Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Hematology-Oncology, Medicine, National Institutes of Health 2001 - 2007
  • Medical Resident, Medicine, Northwestern University 1999 - 2001
  • M.D., Northwestern University 1999
• 

  Duke Appointment History

  • Associate Professor of Medicine, Medicine, Hematological Malignancies, Medicine 2013 - 2017
  • Associate Professor of Medicine, Medicine, Hematological Malignancies, Medicine 2012 - 2013
  • Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2007 - 2012
  • Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2007
• Recognition
• 

  In the News

  • OCT 6, 2017

    Duke Health News

    Researchers Identify Genetic Drivers of Most Common Form of Lymphoma

  • AUG 20, 2013

    Duke Receives $1.3 Million for Immune Deficiency Research
• Expertise
• 

  Global Scholarship

  • Research

    • India (Country) 
• Research
• 

  Selected Grants

  • Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
  • Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
  • Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
  • Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2021
  • Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
  • Genetic and genomic signatures of long-term radiation exposure in non-human primates awarded by Wake Forest University School Of Medicine 2015 - 2020
  • Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
  • Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
  • Defining the Functional Role of Mutations in Diffuse Large B cell Lymphoma awarded by National Institutes of Health 2015 - 2020
  • Administrative Supplements for P30 CCSG awarded by National Institutes of Health 2015 - 2019
  • Understanding the Context-Dependent Roles of Mutations in Lymphoma awarded by National Institutes of Health 2009 - 2019
  • Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2019
  • AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease awarded by National Institutes of Health 2018 - 2019
  • Genomic Predictors of Response in Mantle Cell Lymphoma awarded by Lymphoma Research Foundation of America 2018 - 2019
  • The Tumor Suppressive Role of ID3 in Burkitt Lymphoma awarded by Lymphoma Research Foundation of America 2018 - 2019
  • Phase 1 Trial of Panobinostat + Ruxolitnib for Relapsed/Refactory Diffused Large B Cell Lymphoma (DLBCL) awarded by Lymphoma Research Foundation of America 2016 - 2019
  • Dissecting mechanism(s) by which ionizing radiation promotes clonal expansion of premalignant cells in the thymus awarded by National Institutes of Health 2016 - 2018
  • Dissecting the role of injury is sarcoma formation awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2017
  • Dissecting the role of injury is sarcoma formation awarded by Sarcoma Alliance for Research Through Collaboration 2015 - 2017
  • HARDAC+:Reproducible HPC for next-generation genomics awarded by North Carolina Biotechnology Center 2016 - 2017
  • The genetics of hepatosplenic T cell lymphoma awarded by National Institutes of Health 2015 - 2017
  • Genetic determinants of progression in chronic lymphocytic leukemia awarded by V Foundation for Cancer Research 2012 - 2016
  • Novel combinations to overcome resistance to histone deacetylase inhibitors in lymphoma awarded by Leukemia & Lymphoma Society 2015 - 2016
  • Predicting Treatment Futility in Refractory Diffuse Large B cell Lymphoma awarded by Leukemia & Lymphoma Society 2014 - 2015
  • Clinico-Genomic Assessment of Performance Status in Elderly AML Patients awarded by National Institutes of Health 2012 - 2015
  • Exome-wide screening for common mutations in lymphoma awarded by National Institutes of Health 2011 - 2013
• Publications & Artistic Works
• 

  Selected Publications

  • Journal Articles

    • Manzano, M, Patil, A, Waldrop, A, Dave, SS, Behdad, A, and Gottwein, E. "Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma." Nature Communications 9, no. 1 (August 15, 2018): 3263-null.  Full Text
    • Shingleton, JR, and Dave, SS. "Genetic convergence of rare lymphomas." Current Opinion in Hematology 25, no. 4 (July 2018): 307-314.  Full Text
    • Posfai, D, Sylvester, K, Reddy, A, Ganley, JG, Wirth, J, Cullen, QE, Dave, T, Kato, N, Dave, SS, and Derbyshire, ER. "Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection." Plos Pathogens 14, no. 5 (May 18, 2018): e1007057-null.  Full Text  Open Access Copy
    • Roy, S, Moore, AJ, Love, C, Reddy, A, Rajagopalan, D, Dave, SS, Li, L, Murre, C, and Zhuang, Y. "Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection." Frontiers in Immunology 9 (January 24, 2018): 42-null.  Full Text
    • Grossman, L, Chang, C, Dai, J, Nikitin, PA, Jima, DD, Dave, SS, and Luftig, MA. "Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines." mSphere 2, no. 6 (November 29, 2017).  Full Text
    • Bouska, A, Bi, C, Lone, W, Zhang, W, Kedwaii, A, Heavican, T, Lachel, CM, Yu, J, Ferro, R, Eldorghamy, N, Greiner, TC, Vose, J, Weisenburger, DD, Gascoyne, RD, Rosenwald, A, Ott, G, Campo, E, Rimsza, LM, Jaffe, ES, Braziel, RM, Siebert, R, Miles, RR, Dave, S, Reddy, A, Delabie, J, Staudt, LM, Song, JY, McKeithan, TW, Fu, K, Green, M, Chan, WC, and Iqbal, J. "Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets." Blood 130, no. 16 (October 2017): 1819-1831.  Full Text
    • Reddy, A, Zhang, J, Davis, NS, Moffitt, AB, Love, CL, Waldrop, A, Leppa, S, Pasanen, A, Meriranta, L, Karjalainen-Lindsberg, M-L, Nørgaard, P, Pedersen, M, Gang, AO, Høgdall, E, Heavican, TB, Lone, W, Iqbal, J, Qin, Q, Li, G, Kim, SY, Healy, J, Richards, KL, Fedoriw, Y, Bernal-Mizrachi, L, Koff, JL, Staton, AD, Flowers, CR, Paltiel, O, Goldschmidt, N, Calaminici, M, Clear, A, Gribben, J, Nguyen, E, Czader, MB, Ondrejka, SL, Collie, A, Hsi, ED, Tse, E, Au-Yeung, RKH, Kwong, Y-L, Srivastava, G, Choi, WWL, Evens, AM, Pilichowska, M, Sengar, M, Reddy, N, Li, S, Chadburn, A, Gordon, LI, Jaffe, ES, Levy, S, Rempel, R, Tzeng, T, Happ, LE, Dave, T, Rajagopalan, D, Datta, J, Dunson, DB, and Dave, SS. "Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma." Cell 171, no. 2 (October 2017): 481-494.e15.  Full Text
    • Huang, J, Chen, M, Whitley, MJ, Kuo, H-C, Xu, ES, Walens, A, Mowery, YM, Van Mater, D, Eward, WC, Cardona, DM, Luo, L, Ma, Y, Lopez, OM, Nelson, CE, Robinson-Hamm, JN, Reddy, A, Dave, SS, Gersbach, CA, Dodd, RD, and Kirsch, DG. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature communications 8 (July 10, 2017): 15999-.  Full Text
    • Guo, X, Koff, JL, Moffitt, AB, Cinar, M, Ramachandiran, S, Chen, Z, Switchenko, JM, Mosunjac, M, Neill, SG, Mann, KP, Bagirov, M, Du, Y, Natkunam, Y, Khoury, HJ, Rossi, MR, Harris, W, Flowers, CR, Lossos, IS, Boise, LH, Dave, SS, Kowalski, J, and Bernal-Mizrachi, L. "Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype." Oncogene 36, no. 29 (July 2017): 4224-4232.  Full Text
    • Bouchlaka, MN, Moffitt, AB, Kim, J, Kink, JA, Bloom, DD, Love, C, Dave, S, Hematti, P, and Capitini, CM. "Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 23, no. 6 (June 2017): 897-905.  Full Text
    • Moffitt, AB, Ondrejka, SL, McKinney, M, Rempel, RE, Goodlad, JR, Teh, CH, Leppa, S, Mannisto, S, Kovanen, PE, Tse, E, Au-Yeung, RKH, Kwong, Y-L, Srivastava, G, Iqbal, J, Yu, J, Naresh, K, Villa, D, Gascoyne, RD, Said, J, Czader, MB, Chadburn, A, Richards, KL, Rajagopalan, D, Davis, NS, Smith, EC, Palus, BC, Tzeng, TJ, Healy, JA, Lugar, PL, Datta, J, Love, C, Levy, S, Dunson, DB, Zhuang, Y, Hsi, ED, and Dave, SS. "Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2." The Journal of experimental medicine 214, no. 5 (May 2017): 1371-1386.  Full Text
    • Li, J, Roy, S, Kim, Y-M, Li, S, Zhang, B, Love, C, Reddy, A, Rajagopalan, D, Dave, S, Diehl, AM, and Zhuang, Y. "Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors." Journal of Immunology (Baltimore, Md. : 1950) 198, no. 8 (April 2017): 3136-3148.  Full Text
    • McKinney, M, Moffitt, AB, Gaulard, P, Travert, M, De Leval, L, Nicolae, A, Raffeld, M, Jaffe, ES, Pittaluga, S, Xi, L, Heavican, T, Iqbal, J, Belhadj, K, Delfau-Larue, MH, Fataccioli, V, Czader, MB, Lossos, IS, Chapman-Fredricks, JR, Richards, KL, Fedoriw, Y, Ondrejka, SL, Hsi, ED, Low, L, Weisenburger, D, Chan, WC, Mehta-Shah, N, Horwitz, S, Bernal-Mizrachi, L, Flowers, CR, Beaven, AW, Parihar, M, Baseggio, L, Parrens, M, Moreau, A, Sujobert, P, Pilichowska, M, Evens, AM, Chadburn, A, Au-Yeung, RKH, Srivastava, G, Choi, WWL, Goodlad, JR, Aurer, I, Basic-Kinda, S, Gascoyne, RD, Davis, NS, Li, G, Zhang, J, Rajagopalan, D, Reddy, A, Love, C, Levy, S, Zhuang, Y, Datta, J, Dunson, DB, and Davé, SS. "The Genetic Basis of Hepatosplenic T-cell Lymphoma." Cancer Discovery 7, no. 4 (April 2017): 369-379.  Full Text
    • Moffitt, AB, and Dave, SS. "Clinical Applications of the Genomic Landscape of Aggressive Non-Hodgkin Lymphoma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 35, no. 9 (March 2017): 955-962. (Review)  Full Text
    • Healy, JA, Nugent, A, Rempel, RE, Moffitt, AB, Davis, NS, Jiang, X, Shingleton, JR, Zhang, J, Love, C, Datta, J, McKinney, ME, Tzeng, TJ, Wettschureck, N, Offermanns, S, Walzer, KA, Chi, J-T, Rasheed, SAK, Casey, PJ, Lossos, IS, and Dave, SS. "GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo." Blood 127, no. 22 (June 2016): 2723-2731.  Full Text
    • Guo, X, Lehner, K, O'Connell, K, Zhang, J, Dave, SS, and Jinks-Robertson, S. "SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing." G3 (Bethesda, Md.) 5, no. 12 (October 23, 2015): 2801-2808.  Full Text
    • Doss, JF, Corcoran, DL, Jima, DD, Telen, MJ, Dave, SS, and Chi, J-T. "A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes." Bmc Genomics 16 (January 2015): 952-null.  Full Text
    • Healy, JA, and Dave, SS. "The Role of EBV in the Pathogenesis of Diffuse Large B Cell Lymphoma." Current topics in microbiology and immunology 390, no. Pt 1 (January 2015): 315-337. (Review)  Full Text
    • Collie, AMB, Nölling, J, Divakar, KM, Lin, JJ, Carver, P, Durkin, LM, Hill, BT, Smith, MR, Radivoyevitch, T, Kong, LI, Daly, T, Murugesan, G, Guenther-Johnson, J, Dave, SS, Manilich, EA, and Hsi, ED. "Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex® system." British Journal of Haematology 167, no. 2 (October 2014): 281-285. (Letter)  Full Text
    • Greenough, A, and Dave, SS. "New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing." Current Opinion in Hematology 21, no. 4 (July 2014): 326-332. (Review)  Full Text
    • Greenough, A, and Dave, SS. "New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing." Current Opinion in Hematology 21, no. 4 (July 2014): 326-332.  Full Text
