Senthil Selvaraj | Scholars@Duke

Senthil Selvaraj
Assistant Professor of Medicine

Senthil Selvaraj, MD, MS, MA, is an Assistant Professor of Medicine in the Duke Molecular Physiology Institute and the Division of Cardiology at Duke University Medical Center. Dr. Selvaraj’s translational research explores the therapeutic relevance of cardiovascular metabolism to patients with heart failure. Through early phase work, his research employs deep phenotyping to decipher metabolic mechanisms that may be leveraged for cardiovascular benefit. These studies characterize dynamic changes in exercise physiology, biomarker profiles integrating multi-omic platforms, echocardiography, arterial stiffness, metabolic molecular imaging techniques, and several other modalities. More recently, this line of inquiry has explored the potential benefits of endogenous and exogenous ketogenic therapies among patients with heart failure. Dr. Selvaraj’s work is currently or recently funded by the National Institutes of Health, American Heart Association, Doris Duke Charitable Foundation, Mandel Foundation, Heart Center Leadership Council, Institute for Translational Medicine and Therapeutics, and American Society for Nuclear Cardiology.

Current Appointments & Affiliations

Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2022
Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2022

Contact Information

300 N. Duke Street, Carmichael Building, Office 50-101, Durham, NC 27701
senthil.selvaraj@duke.edu (919) 660-0730
DMPI Faculty Website
ORCID

Background
Education, Training, & Certifications
- advanced HF-transplant fellow, Cardiology, University of Pennsylvania 2021 - 2022
- cardiovascular medicine fellow, Cardiology, University of Pennsylvania 2017 - 2021
- Preventive Cardiology Fellow, Cardiology, Brigham and Women's Hospital 2016 - 2017
- Chief Resident, Brigham and Women's Hospital 2016 - 2017
- Resident, Internal Medicine, Brigham and Women's Hospital 2013 - 2016
- M.D., Northwestern University, Feinberg School of Medicine 2013
Medical Licensure
- 311914. North Carolina. 2022
Expertise
Subject Headings
- Heart Failure
- Metabolism
Research
Selected Grants
- Dissecting the Ketone Metabolic Axis in Heart Failure with Reduced Ejection Fraction awarded by National Institutes of Health 2022 - 2027
External Relationships
- Doris Duke Charitable Foundation
- Hospital of the University of Pennsylvania
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Osborne, Michael T., Iqra Qamar, and Senthil Selvaraj. “A level of confidence: beta-hydroxybutyrate and myocardial glucose uptake suppression on 18F-FDG PET imaging.” J Nucl Cardiol, January 24, 2023. https://doi.org/10.1007/s12350-023-03199-2.
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  - Selvaraj, Senthil, Muthiah Vaduganathan, Brian L. Claggett, Zi Michael Miao, James C. Fang, Orly Vardeny, Akshay S. Desai, et al. “Blood Pressure and Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: DELIVER.” Jacc Heart Fail 11, no. 1 (January 2023): 76–89. https://doi.org/10.1016/j.jchf.2022.09.002.
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  - Selvaraj, Senthil, Stephen J. Greene, Iyanuoluwa Ayodele, Brooke Alhanti, Larry A. Allen, Sabra C. Lewsey, Srinath Adusumalli, et al. “Assessing Heuristic Bias During Care for Patients Hospitalized for Heart Failure: Get With The Guidelines-Heart Failure.” Circ Heart Fail, December 2, 2022, e010069. https://doi.org/10.1161/CIRCHEARTFAILURE.122.010069.
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  - Vidula, M. K., D. P. Kelly, Z. Arany, K. B. Margulies, S. H. Shah, T. P. Cappola, P. E. Bravo, and S. Selvaraj. “Metabolomic Signatures of Myocardial Glucose Uptake on Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography.” Jacc: Basic to Translational Science 7, no. 12 (December 1, 2022): 1264–66. https://doi.org/10.1016/j.jacbts.2022.09.011.
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  - Selvaraj, Senthil, Sara B. Seidelmann, Meshal Soni, Abhijit Bhattaru, Kenneth B. Margulies, Svati H. Shah, Supritha Dugyala, et al. “Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET.” Eur Heart J Cardiovasc Imaging 23, no. 12 (November 17, 2022): 1690–97. https://doi.org/10.1093/ehjci/jeac031.
