Sandeep S. Dave
Professor of Medicine
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2017
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2007
Contact Information
- 101 Science Drive, CIEMAS 2177C, Box 3382, Durham, NC 27710
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sandeep.dave@duke.edu
(919) 681-1922
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Website
- Background
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Education, Training, & Certifications
- Fellow in Hematology-Oncology, Medicine, National Institutes of Health 2001 - 2007
- Medical Resident, Medicine, Northwestern University 1999 - 2001
- M.D., Northwestern University 1999
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Hematological Malignancies, Medicine 2013 - 2017
- Associate Professor of Medicine, Medicine, Hematological Malignancies, Medicine 2012 - 2013
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2007 - 2012
- Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2007
- Recognition
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In the News
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JUL 20, 2021 School of Medicine Magnify -
OCT 6, 2017 Duke Health News -
AUG 20, 2013
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- Expertise
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Global Scholarship
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Research
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- Research
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Selected Grants
- Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Core C: Molecular and Pathology Assessment Core awarded by Dana-Farber Cancer Institute 2021 - 2022
- Targeting Histone Methylation in PTCL awarded by Dana-Farber Cancer Institute 2021 - 2022
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Genetic and genomic signatures of long-term radiation exposure in non-human primates awarded by Wake Forest University School Of Medicine 2015 - 2021
- Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2021
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Understanding the context-dependent roles of mutations in lymphoma awarded by National Institutes of Health 2015 - 2021
- Understanding the Context-Dependent Roles of Mutations in Lymphoma awarded by National Institutes of Health 2009 - 2020
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- The Tumor Suppressive Role of ID3 in Burkitt Lymphoma awarded by Lymphoma Research Foundation of America 2018 - 2020
- Stimulate Research in HIV/AIDS Cancer Research Projects at NCI-designated Cancer Centers awarded by National Institutes of Health 2015 - 2019
- AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease awarded by National Institutes of Health 2018 - 2019
- Phase 1 Trial of Panobinostat + Ruxolitnib for Relapsed/Refactory Diffused Large B Cell Lymphoma (DLBCL) awarded by Lymphoma Research Foundation of America 2016 - 2019
- Genomic Predictors of Response in Mantle Cell Lymphoma awarded by Lymphoma Research Foundation of America 2018 - 2019
- Dissecting mechanism(s) by which ionizing radiation promotes clonal expansion of premalignant cells in the thymus awarded by National Institutes of Health 2016 - 2018
- Dissecting the role of injury is sarcoma formation awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2017
- Dissecting the role of injury is sarcoma formation awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2017
- HARDAC+:Reproducible HPC for next-generation genomics awarded by North Carolina Biotechnology Center 2016 - 2017
- The genetics of hepatosplenic T cell lymphoma awarded by National Institutes of Health 2015 - 2017
- Genetic determinants of progression in chronic lymphocytic leukemia awarded by V Foundation for Cancer Research 2012 - 2016
- Novel combinations to overcome resistance to histone deacetylase inhibitors in lymphoma awarded by Leukemia & Lymphoma Society 2015 - 2016
- Predicting Treatment Futility in Refractory Diffuse Large B cell Lymphoma awarded by Leukemia & Lymphoma Society 2014 - 2015
