Skip to main content

Mark Zachary Rosenthal

Associate Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology
Box 102505 Med Ctr, Durham, NC 27710
2400 Pratt Street, North Pavillion 6th Floor Room 6043, Durham, NC 27705

Selected Publications


An experimental examination of neurostimulation and cognitive restructuring as potential components for Misophonia interventions.

Journal Article J Affect Disord · April 1, 2024 Misophonia is a disorder of decreased tolerance to certain aversive, repetitive common sounds, or to stimuli associated with these sounds. Two matched groups of adults (29 participants with misophonia and 30 clinical controls with high emotion dysregulatio ... Full text Link to item Cite

Misophonia is related to stress but not directly with traumatic stress.

Journal Article PloS one · January 2024 The relationship between misophonia, stress, and traumatic stress has not been well characterized scientifically. This study aimed to explore the relationships among misophonia, stress, lifetime traumatic events, and traumatic stress. A community sample of ... Full text Cite

Investigation of Thermal Perception and Emotional Response in Augmented Reality using Digital Biomarkers: A Pilot Study

Conference Proceedings - 2023 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops, VRW 2023 · January 1, 2023 Dialectical behavior therapy (DBT) is an evidence-based psychotherapy that helps patients learn skills to regulate emotions as a central strategy to improve life functioning. However, DBT skills require a long-term and consistent commitment, typically to g ... Full text Cite

The unified protocol for transdiagnostic treatment of emotional disorders for misophonia: a pilot trial exploring acceptability and efficacy.

Journal Article Front Psychol · 2023 INTRODUCTION: Misophonia is a recently defined disorder characterized by distressing responses to everyday sounds, such as chewing or sniffling. Individuals with misophonia experience significant functional impairment but have limited options for evidenced ... Full text Link to item Cite

When does modifying the protocol go too far? Considerations for implementing evidence-based treatment in practice.

Journal Article Am Psychol · October 2022 The majority of evidence-based psychological treatments (EBTs) are packaged as manuals that provide guidance regarding when and how to deliver specific interventions (e.g., cognitive restructuring, exposure). However, clinical practice regularly necessitat ... Full text Link to item Cite

Psychiatric and audiologic features of misophonia: Use of a clinical control group with auditory over-responsivity.

Journal Article J Psychosom Res · May 2022 OBJECTIVE: This cross-sectional study was designed to add to the emerging empirical literature characterizing the psychiatric and audiologic features of misophonia. Because most research to date has not compared misophonia to clinical control groups, the p ... Full text Link to item Cite

Adaptation of the TEAM Mental Healthcare Delivery Model: A Mixed-Methods Evaluation.

Journal Article Issues Ment Health Nurs · March 2022 We report on the adaptation and evaluation of an existing approach to multicultural education into an eight-session online, modular curriculum for psychiatric mental health nurse practitioner students (n = 6) and psychology interns (n = 10). Training parti ... Full text Link to item Cite

Development and psychometric exploration of a semi-structured clinical interview for Misophonia

Journal Article Personality and Individual Differences · March 1, 2022 Misophonia is a newly described disorder associated with significant emotional distress, functional impairment, and a wide range of mental health problems (e.g., mood, anxiety, and personality disorders). Although recent studies have begun to validate self ... Full text Cite

Data from: COVID-19 Emotion regulation survey study

Dataset · January 27, 2022 The COVID-19 pandemic has affected the lives of people around the world due to changes including job loss, illness, loss of loved ones, financial insecurity, and social distancing. Emerging research suggests this pandemic has also been deleterious on the m ... Full text Cite

Examining emotional functioning in misophonia: The role of affective instability and difficulties with emotion regulation.

Journal Article PLoS One · 2022 Misophonia is a newly described condition characterized by sensory and emotional reactivity (e.g., anxiety, anger, disgust) to repetitive, pattern-based sounds (e.g., throat clearing, chewing, slurping). Individuals with misophonia report significant funct ... Full text Link to item Cite

Consensus Definition of Misophonia: A Delphi Study.

Journal Article Front Neurosci · 2022 Misophonia is a disorder of decreased tolerance to specific sounds or their associated stimuli that has been characterized using different language and methodologies. The absence of a common understanding or foundational definition of misophonia hinders pr ... Full text Link to item Cite

Opening a window into the riddle of misophonia, sensory over-responsiveness, and pain.

Journal Article Front Neurosci · 2022 INTRODUCTION: Misophonia and sensory over-responsiveness (SOR) share physiological and psychological symptoms. While individuals with SOR demonstrate pain perception alterations, these were not explored in misophonia. METHODS: This exploratory study compri ... Full text Link to item Cite

Phenotyping misophonia: Psychiatric disorders and medical health correlates.

Journal Article Frontiers in psychology · January 2022 Misophonia is characterized by decreased tolerance to specific sounds and associated stimuli that causes significant psychological distress and impairment in daily functioning (Swedo et al., 2022). Aversive stimuli (often called "triggers") are commonly re ... Full text Cite

Does context matter in misophonia? A multi-method experimental investigation.

