Sairam V. Jabba | Scholars@Duke

Sairam V. Jabba
Research Associate, Senior

Current Appointments & Affiliations

Research Associate, Senior, Anesthesiology, Clinical Science Departments

Contact Information

3 Genome Court #6200 MSRB3, Durham, NC 27710
sairam.jabba@duke.edu +1 919 684 1319
Sairam Jabba Linkedin

Recognition
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Anesthetic and synthetic cooling flavors in E-cigarettes: Chemistry and respiratory effects modulating nicotine intake awarded by National Institutes of Health 2018 - 2021
- Cellular Toxicity of Novel Flavor-Solvent Adducts in Electronic Cigarettes awarded by Yale University 2019 - 2020
- Project 1: Effects of Flavors on Nicotine Choice and Central Reward Me awarded by Yale University 2013 - 2020
- Project 1: Effects of Flavors on Nicotine Choice and Central Reward Me awarded by Yale University 2014 - 2018
- Mechanisms of Itch in Poison Ivy-Induced Allergic Contact Dermatitis awarded by National Institutes of Health 2016 - 2018
- Targeting Injury Pathways to Counteract Pulmonary Agent and Vesicant Toxicity awarded by National Institutes of Health 2014 - 2018
- CARRYOVER Request - Irritant Flavor Products in Heated E-Cigarette Liquids and Vapors awarded by Yale University 2015 - 2017
- Irritant Flavor Products in Heated E-Cigarette Liquids and Vapors awarded by Yale University 2015 - 2016
Fellowships, Supported Research, & Other Grants
- Cellular Toxicity of Novel Flavor-Solvent Adducts in Electronic Cigarettes awarded by US FDA & Yale TCORS 2019 - 2020
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Jabba, S. V., & Jordt, S.-E. (2019). Risk Analysis for the Carcinogen Pulegone in Mint- and Menthol-Flavored e-Cigarettes and Smokeless Tobacco Products. Jama Intern Med. https://doi.org/10.1001/jamainternmed.2019.3649
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  - Erythropel, H. C., Jabba, S. V., DeWinter, T. M., Mendizabal, M., Anastas, P. T., Jordt, S. E., & Zimmerman, J. B. (2019). Formation of flavorant-propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids. Nicotine Tob Res, 21(9), 1248–1258. https://doi.org/10.1093/ntr/nty192
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  - Jordt, S.-E., & Jabba, S. (2019). Tobacco industry's investment in sweetness comes full circle. Bmj, 365, l2338. https://doi.org/10.1136/bmj.l2338
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  - Jordt, S. E., & Jabba, S. (2019). Sweeteners are added to modify consumer behaviour. Bmj, 364, l366. https://doi.org/10.1136/bmj.l366
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  - Caceres, A. I., Liu, B., Jabba, S. V., Achanta, S., Morris, J. B., & Jordt, S.-E. (2017). Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti-inflammatory effects of eucalyptol. Br J Pharmacol, 174(9), 867–879. https://doi.org/10.1111/bph.13760
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  - Fan, L., Balakrishna, S., Jabba, S. V., Bonner, P. E., Taylor, S. R., Picciotto, M. R., & Jordt, S.-E. (2016). Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism. Tob Control, 25(Suppl 2), ii50–ii54. https://doi.org/10.1136/tobaccocontrol-2016-053209
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  - Fan, L., Balakrishna, S., Jabba, S. V., Bonner, P. E., Taylor, S. R., Picciotto, M. R., & Jordt, S. E. (2016). Menthol decreases oral nicotine aversion in C57BL/6 mice through a TRPM8-dependent mechanism. Tobacco Control. https://doi.org/10.1136/annrheumdis-2016-053209
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  - Jabba, S., Goyal, R., Sosa-Pagán, J. O., Moldenhauer, H., Wu, J., Kalmeta, B., … Grandl, J. (2014). Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six. Neuron, 82(5), 1017–1031. https://doi.org/10.1016/j.neuron.2014.04.016
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  - Li, H., Bowling, J. J., Fronczek, F. R., Hong, J., Jabba, S. V., Murray, T. F., … Jung, J. H. (2013). Asteropsin A: an unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx. Biochimica Et Biophysica Acta, 1830(3), 2591–2599. https://doi.org/10.1016/j.bbagen.2012.11.015
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  - Nunnery, J. K., Engene, N., Byrum, T., Cao, Z., Jabba, S. V., Pereira, A. R., … Gerwick, W. H. (2012). Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria. The Journal of Organic Chemistry, 77(9), 4198–4208. https://doi.org/10.1021/jo300160e
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  - Jabba, S. V., Prakash, A., Dravid, S. M., Gerwick, W. H., & Murray, T. F. (2010). Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels. The Journal of Pharmacology and Experimental Therapeutics, 332(3), 698–709. https://doi.org/10.1124/jpet.109.161802
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  - George, J., Dravid, S. M., Prakash, A., Xie, J., Peterson, J., Jabba, S. V., … Murray, T. F. (2009). Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 29(10), 3288–3301. https://doi.org/10.1523/jneurosci.6104-08.2009
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  - Jabba, S. V., Oelke, A., Singh, R., Maganti, R. J., Fleming, S., Wall, S. M., … Wangemann, P. (2006). Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model. Bmc Medicine, 4, 37. https://doi.org/10.1186/1741-7015-4-37
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  - Singh, R., Maganti, R. J., Jabba, S. V., Wang, M., Deng, G., Heath, J. D., … Wangemann, P. (2005). Microarray-based comparison of three amplification methods for nanogram amounts of total RNA. American Journal of Physiology. Cell Physiology, 288(5), C1179–C1189. https://doi.org/10.1152/ajpcell.00258.2004
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  - Wangemann, P., Itza, E. M., Albrecht, B., Wu, T., Jabba, S. V., Maganti, R. J., … Marcus, D. C. (2004). Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model. Bmc Medicine, 2, 30. https://doi.org/10.1186/1741-7015-2-30
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Awards & Honors

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

Selected Publications

Academic Articles