Robert Ellis Reiman Jr. | Scholars@Duke

Robert Ellis Reiman Jr.
Associate Professor of Radiology

Dr. Reiman is diplomate of the American Board of Nuclear Medicine, and is the Associate Director the Radiation Safety Division of Duke's Occupational and Environmental Safety Office. He is on the faculty the Department of Radiology and is a member of the Faculty of the Duke Medical Physics Graduate Program. He coordinates the patient care activities of the Duke Radiation Safety Division and participates in the teaching of radiology residents, nuclear medicine fellows, cardiology fellows and medical students. His current research interests include internal radionuclide dosimetry and the application of Web-based systems to problems in radiation safety and dosimetry. He has also published on imaging of bone, brain and soft-tissue tumors with nitrogen-13 labeled amino acids.

Current Appointments & Affiliations

Associate Professor of Radiology, Radiology, Clinical Science Departments 2021

Contact Information

409 Elf Street, Durham, NC 27705
Box 3155 Med Ctr, Durham, NC 27710
robert.reiman@duke.edu (919) 668-3186

Background
Education, Training, & Certifications
- ABMS Member Board, American Board of Nuclear Medicine 1992
- Nuclear Medicine Fellowship, Radiology, Duke University School of Medicine 1989 - 1991
- Residency and Internship, Internal Medicine, University Hospitals of Cleveland 1987 - 1989
- M.D., Case Western Reserve University 1987
Previous Appointments & Affiliations
- Associate Professor of Radiology, Radiology, Clinical Science Departments 2013 - 2020
- Assistant Professor of Radiology, Radiology, Clinical Science Departments 2006 - 2013
- Assistant Clinical Professor of Radiology, Radiology, Clinical Science Departments 1999 - 2006
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1995
- Associate in the Department of Radiology, Radiology, Nuclear Medicine, Radiology 1989 - 1994
Recognition
Awards & Honors
- First Prize, Outstanding Clinical Investigations. Society of Nuclear Medicine. 2002
Expertise
Subject Headings
Research
Selected Grants
- Health Physics: Accelerator Health Physics; Reactor Health Physics awarded by U.S. Nuclear Regulatory Commission 2012 - 2014
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- Development of Nuclear Safety Graduate Level Courses Including Radionuclide Therapy Training Modules and Radiation Protection Laboratory Exercises awarded by U.S. Nuclear Regulatory Commission 2007 - 2011
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Feng, Yutian, Rebecca Meshaw, Darryl McDougald, Zhengyuan Zhou, Xiao-Guang Zhao, Stephen A. Jannetti, Robert E. Reiman, et al. “Evaluation of an 131I-labeled HER2-specific single domain antibody fragment for the radiopharmaceutical therapy of HER2-expressing cancers.” Sci Rep 12, no. 1 (February 22, 2022): 3020. https://doi.org/10.1038/s41598-022-07006-9.
    Full Text Link to Item
  - Mann, Steve D., Anand Joshi, Megan Shonyo, Jered R. Wells, Jocelyn Hoye, Greeshma Agasthya, Robert Reiman, and Ehsan Samei. “Improved Dose Estimates for Fluoroscopically Guided Lumbar Epidural Injections.” Pain Med 20, no. 5 (May 1, 2019): 971–78. https://doi.org/10.1093/pm/pny172.
    Full Text Link to Item
  - Kane, Ari, Matthew P. Thorpe, Michael A. Morse, Brandon A. Howard, Jorge D. Oldan, Jason Zhu, Terence Z. Wong, Neil A. Petry, Robert Reiman, and Salvador Borges-Neto. “Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG.” J Nucl Med 59, no. 11 (November 2018): 1708–13. https://doi.org/10.2967/jnumed.117.202150.