- Clinico-Genomic Assessment of Performance Status in Elderly AML Patients awarded by National Institutes of Health 2012 - 2015
- Exome-wide screening for common mutations in lymphoma awarded by National Institutes of Health 2011 - 2013
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External Relationships
- Data Driven Bioscience
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Bonglack, Emmanuela N., Joshua E. Messinger, Jana M. Cable, James Ch’ng, K Mark Parnell, Nicolás M. Reinoso-Vizcaíno, Ashley P. Barry, et al. “Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas.” Proc Natl Acad Sci U S A 118, no. 25 (June 22, 2021). https://doi.org/10.1073/pnas.2022495118.Full Text Link to Item
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Holkova, Beata, Danielle Shafer, Victor Yazbeck, Sandeep Dave, Prithviraj Bose, Mary Beth Tombes, Ellen Shrader, et al. “Phase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome.” Leuk Lymphoma 62, no. 5 (May 2021): 1187–94. https://doi.org/10.1080/10428194.2020.1861270.Full Text Link to Item
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Shingleton, Jennifer, Jie Wang, Carolyn Baloh, Tushar Dave, Nicholas Davis, Lanie Happ, Othmane Jadi, et al. “Non-Hodgkin Lymphomas: Malignancies Arising from Mature B Cells.” Cold Spring Harb Perspect Med 11, no. 3 (March 1, 2021). https://doi.org/10.1101/cshperspect.a034843.Full Text Link to Item
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Ravi, Dashnamoorthy, Afshin Beheshti, Nasséra Abermil, Frederick Lansigan, William Kinlaw, Nirupa R. Matthan, Maisarah Mokhtar, et al. “Oncogenic Integration of Nucleotide Metabolism via Fatty Acid Synthase in Non-Hodgkin Lymphoma.” Front Oncol 11 (2021): 725137. https://doi.org/10.3389/fonc.2021.725137.Full Text Link to Item
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Lee, Michelle J., Jean L. Koff, Jeffrey M. Switchenko, C Ileen Jhaney, R Andrew Harkins, Sharvil P. Patel, Sandeep S. Dave, and Christopher R. Flowers. “Genome-defined African ancestry is associated with distinct mutations and worse survival in patients with diffuse large B-cell lymphoma.” Cancer 126, no. 15 (August 1, 2020): 3493–3503. https://doi.org/10.1002/cncr.32866.Full Text Link to Item
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Fedoriw, Yuri, Sara Selitsky, Nathan D. Montgomery, Sviatoslav M. Kendall, Kristy L. Richards, Wei Du, Tamiwe Tomoka, et al. “Identifying transcriptional profiles and evaluating prognostic biomarkers of HIV-associated diffuse large B-cell lymphoma from Malawi.” Mod Pathol 33, no. 8 (August 2020): 1482–91. https://doi.org/10.1038/s41379-020-0506-3.Full Text Link to Item
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Shingleton, Jennifer R., and Sandeep S. Dave. “Polatuzumab Vedotin: Honing in on Relapsed or Refractory Diffuse Large B-Cell Lymphoma.” J Clin Oncol 38, no. 2 (January 10, 2020): 166–68. https://doi.org/10.1200/JCO.19.02587.Full Text Link to Item
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Li, Xiang, Rachel Kositsky, Anupama Reddy, Cassandra Love, Kikkeri Naresh, Jean L. Koff, Ilja Nystrand, et al. “Whole Exome and Transcriptome Sequencing in 1042 Cases Reveals Distinct Clinically Relevant Genetic Subgroups of Follicular Lymphoma.” Blood 134, no. Supplement_1 (November 13, 2019): 19. https://doi.org/10.1182/blood-2019-130255.Full Text Link to Item
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Panea, Razvan I., Cassandra L. Love, Jennifer R. Shingleton, Anupama Reddy, Jeffrey A. Bailey, Ann M. Moormann, Juliana A. Otieno, et al. “The whole-genome landscape of Burkitt lymphoma subtypes.” Blood 134, no. 19 (November 7, 2019): 1598–1607. https://doi.org/10.1182/blood.2019001880.Full Text Link to Item
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Elbaek, Mette Vestergaard, Mette Ølgod Pedersen, Marie Fredslund Breinholt, Anupama Reddy, Cassandra Love, Erik Clasen-Linde, Helle Knudsen, et al. “PD-L1 expression is low in large B-cell lymphoma with MYC or double-hit translocation.” Hematol Oncol 37, no. 4 (October 2019): 375–82. https://doi.org/10.1002/hon.2664.Full Text Link to Item
