Skip to main content

Ronette L Kolotkin

Adjunct Professor in the Department of Family Medicine and Community Health
Family Medicine and Community Health, Diet & Fitness Center
Duke Box 3829, Durham, NC 27710
2100 Erwin Rd, Durham, NC 27705

Selected Publications


Effect of semaglutide 2.4 mg on physical functioning and weight- and health-related quality of life in adults with overweight or obesity: Patient-reported outcomes from the STEP 1-4 trials.

Journal Article Diabetes Obes Metab · July 2024 AIMS: To summarize the effects of semaglutide 2.4 mg on weight-related quality of life (WRQOL) and health-related quality of life (HRQOL), focusing on the confirmatory secondary endpoint of physical functioning. MATERIALS AND METHODS: The STEP 1-4 Phase 3a ... Full text Link to item Cite

Effect of once-weekly subcutaneous semaglutide 2.4 mg on weight- and health-related quality of life in an East Asian population: Patient-reported outcomes from the STEP 6 trial.

Journal Article Clin Obes · August 2023 We assessed the effect of semaglutide 2.4 and 1.7 mg versus placebo on weight-related quality of life (WRQOL) and health-related quality of life (HRQOL) in the STEP 6 trial. Adults from East Asia (body mass index [BMI] ≥27.0 kg/m2 with ≥2 weight-related co ... Full text Link to item Cite

Patient-reported outcomes, weight loss, and remission of type 2 diabetes 3 years after gastric bypass and sleeve gastrectomy (Oseberg); a single-centre, randomised controlled trial.

Journal Article Lancet Diabetes Endocrinol · August 2023 BACKGROUND: Little is known about the comparative effects of various bariatric procedures on patient-reported outcomes. We aimed to compare 3-year effects of gastric bypass and sleeve gastrectomy on patient-reported outcome measures in patients with obesit ... Full text Link to item Cite

Development of an Assessment Tool for Completion by Patients with Overweight or Obesity.

Journal Article Adv Ther · January 2023 INTRODUCTION: Discussions of weight-management strategies between patients and healthcare providers can yield positive outcomes for people with overweight or obesity. Nonetheless, people with overweight or obesity encounter communication challenges and oth ... Full text Link to item Cite

Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy.

Journal Article Int J Obes (Lond) · April 2022 BACKGROUND/OBJECTIVES: There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and comorbidities. We aimed to determin ... Full text Link to item Cite

Effect of aerobic exercise intensity on health-related quality of life in severe obesity: a randomized controlled trial.

Journal Article Health Qual Life Outcomes · February 24, 2022 BACKGROUND: Aerobic exercise is an important part of obesity treatment and may improve health-related quality of life (HRQOL). The objective of this study was to compare the effect of two different exercise programs on health-related quality of life in pat ... Full text Link to item Cite

The Norse Feedback in a population of patients undergoing bariatric surgery-Psychometric properties of a digital computer-adaptive questionnaire assessing mental health.

Journal Article Clin Obes · February 2022 The Norse Feedback (NF) is a questionnaire developed for patient-reported outcome monitoring with a clinical feedback system (PRO/CFS). As mental health is a concern after bariatric surgery, the use of the NF as part of PRO/CFS may be beneficial. The aim o ... Full text Link to item Cite

Confirmatory psychometric evaluations of the Impact of Weight on Quality of Life-Lite Clinical Trials Version (IWQOL-Lite-CT).

Journal Article Clin Obes · October 2021 The Impact of Weight on Quality of Life-Lite Clinical Trials Version (IWQOL-Lite-CT) was developed to assess weight-related physical and psychosocial functioning in the context of clinical trials. Data from two pivotal trials of once-weekly subcutaneous se ... Full text Link to item Cite

Mediators of suicidality 12 years after bariatric surgery relative to a nonsurgery comparison group.

Journal Article Surg Obes Relat Dis · January 2021 BACKGROUND: Individuals undergoing bariatric surgery report higher levels of suicidality than the general population, but it is unknown what mediates this phenomenon or how this compares with individuals with severe obesity not receiving surgery. OBJECTIVE ... Full text Link to item Cite

Erosive Esophagitis and Symptoms of Gastroesophageal Reflux Disease in Patients with Morbid Obesity with and without Type 2 Diabetes: a Cross-sectional Study.

Journal Article Obes Surg · July 2020 BACKGROUND: Type 2 diabetes (T2DM) is associated with gastroesophageal reflux disease (GERD) in the general population, but the relationship between these conditions in candidates for bariatric surgery is uncertain. We compared the prevalence of GERD and t ... Full text Link to item Cite

A novel patient-reported outcome monitoring with clinical feedback system in bariatric surgery care: study protocol, design and plan for evaluation.

Journal Article BMJ Open · June 22, 2020 BACKGROUND: Consultations before and after bariatric surgery should include structured assessments of patients' health-related quality of life (HRQOL) and mental health. One way to conduct this assessment is to implement patient-reported outcome monitoring ... Full text Link to item Cite

Overall Treatment Satisfaction 5 Years After Bariatric Surgery.

Journal Article Obes Surg · January 2020 INTRODUCTION: Up to 30 % of patients undergoing bariatric surgery are dissatisfied with treatment outcomes in the long term. The aim of this study was to examine overall satisfaction with treatment 5 years after bariatric surgery and its association with b ... Full text Link to item Cite

Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study.

Journal Article BMJ Open · September 12, 2019 OBJECTIVES: Sleeve gastrectomy (SG) is the most frequently performed bariatric surgery procedure worldwide, but reports on long-term quality of life (QOL) outcomes are scarce. We investigated 5-year trajectories in QOL and their associations with weight lo ... Full text Link to item Cite

Patient-reported quality of life with obesity - development of a new measurement scale.