    Full Text Open Access Copy Link to Item
  - Chin, Bennett B., Darryl McDougald, Douglas H. Weitzel, Thomas Hawk, Robert E. Reiman, Michael R. Zalutsky, and Ganesan Vaidyanathan. “Synthesis and Preliminary Evaluation of 5-[18F]fluoroleucine.” Curr Radiopharm 10, no. 1 (2017): 41–50. https://doi.org/10.2174/1874471009666161230114954.
    Full Text Open Access Copy Link to Item
  - Howard, Brandon A., Olga G. James, Jennifer M. Perkins, Robert A. Pagnanelli, Salvador Borges-Neto, and Robert E. Reiman. “A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.” Sage Open Med Case Rep 5 (2017): 2050313X17745203. https://doi.org/10.1177/2050313X17745203.
    Full Text Open Access Copy Link to Item
  - Chin, B. B., D. McDougald, D. Weitzel, T. Hawk, R. E. Reiman, M. R. Zalutsky, and G. Vaidyanathan. “Synthesis and preliminary evaluation of 5-[18F]fluoroleucine: a novel LAT1 substrate (In preparation).” Current Radiopharmaceuticals, 2016.
  - Hoang, Jenny K., Robert E. Reiman, Giao B. Nguyen, Natalie Januzis, Bennett B. Chin, Carolyn Lowry, and Terry T. Yoshizumi. “Lifetime Attributable Risk of Cancer From Radiation Exposure During Parathyroid Imaging: Comparison of 4D CT and Parathyroid Scintigraphy.” Ajr Am J Roentgenol 204, no. 5 (May 2015): W579–85. https://doi.org/10.2214/AJR.14.13278.
    Full Text Link to Item
  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease".” Circulation 131, no. 16 (April 21, 2015): e419–20. https://doi.org/10.1161/CIRCULATIONAHA.114.013266.
    Full Text Link to Item
  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry T. Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease.” Circulation 130, no. 2 (July 8, 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
    Full Text Link to Item
  - Samei, Ehsan, Xiang Li, Baiyu Chen, and Robert Reiman. “The effect of dose heterogeneity on radiation risk in medical imaging.” Radiat Prot Dosimetry 155, no. 1 (June 2013): 42–58. https://doi.org/10.1093/rpd/ncs275.
    Full Text Link to Item
  - Reiman, Robert E. “Informed consent in human research: what to say and how to say it.” Health Phys 104, no. 2 Suppl 1 (February 2013): S17–22. https://doi.org/10.1097/HP.0b013e318271b4c9.
    Full Text Link to Item
  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Sara K. Pasquali, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cancer Risk Estimation from Cardiac Catheterization in Children with Heart Disease.” Circulation 126, no. 21 (November 20, 2012).
    Link to Item
  - Edwards, Ben E., and Robert E. Reiman. “Comparison of current and past surgical smoke control practices.” Aorn J 95, no. 3 (March 2012): 337–50. https://doi.org/10.1016/j.aorn.2011.07.019.
    Full Text Link to Item
  - Chin, Bennett B., Anita Hjelemand, Jeremy Rich, Haijing Song, Christopher Lascola, Robert Storms, Roger McLendon, et al. “Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression.” Curr Radiopharm 5, no. 1 (January 2012): 47–58. https://doi.org/10.2174/1874471011205010047.
    Full Text Link to Item
  - Reiman, R. E. “Radiation protection of technologists and ancillary personnel,” December 1, 2011, 83–90. https://doi.org/10.1007/978-0-387-48902-5_8.
    Full Text
  - Edwards, Ben E., and Robert E. Reiman. “Results of a survey on current surgical smoke control practices.” Aorn J 87, no. 4 (April 2008): 739–49. https://doi.org/10.1016/j.aorn.2007.11.001.
    Full Text Link to Item
