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Maria Angelica Selim

Professor of Pathology
Pathology
Duke Box 3712, Durham, NC 27710
3106 Hosp South, Durham, NC

Overview


Malignant melanoma.
Cutaneous lymphomas.
Vulvar inflammatory and pigmented lesions.

Current Appointments & Affiliations


Professor of Pathology · 2013 - Present Pathology, Clinical Science Departments

Recent Publications


A longitudinal, multi-omic atlas reveals the emergence of a spatially organized immunosuppressive ecosystem in resistant melanoma.

Journal Article Cell Rep Med · April 21, 2026 Despite advances in immune checkpoint blockade, resistance in metastatic melanoma remains a major challenge. To decode resistance mechanisms, we generate a comprehensive longitudinal, multi-omic, and spatial atlas of 45 tumor samples across 10 patients. An ... Full text Link to item Cite

Squamous Precursor Lesions of the Vulva: A Practical Approach.

Journal Article Dermatol Clin · April 2026 Vulvar squamous cell carcinoma and its precursors are heterogeneous and classified into 3 biologically distinct subgroups: human papillomavirus (HPV)-associated, HPV-independent TP53-mutated, and HPV-independent TP53-wild type. Although nomenclature is est ... Full text Link to item Cite

Use of p53 immunohistochemistry can improve diagnostic agreement for differentiated vulvar intraepithelial neoplasia (dVIN): an international reproducibility study.

Journal Article Histopathology · January 2026 AIMS: Differentiated or HPV-independent vulvar intraepithelial neoplasia (dVIN) can progress rapidly to invasive cancer and accurate pathological diagnosis is essential to facilitate appropriate interventions. Histological similarities of dVIN with non-neo ... Full text Link to item Cite
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Recent Grants


Detecting missed metastases from nominally early-stage melanomas with pump-probe microscopy

ResearchCo Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2023 - 2026

Improving Accuracy of Next-Generation Microscopy for Early Stage Metastatic Melanoma Detection

ResearchCollaborator · Awarded by National Cancer Institute · 2024 - 2026

The impact of targeting CD40-CD154 pathway in nonhuman primate vascularized composite allograft model

ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2025

View All Grants

Education


University of Buenos Aires, Faculty of Medicine (Argentina) · 1990 M.D.