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  - Rojulpote, Chaitanya, Abhijit Bhattaru, Christopher Jean, Sarah L. Adams, Vandan Patel, Mahesh K. Vidula, Senthil Selvaraj, et al. “Effect of Immunosuppressive Therapy and Biopsy Status in Monitoring Therapy Response in Suspected Cardiac Sarcoidosis.” Jacc Cardiovasc Imaging 15, no. 11 (November 2022): 1944–55. https://doi.org/10.1016/j.jcmg.2022.05.015.
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  - Selvaraj, Senthil, Zhuxuan Fu, Philip Jones, Lydia C. Kwee, Sheryl L. Windsor, Olga Ilkayeva, Christopher B. Newgard, et al. “Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF.” Circulation 146, no. 11 (September 13, 2022): 808–18. https://doi.org/10.1161/CIRCULATIONAHA.122.060402.
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  - Selvaraj, Senthil, Brian Claggett, Michelle C. Johansen, Jonathan W. Cunningham, Rebecca F. Gottesman, Bing Yu, Eric Boerwinkle, Thomas H. Mosley, Amil M. Shah, and Scott D. Solomon. “Apolipoprotein E Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study.” J Card Fail 28, no. 7 (July 2022): 1128–36. https://doi.org/10.1016/j.cardfail.2021.12.011.
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  - Vidula, Mahesh K., Senthil Selvaraj, and Marie A. Guerraty. “Cardiopulmonary transit time: Reinforcing the case for positron emission tomography after heart transplantation.” J Nucl Cardiol 29, no. 3 (June 2022): 1245–47. https://doi.org/10.1007/s12350-020-02514-5.
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  - Selvaraj, Senthil, Kenneth B. Margulies, Supritha Dugyala, Erin Schubert, Ann Tierney, Zoltan Arany, Daniel A. Pryma, et al. “Comparison of Exogenous Ketone Administration Versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial.” J Nucl Med 63, no. 5 (May 2022): 770–76. https://doi.org/10.2967/jnumed.121.262734.
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  - Inciardi, Riccardo M., Brian Claggett, Masatoshi Minamisawa, Sung-Hee Shin, Senthil Selvaraj, Alexandra Gonçalves, Wendy Wang, et al. “Association of Left Atrial Structure and Function With Heart Failure in Older Adults.” J Am Coll Cardiol 79, no. 16 (April 26, 2022): 1549–61. https://doi.org/10.1016/j.jacc.2022.01.053.
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  - Selvaraj, Senthil, Deepak L. Bhatt, Ph Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Rebecca A. Juliano, et al. “Impact of Icosapent Ethyl on Cardiovascular Risk Reduction in Patients With Heart Failure in REDUCE-IT.” J Am Heart Assoc 11, no. 7 (April 5, 2022): e024999. https://doi.org/10.1161/JAHA.121.024999.
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  - Selvaraj, Senthil, Ray Hu, Mahesh K. Vidula, Supritha Dugyala, Ann Tierney, Bonnie Ky, Kenneth B. Margulies, Svati H. Shah, Daniel P. Kelly, and Paco E. Bravo. “Acute Echocardiographic Effects of Exogenous Ketone Administration in Healthy Participants.” J Am Soc Echocardiogr 35, no. 3 (March 2022): 305–11. https://doi.org/10.1016/j.echo.2021.10.017.
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  - Selvaraj, Senthil, Brian L. Claggett, Milton Packer, Faiez Zannad, Inder S. Anand, Burkert Pieske, Ziqiang Zhao, et al. “Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure With Preserved Ejection Fraction.” J Am Heart Assoc 10, no. 17 (September 7, 2021): e022069. https://doi.org/10.1161/JAHA.121.022069.
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  - Selvaraj, Senthil, Brian Claggett, Masatoshi Minamisawa, B Gwen Windham, Lin Y. Chen, Riccardo M. Inciardi, Joel N. Buxbaum, Thomas H. Mosley, Amil M. Shah, and Scott D. Solomon. “Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans.” J Am Coll Cardiol 78, no. 1 (July 6, 2021): 89–91. https://doi.org/10.1016/j.jacc.2021.04.042.
