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Mark Zachary Rosenthal

Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology
Box 102505 Med Ctr, Durham, NC 27710
2400 Pratt Street, North Pavillion 6th Floor Room 6043, Durham, NC 27705

Overview


Misophonia, emotional functioning, borderline personality disorder, digital health, behavioral therapies, cognitive behavioral therapy (CBT) and dialectical behavior therapy (DBT)

Current Duke Appointments & Affiliations


Professor in Psychiatry and Behavioral Sciences · 2026 - Present Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology, Psychiatry & Behavioral Sciences
Director of the Psychology Clinic in the Department of Psychology & Neuroscience · 2026 - Present Psychology & Neuroscience, Trinity College of Arts & Sciences
Professor of Psychology and Neuroscience · 2026 - Present Psychology & Neuroscience, Trinity College of Arts & Sciences

Recent News Items


Published July 17, 2025
Spectrum News
Teen Works to Help Others with Misophonia
Published January 1, 2025
The Asterisk
The Unbearable Loudness of Chewing
Published August 28, 2024
Duke School of Medicine
Actor Melissa Gilbert on Struggles With Misophonia

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Recent Scholarly Works


Patterns of shared and differential neural activity in misophonia and non-misophonic clinical emotional dysregulation.

Journal article BMC Psychiatry · June 29, 2026 Misophonia is a poorly understood clinical condition characterized by reduced tolerance to select trigger sounds. Whether misophonic distress and its regulation involve unique neural mechanisms compared to other forms of emotion dysregulation remains uncle ... Full text Link to item Cite

Real-time emotional responses to trigger sounds in misophonia: An ecological momentary assessment study.

Journal article J Affect Disord · June 15, 2026 Although misophonia is characterized by intense negative emotional responses, the temporal dynamics of these experiences in naturalistic settings are poorly understood. This study utilized ecological momentary assessment (EMA) to characterize the real-time ... Full text Link to item Cite

Transdiagnostic mechanisms of decreased sound tolerance

Journal article Nature Reviews Psychology · June 1, 2026 Decreased sound tolerance — a group of conditions characterized by a reduced ability to cope with everyday sounds that are tolerable for most people — often co-occurs with mental health disorders such as autism spectrum disorder, attention deficit hyperact ... Full text Cite
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Recent Grants


Duke University Psychiatry Physician-Scientist Residency Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Mental Health · 2024 - 2029

Semantic Sound Suppression Using a Neural Network for Misophonia

ResearchPrincipal Investigator · Awarded by University of Washington · 2025 - 2028

Longitudinal Incidence and Prevalence of Misophonia in a Nationally Representative Sample of U.S. Adults

ResearchCo Investigator · Awarded by The REAM Foundation · 2024 - 2027

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Education


University of Nevada, Reno · 2002 Ph.D.