Robert Ellis Reiman Jr. | Scholars@Duke

Robert Ellis Reiman Jr.
Associate Professor of Radiology

Dr. Reiman is diplomate of the American Board of Nuclear Medicine, and is the Associate Director the Radiation Safety Division of Duke's Occupational and Environmental Safety Office. He is on the faculty the Department of Radiology and a member of the Faculty of the Duke Medical Physics Graduate Program. He coordinates the patient care activities of the Duke Radiation Safety Division and participates in the teaching of radiology residents, and cardiology fellows and medical students. His current research interests include internal radionuclide dosimetry and the application of Web-based systems to problems in radiation safety and dosimetry. He has also published on imaging of bone, brain and soft-tissue tumors with nitrogen-13 labeled amino acids.

Current Appointments & Affiliations

Associate Professor of Radiology, Radiology, Clinical Science Departments 2013

Contact Information

409 Elf Street, Durham, NC 27705
Box 3155 Med Ctr, Durham, NC 27710
robert.reiman@duke.edu (919) 668-3186

Background
Education, Training, & Certifications
- M.D., Case Western Reserve University 1987
Duke Appointment History
- Assistant Professor of Radiology, Radiology, Clinical Science Departments 2006 - 2013
- Assistant Clinical Professor of Radiology, Radiology, Clinical Science Departments 1999 - 2006
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1995
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1989 - 1994
Expertise
Subject Headings
Research
Selected Grants
- Health Physics: Accelerator Health Physics; Reactor Health Physics 2012 - 2014
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Development of Nuclear Safety Graduate Level Courses Including Radionuclide Therapy Training Modules and Radiation Protection Laboratory Exercises 2007 - 2011
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Mann, Steve D., Anand Joshi, Megan Shonyo, Jered R. Wells, Jocelyn Hoye, Greeshma Agasthya, Robert Reiman, and Ehsan Samei. “Improved Dose Estimates for Fluoroscopically Guided Lumbar Epidural Injections.” Pain Med 20, no. 5 (May 1, 2019): 971–78. https://doi.org/10.1093/pm/pny172.
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  - Kane, Ari, Matthew P. Thorpe, Michael A. Morse, Brandon A. Howard, Jorge D. Oldan, Jason Zhu, Terence Z. Wong, Neil A. Petry, Robert Reiman, and Salvador Borges-Neto. “Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG.” J Nucl Med 59, no. 11 (November 2018): 1708–13. https://doi.org/10.2967/jnumed.117.202150.
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  - Chin, Bennett B., Darryl McDougald, Douglas H. Weitzel, Thomas Hawk, Robert E. Reiman, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine.” Curr Radiopharm 10, no. 1 (2017): 41–50. https://doi.org/10.2174/1874471009666161230114954.
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  - Howard, Brandon A., Olga G. James, Jennifer M. Perkins, Robert A. Pagnanelli, Salvador Borges-Neto, and Robert E. Reiman. “A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.” Sage Open Med Case Rep 5 (2017): 2050313X17745203. https://doi.org/10.1177/2050313X17745203.
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  - Chin, Bennett, Darryl McDougald, Douglas Weitzel, Thomas Hawk, Robert Reiman, Michael Zalutsky, and Ganesan Vaidyanathan. “Synthesis and preliminary evaluation of 5-[18F]fluoroleucine: a novel LAT1 substrate.” Journal of Nuclear Medicine 57 (May 1, 2016).
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  - Hoang, Jenny K., Robert E. Reiman, Giao B. Nguyen, Natalie Januzis, Bennett B. Chin, Carolyn Lowry, and Terry T. Yoshizumi. “Lifetime Attributable Risk of Cancer From Radiation Exposure During Parathyroid Imaging: Comparison of 4D CT and Parathyroid Scintigraphy.” Ajr Am J Roentgenol 204, no. 5 (May 2015): W579–85. https://doi.org/10.2214/AJR.14.13278.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease".” Circulation 131, no. 16 (April 21, 2015): e419–20. https://doi.org/10.1161/CIRCULATIONAHA.114.013266.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry T. Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease.” Circulation 130, no. 2 (July 8, 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