Journal Article Tidsskr Nor Laegeforen · August 20, 2019 BACKGROUND: Many questionnaires for measuring the quality of life for patients with obesity require comprehensive calculation before they are used. There is a need for questionnaires that permit simple assessment of the responses during a patient consultat ... Full text Link to item Cite

Single-centre, triple-blinded, randomised, 1-year, parallel-group, superiority study to compare the effects of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes and β-cell function in subjects with morbid obesity: a protocol for the Obesity surgery in Tønsberg (Oseberg) study.

Journal Article BMJ Open · June 4, 2019 INTRODUCTION: Bariatric surgery is increasingly recognised as an effective treatment option for subjects with type 2 diabetes and obesity; however, there is no conclusive evidence on the superiority of Roux-en-Y gastric bypass or sleeve gastrectomy. The Os ... Full text Link to item Cite

Changes in Sexual Functioning in Women and Men in the 5 Years After Bariatric Surgery.

Journal Article JAMA Surg · June 1, 2019 IMPORTANCE: Short-term improvements in sexual functioning are reported after bariatric surgery, but to our knowledge, little is known about the durability of these improvements. OBJECTIVE: To determine the percentage of adults with impairment in sexual fun ... Full text Link to item Cite

Validation of a new measure of quality of life in obesity trials: Impact of Weight on Quality of Life-Lite Clinical Trials Version.

Journal Article Clin Obes · June 2019 The Impact of Weight on Quality of Life-Lite (IWQOL-Lite) is widely used in evaluations of weight-loss interventions, including pharmaceutical trials. Because this measure was developed using input from individuals undergoing intensive residential treatmen ... Full text Open Access Link to item Cite

Changes in Sexual Functioning in Women and Men in the 5 Years after Bariatric Surgery

Journal Article Obstetrical and Gynecological Survey · June 1, 2019 Full text Cite

Implications of differing attitudes and experiences between providers and persons with obesity: results of the national ACTION study.

Journal Article Postgrad Med · June 2019 Objective: Our aim was to explore how differing attitudes, expectations, and experiences among people with obesity (PwO) and healthcare providers (HCPs) might have an impact on effectively implementing current obesity treatment guidelines. Methods: Online ... Full text Link to item Cite

A call to action to inform patient-centred approaches to obesity management: Development of a disease-illness model.

Journal Article Clin Obes · June 2019 Patient-centred care is an essential component of high-quality health care, shown to improve clinical outcomes and patient satisfaction, and reduce costs. While there are several authoritative models of obesity pathophysiology and treatment algorithms, a t ... Full text Link to item Cite

Health-related quality of life after camp-based family obesity treatment: An RCT

Journal Article BMJ Paediatrics Open · April 1, 2019 Objective To compare the effects of a 2-year camp-based immersion family treatment for obesity with an outpatient family-based treatment for obesity on health-related quality of life (HRQoL) in two generations. Design Randomised controlled trial. Setting R ... Full text Cite

Effects of a physical activity intervention on schoolchildren's health-related quality of life: The active smarter kids (ASK) cluster-randomized controlled trial

Journal Article Preventive Medicine Reports · March 1, 2019 We investigated whether a seven-month (November 2014 to June 2015), school-based cluster-randomized controlled physical activity intervention improved health-related quality of life (HRQoL) in 10-year old children. The participants (N = 1229) from 57 eleme ... Full text Cite

Eating self-efficacy as predictor of long-term weight loss and obesity-specific quality of life after sleeve gastrectomy: A prospective cohort study.

Journal Article Surg Obes Relat Dis · February 2019 BACKGROUND: A person's confidence to control eating, eating self-efficacy (ESE), has been identified as a target for long-term weight management in nonsurgical weight loss interventions, but has to a limited extent been studied after bariatric surgery. OBJ ... Full text Link to item Cite

A review of systematic reviews on the effects of patient-reported outcome monitoring with clinical feedback systems on health-related quality of life-implications for a novel technology in obesity treatment.

Journal Article Clinical obesity · December 2018 Patient-reported outcome monitoring with clinical feedback systems (PRO/CFS) has been employed in many disease states to measure and improve health-related quality of life (HRQOL). Exploring the role of PRO/CFS in treatment for obesity may prove valuable. ... Full text Cite

12-year trajectory of health-related quality of life in gastric bypass patients versus comparison groups.

Journal Article Surg Obes Relat Dis · September 2018 BACKGROUND: Few prospective studies compare long-term health-related quality of life (HRQOL) outcomes between bariatric surgery patients and individuals with severe obesity who do not undergo bariatric surgery. OBJECTIVES: This 12-year, prospective study e ... Full text Link to item Cite

Patient-Reported Outcome Measures 2 Years After Standard and Distal Gastric Bypass-a Double-Blind Randomized Controlled Trial.

Journal Article Obes Surg · March 2018 BACKGROUND: The preferred surgical procedure for treating morbid obesity is debated. Patient-reported outcome measures (PROMs) are relevant for evaluation of the optimal bariatric procedure. METHODS: A total of 113 patients with BMI from 50 to 60 were rand ... Full text Link to item Cite

Improvements in health-related quality of life over 3 years with liraglutide 3.0 mg compared with placebo in participants with overweight or obesity.

Journal Article Clin Obes · February 2018 Previously in the SCALE Obesity and Prediabetes trial, at 1 year, participants with obesity (or overweight with comorbidities) and prediabetes receiving liraglutide 3.0 mg experienced greater improvements in health-related quality of life (HRQoL) than thos ... Full text Link to item Cite

Perceptions of Barriers to Effective Obesity Care: Results from the National ACTION Study.