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  - Myhre, Peder L., Senthil Selvaraj, and Scott D. Solomon. “Management of hypertension in heart failure with preserved ejection fraction: is there a blood pressure goal?” Curr Opin Cardiol 36, no. 4 (July 1, 2021): 413–19. https://doi.org/10.1097/HCO.0000000000000852.
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  - Vidula, Mahesh K., Philip Wiener, Senthil Selvaraj, Muhammad Shoaib Khan, Usman Abdul Salam, Chaitanya Rojulpote, Scott D. Metzler, et al. “Diagnostic accuracy of SPECT and PET myocardial perfusion imaging in patients with left bundle branch block or ventricular-paced rhythm.” J Nucl Cardiol 28, no. 3 (June 2021): 981–88. https://doi.org/10.1007/s12350-020-02398-5.
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  - Selvaraj, Senthil, Muhammad Shoaib Khan, Mahesh K. Vidula, Philip C. Wiener, Alejandro E. de Feria, Chaitanya Rojulpote, Sheela Krishnan, et al. “Incremental prognostic value of visually estimated coronary artery calcium in patients undergoing positron emission tomography imaging.” Open Heart 8, no. 1 (May 2021). https://doi.org/10.1136/openhrt-2021-001648.
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  - Selvaraj, Senthil, and Kenneth B. Margulies. “Exogenous ketones in the healthy heart: the plot thickens.” Cardiovasc Res 117, no. 4 (March 21, 2021): 995–96. https://doi.org/10.1093/cvr/cvaa283.
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  - Rodriguez, Jose A., Senthil Selvaraj, and Paco E. Bravo. “Potential Cardiovascular Applications of Total-body PET Imaging.” Pet Clin 16, no. 1 (January 2021): 129–36. https://doi.org/10.1016/j.cpet.2020.09.004.
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  - Selvaraj, Senthil, Jessica Kim, Bilal A. Ansari, Lei Zhao, Mary Ellen Cvijic, Matthew Fronheiser, Jagan Mohan-Rao Vanjarapu, et al. “Body Composition, Natriuretic Peptides, and Adverse Outcomes in Heart Failure With Preserved and Reduced Ejection Fraction.” Jacc Cardiovasc Imaging 14, no. 1 (January 2021): 203–15. https://doi.org/10.1016/j.jcmg.2020.07.022.
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  - Selvaraj, Senthil, Brian L. Claggett, Marc A. Pfeffer, Akshay S. Desai, Finnian R. Mc Causland, Martina M. McGrath, Inder S. Anand, et al. “Serum uric acid, influence of sacubitril-valsartan, and cardiovascular outcomes in heart failure with preserved ejection fraction: PARAGON-HF.” Eur J Heart Fail 22, no. 11 (November 2020): 2093–2101. https://doi.org/10.1002/ejhf.1984.
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  - Selvaraj, Senthil, Stephen J. Greene, Sameed Ahmed M. Khatana, Ashwin S. Nathan, Scott D. Solomon, and Deepak L. Bhatt. “The Landscape of Cardiovascular Clinical Trials in the United States Initiated Before and During COVID-19.” J Am Heart Assoc 9, no. 18 (September 15, 2020): e018274. https://doi.org/10.1161/JAHA.120.018274.
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  - Selvaraj, Senthil, Peder L. Myhre, Muthiah Vaduganathan, Brian L. Claggett, Kunihiro Matsushita, Dalane W. Kitzman, Barry A. Borlaug, Amil M. Shah, and Scott D. Solomon. “Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community.” Jacc Heart Fail 8, no. 8 (August 2020): 640–53. https://doi.org/10.1016/j.jchf.2020.03.013.
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  - Selvaraj, Senthil, Daniel P. Kelly, and Kenneth B. Margulies. “Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure.” Circulation 141, no. 22 (June 2, 2020): 1800–1812. https://doi.org/10.1161/CIRCULATIONAHA.119.045033.