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  - Samei, Ehsan, Xiang Li, Baiyu Chen, and Robert Reiman. “The effect of dose heterogeneity on radiation risk in medical imaging.” Radiat Prot Dosimetry 155, no. 1 (June 2013): 42–58. https://doi.org/10.1093/rpd/ncs275.
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  - Reiman, Robert E. “Informed consent in human research: what to say and how to say it.” Health Phys 104, no. 2 Suppl 1 (February 2013): S17–22. https://doi.org/10.1097/HP.0b013e318271b4c9.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Sara K. Pasquali, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cancer Risk Estimation from Cardiac Catheterization in Children with Heart Disease.” Circulation 126, no. 21 (November 20, 2012).
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  - Edwards, Ben E., and Robert E. Reiman. “Comparison of current and past surgical smoke control practices.” Aorn J 95, no. 3 (March 2012): 337–50. https://doi.org/10.1016/j.aorn.2011.07.019.
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  - Chin, Bennett B., Anita Hjelemand, Jeremy Rich, Haijing Song, Christopher Lascola, Robert Storms, Roger McLendon, et al. “Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression.” Curr Radiopharm 5, no. 1 (January 2012): 47–58. https://doi.org/10.2174/1874471011205010047.
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  - Reiman, R. E. “Radiation protection of technologists and ancillary personnel,” December 1, 2011, 83–90. https://doi.org/10.1007/978-0-387-48902-5_8.
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  - Edwards, Ben E., and Robert E. Reiman. “Results of a survey on current surgical smoke control practices.” Aorn J 87, no. 4 (April 2008): 739–49. https://doi.org/10.1016/j.aorn.2007.11.001.
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  - Hurwitz, Lynne M., Robert E. Reiman, Terry T. Yoshizumi, Philip C. Goodman, Greta Toncheva, Giao Nguyen, and Carolyn Lowry. “Radiation dose from contemporary cardiothoracic multidetector CT protocols with an anthropomorphic female phantom: implications for cancer induction.” Radiology 245, no. 3 (December 2007): 742–50. https://doi.org/10.1148/radiol.2453062046.
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  - Hurwitz, Lynne M., Terry T. Yoshizumi, Robert E. Reiman, Erik K. Paulson, Donald P. Frush, Giao T. Nguyen, Greta I. Toncheva, and Philip C. Goodman. “Radiation dose to the female breast from 16-MDCT body protocols.” Ajr Am J Roentgenol 186, no. 6 (June 2006): 1718–22. https://doi.org/10.2214/AJR.04.1917.
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  - Hurwitz, Lynne M., Terry Yoshizumi, Robert E. Reiman, Philip C. Goodman, Erik K. Paulson, Donald P. Frush, Greta Toncheva, Giao Nguyen, and Lottie Barnes. “Radiation dose to the fetus from body MDCT during early gestation.” Ajr Am J Roentgenol 186, no. 3 (March 2006): 871–76. https://doi.org/10.2214/AJR.04.1915.
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  - Reiman, R. “TU‐B‐I‐611‐01: Releasing Nuclear Medicine Patients to the Public: Dose Computations and Discharge Instructions.” Medical Physics 32, no. 6 (January 1, 2005): 2077. https://doi.org/10.1118/1.1998328.
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  - DeGrado, Timothy R., Robert E. Reiman, David T. Price, Shuyan Wang, and R Edward Coleman. “Pharmacokinetics and radiation dosimetry of 18F-fluorocholine.” J Nucl Med 43, no. 1 (January 2002): 92–96.
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  - DeGrado, T. R., S. W. Baldwin, S. Wang, M. D. Orr, R. P. Liao, H. S. Friedman, R. Reiman, D. T. Price, and R. E. Coleman. “Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers.” J Nucl Med 42, no. 12 (December 2001): 1805–14.
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  - Brown, M. T., R. E. Coleman, A. H. Friedman, H. S. Friedman, R. E. McLendon, R. Reiman, G. J. Felsberg, et al. “Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.” Clin Cancer Res 2, no. 6 (June 1996): 963–72.
