Roger Edwin McLendon | Scholars@Duke

Roger Edwin McLendon
Professor of Pathology

Brain tumors are diagnosed in more than 20,000 Americans annually. The most malignant neoplasm, glioblastoma, is also the most common. Similarly, brain tumors constitute the most common solid neoplasm in children and include astrocytomas of the cerebellum, brain stem and cerebrum as well as medulloblastomas of the cerebellum. My colleagues and I have endeavored to translate the bench discoveries of genetic mutations and aberrant protein expressions found in brain tumors to better understand the processes involved in the etiology, pathogenesis, and treatment of brain tumors. Using the resources of the Preston Robert Brain Tumor Biorepository at Duke, our team, consisting of Henry Friedman, Allan Friedman, and Hai Yan and lead by Darell Bigner, have helped to identify mutations in Isocitrate Dehydrogenase (IDH1 and IDH2) as a marker of good prognosis in gliomas of adults. This test is now offered at Duke as a clinical test. Working with the Molecular Pathology Laboratory at Duke, we have also brought testing for TERT promoter region mutations as another major test for classifying gliomas in adults. Our collaboration with the Toronto Sick Kids Hospital has resulted in prognostic testing for childhood medulloblastomas, primitive neuroectodermal tumors, and ependymomas at Duke.

Current Appointments & Affiliations

Professor of Pathology, Pathology, Clinical Science Departments 2001
Professor of Neurosurgery, Neurosurgery, Neurosurgery 2018
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1992

Contact Information

Duke Box 3712, Durham, NC 27710
Msrb1, Room 181, Durham, NC 27710
roger.mclendon@duke.edu (919) 684-6940

Background
Education, Training, & Certifications
- Fellow in Neuropathology, Pathology, Duke University 1984 - 1987
- Resident, Pathology, Duke University 1983 - 1986
- M.D., Medical College of Georgia 1982
- B.A., Emory University 1979
Previous Appointments & Affiliations
- Associate Professor of Pathology with Tenure, Pathology, Clinical Science Departments 1998 - 2001
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 1992 - 1998
Academic Positions Outside Duke
- Assistant Clinical Professor of Pathology, Mercer University. 1987 - 1991
Expertise
Subject Headings
Publications & Artistic Works
Selected Publications
- Books
  - Sampson, J. H., D. D. Bigner, A. H. Friedman, H. S. Friedman, and R. McLendon. The Duke glioma handbook: Pathology, diagnosis, and management, 2016. https://doi.org/10.1017/CBO9781107588721.
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  - McLendon, R. E., M. K. Rosenblum, and D. D. Bigner. Russell and rubinstein's pathology of tumors of the nervous system, 2006.
  - McLendon, R. E., M. K. Rosenblum, and D. D. Bigner. Russell and rubinstein's pathology of tumors of the nervous system, 2006.
  - McLendon, R. E., M. K. Rosenblum, and D. D. Bigner. Russell and rubinstein's pathology of tumors of the nervous system, 2006.
- Academic Articles
  - Thompson, Eric M., Daniel Landi, Michael C. Brown, Henry S. Friedman, Roger McLendon, James E. Herndon, Evan Buckley, et al. “Recombinant polio-rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial.” Lancet Child Adolesc Health, March 30, 2023. https://doi.org/10.1016/S2352-4642(23)00031-7.
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  - Li, Sean, Roger McLendon, Eric Sankey, Reb Kornahrens, Anne-Marie Lyne, Florence Marie Géraldine Cavalli, Zachary McKay, et al. “CD155 is a putative therapeutic target in medulloblastoma.” Clin Transl Oncol 25, no. 3 (March 2023): 696–705. https://doi.org/10.1007/s12094-022-02975-9.
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  - Iorgulescu, J Bryan, Chuxuan Sun, Corey Neff, Gino Cioffi, Catherine Gutierrez, Carol Kruchko, Jennifer Ruhl, et al. “Corrigendum to: Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.” Neuro Oncol 25, no. 2 (February 14, 2023): 424–29. https://doi.org/10.1093/neuonc/noac270.
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  - Parker, Scott, Charlotte McDowall, Luis Sanchez-Perez, Cristina Osorio, Patrick C. Duncker, Aaron Briley, Adam M. Swartz, et al. “Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.” Sci Transl Med 15, no. 682 (February 8, 2023): eabn5649. https://doi.org/10.1126/scitranslmed.abn5649.
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  - Liu, Heng, Cheng Xu, Bill H. Diplas, Alexandrea Brown, Laura M. Strickland, Haipei Yao, Jinjie Ling, et al. “Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells.” Neuro Oncol, January 23, 2023. https://doi.org/10.1093/neuonc/noad022.
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  - Hendrikse, Liam D., Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H. Sjoboen, Anders W. Erickson, Winnie Ong, et al. “Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.” Nature 612, no. 7940 (December 2022): E12. https://doi.org/10.1038/s41586-022-05578-0.
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  - Iorgulescu, J Bryan, Chuxuan Sun, Corey Neff, Gino Cioffi, Catherine Gutierrez, Carol Kruchko, Jennifer Ruhl, et al. “Molecular biomarker-defined brain tumors: Epidemiology, validity, and completeness in the United States.” Neuro Oncol 24, no. 11 (November 2, 2022): 1989–2000. https://doi.org/10.1093/neuonc/noac113.
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  - Hendrikse, Liam D., Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H. Sjoboen, Anders W. Erickson, Winnie Ong, et al. “Failure of human rhombic lip differentiation underlies medulloblastoma formation.” Nature 609, no. 7929 (September 2022): 1021–28. https://doi.org/10.1038/s41586-022-05215-w.
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  - Waite, Kristin A., Gino Cioffi, Carol Kruchko, Nirav Patil, Daniel J. Brat, Janet M. Bruner, Roger E. McLendon, Tarik Tihan, Quinn T. Ostrom, and Jill S. Barnholtz-Sloan. “Aligning the Central Brain Tumor Registry of the United States (CBTRUS) histology groupings with current definitions.” Neurooncol Pract 9, no. 4 (August 2022): 317–27. https://doi.org/10.1093/nop/npac025.
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  - McLendon, Roger E., Anthony T. Yachnis, C Ryan Miller, and Ho-Keung Ng. “Central Nervous System Tumor Classification: An Update on the Integration of Tumor Genetics.” Hematol Oncol Clin North Am 36, no. 1 (February 2022): 1–21. https://doi.org/10.1016/j.hoc.2021.08.001.
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  - Yu, Shengnan, Shiyou Wei, Milan Savani, Xiang Lin, Kuang Du, Ilgen Mender, Silvia Siteni, et al. “A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.” Clin Cancer Res 27, no. 24 (December 15, 2021): 6800–6814. https://doi.org/10.1158/1078-0432.CCR-21-0374.
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  - Coltin, Hallie, Lakshmikirupa Sundaresan, Kyle S. Smith, Patryk Skowron, Luca Massimi, Charles G. Eberhart, Karisa C. Schreck, et al. “Subgroup and subtype-specific outcomes in adult medulloblastoma.” Acta Neuropathol 142, no. 5 (November 2021): 859–71. https://doi.org/10.1007/s00401-021-02358-4.
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  - Oon, Ming Liang, Sharon Y. Y. Low, Chik Hong Kuick, Jian Yuan Goh, Kenneth T. E. Chang, Roger E. McLendon, and Char Loo Tan. “An Unusual Ganglioglioma with Pseudopapillary Features and PRKAR2B-BRAF Fusion.” J Neuropathol Exp Neurol 80, no. 10 (October 26, 2021): 1000–1003. https://doi.org/10.1093/jnen/nlab099.
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  - Baroni, Lorena V., Lakshmikirupa Sundaresan, Ayala Heled, Hallie Coltin, Kristian W. Pajtler, Tong Lin, Thomas E. Merchant, et al. “Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q.” Neuro Oncology 23, no. 8 (August 2021): 1360–70. https://doi.org/10.1093/neuonc/noab034.
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  - Bidgoli, Alan, Roger E. McLendon, and J Martin Johnston. “Histologic maturation of cerebral neuroblastoma following conventional chemotherapy.” Pediatr Blood Cancer 68, no. 7 (July 2021): e29034. https://doi.org/10.1002/pbc.29034.
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  - Skowron, Patryk, Hamza Farooq, Florence M. G. Cavalli, A Sorana Morrissy, Michelle Ly, Liam D. Hendrikse, Evan Y. Wang, et al. “The transcriptional landscape of Shh medulloblastoma.” Nat Commun 12, no. 1 (March 19, 2021): 1749. https://doi.org/10.1038/s41467-021-21883-0.
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  - Kumar, Rahul, Kyle S. Smith, Maximilian Deng, Colt Terhune, Giles W. Robinson, Brent A. Orr, Anthony P. Y. Liu, et al. “Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.” J Clin Oncol 39, no. 7 (March 1, 2021): 807–21. https://doi.org/10.1200/JCO.20.01359.
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  - Gromeier, Matthias, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, et al. “Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.” Nat Commun 12, no. 1 (January 13, 2021): 352. https://doi.org/10.1038/s41467-020-20469-6.
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  - Nobre, Liana, Michal Zapotocky, Sara Khan, Kohei Fukuoka, Adriana Fonseca, Tara McKeown, David Sumerauer, et al. “Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma.” Cell Rep Med 1, no. 3 (June 23, 2020). https://doi.org/10.1016/j.xcrm.2020.100038.
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  - Chen, Lee H., Changcun Pan, Bill H. Diplas, Cheng Xu, Landon J. Hansen, Yuliang Wu, Xin Chen, et al. “The integrated genomic and epigenomic landscape of brainstem glioma.” Nat Commun 11, no. 1 (June 17, 2020): 3077. https://doi.org/10.1038/s41467-020-16682-y.
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  - Kemeny, Hanna R., Aladine A. Elsamadicy, S Harrison Farber, Cosette D. Champion, Selena J. Lorrey, Pakawat Chongsathidkiet, Karolina I. Woroniecka, et al. “Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease.” Clin Cancer Res 26, no. 5 (March 1, 2020): 1141–51. https://doi.org/10.1158/1078-0432.CCR-18-3486.
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  - Thomas, Christian, Annika Wefers, Susanne Bens, Karolina Nemes, Abbas Agaimy, Florian Oyen, Silke Vogelgesang, et al. “Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults.” Acta Neuropathol 139, no. 2 (February 2020): 277–86. https://doi.org/10.1007/s00401-019-02094-w.
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  - Flores, C., T. Wildes, B DiVita Dean, G. Moore, J. Drake, R. Abraham, J. Gil, et al. “Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.” Sci Adv 5, no. 11 (November 2019): eaav9879. https://doi.org/10.1126/sciadv.aav9879.
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  - Harrison, William, Aladine A. Elsamadicy, J Tanner McMahon, Gustavo Chagoya, Raymond A. Sobel, Roger E. McLendon, and Cory Adamson. “Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas.” J Neuropathol Exp Neurol 78, no. 9 (September 1, 2019): 780–87. https://doi.org/10.1093/jnen/nlz060.
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  - Harrison, William T., Thomas Bouldin, Anne Buckley, Januario Estrada, Roger McLendon, and Kimberly Janssen. “Sudden Unexpected Death in a Child From an Anaplastic Ependymoma.” Am J Forensic Med Pathol 40, no. 3 (September 2019): 275–78. https://doi.org/10.1097/PAF.0000000000000480.
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  - Hansen, Landon J., Ran Sun, Rui Yang, Simranjit X. Singh, Lee H. Chen, Christopher J. Pirozzi, Casey J. Moure, et al. “MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation.” Cancer Res 79, no. 13 (July 1, 2019): 3383–94. https://doi.org/10.1158/0008-5472.CAN-18-1010.
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  - Diplas, Bill H., Heng Liu, Rui Yang, Landon J. Hansen, Alexis L. Zachem, Fangping Zhao, Darell D. Bigner, et al. “Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.” Neuro Oncol 21, no. 4 (March 18, 2019): 440–50. https://doi.org/10.1093/neuonc/noy167.
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  - Lehman, Norman L., Aisulu Usubalieva, Tong Lin, Sariah J. Allen, Quynh T. Tran, Bret C. Mobley, Roger E. McLendon, et al. “Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.” Acta Neuropathol Commun 7, no. 1 (March 15, 2019): 42. https://doi.org/10.1186/s40478-019-0689-3.
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  - Hoeman, Christine M., Francisco J. Cordero, Guo Hu, Katie Misuraca, Megan M. Romero, Herminio J. Cardona, Javad Nazarian, et al. “ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.” Nat Commun 10, no. 1 (March 4, 2019): 1023. https://doi.org/10.1038/s41467-019-08823-9.
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  - Tan, Char Loo, Yin Huei Pang, Keith Hsiu Chin Lim, Lwin Sein, Patrick J. Codd, and Roger E. McLendon. “Two Extraordinary Sellar Neuronal Tumors: Literature Review and Comparison of Clinicopathologic Features.” Am J Clin Pathol 151, no. 3 (February 4, 2019): 241–54. https://doi.org/10.1093/ajcp/aqy155.
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  - Ahn, Janice S., William Harrison, Elin Hughes, and Roger E. McLendon. “Intraventricular Pilocytic Astrocytoma With KIAA1549/BRAF Fusion Arising in a 44-Year Old.” J Neuropathol Exp Neurol 78, no. 2 (February 1, 2019): 187–90. https://doi.org/10.1093/jnen/nly116.
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  - Batich, Kristen A., Richard F. Riedel, John P. Kirkpatrick, Betty C. Tong, William C. Eward, Char Loo Tan, Patricia D. Pittman, Roger E. McLendon, and Katherine B. Peters. “Recurrent Extradural Myxopapillary Ependymoma With Oligometastatic Spread.” Front Oncol 9 (2019): 1322. https://doi.org/10.3389/fonc.2019.01322.
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  - Lipp, Eric S., Patrick Healy, Alan Austin, Alysha Clark, Tara Dalton, Kathryn Perkinson, James E. Herndon, et al. “MGMT: Immunohistochemical Detection in High-Grade Astrocytomas.” J Neuropathol Exp Neurol 78, no. 1 (January 1, 2019): 57–64. https://doi.org/10.1093/jnen/nly110.
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  - Shen, Erica, Margaret O. Johnson, Jessica W. Lee, Eric S. Lipp, Dina M. Randazzo, Annick Desjardins, Roger E. McLendon, et al. “Performance of a nomogram for IDH-wild-type glioblastoma patient survival in an elderly cohort.” Neurooncol Adv 1, no. 1 (2019): vdz036. https://doi.org/10.1093/noajnl/vdz036.
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  - Lipp, Eric S., and Roger E. McLendon. “Tissue is the Issue: Biomarkers of Prognosis and Classification in Adult Gliomas.” Semin Oncol Nurs 34, no. 5 (December 2018): 430–42. https://doi.org/10.1016/j.soncn.2018.10.002.
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  - Atik, Ahmet F., Carter M. Suryadevara, Ryan M. Schweller, Jennifer L. West, Patrick Healy, James E. Herndon Ii, Kendra L. Congdon, et al. “Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells.” J Clin Neurosci 56 (October 2018): 163–68. https://doi.org/10.1016/j.jocn.2018.06.005.
