Current Appointments & Affiliations
Assistant Professor in Medicine
·
2021 - Present
Medicine, Hematology,
Medicine
Recent Publications
The influence of nuclear antigen form on complement activation by systemic lupus erythematosus antinuclear antibody immune complexes determined by a novel immunocapture assay.
Journal Article J Immunol · April 15, 2026 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease in which immune complexes (ICs) consisting of antinuclear autoantibodies (ANAs) and nuclear antigens induce complement activation and contribute to disease pathogenesis. The impact of anti ... Full text Link to item CiteHeparin-induced thrombocytopenia immune complexes activate the inflammasome pathway in a complement-dependent manner.
Journal Article J Thromb Haemost · March 4, 2026 BACKGROUND: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction to heparin caused by pathological immunoglobulin G (IgG) antibodies targeting platelet factor (PF) 4/heparin antigenic complexes. Immune complexes (ICs) consisting of IgG antibo ... Full text Link to item CiteTargeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.
Journal Article Am J Hematol · December 2025 A deeper understanding of sickle cell disease (SCD) pathophysiology is critical for identifying novel therapeutic targets. A hallmark of SCD is abnormal phosphatidylserine (PS) exposure on sickle red blood cells (RBCs), which contributes to anemia, thrombo ... Full text Open Access Link to item CiteRecent Grants
Complement and thrombosis in HIT
ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2025 - 2028Complement activating properties of anti-Sm/RNP antibodies in SLE
ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2026Comparative studies of complement responses to ICs
ResearchResearch Associate · Awarded by National Institutes of Health · 2023 - 2025View All Grants
Education
Jawaharlal Nehru University (India) ·
2007
Ph.D.