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Shingleton, Jennifer R., and Sandeep S. Dave. “TET2 Deficiency Sets the Stage for B-cell Lymphoma.” Cancer Discov 8, no. 12 (December 2018): 1515–17. https://doi.org/10.1158/2159-8290.CD-18-1143.Full Text Link to Item
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Van Mater, David, Eric Xu, Anupama Reddy, Leonor Añó, Mohit Sachdeva, Wesley Huang, Nerissa Williams, et al. “Injury promotes sarcoma development in a genetically and temporally restricted manner.” Jci Insight 3, no. 20 (October 18, 2018). https://doi.org/10.1172/jci.insight.123687.Full Text Link to Item
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Manzano, Mark, Ajinkya Patil, Alexander Waldrop, Sandeep S. Dave, Amir Behdad, and Eva Gottwein. “Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma.” Nat Commun 9, no. 1 (August 15, 2018): 3263. https://doi.org/10.1038/s41467-018-05506-9.Full Text Link to Item
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Shingleton, Jennifer R., and Sandeep S. Dave. “Genetic convergence of rare lymphomas.” Curr Opin Hematol 25, no. 4 (July 2018): 307–14. https://doi.org/10.1097/MOH.0000000000000435.Full Text Link to Item
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Posfai, Dora, Kayla Sylvester, Anupama Reddy, Jack G. Ganley, Johannes Wirth, Quinlan E. Cullen, Tushar Dave, Nobutaka Kato, Sandeep S. Dave, and Emily R. Derbyshire. “Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.” Plos Pathog 14, no. 5 (May 2018): e1007057. https://doi.org/10.1371/journal.ppat.1007057.Full Text Open Access Copy Link to Item
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Roy, Sumedha, Amanda J. Moore, Cassandra Love, Anupama Reddy, Deepthi Rajagopalan, Sandeep S. Dave, Leping Li, Cornelis Murre, and Yuan Zhuang. “Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection.” Front Immunol 9 (2018): 42. https://doi.org/10.3389/fimmu.2018.00042.Full Text Link to Item
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Grossman, Lisa, Chris Chang, Joanne Dai, Pavel A. Nikitin, Dereje D. Jima, Sandeep S. Dave, and Micah A. Luftig. “Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines.” Msphere 2, no. 6 (November 2017). https://doi.org/10.1128/mSphere.00305-17.Full Text Link to Item
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Bouska, Alyssa, Chengfeng Bi, Waseem Lone, Weiwei Zhang, Ambreen Kedwaii, Tayla Heavican, Cynthia M. Lachel, et al. “Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets.” Blood 130, no. 16 (October 19, 2017): 1819–31. https://doi.org/10.1182/blood-2017-02-767335.Full Text Link to Item
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Reddy, Anupama, Jenny Zhang, Nicholas S. Davis, Andrea B. Moffitt, Cassandra L. Love, Alexander Waldrop, Sirpa Leppa, et al. “Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.” Cell 171, no. 2 (October 5, 2017): 481-494.e15. https://doi.org/10.1016/j.cell.2017.09.027.Full Text Link to Item
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Guo, X., J. L. Koff, A. B. Moffitt, M. Cinar, S. Ramachandiran, Z. Chen, J. M. Switchenko, et al. “Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.” Oncogene 36, no. 29 (July 20, 2017): 4224–32. https://doi.org/10.1038/onc.2017.90.Full Text Link to Item
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Huang, Jianguo, Mark Chen, Melodi Javid Whitley, Hsuan-Cheng Kuo, Eric S. Xu, Andrea Walens, Yvonne M. Mowery, et al. “Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.” Nat Commun 8 (July 10, 2017): 15999. https://doi.org/10.1038/ncomms15999.Full Text Link to Item
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Bouchlaka, Myriam N., Andrea B. Moffitt, Jaehyup Kim, John A. Kink, Debra D. Bloom, Cassandra Love, Sandeep Dave, Peiman Hematti, and Christian M. Capitini. “Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models.” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 23, no. 6 (June 2017): 897–905. https://doi.org/10.1016/j.bbmt.2017.02.018.Full Text
