Overview
The focus of my research is on the care of patients with advanced heart failure. We are involved in single and multicenter clinical trials evaluating new drug therapies for patients with advanced heart failure. Additionally, we are working to understand the exercise limitations and how to improve them in this patient population. We are trying to understand some of the basic pathophysiologic consequences of heart failure such as the origin of the symptoms of dyspnea and fatigue.
We have established an invasive cardiopulmonary exercise lab in which we carry out the majority of our research. We have the ability to monitor hemodynamics and gas exchange during exercise. Additionally, we have been the exercise core lab for various trials involving exercise as an endpoint in the evaluation of new therapies for heart failure.
Key words include: Advanced heart failure, Exercise physiology, and Cardiac transplantation.
We have established an invasive cardiopulmonary exercise lab in which we carry out the majority of our research. We have the ability to monitor hemodynamics and gas exchange during exercise. Additionally, we have been the exercise core lab for various trials involving exercise as an endpoint in the evaluation of new therapies for heart failure.
Key words include: Advanced heart failure, Exercise physiology, and Cardiac transplantation.
Current Appointments & Affiliations
Professor of Medicine
·
2021 - Present
Medicine, Cardiology,
Medicine
Recent Publications
Pressure points: Hemodynamics and waitlist risk before heart transplant.
Journal Article J Heart Lung Transplant · November 21, 2025 Full text Link to item CiteImpact of HeartMate 3 left ventricular assist device infection on outcomes following heart transplant.
Journal Article J Heart Lung Transplant · November 13, 2025 BACKGROUND: Infectious complications are common in patients implanted with HeartMate 3 (HM3) left ventricular assist devices (LVAD). Despite these issues, some patients with LVAD-specific infection are ultimately considered for heart transplant (HT). The i ... Full text Link to item CiteLate follow-up for a randomized trial of surgical treatment of tricuspid valve regurgitation in patients undergoing left ventricular assist device implantation.
Journal Article J Thorac Cardiovasc Surg · July 2025 BACKGROUND: We previously reported that concurrent tricuspid valve surgery (TVS) was not associated with a lower incidence of early right heart failure (RHF) in patients undergoing durable left ventricular assist device (LVAD) implantation. This follow-up ... Full text Link to item CiteRecent Grants
The Atherosclerosis Risk in Communities (ARIC) Study-Field Center
ResearchPrincipal Investigator · Awarded by Johns Hopkins University · 2017 - 2026Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catherization Effectiveness (ESCAPE), RFP NHLBI-HV-98-24
Clinical TrialPrincipal Investigator · Awarded by National Heart, Lung, and Blood Institute · 1999 - 2002View All Grants
Education, Training & Certifications
University of Washington, School of Medicine ·
1991
M.D.