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  - Selvaraj, Senthil, Brian L. Claggett, Michael Böhm, Stefan D. Anker, Muthiah Vaduganathan, Faiez Zannad, Burkert Pieske, et al. “Systolic Blood Pressure in Heart Failure With Preserved Ejection Fraction Treated With Sacubitril/Valsartan.” J Am Coll Cardiol 75, no. 14 (April 14, 2020): 1644–56. https://doi.org/10.1016/j.jacc.2020.02.009.
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  - Selvaraj, Senthil, Brian Claggett, Andrea Pozzi, John J. V. McMurray, Pardeep S. Jhund, Milton Packer, Akshay S. Desai, et al. “Prognostic Implications of Congestion on Physical Examination Among Contemporary Patients With Heart Failure and Reduced Ejection Fraction: PARADIGM-HF.” Circulation 140, no. 17 (October 22, 2019): 1369–79. https://doi.org/10.1161/CIRCULATIONAHA.119.039920.
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  - Imran, Tasnim F., Ariela Orkaby, Jiaying Chen, Senthil Selvaraj, Jane A. Driver, J Michael Gaziano, and Luc Djoussé. “Walking pace is inversely associated with risk of death and cardiovascular disease: The Physicians' Health Study.” Atherosclerosis 289 (October 2019): 51–56. https://doi.org/10.1016/j.atherosclerosis.2019.08.001.
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  - Selvaraj, Senthil, Brian Claggett, Sanjiv J. Shah, Inder S. Anand, Jean L. Rouleau, Akshay S. Desai, Eldrin F. Lewis, et al. “Utility of the Cardiovascular Physical Examination and Impact of Spironolactone in Heart Failure With Preserved Ejection Fraction.” Circ Heart Fail 12, no. 7 (July 2019): e006125. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006125.
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  - Kumar, Anupam, Bilal A. Ansari, Jessica Kim, Arpita Suri, Sowmya Gaddam, Sowjanya Yenigalla, Jagan M. Vanjarapu, et al. “Axial Muscle Size as a Strong Predictor of Death in Subjects With and Without Heart Failure.” J Am Heart Assoc 8, no. 4 (February 19, 2019): e010554. https://doi.org/10.1161/JAHA.118.010554.
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  - Khan, Sadiya S., Kwang-Youn A. Kim, Jie Peng, Frank G. Aguilar, Senthil Selvaraj, Eva E. Martinez, Abigail S. Baldridge, et al. “Clinical correlates and heritability of cardiac mechanics: The HyperGEN study.” Int J Cardiol 274 (January 1, 2019): 208–13. https://doi.org/10.1016/j.ijcard.2018.07.057.
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  - Selvaraj, Senthil, Sara Seidelmann, Odilson M. Silvestre, Brian Claggett, Chiadi E. Ndumele, Susan Cheng, Bing Yu, et al. “HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study.” Hypertension 73, no. 1 (January 2019): 68–74. https://doi.org/10.1161/HYPERTENSIONAHA.118.11730.
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  - Selvaraj, Senthil, Brian Claggett, Sanjiv J. Shah, Inder Anand, Jean L. Rouleau, Eileen O’Meara, Akshay S. Desai, et al. “Prognostic Value of Albuminuria and Influence of Spironolactone in Heart Failure With Preserved Ejection Fraction.” Circ Heart Fail 11, no. 11 (November 2018): e005288. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005288.
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  - Burns, Jacob A., Cynthia Sanchez, Lauren Beussink, Vistasp Daruwalla, Benjamin H. Freed, Senthil Selvaraj, and Sanjiv J. Shah. “Lack of Association Between Anemia and Intrinsic Left Ventricular Diastolic Function or Cardiac Mechanics in Heart Failure With Preserved Ejection Fraction.” Am J Cardiol 122, no. 8 (October 15, 2018): 1359–65. https://doi.org/10.1016/j.amjcard.2018.06.045.
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  - Selvaraj, Senthil, Deepak L. Bhatt, Brian Claggett, Luc Djoussé, Sanjiv J. Shah, Jiaying Chen, Tasnim F. Imran, et al. “Lack of Association Between Heart Failure and Incident Cancer.” J Am Coll Cardiol 71, no. 14 (April 10, 2018): 1501–10. https://doi.org/10.1016/j.jacc.2018.01.069.