    • Woyach, JA, Furman, RR, Liu, T-M, Ozer, HG, Zapatka, M, Ruppert, AS, Xue, L, Li, DH-H, Steggerda, SM, Versele, M, Dave, SS, Zhang, J, Yilmaz, AS, Jaglowski, SM, Blum, KA, Lozanski, A, Lozanski, G, James, DF, Barrientos, JC, Lichter, P, Stilgenbauer, S, Buggy, JJ, Chang, BY, Johnson, AJ, and Byrd, JC. "Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib." The New England Journal of Medicine 370, no. 24 (June 2014): 2286-2294.  Full Text
    • Zhang, J, Jima, D, Moffitt, AB, Liu, Q, Czader, M, Hsi, ED, Fedoriw, Y, Dunphy, CH, Richards, KL, Gill, JI, Sun, Z, Love, C, Scotland, P, Lock, E, Levy, S, Hsu, DS, Dunson, D, and Dave, SS. "The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells." Blood 123, no. 19 (May 2014): 2988-2996.  Full Text
    • Dave, SS. "The polyphony of BACH2." Blood 123, no. 7 (February 2014): 950-.  Full Text
    • Papalas, JA, McKinney, MS, Kulbacki, E, Dave, SS, and Wang, E. "Merkel cell carcinoma with partial B-cell blastic immunophenotype: a potential mimic of cutaneous richter transformation in a patient with chronic lymphocytic lymphoma." The American Journal of Dermatopathology 36, no. 2 (February 2014): 148-152.  Full Text
    • Collie, AMB, Nölling, J, Divakar, KM, Lin, JJ, Carver, P, Durkin, LM, Hill, BT, Smith, MR, Radivoyevitch, T, Kong, LI, Daly, T, Murugesan, G, Guenther-Johnson, J, Dave, SS, Manilich, EA, and Hsi, ED. "Molecular subtype classification of formalin-fixed, paraffin-embedded diffuse large B-cell lymphoma samples on the ICEPlex ® system." British Journal of Haematology 167, no. 2 (January 1, 2014): 281-285. (Letter)  Full Text
    • Richards, KL, Motsinger-Reif, AA, Chen, H-W, Fedoriw, Y, Fan, C, Nielsen, DM, Small, GW, Thomas, R, Smith, C, Dave, SS, Perou, CM, Breen, M, Borst, LB, and Suter, SE. "Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL." Cancer Research 73, no. 16 (August 2013): 5029-5039.  Full Text
    • Walsh, K, McKinney, MS, Love, C, Liu, Q, Fan, A, Patel, A, Smith, J, Beaven, A, Jima, DD, and Dave, SS. "PAK1 mediates resistance to PI3K inhibition in lymphomas." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 19, no. 5 (March 2013): 1106-1115.  Full Text
    • Yang, S, Damiano, MG, Zhang, H, Tripathy, S, Luthi, AJ, Rink, JS, Ugolkov, AV, Singh, ATK, Dave, SS, Gordon, LI, and Thaxton, CS. "Biomimetic, synthetic HDL nanostructures for lymphoma." Proceedings of the National Academy of Sciences of the United States of America 110, no. 7 (February 2013): 2511-2516.  Full Text
    • Zhang, J, Grubor, V, Love, CL, Banerjee, A, Richards, KL, Mieczkowski, PA, Dunphy, C, Choi, W, Au, WY, Srivastava, G, Lugar, PL, Rizzieri, DA, Lagoo, AS, Bernal-Mizrachi, L, Mann, KP, Flowers, C, Naresh, K, Evens, A, Gordon, LI, Czader, M, Gill, JI, Hsi, ED, Liu, Q, Fan, A, Walsh, K, Jima, D, Smith, LL, Johnson, AJ, Byrd, JC, Luftig, MA, Ni, T, Zhu, J, Chadburn, A, Levy, S, Dunson, D, and Dave, SS. "Genetic heterogeneity of diffuse large B-cell lymphoma." Proceedings of the National Academy of Sciences of the United States of America 110, no. 4 (January 4, 2013): 1398-1403.  Full Text
    • Dave, S, and Walsh, K. "Lymphomas." Genomic and Personalized Medicine 2 (2013): 668-674.  Full Text
    • Dave, SS. "Genomic stratification for the treatment of lymphomas." Hematology Am Soc Hematol Educ Program 2013 (2013): 331-334. (Review)  Full Text  Link to Item
    • Love, C, and Dave, S. "MicroRNA expression profiling using microarrays." Methods in Molecular Biology 999 (2013): 285-296.  Full Text
