Journal ArticleJ Hosp Med · August 2025
INTRODUCTION: Gram-negative bacteremia (GNB) is associated with significant morbidity and mortality. Transition to oral therapy has traditionally utilized fluoroquinolones or trimethoprim-sulfamethoxazole rather than beta-lactams due to concerns about phar ...
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Journal ArticleJ Grad Med Educ · June 2025
Background The Choosing Wisely campaign recommends that clinicians avoid repetitive laboratory testing in hospitalized patients who have clinical and laboratory stability; however, it is unclear how physicians define laboratory stability, or how they adher ...
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Journal ArticleTelemed J E Health · June 2024
Introduction: Although therapeutic inertia is a known driver of suboptimal type 2 diabetes control, little is known about how to combat this phenomenon. We analyzed randomized trial data to determine whether a comprehensive telehealth intervention was more ...
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Journal ArticleJ Endocr Soc · December 1, 2021
Individuals with type 2 diabetes (T2DM) are at high risk for nonalcoholic fatty liver disease (NAFLD), and evidence suggests that poor glycemic control is linked to heightened risk of progressive NAFLD. We conducted an observational study based on data fro ...
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Journal ArticleJournal of the Intensive Care Society · August 2019
Objective To determine the effect of Normosol™-R as compared to normal saline on the outcomes of acute kidney injury and the need for renal replacement therapy in the resuscitation phase of sepsis.
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Journal ArticlePLoS One · 2018
The RV144 Phase III clinical trial with ALVAC-HIV prime and AIDSVAX B/E subtypes CRF01_AE (A244) and B (MN) gp120 boost vaccine regime in Thailand provided a foundation for the future development of improved vaccine strategies that may afford protection ag ...
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Journal ArticleJ Immunol · February 1, 2017
In the RV144 gp120 HIV vaccine trial, decreased transmission risk was correlated with Abs that reacted with a linear epitope at a lysine residue at position 169 (K169) in the HIV-1 envelope (Env) V2 region. The K169 V2 response was restricted to Abs bearin ...
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Journal ArticleJ Virol · May 15, 2016
UNLABELLED: Maternal vaccination to induce anti-HIV immune factors in breast milk is a potential intervention to prevent postnatal HIV-1 mother-to-child transmission (MTCT). We previously demonstrated that immunization of lactating rhesus monkeys with a mo ...
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Journal ArticleJ Virol · August 2015
To evaluate antibody specificities induced by simian immunodeficiency virus (SIV) versus human immunodeficiency virus type 1 (HIV-1) envelope antigens in nonhuman primate (NHP), we profiled binding antibody responses to linear epitopes in NHP studies with ...
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Journal ArticlePLoS Pathog · August 2015
HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protective, t ...
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Journal ArticleThe Electronic Library · April 1, 1996
The Los Angeles Dodgers have a World Wide Web site. On its face, this news may not strike you as particularly significant, especially if you're not a fan of the predominantly New World (cum Asian‐Pacific) sport of baseball. But for this observer of ...
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