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  - Reiman, R. E., and J. K. Fetters. “Localization of technetium-99m-sestamibi in diffuse myelodysplastic processes.” J Nucl Med 37, no. 3 (March 1996): 471–73.
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  - King, S. C., R. J. Reiman, and L. R. Prosnitz. “Prognostic importance of restaging gallium scans following induction chemotherapy for advanced Hodgkin's disease.” J Clin Oncol 12, no. 2 (February 1994): 306–11. https://doi.org/10.1200/JCO.1994.12.2.306.
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  - Schmall, B., P. S. Conti, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, R. S. Benua, S. D. Yeh, J. R. Dahl, R. Lee, and J. S. Laughlin. “Imaging studies of patients with malignant fibrous histiocytoma using C-11-alpha-aminoisobutyric acid (AIB).” Clin Nucl Med 12, no. 1 (January 1987): 22–26. https://doi.org/10.1097/00003072-198701000-00005.
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  - Sordillo, P. P., R. S. Benua, A. S. Gelbard, J. Bading, R. E. Reiman, G. B. Magill, and J. S. Laughlin. “Imaging of human tumors and organs with N-13-labeled L-methionine.” Am J Physiol Imaging 1, no. 4 (1986): 195–200.
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  - Kurzweil, P. R., D. R. Miller, J. E. Freeman, R. E. Reiman, and K. Mayer. “Use of sodium chromate Cr51 in diagnosing childhood idiopathic pulmonary hemosiderosis.” Am J Dis Child 138, no. 8 (August 1984): 746–48. https://doi.org/10.1001/archpedi.1984.02140460038012.
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  - Conti, P. S., B. Schmall, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, J. R. Dahl, J. K. Jacobsen, R. Lee, and M. B. Winstead. “Synthesis and purification of sodium [11C]benzoate for physiological and metabolic studies: evaluation in a tumor-bearing dog.” Int J Nucl Med Biol 11, no. 2 (1984): 179–83. https://doi.org/10.1016/0047-0740(84)90058-5.
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  - Warrell, R. P., S. J. Kempin, R. S. Benua, R. E. Reiman, and C. W. Young. “Intratumoral consumption of indium-111 labeled platelets in a patient with hemangiomatosis and intravascular coagulation (Kasabach-Merritt syndrome).” Cancer 52, no. 12 (December 15, 1983): 2256–60. https://doi.org/10.1002/1097-0142(19831215)52:12<2256::aid-cncr2820521216>3.0.co;2-9.
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  - Sordillo, P. P., R. E. Reiman, R. S. Benua, A. S. Gelbard, G. B. Magill, G. Rosen, and J. S. Laughlin. “Quantitative scanning of soft-tissue sarcomas with nitrogen-13-labeled L-glutamate.” Cancer Invest 1, no. 5 (1983): 387–93. https://doi.org/10.3109/07357908309048507.
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  - Reiman, R. E., R. S. Benua, A. S. Gelbard, J. C. Allen, J. J. Vomero, and J. S. Laughlin. “Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.” J Nucl Med 23, no. 8 (August 1982): 682–87.
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  - Sordillo, P. P., R. E. Reiman, A. S. Gelbard, R. S. Benua, G. B. Magill, and J. S. Laughlin. “Scanning with L-(13 N) glutamate: Assessment of the response to chemotherapy of a patient with embryonal rhabdomyosarcoma.” Am J Clin Oncol 5, no. 3 (June 1982): 285–89.
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  - Reiman, R. E., G. Rosen, A. S. Gelbard, R. S. Benua, and J. S. Laughlin. “Imaging of primary Ewing sarcoma with 13N-L-glutamate.” Radiology 142, no. 2 (February 1982): 495–500. https://doi.org/10.1148/radiology.142.2.6119736.
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  - REIMAN, R. E. “DIAGNOSIS OF ALCOHOLIC CIRRHOSIS WITH THE RIGHT-TO-LEFT HEPATIC LOBE RATIO - CONCISE COMMUNICATION.” Journal of Nuclear Medicine 23, no. 1 (January 1, 1982): 80–80.
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  - Reiman, R. E. “Re:diagnosis of alcoholic cirrhosis with the right-to-left hepatic lobe ratio: concise communication.” J Nucl Med 23, no. 1 (January 1982): 80.
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  - Reiman, R. E., A. G. Huvos, R. S. Benua, G. Rosen, A. S. Gelbard, and J. S. Laughlin. “Quotient imaging with N-13 L-glutamate in osteogenic sarcoma: correlation with tumor viability.” Cancer 48, no. 9 (November 1, 1981): 1976–81. https://doi.org/10.1002/1097-0142(19811101)48:9<1976::aid-cncr2820480912>3.0.co;2-x.