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  - Tan, Char Loo, Balamurugan Vellayappan, Bingcheng Wu, Tseng Tsai Yeo, and Roger E. McLendon. “Molecular profiling of different glioma specimens from an Ollier disease patient suggests a multifocal disease process in the setting of IDH mosaicism.” Brain Tumor Pathol 35, no. 4 (October 2018): 202–8. https://doi.org/10.1007/s10014-018-0327-y.
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  - Tan, Char-Loo, Daniel Landi, Herbert Fuchs, and Roger E. McLendon. “Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up.” Neuropathology 38, no. 5 (October 2018): 542–48. https://doi.org/10.1111/neup.12502.
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  - Tan, Char Loo, Miriam Santiago Kimpo, Vincent Diong Weng Nga, Kok Siong Poon, and Roger E. McLendon. “Intracerebral Flexner-Wintersteiner Rosette-Rich Tumor With Somatic RB1 Mutation: A CNS Embryonal Tumor With Retinoblastic Differentiation.” J Neuropathol Exp Neurol 77, no. 9 (September 1, 2018): 846–52. https://doi.org/10.1093/jnen/nly062.
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  - Cavalli, Florence M. G., Jens-Martin Hübner, Tanvi Sharma, Betty Luu, Martin Sill, Michal Zapotocky, Stephen C. Mack, et al. “Heterogeneity within the PF-EPN-B ependymoma subgroup.” Acta Neuropathol 136, no. 2 (August 2018): 227–37. https://doi.org/10.1007/s00401-018-1888-x.
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  - Gedeon, Patrick C., Teilo H. Schaller, Satish K. Chitneni, Bryan D. Choi, Chien-Tsun Kuan, Carter M. Suryadevara, David J. Snyder, et al. “A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma.” Clin Cancer Res 24, no. 15 (August 1, 2018): 3611–31. https://doi.org/10.1158/1078-0432.CCR-17-0126.
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  - Thompson, Eric M., Michael Brown, Elena Dobrikova, Vijay Ramaswamy, Michael D. Taylor, Roger McLendon, Jennifer Sanks, Vidya Chandramohan, Darell Bigner, and Matthias Gromeier. “Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.” J Neuropathol Exp Neurol 77, no. 8 (August 1, 2018): 696–702. https://doi.org/10.1093/jnen/nly045.
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  - Desjardins, Annick, Matthias Gromeier, James E. Herndon, Nike Beaubier, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, et al. “Recurrent Glioblastoma Treated with Recombinant Poliovirus.” N Engl J Med 379, no. 2 (July 12, 2018): 150–61. https://doi.org/10.1056/NEJMoa1716435.
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  - Ricketts, Christopher J., Aguirre A. De Cubas, Huihui Fan, Christof C. Smith, Martin Lang, Ed Reznik, Reanne Bowlby, et al. “The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.” Cell Rep 23, no. 12 (June 19, 2018): 3698. https://doi.org/10.1016/j.celrep.2018.06.032.
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  - Diplas, Bill H., Xujun He, Jacqueline A. Brosnan-Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, et al. “The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.” Nat Commun 9, no. 1 (May 25, 2018): 2087. https://doi.org/10.1038/s41467-018-04448-6.
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  - Thorsson, Vésteinn, David L. Gibbs, Scott D. Brown, Denise Wolf, Dante S. Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, et al. “The Immune Landscape of Cancer.” Immunity 48, no. 4 (April 17, 2018): 812-830.e14. https://doi.org/10.1016/j.immuni.2018.03.023.
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  - Berger, Ashton C., Anil Korkut, Rupa S. Kanchi, Apurva M. Hegde, Walter Lenoir, Wenbin Liu, Yuexin Liu, et al. “A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.” Cancer Cell 33, no. 4 (April 9, 2018): 690-705.e9. https://doi.org/10.1016/j.ccell.2018.03.014.
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  - Liu, Yang, Nilay S. Sethi, Toshinori Hinoue, Barbara G. Schneider, Andrew D. Cherniack, Francisco Sanchez-Vega, Jose A. Seoane, et al. “Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.” Cancer Cell 33, no. 4 (April 9, 2018): 721-735.e8. https://doi.org/10.1016/j.ccell.2018.03.010.
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  - Taylor, Alison M., Juliann Shih, Gavin Ha, Galen F. Gao, Xiaoyang Zhang, Ashton C. Berger, Steven E. Schumacher, et al. “Genomic and Functional Approaches to Understanding Cancer Aneuploidy.” Cancer Cell 33, no. 4 (April 9, 2018): 676-689.e3. https://doi.org/10.1016/j.ccell.2018.03.007.
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  - Wang, Zehua, Bo Yang, Min Zhang, Weiwei Guo, Zhiyuan Wu, Yue Wang, Lin Jia, et al. “lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.” Cancer Cell 33, no. 4 (April 9, 2018): 706-720.e9. https://doi.org/10.1016/j.ccell.2018.03.006.
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  - Bailey, Matthew H., Collin Tokheim, Eduard Porta-Pardo, Sohini Sengupta, Denis Bertrand, Amila Weerasinghe, Antonio Colaprico, et al. “Comprehensive Characterization of Cancer Driver Genes and Mutations.” Cell 173, no. 2 (April 5, 2018): 371-385.e18. https://doi.org/10.1016/j.cell.2018.02.060.
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  - Chen, Han, Chunyan Li, Xinxin Peng, Zhicheng Zhou, John N. Weinstein, John N. Cancer Genome Atlas Research Network, and Han Liang. “A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.” Cell 173, no. 2 (April 5, 2018): 386-399.e12. https://doi.org/10.1016/j.cell.2018.03.027.
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  - Ding, Li, Matthew H. Bailey, Eduard Porta-Pardo, Vesteinn Thorsson, Antonio Colaprico, Denis Bertrand, David L. Gibbs, et al. “Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.” Cell 173, no. 2 (April 5, 2018): 305-320.e10. https://doi.org/10.1016/j.cell.2018.03.033.
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  - Hoadley, Katherine A., Christina Yau, Toshinori Hinoue, Denise M. Wolf, Alexander J. Lazar, Esther Drill, Ronglai Shen, et al. “Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.” Cell 173, no. 2 (April 5, 2018): 291-304.e6. https://doi.org/10.1016/j.cell.2018.03.022.
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  - Huang, Kuan-Lin, R Jay Mashl, Yige Wu, Deborah I. Ritter, Jiayin Wang, Clara Oh, Marta Paczkowska, et al. “Pathogenic Germline Variants in 10,389 Adult Cancers.” Cell 173, no. 2 (April 5, 2018): 355-370.e14. https://doi.org/10.1016/j.cell.2018.03.039.
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  - Liu, Jianfang, Tara Lichtenberg, Katherine A. Hoadley, Laila M. Poisson, Alexander J. Lazar, Andrew D. Cherniack, Albert J. Kovatich, et al. “An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.” Cell 173, no. 2 (April 5, 2018): 400-416.e11. https://doi.org/10.1016/j.cell.2018.02.052.
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  - Malta, Tathiane M., Artem Sokolov, Andrew J. Gentles, Tomasz Burzykowski, Laila Poisson, John N. Weinstein, Bożena Kamińska, et al. “Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.” Cell 173, no. 2 (April 5, 2018): 338-354.e15. https://doi.org/10.1016/j.cell.2018.03.034.
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  - Sanchez-Vega, Francisco, Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor C. La, Sofia Dimitriadoy, et al. “Oncogenic Signaling Pathways in The Cancer Genome Atlas.” Cell 173, no. 2 (April 5, 2018): 321-337.e10. https://doi.org/10.1016/j.cell.2018.03.035.
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  - Campbell, Joshua D., Christina Yau, Reanne Bowlby, Yuexin Liu, Kevin Brennan, Huihui Fan, Alison M. Taylor, et al. “Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.” Cell Rep 23, no. 1 (April 3, 2018): 194-212.e6. https://doi.org/10.1016/j.celrep.2018.03.063.
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  - Chiu, Hua-Sheng, Sonal Somvanshi, Ektaben Patel, Ting-Wen Chen, Vivek P. Singh, Barry Zorman, Sagar L. Patil, et al. “Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context.” Cell Rep 23, no. 1 (April 3, 2018): 297-312.e12. https://doi.org/10.1016/j.celrep.2018.03.064.
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  - Gao, Qingsong, Wen-Wei Liang, Steven M. Foltz, Gnanavel Mutharasu, Reyka G. Jayasinghe, Song Cao, Wen-Wei Liao, et al. “Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.” Cell Rep 23, no. 1 (April 3, 2018): 227-238.e3. https://doi.org/10.1016/j.celrep.2018.03.050.
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  - Ge, Zhongqi, Jake S. Leighton, Yumeng Wang, Xinxin Peng, Zhongyuan Chen, Hu Chen, Yutong Sun, et al. “Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.” Cell Rep 23, no. 1 (April 3, 2018): 213-226.e3. https://doi.org/10.1016/j.celrep.2018.03.047.
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  - Jayasinghe, Reyka G., Song Cao, Qingsong Gao, Michael C. Wendl, Nam Sy Vo, Sheila M. Reynolds, Yanyan Zhao, et al. “Systematic Analysis of Splice-Site-Creating Mutations in Cancer.” Cell Rep 23, no. 1 (April 3, 2018): 270-281.e3. https://doi.org/10.1016/j.celrep.2018.03.052.
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  - Knijnenburg, Theo A., Linghua Wang, Michael T. Zimmermann, Nyasha Chambwe, Galen F. Gao, Andrew D. Cherniack, Huihui Fan, et al. “Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.” Cell Rep 23, no. 1 (April 3, 2018): 239-254.e6. https://doi.org/10.1016/j.celrep.2018.03.076.
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  - Kuan, Chien-Tsun, Carol J. Wikstrand, Roger E. McLendon, Michael R. Zalutsky, Ujendra Kumar, and Darell D. Bigner. “Detection of amino-terminal extracellular domain of somatostatin receptor 2 by specific monoclonal antibodies and quantification of receptor density in medulloblastoma.” Hybridoma (Larchmt) 28, no. 6 (December 2009): 389–403. https://doi.org/10.1089/hyb.2009.0049.
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  - Lu, Zheming, Lei Zhou, Patrick Killela, Ahmed B. Rasheed, Chunhui Di, William E. Poe, Roger E. McLendon, Darell D. Bigner, Christopher Nicchitta, and Hai Yan. “Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress.” Cancer Res 69, no. 23 (December 1, 2009): 9105–11. https://doi.org/10.1158/0008-5472.CAN-09-2775.
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  - Quinn, Jennifer A., Sara Xiaoyin Jiang, David A. Reardon, Annick Desjardins, James J. Vredenburgh, Allan H. Friedman, John H. Sampson, Roger E. McLendon, James E. Herndon, and Henry S. Friedman. “Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.” J Neurooncol 95, no. 3 (December 2009): 393–400. https://doi.org/10.1007/s11060-009-9937-x.
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  - Heddleston, John M., Zhizhong Li, Roger E. McLendon, Anita B. Hjelmeland, and Jeremy N. Rich. “The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype.” Cell Cycle 8, no. 20 (October 15, 2009): 3274–84. https://doi.org/10.4161/cc.8.20.9701.
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  - Choi, Bryan D., Gary E. Archer, Duane A. Mitchell, Amy B. Heimberger, Roger E. McLendon, Darell D. Bigner, and John H. Sampson. “EGFRvIII-targeted vaccination therapy of malignant glioma.” Brain Pathol 19, no. 4 (October 2009): 713–23. https://doi.org/10.1111/j.1750-3639.2009.00318.x.
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  - Jeuken, Judith, Angelique Sijben, Cristina Alenda, Jos Rijntjes, Marieke Dekkers, Sandra Boots-Sprenger, Roger McLendon, and Pieter Wesseling. “Robust detection of EGFR copy number changes and EGFR variant III: technical aspects and relevance for glioma diagnostics.” Brain Pathol 19, no. 4 (October 2009): 661–71. https://doi.org/10.1111/j.1750-3639.2009.00320.x.
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  - Quinn, Jennifer A., Sara Xiaoyin Jiang, David A. Reardon, Annick Desjardins, James J. Vredenburgh, Jeremy N. Rich, Sridharan Gururangan, et al. “Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.” Neuro Oncol 11, no. 5 (October 2009): 556–61. https://doi.org/10.1215/15228517-2009-007.
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  - Wang, Hui, Justin D. Lathia, Qiulian Wu, Jialiang Wang, Zhizhong Li, John M. Heddleston, Christine E. Eyler, et al. “Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth.” Stem Cells 27, no. 10 (October 2009): 2393–2404. https://doi.org/10.1002/stem.188.
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  - Read, T. A., M. P. Fogarty, S. L. Markant, R. E. McLendon, Z. Wei, D. W. Ellison, P. G. Febbo, and R. J. Wechsler-Reya. “Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma (DOI:10.1016/j.ccr.2008.12.016).” Cancer Cell 16, no. 3 (September 8, 2009): 267. https://doi.org/10.1016/j.ccr.2009.08.009.
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  - Boskovitz, Abraham, Roger E. McLendon, Tatsunori Okamura, John H. Sampson, Darell D. Bigner, and Michael R. Zalutsky. “Treatment of HER2-positive breast carcinomatous meningitis with intrathecal administration of alpha-particle-emitting (211)At-labeled trastuzumab.” Nucl Med Biol 36, no. 6 (August 2009): 659–69. https://doi.org/10.1016/j.nucmedbio.2009.04.003.
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  - Horbinski, Craig, Sanja Dacic, Roger E. McLendon, Kathy Cieply, Michael Datto, Daniel J. Brat, and Charleen T. Chu. “Chordoid glioma: a case report and molecular characterization of five cases.” Brain Pathol 19, no. 3 (July 2009): 439–48. https://doi.org/10.1111/j.1750-3639.2008.00196.x.
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  - Quinn, Jennifer A., Sara Xiaoyin Jiang, David A. Reardon, Annick Desjardins, James J. Vredenburgh, Sridharan Gururangan, John H. Sampson, Roger E. McLendon, James E. Herndon, and Henry S. Friedman. “Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.” Cancer 115, no. 13 (July 1, 2009): 2964–70. https://doi.org/10.1002/cncr.24336.
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  - Li, Zhizhong, Shideng Bao, Qiulian Wu, Hui Wang, Christine Eyler, Sith Sathornsumetee, Qing Shi, et al. “Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells.” Cancer Cell 15, no. 6 (June 2, 2009): 501–13. https://doi.org/10.1016/j.ccr.2009.03.018.
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  - Archer, Gary E., Amy B. Heimberger, Darell D. Bigner, Tom Davis, Henry S. Friedman, Tibor Keler, Roger E. McLendon, et al. “INDUCTION OF IMMUNOLOGIC AND CLINICAL RESPONSES WITH EGFRVIII-TARGETED VACCINE (CDX-110) WITH CYCLES OF TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED EGFRVIII-POSITIVE GBM.” Neuro Oncology 11, no. 2 (April 1, 2009): 224–224.