  - Hurwitz, Lynne M., Robert E. Reiman, Terry T. Yoshizumi, Philip C. Goodman, Greta Toncheva, Giao Nguyen, and Carolyn Lowry. “Radiation dose from contemporary cardiothoracic multidetector CT protocols with an anthropomorphic female phantom: implications for cancer induction.” Radiology 245, no. 3 (December 2007): 742–50. https://doi.org/10.1148/radiol.2453062046.
    Full Text Link to Item
  - Hurwitz, Lynne M., Terry T. Yoshizumi, Robert E. Reiman, Erik K. Paulson, Donald P. Frush, Giao T. Nguyen, Greta I. Toncheva, and Philip C. Goodman. “Radiation dose to the female breast from 16-MDCT body protocols.” Ajr Am J Roentgenol 186, no. 6 (June 2006): 1718–22. https://doi.org/10.2214/AJR.04.1917.
    Full Text Link to Item
  - Hurwitz, Lynne M., Terry Yoshizumi, Robert E. Reiman, Philip C. Goodman, Erik K. Paulson, Donald P. Frush, Greta Toncheva, Giao Nguyen, and Lottie Barnes. “Radiation dose to the fetus from body MDCT during early gestation.” Ajr Am J Roentgenol 186, no. 3 (March 2006): 871–76. https://doi.org/10.2214/AJR.04.1915.
    Full Text Link to Item
  - Reiman, R. “TU‐B‐I‐611‐01: Releasing Nuclear Medicine Patients to the Public: Dose Computations and Discharge Instructions.” Medical Physics 32, no. 6 (January 1, 2005): 2077. https://doi.org/10.1118/1.1998328.
    Full Text
  - DeGrado, Timothy R., Robert E. Reiman, David T. Price, Shuyan Wang, and R Edward Coleman. “Pharmacokinetics and radiation dosimetry of 18F-fluorocholine.” J Nucl Med 43, no. 1 (January 2002): 92–96.
    Link to Item
  - DeGrado, T. R., S. W. Baldwin, S. Wang, M. D. Orr, R. P. Liao, H. S. Friedman, R. Reiman, D. T. Price, and R. E. Coleman. “Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers.” J Nucl Med 42, no. 12 (December 2001): 1805–14.
    Link to Item
  - Brown, M. T., R. E. Coleman, A. H. Friedman, H. S. Friedman, R. E. McLendon, R. Reiman, G. J. Felsberg, et al. “Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.” Clin Cancer Res 2, no. 6 (June 1996): 963–72.
    Link to Item
  - Reiman, R. E., and J. K. Fetters. “Localization of technetium-99m-sestamibi in diffuse myelodysplastic processes.” J Nucl Med 37, no. 3 (March 1996): 471–73.
    Link to Item
  - King, S. C., R. J. Reiman, and L. R. Prosnitz. “Prognostic importance of restaging gallium scans following induction chemotherapy for advanced Hodgkin's disease.” J Clin Oncol 12, no. 2 (February 1994): 306–11. https://doi.org/10.1200/JCO.1994.12.2.306.
    Full Text Link to Item
  - Schmall, B., P. S. Conti, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, R. S. Benua, S. D. Yeh, J. R. Dahl, R. Lee, and J. S. Laughlin. “Imaging studies of patients with malignant fibrous histiocytoma using C-11-alpha-aminoisobutyric acid (AIB).” Clin Nucl Med 12, no. 1 (January 1987): 22–26. https://doi.org/10.1097/00003072-198701000-00005.
    Full Text Link to Item
  - Sordillo, P. P., R. S. Benua, A. S. Gelbard, J. Bading, R. E. Reiman, G. B. Magill, and J. S. Laughlin. “Imaging of human tumors and organs with N-13-labeled L-methionine.” Am J Physiol Imaging 1, no. 4 (1986): 195–200.
    Link to Item
  - Kurzweil, P. R., D. R. Miller, J. E. Freeman, R. E. Reiman, and K. Mayer. “Use of sodium chromate Cr51 in diagnosing childhood idiopathic pulmonary hemosiderosis.” Am J Dis Child 138, no. 8 (August 1984): 746–48. https://doi.org/10.1001/archpedi.1984.02140460038012.
    Full Text Link to Item
