Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Jawaharlal Nehru University (India) 2007
• Expertise
• 

  Subject Headings

  • B cells
  • Complement
  • Immunoglobulin M
• Research
• 

  Selected Grants

  • Complement and CR2/CD21 in the Immune Pathogenesis of HIT awarded by National Institutes of Health 2018 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Duarte, Madelaine, Maragatha Kuchibhatla, Sanjay Khandelwal, Gowthami M. Arepally, and Grace M. Lee. “Heterogeneity in neutrophil responses to immune complexes..” Blood Adv 3, no. 19 (October 8, 2019): 2778–89. https://doi.org/10.1182/bloodadvances.2019000235.
       Full Text  Link to Item
    • Khandelwal, Sanjay, Joann Ravi, Lubica Rauova, Alexandra Johnson, Grace M. Lee, Jennifer B. Gilner, Sreenivasulu Gunti, et al. “Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway..” Blood 132, no. 23 (December 6, 2018): 2431–40. https://doi.org/10.1182/blood-2018-03-834598.
       Full Text  Link to Item
    • Khandelwal, Sanjay, Alexandra M. Johnson, Jian Liu, David Keire, Cynthia Sommers, Joann Ravi, Grace M. Lee, John D. Lambris, Edimara S. Reis, and Gowthami M. Arepally. “Novel Immunoassay for Complement Activation by PF4/Heparin Complexes..” Thromb Haemost 118, no. 8 (August 2018): 1484–87. https://doi.org/10.1055/s-0038-1660858.
       Full Text  Link to Item
    • Lee, Grace M., Manali Joglekar, Maragatha Kuchibhatla, Sanjay Khandelwal, Rui Qi, Lubica Rauova, and Gowthami M. Arepally. “Serologic characterization of anti-protamine/heparin and anti-PF4/heparin antibodies..” Blood Adv 1, no. 11 (April 25, 2017): 644–51. https://doi.org/10.1182/bloodadvances.2017004408.
       Full Text  Link to Item
    • Cines, Douglas B., Serge V. Yarovoi, Sergei V. Zaitsev, Tatiana Lebedeva, Lubica Rauova, Mortimer Poncz, Gowthami M. Arepally, et al. “Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia..” Blood Adv 1, no. 1 (November 29, 2016): 62–74. https://doi.org/10.1182/bloodadvances.2016000877.
       Full Text  Link to Item
    • Khandelwal, Sanjay, and Gowthami M. Arepally. “Immune pathogenesis of heparin-induced thrombocytopenia..” Thromb Haemost 116, no. 5 (October 28, 2016): 792–98. https://doi.org/10.1160/TH16-01-0074.
       Full Text  Link to Item
    • Khandelwal, Sanjay, Grace M. Lee, C Garren Hester, Mortimer Poncz, Steven E. McKenzie, Bruce S. Sachais, Lubica Rauova, et al. “The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21)..” Blood 128, no. 14 (October 6, 2016): 1789–99. https://doi.org/10.1182/blood-2016-04-709634.
       Full Text  Link to Item
    • Joglekar, M., S. Khandelwal, D. B. Cines, M. Poncz, L. Rauova, and G. M. Arepally. “Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages..” J Thromb Haemost 13, no. 8 (August 2015): 1416–27. https://doi.org/10.1111/jth.13003.
       Full Text  Link to Item
    • Banerjee, Rajdeep, Sanjay Khandelwal, Yukiko Kozakai, Bikash Sahu, and Sanjai Kumar. “CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite..” Proceedings of the National Academy of Sciences of the United States of America 112, no. 10 (March 2015): 3062–67. https://doi.org/10.1073/pnas.1418144112.
       Full Text
    • Bosch, Berta, Adam C. Berger, Sanjay Khandelwal, Erica L. Heipertz, Brian Scharf, Laura Santambrogio, and Paul A. Roche. “Disruption of Multivesicular Body Vesicles Does Not Affect Major Histocompatibility Complex (MHC) Class II-Peptide Complex Formation and Antigen Presentation by Dendritic Cells.” Journal of Biological Chemistry 288, no. 34 (August 23, 2013): 24286–92. https://doi.org/10.1074/jbc.m113.461996.
       Full Text
    • Saxena, Rajiv K., Nitin Bhardwaj, Sumedha Sachar, Niti Puri, and Sanjay Khandelwal. “A Double in vivo Biotinylation Technique for Objective Assessment of Aging and Clearance of Mouse Erythrocytes in Blood Circulation.” Transfusion Medicine and Hemotherapy 39, no. 5 (2012): 335–41. https://doi.org/10.1159/000342524.
       Full Text
    • Khandelwal, Sanjay, and Paul A. Roche. “Distinct MHC Class II Molecules Are Associated on the Dendritic Cell Surface in Cholesterol-dependent Membrane Microdomains.” Journal of Biological Chemistry 285, no. 46 (November 12, 2010): 35303–10. https://doi.org/10.1074/jbc.m110.147793.
       Full Text
    • Khandelwal, Sanjay, and Rajiv K. Saxena. “A role of phosphatidylserine externalization in clearance of erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte in mice.” Experimental Gerontology 43, no. 8 (August 2008): 764–70. https://doi.org/10.1016/j.exger.2008.05.002.
       Full Text
    • Khandelwal, Sanjay, and Rajiv K. Saxena. “Erratum to: Age-dependent increase in green autofluorescence of blood erythrocytes.” Journal of Biosciences 32, no. S3 (December 2007): 1345–1345. https://doi.org/10.1007/s12038-007-0144-7.
       Full Text
    • Khandelwal, Sanjay, Nico van Rooijen, and Rajiv K. Saxena. “Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation.” Transfusion 47, no. 9 (September 2007): 1725–32. https://doi.org/10.1111/j.1537-2995.2007.01348.x.
       Full Text
    • Khandelwal, Sanjay, and Rajiv K. Saxena. “Assessment of survival of aging erythrocyte in circulation and attendant changes in size and CD147 expression by a novel two step biotinylation method.” Experimental Gerontology 41, no. 9 (September 2006): 855–61. https://doi.org/10.1016/j.exger.2006.06.045.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.