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  - Kuan, Chien-Tsun, Kenji Wakiya, James E. Herndon, Carol J. Wikstrand, Roger E. McLendon, Michael R. Zalutsky, Ira H. Pastan, and Darell D. Bigner. “RECOMBINANT ANTIBODY-BASED MOLECULAR THERAPEUTICS FOR BRAIN TUMOR IMMUNOTHERAPY.” Neuro Oncology 11, no. 2 (April 1, 2009): 224–224.
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  - Quinn, Jennifer A., Sara Xiaoyin Jiang, David A. Reardon, Annick Desjardins, James J. Vredenburgh, Jeremy N. Rich, Sridharan Gururangan, et al. “Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.” J Clin Oncol 27, no. 8 (March 10, 2009): 1262–67. https://doi.org/10.1200/JCO.2008.18.8417.
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  - Yan, Hai, D Williams Parsons, Genglin Jin, Roger McLendon, B Ahmed Rasheed, Weishi Yuan, Ivan Kos, et al. “IDH1 and IDH2 mutations in gliomas.” N Engl J Med 360, no. 8 (February 19, 2009): 765–73. https://doi.org/10.1056/NEJMoa0808710.
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  - Read, Tracy-Ann, Marie P. Fogarty, Shirley L. Markant, Roger E. McLendon, Zhengzheng Wei, David W. Ellison, Phillip G. Febbo, and Robert J. Wechsler-Reya. “Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.” Cancer Cell 15, no. 2 (February 3, 2009): 135–47. https://doi.org/10.1016/j.ccr.2008.12.016.
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  - Quinn, Jennifer A., Sara Xiaoyin Jiang, James Carter, David A. Reardon, Annick Desjardins, James J. Vredenburgh, Jeremy N. Rich, et al. “Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme.” Clin Cancer Res 15, no. 3 (February 1, 2009): 1064–68. https://doi.org/10.1158/1078-0432.CCR-08-2130.
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  - Waldau, Ben, Roger E. McLendon, Herbert E. Fuchs, Timothy M. George, and Gerald A. Grant. “Few isolated neurons in hypothalamic hamartomas may cause gelastic seizures.” Pediatr Neurosurg 45, no. 3 (2009): 225–29. https://doi.org/10.1159/000224620.
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  - Eyler, Christine E., Wen-Chi Foo, Katherine M. LaFiura, Roger E. McLendon, Anita B. Hjelmeland, and Jeremy N. Rich. “Brain cancer stem cells display preferential sensitivity to Akt inhibition.” Stem Cells 26, no. 12 (December 2008): 3027–36. https://doi.org/10.1634/stemcells.2007-1073.
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  - Cancer Genome Atlas Research Network, Elizabeth. “Comprehensive genomic characterization defines human glioblastoma genes and core pathways.” Nature 455, no. 7216 (October 23, 2008): 1061–68. https://doi.org/10.1038/nature07385.
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  - Gururangan, Sridharan, Jeanne Krauser, Melody A. Watral, Tim Driscoll, Nicole Larrier, David A. Reardon, Jeremy N. Rich, et al. “Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.” Neuro Oncol 10, no. 5 (October 2008): 745–51. https://doi.org/10.1215/15228517-2008-044.
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  - Ray, Gregory T., Shanti S. Agarwal, and Roger E. McLendon. “A recurrent cerebellar lesion in a young boy.” Brain Pathol 18, no. 4 (October 2008): 623–27. https://doi.org/10.1111/j.1750-3639.2008.00216.x.
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  - Parsons, D Williams, Siân Jones, Xiaosong Zhang, Jimmy Cheng-Ho Lin, Rebecca J. Leary, Philipp Angenendt, Parminder Mankoo, et al. “An integrated genomic analysis of human glioblastoma multiforme.” Science 321, no. 5897 (September 26, 2008): 1807–12. https://doi.org/10.1126/science.1164382.
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  - Bao, Shideng, Qiulian Wu, Zhizhong Li, Sith Sathornsumetee, Hui Wang, Roger E. McLendon, Anita B. Hjelmeland, and Jeremy N. Rich. “Targeting cancer stem cells through L1CAM suppresses glioma growth.” Cancer Res 68, no. 15 (August 1, 2008): 6043–48. https://doi.org/10.1158/0008-5472.CAN-08-1079.
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  - Maxwell, Jill A., Stewart P. Johnson, Roger E. McLendon, David W. Lister, Krystle S. Horne, Ahmed Rasheed, Jennifer A. Quinn, et al. “Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.” Clin Cancer Res 14, no. 15 (August 1, 2008): 4859–68. https://doi.org/10.1158/1078-0432.CCR-07-4807.
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  - Brat, Daniel J., Joseph E. Parisi, Bette K. Kleinschmidt-DeMasters, Anthony T. Yachnis, Thomas J. Montine, Philip J. Boyer, Suzanne Z. Powell, Richard A. Prayson, Roger E. McLendon, and Roger E. Neuropathology Committee, College of American Pathologists. “Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition.” Arch Pathol Lab Med 132, no. 6 (June 2008): 993–1007. https://doi.org/10.5858/2008-132-993-SNUARO.
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  - McLendon, R. E. “Re: Axonal injury in head injuries with very short survival.” Neuropathol Appl Neurobiol 34, no. 3 (June 2008): 371. https://doi.org/10.1111/j.1365-2990.2008.00942.x.
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  - Parisi, Joseph E., Dylan V. Miller, Philip J. Boyer, Daniel J. Brat, Elizabeth J. Cochran, Mark L. Cohen, Bette K. Demasters, et al. “Protocol for the examination of specimens from patients with tumors of the brain/spinal cord.” Arch Pathol Lab Med 132, no. 6 (June 2008): 907–12. https://doi.org/10.5858/2008-132-907-PFTEOS.
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  - Reardon, David A., Annick Desjardins, James J. Vredenburgh, Sith Sathornsumetee, Jeremy N. Rich, Jennifer A. Quinn, Theodore F. Lagattuta, et al. “Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.” Neuro Oncol 10, no. 3 (June 2008): 330–40. https://doi.org/10.1215/15228517-2008-003.
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  - Sampson, John H., Gamal Akabani, Gerald E. Archer, Mitchel S. Berger, R Edward Coleman, Allan H. Friedman, Henry S. Friedman, et al. “Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.” Neuro Oncol 10, no. 3 (June 2008): 320–29. https://doi.org/10.1215/15228517-2008-012.
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  - Reardon, David A., Michael R. Zalutsky, Gamal Akabani, R Edward Coleman, Allan H. Friedman, James E. Herndon, Roger E. McLendon, et al. “A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.” Neuro Oncol 10, no. 2 (April 2008): 182–89. https://doi.org/10.1215/15228517-2007-053.
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  - Davis, Faith G., Beatrice S. Malmer, Ken Aldape, Jill S. Barnholtz-Sloan, Melissa L. Bondy, Thomas Brännström, Janet M. Bruner, et al. “Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology Consortium.” Cancer Epidemiol Biomarkers Prev 17, no. 3 (March 2008): 484–89. https://doi.org/10.1158/1055-9965.EPI-07-0725.
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  - Mitchell, Duane A., Weihua Xie, Robert Schmittling, Chris Learn, Allan Friedman, Roger E. McLendon, and John H. Sampson. “Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma.” Neuro Oncol 10, no. 1 (February 2008): 10–18. https://doi.org/10.1215/15228517-2007-035.
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  - Kovacs, Kalman, Bernd W. Scheithauer, Matilde Lombardero, Roger E. McLendon, Luis V. Syro, Humberto Uribe, Leon D. Ortiz, and Luis C. Penagos. “MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy.” Acta Neuropathol 115, no. 2 (February 2008): 261–62. https://doi.org/10.1007/s00401-007-0279-5.
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  - Mott, Ryan T., Kristi C. Turner, Darell D. Bigner, and Roger E. McLendon. “Utility of EGFR and PTEN numerical aberrations in the evaluation of diffusely infiltrating astrocytomas. Laboratory investigation.” J Neurosurg 108, no. 2 (February 2008): 330–35. https://doi.org/10.3171/JNS/2008/108/2/0330.
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  - Sathornsumetee, Sith, Yiting Cao, Jennifer E. Marcello, James E. Herndon, Roger E. McLendon, Annick Desjardins, Henry S. Friedman, Mark W. Dewhirst, James J. Vredenburgh, and Jeremy N. Rich. “Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan.” J Clin Oncol 26, no. 2 (January 10, 2008): 271–78. https://doi.org/10.1200/JCO.2007.13.3652.
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  - Abou-Donia, Mohamed B., Eman M. El-Masry, Ali A. Abdel-Rahman, Roger E. McLendon, and Susan S. Schiffman. “Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats.” J Toxicol Environ Health A 71, no. 21 (2008): 1415–29. https://doi.org/10.1080/15287390802328630.
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  - Hasselblatt, Martin, Astrid Jeibmann, Meri Guerry, Volker Senner, Werner Paulus, and Roger E. McLendon. “Choroid plexus papilloma with neuropil-like islands.” Am J Surg Pathol 32, no. 1 (January 2008): 162–66. https://doi.org/10.1097/PAS.0b013e3180cc2015.
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  - Wang, Jialiang, Hui Wang, Zhizhong Li, Qiulian Wu, Justin D. Lathia, Roger E. McLendon, Anita B. Hjelmeland, and Jeremy N. Rich. “c-Myc is required for maintenance of glioma cancer stem cells.” Plos One 3, no. 11 (2008): e3769. https://doi.org/10.1371/journal.pone.0003769.
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  - Zalutsky, Michael R., David A. Reardon, Gamal Akabani, R Edward Coleman, Allan H. Friedman, Henry S. Friedman, Roger E. McLendon, Terence Z. Wong, and Darell D. Bigner. “Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6.” J Nucl Med 49, no. 1 (January 2008): 30–38. https://doi.org/10.2967/jnumed.107.046938.
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  - McLendon, Roger E., Kristi Turner, Kathryn Perkinson, and Jeremy Rich. “Second messenger systems in human gliomas.” Arch Pathol Lab Med 131, no. 10 (October 2007): 1585–90. https://doi.org/10.5858/2007-131-1585-SMSIHG.
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  - Wagner, Lars M., Roger E. McLendon, K Jin Yoon, Brian D. Weiss, Catherine A. Billups, and Mary K. Danks. “Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma.” Clin Cancer Res 13, no. 18 Pt 1 (September 15, 2007): 5418–25. https://doi.org/10.1158/1078-0432.CCR-07-0418.
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  - Desjardins, Annick, Jennifer A. Quinn, James J. Vredenburgh, Sith Sathornsumetee, Allan H. Friedman, James E. Herndon, Roger E. McLendon, et al. “Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas.” J Neurooncol 83, no. 1 (May 2007): 53–60. https://doi.org/10.1007/s11060-006-9302-2.
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  - McLendon, Roger E., Gamal Akabani, Henry S. Friedman, David A. Reardon, Linda Cleveland, Ilkcan Cokgor, James E. Herndon, et al. “Tumor resection cavity administered iodine-131-labeled antitenascin 81C6 radioimmunotherapy in patients with malignant glioma: neuropathology aspects.” Nucl Med Biol 34, no. 4 (May 2007): 405–13. https://doi.org/10.1016/j.nucmedbio.2007.01.009.
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  - Grunkemeier, M Natalie, Kristi Turner, and Roger E. McLendon. “Recurrent glioblastoma diagnosed by fluorescence in situ hybridization for EGFR.” Acta Neuropathol 113, no. 2 (February 2007): 217–19. https://doi.org/10.1007/s00401-006-0175-4.
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  - Powers, Ciaran J., Kent C. New, Roger E. McLendon, Allan H. Friedman, and Herbert E. Fuchs. “Cerebellopontine angle craniopharyngioma: case report and literature review.” Pediatr Neurosurg 43, no. 2 (2007): 158–63. https://doi.org/10.1159/000098394.
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  - Bao, Shideng, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hjelmeland, Mark W. Dewhirst, Darell D. Bigner, and Jeremy N. Rich. “Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.” Nature 444, no. 7120 (December 7, 2006): 756–60. https://doi.org/10.1038/nature05236.
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  - Fouladi, Maryam, Susan M. Blaney, Tina Young Poussaint, Burgess B. Freeman, Roger McLendon, Christine Fuller, Adekunle M. Adesina, et al. “Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study.” Cancer 107, no. 9 (November 1, 2006): 2291–97. https://doi.org/10.1002/cncr.22241.
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  - Ryan, Christopher W., M Eileen Dolan, Bruce B. Brockstein, Roger McLendon, Shannon M. Delaney, Brian L. Samuels, Edem S. Agamah, and Everett E. Vokes. “A phase II trial of O6-benzylguanine and carmustine in patients with advanced soft tissue sarcoma.” Cancer Chemother Pharmacol 58, no. 5 (November 2006): 634–39. https://doi.org/10.1007/s00280-006-0210-0.
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  - Maxwell, Jill A., Stewart P. Johnson, Jennifer A. Quinn, Roger E. McLendon, Francis Ali-Osman, Allan H. Friedman, James E. Herndon, et al. “Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.” Mol Cancer Ther 5, no. 10 (October 2006): 2531–39. https://doi.org/10.1158/1535-7163.MCT-06-0106.
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  - Ochiai, Hidenobu, Chris T. Pernell, Gary E. Archer, Tracy A. Chewning, Roger E. McLendon, Henry S. Friedman, and John H. Sampson. “Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin.” Neurol Med Chir (Tokyo) 46, no. 10 (October 2006): 485–89. https://doi.org/10.2176/nmc.46.485.
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  - Reardon, D. A., M. R. Zalutsky, G. Akabani, R. E. Coleman, A. H. Friedman, R. E. McLendon, H. S. Friedman, J. E. Herndon, J. Kirkpatrick, and D. D. Bigner. “Radioimmunotherapy of patients with malignant brain tumors: patient-specific dosing of I-131-labeled anti-tenacin antibody to achieve 44 Gy boost dose to resection cavity margins.” European Journal of Nuclear Medicine and Molecular Imaging 33 (September 1, 2006): S194–S194.
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  - Sathornsumetee, Sith, Anita B. Hjelmeland, Stephen T. Keir, Roger E. McLendon, David Batt, Timothy Ramsey, Naeem Yusuff, et al. “AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.” Cancer Res 66, no. 17 (September 1, 2006): 8722–30. https://doi.org/10.1158/0008-5472.CAN-06-0284.
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  - Zalutsky, M. R., D. A. Reardon, J. A. Quinn, R. E. Coleman, G. Akabani, A. H. Friedman, H. S. Friedman, et al. “Chimeric murine/human IgG(2) anti-tenascin 81C6 monoclonal antibody: phase I trial in patients with malignant glioma of a construct with improved stability.” European Journal of Nuclear Medicine and Molecular Imaging 33 (September 1, 2006): S194–S194.
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  - Bao, Shideng, Qiulian Wu, Sith Sathornsumetee, Yueling Hao, Zhizhong Li, Anita B. Hjelmeland, Qing Shi, Roger E. McLendon, Darell D. Bigner, and Jeremy N. Rich. “Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.” Cancer Res 66, no. 16 (August 15, 2006): 7843–48. https://doi.org/10.1158/0008-5472.CAN-06-1010.