    • Love, C, Sun, Z, Jima, D, Li, G, Zhang, J, Miles, R, Richards, KL, Dunphy, CH, Choi, WWL, Srivastava, G, Lugar, PL, Rizzieri, DA, Lagoo, AS, Bernal-Mizrachi, L, Mann, KP, Flowers, CR, Naresh, KN, Evens, AM, Chadburn, A, Gordon, LI, Czader, MB, Gill, JI, Hsi, ED, Greenough, A, Moffitt, AB, McKinney, M, Banerjee, A, Grubor, V, Levy, S, Dunson, DB, and Dave, SS. "The genetic landscape of mutations in Burkitt lymphoma." Nature Genetics 44, no. 12 (December 2012): 1321-1325.  Full Text
    • Price, AM, Tourigny, JP, Forte, E, Salinas, RE, Dave, SS, and Luftig, MA. "Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation." Journal of Virology 86, no. 20 (October 2012): 11096-11106.  Full Text
    • Forte, E, Salinas, RE, Chang, C, Zhou, T, Linnstaedt, SD, Gottwein, E, Jacobs, C, Jima, D, Li, Q-J, Dave, SS, and Luftig, MA. "The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells." Journal of Virology 86, no. 12 (June 2012): 6889-6898.  Full Text
    • Dave, S, and O'Brien, S. "Burkitt lymphoma: Analysis of the genome." Clinical Advances in Hematology and Oncology 10, no. 1 (2012): 54-55.
    • Lugar, PL, Love, C, Grammer, AC, Dave, SS, and Lipsky, PE. "Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus." PLoS One 7, no. 9 (2012): e44362-.  Full Text  Link to Item
    • Gottwein, E, Corcoran, DL, Mukherjee, N, Skalsky, RL, Hafner, M, Nusbaum, JD, Shamulailatpam, P, Love, CL, Dave, SS, Tuschl, T, Ohler, U, and Cullen, BR. "Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines." Cell Host & Microbe 10, no. 5 (November 2011): 515-526.  Full Text
    • Lanasa, MC, Allgood, SD, Slager, SL, Dave, SS, Love, C, Marti, GE, Kay, NE, Hanson, CA, Rabe, KG, Achenbach, SJ, Goldin, LR, Camp, NJ, Goodman, BK, Vachon, CM, Spector, LG, Rassenti, LZ, Leis, JF, Gockerman, JP, Strom, SS, Call, TG, Glenn, M, Cerhan, JR, Levesque, MC, Weinberg, JB, and Caporaso, NE. "Immunophenotypic and gene expression analysis of monoclonal B-cell lymphocytosis shows biologic characteristics associated with good prognosis CLL." Leukemia 25, no. 9 (September 2011): 1459-1466.  Full Text  Link to Item
    • Hartman, ZC, Yang, X-Y, Glass, O, Lei, G, Osada, T, Dave, SS, Morse, MA, Clay, TM, and Lyerly, HK. "HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis." Cancer Research 71, no. 13 (July 2011): 4380-4391.  Full Text
    • Visco, C, Hoeller, S, Malik, JT, Xu-Monette, ZY, Wiggins, ML, Liu, J, Sanger, WG, Liu, Z, Chang, J, Ranheim, EA, Gradowski, JF, Serrano, S, Wang, H-Y, Liu, Q, Dave, S, Olsen, B, Gascoyne, RD, Campo, E, Swerdlow, SH, Chan, WC, Tzankov, A, and Young, KH. "Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component." The American Journal of Surgical Pathology 35, no. 2 (February 2011): 177-189.  Full Text
    • Jima, DD, Zhang, J, Jacobs, C, Richards, KL, Dunphy, CH, Choi, WWL, Au, WY, Srivastava, G, Czader, MB, Rizzieri, DA, Lagoo, AS, Lugar, PL, Mann, KP, Flowers, CR, Bernal-Mizrachi, L, Naresh, KN, Evens, AM, Gordon, LI, Luftig, M, Friedman, DR, Weinberg, JB, Thompson, MA, Gill, JI, Liu, Q, How, T, Grubor, V, Gao, Y, Patel, A, Wu, H, Zhu, J, Blobe, GC, Lipsky, PE, Chadburn, A, Dave, SS, and Hematologic Malignancies Research Consortium, . "Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs." Blood 116, no. 23 (December 2, 2010): e118-e127.  Full Text  Link to Item
    • Nikitin, PA, Yan, CM, Forte, E, Bocedi, A, Tourigny, JP, White, RE, Allday, MJ, Patel, A, Dave, SS, Kim, W, Hu, K, Guo, J, Tainter, D, Rusyn, E, and Luftig, MA. "An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells." Cell Host & Microbe 8, no. 6 (December 2010): 510-522.  Full Text
    • Hartmann, EM, Campo, E, Wright, G, Lenz, G, Salaverria, I, Jares, P, Xiao, W, Braziel, RM, Rimsza, LM, Chan, W-C, Weisenburger, DD, Delabie, J, Jaffe, ES, Gascoyne, RD, Dave, SS, Mueller-Hermelink, H-K, Staudt, LM, Ott, G, Beà, S, and Rosenwald, A. "Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling." Blood 116, no. 6 (August 12, 2010): 953-961.  Full Text  Link to Item
    • Dave, SS. "Host factors for risk and survival in lymphoma." Hematology Am Soc Hematol Educ Program 2010 (2010): 255-258. (Review)  Full Text  Link to Item
    • Dunleavy, K, Pittaluga, S, Czuczman, MS, Dave, SS, Wright, G, Grant, N, Shovlin, M, Jaffe, ES, Janik, JE, Staudt, LM, and Wilson, WH. "Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma." Blood 113, no. 24 (June 2009): 6069-6076.  Full Text
    • Zhang, J, Jima, DD, Jacobs, C, Fischer, R, Gottwein, E, Huang, G, Lugar, PL, Lagoo, AS, Rizzieri, DA, Friedman, DR, Weinberg, JB, Lipsky, PE, and Dave, SS. "Patterns of microRNA expression characterize stages of human B-cell differentiation." Blood 113, no. 19 (May 2009): 4586-4594.  Full Text
    • Longo, NS, Lugar, PL, Yavuz, S, Zhang, W, Krijger, PHL, Russ, DE, Jima, DD, Dave, SS, Grammer, AC, and Lipsky, PE. "Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting." Blood 113, no. 16 (April 16, 2009): 3706-3715.  Full Text  Link to Item
    • Mozos, A, Royo, C, Hartmann, E, Jong, DD, Baró, C, Valera, A, Fu, K, Weisenburger, DD, Delabie, J, Chuang, S-S, Jaffe, ES, Ruiz-Marcellan, C, Dave, S, Rimsza, L, Braziel, R, Gascoyne, RD, Solé, F, López-Guillermo, A, Colomer, D, Staudt, LM, Rosenwald, A, Ott, G, Jares, P, and Campo, E. "SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype." Haematologica 94, no. 11 (2009): 1555-1562.  Full Text
    • Lenz, G, Wright, G, Dave, SS, Xiao, W, Powell, J, Zhao, H, Xu, W, Tan, B, Goldschmidt, N, Iqbal, J, Vose, J, Bast, M, Fu, K, Weisenburger, DD, Greiner, TC, Armitage, JO, Kyle, A, May, L, Gascoyne, RD, Connors, JM, Troen, G, Holte, H, Kvaloy, S, Dierickx, D, Verhoef, G, Delabie, J, Smeland, EB, Jares, P, Martinez, A, Lopez-Guillermo, A, Montserrat, E, Campo, E, Braziel, RM, Miller, TP, Rimsza, LM, Cook, JR, Pohlman, B, Sweetenham, J, Tubbs, RR, Fisher, RI, Hartmann, E, Rosenwald, A, Ott, G, Muller-Hermelink, H-K, Wrench, D, Lister, TA, Jaffe, ES, Wilson, WH, Chan, WC, Staudt, LM, and Lymphoma/Leukemia Molecular Profiling Project, . "Stromal gene signatures in large-B-cell lymphomas." The New England Journal of Medicine 359, no. 22 (November 2008): 2313-2323.  Full Text
    • Lenz, G, Wright, GW, Emre, NCT, Kohlhammer, H, Dave, SS, Davis, RE, Carty, S, Lam, LT, Shaffer, AL, Xiao, W, Powell, J, Rosenwald, A, Ott, G, Muller-Hermelink, HK, Gascoyne, RD, Connors, JM, Campo, E, Jaffe, ES, Delabie, J, Smeland, EB, Rimsza, LM, Fisher, RI, Weisenburger, DD, Chan, WC, and Staudt, LM. "Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways." Proceedings of the National Academy of Sciences of the United States of America 105, no. 36 (September 2, 2008): 13520-13525.  Full Text
    • Salaverria, I, Zettl, A, Beà, S, Hartmann, EM, Dave, SS, Wright, GW, Boerma, E-J, Kluin, PM, Ott, G, Chan, WC, Weisenburger, DD, Lopez-Guillermo, A, Gascoyne, RD, Delabie, J, Rimsza, LM, Braziel, RM, Jaffe, ES, Staudt, LM, Müller-Hermelink, HK, Campo, E, Rosenwald, A, and Leukemia and Lymphoma Molecular Profiling Project (LLMPP), . "Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma." Haematologica 93, no. 9 (September 2008): 1327-1334.  Full Text  Link to Item
    • Shaffer, AL, Emre, NCT, Lamy, L, Ngo, VN, Wright, G, Xiao, W, Powell, J, Dave, S, Yu, X, Zhao, H, Zeng, Y, Chen, B, Epstein, J, and Staudt, LM. "IRF4 addiction in multiple myeloma." Nature 454, no. 7201 (July 2008): 226-231.  Full Text
    • Dave, SS. "Follicular lymphoma and the microenvironment." Blood 111, no. 9 (May 1, 2008): 4427-4428.  Full Text  Link to Item
    • Lenz, G, Davis, RE, Ngo, VN, Lam, L, George, TC, Wright, GW, Dave, SS, Zhao, H, Xu, W, Rosenwald, A, Ott, G, Muller-Hermelink, HK, Gascoyne, RD, Connors, JM, Rimsza, LM, Campo, E, Jaffe, ES, Delabie, J, Smeland, EB, Fisher, RI, Chan, WC, and Staudt, LM. "Oncogenic CARD11 mutations in human diffuse large B cell lymphoma." Science (New York, N.Y.) 319, no. 5870 (March 6, 2008): 1676-1679.  Full Text
    • Cuadros, M, Honrado, E, Zajac, M, Benitez, J, Martinez-Delgado, B, Dave, SS, Staudt, LM, Jaffe, ES, Milne, R, Alves, J, and Rodríguez, J. "In Reply." Journal of Clinical Oncology 25, no. 30 (October 20, 2007): 4851-4852.  Full Text
    • Annunziata, CM, Davis, RE, Demchenko, Y, Bellamy, W, Gabrea, A, Zhan, F, Lenz, G, Hanamura, I, Wright, G, Xiao, W, Dave, S, Hurt, EM, Tan, B, Zhao, H, Stephens, O, Santra, M, Williams, DR, Dang, L, Barlogie, B, Shaughnessy, JD, Kuehl, WM, and Staudt, LM. "Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma." Cancer Cell 12, no. 2 (August 2007): 115-130.  Full Text
    • Cuadros, M, Dave, SS, Jaffe, ES, Honrado, E, Milne, R, Alves, J, Rodríguez, J, Zajac, M, Benitez, J, Staudt, LM, and Martinez-Delgado, B. "Identification of a proliferation signature related to survival in nodal peripheral T-cell lymphomas." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 25, no. 22 (August 2007): 3321-3329.  Full Text
    • Lenz, G, Nagel, I, Siebert, R, Roschke, AV, Sanger, W, Wright, GW, Dave, SS, Tan, B, Zhao, H, Rosenwald, A, Muller-Hermelink, HK, Gascoyne, RD, Campo, E, Jaffe, ES, Smeland, EB, Fisher, RI, Kuehl, WM, Chan, WC, and Staudt, LM. "Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma." The Journal of Experimental Medicine 204, no. 3 (March 12, 2007): 633-643.  Full Text
    • Dave, SS. "Gene expression signatures and outcome prediction in mature B-cell malignancies." Curr Treat Options Oncol 7, no. 4 (July 2006): 261-269. (Review)  Link to Item
    • Dave, SS, Fu, K, Wright, GW, Lam, LT, Kluin, P, Boerma, E-J, Greiner, TC, Weisenburger, DD, Rosenwald, A, Ott, G, Müller-Hermelink, H-K, Gascoyne, RD, Delabie, J, Rimsza, LM, Braziel, RM, Grogan, TM, Campo, E, Jaffe, ES, Dave, BJ, Sanger, W, Bast, M, Vose, JM, Armitage, JO, Connors, JM, Smeland, EB, Kvaloy, S, Holte, H, Fisher, RI, Miller, TP, Montserrat, E, Wilson, WH, Bahl, M, Zhao, H, Yang, L, Powell, J, Simon, R, Chan, WC, Staudt, LM, and Lymphoma/Leukemia Molecular Profiling Project, . "Molecular diagnosis of Burkitt's lymphoma." The New England Journal of Medicine 354, no. 23 (June 2006): 2431-2442.  Full Text
    • Ngo, VN, Davis, RE, Lamy, L, Yu, X, Zhao, H, Lenz, G, Lam, LT, Dave, S, Yang, L, Powell, J, and Staudt, LM. "A loss-of-function RNA interference screen for molecular targets in cancer." Nature 441, no. 7089 (May 2006): 106-110.  Full Text
    • Dave, S. "Gene expression profiling and outcome prediction in non-Hodgkin lymphoma." Biology of Blood and Marrow Transplantation 12, no. SUPPL. 1 (2006): 50-52.  Full Text
    • Dave, SS, and Staudt, LM. "Drs. Dave and Staudt reply [5]." New England Journal of Medicine 355, no. 10 (2006): 1064--.  Full Text
    • Fu, K, Weisenburger, DD, Greiner, TC, Dave, S, Wright, G, Rosenwald, A, Chiorazzi, M, Iqbal, J, Gesk, S, Siebert, R, De Jong, D, Jaffe, ES, Wilson, WH, Delabie, J, Ott, G, Dave, BJ, Sanger, WG, Smith, LM, Rimsza, L, Braziel, RM, Müller-Hermelink, HK, Campo, E, Gascoyne, RD, Staudt, LM, Chan, WC, and Lymphoma/Leukemia Molecular Profiling Project, . "Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling." Blood 106, no. 13 (December 2005): 4315-4321.  Full Text
    • Hong, W-J, Warnke, R, and Chu, G. "Immune signatures in follicular lymphoma." The New England Journal of Medicine 352, no. 14 (April 2005): 1496-1497. (Letter)  Full Text
    • Kobayashi, K, Murashige, N, Jr, YK, Naresh, KN, Gajewski, TF, Dave, SS, and Staudt, LM. "Lymphoma-infiltrating immune cells [1] (multiple letters)." New England Journal of Medicine 352, no. 7 (2005): 724-725.  Full Text
    • Staudt, LM, and Dave, S. "The biology of human lymphoid malignancies revealed by gene expression profiling." Advances in Immunology 87 (January 2005): 163-208. (Review)  Full Text
    • Dave, SS, Wright, G, Tan, B, Rosenwald, A, Gascoyne, RD, Chan, WC, Fisher, RI, Braziel, RM, Rimsza, LM, Grogan, TM, Miller, TP, LeBlanc, M, Greiner, TC, Weisenburger, DD, Lynch, JC, Vose, J, Armitage, JO, Smeland, EB, Kvaloy, S, Holte, H, Delabie, J, Connors, JM, Lansdorp, PM, Ouyang, Q, Lister, TA, Davies, AJ, Norton, AJ, Muller-Hermelink, HK, Ott, G, Campo, E, Montserrat, E, Wilson, WH, Jaffe, ES, Simon, R, Yang, L, Powell, J, Zhao, H, Goldschmidt, N, Chiorazzi, M, and Staudt, LM. "Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells." The New England Journal of Medicine 351, no. 21 (November 2004): 2159-2169.  Full Text
    • Iqbal, J, Sanger, WG, Horsman, DE, Rosenwald, A, Pickering, DL, Dave, B, Dave, S, Xiao, L, Cao, K, Zhu, Q, Sherman, S, Hans, CP, Weisenburger, DD, Greiner, TC, Gascoyne, RD, Ott, G, Müller-Hermelink, HK, Delabie, J, Braziel, RM, Jaffe, ES, Campo, E, Lynch, JC, Connors, JM, Vose, JM, Armitage, JO, Grogan, TM, Staudt, LM, and Chan, WC. "BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma." The American Journal of Pathology 165, no. 1 (July 2004): 159-166.  Full Text
    • Golub, R, Adams, J, Dave, S, and Bennett, CL. "Cost-effectiveness considerations in the treatment of essential thrombocythemia." Seminars in oncology 29, no. 3 Suppl 10 (June 2002): 28-32.  Full Text
    • Juneja, T, Pericak-Vance, MA, Laing, NG, Dave, S, and Siddique, T. "Prognosis in familial amyotrophic lateral sclerosis: progression and survival in patients with glu100gly and ala4val mutations in Cu,Zn superoxide dismutase." Neurology 48, no. 1 (January 1997): 55-57.  Link to Item
    • Dave, S, and Mogul, DJ. "ATP receptor activation potentiates a voltage-dependent Ca channel in hippocampal neurons." Brain Research 715, no. 1-2 (1996): 208-216.  Full Text
• Scholarly, Clinical, & Service Activities
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  Outreach & Engaged Scholarship

  • The molecular landscape of lymphoma on the Indian sub-continent. December 2012  2012

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