Journal Article Obesity (Silver Spring) · January 2018 OBJECTIVE: ACTION (Awareness, Care, and Treatment in Obesity maNagement) examined obesity-related perceptions, attitudes, and behaviors among people with obesity (PwO), health care providers (HCPs), and employer representatives (ERs). METHODS: A total of 3 ... Full text Link to item Cite

Health-related quality of life in randomized controlled trials of lorcaserin for obesity management: what mediates improvement?

Journal Article Clin Obes · December 2017 Lorcaserin, plus diet and exercise, has demonstrated significant weight loss and improved cardiometabolic parameters vs. placebo in patients with overweight/obesity in three randomized, placebo-controlled trials. We examined whether lorcaserin is also asso ... Full text Link to item Cite

Correlates of weight-related quality of life among individuals with binge eating disorder before and after cognitive behavioral therapy.

Journal Article Eat Behav · December 2017 Individuals with obesity and binge eating disorder (BED) report poorer weight-related quality of life (WRQOL) compared to individuals with obesity alone. Cognitive behavioral therapy (CBT), the best available treatment for BED, does not consistently produc ... Full text Link to item Cite

Associations between health-related quality of life, cardiorespiratory fitness, muscle strength, physical activity and waist circumference in 10-year-old children: the ASK study.

Journal Article Qual Life Res · December 2017 PURPOSE: To examine the associations between cardiorespiratory fitness, muscle strength, physical activity and waist circumference with self-reported health-related quality of life (HRQoL) in children. METHODS: We conducted a cross-sectional analysis that ... Full text Link to item Cite

Development of a clinical trials version of the Impact of Weight on Quality of Life-Lite questionnaire (IWQOL-Lite Clinical Trials Version): results from two qualitative studies.

Journal Article Clin Obes · October 2017 Existing measures of health-related quality of life and patient functioning in obesity, such as the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire, lack the developmental rigour required by the Food and Drug Administration (FDA) to sup ... Full text Open Access Link to item Cite

A systematic review of reviews: exploring the relationship between obesity, weight loss and health-related quality of life.

Journal Article Clin Obes · October 2017 This is the first systematic review of reviews to assess the effect of obesity and weight loss on health-related quality of life (HRQoL). We identified 12 meta-analyses/systematic reviews published between January 2001 and July 2016. They addressed the fol ... Full text Open Access Link to item Cite

Weight and Metabolic Outcomes 12 Years after Gastric Bypass.

Journal Article N Engl J Med · September 21, 2017 BACKGROUND: Few long-term or controlled studies of bariatric surgery have been conducted to date. We report the 12-year follow-up results of an observational, prospective study of Roux-en-Y gastric bypass that was conducted in the United States. METHODS: A ... Full text Link to item Cite

Five-Year Outcomes After Vertical Sleeve Gastrectomy for Severe Obesity: A Prospective Cohort Study.

Journal Article Obes Surg · August 2017 BACKGROUND: We present 5-year outcomes after vertical sleeve gastrectomy (VSG), including complications and revisions, weight change, obesity-related diseases and health-related quality of life (HRQOL). METHODS: Patients operated from December 2005 to Nove ... Full text Link to item Cite

Sexual functioning of men and women with severe obesity before bariatric surgery.

Journal Article Surg Obes Relat Dis · February 2017 BACKGROUND: Obesity may impair sexual function through multiple mechanisms, but little is known about sexual dysfunction among adults with severe obesity seeking bariatric procedures. OBJECTIVES: To describe sexual function and associated factors before ba ... Full text Link to item Cite

Improvements in health-related quality of life with liraglutide 3.0 mg compared with placebo in weight management.

Journal Article Clin Obes · August 2016 Obesity has a negative impact on health-related quality of life (HRQoL). The SCALE Obesity and Prediabetes study investigated the effect of liraglutide 3.0 mg, as adjunct to diet and exercise, on HRQoL in patients with obesity [body mass index (BMI) ≥ 30 k ... Full text Link to item Cite

Improvements in Functional Exercise Capacity after a Residential Behavioural Change, Diet and Fitness Program for Obese Adults.

Journal Article Physiother Res Int · June 2016 BACKGROUND AND PURPOSE: Obese adults are at an increased risk for mobility-related problems. National guidelines recommend calorie restrictions and exercise for obese adults as a means to improve functional fitness capacity and to increase mobility. Yet, l ... Full text Link to item Cite

Health-related quality of life in two randomized controlled trials of phentermine/topiramate for obesity: What mediates improvement?

Journal Article Qual Life Res · May 2016 PURPOSE: Phentermine/topiramate combination therapy resulted in significant weight loss and improvements in cardiometabolic risk factors in patients with obesity/overweight in two published 56-week randomized, placebo-controlled trials (EQUIP and CONQUER). ... Full text Link to item Cite

Ten-year changes in health-related quality of life after biliopancreatic diversion with duodenal switch.

Journal Article Surg Obes Relat Dis · 2016 BACKGROUND: Long-term data on health-related quality of life (HRQL) after biliopancreatic diversion with duodenal switch (BPDDS) are scarce. The aim of this study was to evaluate changes in HRQL from baseline to 10 years in patients who had undergone BPDDS ... Full text Link to item Cite

Patient-reported quality of life in a randomized placebo-controlled trial of naltrexone/bupropion for obesity.

Journal Article Clin Obes · October 2015 Weight loss is associated with improved quality of life in some, but not all, weight loss trials. We evaluated changes at 56 weeks in quality of life, measured by the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire, in a pooled analysis ... Full text Link to item Cite

Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.

Journal Article Ann Intern Med · June 16, 2015 BACKGROUND: Choosing a diet rather than being prescribed one could improve weight loss. OBJECTIVE: To examine whether offering choice of diet improves weight loss. DESIGN: Double-randomized preference trial of choice between 2 diets (choice) versus random ... Full text Link to item Cite

Physical activity and quality of life in severely obese adults during a two-year lifestyle intervention programme.

Journal Article J Obes · 2015 It is unknown how changes in physical activity may affect changes in quality of life (QoL) outcomes during lifestyle interventions for severely obese adults. The purpose of this study was to examine associations in the patterns of change between objectivel ... Full text Link to item Cite

Psychosocial functioning before and after surgical treatment for morbid obesity: Reliability and validation of the Norwegian version of obesity-related problemscale

Journal Article PeerJ · January 1, 2015 Background. The aims of this study were to translate the Obesity-Related Problem scale (OP scale) into the Norwegian language and test its reliability, validity and responsiveness in aNorwegian sample. Method. The questionnaire (OP scale) was translated fr ... Full text Cite

Health-related quality of life after bariatric surgery: a systematic review of prospective long-term studies.

Journal Article Surg Obes Relat Dis · 2015 Impaired health-related quality of life (HRQoL) is common in bariatric surgery candidates and is often one of the motivating factors for seeking bariatric surgery. Although many studies have reported changes in HRQoL after bariatric surgery, few are long-t ... Full text Link to item Cite

Factors associated with choice of a low-fat or low-carbohydrate diet during a behavioral weight loss intervention.

Journal Article Appetite · December 2014 Individuals undertaking a weight loss effort have a choice among proven dietary approaches. Factors contributing to choice of either a low-fat/low-calorie diet or a low-carbohydrate diet, two of the most studied and popular dietary approaches, are unknown. ... Full text Link to item Cite

The effects of weight loss after bariatric surgery on health-related quality of life and depression

Journal Article Nutrition and Diabetes · January 1, 2014 Background: In severe obesity, impairments in health-related quality of life (HRQoL) and dysphoric mood are reported. This is a post-surgery analysis of the relationship between HRQoL and depressive symptoms, and weight change after four different types of ... Full text Cite

Obesity and Its Impact Upon Quality of Life

Chapter · January 1, 2014 Obesity may have a negative effect on quality of life (QOL) and is an important outcome in the treatment of obesity. In this chapter we discuss the concept of QOL; the measurement of QOL; the mechanisms by which obesity may influence the physical, social, ... Full text Cite

Five-year changes in health-related quality of life after biliopancreatic diversion with duodenal switch.

Journal Article Obes Surg · October 2013 BACKGROUND: Long-term data of health-related quality of life (HRQL) after biliopancreatic diversion with duodenal switch (BPDDS) procedure are lacking. The aim of this study was to evaluate changes in HRQL from baseline to 5 years after BPDDS. METHODS: Fif ... Full text Link to item Cite

Considering patient diet preference to optimize weight loss: design considerations of a randomized trial investigating the impact of choice.

Journal Article Contemp Clin Trials · May 2013 A variety of diet approaches achieve moderate weight loss in many individuals. Yet, most diet interventions fail to achieve meaningful weight loss in more than a few individuals, likely due to inadequate adherence to the diet. It is widely conjectured that ... Full text Link to item Cite

Weight-related quality of life in Spanish obese subjects suitable for bariatric surgery is lower than in their North American counterparts: a case-control study.

Journal Article Obes Surg · April 2013 BACKGROUND: Obesity impairs quality of life, but the perception of the impairment could be different from one country to another. The purpose was to compare weight-related quality of life (QOL) between cohorts from Spain and North America. METHODS: A cross ... Full text Link to item Cite

Sexual functioning and obesity: a review.

Journal Article Obesity (Silver Spring) · December 2012 We review the literature on the relationship between obesity and sexual functioning. Eleven population-based studies, 20 cross-sectional non-population-based studies, and 16 weight loss studies are reviewed. The consistency of findings suggests that the re ... Full text Link to item Cite

Health benefits of gastric bypass surgery after 6 years.

Journal Article JAMA · September 19, 2012 CONTEXT: Extreme obesity is associated with health and cardiovascular disease risks. Although gastric bypass surgery induces rapid weight loss and ameliorates many of these risks in the short term, long-term outcomes are uncertain. OBJECTIVE: To examine th ... Full text Link to item Cite

Examining the Association Between Body Mass Index and Weight Related Quality of Life in Black and White Women.

Journal Article Appl Res Qual Life · September 2012 Obesity not only increases risk for morbidity/mortality, but also impacts the quality of life of obese individuals. In the United States, black women have the highest prevalence of obesity of any other group with approximately 80% of black women over age 2 ... Full text Link to item Cite

Binge eating and weight-related quality of life in obese adolescents.

Journal Article Nutrients · March 2012 Limited data exist regarding the association between binge eating and quality of life (QOL) in obese adolescent girls and boys. We, therefore, studied binge eating and QOL in 158 obese (BMI ≥ 95th percentile) adolescents (14.5 ± 1.4 years, 68.0% female, 59 ... Full text Link to item Cite

The Relationship Between Weight Loss and Health-related Quality of Life in a Serbian Population.

Journal Article Eur Eat Disord Rev · March 2012 We examined changes in weight-specific health-related quality of life (HRQOL) and the relation to weight loss in a Serbian population undergoing diet-induced weight loss treatment. HRQOL was assessed at intake and after 1 year using the Impact of Weight on ... Full text Link to item Cite

Usefulness of standard BMI cut-offs for quality of life and psychological well-being in women.