  - Conti, P. S., B. Schmall, R. E. Bigler, P. B. Zanzonico, R. E. Reiman, J. R. Dahl, J. K. Jacobsen, R. Lee, and M. B. Winstead. “Synthesis and purification of sodium [11C]benzoate for physiological and metabolic studies: evaluation in a tumor-bearing dog.” Int J Nucl Med Biol 11, no. 2 (1984): 179–83. https://doi.org/10.1016/0047-0740(84)90058-5.
    Full Text Link to Item
  - Warrell, R. P., S. J. Kempin, R. S. Benua, R. E. Reiman, and C. W. Young. “Intratumoral consumption of indium-111 labeled platelets in a patient with hemangiomatosis and intravascular coagulation (Kasabach-Merritt syndrome).” Cancer 52, no. 12 (December 15, 1983): 2256–60. https://doi.org/10.1002/1097-0142(19831215)52:12<2256::aid-cncr2820521216>3.0.co;2-9.
    Full Text Link to Item
  - Sordillo, P. P., R. E. Reiman, R. S. Benua, A. S. Gelbard, G. B. Magill, G. Rosen, and J. S. Laughlin. “Quantitative scanning of soft-tissue sarcomas with nitrogen-13-labeled L-glutamate.” Cancer Invest 1, no. 5 (1983): 387–93. https://doi.org/10.3109/07357908309048507.
    Full Text Link to Item
  - Reiman, R. E., R. S. Benua, A. S. Gelbard, J. C. Allen, J. J. Vomero, and J. S. Laughlin. “Imaging of brain tumors after administration of L-(N-13)glutamate: concise communication.” J Nucl Med 23, no. 8 (August 1982): 682–87.
    Link to Item
  - Sordillo, P. P., R. E. Reiman, A. S. Gelbard, R. S. Benua, G. B. Magill, and J. S. Laughlin. “Scanning with L-(13 N) glutamate: Assessment of the response to chemotherapy of a patient with embryonal rhabdomyosarcoma.” Am J Clin Oncol 5, no. 3 (June 1982): 285–89.
    Link to Item
  - Reiman, R. E., G. Rosen, A. S. Gelbard, R. S. Benua, and J. S. Laughlin. “Imaging of primary Ewing sarcoma with 13N-L-glutamate.” Radiology 142, no. 2 (February 1982): 495–500. https://doi.org/10.1148/radiology.142.2.6119736.
    Full Text Link to Item
  - REIMAN, R. E. “DIAGNOSIS OF ALCOHOLIC CIRRHOSIS WITH THE RIGHT-TO-LEFT HEPATIC LOBE RATIO - CONCISE COMMUNICATION.” Journal of Nuclear Medicine 23, no. 1 (January 1, 1982): 80–80.
    Link to Item
  - Reiman, R. E. “Re:diagnosis of alcoholic cirrhosis with the right-to-left hepatic lobe ratio: concise communication.” J Nucl Med 23, no. 1 (January 1982): 80.
    Link to Item
  - Reiman, R. E., A. G. Huvos, R. S. Benua, G. Rosen, A. S. Gelbard, and J. S. Laughlin. “Quotient imaging with N-13 L-glutamate in osteogenic sarcoma: correlation with tumor viability.” Cancer 48, no. 9 (November 1, 1981): 1976–81. https://doi.org/10.1002/1097-0142(19811101)48:9<1976::aid-cncr2820480912>3.0.co;2-x.
    Full Text Link to Item
  - Digenis, G. A., S. H. Vincent, C. S. Kook, R. E. Reiman, G. A. Russ, and R. S. Tilbury. “Tissue distribution studies of [18F]haloperidol, [18F]-beta-(4-fluorobenzoyl)propionic acid, and [82Br]bromperidol by external scintigraphy.” J Pharm Sci 70, no. 9 (September 1981): 985–89. https://doi.org/10.1002/jps.2600700904.
    Full Text Link to Item
  - GELBARD, A. S., B. R. FREED, R. E. REIMAN, and A. J. L. COOPER. “N-13-LABELED L-AMINO-ACIDS - ENZYMATIC SYNTHESES AND METABOLIC STUDIES.” Advances in Chemistry Series, no. 197 (January 1, 1981): 389–403.
    Link to Item
  - Gelbard, A. S., R. S. Benua, R. E. Reiman, J. M. McDonald, J. J. Vomero, and J. S. Laughlin. “Imaging of the human heart after administration of L-(N-13)glutamate.” J Nucl Med 21, no. 10 (October 1980): 988–91.
    Link to Item
  - Hollocher, T. C., E. Garber, A. J. Cooper, and R. E. Reiman. “13N,15N isotope and kinetic evidence against hyponitrite as an intermediate in dentrification.” J Biol Chem 255, no. 11 (June 10, 1980): 5027–30.
    Link to Item