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  - Selvaraj, Senthil, Gregg C. Fonarow, Shubin Sheng, Roland A. Matsouaka, Adam D. DeVore, Paul A. Heidenreich, Adrian F. Hernandez, Clyde W. Yancy, and Deepak L. Bhatt. “Association of Electronic Health Record Use With Quality of Care and Outcomes in Heart Failure: An Analysis of Get With The Guidelines-Heart Failure.” J Am Heart Assoc 7, no. 7 (March 30, 2018). https://doi.org/10.1161/JAHA.117.008158.
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  - Selvaraj, Senthil, Brian Claggett, Sanjiv J. Shah, Inder Anand, Jean L. Rouleau, Akshay S. Desai, Eldrin F. Lewis, et al. “Systolic blood pressure and cardiovascular outcomes in heart failure with preserved ejection fraction: an analysis of the TOPCAT trial.” Eur J Heart Fail 20, no. 3 (March 2018): 483–90. https://doi.org/10.1002/ejhf.1060.
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  - Selvaraj, Senthil, Luc Djoussé, Frank G. Aguilar, Eva E. Martinez, Vincenzo B. Polsinelli, Marguerite R. Irvin, Donna K. Arnett, and Sanjiv J. Shah. “Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function: From the HyperGEN Study.” J Am Coll Cardiol 70, no. 6 (August 8, 2017): 715–24. https://doi.org/10.1016/j.jacc.2017.06.036.
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  - Katz, Daniel H., Rahul C. Deo, Frank G. Aguilar, Senthil Selvaraj, Eva E. Martinez, Lauren Beussink-Nelson, Kwang-Youn A. Kim, et al. “Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection Fraction.” J Cardiovasc Transl Res 10, no. 3 (June 2017): 275–84. https://doi.org/10.1007/s12265-017-9739-z.
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  - Selvaraj, Senthil, Sanjiv J. Shah, Mark J. Ommerborn, Cheryl R. Clark, Michael E. Hall, Robert J. Mentz, Saadia Qazi, et al. “Pulmonary Hypertension Is Associated With a Higher Risk of Heart Failure Hospitalization and Mortality in Patients With Chronic Kidney Disease: The Jackson Heart Study.” Circ Heart Fail 10, no. 6 (June 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003940.
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  - Selvaraj, Senthil, Deepak L. Bhatt, Gregg W. Stone, C Michael Gibson, Ph Gabriel Steg, Christian W. Hamm, Matthew J. Price, et al. “"Off-Hours" Versus "On-Hours" Presentation in ST-Segment Elevation Myocardial Infarction: CHAMPION PHOENIX Findings.” J Am Coll Cardiol 68, no. 21 (November 29, 2016): 2385–87. https://doi.org/10.1016/j.jacc.2016.08.023.
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  - Selvaraj, Senthil, Ph Gabriel Steg, Yedid Elbez, Emmanuel Sorbets, Laurent J. Feldman, Kim A. Eagle, E Magnus Ohman, Jacques Blacher, and Deepak L. Bhatt. “Reply: Mean Arterial Pressure Estimation by a Non-Traditional Formula and Fractional Pulse Pressure.” J Am Coll Cardiol 68, no. 6 (August 9, 2016): 669. https://doi.org/10.1016/j.jacc.2016.05.051.
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  - Selvaraj, Senthil, P Gabriel Steg, Yedid Elbez, Emmanuel Sorbets, Laurent J. Feldman, Kim A. Eagle, E Magnus Ohman, Jacques Blacher, and Deepak L. Bhatt. “Reply: Pulse Pressure and Cardiovascular Death.” J Am Coll Cardiol 68, no. 1 (July 5, 2016): 132–33. https://doi.org/10.1016/j.jacc.2016.04.020.
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  - Selvaraj, Senthil, Eva E. Martinez, Frank G. Aguilar, Kwang-Youn A. Kim, Jie Peng, Jin Sha, Marguerite R. Irvin, et al. “Association of Central Adiposity With Adverse Cardiac Mechanics: Findings From the Hypertension Genetic Epidemiology Network Study.” Circ Cardiovasc Imaging 9, no. 6 (June 2016). https://doi.org/10.1161/CIRCIMAGING.115.004396.