Journal Article Front Neurosci · 2022 INTRODUCTION: Misophonia is a recently defined disorder in which certain aversive repetitive sounds and associated stimuli elicit distressing and impairing affective, behavioral, and physiological responses. The responses in misophonia may be stronger when ... Full text Link to item Cite

A pilot study investigating the efficacy of brief, phone-based, behavioral interventions for burnout in graduate students.

Journal Article J Clin Psychol · December 2021 OBJECTIVE: This pilot study tested the efficacy of two brief, phone-administered, behavioral interventions derived from behavioral activation in reducing burnout among doctoral students. METHODS: Sixty-six doctoral students demonstrating current high burno ... Full text Link to item Cite

Delivering Transdiagnostic Treatment Over Telehealth During the COVID-19 Pandemic: Application of the Unified Protocol.

Journal Article Cogn Behav Pract · November 2021 The COVID-19 pandemic has necessitated an abrupt transition to remote delivery of psychology services at a time when patients and practicing clinicians are experiencing an increase in life stressors (e.g., job loss, social isolation, need to adapt to teleh ... Full text Link to item Cite

The Use of Task Shifting to Improve Treatment Engagement in an Internet-Based Mindfulness Intervention Among Chinese University Students: Randomized Controlled Trial.

Journal Article JMIR Form Res · October 13, 2021 BACKGROUND: Traditional in-person psychotherapies are incapable of addressing global mental health needs. Use of computer-based interventions is one promising solution for closing the gap between the amount of global mental health treatment needed and rece ... Full text Link to item Cite

Mobile device use among inpatients on a psychiatric unit: A preliminary study.

Journal Article Psychiatry Res · March 2021 Few studies have investigated barriers to mobile phone use for health purposes among patients with serious mental illness. In an inpatient psychiatric adult sample, we examined: (a) patterns and perceptions of mobile phone use and (b) the role of psychiatr ... Full text Link to item Cite

Impact of a computerized intervention for high distress intolerance on cannabis use outcomes: A randomized controlled trial.

Journal Article J Subst Abuse Treat · February 2021 OBJECTIVE: Prevalence of regular cannabis use and cannabis use disorder (CUD) have increased in the past two decades, but treatment-seeking is low and extant brief interventions do not target causal risk factors implicated in etiological models of addictio ... Full text Link to item Cite

An experimental examination of neurostimulation and cognitive restructuring as potential components for Misophonia interventions.

Journal Article J Affect Disord · April 1, 2024 Misophonia is a disorder of decreased tolerance to certain aversive, repetitive common sounds, or to stimuli associated with these sounds. Two matched groups of adults (29 participants with misophonia and 30 clinical controls with high emotion dysregulatio ... Full text Link to item Cite

Misophonia is related to stress but not directly with traumatic stress.

Journal Article PloS one · January 2024 The relationship between misophonia, stress, and traumatic stress has not been well characterized scientifically. This study aimed to explore the relationships among misophonia, stress, lifetime traumatic events, and traumatic stress. A community sample of ... Full text Cite

Investigation of Thermal Perception and Emotional Response in Augmented Reality using Digital Biomarkers: A Pilot Study

Conference Proceedings - 2023 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops, VRW 2023 · January 1, 2023 Dialectical behavior therapy (DBT) is an evidence-based psychotherapy that helps patients learn skills to regulate emotions as a central strategy to improve life functioning. However, DBT skills require a long-term and consistent commitment, typically to g ... Full text Cite

The unified protocol for transdiagnostic treatment of emotional disorders for misophonia: a pilot trial exploring acceptability and efficacy.

Journal Article Front Psychol · 2023 INTRODUCTION: Misophonia is a recently defined disorder characterized by distressing responses to everyday sounds, such as chewing or sniffling. Individuals with misophonia experience significant functional impairment but have limited options for evidenced ... Full text Link to item Cite

When does modifying the protocol go too far? Considerations for implementing evidence-based treatment in practice.

Journal Article Am Psychol · October 2022 The majority of evidence-based psychological treatments (EBTs) are packaged as manuals that provide guidance regarding when and how to deliver specific interventions (e.g., cognitive restructuring, exposure). However, clinical practice regularly necessitat ... Full text Link to item Cite

Psychiatric and audiologic features of misophonia: Use of a clinical control group with auditory over-responsivity.

Journal Article J Psychosom Res · May 2022 OBJECTIVE: This cross-sectional study was designed to add to the emerging empirical literature characterizing the psychiatric and audiologic features of misophonia. Because most research to date has not compared misophonia to clinical control groups, the p ... Full text Link to item Cite

Adaptation of the TEAM Mental Healthcare Delivery Model: A Mixed-Methods Evaluation.