Journal Article Obes Facts · 2012 OBJECTIVE: We examined BMI-based obesity categories and risk for poor health-related quality of life (HRQOL) and psychological well-being (PWB). METHODS: Participants were 1,795 women aged 35.3 ± 10.2 years with a mean BMI of 26.6 kg/m(2), not seeking trea ... Full text Link to item Cite

Six-year changes in health-related quality of life in gastric bypass patients versus obese comparison groups.

Journal Article Surg Obes Relat Dis · 2012 BACKGROUND: Few studies have evaluated the long-term outcomes of bariatric surgery patients in relation to obese individuals not participating in weight loss interventions. Our objective was to evaluate the 6-year changes in health-related quality of life ... Full text Link to item Cite

Improvement in quality of life after laparoscopic sleeve gastrectomy.

Journal Article Obes Surg · August 2011 Few studies have investigated changes in health-related quality of life (HRQOL) in surgical patients who have undergone a laparoscopic sleeve gastrectomy. Prospective data were obtained from 78 consecutive patients undergoing laparoscopic sleeve gastrectom ... Full text Link to item Cite

Health-related quality of life in adolescents with comorbidities related to obesity.

Journal Article J Adolesc Health · July 2011 INTRODUCTION: Psychosocial correlates of medically complex obesity are poorly understood in adolescents. METHODS: Health-related quality of life was examined among 111 obese adolescents with medical comorbidities. RESULTS AND CONCLUSION: A higher body mass ... Full text Link to item Cite

Sleep apnea, reproductive hormones and quality of sexual life in severely obese men.

Journal Article Obesity (Silver Spring) · June 2011 The effect of sleep apnea on the reproductive function of obese men is not entirely elucidated. The objective of this study was to define the effect of sleep apnea on the reproductive hormones and sexual function in obese men. This study included 89 severe ... Full text Link to item Cite

Cardiorespiratory fitness and health-related quality of life in bariatric surgery patients.

Journal Article Obes Surg · April 2011 Health-related quality of life (HRQOL) is impaired in severely obese individuals presenting for bariatric surgery. Little is known about the relationship between cardiorespiratory fitness (CRF) and HRQOL in these individuals. We hypothesized that better HR ... Full text Link to item Cite

Psychometric evaluation of the German version of the impact of weight on Quality of Life-Lite (IWQOL-Lite) questionnaire.

Journal Article Exp Clin Endocrinol Diabetes · February 2011 OBJECTIVE: To evaluate the psychometric properties of a German version of the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire. METHOD: IWQOL-Lite scores were obtained from 351 overweight/obese individuals and 127 lean adult volunteers. ... Full text Link to item Cite

Predicting sleep apnea in bariatric surgery patients.

Journal Article Surg Obes Relat Dis · 2011 BACKGROUND: Because of the high prevalence and potentially serious complications of obstructive sleep apnea (OSA) in obese individuals, several prediction models have been developed to detect moderate-to-severe OSA in patients undergoing bariatric surgery. ... Full text Link to item Cite

Sexual functioning in obese adults enrolling in a weight loss study.

Journal Article J Sex Marital Ther · 2011 The authors assessed sexual functioning among treatment-seeking obese men (n = 91) and women (n = 134) using the comprehensive validated Sexual Functioning Questionnaire. Scores were lower for women than for men, indicating reduced sexual functioning. Men' ... Full text Link to item Cite

Patient-reported outcomes in patients with type 2 diabetes treated with liraglutide or glimepiride, both as add-on to metformin.

Journal Article Prim Care Diabetes · July 2010 Patient-reported outcomes for liraglutide or glimepiride on metformin were investigated. Patients' treatment satisfaction on liraglutide was higher than with metformin alone and comparable with glimepiride+metformin. Patients perceived lower frequency of h ... Full text Link to item Cite

Does pain predict interference with daily functioning and weight loss in an obese residential treatment-seeking population?

Journal Article Int J Behav Med · June 2010 BACKGROUND: Pain may interfere with daily functioning in obese persons and also with outcomes during weight loss. We examined the relationship between pain and (1) interference with daily functioning (DFi) and (2) outcomes in an obese treatment-seeking pop ... Full text Link to item Cite

Effects of aquajogging in obese adults: A pilot study

Journal Article Journal of Obesity · January 1, 2010 Aim and Method. To examine in obese people the potential effectiveness of a six-week, two times weekly aquajogging program on body composition, fitness, health-related quality of life, and exercise beliefs. Fifteen otherwise healthy obese persons participa ... Full text Cite

Psychometric evaluation of a Brazilian version of the impact of weight on quality of life (IWQOL-Lite) instrument.

Journal Article Eur Eat Disord Rev · January 2010 PURPOSE: The impact of weight on quality of life (IWQOL-Lite) is a self-administered instrument that assesses quality of life in obesity. It is composed of 31 items and five domains (physical function, self-esteem, sexual life, public distress, and work). ... Full text Link to item Cite

Body-weight-related quality of life in adolescents: Psychometric quality of the Dutch translation of the verse IWQOL-Kids

Journal Article Tijdschrift voor Kindergeneeskunde · January 1, 2010 Aim: To evaluate the psychometric qualities of the Dutch translation of the Impact of Weight on Quality of Life-Kids (IWQOL-Kids), a measure of body-weight-related quality of life in adolescents (age 11-19 years). Method. The IWQOL-Kids was completed by 10 ... Full text Cite

Health-related quality of life does not vary among patients seeking different surgical procedures to assist with weight loss.

Journal Article Surg Obes Relat Dis · 2010 BACKGROUND: Improvement in quality of life (QOL) is 1 of the goals of bariatric procedures. We hypothesized that greater impairment of QOL would encourage the choice of more invasive surgical procedures. Our study was performed at a university hospital wei ... Full text Link to item Cite

Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obese.

Journal Article Obesity (Silver Spring) · January 2010 Favorable health outcomes at 2 years postbariatric surgery have been reported. With exception of the Swedish Obesity Subjects (SOS) study, these studies have been surgical case series, comparison of surgery types, or surgery patients compared to subjects e ... Full text Link to item Cite

The effect of age on weight-related quality of life in overweight and obese individuals.

Journal Article Obesity (Silver Spring) · July 2009 The objective of the current study was to investigate the association between age and weight-related quality of life in a broad range of overweight/obese individuals. Participants included 9,991 overweight and obese adults from a cross sectional database ( ... Full text Link to item Cite

One-year health-related quality of life outcomes in weight loss trial participants: comparison of three measures.

Journal Article Health Qual Life Outcomes · June 9, 2009 BACKGROUND: The literature on changes in health-related quality of life (HRQOL) in weight loss studies is inconsistent, and few studies use more than one type of measure. The purpose of the current study was to compare one-year changes in HRQOL as a functi ... Full text Link to item Cite

Effect of Roux-en-Y gastric bypass surgery on the sex steroids and quality of life in obese men.

Journal Article J Clin Endocrinol Metab · April 2009 CONTEXT: The effect of bariatric surgery on the reproductive function of obese men is not entirely elucidated. OBJECTIVE: The aim of the study was to define the effect of Roux-En-Y gastric bypass surgery on the reproductive hormones and sexual function in ... Full text Link to item Cite

Effects of two weight-loss diets on health-related quality of life.

Journal Article Qual Life Res · April 2009 PURPOSE: To compare the effects of two diets on health-related quality of life (HRQOL). METHODS: Overweight volunteers (n = 119) were randomized to follow a low-carbohydrate, ketogenic diet (LCKD) or a low-fat diet (LFD) for 24 weeks. HRQOL was measured ev ... Full text Link to item Cite

Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls.

Journal Article Surg Obes Relat Dis · 2009 BACKGROUND: Few weight loss surgery trials have evaluated the changes in health-related quality of life (HRQOL) relative to obese individuals not participating in weight loss interventions. In a prospective study at a bariatric surgery practice, we evaluat ... Full text Link to item Cite

Psychosocial outcomes in a weight loss camp for overweight youth.

Journal Article Int J Pediatr Obes · 2009 OBJECTIVE: There is good evidence that youth attending weight loss camps in the UK and US are successful at achieving weight loss. Limited research suggests improvement in body image and self-esteem as well. This study evaluated changes in eight psychosoci ... Full text Link to item Cite

Changes in weight and weight-related quality of life in a multicentre, randomized trial of aripiprazole versus standard of care.

Journal Article Eur Psychiatry · December 2008 BACKGROUND: This is a secondary analysis of clinical trial data collected in 12 European countries. We examined changes in weight and weight-related quality of life among community patients with schizophrenia treated with aripiprazole (ARI) versus standard ... Full text Link to item Cite

Health-related quality of life before and after bariatric surgery in adolescents.

Journal Article J Pediatr Surg · July 2008 BACKGROUND: Recent data reaffirm decreased health-related quality of life (HRQL) in obese adults and children. Health-related quality of life is markedly improved after bariatric surgery in adults. Little HRQL data are available in adolescents undergoing b ... Full text Link to item Cite

Impact of obesity on health-related quality of life in schizophrenia and bipolar disorder.

Journal Article Obesity (Silver Spring) · April 2008 OBJECTIVE: Studies have reported that up to 60% of individuals with schizophrenia and 68% of those with bipolar disorder are overweight/obese. This paper explores the health-related quality of life (HRQOL) of individuals with schizophrenia or bipolar disor ... Full text Link to item Cite

Health and health-related quality of life: differences between men and women who seek gastric bypass surgery.

Journal Article Surg Obes Relat Dis · 2008 BACKGROUND: The aim of this study was to examine the differences between male and female bariatric surgery candidates with respect to health-related quality of life (HRQOL), health, sociodemographic variables, and interactions among these variables in a ba ... Full text Link to item Cite

Improvements in sexual quality of life after moderate weight loss.

Journal Article Int J Impot Res · 2008 We evaluated changes in sexual quality of life as they relate to weight loss over a 2-year period in individuals undergoing weight loss treatment. Six dimensions of sexual quality of life were measured using items from the Impact of Weight on Quality of Li ... Full text Link to item Cite

Performance of a weight-related measure of Quality of Life in a psychiatric sample.

Journal Article Qual Life Res · May 2006 The Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire has been validated previously in weight loss program participants and community volunteers. Because of the prevalence of obesity in individuals with schizophrenia and bipolar disorder, ... Full text Link to item Cite

Obesity and sexual quality of life.

Journal Article Obesity (Silver Spring) · March 2006 OBJECTIVES: Reduced sexual quality of life is a frequently reported yet rarely studied consequence of obesity. The objectives of this study were to 1) examine the prevalence of sexual quality-of-life difficulties in obese individuals and 2) investigate the ... Full text Link to item Cite

Assessing weight-related quality of life in adolescents.

Journal Article Obesity (Silver Spring) · March 2006 OBJECTIVE: The development of a new weight-related measure to assess quality of life in adolescents [Impact of Weight on Quality of Life (IWQOL)-Kids] is described. RESEARCH METHODS AND PROCEDURES: Using a literature search, clinical experience, and consul ... Full text Link to item Cite

Randomized, double-blind, placebo-controlled trial of orlistat for weight loss in adolescents.

Journal Article Endocr Pract · 2006 OBJECTIVE: To evaluate the efficacy of orlistat to enhance weight loss in obese adolescents. METHODS: The study was a 6-month randomized, double-blind, placebo-controlled trial to compare the effects of orlistat (120 mg orally 3 times a day) and placebo on ... Full text Link to item Cite

Development and psychometric validation of an eating disorder-specific health-related quality of life instrument.

Journal Article Int J Eat Disord · January 2006 OBJECTIVE: Health-related quality of life (HRQOL) has been used increasingly as an outcome measure in clinical research. Although the generic quality of life instruments has been used in previous research, disease-specific instruments offer greater sensiti ... Full text Link to item Cite

Health-related quality of life in overweight and nonoverweight black and white adolescents.

Journal Article J Pediatr · October 2005 OBJECTIVES: To assess the impact of obesity on quality of life (QOL) in black and white adolescents. STUDY DESIGN: One hundred ten overweight (body mass index [BMI], 41.7 +/- 8.9 kg/m2) and 34 nonoverweight adolescents (BMI, 20.6 +/- 2.9 kg/m2) and their p ... Full text Link to item Cite

Design and rationale of the Utah obesity study. A study to assess morbidity following gastric bypass surgery.

Journal Article Contemp Clin Trials · October 2005 PURPOSE: This paper details the design and baseline characteristics of a study on the morbidity associated with Roux-en-Y gastric bypass surgery (GBP) in severely obese adults. This study is designed to assess the effectiveness of GBP in reducing morbidity ... Full text Link to item Cite

Psychometric and cross-national evaluation of a Portuguese version of the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire

Journal Article European Eating Disorders Review · March 1, 2005 Objective: To evaluate the properties of a Portuguese version of the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire and to compare quality of life scores between samples of Portuguese and American women. Research methods and procedures ... Full text Cite

An integrated method to determine meaningful changes in health-related quality of life.

Journal Article J Clin Epidemiol · November 2004 OBJECTIVE: We describe an integrated method for determining meaningful change in health-related quality of life (HRQOL) that combines information from anchor-based and distribution-based methods and illustrate this method using data aggregated from weight ... Full text Link to item Cite

Gender, race, and obesity-related quality of life at extreme levels of obesity.

Journal Article Obes Res · June 2004 OBJECTIVE: Research investigating obesity-related quality of life (QOL) has shown that at increasing levels of overweight, individuals report more impaired QOL. Further, some research has indicated that white women suffer more impairment than men and Afric ... Full text Link to item Cite

Does binge eating disorder impact weight-related quality of life?

Journal Article Obes Res · June 2004 OBJECTIVES: To determine whether binge eating disorder (BED) impacts weight-related quality of life in obese individuals seeking weight loss treatment and to investigate the role of psychological symptoms, BMI, and demographic variables in the relationship ... Full text Link to item Cite

Binge eating, quality of life and physical activity improve after Roux-en-Y gastric bypass for morbid obesity.

Journal Article Obes Surg · March 2004 BACKGROUND: Severe obesity has been associated with disordered eating, impaired quality of life (QoL), and decreased physical activity. This study examines changes in these variables 6 months after Roux-en-Y gastric bypass (RYGBP). METHODS: 40 morbidly obe ... Full text Link to item Cite

Estimating a preference-based single index for the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) instrument from the SF-6D.

Journal Article Value Health · 2004 OBJECTIVE: To facilitate economic evaluations of interventions for treating obesity, we estimated a preference-based single index for the Impact of Weight on Quality of Life-Lite (IWQOL-lite) instrument by mapping it onto the SF-6D preference-based index. ... Full text Link to item Cite

Impact of weight loss and regain on quality of life: mirror image or differential effect?

Journal Article Obes Res · October 2003 OBJECTIVE: To compare the impact of weight regain and weight loss on health-related quality of life. RESEARCH METHODS AND PROCEDURES: Subjects were 122 (106 women, 16 men) overweight and obese participants in a weight reduction program (phentermine-fenflur ... Full text Link to item Cite

The relationship between eating behaviors and obesity in African American and Caucasian women

Journal Article Eating Behaviors · August 1, 2003 The primary goal of this study was to determine the relevance of four self-reported eating behaviors (eating before bedtime, eating between meals, feeling hungry within 3 h of eating, and eating beyond satiation) as risk factors for overweight and obesity. ... Full text Cite

Assessing weight-related quality of life in obese persons with type 2 diabetes.

Journal Article Diabetes Res Clin Pract · August 2003 Because approximately 80% of individuals with type 2 diabetes are obese, we examined weight-related QOL in obese persons with diabetes using the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire. Study participants were enrolled in a clin ... Full text Link to item Cite

Health-related quality of life in patients seeking gastric bypass surgery vs non-treatment-seeking controls.

Journal Article Obes Surg · June 2003 BACKGROUND: Previous research has found that health-related quality of life (HRQOL) differs among obese individuals depending on treatment-seeking status, with greater impairments found in obese individuals seeking treatments of greatest intensity. The goa ... Full text Link to item Cite

Defining clinically meaningful change in health-related quality of life.

Journal Article J Clin Epidemiol · May 2003 This article reviews current approaches to defining clinically meaningful change in health-related quality of life (HRQOL) and provides guidelines for their use. Definitions of clinically meaningful change are discussed. Two broad methods for identifying c ... Full text Link to item Cite

Weight loss with self-help compared with a structured commercial program: a randomized trial.