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  - Aguilar, Frank G., Senthil Selvaraj, Eva E. Martinez, Daniel H. Katz, Lauren Beussink, Kwang-Youn A. Kim, Jie Ping, et al. “Archeological Echocardiography: Digitization and Speckle Tracking Analysis of Archival Echocardiograms in the HyperGEN Study.” Echocardiography 33, no. 3 (March 2016): 386–97. https://doi.org/10.1111/echo.13095.
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  - Selvaraj, Senthil, Ph Gabriel Steg, Yedid Elbez, Emmanuel Sorbets, Laurent J. Feldman, Kim A. Eagle, E Magnus Ohman, Jacques Blacher, Deepak L. Bhatt, and Deepak L. REACH Registry Investigators. “Pulse Pressure and Risk for Cardiovascular Events in Patients With Atherothrombosis: From the REACH Registry.” J Am Coll Cardiol 67, no. 4 (February 2, 2016): 392–403. https://doi.org/10.1016/j.jacc.2015.10.084.
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  - Bane, Octavia, Sanjiv J. Shah, Michael J. Cuttica, Jeremy D. Collins, Senthil Selvaraj, Neil R. Chatterjee, Christoph Guetter, James C. Carr, and Timothy J. Carroll. “A non-invasive assessment of cardiopulmonary hemodynamics with MRI in pulmonary hypertension.” Magn Reson Imaging 33, no. 10 (December 2015): 1224–35. https://doi.org/10.1016/j.mri.2015.08.005.
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  - Khan, Sadiya S., Michael J. Cuttica, Lauren Beussink-Nelson, Anastasia Kozyleva, Cynthia Sanchez, Hamorabi Mkrdichian, Senthil Selvaraj, Jane E. Dematte, Daniel C. Lee, and Sanjiv J. Shah. “Effects of ranolazine on exercise capacity, right ventricular indices, and hemodynamic characteristics in pulmonary arterial hypertension: a pilot study.” Pulm Circ 5, no. 3 (September 2015): 547–56. https://doi.org/10.1086/682427.
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  - Shah, Sanjiv J., Daniel H. Katz, Senthil Selvaraj, Michael A. Burke, Clyde W. Yancy, Mihai Gheorghiade, Robert O. Bonow, Chiang-Ching Huang, and Rahul C. Deo. “Phenomapping for novel classification of heart failure with preserved ejection fraction.” Circulation 131, no. 3 (January 20, 2015): 269–79. https://doi.org/10.1161/CIRCULATIONAHA.114.010637.
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  - Selvaraj, Senthil, Frank G. Aguilar, Eva E. Martinez, Lauren Beussink, Kwang-Youn A. Kim, Jie Peng, Daniel C. Lee, et al. “Diastolic wall strain: a simple marker of abnormal cardiac mechanics.” Cardiovasc Ultrasound 12 (October 3, 2014): 40. https://doi.org/10.1186/1476-7120-12-40.
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  - Selvaraj, Senthil, Frank G. Aguilar, Eva E. Martinez, Lauren Beussink, Kwang-Youn A. Kim, Jie Peng, Laura Rasmussen-Torvik, et al. “Association of comorbidity burden with abnormal cardiac mechanics: findings from the HyperGEN study.” J Am Heart Assoc 3, no. 3 (April 29, 2014): e000631. https://doi.org/10.1161/JAHA.113.000631.
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  - Burke, Michael A., Daniel H. Katz, Lauren Beussink, Senthil Selvaraj, Deepak K. Gupta, Justin Fox, Sudarsana Chakrabarti, et al. “Prognostic importance of pathophysiologic markers in patients with heart failure and preserved ejection fraction.” Circ Heart Fail 7, no. 2 (March 1, 2014): 288–99. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000854.
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  - Sauer, Andrew J., Senthil Selvaraj, Frank G. Aguilar, Eva E. Martinez, Jane E. Wilcox, Rod Passman, Jeffrey J. Goldberger, Benjamin H. Freed, and Sanjiv J. Shah. “Relationship between repolarization heterogeneity and abnormal myocardial mechanics.” Int J Cardiol 172, no. 1 (March 1, 2014): 289–91. https://doi.org/10.1016/j.ijcard.2013.12.232.