Journal Article Issues Ment Health Nurs · March 2022 We report on the adaptation and evaluation of an existing approach to multicultural education into an eight-session online, modular curriculum for psychiatric mental health nurse practitioner students (n = 6) and psychology interns (n = 10). Training parti ... Full text Link to item Cite

Development and psychometric exploration of a semi-structured clinical interview for Misophonia

Journal Article Personality and Individual Differences · March 1, 2022 Misophonia is a newly described disorder associated with significant emotional distress, functional impairment, and a wide range of mental health problems (e.g., mood, anxiety, and personality disorders). Although recent studies have begun to validate self ... Full text Cite

Data from: COVID-19 Emotion regulation survey study

Dataset · January 27, 2022 The COVID-19 pandemic has affected the lives of people around the world due to changes including job loss, illness, loss of loved ones, financial insecurity, and social distancing. Emerging research suggests this pandemic has also been deleterious on the m ... Full text Cite

Examining emotional functioning in misophonia: The role of affective instability and difficulties with emotion regulation.

Journal Article PLoS One · 2022 Misophonia is a newly described condition characterized by sensory and emotional reactivity (e.g., anxiety, anger, disgust) to repetitive, pattern-based sounds (e.g., throat clearing, chewing, slurping). Individuals with misophonia report significant funct ... Full text Link to item Cite

Consensus Definition of Misophonia: A Delphi Study.

Journal Article Front Neurosci · 2022 Misophonia is a disorder of decreased tolerance to specific sounds or their associated stimuli that has been characterized using different language and methodologies. The absence of a common understanding or foundational definition of misophonia hinders pr ... Full text Link to item Cite

Opening a window into the riddle of misophonia, sensory over-responsiveness, and pain.

Journal Article Front Neurosci · 2022 INTRODUCTION: Misophonia and sensory over-responsiveness (SOR) share physiological and psychological symptoms. While individuals with SOR demonstrate pain perception alterations, these were not explored in misophonia. METHODS: This exploratory study compri ... Full text Link to item Cite

Phenotyping misophonia: Psychiatric disorders and medical health correlates.

Journal Article Frontiers in psychology · January 2022 Misophonia is characterized by decreased tolerance to specific sounds and associated stimuli that causes significant psychological distress and impairment in daily functioning (Swedo et al., 2022). Aversive stimuli (often called "triggers") are commonly re ... Full text Cite

Does context matter in misophonia? A multi-method experimental investigation.

Journal Article Front Neurosci · 2022 INTRODUCTION: Misophonia is a recently defined disorder in which certain aversive repetitive sounds and associated stimuli elicit distressing and impairing affective, behavioral, and physiological responses. The responses in misophonia may be stronger when ... Full text Link to item Cite

A pilot study investigating the efficacy of brief, phone-based, behavioral interventions for burnout in graduate students.

Journal Article J Clin Psychol · December 2021 OBJECTIVE: This pilot study tested the efficacy of two brief, phone-administered, behavioral interventions derived from behavioral activation in reducing burnout among doctoral students. METHODS: Sixty-six doctoral students demonstrating current high burno ... Full text Link to item Cite

Delivering Transdiagnostic Treatment Over Telehealth During the COVID-19 Pandemic: Application of the Unified Protocol.

Journal Article Cogn Behav Pract · November 2021 The COVID-19 pandemic has necessitated an abrupt transition to remote delivery of psychology services at a time when patients and practicing clinicians are experiencing an increase in life stressors (e.g., job loss, social isolation, need to adapt to teleh ... Full text Link to item Cite

The Use of Task Shifting to Improve Treatment Engagement in an Internet-Based Mindfulness Intervention Among Chinese University Students: Randomized Controlled Trial.

Journal Article JMIR Form Res · October 13, 2021 BACKGROUND: Traditional in-person psychotherapies are incapable of addressing global mental health needs. Use of computer-based interventions is one promising solution for closing the gap between the amount of global mental health treatment needed and rece ... Full text Link to item Cite

Mobile device use among inpatients on a psychiatric unit: A preliminary study.

Journal Article Psychiatry Res · March 2021 Few studies have investigated barriers to mobile phone use for health purposes among patients with serious mental illness. In an inpatient psychiatric adult sample, we examined: (a) patterns and perceptions of mobile phone use and (b) the role of psychiatr ... Full text Link to item Cite

Impact of a computerized intervention for high distress intolerance on cannabis use outcomes: A randomized controlled trial.

Journal Article J Subst Abuse Treat · February 2021 OBJECTIVE: Prevalence of regular cannabis use and cannabis use disorder (CUD) have increased in the past two decades, but treatment-seeking is low and extant brief interventions do not target causal risk factors implicated in etiological models of addictio ... Full text Link to item Cite

Development and Initial Validation of the Duke Misophonia Questionnaire.

Journal Article Front Psychol · 2021 Misophonia is characterized by decreased tolerance and accompanying defensive motivational system responding to certain aversive sounds and contextual cues associated with such stimuli, typically repetitive oral (e. g., eating sounds) or nasal (e.g., breat ... Full text Link to item Cite

Emotion regulation difficulties and borderline personality disorder: The moderating role of race.

Journal Article Personal Disord · July 2020 Borderline personality disorder (BPD) is a disorder characterized by emotion regulation (ER) difficulties. Although research indicates that patterns of ER differ across racial groups, few studies have examined the role of race in the ER-BPD association. Th ... Full text Link to item Cite

Cognitive and Behavioral Approaches

Chapter · February 29, 2020 This Handbook provides both breadth and depth regarding current approaches to the understanding, assessment, and treatment of personality disorders. ... Cite

The Mediating Role of Emotion Regulation Within the Relationship Between Neuroticism and Misophonia: A Preliminary Investigation.

Journal Article Front Psychiatry · 2020 Misophonia is a newly described condition characterized by heightened emotional reactivity (e.g., anger, anxiety, and disgust) to common repetitive sounds (e.g., oral or nasal sounds made by others), accompanied by difficulties responding to these sounds ( ... Full text Open Access Link to item Cite

A Preliminary Investigation of the Association Between Misophonia and Symptoms of Psychopathology and Personality Disorders.

Journal Article Front Psychol · 2020 Misophonia is a condition characterized by defensive motivational system emotional responding to repetitive and personally relevant sounds (e.g., eating, sniffing). Preliminary research suggests misophonia may be associated with a range of psychiatric diso ... Full text Open Access Link to item Cite

Acceptability and perceived effectiveness of approaches to support biomedical doctoral student wellness: One size doesn⇔t fit all

Journal Article International Journal of Doctoral Studies · January 1, 2020 Aim/Purpose National and international survey studies have begun to identify heightened levels of depression, anxiety, and burnout among doctoral students. Nevertheless, little research has been done to evaluate which interventions may support doctoral stu ... Full text Cite

Applying the Stress Process Model to Stress-Burnout and Stress-Depression Relationships in Biomedical Doctoral Students: A Cross-Sectional Pilot Study.

Journal Article CBE Life Sci Educ · December 2019 Although doctoral students in the biomedical sciences have been recognized as a population at particular risk for mental health problems such as burnout and depression, little research has been conducted to identify candidate targets for intervention. To t ... Full text Link to item Cite

Burnout and Mental Health Problems in Biomedical Doctoral Students.

Journal Article CBE Life Sci Educ · June 2019 Although burnout and mental health problems may adversely impact quality of scientific research, academic productivity, and attrition in biomedical doctoral training programs, very little research has been done on this topic. Recent studies have used brief ... Full text Link to item Cite

The Effect of Patient Education on Chinese Adolescent and Parental Beliefs About Counselors' Breaches of Confidentiality.

Journal Article J Behav Health Serv Res · April 2019 The primary aim of the present study is to explore whether brief education can change Chinese adolescents' and parents' beliefs about when counselors would breach confidentiality. The two secondary aims are to examine whether the brief education (1) increa ... Full text Link to item Cite

A Path From Childhood Sensory Processing Disorder to Anxiety Disorders: The Mediating Role of Emotion Dysregulation and Adult Sensory Processing Disorder Symptoms.

Journal Article Front Integr Neurosci · 2019 Although maladaptive sensory processing has been observed among individuals with persistent heightened anxiety, it is unclear if difficulties processing sensory input early in life lead to anxiety disorders in adulthood and what mechanisms would drive this ... Full text Open Access Link to item Cite

Blinded by our emotions: The impact of borderline personality disorder and affect on emotion recognition sensitivity

Journal Article Journal of Experimental Psychopathology · January 1, 2019 Previous studies have demonstrated abnormalities in emotion recognition within individuals diagnosed with borderline personality disorder (BPD). However, it is yet unknown how much these abnormalities can be attributed to emotional states or affect. Theref ... Full text Cite

The Surgical Personality: Does Surgery Resident Motivation Predict Attrition?

Journal Article J Am Coll Surg · May 2018 BACKGROUND: There is limited understanding of the wide variation in attrition rates among general surgery residencies. We used the validated Behavior Inhibitory System/Behavior Approach System (BIS/BAS) instrument to compare motivational traits among resid ... Full text Link to item Cite

Suicidal Behavior and Problems with Emotion Regulation.

Journal Article Suicide Life Threat Behav · February 2018 We examined in two independent samples whether: (1) difficulties with emotion regulation predict suicide ideation and (2) depressed adults with a history of attempting suicide report and exhibit more emotion dysregulation compared to healthy and depressed ... Full text Link to item Cite

Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda.

Journal Article Front Neurosci · 2018 Misophonia is a neurobehavioral syndrome phenotypically characterized by heightened autonomic nervous system arousal and negative emotional reactivity (e. g., irritation, anger, anxiety) in response to a decreased tolerance for specific sounds. The aims of ... Full text Link to item Cite

Emotion Regulation in Borderline Personality Disorder: An Experimental Investigation of the Effects of Instructed Acceptance and Suppression.

Journal Article Behav Ther · November 2017 Difficulties with emotion regulation are central to borderline personality disorder (BPD). Recent research suggests that avoidance of emotions in general, and emotion suppression specifically, may be commonly used among those who meet criteria for the diso ... Full text Link to item Cite

The Myth of the Surgical Personality: Motivation and Attrition from Surgical Training

Conference Journal of the American College of Surgeons · October 2017 Full text Cite

Understanding borderline personality disorder across sociocultural groups: Findings, issues, and future directions

Journal Article Current Psychiatry Reviews · September 1, 2017 Background: In recent years, there have been significant advancements in understanding the etiology, assessment, and treatment of borderline personality disorder [BPD]. However, the influence of culture has not been carefully considered. The present review ... Full text Cite

Borderline Personality Disorder and the Effects of Instructed Emotional Avoidance or Acceptance in Daily Life.

Journal Article J Pers Disord · August 2017 This study examined the effects of avoidance- versus acceptance-oriented emotion regulation instructions among individuals with borderline personality disorder (BPD; n = 48), major depressive disorder (MDD; n = 54), and non-psychiatric controls (NPC; n = 5 ... Full text Link to item Cite

REMOVED: Investigating misophonia: A review of the literature, clinical implications and research agenda reflecting current neuroscience and emotion research perspectives.

Conference Eur Psychiatry · April 2017 This article has been removed: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been removed at the request of the authors due to errors in the author list. ... Full text Link to item Cite

Emotional Reactivity to Personally-Relevant and Standardized Sounds in Borderline Personality Disorder

Journal Article Cognitive Therapy and Research · June 1, 2016 Theoretical conceptualizations highlight emotional reactivity as a core problem for borderline personality disorder (BPD); however, empirical work investigating emotional reactivity in BPD has produced mixed and inconclusive findings. The current study aim ... Full text Cite

Perceptions of the Limitations of Confidentiality Among Chinese Mental Health Practitioners, Adolescents and Their Parents

Journal Article Ethics and Behavior · May 18, 2016 The present study aims to (a) survey Chinese mental health professionals’ attitudes toward therapeutic confidentiality with adolescent patients in specific clinical situations, and (b) compare Chinese adolescents’ and parents’ beliefs about when most menta ... Full text Cite

A Virtual Joy-Stick Study of Emotional Responses and Social Motivation in Children with Autism Spectrum Disorder.

Journal Article J Autism Dev Disord · December 2015 A new virtual reality task was employed which uses preference for interpersonal distance to social stimuli to examine social motivation and emotion perception in children with Autism Spectrum Disorders. Nineteen high function children with higher functioni ... Full text Link to item Cite

Non-suicidal self-injury with and without borderline personality disorder: differences in self-injury and diagnostic comorbidity.

Journal Article Psychiatry Res · November 30, 2015 Although non-suicidal self-injury (NSSI) occurs in people with and without borderline personality disorder (BPD), few studies have compared the clinical characteristics of these two groups. The present study sampled adults with a history of NSSI and compar ... Full text Link to item Cite

Ambulatory measurement of emotional dysfunction in borderline personality disorder

Journal Article Current Opinion in Psychology · June 1, 2015 Empirical research has used many methods and measures to study emotional dysfunction in borderline personality disorder (BPD) in controlled laboratory settings. Equally important, however, is the need to use externally valid laboratory and field methods to ... Full text Cite

Identity disturbance and problems with emotion regulation are related constructs across diagnoses.

Journal Article J Clin Psychol · April 2015 OBJECTIVE: This study examined the relation between identity disturbance and emotion dysregulation in a cross-diagnostic sample. We assessed whether these constructs are related and relevant beyond borderline personality disorder (BPD). METHOD: We recruite ... Full text Link to item Cite

Interpersonal assessment of borderline personality disorder: preliminary findings.

Journal Article J Pers Assess · 2015 We examined the reliability and validity of scores on an interpersonal measure of borderline personality disorder (BPD). Ratings on the Interpersonal Measure of Borderline Personality Disorder (IM-B) were based on nonverbal behaviors and interpersonal inte ... Full text Link to item Cite

A Preliminary Examination of the Role of Emotion Differentiation in the Relationship between Borderline Personality and Urges for Maladaptive Behaviors.

Journal Article J Psychopathol Behav Assess · December 2014 BACKGROUND AND OBJECTIVES: Impulsive, maladaptive, and potentially self-damaging behaviors are a hallmark feature of borderline personality (BP) pathology. Difficulties with emotion regulation have been implicated in both BP pathology and maladaptive behav ... Full text Link to item Cite

Translation of associative learning models into extinction reminders delivered via mobile phones during cue exposure interventions for substance use.

Journal Article Psychol Addict Behav · September 2014 Despite experimental findings and some treatment research supporting the use of cues as a means to induce and extinguish cravings, interventions using cue exposure have not been well integrated into contemporary substance abuse treatments. A primary proble ... Full text Link to item Cite

Interpersonal functioning in borderline personality disorder: a systematic review of behavioral and laboratory-based assessments.

Journal Article Clin Psychol Rev · April 2014 It is widely accepted that interpersonal problems are a central area of difficulty for those with borderline personality disorder (BPD). However, empirical elucidation of the specific behaviors, or patterns of behaviors, characterizing interpersonal dysfun ... Full text Link to item Cite

Effects of virtual environment platforms on emotional responses.

Journal Article Comput Methods Programs Biomed · March 2014 The goal of the current study was to investigate the effects of different virtual environment (VE) technologies (i.e., desktop, head mounted display, or fully immersive platforms) on emotional arousal and task performance. Fifty-three participants were rec ... Full text Link to item Cite

Meclizine enhancement of sensorimotor gating in healthy male subjects with high startle responses and low prepulse inhibition.

Journal Article Neuropsychopharmacology · February 2014 Histamine H1 receptor systems have been shown in animal studies to have important roles in the reversal of sensorimotor gating deficits, as measured by prepulse inhibition (PPI). H1-antagonist treatment attenuates the PPI impairments caused by either block ... Full text Link to item Cite

Difficulties with emotion regulation mediate the relationship between borderline personality disorder symptom severity and interpersonal problems.

Journal Article Personal Ment Health · August 2013 Problems with interpersonal functioning and difficulties with emotion regulation are core characteristics of borderline personality disorder (BPD). Little is known, however, about the interrelationship between these areas of dysfunction in accounting for B ... Full text Link to item Cite

Negative interpersonal events mediate the relation between borderline features and aggressive behavior: findings from a nonclinical sample of undergraduate women.

Journal Article Personal Disord · July 2013 Interpersonal dysfunction and aggression are features that are frequently found in individuals with borderline personality disorder (BPD); however, few studies have examined the possible causal relationship between aggressive actions and interpersonal prob ... Full text Link to item Cite

Comparison of checking behavior in adults with or without checking symptom of obsessive-compulsive disorder using a novel computer-based measure.

Journal Article Comput Methods Programs Biomed · October 2012 Easy to administer behavioral measures of checking are needed to improve the assessment of this hallmark feature of OCD. We recently developed a new computer-based behavioral assessment of OCD in a previous study. As a follow-up experiment for this method, ... Full text Link to item Cite

Comparison of desktop, head mounted display, and six wall fully immersive systems using a stressful task

Conference Proceedings - IEEE Virtual Reality · May 14, 2012 The goal of the current study was to investigate the effects of different virtual environment (VE) technologies on emotional arousal and task performance in a modified Stroop task presented under low- and high-stress conditions. Fifty-three participants we ... Full text Cite

Effects of unexpected changes in visual scenes on the human acoustic startle response and prepulse inhibition.

Journal Article Behav Processes · January 2012 Prepulse inhibition (PPI) refers to the process wherein startle responses to salient stimuli (e.g., startling sound pulses) are attenuated by the presentation of another stimulus (e.g., a brief pre-pulse) immediately before the startling stimulus. Accordin ... Full text Link to item Cite

Speed and accuracy of facial expression classification in avoidant personality disorder: a preliminary study.

Journal Article Personal Disord · October 2011 The aim of this preliminary study was to examine whether individuals with avoidant personality disorder (APD) could be characterized by deficits in the classification of dynamically presented facial emotional expressions. Using a community sample of adults ... Full text Link to item Cite

Reactivity to sensations in borderline personality disorder: a preliminary study.

Journal Article J Pers Disord · October 2011 Individuals with borderline personality disorder (BPD) are widely considered to have problems with emotional reactivity. However, the specific kinds of stimuli that are associated with heightened emotional reactivity in BPD have not been well characterized ... Full text Link to item Cite

Dialectical behavior therapy

Chapter · 2011 Dialectical behavior therapy (DBT) is an approach to behavior therapy that is distinctive in its attention to, and intentional use of, dialectical processes of polarization, tension, and synthesis in its understanding of client and therapist behavioral pat ... Full text Cite

An experimental investigation of emotional reactivity and delayed emotional recovery in borderline personality disorder: the role of shame.

Journal Article Compr Psychiatry · 2010 Despite the emphasis on emotional reactivity and delayed emotional recovery in prominent theoretical accounts of borderline personality disorder (BPD), research in this area remains limited. This study sought to extend extant research by examining emotiona ... Full text Link to item Cite

Development of a computer-based behavioral assessment of checking behavior in obsessive-compulsive disorder.

Journal Article Compr Psychiatry · 2010 OBJECTIVE: The goal of the current study was to develop and obtain preliminary psychometric data for a computer-based behavioral measure of compulsive checking behavior in a sample of patients with obsessive-compulsive disorder (OCD). METHOD: We examined p ... Full text Link to item Cite

Experiential avoidance mediates the relationship between sexual victimization and psychological symptoms: Replicating findings with an ethnically diverse sample

Journal Article Cognitive Therapy and Research · October 1, 2009 Studies have found experiential avoidance mediates the relationship between sexual victimization and psychological symptoms; however, this work has been conducted primarily with Caucasian samples. The purpose of this study was to examine whether this model ... Full text Cite

Emotional learning during dissociative states in borderline personality disorder.

Journal Article J Psychiatry Neurosci · May 2009 BACKGROUND: Neurobiological findings and clinical data suggest that dissociative experience inhibits conditioning processes, but experimental studies are lacking. The aim of our study was to determine whether high states of dissociative experience would sp ... Link to item Cite

Emotion suppression in borderline personality disorder: an experience sampling study.

Journal Article J Pers Disord · February 2009 This study examined the effects of suppressing emotions in the natural environment among individuals who were high (high-BPD; n = 30) and low (low-BPD; n = 39) in borderline personality disorder (BPD) features. Participants responded to prompts from a pers ... Full text Link to item Cite

Decision-making and risk aversion among depressive adults.

Journal Article J Behav Ther Exp Psychiatry · December 2008 Depression is associated with behavioral avoidance of potentially rewarding environmental contexts. The present study examined the performance of depressive individuals and controls on a neuropsychological measure of decision-making that favors risk avoida ... Full text Link to item Cite

Prefrontal mechanisms for executive control over emotional distraction are altered in major depression.

Journal Article Psychiatry Res · July 15, 2008 A dysfunction in the interaction between executive function and mood regulation has been proposed as the pathophysiology of depression. However, few studies have investigated the alteration in brain systems related to executive control over emotional distr ... Full text Link to item Cite

Differences in emotional experience and emotion regulation as a function of age and psychiatric condition.

Journal Article Aging Ment Health · July 2008 In this study, self-reported experiences of negative affectivity and emotional regulation in a sample of older and younger adults with and without psychiatric co-morbidity were evaluated. Study participants were divided into four separate groups (younger n ... Full text Link to item Cite

Emotional reactivity to auditory stimuli in borderline personality disorder

Conference INTERNATIONAL JOURNAL OF PSYCHOLOGY · June 1, 2008 Link to item Cite

Distress and affective dysregulation in patients with borderline personality disorder: a psychophysiological ambulatory monitoring study.

Journal Article J Nerv Ment Dis · April 2008 Borderline personality disorder (BPD) is characterized by enduring psychological distress and affective dysregulation. Several models have linked both phenomena, but are lacking empirical support. To investigate the relation between psychological distress ... Full text Link to item Cite

Dialectical behavior therapy: Efficacy, mechanisms, and application

Journal Article Psychiatric Times · February 1, 2008 Cite

Borderline personality disorder and emotional responding: a review of the research literature.

Journal Article Clin Psychol Rev · January 2008 Although problems with emotional functioning are considered central to borderline personality disorder (BPD), it is only recently that studies have begun utilizing laboratory biobehavioral measures (including neuroimaging and psychophysiological measures) ... Full text Link to item Cite

Coping and thought suppression as predictors of suicidal ideation in depressed older adults with personality disorders.

Journal Article Aging Ment Health · January 2008 Suicide rates are higher among older adults than any other age group and suicidal ideation is one of the best predictors of completed suicide in older adults. Despite this, few studies have evaluated predictors of suicidal ideation and other correlates of ... Full text Link to item Cite

Emotion regulation skills mediate the effects of shame on eating disorder symptoms in women.

Journal Article Eat Disord · 2008 We examined the impact of negative affectivity, chronic shame, and emotion regulation skills on eating disorder symptoms in undergraduate women (N = 154). We hypothesized that self-reported emotion regulation skills would mediate the well-documented relati ... Full text Link to item Cite

A mediational model of trait negative affectivity, dispositional thought suppression, and intrusive thoughts following laboratory stressors.

Journal Article Behav Res Ther · April 2007 Two studies examined the relationships among trait negative affectivity, dispositional thought suppression, and intrusions in non-clinical samples. In Study 1 (N=87), participants were presented with a series of emotionally evocative images and intrusions ... Full text Link to item Cite

Risk aversion among depressed older adults with obsessive compulsive personality disorder

Journal Article Cognitive Therapy and Research · April 1, 2007 Despite considerable research on depression in older adults, few studies have included individuals with personality disorders or have used laboratory tasks to examine behavioral correlates of depression among older adults. This study used the Bechara Gambl ... Full text Cite

The effects of sexual assault-related intrusion suppression in the laboratory and natural environment.

Journal Article Behav Res Ther · January 2007 Individuals with a history of sexual victimization often experience enduring intrusive thoughts associated with their assault history. Research suggests that the characteristic ways in which sexually assaulted individuals respond to aversive internal exper ... Full text Link to item Cite

Dialectical behavior therapy for patients dually diagnosed with borderline personality disorder and substance use disorders

Journal Article Psychiatric Times · December 1, 2006 Overall, DBT-SUD is a principle-driven and flexible treatment approach for individuals with BPD and co-occurring SUD that is comprehensive, in that the treatment modalities include: 1) individual therapy to enhance patient motivation and develop strategies ... Cite

Heightened sensitivity to facial expressions of emotion in borderline personality disorder.

Journal Article Emotion · November 2006 Individuals with borderline personality disorder (BPD) have been hypothesized to exhibit significant problems associated with emotional sensitivity. The current study examined emotional sensitivity (i.e., low threshold for recognition of emotional stimuli) ... Full text Link to item Cite

An experimental investigation of emotion dysregulation in borderline personality disorder.

Journal Article J Abnorm Psychol · November 2006 Despite the prominent role of emotion dysregulation in theoretical accounts of borderline personality disorder (BPD), few studies have examined emotion dysregulation in BPD. This study extends extant research by providing an experimental investigation of e ... Full text Link to item Cite

Thought suppression mediates the relationship between negative mood and PTSD in sexually assaulted women.

Journal Article J Trauma Stress · October 2006 Sexually victimized individuals often report chronic attempts to avoid unpleasant internal experiences (e.g., thoughts, emotions, memories) as a means of affect regulation. The aim of this study was to expand upon previous findings by examining the relatio ... Full text Link to item Cite

Self-punishment as a regulation strategy in borderline personality disorder.

Journal Article J Pers Disord · June 2006 Studies using the Thought Control Questionnaire (TCQ; Wells & Davies, 1994) suggest that the tendency to use self-punishment (e.g., shouting at oneself) in order to control unpleasant internal experiences (e.g., cognitive and emotional) is associated with ... Full text Link to item Cite

Mechanisms of change in dialectical behavior therapy: theoretical and empirical observations.

Journal Article J Clin Psychol · April 2006 Dialectical behavior therapy (DBT) can be considered a well-established treatment for borderline personality disorder (BPD) as evidenced by seven well-controlled randomized clinical trials across four independent research teams. The primary purpose of this ... Full text Link to item Cite

Avoidance mediates the relationship between perceived criticism in the family of origin and psychological distress in adulthood

Journal Article Journal of Emotional Abuse · March 30, 2006 This study examined a mediational model whereby avoidance was hypothesized to mediate the relationship between higher perceived criticism in the family of origin and psychological distress in adulthood. Undergraduate women (N = 141) completed self-report i ... Full text Cite

Thought suppression mediates the relationship between negative affect and borderline personality disorder symptoms.

Journal Article Behav Res Ther · September 2005 The purpose of this study was to examine the relationships among negative affect, childhood sexual abuse (CSA), thought suppression, and diagnostic symptoms of borderline personality disorder (BPD) in a community sample (n=127). Findings suggest that the t ... Full text Link to item Cite

Impulsivity as a common process across borderline personality and substance use disorders.

Journal Article Clin Psychol Rev · September 2005 Borderline personality disorder (BPD) is a significant public health problem characterized by persistent problems with emotional, behavioral, cognitive, and interpersonal functioning. Research indicates an especially high rate of comorbidity between BPD an ... Full text Link to item Cite

An analogue investigation of the relationships among perceived parental criticism, negative affect, and borderline personality disorder features: the role of thought suppression.

Journal Article Behav Res Ther · February 2005 The current study examined the relationships among biological predisposition, social environment, emotion regulation, and features characteristic of Borderline Personality Disorder (BPD). Using an analogue sample, we examined whether thought suppression me ... Full text Link to item Cite

Chronic avoidance helps explain the relationship between severity of childhood sexual abuse and psychological distress in adulthood.

Journal Article J Child Sex Abus · 2005 Recent studies have found that chronic avoidance of unpleasant internal experiences (e.g., thoughts, emotions, memories) is a maladaptive means of affect regulation often adopted by women with a history of sexual victimization in childhood. The primary aim ... Full text Link to item Cite

Thought suppression and treatment outcome in late-life depression.

Journal Article Aging Ment Health · January 2005 This study examined severity of depression, age of onset, and thought suppression as predictors of treatment outcome. Measures were taken pre-treatment, post-treatment, and at six-month follow-up in 34 depressed older adults receiving the treatment protoco ... Full text Link to item Cite

A model predicting suicidal ideation and hopelessness in depressed older adults: the impact of emotion inhibition and affect intensity.

Journal Article Aging Ment Health · November 2004 The purpose of this study was to begin a preliminary examination of constructs theorized to be related to suicidal behavior by testing a model of the influence of both temperament and emotion regulation on suicidal ideation and hopelessness in a sample of ... Full text Link to item Cite

Experimental avoidance as a mediator of the effects of adolescent sexual victimization on negative adult outcomes.

Journal Article Violence Vict · February 2004 The study examined experiential avoidance as a mediator between sexual victimization and negative adult outcomes. Baron and Kenny's (1986) regression analyses were performed on a sample of 304 undergraduate women to assess direct and indirect effects of se ... Full text Link to item Cite

Examining the inventory of interpersonal problems as a tool for conducting analogue studies of mechanisms underlying Borderline Personality Disorder.

Journal Article J Behav Ther Exp Psychiatry · 2003 Despite recent advancements in the treatment of Borderline Personality Disorder (BPD), little is known about the underlying mechanisms in the development and maintenance of the disorder. To examine these issues, it is first necessary to identify a brief sc ... Full text Link to item Cite