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Sanjay Khandelwal

Assistant Professor in Medicine
Medicine, Hematology
Room 371, Alex H Sands Building, Research Drive, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor in Medicine · 2021 - Present Medicine, Hematology, Medicine

Recent Publications


Complement activation as a biomarker for platelet-activating antibodies in heparin-induced thrombocytopenia.

Journal Article J Thromb Haemost · March 2025 BACKGROUND: Immunoglobulin G antibodies (Abs) to platelet factor 4 (PF4) complexed to heparin (PF4/H) commonly occur after H exposure but cause life-threatening complications of H-induced thrombocytopenia (HIT) in only a few patients. Presently, only plate ... Full text Link to item Cite

Platelet and red cell responses to three North American pit vipers.

Journal Article Toxicon · August 28, 2024 We investigated the hemotoxic effects of three North American pit vipers in healthy human donor blood. Using experiments focusing on platelet and red blood cell activity, we found differential effects of these venoms on these cellular components. Platelet ... Full text Link to item Cite

Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs.

Journal Article J Immunol · February 15, 2024 The classical pathway (CP) is a potent mechanism for initiating complement activity and is a driver of pathology in many complement-mediated diseases. The CP is initiated via activation of complement component C1, which consists of the pattern recognition ... Full text Link to item Cite
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Recent Grants


Complement activating properties of anti-Sm/RNP antibodies in SLE

ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2026

Comparative studies of complement responses to ICs

ResearchResearch Associate · Awarded by National Institutes of Health · 2023 - 2025

Complement and Thrombosis in HIT

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 2020 - 2024

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Education, Training & Certifications


Jawaharlal Nehru University (India) · 2007 Ph.D.