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  - Katz, Daniel H., Senthil Selvaraj, Frank G. Aguilar, Eva E. Martinez, Lauren Beussink, Kwang-Youn A. Kim, Jie Peng, et al. “Association of low-grade albuminuria with adverse cardiac mechanics: findings from the hypertension genetic epidemiology network (HyperGEN) study.” Circulation 129, no. 1 (January 7, 2014): 42–50. https://doi.org/10.1161/CIRCULATIONAHA.113.003429.
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  - Prasad, Vinay, Jason Rho, Senthil Selvaraj, Mike Cheung, Andrae Vandross, and Nancy Ho. “Can a resident's publication record predict fellowship publications?” Plos One 9, no. 3 (2014): e90140. https://doi.org/10.1371/journal.pone.0090140.
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  - Selvaraj, Senthil, Durga S. Borkar, and Vinay Prasad. “Media coverage of medical journals: do the best articles make the news?” Plos One 9, no. 1 (2014): e85355. https://doi.org/10.1371/journal.pone.0085355.
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  - Selvaraj, Senthil, Leonard Ilkhanoff, Michael A. Burke, Benjamin H. Freed, Roberto M. Lang, Eva E. Martinez, and Sanjiv J. Shah. “Association of the frontal QRS-T angle with adverse cardiac remodeling, impaired left and right ventricular function, and worse outcomes in heart failure with preserved ejection fraction.” J Am Soc Echocardiogr 27, no. 1 (January 2014): 74-82.e2. https://doi.org/10.1016/j.echo.2013.08.023.
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  - Kia, L., S. J. Shah, E. Wang, D. Sharma, S. Selvaraj, C. Medina, J. Cahan, H. Mahon, and J. Levitsky. “Role of pretransplant echocardiographic evaluation in predicting outcomes following liver transplantation.” Am J Transplant 13, no. 9 (September 2013): 2395–2401. https://doi.org/10.1111/ajt.12385.
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  - Prasad, Vinay, Andrae Vandross, Caitlin Toomey, Michael Cheung, Jason Rho, Steven Quinn, Satish Jacob Chacko, et al. “A decade of reversal: an analysis of 146 contradicted medical practices.” Mayo Clin Proc 88, no. 8 (August 2013): 790–98. https://doi.org/10.1016/j.mayocp.2013.05.012.
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  - Selvaraj, Senthil, and Vinay Prasad. “Characteristics of cluster randomized trials: are they living up to the randomized trial?” Jama Intern Med 173, no. 4 (February 25, 2013): 313–15. https://doi.org/10.1001/jamainternmed.2013.1638.
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  - Prasad, Vinay, Jason Rho, Senthil Selvaraj, Caitlin Toomey, Andrae Vandross, and Nancy Ho. “Publication trends among internal medicine residents and graduates.” Am J Med 125, no. 9 (September 2012): 939–44. https://doi.org/10.1016/j.amjmed.2012.05.014.
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  - Selvaraj, Senthil, Irwin Klein, Sara Danzi, Nausheen Akhter, Robert O. Bonow, and Sanjiv J. Shah. “Association of serum triiodothyronine with B-type natriuretic peptide and severe left ventricular diastolic dysfunction in heart failure with preserved ejection fraction.” Am J Cardiol 110, no. 2 (July 15, 2012): 234–39. https://doi.org/10.1016/j.amjcard.2012.02.068.
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  - Selvaraj, Senthil, Kevin Liu, Alan M. Robinson, Victoria A. Epstein, David B. Conley, Robert C. Kern, and Claus-Peter Richter. “In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states.” Plos One 7, no. 7 (2012): e39600. https://doi.org/10.1371/journal.pone.0039600.
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- Conference Papers
  - Selvaraj, Senthil, Kenneth Margulies, Svati Shah, Supritha Dugyala, Erin Schubert, Daniel Pryma, Daniel Kelly, and Paco Bravo. “Endogenous versus Exogenous Ketosis to Suppress Myocardial Glucose Uptake on FDG-PET: KEETO-CROSS.” In Journal of Nuclear Medicine, Vol. 62, 2021.
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Education, Training, & Certifications

Medical Licensure

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Conference Papers