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  - Digenis, G. A., S. H. Vincent, C. S. Kook, R. E. Reiman, G. A. Russ, and R. S. Tilbury. “Tissue distribution studies of [18F]haloperidol, [18F]-beta-(4-fluorobenzoyl)propionic acid, and [82Br]bromperidol by external scintigraphy.” J Pharm Sci 70, no. 9 (September 1981): 985–89. https://doi.org/10.1002/jps.2600700904.
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  - GELBARD, A. S., B. R. FREED, R. E. REIMAN, and A. J. L. COOPER. “N-13-LABELED L-AMINO-ACIDS - ENZYMATIC SYNTHESES AND METABOLIC STUDIES.” Advances in Chemistry Series, no. 197 (January 1, 1981): 389–403.
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  - Gelbard, A. S., R. S. Benua, R. E. Reiman, J. M. McDonald, J. J. Vomero, and J. S. Laughlin. “Imaging of the human heart after administration of L-(N-13)glutamate.” J Nucl Med 21, no. 10 (October 1980): 988–91.
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  - Hollocher, T. C., E. Garber, A. J. Cooper, and R. E. Reiman. “13N,15N isotope and kinetic evidence against hyponitrite as an intermediate in dentrification.” J Biol Chem 255, no. 11 (June 10, 1980): 5027–30.
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  - HOLLOCHER, T. C., E. GARBER, A. J. L. COOPER, and R. E. REIMAN. “N-13,N-15 ISOTOPE AND KINETIC EVIDENCE AGAINST HYPONITRITE AS AN INTERMEDIATE IN DENITRIFICATION.” Journal of Biological Chemistry 255, no. 11 (January 1, 1980): 5027–30.
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  - Gelbard, A. S., R. S. Benua, J. S. Laughlin, G. Rosen, R. E. Reiman, and J. M. McDonald. “Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate.” J Nucl Med 20, no. 7 (July 1979): 782–84.
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  - Lockwood, A. H., J. M. McDonald, R. E. Reiman, A. S. Gelbard, J. S. Laughlin, T. E. Duffy, and F. Plum. “The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia.” J Clin Invest 63, no. 3 (March 1979): 449–60. https://doi.org/10.1172/JCI109322.
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- Book Sections
  - Dobbins, J. T., D. P. Frush, C. J. N. Kigongo, J. R. MacFall, R. E. Reiman, G. E. Trahey, and D. P. Bradway. “Medical imaging safety in global health radiology.” In Radiology in Global Health: Strategies, Implementation, and Applications, 85–105, 2018. https://doi.org/10.1007/978-3-319-98485-8_9.
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  - Dobbins, J. T., D. P. Frush, C. J. N. Kigongo, J. R. MacFall, R. E. Reiman, and G. E. Trahey. “Medical imaging safety in the developing world.” In Radiology in Global Health: Strategies, Implementation, and Applications, 9781461406044:41–60, 2014. https://doi.org/10.1007/978-1-4614-0604-4_7.
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  - Coleman, R. E., S. Borges-Neto, R. H. Wilkinson, S. M. O’Hara, M. W. Hanson, R. R. Reiman, R. J. Hagge, and B. B. Chin. “Nuclear medicine.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 2012.
  - Reiman, R. R., and R. E. Coleman. “Nuclear medicine: Case 14.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 566–67, 2012.
- Conference Papers
  - Hill, Kevin D., Christoph P. Hornik, Jennifer S. Li, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Jason Johnson. “Radiation Exposure and Estimated Lifetime Attributable Risk of Cancer From Cardiac Catheterization in Children.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Chin, Bennett, Robert Reiman, Haijing Song, and Ganesan Vaidyanathan. “Radiation dose estimates of [123I] and [131I] iodoquine, putative radiotracers targeting cells with high ALDH expression.” In Journal of Nuclear Medicine, Vol. 50. SOC NUCLEAR MEDICINE INC, 2009.
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Teaching & Mentoring
Recent Courses
- MEDPHY 743: Basic Concepts of Internal Radiation Dosimetry 2020
- MEDPHY 505: Anatomy and Physiology for Medical Physicists 2019

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Education, Training, & Certifications

Duke Appointment History

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses