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Burton Lasater Scott

Professor of Neurology
Neurology, Movement Disorders
Duke Box 3333, Durham, NC 27710
932 Morreene Rd, Durham, NC 27705

Overview


I am a Movement Disorders Neurologist and see patients at the Morreene Rd Clinic and at the Durham VA Medical Center.
Among the types of movement disorders patients that I see in clinic are individuals who have Parkinson's disease, Essential Tremor, tics, chorea, dystonia, Huntington's disease, tardive movement disorders and Wilson's disease. I use botulinum toxin injections to treat selected patients afflicted with dystonia, tremors, and tics. I manage patients who have undergone deep brain stimulation (DBS) for the treatment of Parkinson's disease, Essential Tremor,and dystonia. In addition to managing patients who have movement disorders, I participate in a variety of clinical trials focussed on improving the management and treatment of Parkinson's disease, Huntington's disease, and dystonia.

Key words: movement disorders, Parkinson's disease, tremors, tics, chorea, dystonia, botulinum toxin injections.

Current Appointments & Affiliations


Professor of Neurology · 2021 - Present Neurology, Movement Disorders, Neurology

Recent Publications


An Open-Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease.

Journal Article Mov Disord · March 5, 2026 BACKGROUND: The classical complement pathway is implicated in the progression of neurodegenerative disease through its ability to drive aberrant removal of synapses, neuroinflammation, and neuronal damage. ANX005 is a humanized monoclonal antibody targetin ... Full text Link to item Cite

Automated Imaging Differentiation for Parkinsonism.

Journal Article JAMA Neurol · May 1, 2025 IMPORTANCE: Magnetic resonance imaging (MRI) paired with appropriate disease-specific machine learning holds promise for the clinical differentiation of Parkinson disease (PD), multiple system atrophy (MSA) parkinsonian variant, and progressive supranuclea ... Full text Link to item Cite

Motor network reorganization associated with rTMS-induced writing improvement in writer's cramp dystonia.

Journal Article Brain Stimul · 2025 BACKGROUND: Writer's cramp (WC) dystonia is an involuntary movement disorder with distributed abnormalities in the brain's motor network. Prior studies established the potential for repetitive transcranial magnetic stimulation (rTMS) to either premotor cor ... Full text Link to item Cite
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Recent Grants


HSG HD PACT Fellowship

Inst. Training Prgm or CMEMentor · Awarded by Huntington Study Group Ltd · 2026 - 2027

Enroll-HD: A Prospective Registry Study in a Global Huntington's Disease Cohort (A CHDI Foundation Project)

Clinical TrialPrincipal Investigator · Awarded by CHDI Foundation · 2012 - 2027

Huntington's Disease Society of America- Center of Excellence (Level 2)

Public ServicePrincipal Investigator · Awarded by Huntington's Disease Society of America · 2023 - 2026

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Education


University of Miami · 1990 M.D.
Duke University · 1984 Ph.D.