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  - Reardon, David A., Jennifer A. Quinn, Gamal Akabani, R Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, et al. “Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results.” J Nucl Med 47, no. 6 (June 2006): 912–18.
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  - McLendon, Roger E. “Errors in surgical neuropathology and the influence of cognitive biases: the psychology of intelligence analysis.” Arch Pathol Lab Med 130, no. 5 (May 2006): 613–16. https://doi.org/10.5858/2006-130-613-EISNAT.
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  - Chintagumpala, Murali M., Henry S. Friedman, Clinton F. Stewart, James Kepner, Roger E. McLendon, Paul L. Modrich, Charles McCluggage, et al. “A phase II window trial of procarbazine and topotecan in children with high-grade glioma: a report from the children's oncology group.” J Neurooncol 77, no. 2 (April 2006): 193–98. https://doi.org/10.1007/s11060-005-9024-x.
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  - Reardon, David A., Jennifer A. Quinn, James J. Vredenburgh, Sridharan Gururangan, Allan H. Friedman, Annick Desjardins, Sith Sathornsumetee, et al. “Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma.” Clin Cancer Res 12, no. 3 Pt 1 (February 1, 2006): 860–68. https://doi.org/10.1158/1078-0432.CCR-05-2215.
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  - Reardon, David A., Gamal Akabani, R Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, Roger E. McLendon, et al. “Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results.” J Clin Oncol 24, no. 1 (January 1, 2006): 115–22. https://doi.org/10.1200/JCO.2005.03.4082.
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  - Reardon, David A., Merrill J. Egorin, Jennifer A. Quinn, Jeremy N. Rich, Sridharan Gururangan, James J. Vredenburgh, Annick Desjardins, et al. “Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme.” J Clin Oncol 23, no. 36 (December 20, 2005): 9359–68. https://doi.org/10.1200/JCO.2005.03.2185.
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  - Friedman, A. H., R. E. McLendon, J. N. Provenzale, and H. S. Friedman. “Ependymoma,” December 1, 2005, 190–98. https://doi.org/10.1016/B978-0-7216-8148-1.50028-0.
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  - Rich, Jeremy N., Sith Sathornsumetee, Stephen T. Keir, Mark W. Kieran, Andrea Laforme, Arja Kaipainen, Roger E. McLendon, et al. “ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors.” Clin Cancer Res 11, no. 22 (November 15, 2005): 8145–57. https://doi.org/10.1158/1078-0432.CCR-05-0319.
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  - McLendon, Roger E., James E. Herndon, Bryan West, David Reardon, Rodney Wiltshire, BK Ahmed Rasheed, Jennifer Quinn, Henry S. Friedman, Allan H. Friedman, and Darell D. Bigner. “Survival analysis of presumptive prognostic markers among oligodendrogliomas.” Cancer 104, no. 8 (October 15, 2005): 1693–99. https://doi.org/10.1002/cncr.21362.
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  - Quinn, Jennifer A., Annick Desjardins, Jon Weingart, Henry Brem, M Eileen Dolan, Shannon M. Delaney, James Vredenburgh, et al. “Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.” J Clin Oncol 23, no. 28 (October 1, 2005): 7178–87. https://doi.org/10.1200/JCO.2005.06.502.
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  - Reardon, David A., Jennifer A. Quinn, Jeremy N. Rich, Annick Desjardins, James Vredenburgh, Sridharan Gururangan, Sith Sathornsumetee, et al. “Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.” Cancer 104, no. 7 (October 1, 2005): 1478–86. https://doi.org/10.1002/cncr.21316.
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  - Akabani, Gamal, David A. Reardon, R Edward Coleman, Terence Z. Wong, Scott D. Metzler, James E. Bowsher, Daniel P. Barboriak, et al. “Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study.” J Nucl Med 46, no. 6 (June 2005): 1042–51.
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  - Rich, Jeremy N., Christopher Hans, Beatrix Jones, Edwin S. Iversen, Roger E. McLendon, BK Ahmed Rasheed, Adrian Dobra, et al. “Gene expression profiling and genetic markers in glioblastoma survival.” Cancer Res 65, no. 10 (May 15, 2005): 4051–58. https://doi.org/10.1158/0008-5472.CAN-04-3936.
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  - Crain, Barbara J., Sebastian R. Alston, Leslie A. Bruch, Ronald L. Hamilton, Roger E. McLendon, C Harker Rhodes, Tarik Tihan, and Karen M. Weidenheim. “Accreditation council for graduate medical education (ACGME) competencies in neuropathology training.” J Neuropathol Exp Neurol 64, no. 4 (April 2005): 273–79. https://doi.org/10.1093/jnen/64.4.273.
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  - Di, Chunhui, Shaoxi Liao, David C. Adamson, Timothy J. Parrett, Daniel K. Broderick, Qun Shi, Christoph Lengauer, et al. “Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.” Cancer Res 65, no. 3 (February 1, 2005): 919–24.
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  - Sampson, John H., David A. Reardon, Allan H. Friedman, Henry S. Friedman, R Edward Coleman, Roger E. McLendon, Ira Pastan, and Darell D. Bigner. “Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study.” Neuro Oncol 7, no. 1 (January 2005): 90–96. https://doi.org/10.1215/S1152851703000589.
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  - Goudar, Ranjit K., Qing Shi, Mark D. Hjelmeland, Stephen T. Keir, Roger E. McLendon, Carol J. Wikstrand, Elizabeth D. Reese, et al. “Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.” Mol Cancer Ther 4, no. 1 (January 2005): 101–12.
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  - Broderick, Daniel K., Chunhui Di, Timothy J. Parrett, Yardena R. Samuels, Jordan M. Cummins, Roger E. McLendon, Daniel W. Fults, Victor E. Velculescu, Darell D. Bigner, and Hai Yan. “Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas.” Cancer Res 64, no. 15 (August 1, 2004): 5048–50. https://doi.org/10.1158/0008-5472.CAN-04-1170.
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  - Wiltshire, Rodney N., James E. Herndon, Annie Lloyd, Henry S. Friedman, Darell D. Bigner, Sandra H. Bigner, and Roger E. McLendon. “Comparative genomic hybridization analysis of astrocytomas: prognostic and diagnostic implications.” J Mol Diagn 6, no. 3 (August 2004): 166–79. https://doi.org/10.1016/S1525-1578(10)60507-7.
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  - McLendon, Roger E., Ahmed Rasheed, Rodney Wiltshire, and James Herndon. “Correlation of 1p-19q-defects in human gliomas with the light microscopic appearance of oligodendroglioma.” Mod Pathol 17, no. 5 (May 2004): 604–5. https://doi.org/10.1038/modpathol.3800077.
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  - Rich, Jeremy N., David A. Reardon, Terry Peery, Jeannette M. Dowell, Jennifer A. Quinn, Kara L. Penne, Carol J. Wikstrand, et al. “Phase II trial of gefitinib in recurrent glioblastoma.” J Clin Oncol 22, no. 1 (January 1, 2004): 133–42. https://doi.org/10.1200/JCO.2004.08.110.
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  - Alexander, R. T., R. E. McLendon, and T. J. Cummings. “Meningioma with eosinophilic granular inclusions.” Clin Neuropathol 23, no. 6 (2004): 292–97.
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  - Cummings, T. J., T. M. George, H. E. Fuchs, and R. E. McLendon. “The pathology of extracranial scalp and skull masses in young children.” Clin Neuropathol 23, no. 1 (2004): 34–43.
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  - Scheuner, Donalyn, Matthias Gromeier, Monique V. Davies, Andrew J. Dorner, Benbo Song, Rupali V. Patel, Eckard J. Wimmer, Roger E. McLendon, and Randal J. Kaufman. “The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.” Virology 317, no. 2 (December 20, 2003): 263–74. https://doi.org/10.1016/j.virol.2003.08.010.
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  - Grossi, Peter M., Hidenobu Ochiai, Gary E. Archer, Roger E. McLendon, Michael R. Zalutsky, Allan H. Friedman, Henry S. Friedman, Darell D. Bigner, and John H. Sampson. “Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer.” Clin Cancer Res 9, no. 15 (November 15, 2003): 5514–20.
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  - McLendon, Roger E., and Edward C. Halperin. “Is the long-term survival of patients with intracranial glioblastoma multiforme overstated?” Cancer 98, no. 8 (October 15, 2003): 1745–48. https://doi.org/10.1002/cncr.11666.
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  - Sampson, John H., Gamal Akabani, Gary E. Archer, Darell D. Bigner, Mitchel S. Berger, Allan H. Friedman, Henry S. Friedman, et al. “Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors.” J Neurooncol 65, no. 1 (October 2003): 27–35. https://doi.org/10.1023/a:1026290315809.
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  - Gururangan, Sridharan, Colleen McLaughlin, Jennifer Quinn, Jeremy Rich, David Reardon, Edward C. Halperin, James Herndon, et al. “High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas.” J Clin Oncol 21, no. 11 (June 1, 2003): 2187–91. https://doi.org/10.1200/JCO.2003.10.096.
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  - George, David H., Bernd W. Scheithauer, Fügen V. Aker, Paul J. Kurtin, Peter C. Burger, José Cameselle-Teijeiro, Roger E. McLendon, et al. “Primary anaplastic large cell lymphoma of the central nervous system: prognostic effect of ALK-1 expression.” Am J Surg Pathol 27, no. 4 (April 2003): 487–93. https://doi.org/10.1097/00000478-200304000-00008.
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  - Quinn, Jennifer A., David A. Reardon, Allan H. Friedman, Jeremy N. Rich, John H. Sampson, James M. Provenzale, Roger E. McLendon, et al. “Phase II trial of temozolomide in patients with progressive low-grade glioma.” J Clin Oncol 21, no. 4 (February 15, 2003): 646–51. https://doi.org/10.1200/JCO.2003.01.009.
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  - Akabani, Gamal, Roger E. McLendon, Darrell D. Bigner, and Michael R. Zalutsky. “Vascular targeted endoradiotherapy of tumors using alpha-particle-emitting compounds: theoretical analysis.” Int J Radiat Oncol Biol Phys 54, no. 4 (November 15, 2002): 1259–75. https://doi.org/10.1016/s0360-3016(02)03794-x.
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  - Heimberger, Amy B., Chris A. Learn, Gary E. Archer, Roger E. McLendon, Tracy A. Chewning, Frank L. Tuck, John B. Pracyk, et al. “Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).” Clin Cancer Res 8, no. 11 (November 2002): 3496–3502.
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  - Doolittle, Nancy D., Lauren E. Abrey, Nicolay Ferrari, Walter A. Hall, Edward R. Laws, Roger E. McLendon, Leslie L. Muldoon, et al. “Targeted delivery in primary and metastatic brain tumors: summary report of the seventh annual meeting of the Blood-Brain Barrier Disruption Consortium.” Clin Cancer Res 8, no. 6 (June 2002): 1702–9.
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  - Rasheed, Ahmed, James E. Herndon, Timothy T. Stenzel, Jacqueline G. M. Raetz, Jason Kendelhardt, Henry S. Friedman, Allan H. Friedman, Darell D. Bigner, Sandra H. Bigner, and Roger E. McLendon. “Molecular markers of prognosis in astrocytic tumors.” Cancer 94, no. 10 (May 15, 2002): 2688–97. https://doi.org/10.1002/cncr.10544.
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  - Aldosari, Naji, Sandra H. Bigner, Peter C. Burger, Laurence Becker, James L. Kepner, Henry S. Friedman, and Roger E. McLendon. “MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group.” Arch Pathol Lab Med 126, no. 5 (May 2002): 540–44. https://doi.org/10.5858/2002-126-0540-MAMOAI.
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  - Cummings, T. J., R. N. Wiltshire, R. E. McLendon, and A. B. Heimberger. “Comparative genomic hybridization of a biphasic malignant meningioma.” Journal of Neuropathology and Experimental Neurology 61, no. 5 (May 1, 2002): 480–480.
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  - Quinn, Jennifer A., James Pluda, M Eileen Dolan, Shannon Delaney, Richard Kaplan, Jeremy N. Rich, Allan H. Friedman, et al. “Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma.” J Clin Oncol 20, no. 9 (May 1, 2002): 2277–83. https://doi.org/10.1200/JCO.2002.09.084.
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  - Aldosari, Naji, Rodney N. Wiltshire, Amalia Dutra, Evelin Schrock, Roger E. McLendon, Henry S. Friedman, Darell D. Bigner, and Sandra H. Bigner. “Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft.” Neuro Oncol 4, no. 2 (April 2002): 75–85. https://doi.org/10.1093/neuonc/4.2.75.
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  - Turner, Christopher D., Sridharan Gururangan, James Eastwood, Krystal Bottom, Melody Watral, Rodney Beason, Roger E. McLendon, et al. “Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.” Neuro Oncol 4, no. 2 (April 2002): 102–8. https://doi.org/10.1093/neuonc/4.2.109.
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  - Reardon, David A., Gamal Akabani, R Edward Coleman, Allan H. Friedman, Henry S. Friedman, James E. Herndon, Ilkcan Cokgor, et al. “Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas.” J Clin Oncol 20, no. 5 (March 1, 2002): 1389–97. https://doi.org/10.1200/JCO.2002.20.5.1389.
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  - George, D. H., B. W. Scheithauer, F. V. Aker, P. C. Kurtin, P. C. Burger, R. E. McLendon, J. E. Parisi, et al. “Primary anaplastic large cell lymphoma of the central nervous system: ALK-1 and other prognostic factors.” Modern Pathology 15, no. 1 (January 1, 2002): 299A-300A.
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  - George, D. H., B. W. Scheithauer, F. V. Aker, P. C. Kurtin, P. C. Burger, R. E. McLendon, J. E. Parisi, et al. “Primary anaplastic large cell lymphoma of the central nervous system: ALK-1 and other prognostic factors.” Laboratory Investigation 82, no. 1 (January 1, 2002): 299A-300A.
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  - Heimberger, A. B., R. N. Wiltshire, R. Bronec, R. E. McLendon, and T. J. Cummings. “Biphasic malignant meningioma: a comparative genomic hybridization study.” Clin Neuropathol 21, no. 6 (2002): 258–64.
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  - Heimberger, Amy B., Gary E. Archer, Laura E. Crotty, Roger E. McLendon, Allan H. Friedman, Henry S. Friedman, Darell D. Bigner, and John H. Sampson. “Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma.” Neurosurgery 50, no. 1 (January 2002): 158–64. https://doi.org/10.1097/00006123-200201000-00024.
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  - McLendon, Roger E., and James Provenzale. “Glioneuronal tumors of the central nervous system.” Brain Tumor Pathol 19, no. 2 (2002): 51–58. https://doi.org/10.1007/BF02478927.
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  - Eastwood, J. D., D. A. Turner, R. E. McLendon, and J. M. Provenzale. “Diffusion-weighted MR imaging in a patient with spinal meningioma.” Ajr Am J Roentgenol 177, no. 6 (December 2001): 1479–81. https://doi.org/10.2214/ajr.177.6.1771479.
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  - Morgan, M. A., D. S. Enterline, T. Fukushima, R. E. McLendon, and T. J. Cummings. “Endodermal cyst of the oculomotor nerve.” Neuroradiology 43, no. 12 (December 2001): 1063–66. https://doi.org/10.1007/s002340100638.
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  - Cummings, T. J., J. L. Burchette, and R. E. McLendon. “CD34 and dural fibroblasts: the relationship to solitary fibrous tumor and meningioma.” Acta Neuropathol 102, no. 4 (October 2001): 349–54. https://doi.org/10.1007/s004010100389.
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  - Gururangan, S., L. Cokgor, J. N. Rich, S. Edwards, M. L. Affronti, J. A. Quinn, J. E. Herndon, et al. “Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.” Neuro Oncol 3, no. 4 (October 2001): 246–50. https://doi.org/10.1093/neuonc/3.4.246.
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  - Cummings, T. J., R. H. Ebert, J. Provenzale, and R. E. McLendon. “March 2000: A 16 year old female with a cerebellar mass.” Brain Pathol 11, no. 3 (July 2001): 391–93.
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  - Cummings, T. J., C. M. Hulette, S. H. Bigner, G. J. Riggins, and R. E. McLendon. “Ham56-immunoreactive macrophages in untreated infiltrating gliomas.” Arch Pathol Lab Med 125, no. 5 (May 2001): 637–41. https://doi.org/10.5858/2001-125-0637-HIMIUI.
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  - McLendon, R. E., A. Rasheed, R. Wiltshire, J. Herndon, H. Friedman, A. Friedman, D. Bigner, and S. Bigner. “Molecular profiling of astrocytomas.” Journal of Neuropathology and Experimental Neurology 60, no. 5 (May 1, 2001): 535–535.
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  - Wiltshire, R. N., A. Lloyd, J. Powers, J. Kepner, H. Friedman, S. Bigner, and R. E. McLendon. “Comparative genomic hybridization analysis of primitive neuroectodermal tumors.” Journal of Neuropathology and Experimental Neurology 60, no. 5 (May 1, 2001): 541–541.
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  - Zalutsky, M. R., G. Akabani, H. S. Friedman, I. Cokgor, R. E. Coleman, A. H. Friedman, R. E. McLendon, X. G. Zhao, K. L. Alston, and D. D. Bigner. “Radioimmunotherapy of recurrent glioma patients using alpha-particle emitting astatine-211 labeled chimeric anti-tenascin monoclonal antibody.” Journal of Nuclear Medicine 42, no. 5 (May 1, 2001): 121P-122P.
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  - Rich, J. N., C. Guo, R. E. McLendon, D. D. Bigner, X. F. Wang, and C. M. Counter. “A genetically tractable model of human glioma formation.” Cancer Res 61, no. 9 (May 1, 2001): 3556–60.
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  - Winkelstein, B. A., R. E. McLendon, A. Barbir, and B. S. Myers. “An anatomical investigation of the human cervical facet capsule, quantifying muscle insertion area.” J Anat 198, no. Pt 4 (April 2001): 455–61. https://doi.org/10.1046/j.1469-7580.2001.19840455.x.
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  - Cummings, T. J., R. C. Bentley, and R. E. McLendon. “Pathologic quiz case: pituitary mass in a 48-year-old woman.” Arch Pathol Lab Med 125, no. 2 (February 2001): 299–300. https://doi.org/10.5858/2001-125-0299-PQCPMI.
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  - Winkelstein, B. A., R. E. McLendon, A. N. A. Barbir, and B. S. Myers. “An anatomical investigation of the human cervical facet capsule, quantifying muscle insertion area.” Journal of Anatomy 198, no. 4 (2001): 455–61. https://doi.org/10.1017/S0021878201007518.
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  - Cummings, T. J., R. C. Bentley, and R. E. McLendon. “Pathologic quiz case - Pituitary mass in a 48-year-old woman - Pathologic diagnosis: Granular cell tumor of the infundibulum.” Archives of Pathology & Laboratory Medicine 125, no. 2 (2001): 299–300.
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  - Cokgor, I., G. Akabani, C. T. Kuan, H. S. Friedman, A. H. Friedman, R. E. Coleman, R. E. McLendon, et al. “Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas.” J Clin Oncol 18, no. 22 (November 15, 2000): 3862–72. https://doi.org/10.1200/JCO.2000.18.22.3862.
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  - Heimberger, A. B., G. E. Archer, R. E. McLendon, D. Price, A. H. Friedman, H. S. Friedman, D. D. Bigner, and J. H. Sampson. “Oral administration of the specific EGFR tyrosine kinase inhibitor, ZD1839 (Iressa (TM)), is active against EGFR-overexpressing intracranial tumors.” Clinical Cancer Research 6 (November 1, 2000): 4542S-4543S.
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  - Friedman, H. S., J. Pluda, J. A. Quinn, R. B. Ewesuedo, L. Long, A. H. Friedman, I. Cokgor, et al. “Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.” J Clin Oncol 18, no. 20 (October 15, 2000): 3522–28. https://doi.org/10.1200/JCO.2000.18.20.3522.
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  - Heimberger, A. B., G. E. Archer, R. E. McLendon, C. Hulette, A. H. Friedman, H. S. Friedman, D. D. Bigner, and J. H. Sampson. “Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.” Clin Cancer Res 6, no. 10 (October 2000): 4148–53.
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  - McLendon, R. E., C. J. Wikstrand, M. R. Matthews, R. Al-Baradei, S. H. Bigner, and D. D. Bigner. “Glioma-associated antigen expression in oligodendroglial neoplasms. Tenascin and epidermal growth factor receptor.” J Histochem Cytochem 48, no. 8 (August 2000): 1103–10. https://doi.org/10.1177/002215540004800807.
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  - Cummings, T. J., J. Z. Gong, A. H. Friedman, and R. E. McLendon. “Castleman's disease confined to the leptomeninges.” Ann Clin Lab Sci 30, no. 3 (July 2000): 278–82.
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  - Cummings, T. J., R. E. McLendon, and A. Spallone. “Pineal epidermoid cysts [9] (multiple letters).” Journal of Neurosurgery 92, no. 5 (May 17, 2000): 909–10.
  - Akabani, G., R. E. McLendon, D. D. Bigner, and M. R. Zalutsky. “Microdosimetry of alpha-particle-emitting At-211-labelled monoclonal antibody (MAb) using histological images of malignant brain tumors.” Journal of Nuclear Medicine 41, no. 5 (May 1, 2000): 84P-84P.
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  - Cummings, T. J., C. M. Hulette, S. Bigner, A. Lal, G. J. Riggins, J. L. Burchette, and R. E. McLendon. “HAM56 immunoreactivity in infiltrating glial neoplasms.” Journal of Neuropathology and Experimental Neurology 59, no. 5 (May 1, 2000): 437–437.
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  - Cummings, T. J., and R. E. McLendon. “Pineal epidermoid cysts.” J Neurosurg 92, no. 5 (May 2000): 909–10. https://doi.org/10.3171/jns.2000.92.5.0909.
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  - Cummings, T. J., J. M. Provenzale, S. B. Hunter, A. H. Friedman, G. K. Klintworth, S. H. Bigner, and R. E. McLendon. “Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis.” Acta Neuropathol 99, no. 5 (May 2000): 563–70. https://doi.org/10.1007/s004010051161.
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  - Aldosari, N., B. K. Rasheed, R. E. McLendon, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “Characterization of chromosome 17 abnormalities in medulloblastomas.” Acta Neuropathol 99, no. 4 (April 2000): 345–51. https://doi.org/10.1007/s004010051134.
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  - Provenzale, J. M., U. Ali, D. P. Barboriak, D. F. Kallmes, D. M. Delong, and R. E. McLendon. “Comparison of patient age with MR imaging features of gangliogliomas.” Ajr Am J Roentgenol 174, no. 3 (March 2000): 859–62. https://doi.org/10.2214/ajr.174.3.1740859.
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  - Akabani, G., I. Cokgor, R. E. Coleman, D. González Trotter, T. Z. Wong, H. S. Friedman, A. H. Friedman, et al. “Dosimetry and dose-response relationships in newly diagnosed patients with malignant gliomas treated with iodine-131-labeled anti-tenascin monoclonal antibody 81C6 therapy.” Int J Radiat Oncol Biol Phys 46, no. 4 (March 1, 2000): 947–58. https://doi.org/10.1016/s0360-3016(99)00500-3.
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  - Cummings, T. J., J. F. Madden, L. Gray, A. H. Friedman, and R. E. McLendon. “Parasitic lesion of the insula suggesting cerebral sparganosis: case report.” Neuroradiology 42, no. 3 (March 2000): 206–8. https://doi.org/10.1007/s002340050047.
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  - Heimberger, A. B., L. E. Crotty, G. E. Archer, R. E. McLendon, A. Friedman, G. Dranoff, D. D. Bigner, and J. H. Sampson. “Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma.” J Neuroimmunol 103, no. 1 (February 1, 2000): 16–25. https://doi.org/10.1016/s0165-5728(99)00172-1.
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  - Cummings, T. J., R. E. McLendon, A. T. Villavicencio, A. H. Friedman, J. L. Burchette, and R. C. Bentley. “Human chorionic gonadotropin beta subunit protein immunoreactivity in pituitary adenomas: Pathologic features.” Brain Pathology 10, no. 4 (2000): 746–47.
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  - Nuckols, J. D., K. Liu, J. L. Burchette, R. E. McLendon, and S. T. Traweek. “Primary central nervous system lymphomas: a 30-year experience at a single institution.” Mod Pathol 12, no. 12 (December 1999): 1167–73.
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  - Lal, A., A. E. Lash, S. F. Altschul, V. Velculescu, L. Zhang, R. E. McLendon, M. A. Marra, et al. “A public database for gene expression in human cancers.” Cancer Res 59, no. 21 (November 1, 1999): 5403–7.
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  - Chu, C. T., D. N. Howell, J. C. Morgenlander, C. M. Hulette, R. E. McLendon, and S. E. Miller. “Electron microscopic diagnosis of human flavivirus encephalitis: use of confocal microscopy as an aid.” Am J Surg Pathol 23, no. 10 (October 1999): 1217–26. https://doi.org/10.1097/00000478-199910000-00006.
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  - Archer, G. E., J. H. Sampson, I. A. Lorimer, R. E. McLendon, C. T. Kuan, A. H. Friedman, H. S. Friedman, I. H. Pastan, and D. D. Bigner. “Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.” Clin Cancer Res 5, no. 9 (September 1999): 2646–52.
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  - Zalutsky, M. R., G. Akabani, I. Cokgor, H. S. Friedman, R. E. Coleman, A. H. Friedman, R. E. McLendon, and D. D. Bigner. “Astatine-211 labeled chimeric anti-tenascin antibody: Phase I trial in brain tumor resection cavity patients.” European Journal of Nuclear Medicine 26, no. 9 (September 1, 1999): 1215–1215.
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  - McLendon, R. E., G. E. Archer, R. H. Larsen, G. Akabani, D. D. Bigner, and M. R. Zalutsky. “Radiotoxicity of systemically administered 211At-labeled human/mouse chimeric monoclonal antibody: a long-term survival study with histologic analysis.” Int J Radiat Oncol Biol Phys 45, no. 2 (September 1, 1999): 491–99. https://doi.org/10.1016/s0360-3016(99)00206-0.
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  - Bigner, S. H., M. R. Matthews, B. K. Rasheed, R. N. Wiltshire, H. S. Friedman, A. H. Friedman, T. T. Stenzel, D. M. Dawes, R. E. McLendon, and D. D. Bigner. “Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization.” Am J Pathol 155, no. 2 (August 1999): 375–86. https://doi.org/10.1016/S0002-9440(10)65134-6.
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  - Sampson, J. H., G. E. Archer, A. T. Villavicencio, R. E. McLendon, A. H. Friedman, W. R. Bishop, D. D. Bigner, and H. S. Friedman. “Treatment of neoplastic meningitis with intrathecal temozolomide.” Clin Cancer Res 5, no. 5 (May 1999): 1183–88.
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  - Cummings, T. J., C. T. Chu, and R. E. McLendon. “LONG TERM RECURRENT JUVENILE PILOCYTIC ASTROCYTOMAS OF THE CEREBELLUM.” Journal of Neuropathology and Experimental Neurology 58, no. 5 (May 1999): 538–538. https://doi.org/10.1097/00005072-199905000-00126.
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  - Dodd, L. G., E. M. Marom, R. C. Dash, M. R. Matthews, and R. E. McLendon. “Fine-needle aspiration cytology of "ancient" schwannoma.” Diagn Cytopathol 20, no. 5 (May 1999): 307–11. https://doi.org/10.1002/(sici)1097-0339(199905)20:5<307::aid-dc12>3.0.co;2-f.
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  - Friedman, H. S., W. P. Petros, A. H. Friedman, L. J. Schaaf, T. Kerby, J. Lawyer, M. Parry, et al. “Irinotecan therapy in adults with recurrent or progressive malignant glioma.” J Clin Oncol 17, no. 5 (May 1999): 1516–25. https://doi.org/10.1200/JCO.1999.17.5.1516.
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  - Dash, R. C., J. M. Provenzale, R. D. McComb, D. A. Perry, D. C. Longee, and R. E. McLendon. “Malignant supratentorial ganglioglioma (ganglion cell-giant cell glioblastoma): a case report and review of the literature.” Arch Pathol Lab Med 123, no. 4 (April 1999): 342–45. https://doi.org/10.5858/1999-123-0342-MSGGCG.
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  - Provenzale, J. M., M. A. Arata, T. G. Turkington, R. E. McLendon, and R. E. Coleman. “Gangliogliomas: characterization by registered positron emission tomography-MR images.” Ajr Am J Roentgenol 172, no. 4 (April 1999): 1103–7. https://doi.org/10.2214/ajr.172.4.10587156.
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  - Friedman, H. S., T. Kerby, S. Fields, J. E. Zilisch, D. Graden, R. E. McLendon, P. J. Houghton, S. Arbuck, I. Cokgor, and A. H. Friedman. “Topotecan treatment of adults with primary malignant glioma. The Brain Tumor Center at Duke.” Cancer 85, no. 5 (March 1, 1999): 1160–65.
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  - McLendon, R. E., H. S. Friedman, H. E. Fuchs, L. E. Kun, and S. H. Bigner. “Diagnostic markers in paediatric medulloblastoma: a Paediatric Oncology Group Study.” Histopathology 34, no. 2 (February 1999): 154–62. https://doi.org/10.1046/j.1365-2559.1999.00577.x.
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  - Cummings, T. J., J. Provenzale, S. Hunter, H. S. Friedman, G. Klintworth, S. H. Bigner, and R. E. McLendon. “Gliomas of the optic nerve in children and adults.” Laboratory Investigation 79, no. 1 (January 1, 1999): 170A-170A.
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  - Archer, G. E., J. H. Sampson, R. E. McLendon, A. H. Friedman, O. M. Colvin, M. Rose, H. Sands, et al. “Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.” J Neurooncol 44, no. 3 (1999): 233–41. https://doi.org/10.1023/a:1006304424346.
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  - Bigner, S. H., B. K. Rasheed, R. Wiltshire, and R. E. McLendon. “Morphologic and molecular genetic aspects of oligodendroglial neoplasms.” Neuro Oncol 1, no. 1 (January 1999): 52–60. https://doi.org/10.1093/neuonc/1.1.52.
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  - Cummings, T. J., C. M. Hulette, D. C. Longee, K. S. Bottom, R. E. McLendon, and C. T. Chu. “Gliomatosis cerebri: cytologic and autopsy findings in a case involving the entire neuraxis.” Clin Neuropathol 18, no. 4 (1999): 190–97.
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  - Cummings, T. J., R. C. Bentley, L. Gray, W. E. Check, T. E. Lanier, and R. E. McLendon. “Meningioma of the fourth ventricle.” Clin Neuropathol 18, no. 5 (1999): 265–69.
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  - Marriott, C. J. C., W. Thorstad, G. Akabani, M. T. Brown, R. E. McLendon, M. W. Hanson, and R. Edward Coleman. “Locally increased uptake of fluorine-18fluorodeoxyglucose after intracavitary administration of iodine-131-labeled antibody for primary brain tumors.” Journal of Nuclear Medicine 39, no. 8 SUPPL. (December 1, 1998): 1376–80.
  - Friedman, H. S., R. E. McLendon, T. Kerby, M. Dugan, S. H. Bigner, A. J. Henry, D. M. Ashley, et al. “DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.” J Clin Oncol 16, no. 12 (December 1998): 3851–57. https://doi.org/10.1200/JCO.1998.16.12.3851.
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  - Koen, J. L., R. E. McLendon, and T. M. George. “Intradural spinal teratoma: evidence for a dysembryogenic origin. Report of four cases.” J Neurosurg 89, no. 5 (November 1998): 844–51. https://doi.org/10.3171/jns.1998.89.5.0844.
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  - Friedman, H. S., D. M. Kokkinakis, J. Pluda, A. H. Friedman, I. Cokgor, M. M. Haglund, D. M. Ashley, et al. “Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma.” J Clin Oncol 16, no. 11 (November 1998): 3570–75. https://doi.org/10.1200/JCO.1998.16.11.3570.
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  - Komori, T., B. W. Scheithauer, D. C. Anthony, M. K. Rosenblum, R. E. McLendon, R. M. Scott, H. Okazaki, and M. Kobayashi. “Papillary glioneuronal tumor: a new variant of mixed neuronal-glial neoplasm.” Am J Surg Pathol 22, no. 10 (October 1998): 1171–83. https://doi.org/10.1097/00000478-199810000-00002.
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  - Ritter, A. M., K. R. Hess, R. E. McLendon, and L. A. Langford. “Ependymomas: MIB-1 proliferation index and survival.” J Neurooncol 40, no. 1 (October 1998): 51–57. https://doi.org/10.1023/a:1006082622699.
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  - Marriott, C. J., W. Thorstad, G. Akabani, M. T. Brown, R. E. McLendon, M. W. Hanson, and R. E. Coleman. “Locally increased uptake of fluorine-18-fluorodeoxyglucose after intracavitary administration of iodine-131-labeled antibody for primary brain tumors.” J Nucl Med 39, no. 8 (August 1998): 1376–80.
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  - Lee, S. E., S. P. Johnson, L. P. Hale, J. Li, N. Bullock, H. Fuchs, A. Friedman, et al. “Analysis of DNA mismatch repair proteins in human medulloblastoma.” Clin Cancer Res 4, no. 6 (June 1998): 1415–19.
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  - Bigner, D. D., M. T. Brown, A. H. Friedman, R. E. Coleman, G. Akabani, H. S. Friedman, W. L. Thorstad, et al. “Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results.” J Clin Oncol 16, no. 6 (June 1998): 2202–12. https://doi.org/10.1200/JCO.1998.16.6.2202.
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  - Matthews, M. R., B. K. A. Rasheed, R. E. McLendon, C. J. Wikstrand, D. D. Bigner, and S. H. Bigner. “Molecular and immunohistologic (IHC) studies on oligodendroglial (O) tumors.” Journal of Neuropathology and Experimental Neurology 57, no. 5 (May 1, 1998): 473–473.
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  - McLendon, R. E., L. Cleveland, C. Pegram, S. H. Bigner, D. D. Bigner, and H. S. Friedman. “Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.” Lab Invest 78, no. 5 (May 1998): 643–44.
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  - Chu, C. T., D. N. Howell, J. C. Morgenlander, R. E. McLendon, and S. E. Miller. “ELECTRON MICROSCOPIC DIAGNOSIS OF ARBOVIRAL MENINOOENCEPHALITIS.” Journal of Neuropathology and Experimental Neurology 57, no. 5 (May 1998): 505–505. https://doi.org/10.1097/00005072-199805000-00161.
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  - Moghrabi, A., H. S. Friedman, D. M. Ashley, K. S. Bottom, T. Kerby, E. Stewart, C. Bruggers, et al. “Phase II study of carboplatin (CBDCA) in progressive low-grade gliomas.” Neurosurg Focus 4, no. 4 (April 15, 1998): e3. https://doi.org/10.3171/foc.1998.4.4.6.
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  - McCowage, G. B., H. S. Friedman, A. Moghrabi, T. Kerby, L. Ferrell, E. Stewart, M. Duncan-Brown, et al. “Activity of high-dose cyclophosphamide in the treatment of childhood malignant gliomas.” Med Pediatr Oncol 30, no. 2 (February 1998): 75–80. https://doi.org/10.1002/(sici)1096-911x(199802)30:2<75::aid-mpo1>3.0.co;2-x.
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  - McLendon, R. E., H. S. Friedman, S. H. Bigner, and P. L. Modrich. “DNA mismatch repair enzyme detection in adult glioblastoma (GBM) by immunohistochemistry.” Modern Pathology 11, no. 1 (January 1, 1998): 160A-160A.
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  - Slavik, T., R. C. Bentley, L. Gray, H. E. Fuchs, and R. E. McLendon. “Solitary fibrous tumor of the meninges occurring after irradiation of a mixed germ cell tumor of the pineal gland.” Clin Neuropathol 17, no. 1 (1998): 55–60.
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  - Stenzel, T. T., B. K. A. Rasheed, R. E. McLendon, R. Parsons, A. H. Friedman, H. S. Friedman, and S. H. Bigner. “Pten gene mutations are seen in high grade, but not in low grade gliomas.” Clinical Chemistry 43, no. 11 (November 1, 1997): 25–25.
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  - Rasheed, B. K., T. T. Stenzel, R. E. McLendon, R. Parsons, A. H. Friedman, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “PTEN gene mutations are seen in high-grade but not in low-grade gliomas.” Cancer Res 57, no. 19 (October 1, 1997): 4187–90.
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  - Wikstrand, C. J., R. E. McLendon, A. H. Friedman, and D. D. Bigner. “Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIII.” Cancer Res 57, no. 18 (September 15, 1997): 4130–40.
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  - Bigner, S. H., R. E. McLendon, H. Fuchs, P. E. McKeever, and H. S. Friedman. “Chromosomal characteristics of childhood brain tumors.” Cancer Genet Cytogenet 97, no. 2 (September 1997): 125–34. https://doi.org/10.1016/s0165-4608(96)00404-9.
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  - Komori, T., B. W. Scheithauer, D. C. Anthony, M. K. Rosenblum, and R. E. McLendon. “Pseudopapillary glioneuronal tumor (PGNT).” Brain Pathology 7, no. 4 (September 1, 1997): 1189–1189.
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  - McLendon, R. E., R. C. Bentley, J. E. Parisi, R. D. Tien, J. C. Harrison, N. J. Tarbell, A. L. Billitt, R. J. Gualtieri, and H. S. Friedman. “Malignant supratentorial glial-neuronal neoplasms: report of two cases and review of the literature.” Arch Pathol Lab Med 121, no. 5 (May 1997): 485–92.
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  - Ashraf, R., R. C. Bentley, A. N. Awan, R. E. McLendon, and M. W. Ragozzino. “Implantation metastasis of primary malignant rhabdoid tumor of the brain in an adult (one case report).” Med Pediatr Oncol 28, no. 3 (March 1997): 223–27. https://doi.org/10.1002/(sici)1096-911x(199703)28:3<223::aid-mpo14>3.0.co;2-f.
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  - Moghrabi, A., R. Tien, H. Fuchs, D. Longee, R. McLendon, and H. S. Friedman. “False positive images in the follow-up of patients with brain tumors.” Med Pediatr Oncol 28, no. 2 (February 1997): 127–31. https://doi.org/10.1002/(sici)1096-911x(199702)28:2<127::aid-mpo6>3.0.co;2-m.
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  - Provenzale, J. M., P. Schaefer, S. T. Traweek, J. Ferry, J. O. Moore, A. H. Friedman, and R. E. McLendon. “Craniocerebral plasmacytoma: MR features.” Ajnr Am J Neuroradiol 18, no. 2 (February 1997): 389–92.
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  - Bean, J. M., G. E. Archer, M. T. Munley, E. Ong, S. A. Snyder, Z. A. Haroon, R. E. McLendon, et al. “2013 The impact of hypoxia and oxygenation modification on the radiation response of an intracranial rat glioma.” International Journal of Radiation Oncology*Biology*Physics 39, no. 2 (January 1997): 247–247. https://doi.org/10.1016/s0360-3016(97)80782-1.
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  - Kurpad, S. N., M. E. Dolan, R. E. McLendon, G. E. Archer, R. C. Moschel, A. E. Pegg, D. D. Bigner, and H. S. Friedman. “Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea.” Cancer Chemother Pharmacol 39, no. 4 (1997): 307–16. https://doi.org/10.1007/s002800050577.
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  - Felsberg, G. J., J. P. Glass, R. D. Tien, and R. McLendon. “Gliomatosis cerebri presenting with optic nerve involvement: MRI.” Neuroradiology 38, no. 8 (November 1996): 774–77. https://doi.org/10.1007/s002340050345.
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  - McCowage, G., R. Tien, R. McLendon, G. Felsberg, H. Fuchs, M. L. Graham, J. Kurtzberg, et al. “Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.” Med Pediatr Oncol 27, no. 1 (July 1996): 32–39. https://doi.org/10.1002/(SICI)1096-911X(199607)27:1<32::AID-MPO7>3.0.CO;2-V.
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  - Ashley, D. M., D. Longee, R. Tien, H. Fuchs, M. L. Graham, J. Kurtzberg, J. Casey, et al. “Treatment of patients with pineoblastoma with high dose cyclophosphamide.” Med Pediatr Oncol 26, no. 6 (June 1996): 387–92. https://doi.org/10.1002/(SICI)1096-911X(199606)26:6<387::AID-MPO3>3.0.CO;2-D.
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  - Brown, M. T., R. E. Coleman, A. H. Friedman, H. S. Friedman, R. E. McLendon, R. Reiman, G. J. Felsberg, et al. “Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.” Clin Cancer Res 2, no. 6 (June 1996): 963–72.
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  - McLendon, R. E., A. H. Friedman, J. M. Provenzale, M. T. Brown, and K. P. Mann. “Castleman's disease (plasma cell variant) confined to the leptomeninges.” Journal of Neuropathology and Experimental Neurology 55, no. 5 (May 1, 1996): 76–76.
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  - McLendon, R. E., K. M. Fung, R. C. Bentley, B. K. Ahmed Rasheed, J. Q. Trojanowski, S. H. Bigner, D. D. Bigner, and H. S. Friedman. “Production and characterization of two ependymoma xenografts.” J Neuropathol Exp Neurol 55, no. 5 (May 1996): 540–48. https://doi.org/10.1097/00005072-199605000-00007.
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  - Towfighi, J., M. M. Salam, R. E. McLendon, S. Powers, and R. B. Page. “Ganglion cell-containing tumors of the pituitary gland.” Arch Pathol Lab Med 120, no. 4 (April 1996): 369–77.
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  - McLendon, R. E., G. E. Archer, P. K. Garg, D. D. Bigner, and M. R. Zalutsky. “Radiotoxicity of systematically administered [211At]astatide in B6C3F1 and BALB/c (nu/nu) mice: a long-term survival study with histologic analysis.” Int J Radiat Oncol Biol Phys 35, no. 1 (April 1, 1996): 69–80. https://doi.org/10.1016/s0360-3016(96)85013-9.
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  - Provenzale, J. M., and R. E. McLendon. “Spinal angiolipomas: MR features.” Ajnr Am J Neuroradiol 17, no. 4 (April 1996): 713–19.
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  - Blaeker, H., B. K. Rasheed, R. E. McLendon, H. S. Friedman, S. K. Batra, H. E. Fuchs, and S. H. Bigner. “Microsatellite analysis of childhood brain tumors.” Genes Chromosomes Cancer 15, no. 1 (January 1996): 54–63. https://doi.org/10.1002/(SICI)1098-2264(199601)15:1<54::AID-GCC8>3.0.CO;2-3.
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  - Bigner, D. D., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, L. H. Pai, J. E. Herndon, and I. H. Pastan. “Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.” Clin Cancer Res 1, no. 12 (December 1995): 1545–55.
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  - Lirng, J. F., D. S. Enterline, R. D. Tien, H. Fuchs, H. S. Friedman, K. S. Ellington, and R. P. McLendon. “MRI of papillary meningiomas in children.” Pediatr Radiol 25 Suppl 1 (November 1995): S9-13.
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  - Kurpad, S. N., X. G. Zhao, C. J. Wikstrand, S. K. Batra, R. E. McLendon, and D. D. Bigner. “Tumor antigens in astrocytic gliomas.” Glia 15, no. 3 (November 1995): 244–56. https://doi.org/10.1002/glia.440150306.
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  - Kurpad, S. N., H. S. Friedman, G. E. Archer, R. E. McLendon, W. M. Petros, H. E. Fuchs, A. Guaspari, and D. D. Bigner. “Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats.” Cancer Res 55, no. 17 (September 1, 1995): 3803–9.
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  - Felsberg, G. J., R. D. Tien, and R. E. McLendon. “Frontoethmoidal giant cell reparative granuloma.” Ajnr Am J Neuroradiol 16, no. 7 (August 1995): 1551–54.
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  - Wikstrand, C. J., L. P. Hale, S. K. Batra, M. L. Hill, P. A. Humphrey, S. N. Kurpad, R. E. McLendon, D. Moscatello, C. N. Pegram, and C. J. Reist. “Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas.” Cancer Res 55, no. 14 (July 15, 1995): 3140–48.
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  - Lirng, J. F., R. D. Tien, A. K. Osumi, J. F. Madden, R. P. McLendon, and D. Sexton. “Cerebral phaeohyphomycosis complicated with brain abscess: a case report.” Zhonghua Yi Xue Za Zhi (Taipei) 55, no. 6 (June 1995): 491–95.
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  - Foltz, R. M., R. E. McLendon, H. S. Friedman, R. K. Dodge, D. D. Bigner, and M. W. Dewhirst. “A pial window model for the intracranial study of human glioma microvascular function.” Neurosurgery 36, no. 5 (May 1995): 976–84. https://doi.org/10.1227/00006123-199505000-00014.
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  - Kochi, Masato, Roger E. McLendon, and Lauren A. Langford. “MIB-1 (Ki-67 ANTIGEN) LABELING INDICES IN NON-NEOPLASTIC GLIAL CELL PROLIFERATIONS.” Journal of Neuropathology and Experimental Neurology 54, no. 3 (May 1995): 461–461. https://doi.org/10.1097/00005072-199505000-00215.
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  - Hitchcock, M. G., K. S. Ellington, A. H. Friedman, J. M. Provenzaie, and R. E. McLendon. “Shadow cells in an intracranial dermoid cyst.” Arch Pathol Lab Med 119, no. 4 (April 1995): 371–73.
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  - Pastan, I. H., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, Q. C. Wang, L. H. Pai, J. Herndon, and D. D. Bigner. “Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.” Proc Natl Acad Sci U S A 92, no. 7 (March 28, 1995): 2765–69. https://doi.org/10.1073/pnas.92.7.2765.
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  - Hinton, J. L., D. J. Warejcka, Y. Mei, R. E. McLendon, C. Laurencin, P. A. Lucas, and J. S. Robinson. “Inhibition of epidural scar formation after lumbar laminectomy in the rat.” Spine (Phila Pa 1976) 20, no. 5 (March 1, 1995): 564–70. https://doi.org/10.1097/00007632-199503010-00011.
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  - Batra, S. K., R. E. McLendon, J. S. Koo, S. Castelino-Prabhu, H. E. Fuchs, J. P. Krischer, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “Prognostic implications of chromosome 17p deletions in human medulloblastomas.” J Neurooncol 24, no. 1 (1995): 39–45. https://doi.org/10.1007/BF01052657.
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  - Bigner, D. D., M. Brown, R. E. Coleman, A. H. Friedman, H. S. Friedman, R. E. McLendon, S. H. Bigner, X. G. Zhao, C. J. Wikstrand, and C. N. Pegram. “Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2--a preliminary report.” J Neurooncol 24, no. 1 (1995): 109–22. https://doi.org/10.1007/BF01052668.
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  - Provenzale, J. M., A. L. Weber, G. K. Klintworth, and R. E. McLendon. “Radiologic-pathologic correlation. Bilateral retinoblastoma with coexistent pinealoblastoma (trilateral retinoblastoma).” Ajnr Am J Neuroradiol 16, no. 1 (January 1995): 157–65.
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  - Friedman, H. S., G. E. Archer, R. E. McLendon, J. M. Schuster, O. M. Colvin, A. Guaspari, R. Blum, P. A. Savina, H. E. Fuchs, and D. D. Bigner. “Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.” Cancer Res 54, no. 17 (September 1, 1994): 4710–14.
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  - Zalutsky, M. R., R. E. McLendon, P. K. Garg, G. E. Archer, J. M. Schuster, and D. D. Bigner. “Radioimmunotherapy of neoplastic meningitis in rats using an alpha-particle-emitting immunoconjugate.” Cancer Res 54, no. 17 (September 1, 1994): 4719–25.
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  - McLendon, R. E., and D. D. Bigner. “Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations.” Brain Pathol 4, no. 3 (July 1994): 221–28. https://doi.org/10.1111/j.1750-3639.1994.tb00837.x.
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  - Rasheed, B. K., R. E. McLendon, J. E. Herndon, H. S. Friedman, A. H. Friedman, D. D. Bigner, and S. H. Bigner. “Alterations of the TP53 gene in human gliomas.” Cancer Res 54, no. 5 (March 1, 1994): 1324–30.
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  - MCLENDON, R. E., A. BRADLEY, J. E. PARISI, B. W. SCHEITHAUER, G. FELSBERG, and H. S. FRIEDMAN. “COMPOSITE NEUROBLASTOMA MALIGNANT GLIOMA.” Laboratory Investigation 70, no. 1 (January 1, 1994): A139–A139.
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  - Moghrabi, A., H. S. Friedman, R. McLendon, B. Hockenberger, R. D. Tien, E. C. Halperin, and W. J. Oakes. “Arteriovenous malformation mimicking recurrent medulloblastoma.” Med Pediatr Oncol 22, no. 2 (1994): 140–43. https://doi.org/10.1002/mpo.2950220216.
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  - Osumi, A. K., R. E. Mclendon, R. D. Tien, H. S. Friedman, M. Graham, B. Hockenberger, E. C. Halperin, and W. J. Oakes. “Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma.” Clin Neuropathol 13, no. 5 (1994): 281–85.
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  - Wikstrand, C. J., P. Fredman, R. R. McLendon, L. Svennerholm, and D. D. Bigner. “Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro.” Mol Chem Neuropathol 21, no. 2–3 (1994): 129–38. https://doi.org/10.1007/BF02815347.
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  - Schuster, J. M., H. S. Friedman, G. E. Archer, H. E. Fuchs, R. E. McLendon, O. M. Colvin, and D. D. Bigner. “Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide.” Cancer Res 53, no. 10 Suppl (May 15, 1993): 2338–43.
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  - McLENDON, R. E., S. K. BATRA, H. S. FRIEDMAN, B. K. A. RASHEED, D. D. BIGNER, and S. H. BIGNER. “EXPRESSION OF C-MYC IN MEDULLOBLASTOMA XENOGRAFTS.” Journal of Neuropathology and Experimental Neurology 52, no. 3 (May 1993): 267–267. https://doi.org/10.1097/00005072-199305000-00030.
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  - Wikstrand, C. J., D. C. Longee, R. E. McLendon, G. N. Fuller, H. S. Friedman, P. Fredman, L. Svennerholm, and D. D. Bigner. “Lactotetraose series ganglioside 3',6'-isoLD1 in tumors of central nervous and other systems in vitro and in vivo.” Cancer Res 53, no. 1 (January 1, 1993): 120–26.
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  - Schuster, J. M., H. S. Friedman, G. E. Archer, H. E. Fuchs, R. E. McLendon, and D. D. Bigner. “Intraarterial Therapy of Human Glioma Xenografts in Athymic Rats Using 4-Hydroperoxycyclophosphamide.” Cancer Research 53, no. 10 (January 1, 1993): 2338–43.
  - Szpak, C., R. E. McLendon, J. F. Simpson, A. Thor, and W. W. Johnston. “The application of monoclonal antibodies in the cytologic evaluation of tumors.” Clin Lab Med 10, no. 1 (March 1990): 77–103.
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  - McLendon, R. E., W. J. Oakes, E. R. Heinz, A. E. Yeates, and P. C. Burger. “Adipose tissue in the filum terminale: a computed tomographic finding that may indicate tethering of the spinal cord.” Neurosurgery 22, no. 5 (May 1988): 873–76.
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  - Woodruff, W. W., W. T. Djang, R. E. McLendon, E. R. Heinz, and D. R. Voorhees. “Intracerebral malignant melanoma: high-field-strength MR imaging.” Radiology 165, no. 1 (October 1987): 209–13. https://doi.org/10.1148/radiology.165.1.3628773.
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  - McLendon, R. E., P. C. Burger, S. H. Bigner, and D. D. Bigner. “PRIMARY CENTRAL NERVOUS SYSTEM NEOPLASMS IN FISCHER-344 RATS RECEIVING CHRONIC LIFETIME EXPOSURE TO ACRYLONITRILE (ACN).” Journal of Neuropathology and Experimental Neurology 46, no. 3 (May 1987): 389–389. https://doi.org/10.1097/00005072-198705000-00178.
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  - Wikstrand, C. J., R. E. McLendon, S. Carrel, J. T. Kemshead, J. P. Mach, H. B. Coakham, N. de Tribolet, D. E. Bullard, M. R. Zalutsky, and D. D. Bigner. “Comparative localization of glioma-reactive monoclonal antibodies in vivo in an athymic mouse human glioma xenograft model.” J Neuroimmunol 15, no. 1 (May 1987): 37–56. https://doi.org/10.1016/0165-5728(87)90005-1.
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  - Burger, P. C., C. E. Rawlings, E. B. Cox, R. E. McLendon, S. C. Schold, and D. E. Bullard. “Clinicopathologic correlations in the oligodendroglioma.” Cancer 59, no. 7 (April 1, 1987): 1345–52. https://doi.org/10.1002/1097-0142(19870401)59:7<1345::aid-cncr2820590719>3.0.co;2-a.
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  - McLendon, R. E., P. C. Burger, C. N. Pegram, L. F. Eng, and D. D. Bigner. “The immunohistochemical application of three anti-GFAP monoclonal antibodies to formalin-fixed, paraffin-embedded, normal and neoplastic brain tissues.” J Neuropathol Exp Neurol 45, no. 6 (November 1986): 692–703. https://doi.org/10.1097/00005072-198611000-00007.
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  - Wikstrand, C. J., R. E. McLendon, D. E. Bullard, P. Fredman, L. Svennerholm, and D. D. Bigner. “Production and characterization of two human glioma xenograft-localizing monoclonal antibodies.” Cancer Res 46, no. 11 (November 1986): 5933–40.
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  - Woodruff, W. W., A. E. Yeates, and R. E. McLendon. “Perineural tumor extension to the cavernous sinus from superficial facial carcinoma: CT manifestations.” Radiology 161, no. 2 (November 1986): 395–99. https://doi.org/10.1148/radiology.161.2.3763908.
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  - Fulkerson, W. J., R. E. McLendon, and L. R. Prosnitz. “Adult respiratory distress syndrome after limited thoracic radiotherapy.” Cancer 57, no. 10 (May 15, 1986): 1941–46. https://doi.org/10.1002/1097-0142(19860515)57:10<1941::aid-cncr2820571009>3.0.co;2-9.
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  - McLendon, R. E., C. J. Wikstrand, M. A. Bourdon, and D. P. Bigner. “IMMUNOPEROXIDASE HISTOCHEMISTRY (IPH) OF ANTIGLIOMA MONOCLONAL ANTI-BODIES (MABʼS) ON NORMAL AND NEOPLASTIC CENTRAL NERVOUS SYSTEM TISSUES (CNS).” Journal of Neuropathology and Experimental Neurology 45, no. 3 (May 1986): 318–318. https://doi.org/10.1097/00005072-198605000-00016.
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  - TUCKER, J. A., M. R. HOFFMAN, R. E. MCLENDON, P. INGRAM, and J. D. SHELBURNE. “ELECTRON-PROBE MICROANALYSIS OF HALLERVORDEN-SPATZ DISEASE.” American Journal of Clinical Pathology 85, no. 3 (March 1, 1986): 385–385.
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  - MCLENDON, R. E., C. A. SZPAK, W. W. JOHNSTON, A. THOR, and P. C. BURGER. “APPLICATION OF MONOCLONAL-ANTIBODY (MAB) B72.3 IN THE EVALUATION OF TUMORS METASTATIC TO THE CENTRAL-NERVOUS-SYSTEM (CNS).” Laboratory Investigation 54, no. 1 (January 1, 1986): A41–A41.
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  - MCLENDON, R. E., F. S. VOGEL, J. PIATT, and P. C. BURGER. “HYDRANENCEPHALY ASSOCIATED WITH UNILATERAL STENOSIS OF THE INTRASPHENOIDAL SEGMENT OF THE INTERNAL CAROTID-ARTERY.” Laboratory Investigation 54, no. 1 (January 1, 1986): P6–P6.
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  - MCLENDON, R. E., G. A. CAMPBELL, C. E. COFFEY, F. S. VOGEL, and P. C. BURGER. “MULTIPLE INFARCTS AND ALZHEIMERS-DISEASE MIMICKING HUNTINGTONS-DISEASE.” Laboratory Investigation 54, no. 1 (January 1, 1986): A41–A41.
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  - MCLENDON, R. E., J. A. TUCKER, and J. L. BURCHETTE. “SCANNING ELECTRON-MICROSCOPIC AND LIGHT MICROSCOPIC OBSERVATIONS ON TRYPSIN TREATED FORMALIN FIXED TISSUES.” Laboratory Investigation 54, no. 1 (January 1, 1986): A41–A41.
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  - MCLENDON, R. E., P. C. BURGER, C. J. WIKSTRAND, C. N. PEGRAM, L. F. ENG, and D. D. BIGNER. “THE HISTOCHEMICAL-LOCALIZATION OF GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP) IN HUMAN CENTRAL-NERVOUS-SYSTEM (CNS) NEOPLASMS BY MONOCLONAL-ANTIBODIES (MCAS).” Journal of Neuro Oncology 4, no. 1 (January 1, 1986): 96–96.
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  - McLendon, R. E., V. L. Roggli, W. L. Foster, and D. Becsey. “Carcinoma of the lung with osseous stromal metaplasia.” Arch Pathol Lab Med 109, no. 11 (November 1985): 1051–53.
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  - McLendon, R. E., J. S. Robinson, D. B. Chambers, S. Grufferman, and P. C. Burger. “The glioblastoma multiforme in Georgia, 1977-1981.” Cancer 56, no. 4 (August 15, 1985): 894–97. https://doi.org/10.1002/1097-0142(19850815)56:4<894::aid-cncr2820560432>3.0.co;2-#.
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  - Foster, W. L., L. Roberts, R. E. McLendon, and R. C. Hill. “Localized peribronchial thickening: a CT sign of occult bronchogenic carcinoma.” Ajr Am J Roentgenol 144, no. 5 (May 1985): 906–8. https://doi.org/10.2214/ajr.144.5.906.
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  - McLendon, R. E., P. C. Burger, L. F. Eng, C. J. Wikstrand, C. N. Pegram, and D. D. Bigner. “PRODUCTION AND CHARACTERIZATION OF 3 MONOCLONAL ANTIBODIES (MAs) TO GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP).” Journal of Neuropathology and Experimental Neurology 44, no. 3 (May 1985): 331–331. https://doi.org/10.1097/00005072-198505000-00083.
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  - BIGNER, S. H., R. E. MCLENDON, D. W. MENSI, C. J. WIKSTRAND, C. N. PEGRAM, W. W. JOHNSTON, and D. D. BIGNER. “EXPRESSION OF GLIAL FIBRILLARY ACIDIC PROTEIN IN CYTOLOGIC SPECIMENS FROM THE CENTRAL NERVOUS-SYSTEM AS DEMONSTRATED BY MONOCLONAL-ANTIBODIES.” Acta Cytologica 29, no. 5 (January 1, 1985): 919–20.
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  - MCLENDON, R. E., B. J. CRAIN, and P. C. BURGER. “POLYMICROGYRIA IN THE CHIARI TYPE-II (ARNOLD-CHIARI) MALFORMATION.” Laboratory Investigation 52, no. 1 (January 1, 1985): P6–P6.
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  - MCLENDON, R. E., J. A. TUCKER, J. D. SHELBURNE, P. INGRAM, and F. S. VOGEL. “A MICROPROBE - HISTOCHEMICAL ANALYSIS OF INTRAPARENCHYMAL CENTRAL NERVOUS-SYSTEM MINERALIZATION.” Laboratory Investigation 52, no. 1 (January 1, 1985): A42–43.
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  - McLendon, R. E., B. J. Crain, W. J. Oakes, and P. C. Burger. “Cerebral polygyria in the Chiari Type II (Arnold-Chiari) malformation.” Clin Neuropathol 4, no. 5 (1985): 200–205.
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  - Sickles, D. W., and R. E. McLendon. “Metabolic variation among rat lumbosacral alpha-motoneurons.” Histochemistry 79, no. 2 (1983): 205–17. https://doi.org/10.1007/BF00489782.
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  - Sickles, D. W., R. E. McLendon, and T. H. Rosenquist. “Alternative method for quantitative enzyme histochemistry of muscle fibers. Application of photographic densitometry combined with atomic absorption spectrophotometry.” Histochemistry 73, no. 4 (1982): 577–88. https://doi.org/10.1007/BF00493370.
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- Book Sections
  - McLendon, R., and T. J. Cummings. “Neuropathology of gliomas.” In The Duke Glioma Handbook: Pathology, Diagnosis, and Management, 146–68, 2016. https://doi.org/10.1017/CBO9781107588721.008.
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  - Buckley, A. F., R. E. McLendon, C. J. Wikstrand, and D. D. Bigner. “Biomarker discovery in central nervous system neoplasms: Past, present and future.” In Tumors of the Central Nervous System: Astrocytomas, Hemangioblastomas, and Gangliogliomas, 5:107–19, 2012. https://doi.org/10.1007/978-94-007-2019-0_13.
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  - McLendon, R. E., A. H. Friedman, and L. Gray. “Glioblastoma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 103–30, 2006.
  - McLendon, R. E., J. M. Kros, J. Bruner, and L. Gray. “Oligodendroglioma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 167–86, 2006.
  - McLendon, R. E., J. M. Kros, L. Gray, and J. Bruner. “Anaplastic oligodendroglioma and mixed glioma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 187–200, 2006.
  - McLendon, R. E., J. M. Provenzale, and A. H. Friedman. “Astrocytoma of the spinal cord.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 97–102, 2006.
  - McLendon, R. E., J. M. Provenzale, and A. H. Friedman. “Anaplastic astrocytoma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 75–88, 2006.
  - McLendon, R. E., J. M. Provenzale, and A. H. Friedman. “Astrocytoma of the brainstem.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 89–96, 2006.
  - McLendon, R. E., L. Gray, L. M. Shah, and A. H. Friedman. “Pleomorphic xanthoastrocytoma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 131–56, 2006.
  - McLendon, R. E., L. Gray, L. Shah, and A. H. Friedman. “Diffuse astrocytoma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 57–74, 2006.
  - McLendon, R. E., and L. Gray. “Supratentorial primitive neuroectodermal tumor: Neuroblastoma, ganglioneuroblastoma, malignant neuroblastic – glial tumor and ependymoblastoma.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 291–304, 2006.
  - McLendon, R. E., and P. Kleihues. “Classification of tumors of the nervous system: An historical annotation.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 1–10, 2006.
  - McLendon, R. E., and T. J. Cummings. “Ectopias and hamartomas.” In Russell and Rubinstein’s Pathology of Tumors of the Nervous System., 613–21, 2006.
- Other Articles
  - Rasheed, B. K., R. E. McLendon, H. S. Friedman, A. H. Friedman, H. E. Fuchs, D. D. Bigner, and S. H. Bigner. “Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.” Oncogene, June 1, 1995.
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  - Lee, V. S., J. M. Provenzale, H. E. Fuchs, A. Osumi, and R. E. McLendon. “Post-traumatic epidermoid cyst: CT appearance.” J Comput Assist Tomogr, 1995. https://doi.org/10.1097/00004728-199501000-00032.
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  - Furie, D. M., G. J. Felsberg, R. D. Tien, H. S. Friedman, H. Fuchs, and R. McLendon. “MRI of gangliocytoma of cerebellum and spinal cord.” J Comput Assist Tomogr, 1993. https://doi.org/10.1097/00004728-199305000-00031.
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- Conference Papers
  - Sampson, John H., Kristen A. Batich, Duane Anthony Mitchell, James Emmett Herndon, Gloria Broadwater, Patrick Healy, Luis Sanchez-Perez, et al. “Reproducibility of outcomes in sequential trials using CMV-targeted dendritic cell vaccination for glioblastoma.” In Journal of Clinical Oncology, Vol. 40, 2022.
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  - Batich, Kristen, Duane Mitchell, Patrick Healy, James Herndon, Gloria Broadwater, Gunn Michael, Min-Nung Huang, et al. “CTIM-10. REPRODUCIBILITY OF CLINICAL TRIALS USING CMV-TARGETED DENDRITIC CELL VACCINES IN PATIENTS WITH GLIOBLASTOMA.” In Neuro Oncology, 23:vi51–vi51. Oxford University Press (OUP), 2021. https://doi.org/10.1093/neuonc/noab196.202.
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  - Chandramohan, Vidyalakshmi, Tyler Evangelous, Eric S. Lipp, Bhavna Hora, Darell D. Bigner, Roger E. McLendon, and David M. Ashley. “ANALYSIS OF IMMUNE SIGNATURES IN PEDIATRIC GLIOBLASTOMAS FOR PATIENT STRATIFICATION TO IMMUNOTHERAPY.” In Neuro Oncology, 22:365–365, 2020.
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  - Tan, Char Loo, Daniel Landi, Herbert Fuchs, and Roger E. McLendon. “A novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10 year-old boy with 10 years of follow-up.” In Brain Pathology, 29:157–157. WILEY, 2019.
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  - Pirozzi, Christopher J., Catherine Y. Wang, Austin B. Carpenter, Huishan Zhu, Paula K. Greer, Roger E. McLendon, Darell D. Bigner, Yiping He, and Hai Yan. “Abstract 63: Driving brain tumorigenesis: Generation of a mutant IDH1 mouse model of progressive glioma.” In Cancer Research, 74:63–63. American Association for Cancer Research (AACR), 2014. https://doi.org/10.1158/1538-7445.am2014-63.
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  - Cheng, S., H. Feng, G. Y. Lopez, C. K. Kim, C. G. Duncan, A. Alvarez, R. Nishikawa, et al. “EGFR PHOSPHORYLATION OF DCBLD2 RECRUITS TRAF6 AND STIMULATES AKT-PROMOTED TUMORIGENESIS.” In Neuro Oncology, 16:iii16–17. Oxford University Press (OUP), 2014. https://doi.org/10.1093/neuonc/nou206.60.
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  - Guo, Changcun, Lee H. Chen, Yafen Huang, Chun-chi Chang, Ping Wang, Christopher J. Pirozzi, Xiaoxia Qin, et al. “MLL2 maintains neoplastic cell growth and global histone H3 lysine 4 monomethylation.” In Cancer Research, Vol. 74, 2014. https://doi.org/10.1158/1538-7445.AM2014-LB-82.
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  - Fangusaro, Jason, Sridharan Gururangan, Tina Young Poussaint, Roger E. McLendon, Arzu Onar-Thomas, Katherine E. Warren, Shengjie Wu, et al. “Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022).” In Cancer, 119:4180–87, 2013. https://doi.org/10.1002/cncr.28343.
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  - Gagnon, R., H. Yan, A. B. Rasheed, R. E. McLendon, P. J. Killella, Z. J. Reitman, M. B. Datto, and S. Sebastian. “Development and Validation of a Clinical Molecular Diagnostic Test for TERT Gene Promoter Mutations C250T and C228T.” In Journal of Molecular Diagnostics, 15:920–920. ELSEVIER SCIENCE INC, 2013.
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  - Hall, Peter E., Meizhang Li, Joseph Gallagher, James S. Hale, Qiulian Wu, Monica Venere, Emily Levy, et al. “NICHE DERIVED EXTRACELLULAR MATRIX CUES ARE PIVOTAL FOR GLIOBLASTOMA STEM CELL GROWTH AND MAINTENANCE.” In Neuro Oncology, 14:143–143. OXFORD UNIV PRESS INC, 2012.
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  - Kulig, Kimary, Roger E. McLendon, Susan C. Locke, Debra R. Young, Xiaoyin Zhong, Lori L. Hudson, and Amy Pickar Abernethy. “MET and ALK in glioblastoma multiforme (GBM): Comparison of IHC and FISH.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.
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  - Jiang, X., D. A. Reardon, A. Desjardins, J. J. Vredenburgh, J. A. Quinn, A. D. Austin, J. E. Herndon, R. E. McLendon, and H. S. Friedman. “O6-Methylguanine-DNA Methytransferase (MGMT) Immunohistochemistry as a Predictor of Resistance to Temozolomide in Primary CNS Lymphoma.” In Laboratory Investigation, 91:382A-382A. NATURE PUBLISHING GROUP, 2011.
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  - Brennan, Cameron W., Daniel J. Brat, Kenneth D. Aldape, Mark Cohen, Norman L. Lehman, Roger E. McLendon, Ryan Miller, Matt Schniederjan, and Scott R. Vandenberg. “ADDITION OF GBM HISTOLOGICAL FEATURES AND EGFRVIII EXPRESSION TO THE CANCER GENOME ATLAS: PHENOTYPIC CORRELATES OF MOLECULAR SUBCLASSES.” In Neuro Oncology, 12:67–68. OXFORD UNIV PRESS INC, 2010.
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  - Mitchell, Duane A., Gary E. Archer, Darell D. Bigner, Henry S. Friedman, Denise Lally-Goss, Beth Perry, James E. Herndon, et al. “RNA Transfected Dendritic Cell Vaccines Targeting Human Cytomegalovirus Antigens in Patients with Glioblastoma.” In Molecular Therapy, 17:S93–S93. NATURE PUBLISHING GROUP, 2009.
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  - Affronti, M. L., J. M. Day, J. E. Herndon, J. N. Rich, J. A. Quinn, D. A. Reardon, J. J. Vredenburgh, A. Desjardins, R. E. McLendon, and H. S. Friedman. “Radiation and concurrent temozolomide followed by rotational multi-agent chemotherapy for glioblastoma (GBM) patients.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.
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  - Bao, Shideng, Qiulian Wu, Sith Sathornsumetee, Yueling Hao, Zhizhong Li, Anita B. Hjelmeland, Qing Shi, Roger E. McLendon, Darell D. Bigner, and Jeremy N. Rich. “Glioma cancer stem cells promote tumor angiogenesis through vascular endothelial growth factor.” In Neuro Oncology, 8:392–392. DUKE UNIV PRESS, 2006.
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  - Sathornsumetee, Sith, Anita B. Hjelmeland, Stephen T. Keir, Roger E. McLendon, David Batt, Timothy Ramsey, Naeem Yusuff, et al. “AAL881, a novel small molecule inhibitor of RAF and VEGFR activities, blocks growth of malignant glioma.” In Neuro Oncology, 8:417–417. DUKE UNIV PRESS, 2006.
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  - Gregory, S. G., N. V. Johnson, J. J. Connelly, J. Virgadamo, R. E. McLendon, J. M. Vance, and D. D. Bigner. “Characterizing genomic rearrangements in oligodendroglioma using whole genome tilepath hrCGH arrays.” In Neuro Oncology, 8:421–421. DUKE UNIV PRESS, 2006.
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  - Adamson, D Cory, Chunhui Di, Qun Shi, Roger E. McLendon, Darell D. Bigner, and Hai Yan. “Prognostic significance of OTX2 in medulloblastoma.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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  - Maxwell, Jill A., Stewart P. Johnson, Roger E. McLendon, Francis Ali-Osman, Jennifer A. Quinn, Allan H. Friedman, James E. Herndon, et al. “O-6-alkylguanine-DNA alkyltransferase (AGT) and microsatellite instability (MSI) analyses in malignant glioma.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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  - Johnson, Nicole V., Jessica J. Connelly, Josh Virigadamo, Roger E. McLendon, Jeffrey M. Vance, Darell D. Bigner, and Simon G. Gregory. “Characterizing oligodendroglioma rearrangements using whole genome hrCGH arrays.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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  - Adamson, D. C., D. K. Broderick, C. Di, Y. R. Samuels, R. E. McLendon, D. W. Fults, V. E. Velculescu, A. Rasheed, D. D. Bigner, and H. Yan. “PIK3CA is mutated in oligodendrogliomas, astrocytomas, and medulloblastomas and associated with chromosome 1p, 19q LOH in oligodendrogliomas.” In Neuro Oncology, 7:345–345. DUKE UNIV PRESS, 2005.
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  - Gondar, R. K., M. D. Hjelmeland, S. T. Keir, C. A. Conrad, R. E. McLendon, C. J. Wikstrand, P. Traxler, et al. “Inhibition of receptor tyrosine kinases and mammalian target of rapamycin offers combinatorial benefit in tumor control.” In Neuro Oncology, 6:407–407. DUKE UNIV PRESS, 2004.
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  - Mitchell, D. A., C. Learn, R. Schmittling, A. Friedman, R. E. McLendon, D. D. Bigner, and J. H. Sampson. “Detection and immunologic recognition of cytomegalovirus antigens expressed within malignant gliomas.” In Neuro Oncology, 6:343–343. DUKE UNIV PRESS, 2004.
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  - Mott, R. T., K. C. Turner, and R. E. McLendon. “Fish markers in diffuse astrocytomas.” In Journal of Neuropathology and Experimental Neurology, 63:538–538. AMER ASSN NEUROPATHOLOGISTS INC, 2004.
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  - McLendon, R. E., R. N. Wiltshire, J. E. Herndon, A. Lloyd, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “Sub-classification of glioblastoma defined by comparative genomic hybridization alterations.” In Journal of Neuropathology and Experimental Neurology, 62:542–542. AMER ASSN NEUROPATHOLOGISTS INC, 2003.
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  - Rich, J. N., C. H. Guo, R. E. McLendon, D. D. Bigner, X. F. Wang, and C. M. Counter. “Biological model for assessing the role in glioma formation of genes differentially expressed in human gliomas.” In Annals of Neurology, 50:S31–S31. WILEY-LISS, 2001.
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  - Cummings, T. J., K. R. Bulsara, R. E. McLendon, H. E. Fuchs, and T. M. George. “Pathology of the normal versus the tethered filum terminale.” In Journal of Neuropathology and Experimental Neurology, 60:553–553. AMER ASSN NEUROPATHOLOGISTS INC, 2001.
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  - McLendon, R. E., H. S. Friedman, D. C. Lonuee, H. E. Fuchs, and R. B. Hessler. “SYNCHRONOUS EPENDYMO-GLIOMAS.” In Journal of Neuropathology and Experimental Neurology, 54:422–422. Oxford University Press (OUP), 1995. https://doi.org/10.1097/00005072-199505000-00062.
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  - KLITZMAN, B., N. SCHRADER, R. E. MCLENDON, and M. W. DEWHIRST. “QUANTITATIVE MORPHOLOGY OF RAT CARCINOMA WITH RELEVANCE TO OXYGENATION.” In Faseb Journal, 8:A1046–A1046. FEDERATION AMER SOC EXP BIOL, 1994.
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  - Archer, G. E., J. M. Schuster, H. E. Fuchs, A. Guaspari, D. P. Bigner, H. S. Friedman, and R. E. McLendon. “NEUROPATHOLOGY OF MULTIPLE VERSUS SINGLE DOSE INTRATHECAL MELPHALAN IN RATS.” In Journal of Neuropathology and Experimental Neurology, 52:298–298. Oxford University Press (OUP), 1993. https://doi.org/10.1097/00005072-199305000-00152.
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