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Moffitt, Andrea B., Sarah L. Ondrejka, Matthew McKinney, Rachel E. Rempel, John R. Goodlad, Chun Huat Teh, Sirpa Leppa, et al. “Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.” J Exp Med 214, no. 5 (May 1, 2017): 1371–86. https://doi.org/10.1084/jem.20160894.Full Text Link to Item
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Li, Jia, Sumedha Roy, Young-Mi Kim, Shibo Li, Baojun Zhang, Cassandra Love, Anupama Reddy, et al. “Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors.” J Immunol 198, no. 8 (April 15, 2017): 3136–48. https://doi.org/10.4049/jimmunol.1601935.Full Text Link to Item
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McKinney, Matthew, Andrea B. Moffitt, Philippe Gaulard, Marion Travert, Laurence De Leval, Alina Nicolae, Mark Raffeld, et al. “The Genetic Basis of Hepatosplenic T-cell Lymphoma.” Cancer Discov 7, no. 4 (April 2017): 369–79. https://doi.org/10.1158/2159-8290.CD-16-0330.Full Text Link to Item
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Moffitt, Andrea B., and Sandeep S. Dave. “Clinical Applications of the Genomic Landscape of Aggressive Non-Hodgkin Lymphoma.” J Clin Oncol 35, no. 9 (March 20, 2017): 955–62. https://doi.org/10.1200/JCO.2016.71.7603.Full Text Link to Item
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Healy, Jane A., Adrienne Nugent, Rachel E. Rempel, Andrea B. Moffitt, Nicholas S. Davis, Xiaoyu Jiang, Jennifer R. Shingleton, et al. “GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo.” Blood 127, no. 22 (June 2, 2016): 2723–31. https://doi.org/10.1182/blood-2015-07-659938.Full Text Link to Item
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Doss, Jennifer F., David L. Corcoran, Dereje D. Jima, Marilyn J. Telen, Sandeep S. Dave, and Jen-Tsan Chi. “A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes.” Bmc Genomics 16 (November 16, 2015): 952. https://doi.org/10.1186/s12864-015-2156-2.Full Text Link to Item
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Guo, Xiaoge, Kevin Lehner, Karen O’Connell, Jenny Zhang, Sandeep S. Dave, and Sue Jinks-Robertson. “SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing.” G3 (Bethesda) 5, no. 12 (October 23, 2015): 2801–8. https://doi.org/10.1534/g3.115.023317.Full Text Link to Item
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Healy, Jane A., and Sandeep S. Dave. “The Role of EBV in the Pathogenesis of Diffuse Large B Cell Lymphoma.” Curr Top Microbiol Immunol 390, no. Pt 1 (2015): 315–37. https://doi.org/10.1007/978-3-319-22822-8_13.Full Text Link to Item
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Collie, Angela M. B., Jörk Nölling, Kiran M. Divakar, Jeffrey J. Lin, Paula Carver, Lisa M. Durkin, Brian T. Hill, et al. “Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system.” Br J Haematol 167, no. 2 (October 2014): 281–85. https://doi.org/10.1111/bjh.12983.Full Text Link to Item
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Greenough, Adrienne, and Sandeep S. Dave. “New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing.” Curr Opin Hematol 21, no. 4 (July 2014): 326–32. https://doi.org/10.1097/MOH.0000000000000059.Full Text Link to Item
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Woyach, Jennifer A., Richard R. Furman, Ta-Ming Liu, Hatice Gulcin Ozer, Marc Zapatka, Amy S. Ruppert, Ling Xue, et al. “Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.” N Engl J Med 370, no. 24 (June 12, 2014): 2286–94. https://doi.org/10.1056/NEJMoa1400029.Full Text Link to Item
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Zhang, Jenny, Dereje Jima, Andrea B. Moffitt, Qingquan Liu, Magdalena Czader, Eric D. Hsi, Yuri Fedoriw, et al. “The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.” Blood 123, no. 19 (May 8, 2014): 2988–96. https://doi.org/10.1182/blood-2013-07-517177.Full Text Link to Item
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Dave, Sandeep S. “The polyphony of BACH2.” Blood 123, no. 7 (February 13, 2014): 950. https://doi.org/10.1182/blood-2014-01-542449.Full Text Link to Item
