Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of North Carolina - Chapel Hill 2010
• Expertise
• 

  Subject Headings

  • Insulin--Methylation
  • Methylation
• Research
• 

  Selected Grants

  • Early Life Adversity and the Developmental Programming of Early Childhood Telomere Biology: A Longitudinal Study of Developmental Context and Behavioral Mediators awarded by National Institutes of Health 2021 - 2026
  • Skeletal Muscle Molecular Drug Targets for Exercise-induced Cardiometabolic Health awarded by National Institutes of Health 2020 - 2025
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Jiang R, Hauser ER, Kwee LC, Shah SH, Regan JA, Huebner JL, et al. The association of accelerated epigenetic age with all-cause mortality in cardiac catheterization patients as mediated by vascular and cardiometabolic outcomes. Clin Epigenetics. 2022 Dec 3;14(1):165.
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    • Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, et al. Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Med. 2021 Apr 30;13(1):74.
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    • Jiang R, Babyak MA, Brummett BH, Siegler IC, Kuhn CM, Williams RB. Corrigendum to "Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress" [Psychoneuroendocrinology 79 (2017) (May) 13-19]. Psychoneuroendocrinology. 2020 Nov;121:104861.
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    • Singh A, Babyak MA, Sims M, Musani SK, Brummett BH, Jiang R, et al. Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants. Transl Psychiatry. 2020 Oct 20;10(1):351.
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    • Brummett BH, Babyak MA, Jiang R, Huffman KM, Kraus WE, Singh A, et al. Systolic Blood Pressure and Socioeconomic Status in a large multi-study population. Ssm Popul Health. 2019 Dec;9:100498.
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    • Brummett BH, Babyak MA, Singh A, Hauser ER, Jiang R, Huffman KM, et al. Lack of Association of a Functional Polymorphism in the Serotonin Receptor Gene With Body Mass Index and Depressive Symptoms in a Large Meta-Analysis of Population Based Studies. Front Genet. 2018;9:423.
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    • Jiang R, Babyak MA, Brummett BH, Hauser ER, Shah SH, Becker RC, et al. Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort. Am Heart J. 2017 Aug;190:40–5.
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    • Jiang R, Babyak MA, Brummett BH, Siegler IC, Kuhn CM, Williams RB. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress. Psychoneuroendocrinology. 2017 May;79:13–9.
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    • Singh A, Babyak MA, Brummett BH, Jiang R, Watkins LL, Barefoot JC, et al. Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene. Genet Epidemiol. 2015 Sep;39(6):489–97.
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    • Singh A, Babyak MA, Nolan DK, Brummett BH, Jiang R, Siegler IC, et al. Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene. Eur J Hum Genet. 2015 Jun;23(6):854–62.
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    • Brummett BH, Babyak MA, Williams RB, Harris KM, Jiang R, Kraus WE, et al. A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress. Plos One. 2014;9(12):e114451.
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    • Jiang R, Brummett BH, Hauser ER, Babyak MA, Siegler IC, Singh A, et al. Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. Biol Psychol. 2013 Apr;93(1):184–9.
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    • Jiang R, Brummett BH, Babyak MA, Siegler IC, Williams RB. Brain-derived neurotrophic factor (BDNF) Val66Met and adulthood chronic stress interact to affect depressive symptoms. J Psychiatr Res. 2013 Feb;47(2):233–9.
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    • Brummett BH, Babyak MA, Jiang R, Shah SH, Becker RC, Haynes C, et al. A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events. Plos One. 2013;8(12):e82781.
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    • Brummett BH, Babyak MA, Singh A, Jiang R, Williams RB, Harris KM, et al. Socioeconomic indices as independent correlates of C-reactive protein in the National Longitudinal Study of Adolescent Health. Psychosom Med. 2013;75(9):882–93.
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    • Jiang R, French JE, Stober VP, Kang-Sickel J-CC, Zou F, Nylander-French LA. Single-Nucleotide Polymorphisms Associated with Skin Naphthyl–Keratin Adduct Levels in Workers Exposed to Naphthalene. Environmental Health Perspectives. 2012 Jun;120(6):857–64.
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    • Babyak MA, Schwartz S, Jiang R, Brummett B, Kauwe JS, Corcoran C, et al. PSYCHOSOCIAL STRESS IN MIDLIFE MAY MODERATE EFFECTS OF APOE-TOMM40 RS157580 ON METABOLIC TRAITS IN LATE LIFE. Annals of Behavioral Medicine. 2012 Apr 1;43:S180–S180.
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    • Jiang R, Harwood JJ. A field study of the fates of Arsenal and Escort Applied on the Cumberland Plateau in Tennessee. American Journal of Environmental Sciences. 65:463–9.

  • Conference Papers

    • Brummett B, Jiang R, Singh A, Hauser E, Babyak M, Siegler I, et al. COMT VAL158MET (RS4680) GENOTYPES MODERATE THE ASSOCIATION BETWEEN CAREGIVER STRESS AND THE CORTISOL AWAKENING RESPONSE. In: Annals of Behavioral Medicine. OXFORD UNIV PRESS INC; 2018. p. S367–S367.
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    • Singh A, Hauser ER, Johnson JL, Babyak MA, Brummett BH, Jiang R, et al. Follow-up of GxE Interactions: EBF1 GxE Association, Synthetic Chronic Psychosocial Stress, and Dropout from a Structured Exercise Program. In: Genetic Epidemiology. WILEY-BLACKWELL; 2016. p. 662–3.
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    • Williams RB, Georgiades A, Brummett BH, Babyak MA, Jiang R, Shah SH, et al. DRD2 SNP RS4586205, CHD METABOLIC RISK FACTORS IN NORMALS AND CLINICAL COURSE IN CHD PATIENTS. In: International Journal of Behavioral Medicine. SPRINGER; 2014. p. S52–S52.
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    • Babyak MA, Becker RC, Helms MJ, Jiang R, Singh A, Brummett BH, et al. ADRENERGIC GENE VARIANTS ARE ASSOCIATED WITH PLATELET AGGREGATION TO EPINEPHRINE. In: Psychosomatic Medicine. LIPPINCOTT WILLIAMS & WILKINS; 2013. p. A87–A87.
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    • Brummett BH, Babyak MA, Jiang R, Singh A, Williams RB, Harris KM, et al. BIOBEHAVIORAL MEDIATORS OF SES EFFECTS ON CRP IN A NATIONALLY REPRESENTATIVE US SAMPLE. In: Psychosomatic Medicine. LIPPINCOTT WILLIAMS & WILKINS; 2013. p. A70–1.
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