  - HOLLOCHER, T. C., E. GARBER, A. J. L. COOPER, and R. E. REIMAN. “N-13,N-15 ISOTOPE AND KINETIC EVIDENCE AGAINST HYPONITRITE AS AN INTERMEDIATE IN DENITRIFICATION.” Journal of Biological Chemistry 255, no. 11 (January 1, 1980): 5027–30.
    Link to Item
  - Gelbard, A. S., R. S. Benua, J. S. Laughlin, G. Rosen, R. E. Reiman, and J. M. McDonald. “Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate.” J Nucl Med 20, no. 7 (July 1979): 782–84.
    Link to Item
  - Lockwood, A. H., J. M. McDonald, R. E. Reiman, A. S. Gelbard, J. S. Laughlin, T. E. Duffy, and F. Plum. “The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia.” J Clin Invest 63, no. 3 (March 1979): 449–60. https://doi.org/10.1172/JCI109322.
    Full Text Link to Item
- Book Sections
  - Dobbins, J. T., D. P. Frush, C. J. N. Kigongo, J. R. MacFall, R. E. Reiman, G. E. Trahey, and D. P. Bradway. “Medical imaging safety in global health radiology.” In Radiology in Global Health: Strategies, Implementation, and Applications, 85–105, 2018. https://doi.org/10.1007/978-3-319-98485-8_9.
    Full Text
  - Dobbins, J. T., D. P. Frush, C. J. N. Kigongo, J. R. MacFall, R. E. Reiman, and G. E. Trahey. “Medical imaging safety in the developing world.” In Radiology in Global Health: Strategies, Implementation, and Applications, 9781461406044:41–60, 2014. https://doi.org/10.1007/978-1-4614-0604-4_7.
    Full Text
  - Coleman, R. E., S. Borges-Neto, R. H. Wilkinson, S. M. O’Hara, M. W. Hanson, R. R. Reiman, R. J. Hagge, and B. B. Chin. “Nuclear medicine.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 539, 2012.
  - Reiman, R. R., and R. E. Coleman. “Nuclear medicine: Case 14.” In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 566–67, 2012.
- Conference Papers
  - Yu, T., R. E. Reiman, and J. E. Bowsher. “Seven-Pinhole Versus Single-Pinhole SPECT for Thyroid Imaging.” In 2020 Ieee Nuclear Science Symposium and Medical Imaging Conference, Nss/Mic 2020, 2020. https://doi.org/10.1109/NSS/MIC42677.2020.9507803.
    Full Text
  - Hill, Kevin D., Christoph P. Hornik, Jennifer S. Li, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Jason Johnson. “Radiation Exposure and Estimated Lifetime Attributable Risk of Cancer From Cardiac Catheterization in Children.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
  - Chin, B. B., R. E. Reiman, H. Song, and G. Vaidyanathan. “Radiation dose estimates of [125I] and [131I] – iodoquine, a putative radiotracer targeting cells with high ALDH expression.” In Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, Vol. 50. Society of Nuclear Medicine, 2009.
Teaching & Mentoring
Recent Courses
Teaching Activities
- Core course in Anatomy and Physiology, Duke Medical Physics Graduate Program
  Elective in Internal Radiation Dosimetry, Duke Medical Physics Graduate Program
  Annual Duke Radiology Review Course (CME)
  "New to OR" curriculum, Department of Nursing
  Nuclear Medicine Conference series, Department of Radiology
  Radiation Biology and Protection Mini-seminar, Department of Radiology
Scholarly, Clinical, & Service Activities
Service to the Profession
- Commissioner, North Carolina Radiation Protection Commission. 2018 2018
- Member, Scientific Committee SC 4-7. Nation Council on Radiation Protection and Measurements. 2014 - 2020 2014 - 2020
Service to Duke

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Previous Appointments & Affiliations

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses

Teaching Activities

Service to the Profession

Service to Duke