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Papalas, John A., Matthew S. McKinney, Evan Kulbacki, Sandeep S. Dave, and Endi Wang. “Merkel cell carcinoma with partial B-cell blastic immunophenotype: a potential mimic of cutaneous richter transformation in a patient with chronic lymphocytic lymphoma.” Am J Dermatopathol 36, no. 2 (February 2014): 148–52. https://doi.org/10.1097/DAD.0b013e31829ed784.Full Text Link to Item
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Dave, S., and K. Walsh. “Lymphomas” 2 (August 29, 2013): 668–74. https://doi.org/10.1016/B978-0-12-382227-7.00057-4.Full Text
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Richards, Kristy L., Alison A. Motsinger-Reif, Hsiao-Wei Chen, Yuri Fedoriw, Cheng Fan, Dahlia M. Nielsen, George W. Small, et al. “Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL.” Cancer Res 73, no. 16 (August 15, 2013): 5029–39. https://doi.org/10.1158/0008-5472.CAN-12-3546.Full Text Link to Item
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Walsh, Katherine, Matthew S. McKinney, Cassandra Love, Qingquan Liu, Alice Fan, Amee Patel, Jason Smith, Anne Beaven, Dereje D. Jima, and Sandeep S. Dave. “PAK1 mediates resistance to PI3K inhibition in lymphomas.” Clin Cancer Res 19, no. 5 (March 1, 2013): 1106–15. https://doi.org/10.1158/1078-0432.CCR-12-1060.Full Text Link to Item
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Yang, Shuo, Marina G. Damiano, Heng Zhang, Sushant Tripathy, Andrea J. Luthi, Jonathan S. Rink, Andrey V. Ugolkov, et al. “Biomimetic, synthetic HDL nanostructures for lymphoma.” Proc Natl Acad Sci U S A 110, no. 7 (February 12, 2013): 2511–16. https://doi.org/10.1073/pnas.1213657110.Full Text Link to Item
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Zhang, Jenny, Vladimir Grubor, Cassandra L. Love, Anjishnu Banerjee, Kristy L. Richards, Piotr A. Mieczkowski, Cherie Dunphy, et al. “Genetic heterogeneity of diffuse large B-cell lymphoma.” Proc Natl Acad Sci U S A 110, no. 4 (January 22, 2013): 1398–1403. https://doi.org/10.1073/pnas.1205299110.Full Text Link to Item
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Dave, Sandeep S. “Genomic stratification for the treatment of lymphomas.” Hematology Am Soc Hematol Educ Program 2013 (2013): 331–34. https://doi.org/10.1182/asheducation-2013.1.331.Full Text Link to Item
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Love, Cassandra, and Sandeep Dave. “MicroRNA expression profiling using microarrays.” Methods Mol Biol 999 (2013): 285–96. https://doi.org/10.1007/978-1-62703-357-2_21.Full Text Link to Item
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Love, Cassandra, Zhen Sun, Dereje Jima, Guojie Li, Jenny Zhang, Rodney Miles, Kristy L. Richards, et al. “The genetic landscape of mutations in Burkitt lymphoma.” Nat Genet 44, no. 12 (December 2012): 1321–25. https://doi.org/10.1038/ng.2468.Full Text Link to Item
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Price, Alexander M., Jason P. Tourigny, Eleonora Forte, Raul E. Salinas, Sandeep S. Dave, and Micah A. Luftig. “Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation.” J Virol 86, no. 20 (October 2012): 11096–106. https://doi.org/10.1128/JVI.01069-12.Full Text Link to Item
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Forte, Eleonora, Raul E. Salinas, Christina Chang, Ting Zhou, Sarah D. Linnstaedt, Eva Gottwein, Cassandra Jacobs, et al. “The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells.” J Virol 86, no. 12 (June 2012): 6889–98. https://doi.org/10.1128/JVI.07056-11.Full Text Link to Item
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Dave, Sandeep. “Burkitt lymphoma: analysis of the genome.” Clin Adv Hematol Oncol 10, no. 1 (January 2012): 54–55.Link to Item
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Lugar, Patricia L., Cassandra Love, Amrie C. Grammer, Sandeep S. Dave, and Peter E. Lipsky. “Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus.” Plos One 7, no. 9 (2012): e44362. https://doi.org/10.1371/journal.pone.0044362.Full Text Link to Item
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Gottwein, Eva, David L. Corcoran, Neelanjan Mukherjee, Rebecca L. Skalsky, Markus Hafner, Jeffrey D. Nusbaum, Priscilla Shamulailatpam, et al. “Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.” Cell Host Microbe 10, no. 5 (November 17, 2011): 515–26. https://doi.org/10.1016/j.chom.2011.09.012.Full Text Link to Item
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Lanasa, M. C., S. D. Allgood, S. L. Slager, S. S. Dave, C. Love, G. E. Marti, N. E. Kay, et al. “Immunophenotypic and gene expression analysis of monoclonal B-cell lymphocytosis shows biologic characteristics associated with good prognosis CLL.” Leukemia 25, no. 9 (September 2011): 1459–66. https://doi.org/10.1038/leu.2011.117.Full Text Link to Item
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Hartman, Zachary C., Xiao-Yi Yang, Oliver Glass, Gangjun Lei, Takuya Osada, Sandeep S. Dave, Michael A. Morse, Timothy M. Clay, and Herbert K. Lyerly. “HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis.” Cancer Res 71, no. 13 (July 1, 2011): 4380–91. https://doi.org/10.1158/0008-5472.CAN-11-0308.Full Text Link to Item
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Visco, Carlo, Sylvia Hoeller, Jeffrey T. Malik, Zijun Y. Xu-Monette, Michele L. Wiggins, Jessica Liu, Warren G. Sanger, et al. “Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component.” Am J Surg Pathol 35, no. 2 (February 2011): 177–89. https://doi.org/10.1097/PAS.0b013e3182049a9c.Full Text Open Access Copy Link to Item
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Nikitin, Pavel A., Christopher M. Yan, Eleonora Forte, Alessio Bocedi, Jason P. Tourigny, Robert E. White, Martin J. Allday, et al. “An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells.” Cell Host Microbe 8, no. 6 (December 16, 2010): 510–22. https://doi.org/10.1016/j.chom.2010.11.004.Full Text Link to Item
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Jima, Dereje D., Jenny Zhang, Cassandra Jacobs, Kristy L. Richards, Cherie H. Dunphy, William W. L. Choi, Wing Yan Au, et al. “Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.” Blood 116, no. 23 (December 2, 2010): e118–27. https://doi.org/10.1182/blood-2010-05-285403.Full Text Link to Item
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Hartmann, Elena M., Elias Campo, George Wright, Georg Lenz, Itziar Salaverria, Pedro Jares, Wenming Xiao, et al. “Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling.” Blood 116, no. 6 (August 12, 2010): 953–61. https://doi.org/10.1182/blood-2010-01-263806.Full Text Link to Item
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Dave, Sandeep S. “Host factors for risk and survival in lymphoma.” Hematology Am Soc Hematol Educ Program 2010 (2010): 255–58. https://doi.org/10.1182/asheducation-2010.1.255.Full Text Link to Item
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Mozos, Ana, Cristina Royo, Elena Hartmann, Daphne De Jong, Cristina Baró, Alexandra Valera, Kai Fu, et al. “SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.” Haematologica 94, no. 11 (November 2009): 1555–62. https://doi.org/10.3324/haematol.2009.010264.Full Text Link to Item
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Dunleavy, Kieron, Stefania Pittaluga, Myron S. Czuczman, Sandeep S. Dave, George Wright, Nicole Grant, Margaret Shovlin, et al. “Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma.” Blood 113, no. 24 (June 11, 2009): 6069–76. https://doi.org/10.1182/blood-2009-01-199679.Full Text Link to Item
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Zhang, Jenny, Dereje D. Jima, Cassandra Jacobs, Randy Fischer, Eva Gottwein, Grace Huang, Patricia L. Lugar, et al. “Patterns of microRNA expression characterize stages of human B-cell differentiation.” Blood 113, no. 19 (May 7, 2009): 4586–94. https://doi.org/10.1182/blood-2008-09-178186.Full Text Link to Item
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Longo, Nancy S., Patricia L. Lugar, Sule Yavuz, Wen Zhang, Peter H. L. Krijger, Daniel E. Russ, Dereje D. Jima, Sandeep S. Dave, Amrie C. Grammer, and Peter E. Lipsky. “Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.” Blood 113, no. 16 (April 16, 2009): 3706–15. https://doi.org/10.1182/blood-2008-10-183632.Full Text Link to Item
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Lenz, G., G. Wright, S. S. Dave, W. Xiao, J. Powell, H. Zhao, W. Xu, et al. “Stromal gene signatures in large-B-cell lymphomas.” N Engl J Med 359, no. 22 (November 27, 2008): 2313–23. https://doi.org/10.1056/NEJMoa0802885.Full Text Link to Item
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Lenz, Georg, George W. Wright, NC Tolga Emre, Holger Kohlhammer, Sandeep S. Dave, R Eric Davis, Shannon Carty, et al. “Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways.” Proc Natl Acad Sci U S A 105, no. 36 (September 9, 2008): 13520–25. https://doi.org/10.1073/pnas.0804295105.Full Text Link to Item
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Salaverria, Itziar, Andreas Zettl, Silvia Beà, Elena M. Hartmann, Sandeep S. Dave, George W. Wright, Evert-Jan Boerma, et al. “Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma.” Haematologica 93, no. 9 (September 2008): 1327–34. https://doi.org/10.3324/haematol.13071.Full Text Link to Item
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Shaffer, Arthur L., NC Tolga Emre, Laurence Lamy, Vu N. Ngo, George Wright, Wenming Xiao, John Powell, et al. “IRF4 addiction in multiple myeloma.” Nature 454, no. 7201 (July 10, 2008): 226–31. https://doi.org/10.1038/nature07064.Full Text Link to Item
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Dave, Sandeep S. “Follicular lymphoma and the microenvironment.” Blood 111, no. 9 (May 1, 2008): 4427–28. https://doi.org/10.1182/blood-2008-01-134643.Full Text Link to Item
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Lenz, Georg, R Eric Davis, Vu N. Ngo, Lloyd Lam, Thaddeus C. George, George W. Wright, Sandeep S. Dave, et al. “Oncogenic CARD11 mutations in human diffuse large B cell lymphoma.” Science 319, no. 5870 (March 21, 2008): 1676–79. https://doi.org/10.1126/science.1153629.Full Text Link to Item
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Cuadros, M., E. Honrado, M. Zajac, J. Benitez, B. Martinez-Delgado, S. S. Dave, L. M. Staudt, et al. “In reply [2].” Journal of Clinical Oncology 25, no. 30 (October 20, 2007): 4851–52. https://doi.org/10.1200/JCO.2007.13.4858.Full Text
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Annunziata, Christina M., R Eric Davis, Yulia Demchenko, William Bellamy, Ana Gabrea, Fenghuang Zhan, Georg Lenz, et al. “Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.” Cancer Cell 12, no. 2 (August 2007): 115–30. https://doi.org/10.1016/j.ccr.2007.07.004.Full Text Link to Item
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Cuadros, Marta, Sandeep S. Dave, Elaine S. Jaffe, Emiliano Honrado, Roger Milne, Javier Alves, Jose Rodríguez, et al. “Identification of a proliferation signature related to survival in nodal peripheral T-cell lymphomas.” J Clin Oncol 25, no. 22 (August 1, 2007): 3321–29. https://doi.org/10.1200/JCO.2006.09.4474.Full Text Link to Item
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Lenz, Georg, Inga Nagel, Reiner Siebert, Anna V. Roschke, Warren Sanger, George W. Wright, Sandeep S. Dave, et al. “Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma.” J Exp Med 204, no. 3 (March 19, 2007): 633–43. https://doi.org/10.1084/jem.20062041.Full Text Link to Item
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Dave, S. S., and L. M. Staudt. “Drs. Dave and Staudt reply [5].” New England Journal of Medicine 355, no. 10 (September 7, 2006): 1064. https://doi.org/10.1056/NEJMc061833.Full Text
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Dave, Sandeep S. “Gene expression signatures and outcome prediction in mature B-cell malignancies.” Curr Treat Options Oncol 7, no. 4 (July 2006): 261–69. https://doi.org/10.1007/s11864-006-0035-4.Full Text Link to Item
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Dave, Sandeep S., Kai Fu, George W. Wright, Lloyd T. Lam, Philip Kluin, Evert-Jan Boerma, Timothy C. Greiner, et al. “Molecular diagnosis of Burkitt's lymphoma.” N Engl J Med 354, no. 23 (June 8, 2006): 2431–42. https://doi.org/10.1056/NEJMoa055759.Full Text Link to Item
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Ngo, Vu N., R Eric Davis, Laurence Lamy, Xin Yu, Hong Zhao, Georg Lenz, Lloyd T. Lam, et al. “A loss-of-function RNA interference screen for molecular targets in cancer.” Nature 441, no. 7089 (May 4, 2006): 106–10. https://doi.org/10.1038/nature04687.Full Text Link to Item
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Dave, Sandeep. “Gene expression profiling and outcome prediction in non-Hodgkin lymphoma.” Biol Blood Marrow Transplant 12, no. 1 Suppl 1 (January 2006): 50–52. https://doi.org/10.1016/j.bbmt.2005.10.017.Full Text Link to Item
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Fu, Kai, Dennis D. Weisenburger, Timothy C. Greiner, Sandeep Dave, George Wright, Andreas Rosenwald, Michael Chiorazzi, et al. “Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling.” Blood 106, no. 13 (December 15, 2005): 4315–21. https://doi.org/10.1182/blood-2005-04-1753.Full Text Link to Item
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Hong, Wan-Jen, Roger Warnke, and Gilbert Chu. “Immune signatures in follicular lymphoma.” N Engl J Med 352, no. 14 (April 7, 2005): 1496–97.Link to Item
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Gajewski, Thomas F. “Lymphoma-infiltrating immune cells.” N Engl J Med 352, no. 7 (February 17, 2005): 724–25.Link to Item
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Staudt, Louis M., and Sandeep Dave. “The biology of human lymphoid malignancies revealed by gene expression profiling.” Adv Immunol 87 (2005): 163–208. https://doi.org/10.1016/S0065-2776(05)87005-1.Full Text Link to Item
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Dave, Sandeep S., George Wright, Bruce Tan, Andreas Rosenwald, Randy D. Gascoyne, Wing C. Chan, Richard I. Fisher, et al. “Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells.” N Engl J Med 351, no. 21 (November 18, 2004): 2159–69. https://doi.org/10.1056/NEJMoa041869.Full Text Link to Item
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Iqbal, Javeed, Warren G. Sanger, Douglas E. Horsman, Andreas Rosenwald, Diane L. Pickering, Bhavana Dave, Sandeep Dave, et al. “BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma.” Am J Pathol 165, no. 1 (July 2004): 159–66. https://doi.org/10.1016/s0002-9440(10)63284-1.Full Text Link to Item
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Golub, Robert, Jared Adams, Sundeep Dave, and Charles L. Bennett. “Cost-effectiveness considerations in the treatment of essential thrombocythemia.” Semin Oncol 29, no. 3 Suppl 10 (June 2002): 28–32. https://doi.org/10.1053/sonc.2002.33758.Full Text Link to Item
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Juneja, T., M. A. Pericak-Vance, N. G. Laing, S. Dave, and T. Siddique. “Prognosis in familial amyotrophic lateral sclerosis: progression and survival in patients with glu100gly and ala4val mutations in Cu,Zn superoxide dismutase.” Neurology 48, no. 1 (January 1997): 55–57. https://doi.org/10.1212/wnl.48.1.55.Full Text Link to Item
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Dave, S., and D. J. Mogul. “ATP receptor activation potentiates a voltage-dependent Ca channel in hippocampal neurons.” Brain Res 715, no. 1–2 (April 9, 1996): 208–16. https://doi.org/10.1016/0006-8993(95)01588-4.Full Text Link to Item
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Book Sections
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McKinney, M. S., and S. S. Dave. “Origin of Non-Hodgkin Lymphoma.” In Hematology Basic Principles and Practice, edited by R. Hoffman, E. J. Benz, L. E. Silberstein, H. E. Heslop, J. I. Weitz, J. Anastasi, M. E. Salama, and S. A. Abutalib. Elsevier Health Sciences, 2013.
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- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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