiman, Giao B. Nguyen, Natalie Januzis, Bennett B. Chin, Carolyn Lowry, and Terry T. Yoshizumi. “Lifetime Attributable Risk of Cancer From Radiation Exposure During Parathyroid Imaging: Comparison of 4D CT and Parathyroid Scintigraphy..” Ajr. American Journal of Roentgenology 204, no. 5 (May 2015): W579–85. https://doi.org/10.2214/ajr.14.13278.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease"..” Circulation 131, no. 16 (April 2015): e419–20. https://doi.org/10.1161/CIRCULATIONAHA.114.013266.
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  - Johnson, J. N., C. P. Hornik, J. S. Li, D. K. Benjamin, T. T. Yoshizumi, R. E. Reiman, D. P. Frush, and K. D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease.” Circulation 130, no. 2 (July 8, 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry T. Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease..” Circulation 130, no. 2 (July 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
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  - Samei, Ehsan, Xiang Li, Baiyu Chen, and Robert Reiman. “The effect of dose heterogeneity on radiation risk in medical imaging..” Radiation Protection Dosimetry 155, no. 1 (June 2013): 42–58. https://doi.org/10.1093/rpd/ncs275.
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  - Reiman, Robert E. “Informed consent in human research: what to say and how to say it..” Health Physics 104, no. 2 Suppl 1 (February 2013): S17–22. https://doi.org/10.1097/hp.0b013e318271b4c9.
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  - Reiman, Robert E. “Informed Consent in Human Research: What to Say and How to Say It.” Health Physics 104, no. 2 (February 2013): S17–22. https://doi.org/10.1097/HP.0b013e318271b4c9.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Sara K. Pasquali, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cancer Risk Estimation from Cardiac Catheterization in Children with Heart Disease.” Circulation 126, no. 21 (November 20, 2012).
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  - Edwards, Ben E., and Robert E. Reiman. “Comparison of current and past surgical smoke control practices..” Aorn Journal 95, no. 3 (March 2012): 337–50. https://doi.org/10.1016/j.aorn.2011.07.019.
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  - Chin, Bennett B., Anita Hjelemand, Jeremy Rich, Haijing Song, Christopher Lascola, Robert Storms, Roger McLendon, et al. “Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression..” Current Radiopharmaceuticals 5, no. 1 (January 2012): 47–58.
  - Reiman, R. E. “Radiation protection of technologists and ancillary personnel,” December 1, 2011, 83–90. https://doi.org/10.1007/978-0-387-48902-5_8.
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  - Edwards, Ben E., and Robert E. Reiman. “Results of a survey on current surgical smoke control practices..” Aorn Journal 87, no. 4 (April 2008): 739–49. https://doi.org/10.1016/j.aorn.2007.11.001.
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  - Hurwitz, Lynne M., Robert E. Reiman, Terry T. Yoshizumi, Philip C. Goodman, Greta Toncheva, Giao Nguyen, and Carolyn Lowry. “Radiation dose from contemporary cardiothoracic multidetector CT protocols with an anthropomorphic female phantom: implications for cancer induction..” Radiology 245, no. 3 (December 2007): 742–50. https://doi.org/10.1148/radiol.2453062046.
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  - Hurwitz, Lynne M., Terry T. Yoshizumi, Robert E. Reiman, Erik K. Paulson, Donald P. Frush, Giao T. Nguyen, Greta I. Toncheva, and Philip C. Goodman. “Radiation dose to the female breast from 16-MDCT body protocols..” Ajr. American Journal of Roentgenology 186, no. 6 (June 2006): 1718–22. https://doi.org/10.2214/ajr.04.1917.
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  - Hurwitz, Lynne M., Terry Yoshizumi, Robert E. Reiman, Philip C. Goodman, Erik K. Paulson, Donald P. Frush, Greta Toncheva, Giao Nguyen, and Lottie Barnes. “Radiation dose to the fetus from body MDCT during early gestation..” Ajr. American Journal of Roentgenology 186, no. 3 (March 2006): 871–76. https://doi.org/10.2214/ajr.04.1915.
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  - Reiman, R. “TU‐B‐I‐611‐01: Releasing Nuclear Medicine Patients to the Public: Dose Computations and Discharge Instructions.” Medical Physics 32, no. 6 (January 1, 2005). https://doi.org/10.1118/1.1998328.
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  - DeGrado, Timothy R., Robert E. Reiman, David T. Price, Shuyan Wang, and R Edward Coleman. “Pharmacokinetics and radiation dosimetry of 18F-fluorocholine..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 43, no. 1 (January 2002): 92–96.
  - DeGrado, T. R., S. W. Baldwin, S. Wang, M. D. Orr, R. P. Liao, H. S. Friedman, R. Reiman, D. T. Price, and R. E. Coleman. “Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 42, no. 12 (December 2001): 1805–14.
  - Brown, M. T., R. E. Coleman, A. H. Friedman, H. S. Friedman, R. E. McLendon, R. Reiman, G. J. Felsberg, et al. “Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results..” Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 2, no. 6 (June 1996): 963–72.
  - Reiman, R. E., and J. K. Fetters. “Localization of technetium-99m-sestamibi in diffuse myelodysplastic processes..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 37, no. 3 (March 1996): 471–73.
  - King, S. C., R. J. Reiman, and L. R. Prosnitz. “Prognostic importance of restaging gallium scans following induction chemotherapy for advanced Hodgkin's disease..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 12, no. 2 (February 1994): 306–11. https://doi.org/10.1200/jco.1994.12.2.306.
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  - Schmall, B., P. S. Conti, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, R. S. Benua, S. D. Yeh, J. R. Dahl, R. Lee, and J. S. Laughlin. “Imaging studies of patients with malignant fibrous histiocytoma using C-11-alpha-aminoisobutyric acid (AIB)..” Clinical Nuclear Medicine 12, no. 1 (January 1987): 22–26.
  - Sordillo, P. P., R. S. Benua, A. S. Gelbard, J. Bading, R. E. Reiman, G. B. Magill, and J. S. Laughlin. “Imaging of human tumors and organs with N-13-labeled L-methionine..” American Journal of Physiologic Imaging 1, no. 4 (January 1986): 195–200.
  - Kurzweil, P. R., D. R. Miller, J. E. Freeman, R. E. Reiman, and K. Mayer. “Use of sodium chromate Cr51 in diagnosing childhood idiopathic pulmonary hemosiderosis..” American Journal of Diseases of Children (1960) 138, no. 8 (August 1984): 746–48.
  - Conti, P. S., B. Schmall, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, J. R. Dahl, J. K. Jacobsen, R. Lee, and M. B. Winstead. “Synthesis and purification of sodium [11C]benzoate for physiological and metabolic studies: evaluation in a tumor-bearing dog..” International Journal of Nuclear Medicine and Biology 11, no. 2 (January 1984): 179–83. https://doi.org/10.1016/0047-0740(84)90058-5.
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  - Warrell, R. P., S. J. Kempin, R. S. Benua, R. E. Reiman, and C. W. Young. “Intratumoral consumption of indium-111 labeled platelets in a patient with hemangiomatosis and intravascular coagulation (Kasabach-Merritt syndrome)..” Cancer 52, no. 12 (December 1983): 2256–60. https://doi.org/10.1002/1097-0142(19831215)52:12<2256::aid-cncr2820521216>3.0.co;2-9.
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  - Sordillo, P. P., R. E. Reiman, R. S. Benua, A. S. Gelbard, G. B. Magill, G. Rosen, and J. S. Laughlin. “Quantitative scanning of soft-tissue sarcomas with nitrogen-13-labeled L-glutamate..” Cancer Investigation 1, no. 5 (January 1983): 387–93. https://doi.org/10.3109/07357908309048507.
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  - Reiman, R. E., R. S. Benua, A. S. Gelbard, J. C. Allen, J. J. Vomero, and J. S. Laughlin. “Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 23, no. 8 (August 1982): 682–87.
  - Sordillo, P. P., R. E. Reiman, A. S. Gelbard, R. S. Benua, G. B. Magill, and J. S. Laughlin. “Scanning with L-(13 N) glutamate: Assessment of the response to chemotherapy of a patient with embryonal rhabdomyosarcoma..” American Journal of Clinical Oncology 5, no. 3 (June 1982): 285–89.
  - Reiman, R. E., G. Rosen, A. S. Gelbard, R. S. Benua, and J. S. Laughlin. “Imaging of primary Ewing sarcoma with 13N-L-glutamate..” Radiology 142, no. 2 (February 1982): 495–500. https://doi.org/10.1148/radiology.142.2.6119736.
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  - REIMAN, R. E. “DIAGNOSIS OF ALCOHOLIC CIRRHOSIS WITH THE RIGHT-TO-LEFT HEPATIC LOBE RATIO - CONCISE COMMUNICATION.” Journal of Nuclear Medicine 23, no. 1 (January 1, 1982): 80–80.
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  - Reiman, R. E. “Re:diagnosis of alcoholic cirrhosis with the right-to-left hepatic lobe ratio: concise communication..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 23, no. 1 (January 1982).
  - Reiman, R. E., A. G. Huvos, R. S. Benua, G. Rosen, A. S. Gelbard, and J. S. Laughlin. “Quotient imaging with N-13 L-glutamate in osteogenic sarcoma: correlation with tumor viability..” Cancer 48, no. 9 (November 1981): 1976–81. https://doi.org/10.1002/1097-0142(19811101)48:9<1976::aid-cncr2820480912>3.0.co;2-x.
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  - Digenis, G. A., S. H. Vincent, C. S. Kook, R. E. Reiman, G. A. Russ, and R. S. Tilbury. “Tissue distribution studies of [18F]haloperidol, [18F]-beta-(4-fluorobenzoyl)propionic acid, and [82Br]bromperidol by external scintigraphy..” Journal of Pharmaceutical Sciences 70, no. 9 (September 1981): 985–89. https://doi.org/10.1002/jps.2600700904.
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  - GELBARD, A. S., B. R. FREED, R. E. REIMAN, and A. J. L. COOPER. “N-13-LABELED L-AMINO-ACIDS - ENZYMATIC SYNTHESES AND METABOLIC STUDIES.” Advances in Chemistry Series, no. 197 (January 1, 1981): 389–403.
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  - Gelbard, A. S., R. S. Benua, R. E. Reiman, J. M. McDonald, J. J. Vomero, and J. S. Laughlin. “Imaging of the human heart after administration of L-(N-13)glutamate..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 21, no. 10 (October 1980): 988–91.
  - Hollocher, T. C., E. Garber, A. J. Cooper, and R. E. Reiman. “13N,15N isotope and kinetic evidence against hyponitrite as an intermediate in dentrification..” The Journal of Biological Chemistry 255, no. 11 (June 1980): 5027–30.
  - HOLLOCHER, T. C., E. GARBER, A. J. L. COOPER, and R. E. REIMAN. “N-13,N-15 ISOTOPE AND KINETIC EVIDENCE AGAINST HYPONITRITE AS AN INTERMEDIATE IN DENITRIFICATION.” Journal of Biological Chemistry 255, no. 11 (January 1, 1980): 5027–30.
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  - Gelbard, A. S., R. S. Benua, J. S. Laughlin, G. Rosen, R. E. Reiman, and J. M. McDonald. “Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate..” Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 20, no. 7 (July 1979): 782–84.
  - Lockwood, A. H., J. M. McDonald, R. E. Reiman, A. S. Gelbard, J. S. Laughlin, T. E. Duffy, and F. Plum. “The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia..” The Journal of Clinical Investigation 63, no. 3 (March 1979): 449–60. https://doi.org/10.1172/jci109322.
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- Book Sections
  - Dobbins, J. T., D. P. Frush, C. J. N. Kigongo, J. R. MacFall, R. E. Reiman, and G. E. Trahey. “Medical imaging safety in the developing world.” In Radiology in Global Health: Strategies, Implementation, and Applications, 9781461406044:41–60, 2014. https://doi.org/10.1007/978-1-4614-0604-4_7.
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  - Coleman, R. E., S. Borges-Neto, R. H. Wilkinson, S. M. O’Hara, M. W. Hanson, R. R. Reiman, R. J. Hagge, and B. B. Chin. “Nuclear medicine.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 2012.
  - Reiman, R. R., and R. E. Coleman. “Nuclear medicine: Case 14.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 566–67, 2012.
- Conference Papers
  - Hill, Kevin D., Christoph P. Hornik, Jennifer S. Li, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Jason Johnson. “Radiation Exposure and Estimated Lifetime Attributable Risk of Cancer From Cardiac Catheterization in Children.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Chin, Bennett, Robert Reiman, Haijing Song, and Ganesan Vaidyanathan. “Radiation dose estimates of [123I] and [131I] iodoquine, putative radiotracers targeting cells with high ALDH expression.” In Journal of Nuclear Medicine, Vol. 50. SOC NUCLEAR MEDICINE INC, 2009.
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Teaching & Mentoring
Recent Courses
- MEDPHY 505: Anatomy and Physiology for Medical Physicists 2019
- MEDPHY 743: Basic Concepts of Internal Radiation Dosimetry 2019

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Education, Training, & Certifications

Duke Appointment History

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses