Current Duke Appointments & Affiliations
Adjunct Associate Professor in the Engineering Graduate and Professional Programs
·
2025 - Present
Engineering Graduate and Professional Programs,
Pratt School of Engineering
Recent Scholarly Works
Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells.
Journal article Traffic (Copenhagen, Denmark) · May 2001 Clathrin adaptor protein AP-1 complex is thought to function in forming clathrin-coated vesicles at the trans-Golgi network (TGN) and mediating transport of cargo between the TGN and endosomes. To study trafficking of AP-1 in living cells, yellow fluoresce ... Full text CiteInteraction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy.
Journal article Current biology : CB · November 2000 The interaction of activated epidermal growth factor receptor (EGFR) with the Src homology 2 (SH2) domain of the growth-factor-receptor binding protein Grb2 initiates signaling through Ras and mitogen-activated protein kinase (MAP kinase) [1,2]. Activation ... Full text CiteInhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis.
Journal article The EMBO journal · May 1999 Although interactions between the mu2 subunit of the clathrin adaptor protein complex AP-2 and tyrosine-based internalization motifs have been implicated in the selective recruitment of cargo molecules into coated pits, the functional significance of this ... Full text CiteEducation
University of Nottingham (United Kingdom) ·
1984
Ph.D.