Jed Eugene Rose
Professor Emeritus in Psychiatry and Behavioral Sciences
We are pursuing three main lines of research:
1) Brain imaging of the effects of nicotine and cigarette smoking: We have used Positron Emission Tomography (PET) methods to analyze regional cerebral blood flow responses to nicotine, administered either intravenously or inhaled in cigarettes. Our aim is to identify brain substrates mediating the addictive properties of nicotine. Preliminary results have shown alterations in the pattern of regional cerebral blood flow, involving frontal cortex, amygdala and other brain regions. We will continue to delineate the similarities and differences between the effects of nicotine and other drugs on regional brain activity, and plan to monitor the changes in response to nicotine after smoking cessation with nicotine antagonist treatment.
2) Analysis of airway sensory components of smoking reinforcement: We have continued the study the role of sensorimotor aspects of cigarette smoking in relieving craving for cigarettes and regulating smoke intake. We completed a study of the effects of intravenous nicotine presented alone or in combination with the sensorimotor aspects of smoking using de-nicotinized cigarette smoke. Craving for cigarettes was relieved more effectively by the de-nicotinized smoke than by the intravenous nicotine. Current studies underway at the Clinical Research Unit will further investigate the subjective effects of i.v. nicotine and de-nicotinized cigarette smoke, using a wider range of nicotine doses. Possible predictors of clinical outcome following nicotine skin patch treatment will be identified based on acute responses to the pharmacologic effects of nicotine in the laboratory.
We are also continuing to further the clinical application of these findings by developing substitutes that provide the airways sensory effects of smoking (e.g. citric acid aerosol).
3) Agonist/antagonist combination treatment for drug dependence: In a double blind smoking cessation trial using mecamylamine, a nicotinic antagonist, in combination with nicotine skin patches, we found that addition of the antagonist substantially increases smoking abstinence throughout the 1 year follow-up. Two additional studies that we conducted support the view that pre-treatment with mecamylamine prior to smoking cessation may be a critical factor in achieving high success rates. By blocking reinforcing effects of nicotine, smoking behavior may be partially extinguished, thereby facilitating subsequent smoking cessation. We recently completed a Phase II FDA trial evaluating a transdermal patch delivering nicotine and mecamylamine, which replicated our previous results. It is anticipated that an NDA pertaining to the new skin patch will be submitted in 1997. Continuing studies in our program will determine the optimal dose and duration of treatment. We also have initiated studies to extend this approach to the treatment of other drug dependencies, including cocaine.
1) Brain imaging of the effects of nicotine and cigarette smoking: We have used Positron Emission Tomography (PET) methods to analyze regional cerebral blood flow responses to nicotine, administered either intravenously or inhaled in cigarettes. Our aim is to identify brain substrates mediating the addictive properties of nicotine. Preliminary results have shown alterations in the pattern of regional cerebral blood flow, involving frontal cortex, amygdala and other brain regions. We will continue to delineate the similarities and differences between the effects of nicotine and other drugs on regional brain activity, and plan to monitor the changes in response to nicotine after smoking cessation with nicotine antagonist treatment.
2) Analysis of airway sensory components of smoking reinforcement: We have continued the study the role of sensorimotor aspects of cigarette smoking in relieving craving for cigarettes and regulating smoke intake. We completed a study of the effects of intravenous nicotine presented alone or in combination with the sensorimotor aspects of smoking using de-nicotinized cigarette smoke. Craving for cigarettes was relieved more effectively by the de-nicotinized smoke than by the intravenous nicotine. Current studies underway at the Clinical Research Unit will further investigate the subjective effects of i.v. nicotine and de-nicotinized cigarette smoke, using a wider range of nicotine doses. Possible predictors of clinical outcome following nicotine skin patch treatment will be identified based on acute responses to the pharmacologic effects of nicotine in the laboratory.
We are also continuing to further the clinical application of these findings by developing substitutes that provide the airways sensory effects of smoking (e.g. citric acid aerosol).
3) Agonist/antagonist combination treatment for drug dependence: In a double blind smoking cessation trial using mecamylamine, a nicotinic antagonist, in combination with nicotine skin patches, we found that addition of the antagonist substantially increases smoking abstinence throughout the 1 year follow-up. Two additional studies that we conducted support the view that pre-treatment with mecamylamine prior to smoking cessation may be a critical factor in achieving high success rates. By blocking reinforcing effects of nicotine, smoking behavior may be partially extinguished, thereby facilitating subsequent smoking cessation. We recently completed a Phase II FDA trial evaluating a transdermal patch delivering nicotine and mecamylamine, which replicated our previous results. It is anticipated that an NDA pertaining to the new skin patch will be submitted in 1997. Continuing studies in our program will determine the optimal dose and duration of treatment. We also have initiated studies to extend this approach to the treatment of other drug dependencies, including cocaine.
Current Appointments & Affiliations
- Professor Emeritus in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2022
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1989
Contact Information
- 2424 Erwin Road, Suite 201, Durham, NC 27705
- Box 2701 Med Ctr, Durham, NC 27710
-
rose0003@mc.duke.edu
(919) 668-5055
- Background
-
Education, Training, & Certifications
- Ph.D., University of California - San Diego 1978
-
Previous Appointments & Affiliations
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2021 - 2022
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2006 - 2020
- Research Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1998 - 2006
- Associate Research Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1994 - 1998
- Recognition
-
In the News
-
OCT 15, 2019 Duke Research Blog -
APR 12, 2016 The Wall Street Journal -
APR 12, 2016 The Wall Street Journal -
FEB 5, 2016 The New York Times -
FEB 5, 2016 The New York Times -
APR 17, 2015 CBC News, Reuters -
APR 17, 2015 CBC News -
JUN 18, 2014 Toronto Sun -
JUN 17, 2014 Duke Today -
JUN 17, 2014 -
MAY 8, 2014 WRAL -
MAY 8, 2014 WRAL -
OCT 14, 2013 Durham Herald-Sun -
OCT 14, 2013 Durham Herald-Sun -
MAR 27, 2013
-
- Research
-
Selected Grants
- E-cigarettes: deposition, absorption and brain accumulation of nicotine awarded by National Institutes of Health 2017 - 2023
- The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence awarded by National Institutes of Health 2015 - 2021
- Population-Based Sero-Epidemiological Investigation Protocol for the Impact of Smoking on SARS-COV-2 Infection and COVID-19 Outcomes: The Troina Study awarded by ECLAT 2020 - 2021
- Center for Adaptive Treatment of Cigarette Addiction awarded by National Institutes of Health 2010 - 2021
- Neural Circuitry Involved in Pulmonary Nicotine Sensation during Smoking awarded by Altria Client Services LLC 2019 - 2020
- Alpha 5 Nicotinic Receptor Subunit Gene Polymorphisms and Smoking Addiction awarded by National Institutes of Health 2013 - 2019
- Novel Approach to Quantify Nicotinic Receptor Upregulation in Smokers awarded by National Institutes of Health 2014 - 2017
- P50 Supplement awarded by National Institutes of Health 2010 - 2015
- Neural Substrates of Extinction-Based Treatment for Nicotine Dependence awarded by National Institutes of Health 2008 - 2014
- Optimal Smoking Cessation Treatment in PTSD awarded by National Institutes of Health 2003 - 2014
- Effects of Cigarette Mentholation on Brain Nicotine Accumulation During Smoking awarded by National Institutes of Health 2011 - 2013
- Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction awarded by National Institutes of Health 2008 - 2013
- Improving the efficacy of anti-nicotine immunotherapy awarded by National Institutes of Health 2009 - 2012
- Smoking & Anxiety In Posttraumatic Stress Disorder awarded by National Institutes of Health 1998 - 2012
- Stress and Behavior in Health and Disease awarded by National Institutes of Health 1989 - 2011
- Neuroimaging Attentional Impairment During Abstinence awarded by National Institutes of Health 2004 - 2009
- The Effect of Smoking on Startle & PPI in PTSD awarded by National Institutes of Health 2006 - 2009
- Oral nicotine replacement for Smoking Cessation awarded by National Institutes of Health 2003 - 2006
- Drug Cue Reactivity in Smokers: An fMRI Investigation awarded by National Institutes of Health 2002 - 2004
- Scaling The Reinforcing Value Of Cigarette Smoke awarded by National Institutes of Health 1999 - 2004
- Same awarded by National Institutes of Health 1996 - 2002
- Dopaminergic Mechanisms Of Nicotine Addiction awarded by National Institutes of Health 1997 - 2002
- Same awarded by National Institutes of Health 1996 - 2000
- Nicotinic Influences On Alcohol Use And Dependence awarded by National Institutes of Health 1996 - 1999
- Nicotine Tolerance And Blockade In Cigarette Smokers awarded by National Institutes of Health 1996 - 1999
- Dopaminergic Mechanisms In Nicotine Addiction awarded by National Institutes of Health 1997 - 1999
- Phentermine And Fenfluramine For Smoking Cestation awarded by National Institutes of Health 1997 - 1999
- Neuroanatomical Substrates Of Nicotine Addiction awarded by National Institutes of Health 1995 - 1998
- Caffine Effects On Stress Reactivy awarded by National Institutes of Health 1995 - 1998
- Drive To Smoke And Dopamine Blockade awarded by National Institutes of Health 1994 - 1997
- Neuroanatomiacal Substrates Of Nicotine Addiction awarded by National Institutes of Health 1995 - 1997
- Biobehavioral Factors In Coronary Heart Disease awarded by National Institutes of Health 1994 - 1996
- Biobehaviorial Factors In Coronary Heart Disease awarded by National Institutes of Health 1993 - 1996
- Caffine'S Effects On Smoking And Nicotine Withdrawal awarded by National Institutes of Health 1993 - 1995
- Scaling The Reinforcing Value Of Cigarette Smoke awarded by National Institutes of Health 1993 - 1994
-
External Relationships
- Altria Group Inc
- Embera Neurotherapeutics
- Foundation for a Smoke Free World
- JUUL Labs, Inc.
- Philip Morris International
- Revive Pharmaceuticals
- Rose Research Center LLC
- Sentiens, LLC
- Publications & Artistic Works
-
Selected Publications
-
Academic Articles
-
Rose, Jed E., Frederique M. Behm, Tanaia L. Botts, David R. Botts, Perry N. Willette, Frank Vocci, and John McCarty. “Novel rapid-acting sublingual nicotine tablet as a cigarette substitution strategy.” Psychopharmacology (Berl) 239, no. 9 (September 2022): 2853–62. https://doi.org/10.1007/s00213-022-06171-z.Full Text Link to Item
-
Tomaselli, Venera, Pietro Ferrara, Giulio G. Cantone, Alba C. Romeo, Sonja Rust, Daniela Saitta, Filippo Caraci, et al. “The effect of laboratory-verified smoking on SARS-CoV-2 infection: results from the Troina sero-epidemiological survey.” Intern Emerg Med 17, no. 6 (September 2022): 1617–30. https://doi.org/10.1007/s11739-022-02975-1.Full Text Link to Item
-
Rose, Jed E., Perry N. Willette, Tanaia L. Botts, David R. Botts, and Frederique M. Behm. “Bupropion/zonisamide combination to assist smokers to switch from combustible cigarettes to electronic nicotine delivery systems (ENDS).” Drug Alcohol Depend 234 (May 1, 2022): 109346. https://doi.org/10.1016/j.drugalcdep.2022.109346.Full Text Link to Item
-
Levin, Edward D., Corinne Wells, Susan Slade, Joshua Johnson, Ann Petro, Amir H. Rezvani, and Jed E. Rose. “Chronic infusions of mecamylamine into the medial habenula: Effects on nicotine self-administration in rats.” Behav Brain Res 416 (January 7, 2022): 113574. https://doi.org/10.1016/j.bbr.2021.113574.Full Text Link to Item
-
Levin, Edward D., Corinne Wells, Caroline Pace, Grant Abass, Andrew Hawkey, Zade Holloway, Amir H. Rezvani, and Jed E. Rose. “Self-administration by female rats of low doses of nicotine alone vs. nicotine in tobacco smoke extract.” Drug Alcohol Depend 228 (November 1, 2021): 109073. https://doi.org/10.1016/j.drugalcdep.2021.109073.Full Text Link to Item
-
Polosa, R., V. Tomaselli, P. Ferrara, A. C. Romeo, S. Rust, D. Saitta, F. Caraci, et al. “Seroepidemiological survey on the impact of smoking on SARS-CoV-2 infection and COVID-19 outcomes: Protocol for the troina study.” Jmir Research Protocols 10, no. 11 (November 1, 2021). https://doi.org/10.2196/32285.Full Text
-
Salzberger, T., S. Cano, L. Abetz-Webb, E. Afolalu, C. Chrea, R. Weitkunat, and J. Rose. “Addressing traceability of self-reported dependence measurement through the use of crosswalks.” Measurement: Journal of the International Measurement Confederation 181 (August 1, 2021). https://doi.org/10.1016/j.measurement.2021.109593.Full Text
-
Levin, Edward D., Corinne Wells, Andrew Hawkey, Zade Holloway, Graham Blair, Alexander Vierling, Ashley Ko, et al. “Correction to: Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.” Psychopharmacology (Berl) 238, no. 4 (April 2021): 1227. https://doi.org/10.1007/s00213-021-05794-y.Full Text Link to Item
-
Patwardhan, S., and J. E. Rose. “Overcoming barriers to disseminate effective smoking cessation treatments globally.” Drugs and Alcohol Today 20, no. 3 (September 10, 2020): 235–47. https://doi.org/10.1108/DAT-01-2020-0001.Full Text
-
Rose, Jed E., and James M. Davis. “Combination Lorcaserin and Nicotine Patch for Smoking Cessation Without Weight Gain.” Nicotine Tob Res 22, no. 9 (August 24, 2020): 1627–31. https://doi.org/10.1093/ntr/ntz149.Full Text Open Access Copy Link to Item
-
Solingapuram Sai, Kiran Kumar, Yantao Zuo, Jed E. Rose, Pradeep K. Garg, Sudha Garg, Rachid Nazih, Akiva Mintz, and Alexey G. Mukhin. “Rapid Brain Nicotine Uptake from Electronic Cigarettes.” J Nucl Med 61, no. 6 (June 2020): 928–30. https://doi.org/10.2967/jnumed.119.230748.Full Text Link to Item
-
Blair, Graham, Corinne Wells, Ashley Ko, John Modarres, Caroline Pace, James M. Davis, Amir H. Rezvani, Jed E. Rose, and Edward D. Levin. “Dextromethorphan and bupropion reduces high level remifentanil self-administration in rats.” Pharmacol Biochem Behav 193 (June 2020): 172919. https://doi.org/10.1016/j.pbb.2020.172919.Full Text Open Access Copy Link to Item
-
Levin, Edward D., Corinne Wells, Andrew Hawkey, Zade Holloway, Graham Blair, Alexander Vierling, Ashley Ko, et al. “Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.” Psychopharmacology (Berl) 237, no. 6 (June 2020): 1681–89. https://doi.org/10.1007/s00213-020-05489-w.Full Text Link to Item
-
Levin, Edward D., Corinne Wells, Susan Slade, Michelle Lee, Anthony A. McKinney, Jed E. Rose, and Amir H. Rezvani. “Prolonging the Reduction of Nicotine Self-Administration in Rats by Coadministering Chronic Nicotine With Amitifadine, a Triple Monoamine Reuptake Inhibitor With CYP2B6 Inhibitory Actions.” Nicotine Tob Res 22, no. 2 (February 6, 2020): 232–37. https://doi.org/10.1093/ntr/ntz054.Full Text Open Access Copy Link to Item
-
Levin, Edward D., Corinne Wells, Leah Yao, Wendi Guo, Anica Nangia, Sarah Howard, Erica Pippen, Andrew B. Hawkey, Jed E. Rose, and Amir H. Rezvani. “Chronic memantine decreases nicotine self-administration in rats.” Eur J Pharmacol 861 (October 15, 2019): 172592. https://doi.org/10.1016/j.ejphar.2019.172592.Full Text Link to Item
-
Rose, J. E., P. N. Willette, T. H. Loeback, and D. R. Botts. “Evaluation of a Botanical Extract that Mimics the Respiratory Cues of Cigarette Smoke.” Journal of Smoking Cessation 14, no. 1 (March 1, 2019): 59–64. https://doi.org/10.1017/jsc.2018.14.Full Text
-
Hughes, John R., Karl O. Fagerstrom, Jack E. Henningfield, Brad Rodu, Jed E. Rose, and Saul Shiffman. “Why we work with the tobacco industry.” Addiction 114, no. 2 (February 2019): 374–75. https://doi.org/10.1111/add.14461.Full Text Link to Item
-
Chrea, Christelle, Catherine Acquadro, Esther F. Afolalu, Erica Spies, Thomas Salzberger, Linda Abetz-Webb, Stefan Cano, et al. “Developing fit-for-purpose self-report instruments for assessing consumer responses to tobacco and nicotine products: the ABOUT™ Toolbox initiative.” F1000res 7 (2018): 1878. https://doi.org/10.12688/f1000research.16810.1.Full Text Link to Item
-
Rose, Jed E., and Frédérique M. Behm. “Combination Varenicline/Bupropion Treatment Benefits Highly Dependent Smokers in an Adaptive Smoking Cessation Paradigm.” Nicotine Tob Res 19, no. 8 (August 1, 2017): 999–1002. https://doi.org/10.1093/ntr/ntw283.Full Text Link to Item
-
Shanahan, William R., Jed E. Rose, Alan Glicklich, Scott Stubbe, and Matilde Sanchez-Kam. “Lorcaserin for Smoking Cessation and Associated Weight Gain: A Randomized 12-Week Clinical Trial.” Nicotine Tob Res 19, no. 8 (August 1, 2017): 944–51. https://doi.org/10.1093/ntr/ntw301.Full Text Link to Item
-
Zuo, Yantao, Pradeep K. Garg, Rachid Nazih, Sudha Garg, Jed E. Rose, Thangaraju Murugesan, and Alexey G. Mukhin. “A programmable smoke delivery device for PET imaging with cigarettes containing 11C-nicotine.” J Neurosci Methods 283 (May 1, 2017): 55–61. https://doi.org/10.1016/j.jneumeth.2017.03.016.Full Text Link to Item
-
Levin, Edward D., Brandon J. Hall, Autri Chattopadhyay, Susan Slade, Corinne Wells, Amir H. Rezvani, and Jed E. Rose. “Reduction of nicotine self-administration by chronic nicotine infusion with H1 histamine blockade in female rats.” Psychopharmacology (Berl) 233, no. 15–16 (August 2016): 3009–15. https://doi.org/10.1007/s00213-016-4347-1.Full Text Link to Item
-
McClernon, Francis Joseph, Brett Froeliger, Jed E. Rose, Rachel V. Kozink, Merideth A. Addicott, Maggie M. Sweitzer, Eric C. Westman, and Dana M. Van Wert. “The effects of nicotine and non-nicotine smoking factors on working memory and associated brain function.” Addict Biol 21, no. 4 (July 2016): 954–61. https://doi.org/10.1111/adb.12253.Full Text Link to Item
-
Briggs, Scott A., Brandon J. Hall, Corinne Wells, Susan Slade, Paul Jaskowski, Margaret Morrison, Amir H. Rezvani, Jed E. Rose, and Edward D. Levin. “Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats.” Pharmacol Biochem Behav 142 (March 2016): 1–7. https://doi.org/10.1016/j.pbb.2015.12.004.Full Text Link to Item
-
Rezvani, Amir H., Marty C. Cauley, Susan Slade, Corinne Wells, Stanley Glick, Jed E. Rose, and Edward D. Levin. “Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats.” Pharmacol Biochem Behav 150–151 (2016): 153–57. https://doi.org/10.1016/j.pbb.2016.10.010.Full Text Link to Item
-
Levin, Edward D., Corinne Wells, Joshua E. Johnson, Amir H. Rezvani, Frank P. Bymaster, and Jed E. Rose. “Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats.” Eur J Pharmacol 764 (October 5, 2015): 30–37. https://doi.org/10.1016/j.ejphar.2015.06.041.Full Text Link to Item
-
Addicott, Merideth A., Maggie M. Sweitzer, Brett Froeliger, Jed E. Rose, and Francis J. McClernon. “Increased Functional Connectivity in an Insula-Based Network is Associated with Improved Smoking Cessation Outcomes.” Neuropsychopharmacology 40, no. 11 (October 2015): 2648–56. https://doi.org/10.1038/npp.2015.114.Full Text Link to Item
-
Rose, Jed E., and Frédérique M. Behm. “Response to Gorelick.” Am J Psychiatry 172, no. 4 (April 2015): 395. https://doi.org/10.1176/appi.ajp.2015.14111429r.Full Text Link to Item
-
Zuo, Yantao, Alexey G. Mukhin, Sudha Garg, Rachid Nazih, Frederique M. Behm, Pradeep K. Garg, and Jed E. Rose. “Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior.” Neuropsychopharmacology 40, no. 4 (March 2015): 884–92. https://doi.org/10.1038/npp.2014.263.Full Text Link to Item
-
Hall, Brandon J., Susan Slade, Corinne Wells, Jed E. Rose, and Edward D. Levin. “Bupropion-varenicline interactions and nicotine self-administration behavior in rats.” Pharmacol Biochem Behav 130 (March 2015): 84–89. https://doi.org/10.1016/j.pbb.2015.01.009.Full Text Link to Item
-
Dehkordi, Ozra, Jed E. Rose, Sadegh Asadi, Kebreten F. Manaye, Richard M. Millis, and Annapurni Jayam-Trouth. “Neuroanatomical circuitry mediating the sensory impact of nicotine in the central nervous system.” J Neurosci Res 93, no. 2 (February 2015): 230–43. https://doi.org/10.1002/jnr.23477.Full Text Link to Item
-
Walton, Kevin M., David B. Abrams, William C. Bailey, David Clark, Gregory N. Connolly, Mirjana V. Djordjevic, Thomas E. Eissenberg, et al. “NIH electronic cigarette workshop: developing a research agenda.” Nicotine Tob Res 17, no. 2 (February 2015): 259–69. https://doi.org/10.1093/ntr/ntu214.Full Text Link to Item
-
Addicott, Merideth A., Brett Froeliger, Rachel V. Kozink, Dana M. Van Wert, Eric C. Westman, Jed E. Rose, and Francis J. McClernon. “Nicotine and non-nicotine smoking factors differentially modulate craving, withdrawal and cerebral blood flow as measured with arterial spin labeling.” Neuropsychopharmacology 39, no. 12 (November 2014): 2750–59. https://doi.org/10.1038/npp.2014.108.Full Text Link to Item
-
Rose, Jed E., and Frédérique M. Behm. “Combination treatment with varenicline and bupropion in an adaptive smoking cessation paradigm.” Am J Psychiatry 171, no. 11 (November 1, 2014): 1199–1205. https://doi.org/10.1176/appi.ajp.2014.13050595.Full Text Link to Item
-
Cousins, Vanessa, Jed E. Rose, and Edward D. Levin. “IV nicotine self-administration in rats using a consummatory operant licking response: sensitivity to serotonergic, glutaminergic and histaminergic drugs.” Prog Neuropsychopharmacol Biol Psychiatry 54 (October 3, 2014): 200–205. https://doi.org/10.1016/j.pnpbp.2014.06.004.Full Text Link to Item
-
Brody, Arthur L., Alexey G. Mukhin, Michael S. Mamoun, Trinh Luu, Meaghan Neary, Lidia Liang, Jennifer Shieh, Catherine A. Sugar, Jed E. Rose, and Mark A. Mandelkern. “Brain nicotinic acetylcholine receptor availability and response to smoking cessation treatment: a randomized trial.” Jama Psychiatry 71, no. 7 (July 1, 2014): 797–805. https://doi.org/10.1001/jamapsychiatry.2014.138.Full Text Link to Item
-
Rose, J. E., and F. M. Behm. “Combination Treatment With Varenicline and Bupropion in an Adaptive Smoking Cessation Paradigm.” American Journal of Psychiatry, June 17, 2014. https://doi.org/10.1176/appi.ajp.2014.Full Text Open Access Copy Link to Item
-
Hall, Brandon J., Corinne Wells, Cheyenne Allenby, Mung Yan Lin, Ian Hao, Lindsey Marshall, Jed E. Rose, and Edward D. Levin. “Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats.” Pharmacol Biochem Behav 120 (May 2014): 103–8. https://doi.org/10.1016/j.pbb.2014.02.011.Full Text Link to Item
-
Uhl, G. R., D. Walther, R. Musci, C. Fisher, J. C. Anthony, C. L. Storr, F. M. Behm, W. W. Eaton, N. Ialongo, and J. E. Rose. “Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances.” Molecular Psychiatry 19, no. 1 (January 1, 2014): 50–54. https://doi.org/10.1038/mp.2012.155.Full Text
-
Uhl, G. R., D. Walther, R. Musci, C. Fisher, J. C. Anthony, C. L. Storr, F. M. Behm, W. W. Eaton, N. Ialongo, and J. E. Rose. “Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances.” Mol Psychiatry 19, no. 1 (January 2014): 50–54. https://doi.org/10.1038/mp.2012.155.Full Text Link to Item
-
Kutlu, Munir G., Dennis Burke, Susan Slade, Brandon J. Hall, Jed E. Rose, and Edward D. Levin. “Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats.” Behav Brain Res 256 (November 1, 2013): 273–78. https://doi.org/10.1016/j.bbr.2013.08.005.Full Text Link to Item
-
Thorgeirsson, T. E., D. F. Gudbjartsson, P. Sulem, S. Besenbacher, U. Styrkarsdottir, G. Thorleifsson, G. B. Walters, et al. “A common biological basis of obesity and nicotine addiction.” Transl Psychiatry 3, no. 10 (October 1, 2013): e308. https://doi.org/10.1038/tp.2013.81.Full Text Link to Item
-
Rose, Jed E., and Frédérique M. Behm. “Adapting smoking cessation treatment according to initial response to precessation nicotine patch.” Am J Psychiatry 170, no. 8 (August 2013): 860–67. https://doi.org/10.1176/appi.ajp.2013.12070919.Full Text Link to Item
-
Bough, K. J., C. Lerman, J. E. Rose, F. J. McClernon, P. J. Kenny, R. F. Tyndale, S. P. David, et al. “Biomarkers for smoking cessation.” Clin Pharmacol Ther 93, no. 6 (June 2013): 526–38. https://doi.org/10.1038/clpt.2013.57.Full Text Link to Item
-
Dehkordi, Ozra, Jed E. Rose, Mehrnaz Fatemi, Joanne S. Allard, Kannan V. Balan, John K. Young, Sabiha Fatima, Richard M. Millis, and Annapurni Jayam-Trouth. “Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem.” Brain Res 1475 (September 26, 2012): 1–10. https://doi.org/10.1016/j.brainres.2012.07.038.Full Text Link to Item
-
Rose, Jed E., Ozra Dehkordi, Mehrnaz Fatemi, Ramya Raghupathi, Richard M. Millis, and Annapurni Jayam-Trouth. “Neuroanatomical evidence for a putative autocrine/paracrine signaling system involving nicotinic acetylcholine receptors, purinergic receptors, and nitric oxide synthase in the airways.” J Neurosci Res 90, no. 4 (April 2012): 849–59. https://doi.org/10.1002/jnr.22817.Full Text Link to Item
-
Uhl, George R., Donna Walther, Frederique M. Behm, and Jed E. Rose. “Menthol preference among smokers: association with TRPA1 variants.” Nicotine Tob Res 13, no. 12 (December 2011): 1311–15. https://doi.org/10.1093/ntr/ntr119.Full Text Link to Item
-
Rose, Jed E., F Joseph McClernon, Brett Froeliger, Frédérique M. Behm, Xavier Preud’homme, and Andrew D. Krystal. “Repetitive transcranial magnetic stimulation of the superior frontal gyrus modulates craving for cigarettes.” Biol Psychiatry 70, no. 8 (October 15, 2011): 794–99. https://doi.org/10.1016/j.biopsych.2011.05.031.Full Text Link to Item
-
Rose, Jed E. “Nicotine preloading: the importance of a pre-cessation reduction in smoking behavior.” Psychopharmacology (Berl) 217, no. 3 (October 2011): 453–54. https://doi.org/10.1007/s00213-011-2350-0.Full Text Link to Item
-
Levin, Edward D., Joshua E. Johnson, Susan Slade, Corinne Wells, Marty Cauley, Ann Petro, and Jed E. Rose. “Lorcaserin, a 5-HT2C agonist, decreases nicotine self-administration in female rats.” J Pharmacol Exp Ther 338, no. 3 (September 2011): 890–96. https://doi.org/10.1124/jpet.111.183525.Full Text Link to Item
-
Bevins, Rick, Paul Kenny, and Jed Rose. “Response: a quest and a wager.” Addict Sci Clin Pract 6, no. 1 (July 2011): 16–17.Link to Item
-
Levin, Edward D., Susan Slade, Corinne Wells, Ann Petro, and Jed E. Rose. “D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response.” Pharmacol Biochem Behav 98, no. 2 (April 2011): 210–14. https://doi.org/10.1016/j.pbb.2010.12.023.Full Text Link to Item
-
Uhl, George R., and Jed E. Rose. “Individualized smoking cessation treatment: roles for sets of genomic markers.” Per Med 8, no. 2 (March 2011): 119–21. https://doi.org/10.2217/pme.11.4.Full Text Link to Item
-
Levin, Edward D., Susan Slade, Corinne Wells, Margaret Pruitt, Vanessa Cousins, Marty Cauley, Ann Petro, Dawn Hampton, and Jed Rose. “Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.” Eur J Pharmacol 650, no. 1 (January 10, 2011): 256–60. https://doi.org/10.1016/j.ejphar.2010.10.013.Full Text Link to Item
-
Levin, Edward D., Dawn Hampton, and Jed E. Rose. “IV nicotine self-administration in rats using the consummatory operant licking response.” Physiol Behav 101, no. 5 (December 2, 2010): 755–58. https://doi.org/10.1016/j.physbeh.2010.08.016.Full Text Link to Item
-
Rose, Jed E., Frédérique M. Behm, Thangaraju Murugesan, and F Joseph McClernon. “Silver acetate interactions with nicotine and non-nicotine smoke components.” Exp Clin Psychopharmacol 18, no. 6 (December 2010): 462–69. https://doi.org/10.1037/a0021966.Full Text Link to Item
-
Rose, Jed E. “Stress alleviation and reward enhancement: two promising targets for relapse prevention.” Biol Psychiatry 68, no. 8 (October 15, 2010): 687–88. https://doi.org/10.1016/j.biopsych.2010.08.023.Full Text Link to Item
-
Kozink, Rachel V., Avery M. Lutz, Jed E. Rose, Brett Froeliger, and F Joseph McClernon. “Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition.” Addict Biol 15, no. 4 (October 2010): 480–90. https://doi.org/10.1111/j.1369-1600.2010.00252.x.Full Text Link to Item
-
Rose, Jed E., James E. Turner, Thangaraju Murugesan, Frédérique M. Behm, and Murray Laugesen. “Pulmonary delivery of nicotine pyruvate: sensory and pharmacokinetic characteristics.” Exp Clin Psychopharmacol 18, no. 5 (October 2010): 385–94. https://doi.org/10.1037/a0020834.Full Text Link to Item
-
Rezvani, Amir H., Susan Slade, Cori Wells, Ann Petro, Lawrence Lumeng, Ting-Kai Li, Yingxian Xiao, et al. “Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.” Psychopharmacology (Berl) 211, no. 2 (August 2010): 161–74. https://doi.org/10.1007/s00213-010-1878-8.Full Text Link to Item
-
Froeliger, Brett, Rachel V. Kozink, Jed E. Rose, Frederique M. Behm, Alfred N. Salley, and F Joseph McClernon. “Hippocampal and striatal gray matter volume are associated with a smoking cessation treatment outcome: results of an exploratory voxel-based morphometric analysis.” Psychopharmacology (Berl) 210, no. 4 (July 2010): 577–83. https://doi.org/10.1007/s00213-010-1862-3.Full Text Link to Item
-
Rose, Jed E., Al Salley, Frederique M. Behm, James E. Bates, and Eric C. Westman. “Reinforcing effects of nicotine and non-nicotine components of cigarette smoke.” Psychopharmacology (Berl) 210, no. 1 (May 2010): 1–12. https://doi.org/10.1007/s00213-010-1810-2.Full Text Link to Item
-
Tobacco and Genetics Consortium, Mark. “Genome-wide meta-analyses identify multiple loci associated with smoking behavior.” Nat Genet 42, no. 5 (May 2010): 441–47. https://doi.org/10.1038/ng.571.Full Text Link to Item
-
Sanders, D., D. Simkiss, D. Braddy, S. Baccus, T. Morton, R. Cannady, N. Weaver, J. E. Rose, and E. D. Levin. “Nicotinic receptors in the habenula: importance for memory.” Neuroscience 166, no. 2 (March 17, 2010): 386–90. https://doi.org/10.1016/j.neuroscience.2009.12.035.Full Text Link to Item
-
Rose, Jed E., Alexey G. Mukhin, Stephen J. Lokitz, Timothy G. Turkington, Joseph Herskovic, Frederique M. Behm, Sudha Garg, and Pradeep K. Garg. “Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine.” Proc Natl Acad Sci U S A 107, no. 11 (March 16, 2010): 5190–95. https://doi.org/10.1073/pnas.0909184107.Full Text Link to Item
-
Levin, Edward D., Amir H. Rezvani, Yingxian Xiao, Susan Slade, Marty Cauley, Corinne Wells, Dawn Hampton, et al. “Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.” J Pharmacol Exp Ther 332, no. 3 (March 2010): 933–39. https://doi.org/10.1124/jpet.109.162073.Full Text Link to Item
-
Dehkordi, Ozra, Jed E. Rose, Kannan V. Balan, Richard M. Millis, Babur Bhatti, and Annapurni Jayam-Trouth. “Co-expression of nAChRs and molecules of the bitter taste transduction pathway by epithelial cells of intrapulmonary airways.” Life Sci 86, no. 7–8 (February 13, 2010): 281–88. https://doi.org/10.1016/j.lfs.2009.12.016.Full Text Link to Item
-
Rose, Jed E., Frédérique M. Behm, Tomas Drgon, Catherine Johnson, and George R. Uhl. “Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.” Mol Med 16, no. 7–8 (2010): 247–53. https://doi.org/10.2119/molmed.2009.00159.Full Text Link to Item
-
Uhl, George R., Tomas Drgon, Catherine Johnson, Marco F. Ramoni, Frederique M. Behm, and Jed E. Rose. “Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement.” Mol Med 16, no. 11–12 (2010): 513–26. https://doi.org/10.2119/molmed.2010.00052.Full Text Link to Item
-
Rose, Jed E., Joseph E. Herskovic, Frederique M. Behm, and Eric C. Westman. “Precessation treatment with nicotine patch significantly increases abstinence rates relative to conventional treatment.” Nicotine Tob Res 11, no. 9 (September 2009): 1067–75. https://doi.org/10.1093/ntr/ntp103.Full Text Link to Item
-
Drgon, Tomas, Catherine Johnson, Donna Walther, Anthony P. Albino, Jed E. Rose, and George R. Uhl. “Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes.” Mol Med 15, no. 7–8 (July 2009): 268–74. https://doi.org/10.2119/molmed.2009.00040.Full Text Link to Item
-
Dehkordi, Ozra, Jed E. Rose, Kannan V. Balan, Prabha Kc, Richard M. Millis, and Annapurni Jayam-Trouth. “Neuroanatomical relationships of substance P-immunoreactive intrapulmonary C-fibers and nicotinic cholinergic receptors.” J Neurosci Res 87, no. 7 (May 15, 2009): 1670–78. https://doi.org/10.1002/jnr.21967.Full Text Link to Item
-
McClernon, F Joseph, Rachel V. Kozink, Avery M. Lutz, and Jed E. Rose. “24-h smoking abstinence potentiates fMRI-BOLD activation to smoking cues in cerebral cortex and dorsal striatum.” Psychopharmacology (Berl) 204, no. 1 (May 2009): 25–35. https://doi.org/10.1007/s00213-008-1436-9.Full Text Link to Item
-
Brody, Arthur L., Mark A. Mandelkern, Matthew R. Costello, Anna L. Abrams, David Scheibal, Judah Farahi, Edythe D. London, Richard E. Olmstead, Jed E. Rose, and Alexey G. Mukhin. “Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette.” Int J Neuropsychopharmacol 12, no. 3 (April 2009): 305–16. https://doi.org/10.1017/S146114570800922X.Full Text Link to Item
-
Uhl, G. R., T. Drgon, C. Johnson, and J. E. Rose. “Nicotine abstinence genotyping: assessing the impact on smoking cessation clinical trials.” Pharmacogenomics J 9, no. 2 (April 2009): 111–15. https://doi.org/10.1038/tpj.2008.10.Full Text Link to Item
-
Levin, Edward D., Ann Petro, Amir H. Rezvani, Ninitia Pollard, N Channelle Christopher, Mariel Strauss, Jessica Avery, Jessica Nicholson, and Jed E. Rose. “Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.” Behav Brain Res 196, no. 2 (January 23, 2009): 207–13. https://doi.org/10.1016/j.bbr.2008.08.048.Full Text Link to Item
-
Rose, Jed E. “New findings on nicotine addiction and treatment.” Nebr Symp Motiv 55 (2009): 131–41. https://doi.org/10.1007/978-0-387-78748-0_8.Full Text Link to Item
-
Levin, Edward D., Susan Slade, Michael Johnson, Ann Petro, Kofi Horton, Paul Williams, Amir H. Rezvani, and Jed E. Rose. “Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats.” Eur J Pharmacol 600, no. 1–3 (December 14, 2008): 93–97. https://doi.org/10.1016/j.ejphar.2008.10.016.Full Text Link to Item
-
Rose, Jed E. “Disrupting nicotine reinforcement: from cigarette to brain.” Ann N Y Acad Sci 1141 (October 2008): 233–56. https://doi.org/10.1196/annals.1441.019.Full Text Link to Item
-
McClernon, Francis J., Rachel V. Kozink, and Jed E. Rose. “Individual differences in nicotine dependence, withdrawal symptoms, and sex predict transient fMRI-BOLD responses to smoking cues.” Neuropsychopharmacology 33, no. 9 (August 2008): 2148–57. https://doi.org/10.1038/sj.npp.1301618.Full Text Link to Item
-
Rose, J. E. “Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field.” Thorax 63, no. 8 (August 2008): 751–52.Link to Item
-
Becker, Karen M., Jed E. Rose, and Anthony P. Albino. “A randomized trial of nicotine replacement therapy in combination with reduced-nicotine cigarettes for smoking cessation.” Nicotine Tob Res 10, no. 7 (July 2008): 1139–48. https://doi.org/10.1080/14622200802123294.Full Text Link to Item
-
Uhl, George R., Qing-Rong Liu, Tomas Drgon, Catherine Johnson, Donna Walther, Jed E. Rose, Sean P. David, Ray Niaura, and Caryn Lerman. “Molecular genetics of successful smoking cessation: convergent genome-wide association study results.” Arch Gen Psychiatry 65, no. 6 (June 2008): 683–93. https://doi.org/10.1001/archpsyc.65.6.683.Full Text Link to Item
-
McClernon, F Joseph, Scott H. Kollins, Avery M. Lutz, David P. Fitzgerald, Desiree W. Murray, Christina Redman, and Jed E. Rose. “Effects of smoking abstinence on adult smokers with and without attention deficit hyperactivity disorder: results of a preliminary study.” Psychopharmacology (Berl) 197, no. 1 (March 2008): 95–105. https://doi.org/10.1007/s00213-007-1009-3.Full Text Link to Item
-
Rose, Jed E., Frederique M. Behm, Alfred N. Salley, James E. Bates, R Edward Coleman, Thomas C. Hawk, and Timothy G. Turkington. “Regional brain activity correlates of nicotine dependence.” Neuropsychopharmacology 32, no. 12 (December 2007): 2441–52. https://doi.org/10.1038/sj.npp.1301379.Full Text Link to Item
-
McClernon, F Joseph, Kent E. Hutchison, Jed E. Rose, and Rachel V. Kozink. “DRD4 VNTR polymorphism is associated with transient fMRI-BOLD responses to smoking cues.” Psychopharmacology (Berl) 194, no. 4 (November 2007): 433–41. https://doi.org/10.1007/s00213-007-0860-6.Full Text Link to Item
-
Rose, Jed E. “Multiple brain pathways and receptors underlying tobacco addiction.” Biochem Pharmacol 74, no. 8 (October 15, 2007): 1263–70. https://doi.org/10.1016/j.bcp.2007.07.039.Full Text Link to Item
-
Pettiford, Jasmine, Rachel V. Kozink, Avery M. Lutz, Scott H. Kollins, Jed E. Rose, and F Joseph McClernon. “Increases in impulsivity following smoking abstinence are related to baseline nicotine intake and boredom susceptibility.” Addict Behav 32, no. 10 (October 2007): 2351–57. https://doi.org/10.1016/j.addbeh.2007.02.004.Full Text Link to Item
-
McClernon, F Joseph, F Berry Hiott, Jim Liu, Alfred N. Salley, Frederique M. Behm, and Jed E. Rose. “Selectively reduced responses to smoking cues in amygdala following extinction-based smoking cessation: results of a preliminary functional magnetic resonance imaging study.” Addict Biol 12, no. 3–4 (September 2007): 503–12. https://doi.org/10.1111/j.1369-1600.2007.00075.x.Full Text Link to Item
-
Uhl, George R., Qing-Rong Liu, Tomas Drgon, Catherine Johnson, Donna Walther, and Jed E. Rose. “Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs.” Bmc Genet 8 (April 3, 2007): 10. https://doi.org/10.1186/1471-2156-8-10.Full Text Link to Item
-
McClernon, F Joseph, Eric C. Westman, Jed E. Rose, and Avery M. Lutz. “The effects of foods, beverages, and other factors on cigarette palatability.” Nicotine Tob Res 9, no. 4 (April 2007): 505–10. https://doi.org/10.1080/14622200701243177.Full Text Link to Item
-
Matta, Shannon G., David J. Balfour, Neal L. Benowitz, R Thomas Boyd, Jerry J. Buccafusco, Anthony R. Caggiula, Caroline R. Craig, et al. “Guidelines on nicotine dose selection for in vivo research.” Psychopharmacology (Berl) 190, no. 3 (February 2007): 269–319. https://doi.org/10.1007/s00213-006-0441-0.Full Text Link to Item
-
Rose, Jed E. “Denicotinized cigarettes: a new tool to combat cigarette addiction?” Addiction 102, no. 2 (February 2007): 181–82. https://doi.org/10.1111/j.1360-0443.2006.01727.x.Full Text Link to Item
-
McClernon, F Joseph, F Berry Hiott, Eric C. Westman, Jed E. Rose, and Edward D. Levin. “Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial.” Psychopharmacology (Berl) 189, no. 1 (November 2006): 125–33. https://doi.org/10.1007/s00213-006-0516-y.Full Text Link to Item
-
Marx, Christine E., William T. Trost, Lawrence Shampine, Frederique M. Behm, Louis A. Giordano, Mark W. Massing, and Jed E. Rose. “Neuroactive steroids, negative affect, and nicotine dependence severity in male smokers.” Psychopharmacology (Berl) 186, no. 3 (June 2006): 462–72. https://doi.org/10.1007/s00213-005-0226-x.Full Text Link to Item
-
Rose, Jed E. “Nicotine and nonnicotine factors in cigarette addiction.” Psychopharmacology (Berl) 184, no. 3–4 (March 2006): 274–85. https://doi.org/10.1007/s00213-005-0250-x.Full Text Link to Item
-
Rose, Jed E., Frederique M. Behm, Eric C. Westman, and Prity Kukovich. “Precessation treatment with nicotine skin patch facilitates smoking cessation.” Nicotine Tob Res 8, no. 1 (February 2006): 89–101. https://doi.org/10.1080/14622200500431866.Full Text Link to Item
-
Lokitz, S. J., J. E. Rose, and T. G. Turkington. “Development of a system for the non-invasive measurement of the time course of [C-11] nicotine.” Ieee Nuclear Science Symposium Conference Record 3 (December 1, 2005): 1795–99. https://doi.org/10.1109/NSSMIC.2005.1596669.Full Text
-
McClernon, F Joseph, F Berry Hiott, Scott A. Huettel, and Jed E. Rose. “Abstinence-induced changes in self-report craving correlate with event-related FMRI responses to smoking cues.” Neuropsychopharmacology 30, no. 10 (October 2005): 1940–47. https://doi.org/10.1038/sj.npp.1300780.Full Text Link to Item
-
Beckham, Jean C., Michelle E. Feldman, Scott R. Vrana, Susannah L. Mozley, Alaattin Erkanli, Carolina P. Clancy, and Jed E. Rose. “Immediate antecedents of cigarette smoking in smokers with and without posttraumatic stress disorder: a preliminary study.” Exp Clin Psychopharmacol 13, no. 3 (August 2005): 219–28. https://doi.org/10.1037/1064-1297.13.3.219.Full Text Link to Item
-
McClernon, F Joseph, and Jed E. Rose. “Mecamylamine moderates cue-induced emotional responses in smokers.” Addict Behav 30, no. 4 (May 2005): 741–53. https://doi.org/10.1016/j.addbeh.2004.08.020.Full Text Link to Item
-
Rose, Jed E. “Ethics of tobacco company funding.” Science 308, no. 5722 (April 29, 2005): 632. https://doi.org/10.1126/science.308.5722.632a.Full Text Link to Item
-
McClernon, F Joseph, Jean C. Beckham, Susannah L. Mozley, Michelle E. Feldman, Scott R. Vrana, and Jed E. Rose. “The effects of trauma recall on smoking topography in posttraumatic stress disorder and non-posttraumatic stress disorder trauma survivors.” Addict Behav 30, no. 2 (February 2005): 247–57. https://doi.org/10.1016/j.addbeh.2004.05.013.Full Text Link to Item
-
Rose, J. E., and F. M. Behm. “Erratum: "Effects of low nicotine content cigarettes on smoke intake" (Nicotine & Tobacco Research (2004) vol. 6 (2) (309-319)).” Nicotine and Tobacco Research 6, no. 3 (June 1, 2004): 575. https://doi.org/10.1080/14622200410001703160.Full Text
-
Rose, Jed E., and Frederique M. Behm. “Extinguishing the rewarding value of smoke cues: pharmacological and behavioral treatments.” Nicotine Tob Res 6, no. 3 (June 2004): 523–32. https://doi.org/10.1080/14622200410001696501.Full Text Link to Item
-
McClernon, F Joseph, Eric C. Westman, and Jed E. Rose. “The effects of controlled deep breathing on smoking withdrawal symptoms in dependent smokers.” Addict Behav 29, no. 4 (June 2004): 765–72. https://doi.org/10.1016/j.addbeh.2004.02.005.Full Text Link to Item
-
Rose, Jed, and Frederique Behm. “Effects of low nicotine content cigarettes on smoke intake.” Nicotine Tob Res 6, no. 2 (April 2004): 309–19. https://doi.org/10.1080/14622200410001676378.Full Text Link to Item
-
Rose, Jed E., Lisa H. Brauer, Frederique M. Behm, Matthew Cramblett, Kevin Calkins, and Dawn Lawhon. “Psychopharmacological interactions between nicotine and ethanol.” Nicotine Tob Res 6, no. 1 (February 2004): 133–44. https://doi.org/10.1080/14622200310001656957.Full Text Link to Item
-
Rose, Jed E., Frederique M. Behm, Eric C. Westman, James E. Bates, and Al Salley. “Pharmacologic and sensorimotor components of satiation in cigarette smoking.” Pharmacol Biochem Behav 76, no. 2 (September 2003): 243–50. https://doi.org/10.1016/j.pbb.2003.07.002.Full Text Link to Item
-
Rose, Jed E., Frederique M. Behm, Eric C. Westman, and James E. Bates. “Mecamylamine acutely increases human intravenous nicotine self-administration.” Pharmacol Biochem Behav 76, no. 2 (September 2003): 307–13. https://doi.org/10.1016/j.pbb.2003.08.011.Full Text Link to Item
-
Levin, Edward D., Amir H. Rezvani, Daniel Montoya, Jed E. Rose, and H Scott Swartzwelder. “Adolescent-onset nicotine self-administration modeled in female rats.” Psychopharmacology (Berl) 169, no. 2 (September 2003): 141–49. https://doi.org/10.1007/s00213-003-1486-y.Full Text Link to Item
-
Yang, Yen Kuang, Joseph P. McEvoy, William H. Wilson, Edward D. Levin, and Jed E. Rose. “Reliabilities and intercorrelations of reported and objective measures of smoking in patients with schizophrenia.” Schizophr Res 60, no. 1 (March 1, 2003): 9–12. https://doi.org/10.1016/s0920-9964(02)00208-6.Full Text Link to Item
-
Rose, Jed E., Frederique M. Behm, Eric C. Westman, Roy J. Mathew, Edythe D. London, Thomas C. Hawk, Timothy G. Turkington, and R Edward Coleman. “PET studies of the influences of nicotine on neural systems in cigarette smokers.” Am J Psychiatry 160, no. 2 (February 2003): 323–33. https://doi.org/10.1176/appi.ajp.160.2.323.Full Text Link to Item
-
Rose, Jed E., Lisa H. Brauer, Frederique M. Behm, Matthew Cramblett, Kevin Calkins, and Dawn Lawhon. “Potentiation of nicotine reward by alcohol.” Alcohol Clin Exp Res 26, no. 12 (December 2002): 1930–31. https://doi.org/10.1097/01.ALC.0000040982.92057.52.Full Text Link to Item
-
Blomqvist, Ola, Carlos A. Hernandez-Avila, Jeffrey Van Kirk, Jed E. Rose, and Henry R. Kranzler. “Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol.” Alcohol Clin Exp Res 26, no. 3 (March 2002): 326–31.Link to Item
-
Brauer, L. H., M. J. Cramblett, D. A. Paxton, and J. E. Rose. “Haloperidol reduces smoking of both nicotine-containing and denicotinized cigarettes.” Psychopharmacology (Berl) 159, no. 1 (December 2001): 31–37. https://doi.org/10.1007/s002130100894.Full Text Link to Item
-
Rose, J. E., F. M. Behm, C. Ramsey, and J. C. Ritchie. “Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.” Nicotine Tob Res 3, no. 4 (November 2001): 383–90. https://doi.org/10.1080/14622200110087277.Full Text Link to Item
-
Westman, E. C., K. F. Tomlin, C. E. Perkins, and J. E. Rose. “Oral nicotine solution for smoking cessation: a pilot tolerability study.” Nicotine Tob Res 3, no. 4 (November 2001): 391–96. https://doi.org/10.1080/14622200126973.Full Text Link to Item
-
Brauer, L. H., F. M. Behm, J. D. Lane, E. C. Westman, C. Perkins, and J. E. Rose. “Individual differences in smoking reward from de-nicotinized cigarettes.” Nicotine Tob Res 3, no. 2 (May 2001): 101–9. https://doi.org/10.1080/14622200123249.Full Text Link to Item
-
Rose, J. E., F. M. Behm, and E. C. Westman. “Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking.” Pharmacol Biochem Behav 68, no. 2 (February 2001): 187–97. https://doi.org/10.1016/s0091-3057(00)00465-2.Full Text Link to Item
-
Levin, E. D., T. Mead, A. H. Rezvani, J. E. Rose, C. Gallivan, and R. Gross. “The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats.” Physiol Behav 71, no. 5 (December 2000): 565–70. https://doi.org/10.1016/s0031-9384(00)00382-6.Full Text Link to Item
-
Rose, J. E., F. M. Behm, E. C. Westman, and M. Johnson. “Dissociating nicotine and nonnicotine components of cigarette smoking.” Pharmacol Biochem Behav 67, no. 1 (September 2000): 71–81. https://doi.org/10.1016/s0091-3057(00)00301-4.Full Text Link to Item
-
Westman, E. C., K. F. Tomlin, and J. E. Rose. “Combining the nicotine inhaler and nicotine patch for smoking cessation.” American Journal of Health Behavior 24, no. 2 (January 1, 2000): 114–19. https://doi.org/10.5993/AJHB.24.2.4.Full Text
-
Rose, J. E., F. M. Behm, E. C. Westman, and R. E. Coleman. “Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: implications for addiction.” Drug Alcohol Depend 56, no. 2 (September 1, 1999): 99–107. https://doi.org/10.1016/s0376-8716(99)00025-3.Full Text Link to Item
-
Brauer, L. H., F. M. Behm, E. C. Westman, P. Patel, and J. E. Rose. “Naltrexone blockade of nicotine effects in cigarette smokers.” Psychopharmacology (Berl) 143, no. 4 (April 1999): 339–46. https://doi.org/10.1007/s002130050957.Full Text Link to Item
-
Rose, J. E., E. C. Westman, F. M. Behm, M. P. Johnson, and J. S. Goldberg. “Blockade of smoking satisfaction using the peripheral nicotinic antagonist trimethaphan.” Pharmacol Biochem Behav 62, no. 1 (January 1999): 165–72. https://doi.org/10.1016/s0091-3057(98)00153-1.Full Text Link to Item
-
Levin, E. D., C. K. Conners, D. Silva, S. C. Hinton, W. H. Meck, J. March, and J. E. Rose. “Transdermal nicotine effects on attention.” Psychopharmacology (Berl) 140, no. 2 (November 1998): 135–41. https://doi.org/10.1007/s002130050750.Full Text Link to Item
-
Rose, J. E., F. M. Behm, and E. C. Westman. “Nicotine-mecamylamine treatment for smoking cessation: the role of pre-cessation therapy.” Exp Clin Psychopharmacol 6, no. 3 (August 1998): 331–43. https://doi.org/10.1037//1064-1297.6.3.331.Full Text Link to Item
-
Dretchen, K. L., J. Slade, D. A. Kessler, C. E. Koop, D. M. Burns, P. O. Safir, J. E. Henningfield, et al. “Conference on tobacco dependence: Innovative regulatory approaches to reduce death and disease: Selected excerpts from conference proceedings.” Food and Drug Law Journal 53, no. SUPPL. (1998): 115–37.
-
Perkins, K. A. “Membership of tobacco industry scientists in scientific societies.” Addiction 92, no. 5 (May 1997): 517–20. https://doi.org/10.1111/j.1360-0443.1997.tb02903.x.Full Text Link to Item
-
Rose, J. E., and W. A. Corrigall. “Nicotine self-administration in animals and humans: similarities and differences.” Psychopharmacology (Berl) 130, no. 1 (March 1997): 28–40. https://doi.org/10.1007/s002130050209.Full Text Link to Item
-
Westman, E. C., F. M. Behm, D. L. Simel, and J. E. Rose. “Smoking behavior on the first day of a quit attempt predicts long-term abstinence.” Arch Intern Med 157, no. 3 (February 10, 1997): 335–40.Link to Item
-
Levin, E. D., J. E. Rose, P. Lippelio, and J. Robinson. “Nicotine and neurobehavioral function.” Drug Development Research 38, no. 3–4 (December 1, 1996): 135. https://doi.org/10.1002/(SICI)1098-2299(199607/08)38:3/4<135::AID-DDR1>3.0.CO;2-N.Full Text
-
Westman, E. C., F. M. Behm, and J. E. Rose. “Airway sensory replacement as a treatment for smoking cessation.” Drug Development Research 38, no. 3–4 (December 1, 1996): 257–62. https://doi.org/10.1002/(SICI)1098-2299(199607/08)38:3/4<257::AID-DDR14>3.0.CO;2-W.Full Text
-
Lane, J. D., E. C. Opara, J. E. Rose, and F. Behm. “Quitting smoking raises whole blood glutathione.” Physiol Behav 60, no. 5 (November 1996): 1379–81. https://doi.org/10.1016/s0031-9384(96)00328-9.Full Text Link to Item
-
Levin, E. D., W. Wilson, J. E. Rose, and J. McEvoy. “Nicotine-haloperidol interactions and cognitive performance in schizophrenics.” Neuropsychopharmacology 15, no. 5 (November 1996): 429–36. https://doi.org/10.1016/S0893-133X(96)00018-8.Full Text Link to Item
-
Westman, E. C., and J. E. Rose. “Do heavy smokers need a higher replacement dose of nicotine to quit?” Jama 275, no. 24 (June 26, 1996): 1882–83.Link to Item
-
Westman, E. C., F. M. Behm, and J. E. Rose. “Dissociating the nicotine and airway sensory effects of smoking.” Pharmacol Biochem Behav 53, no. 2 (February 1996): 309–15. https://doi.org/10.1016/0091-3057(95)02027-6.Full Text Link to Item
-
Rose, J. E. “Nicotine addiction and treatment.” Annu Rev Med 47 (1996): 493–507. https://doi.org/10.1146/annurev.med.47.1.493.Full Text Link to Item
-
Rose, J. E., E. C. Westman, and F. M. Behm. “Nicotine/mecamylamine combination treatment for smoking cessation.” Drug Development Research 38, no. 3–4 (January 1, 1996): 243–56. https://doi.org/10.1002/(sici)1098-2299(199607/08)38:3/4<243::aid-ddr13>3.0.co;2-%23.Full Text
-
Conners, C. K., E. D. Levin, E. Sparrow, S. C. Hinton, D. Erhardt, W. H. Meck, J. E. Rose, and J. March. “Nicotine and attention in adult attention deficit hyperactivity disorder (ADHD).” Psychopharmacol Bull 32, no. 1 (1996): 67–73.Link to Item
-
Levin, E. D., C. K. Conners, E. Sparrow, S. C. Hinton, D. Erhardt, W. H. Meck, J. E. Rose, and J. March. “Nicotine effects on adults with attention-deficit/hyperactivity disorder.” Psychopharmacology (Berl) 123, no. 1 (January 1996): 55–63. https://doi.org/10.1007/BF02246281.Full Text Link to Item
-
Beckham, J. C., A. A. Roodman, R. H. Shipley, M. A. Hertzberg, G. H. Cunha, H. S. Kudler, E. D. Levin, J. E. Rose, and J. A. Fairbank. “Smoking in Vietnam combat veterans with post-traumatic stress disorder.” J Trauma Stress 8, no. 3 (July 1995): 461–72. https://doi.org/10.1007/BF02102970.Full Text Link to Item
-
Levin, E. D., and J. E. Rose. “Acute and chronic nicotinic interactions with dopamine systems and working memory performance.” Ann N Y Acad Sci 757 (May 10, 1995): 245–52. https://doi.org/10.1111/j.1749-6632.1995.tb17481.x.Full Text Link to Item
-
Rose, J. E., E. D. Levin, F. M. Behm, E. C. Westman, R. M. Stein, J. D. Lane, and G. V. Ripka. “Combined administration of agonist-antagonist as a method of regulating receptor activation.” Ann N Y Acad Sci 757 (May 10, 1995): 218–21. https://doi.org/10.1111/j.1749-6632.1995.tb17478.x.Full Text Link to Item
-
McEvoy, J. P., O. Freudenreich, E. D. Levin, and J. E. Rose. “Haloperidol increases smoking in patients with schizophrenia.” Psychopharmacology (Berl) 119, no. 1 (May 1995): 124–26. https://doi.org/10.1007/BF02246063.Full Text Link to Item
-
Westman, E. C., F. M. Behm, and J. E. Rose. “Airway sensory replacement combined with nicotine replacement for smoking cessation. A randomized, placebo-controlled trial using a citric acid inhaler.” Chest 107, no. 5 (May 1995): 1358–64. https://doi.org/10.1378/chest.107.5.1358.Full Text Link to Item
-
McEvoy, J., O. Freudenreich, M. McGee, C. VanderZwaag, E. Levin, and J. Rose. “Clozapine decreases smoking in patients with chronic schizophrenia.” Biol Psychiatry 37, no. 8 (April 15, 1995): 550–52. https://doi.org/10.1016/0006-3223(94)00365-A.Full Text Link to Item
-
Lane, J. D., J. C. Lefebvre, J. E. Rose, and F. J. Keefe. “Effects of Cigarette Smoking on Perception of Thermal Pain.” Experimental and Clinical Psychopharmacology 3, no. 2 (January 1, 1995): 140–47. https://doi.org/10.1037/1064-1297.3.2.140.Full Text
-
Lane, J. D., and J. E. Rose. “Effects of Daily Caffeine Intake on Smoking Behavior in the Natural Environment.” Experimental and Clinical Psychopharmacology 3, no. 1 (January 1, 1995): 49–55. https://doi.org/10.1037/1064-1297.3.1.49.Full Text
-
Westman, E. C., E. D. Levin, and J. E. Rose. “Nicotine as a therapeutic drug.” N C Med J 56, no. 1 (January 1995): 48–51.Link to Item
-
Levin, E. D., J. E. Rose, and L. Abood. “Effects of nicotinic dimethylaminoethyl esters on working memory performance of rats in the radial-arm maze.” Pharmacol Biochem Behav 51, no. 2–3 (1995): 369–73. https://doi.org/10.1016/0091-3057(94)00406-9.Full Text Link to Item
-
Rose, J. E., F. M. Behm, E. C. Westman, E. D. Levin, R. M. Stein, and G. V. Ripka. “Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone.” Clin Pharmacol Ther 56, no. 1 (July 1994): 86–99. https://doi.org/10.1038/clpt.1994.105.Full Text Link to Item
-
Rose, J. E., and F. M. Behm. “Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms.” Drug Alcohol Depend 34, no. 3 (February 1994): 225–29. https://doi.org/10.1016/0376-8716(94)90160-0.Full Text Link to Item
-
Levin, E. D., E. C. Westman, R. M. Stein, E. Carnahan, M. Sanchez, S. Herman, F. M. Behm, and J. E. Rose. “Nicotine skin patch treatment increases abstinence, decreases withdrawal symptoms, and attenuates rewarding effects of smoking.” J Clin Psychopharmacol 14, no. 1 (February 1994): 41–49.Link to Item
-
Behm, F. M., and J. E. Rose. “Reducing Craving for Cigarettes While Decreasing Smoke Intake Using Capsaicin-Enhanced Low Tar Cigarettes.” Experimental and Clinical Psychopharmacology 2, no. 2 (January 1, 1994): 143–53. https://doi.org/10.1037/1064-1297.2.2.143.Full Text
-
Brucato, F. H., E. D. Levin, J. E. Rose, and H. S. Swartzwelder. “Intracerebroventricular nicotine and mecamylamine alter radial‐arm maze performance in rats.” Drug Development Research 31, no. 1 (January 1, 1994): 18–23. https://doi.org/10.1002/ddr.430310104.Full Text
-
Rose, J. E., F. M. Behm, E. C. Westman, E. D. Levin, R. M. Stein, J. D. Lane, and G. V. Ripka. “Combined Effects of Nicotine and Mecamylamine in Attenuating Smoking Satisfaction.” Experimental and Clinical Psychopharmacology 2, no. 4 (January 1, 1994): 328–44. https://doi.org/10.1037/1064-1297.2.4.328.Full Text
-
Levin, E. D., N. C. Christopher, S. J. Briggs, and J. E. Rose. “Chronic nicotine reverses working memory deficits caused by lesions of the fimbria or medial basalocortical projection.” Brain Res Cogn Brain Res 1, no. 3 (October 1993): 137–43. https://doi.org/10.1016/0926-6410(93)90021-v.Full Text Link to Item
-
Rose, J. E., E. D. Levin, and N. Benowitz. “Saliva nicotine as an index of plasma levels in nicotine skin patch users.” Ther Drug Monit 15, no. 5 (October 1993): 431–35. https://doi.org/10.1097/00007691-199310000-00012.Full Text Link to Item
-
Levin, E. D., F. Behm, E. Carnahan, R. LeClair, R. Shipley, and J. E. Rose. “Clinical trials using ascorbic acid aerosol to aid smoking cessation.” Drug Alcohol Depend 33, no. 3 (October 1993): 211–23. https://doi.org/10.1016/0376-8716(93)90108-3.Full Text Link to Item
-
Westman, E. C., E. D. Levin, and J. E. Rose. “The nicotine patch in smoking cessation. A randomized trial with telephone counseling.” Arch Intern Med 153, no. 16 (August 23, 1993): 1917–23.Link to Item
-
Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Chronic nicotinic stimulation and blockade effects on working memory.” Behav Pharmacol 4, no. 2 (April 1993): 179–82.Link to Item
-
Rose, J. E., F. M. Behm, and E. D. Levin. “Role of nicotine dose and sensory cues in the regulation of smoke intake.” Pharmacol Biochem Behav 44, no. 4 (April 1993): 891–900. https://doi.org/10.1016/0091-3057(93)90021-k.Full Text Link to Item
-
Behm, F. M., C. Schur, E. D. Levin, D. P. Tashkin, and J. E. Rose. “Clinical evaluation of a citric acid inhaler for smoking cessation.” Drug Alcohol Depend 31, no. 2 (January 1993): 131–38. https://doi.org/10.1016/0376-8716(93)90065-x.Full Text Link to Item
-
Lane, J. D., E. C. Westman, G. V. Ripka, J. Wu, C. C. Chiang, and J. E. Rose. “Pharmacokinetics of a transdermal nicotine patch compared to nicotine gum.” Drug Development and Industrial Pharmacy 19, no. 16 (January 1, 1993): 1999–2010. https://doi.org/10.3109/03639049309069337.Full Text
-
Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Prenatal nicotine exposure and cognitive performance in rats.” Neurotoxicol Teratol 15, no. 4 (1993): 251–60. https://doi.org/10.1016/0892-0362(93)90006-a.Full Text Link to Item
-
Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Sertraline attenuates hyperphagia in rats following nicotine withdrawal.” Pharmacol Biochem Behav 44, no. 1 (January 1993): 51–61. https://doi.org/10.1016/0091-3057(93)90280-7.Full Text Link to Item
-
Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Persistence of chronic nicotine-induced cognitive facilitation.” Behav Neural Biol 58, no. 2 (September 1992): 152–58. https://doi.org/10.1016/0163-1047(92)90399-o.Full Text Link to Item
-
Rose, J. E., and E. D. Levin. “Concurrent agonist-antagonist administration for the analysis and treatment of drug dependence.” Pharmacol Biochem Behav 41, no. 1 (January 1992): 219–26. https://doi.org/10.1016/0091-3057(92)90086-u.Full Text Link to Item
-
Stolerman, I., and J. Rose. “Nicotine psychopharmacology.” Journal of Psychopharmacology 6, no. 4 (January 1, 1992): 545–46. https://doi.org/10.1177/026988119200600416.Full Text
-
Tashkin, D. P., F. Gliederer, J. Rose, P. Chang, K. K. Hui, J. L. Yu, and T. C. Wu. “Tar, CO and delta 9THC delivery from the 1st and 2nd halves of a marijuana cigarette.” Pharmacol Biochem Behav 40, no. 3 (November 1991): 657–61. https://doi.org/10.1016/0091-3057(91)90378-f.Full Text Link to Item
-
Tashkin, D. P., F. Gliederer, J. Rose, P. Change, K. K. Hui, J. L. Yu, and T. C. Wu. “Effects of varying marijuana smoking profile on deposition of tar and absorption of CO and delta-9-THC.” Pharmacol Biochem Behav 40, no. 3 (November 1991): 651–56. https://doi.org/10.1016/0091-3057(91)90377-e.Full Text Link to Item
-
Levin, E. D., and J. E. Rose. “Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze.” Brain Res Bull 27, no. 1 (July 1991): 125–28. https://doi.org/10.1016/0361-9230(91)90293-s.Full Text Link to Item
-
Levin, E. D., J. E. Rose, F. Behm, and N. H. Caskey. “The effects of smoking-related sensory cues on psychological stress.” Pharmacol Biochem Behav 39, no. 2 (June 1991): 265–68. https://doi.org/10.1016/0091-3057(91)90177-4.Full Text Link to Item
-
Rose, J. E., and E. D. Levin. “Inter-relationships between conditioned and primary reinforcement in the maintenance of cigarette smoking.” Br J Addict 86, no. 5 (May 1991): 605–9. https://doi.org/10.1111/j.1360-0443.1991.tb01816.x.Full Text Link to Item
-
Rose, J. E., and F. M. Behm. “Psychophysiological interactions between caffeine and nicotine.” Pharmacol Biochem Behav 38, no. 2 (February 1991): 333–37. https://doi.org/10.1016/0091-3057(91)90287-c.Full Text Link to Item
-
Levin, E. D., and J. E. Rose. “Interactive effects of D1 and D2 agonists with scopolamine on radial-arm maze performance.” Pharmacol Biochem Behav 38, no. 2 (February 1991): 243–46. https://doi.org/10.1016/0091-3057(91)90272-4.Full Text Link to Item
-
Levin, E. D., S. R. McGurk, J. E. Rose, and L. L. Butcher. “Cholinergic-dopaminergic interactions in cognitive performance.” Behav Neural Biol 54, no. 3 (November 1990): 271–99. https://doi.org/10.1016/0163-1047(90)90639-n.Full Text Link to Item
-
Levin, E. D., F. Behm, and J. E. Rose. “The use of flavor in cigarette substitutes.” Drug Alcohol Depend 26, no. 2 (October 1990): 155–60. https://doi.org/10.1016/0376-8716(90)90122-u.Full Text Link to Item
-
Levin, E. D., J. E. Rose, and F. Behm. “Development of a citric acid aerosol as a smoking cessation aid.” Drug Alcohol Depend 25, no. 3 (June 1990): 273–79. https://doi.org/10.1016/0376-8716(90)90152-5.Full Text Link to Item
-
Rose, J. E., E. D. Levin, F. M. Behm, C. Adivi, and C. Schur. “Transdermal nicotine facilitates smoking cessation.” Clin Pharmacol Ther 47, no. 3 (March 1990): 323–30. https://doi.org/10.1038/clpt.1990.35.Full Text Link to Item
-
Levin, E. D., C. Lee, J. E. Rose, A. Reyes, G. Ellison, M. Jarvik, and E. Gritz. “Chronic nicotine and withdrawal effects on radial-arm maze performance in rats.” Behav Neural Biol 53, no. 2 (March 1990): 269–76. https://doi.org/10.1016/0163-1047(90)90509-5.Full Text Link to Item
-
Behm, F. M., E. D. Levin, Y. K. Lee, and J. E. Rose. “Low-nicotine regenerated smoke aerosol reduces desire for cigarettes.” J Subst Abuse 2, no. 2 (1990): 237–47. https://doi.org/10.1016/s0899-3289(05)80058-6.Full Text Link to Item
-
Levin, E. D., J. E. Rose, S. R. McGurk, and L. L. Butcher. “Characterization of the cognitive effects of combined muscarinic and nicotinic blockade.” Behav Neural Biol 53, no. 1 (January 1990): 103–12. https://doi.org/10.1016/0163-1047(90)90865-4.Full Text Link to Item
-
Pomerleau, O. F., J. E. Rose, C. S. Pomerleau, and M. J. Majchrzak. “A noninvasive method for delivering controlled doses of nicotine via cigarette smoke.” Behavior Research Methods, Instruments, &Amp; Computers 21, no. 6 (November 1, 1989): 598–602. https://doi.org/10.3758/BF03210582.Full Text
-
Levin, E. D., S. R. McGurk, J. E. Rose, and L. L. Butcher. “Reversal of a mecamylamine-induced cognitive deficit with the D2 agonist, LY 171555.” Pharmacol Biochem Behav 33, no. 4 (August 1989): 919–22. https://doi.org/10.1016/0091-3057(89)90494-2.Full Text Link to Item
-
Levin, E. D., J. E. Rose, and F. Behm. “Controlling puff volume without disrupting smoking topography.” Behavior Research Methods, Instruments, &Amp; Computers 21, no. 3 (May 1, 1989): 383–86. https://doi.org/10.3758/BF03202801.Full Text
-
Rose, J. E., A. Sampson, E. D. Levin, and J. E. Henningfield. “Mecamylamine increases nicotine preference and attenuates nicotine discrimination.” Pharmacol Biochem Behav 32, no. 4 (April 1989): 933–38. https://doi.org/10.1016/0091-3057(89)90061-0.Full Text Link to Item
-
Bennett, R. H., D. R. Cherek, J. D. Roache, and J. E. Rose. “Effects of controlled nicotine doses upon punished and non-punished responding in humans.” Nida Res Monogr 95 (1989): 438–39.Link to Item
-
Pomerleau, O. F., C. S. Pomerleau, and J. E. Rose. “Methodological review. Controlled dosing of nicotine: A review of problems and progress.” Annals of Behavioral Medicine 11, no. 4 (January 1, 1989): 158–62. https://doi.org/10.1207/s15324796abm1104_6.Full Text
-
Jarvik, M. E., N. H. Caskey, J. E. Rose, J. E. Herskovic, and M. Sadeghpour. “Anxiolytic effects of smoking associated with four stressors.” Addict Behav 14, no. 4 (1989): 379–86. https://doi.org/10.1016/0306-4603(89)90025-7.Full Text Link to Item
-
Gritz, E. R., A. Ippoliti, M. E. Jarvik, J. E. Rose, S. Shiffman, A. Harrison, and H. Van Vunakis. “The effect of nicotine on the delay of gastric emptying.” Aliment Pharmacol Ther 2, no. 2 (April 1988): 173–78. https://doi.org/10.1111/j.1365-2036.1988.tb00685.x.Full Text Link to Item
-
Wu, T. C., D. P. Tashkin, B. Djahed, and J. E. Rose. “Pulmonary hazards of smoking marijuana as compared with tobacco.” N Engl J Med 318, no. 6 (February 11, 1988): 347–51. https://doi.org/10.1056/NEJM198802113180603.Full Text Link to Item
-
Gorelick, D. A., J. Rose, and M. E. Jarvik. “Effect of naloxone on cigarette smoking.” J Subst Abuse 1, no. 2 (1988): 153–59. https://doi.org/10.1016/s0899-3289(88)80018-x.Full Text Link to Item
-
Rose, J. E. “The role of upper airway stimulation in smoking.” Prog Clin Biol Res 261 (1988): 95–106.Link to Item
-
Wu, T. C., D. P. Tashkin, J. E. Rose, and B. Djahed. “Influence of marijuana potency and amount of cigarette consumed on marijuana smoking pattern.” J Psychoactive Drugs 20, no. 1 (1988): 43–46. https://doi.org/10.1080/02791072.1988.10524370.Full Text Link to Item
-
Rose, J. E., and C. S. Hickman. “Citric acid aerosol as a potential smoking cessation aid.” Chest 92, no. 6 (December 1987): 1005–8. https://doi.org/10.1378/chest.92.6.1005.Full Text Link to Item
-
Rose, J. E., and F. Behm. “Refined cigarette smoke as a method for reducing nicotine intake.” Pharmacol Biochem Behav 28, no. 2 (October 1987): 305–10. https://doi.org/10.1016/0091-3057(87)90229-2.Full Text Link to Item
-
Rose, J. E., T. C. Wu, B. Djahed, and D. P. Tashkin. “Noninvasive measurement of smokers' tar and nicotine intake.” Behavior Research Methods, Instruments, &Amp; Computers 19, no. 3 (May 1, 1987): 295–99. https://doi.org/10.3758/BF03202564.Full Text
-
Rose, J. E. “Cigarette smoking blocks caffeine-induced arousal.” Alcohol Drug Res 7, no. 1 (1987): 49–55.Link to Item
-
Herskovic, J. E., J. E. Rose, and M. E. Jarvik. “Cigarette desirability and nicotine preference in smokers.” Pharmacol Biochem Behav 24, no. 2 (February 1986): 171–75. https://doi.org/10.1016/0091-3057(86)90333-3.Full Text Link to Item
-
Rose, J. E., J. E. Herskovic, Y. Trilling, and M. E. Jarvik. “Transdermal nicotine reduces cigarette craving and nicotine preference.” Clin Pharmacol Ther 38, no. 4 (October 1985): 450–56. https://doi.org/10.1038/clpt.1985.203.Full Text Link to Item
-
Rose, J. E., D. P. Tashkin, A. Ertle, M. C. Zinser, and R. Lafer. “Sensory blockade of smoking satisfaction.” Pharmacol Biochem Behav 23, no. 2 (August 1985): 289–93. https://doi.org/10.1016/0091-3057(85)90572-6.Full Text Link to Item
-
Mintz, J., G. Boyd, J. E. Rose, V. C. Charuvastra, and M. E. Jarvik. “Alcohol increases cigarette smoking: a laboratory demonstration.” Addict Behav 10, no. 3 (1985): 203–7. https://doi.org/10.1016/0306-4603(85)90001-2.Full Text Link to Item
-
Rose, J. E., M. E. Jarvik, and K. D. Rose. “Transdermal administration of nicotine.” Drug Alcohol Depend 13, no. 3 (May 1984): 209–13. https://doi.org/10.1016/0376-8716(84)90061-9.Full Text Link to Item
-
Rose, J. E. “Discriminability of nicotine in tobacco smoke: implications for titration.” Addict Behav 9, no. 2 (1984): 189–93. https://doi.org/10.1016/0306-4603(84)90056-x.Full Text Link to Item
-
Rose, J. E., M. C. Zinser, D. P. Tashkin, R. Newcomb, and A. Ertle. “Subjective response to cigarette smoking following airway anesthetization.” Addict Behav 9, no. 2 (1984): 211–15. https://doi.org/10.1016/0306-4603(84)90060-1.Full Text Link to Item
-
Rose, J. E., M. E. Jarvik, and S. Ananda. “Nicotine preference increases after cigarette deprivation.” Pharmacol Biochem Behav 20, no. 1 (January 1984): 55–58. https://doi.org/10.1016/0091-3057(84)90100-x.Full Text Link to Item
-
Gritz, E. R., J. E. Rose, and M. E. Jarvik. “Regulation of tobacco smoke intake with paced cigarette presentation.” Pharmacol Biochem Behav 18, no. 3 (March 1983): 457–62. https://doi.org/10.1016/0091-3057(83)90469-0.Full Text Link to Item
-
Jarvik, M. E., E. R. Gritz, and J. E. Rose. “Cigarette smoking behavior in conjoined twins.” Acta Genet Med Gemellol (Roma) 32, no. 3–4 (1983): 239–43. https://doi.org/10.1017/s0001566000005092.Full Text Link to Item
-
Rose, J. E. “Analysis of reinforcement by varying smoke component concentrations.” Nida Res Monogr 48 (1983): 39–49.Link to Item
-
Rose, J. E., S. Ananda, and M. E. Jarvik. “Cigarette smoking during anxiety-provoking and monotonous tasks.” Addict Behav 8, no. 4 (1983): 353–59. https://doi.org/10.1016/0306-4603(83)90035-7.Full Text Link to Item
-
Rose, J. E., R. L. Lafer, and M. E. Jarvik. “A smoke-mixing device for measuring nicotine preference.” Behavior Research Methods &Amp; Instrumentation 14, no. 6 (November 1, 1982): 501–3. https://doi.org/10.3758/BF03203412.Full Text
-
Rose, J. E., and E. Fantino. “Self-punitive behavior in humans: Effects of a self-fulfilling prophecy.” Learning and Motivation 12, no. 2 (January 1, 1981): 212–38. https://doi.org/10.1016/0023-9690(81)90019-9.Full Text
-
-
Book Sections
-
Rose, J. E. “Nicotine replacement therapies and other nicotinic strategies.” In Medication Treatments for Nicotine Dependence, 63–74, 2006.
-
Rose, J. E. “Evaluation of pharmacologic treatments for smoking cessation.” In Nicotinic Receptors in the Nervous System, 217–26, 2001.
-
-
Conference Papers
-
Zuo, Yantao, Alexey G. Mukhin, Hannah Berg, Janiece D. Morgan, Akiva Mintz, Jed E. Rose, and Kiran Kumar Solingapuram Sai. “Comparison of brain nicotine uptake from electronic cigarettes and combustible cigarettes.” In Neuropsychopharmacology, 47:1939–44, 2022. https://doi.org/10.1038/s41386-022-01410-5.Full Text Link to Item
-
Salzberger, T., S. Cano, L. Abetz-Webb, E. Afolalu, C. Chrea, R. Weitkunat, K. Fagerström, and J. Rose. “Addressing traceability in social measurement: Establishing a common metric for dependence.” In Journal of Physics: Conference Series, Vol. 1379, 2019. https://doi.org/10.1088/1742-6596/1379/1/012024.Full Text
-
-
- Teaching & Mentoring
-
Recent Courses
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.