Journal ArticleTraffic (Copenhagen, Denmark) · May 2001
Clathrin adaptor protein AP-1 complex is thought to function in forming clathrin-coated vesicles at the trans-Golgi network (TGN) and mediating transport of cargo between the TGN and endosomes. To study trafficking of AP-1 in living cells, yellow fluoresce ...
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Journal ArticleCurrent biology : CB · November 2000
The interaction of activated epidermal growth factor receptor (EGFR) with the Src homology 2 (SH2) domain of the growth-factor-receptor binding protein Grb2 initiates signaling through Ras and mitogen-activated protein kinase (MAP kinase) [1,2]. Activation ...
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Journal ArticleThe EMBO journal · May 1999
Although interactions between the mu2 subunit of the clathrin adaptor protein complex AP-2 and tyrosine-based internalization motifs have been implicated in the selective recruitment of cargo molecules into coated pits, the functional significance of this ...
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Journal ArticleThe Journal of biological chemistry · December 1998
A chimera of the epidermal growth factor receptor (EGFR) and green fluorescent protein (GFP) has been engineered by fusing GFP to the carboxyl terminus of EGFR. Data are provided to demonstrate that the GFP moiety does not affect the expected functioning o ...
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Journal ArticleScience (New York, N.Y.) · August 1998
Eps15 homology (EH) domains are eukaryotic signaling modules that recognize proteins containing Asn-Pro-Phe (NPF) sequences. The structure of the central EH domain of Eps15 has been solved by heteronuclear magnetic resonance spectroscopy. The fold consists ...
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Journal ArticleThe Journal of biological chemistry · June 1997
Eps15 is a member of an emerging family of proteins containing a novel protein/protein interaction domain, the EH domain, of as yet unknown function. Recent findings of Eps15 association with clathrin adaptor complex AP-2 and its localization in clathrin-c ...
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Journal ArticleAnimal Behaviour · January 1, 1995
DNA fingerprinting showed that 15% of 62 house martin nestlings at study colonies in central Scotland were not related to their putative fathers, and 32% of 19 broods contained at least one extra-pair chick. There was no evidence of intraspecific brood par ...
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Journal ArticleMolecular ecology · June 1994
Broods of young merlins were compared with the adults in attendance at their nest by DNA fingerprinting. No offspring were found that mismatched genetically suggesting that intraspecific brood parasitism and extrapair fertilization are very rare in this po ...
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Journal ArticleMolecular Ecology · January 1, 1993
The statistical power of the technique of DNA fingerprinting relies greatly on the ability of the investigator to make an assumption that the presence or absence of different fingerprint bands are independent. Such linkage equilibrium is unlikely if bands ...
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Journal ArticleAustralian Journal of Zoology · January 1, 1993
Genetic relationships between adults and nestlings of the short.tailed shearwater, Puffinus tenuirostris, were analysed by multilocus DNA fingerprinting. Short.tailed shearwaters are socially monogamous, forming strong pair bonds, often for many years. The ...
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Journal ArticleHeredity · January 1, 1992
The relationships between 420 Passer domesticus (house sparrow) nestlings from 144 broods and the adults which fed them were determined using genetic markers. The inheritance and independence of six polymorphic enzymes observed with starch gel electrophore ...
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Journal ArticleAquaculture · June 1, 1991
The technique of DNA fingerprinting using human minisatellite probes is applied to the study of gynogenetically derived fish in two tilapia species, Oreochromis aureus and O. niloticus. In O. aureus, analysis of the progeny of a cross between two putative ...
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Journal ArticleHeredity · January 1, 1990
The genetic variation in three species of swans was examined by DNA fingerprinting. Human minisatellite probes detected a number of highly variable fragments in the restriction digests of total nuclear DNA. Assuming bands to be independent, the average all ...
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Journal ArticleNature · May 1987
Over the past twenty years, several techniques from biochemical and molecular genetics, such as enzyme electrophoresis and isoelectric focusing, have been widely and successfully applied to the study of population differentiation and evolution. However, th ...
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