Research Interests
1) Mechanisms of Lung Susceptibility to Air Pollution
2) Lung macrophage and epithelial crosstalk in acute lung injury
3) Hyperpolarized 129 Xenon MRI for use in prognostic and therapeutic assessment of Interstitial Lung Disease
4) Interstitial Lung Disease Epidemiology in the Veterans Affairs Health System
5) Engineered nanomaterials and protein corona formation with airway lining fluid
2) Lung macrophage and epithelial crosstalk in acute lung injury
3) Hyperpolarized 129 Xenon MRI for use in prognostic and therapeutic assessment of Interstitial Lung Disease
4) Interstitial Lung Disease Epidemiology in the Veterans Affairs Health System
5) Engineered nanomaterials and protein corona formation with airway lining fluid
Selected Grants
Duke University Program in Environmental Health
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2019 - 2029Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRI
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2011 - 2027Monocyte-derived alveolar macrophage drives inflammatory response to lung ozone exposure
ResearchPrincipal Investigator · Awarded by National Institute of Environmental Health Sciences · 2022 - 2027Mongolian Center for Environmental & Occupational Health - U.S. Subaward
Inst. Training Prgm or CMECo Investigator · Awarded by University of Texas Medical Branch · 2022 - 2027Red blood cell ATP export and transfusion in sepsis (R01)
ResearchCollaborator · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2026Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026Genentech Xenon MRI IPF Study
Clinical TrialPrincipal Investigator · Awarded by Genentech, Inc. · 2019 - 2026Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary Fibrosis
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2015 - 2025R01: CXCL10/CXCR3 regulation of ozone-induced epithelial permeability
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2023Gene-Environment Collaboration in Autoimmune Disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2023Pulmonary response to nanomaterial-ozone exposures
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2023VACCINE AND TREATMENT EVALUATION UNITS (VTEU) PROTOCOL DEVELOPMENT, IMPLEMENTATION AND ASSAYS TASK AREA B-D PHASE 1 PK TRIAL TO EVALUATE FOSFOMYCIN TASK ORDER 16-0058.B1C1D1.0076
ResearchResearch Specialist · Awarded by National Institutes of Health · 2017 - 2022Interdisciplinary Training Program in Lung Disease
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2009 - 2021Novel role for CD163 in ozone induced alterations of pulmonary immunity
ResearchPrincipal Investigator · Awarded by East Carolina University · 2019 - 2020GA39831: An observational study to assess disease relevant outcomes using home monitoring devices in patients with idiopathic pulmonary fibrosis
ResearchPrincipal Investigator · Awarded by Genentech, Inc. · 2018 - 2019Dual humanization to model gene-environment interactions in ANCA vasculitis
ResearchCollaborator · Awarded by Vasculitis Foundation · 2017 - 2018Regulation of Lung Fibrosis by Alternatively Activated Macrophages and Arginase-1
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2017Mechanism of Silica-induced Autoimmunity
ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2017Diesel-induced Alterations of Influenza Infectivity
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2015 - 2017External Relationships
- Boehringer Ingleheim
- Procter & Gamble Company
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.