Journal Article JAMA · April 9, 2003 CONTEXT: Although commercial weight loss programs provide treatment to millions of clients, their efficacy has not been evaluated in rigorous long-term trials. OBJECTIVE: To compare weight loss and health benefits achieved and maintained through self-help ... Full text Link to item Cite

Two measures of health-related quality of life in morbid obesity.

Journal Article Obes Res · November 2002 OBJECTIVE: To compare health-related quality of life (HRQOL) measures in obese presurgery patients with and without binge-eating disorder (BED) and to investigate the relationship between a generic [short form-36 (SF-36)] and a disease-specific HRQOL measu ... Full text Link to item Cite

Health-related quality of life varies among obese subgroups.

Journal Article Obes Res · August 2002 OBJECTIVE: To compare the health-related quality of life (HRQOL) of overweight/obese individuals from different subgroups that vary in treatment-seeking status and treatment intensity. RESEARCH METHODS AND PROCEDURES: Participants were from five distinct g ... Full text Link to item Cite

Psychometric evaluation of the impact of weight on quality of life-lite questionnaire (IWQOL-lite) in a community sample.

Journal Article Qual Life Res · March 2002 The short form of impact of weight on quality of life (IWQOL)-Lite is a 31-item, self-report, obesity-specific measure of health-related quality of life (HRQOL) that consists of a total score and scores on each of five scales--physical function, self-estee ... Full text Link to item Cite

Quality of life and obesity.

Journal Article Obes Rev · November 2001 Interest in the quality of life of patients with different diseases continues to grow. Recent years have witnessed a dramatic rise in the prevalence of obesity worldwide, stimulating interest in the health and quality of life consequences of this phenomeno ... Full text Link to item Cite

The relationship between health-related quality of life and weight loss.

Journal Article Obes Res · September 2001 OBJECTIVE: This is a report of health-related quality of life (HRQOL) changes in obese patients completing at least 1 year of outpatient treatment in a weight reduction program combining phentermine-fenfluramine and dietary counseling. RESEARCH METHODS AND ... Full text Link to item Cite

Effect of moderate weight loss on health-related quality of life: an analysis of combined data from 4 randomized trials of sibutramine vs placebo.

Journal Article Am J Manag Care · September 2001 OBJECTIVES: To determine whether (1) patients who experience greater weight loss also experience correspondingly greater improvements in health-related quality of life (HRQOL); (2) the improvement in HRQOL is noticeable for patients achieving moderate (5%- ... Link to item Cite

Development of a brief measure to assess quality of life in obesity.

Journal Article Obes Res · February 2001 OBJECTIVE: Obesity researchers have a growing interest in measuring the impact of weight and weight reduction on quality of life. The Impact of Weight on Quality of Life questionnaire (IWQOL) was the first self-report instrument specifically developed to a ... Full text Link to item Cite

Construct validity of the Impact of Weight on Quality of Life Questionnaire.

Journal Article Obes Res · September 1997 The Impact of Weight on Quality of Life questionnaire (IWQOL) is a 74-item self-report, condition-specific instrument that (1) assesses the effect of weight on quality of life in eight key areas, and (2) may be used as a treatment outcome measure and/or an ... Full text Link to item Cite

Quality-of-life Improvements may Enhance Effects of Modest Weight Loss

Journal Article Journal of the American Dietetic Association · May 1, 1995 Full text Cite

Assessing Impact of Weight on Quality of Life.

Journal Article Obes Res · January 1995 This paper is a preliminary report on the development of a new instrument, the Impact of Weight on Quality of Life (IWQOL) questionnaire, that assesses the effects of weight on various areas of life. We conducted two studies utilizing subjects in treatment ... Full text Link to item Cite

A comparison of binge‐purgers, obese binge eaters, and obese nonbinge eaters on the MMPI

Journal Article International Journal of Eating Disorders · January 1, 1992 This study compared the (MMPI) score distributions obtained by binge‐purgers (n = 34), obese binge eaters (n = 341), and obese nonbingers (n = 34) of similar age. Significant differences emerged among the three groups on all MMPI scales except Masculinity‐ ... Full text Cite

Binge eating in obesity: associated MMPI characteristics.

Journal Article J Consult Clin Psychol · December 1987 Full text Link to item Cite

Attrition in a behavioral weight‐control program: A comparison of dropouts and completers

Journal Article International Journal of Eating Disorders · January 1, 1983 A major problem in weight‐reduction programs is that a significant number of individuals terminate treatment prematurely. To help alleviate some of the problems associated with high attrition, it is important to understand the ways in which treatment dropo ... Full text Cite

Computers in biofeedback research and therapy

Journal Article Behavior Research Methods & Instrumentation · July 1, 1981 While biofeedback is being used extensively in the clinic and the laboratory, a great deal of variability exists among biofeedback users with respect to instrumentation, treatment protocols, techniques of data acquisition, and methods of data analysis. It ... Full text Cite

Evaluation of outcome in brief psychotherapy

Journal Article Psychiatric Clinics of North America · January 1, 1979 Brief psychotherapy, once considered a stopgap or emergency treatment measure, has now become a major treatment of choice. Most psychotherapeutic interventions are in fact brief, whether or not they were intended to be at the beginning of therapy. Brief ps ... Full text Cite

Effects of Computerized Administration on Scores on the Minnesota Multiphasic Personality Inventory

Journal Article Applied Psychological Measurement · January 1, 1977 This study investigated the effects of administer ing a personality inventory by computer. Both the results of the initial study and a replication suggest that significant differences exist between paper-pen cil and computer administrations of the MMPI on ... Full text Cite