Overview
Main focus is in epilepsy, sleep disorders, and clinical neurophysiology interpretation. Specific areas of interest include predictive outcome factors in epilepsy surgery, neuroimaging characteristics of neuronal migration disorders, development of new medical treatments of epilepsy and narcolepsy, and the pharmacogenetics of epilepsy and its treatment.
No involvement in basic laboratory research.
Ongoing clinical trials include:
1) Pharmacogenetics of epilepsy
2) behavioral treatment trial for insomnia
Special expertise recognized by serving on Professional Advisory Board of the Epilepsy Foundation of America and election as chairman of the American Board of Clinical Neurophysiology (certifying body in EEG, Evoked Potentials, Epilepsy Monitoring and Sleep).
Key words: Epilepsy
Epilepsy Surgery
Sleep Disorders
Sleep Apnea
Narcolepsy
Clinical Neurophysiology
No involvement in basic laboratory research.
Ongoing clinical trials include:
1) Pharmacogenetics of epilepsy
2) behavioral treatment trial for insomnia
Special expertise recognized by serving on Professional Advisory Board of the Epilepsy Foundation of America and election as chairman of the American Board of Clinical Neurophysiology (certifying body in EEG, Evoked Potentials, Epilepsy Monitoring and Sleep).
Key words: Epilepsy
Epilepsy Surgery
Sleep Disorders
Sleep Apnea
Narcolepsy
Clinical Neurophysiology
Current Appointments & Affiliations
Professor of Neurology
·
1999 - Present
Neurology, Epilepsy and Sleep,
Neurology
Director of the Sleep Lab in the Department of Neurology
·
2006 - Present
Neurology,
Clinical Science Departments
Recent Publications
Teaching NeuroImage: Obstructive Sleep Apnea Induced by a Vagal Nerve Stimulator.
Journal Article Neurology · October 8, 2024 Full text Link to item CiteRare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy.
Journal Article Ann Neurol · December 19, 2022 OBJECTIVE: Genetic factors have long been debated as a cause of failure of surgery for mesial temporal lobe epilepsy (MTLE). We investigated whether rare genetic variation influences seizure outcomes of MTLE surgery. METHODS: We performed an international, ... Full text Link to item CiteEfficacy and safety of VNS therapy or continued medication management for treatment of adults with drug-resistant epilepsy: systematic review and meta-analysis.
Journal Article J Neurol · June 2022 Vagus nerve stimulation (VNS) Therapy® is an adjunctive neurostimulation treatment for people with drug-resistant epilepsy (DRE) who are unwilling to undergo resective surgery, have had unsuccessful surgery or are unsuitable for surgery. A systematic revie ... Full text Open Access Link to item CiteRecent Grants
Exploratory genomic investigations of mesial temporal lobe epilepsy
ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2015Classifying Psychiatric, Medical, and Primary Insomnias
ResearchClinical Interviewer · Awarded by National Institutes of Health · 2003 - 2009same
ResearchCo Investigator · Awarded by National Institutes of Health · 1994 - 2003View All Grants
Education, Training & Certifications
Northwestern University ·
1980
M.D.