Scholars@Duke
Stefanie Gail Schuman

Stefanie Gail Schuman

Associate Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery
stefanie.schuman@duke.edu
Box 3802 Med Ctr, Durham, NC 27710
Aeri Bldg 2351 Erwin Rd, Durham, NC 27710
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Selected Publications

Impact of Bariatric Surgery on Treatment Burden and Progression of Diabetic Retinopathy.

Journal Article Journal of vitreoretinal diseases · May 2024 Purpose: To assess the severity, progression, and treatment burden of diabetic retinopathy (DR) in patients after bariatric surgery compared with controls. Methods: A retrospective cohort study was performed of patients with type 2 diabetes a ... Full text Cite

A Deep-Learning Algorithm to Predict Short-Term Progression to Geographic Atrophy on Spectral-Domain Optical Coherence Tomography.

Journal Article JAMA Ophthalmol · November 1, 2023 IMPORTANCE: The identification of patients at risk of progressing from intermediate age-related macular degeneration (iAMD) to geographic atrophy (GA) is essential for clinical trials aimed at preventing disease progression. DeepGAze is a fully automated a ... Full text Link to item Cite

Machine learning OCT predictors of progression from intermediate age-related macular degeneration to geographic atrophy and vision loss.

Journal Article Ophthalmol Sci · June 2022 OBJECTIVE: To describe optical coherence tomography (SD-OCT) features, age, gender, and systemic variables that may be used in machine/deep learning studies to identify high-risk patient subpopulations with high risk of progression to geographic atrophy (G ... Full text Link to item Cite

Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT.

Journal Article Ophthalmol Retina · May 2021 PURPOSE: In macula-wide analyses, spectral-domain (SD) optical coherence tomography (OCT) features including drusen volume, hyperreflective foci, and OCT-reflective drusen substructures independently predict geographic atrophy (GA) onset secondary to age-r ... Full text Link to item Cite

Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months.

Journal Article Ophthalmol Retina · August 2019 PURPOSE: To report the 1-year progression of visual impairment on psychophysical tests of visual function in patients with early and intermediate age-related macular degeneration (AMD). DESIGN: Prospective, observational study. PARTICIPANTS: Patients with ... Full text Link to item Cite

Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Journal Article Ophthalmology · February 2019 PURPOSE: To investigate the natural history and genetic associations of drusenoid pigment epithelial detachment (DPED) associated with age-related macular degeneration (AMD). DESIGN: Retrospective analysis of a prospective cohort study. PARTICIPANTS: Of th ... Full text Link to item Cite

Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Journal Article Ophthalmology · December 2018 PURPOSE: To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD), including clinical and genetic factors affecting enlargement. DESIGN: Prospective cohort study withi ... Full text Link to item Cite

Visual Function Metrics in Early and Intermediate Dry Age-related Macular Degeneration for Use as Clinical Trial Endpoints.

Journal Article Am J Ophthalmol · May 2018 PURPOSE: To evaluate and quantify visual function metrics to be used as endpoints of age-related macular degeneration (AMD) stages and visual acuity (VA) loss in patients with early and intermediate AMD. DESIGN: Cross-sectional analysis of baseline data fr ... Full text Link to item Cite

Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration.

Conference Ophthalmology · December 2017 PURPOSE: Appearance of geographic atrophy (GA) on color photography (CP) is preceded by specific features on spectral-domain optical coherence tomography (SD OCT). We aimed to build SD OCT-based risk assessment models for 5-year new onset of GA and central ... Full text Link to item Cite

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration.

Journal Article Invest Ophthalmol Vis Sci · March 1, 2017 PURPOSE: We assess the effect of intravitreal anti-VEGF injections on tonographic outflow facility. METHODS: Patients with age-related macular degeneration who had received unilateral intravitreal anti-VEGF injections were recruited into two groups, those ... Full text Link to item Cite

Screening for Diabetic Retinopathy Using a Portable, Noncontact, Nonmydriatic Handheld Retinal Camera.

Journal Article J Diabetes Sci Technol · January 2017 BACKGROUND: Diabetic retinopathy (DR) is a leading cause of low vision and blindness. We evaluated the feasibility of using a handheld, noncontact digital retinal camera, Pictor, to obtain retinal images in dilated and undilated eyes for DR screening. We a ... Full text Link to item Cite

Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration.

Journal Article Ophthalmology · December 2016 PURPOSE: Structural and compositional heterogeneity within drusen comprising lipids, carbohydrates, and proteins have been previously described. We sought to detect and define phenotypic patterns of drusen heterogeneity in the form of optical coherence tom ... Full text Link to item Cite

Wide field of view swept-source optical coherence tomography for peripheral retinal disease.

Journal Article Br J Ophthalmol · October 2016 BACKGROUND/AIMS: To assess peripheral retinal lesions and the posterior pole in single widefield optical coherence tomography (OCT) volumes. METHODS: A wide field of view (FOV) swept-source OCT (WFOV SSOCT) system was developed using a commercial swept-sou ... Full text Link to item Cite

DYNAMIC CHANGES OF THE ANTERIOR CHAMBER ANGLE PRODUCED BY INTRAVITREAL ANTI-VASCULAR GROWTH FACTOR INJECTIONS.

Journal Article Retina · October 2016 PURPOSE: To use anterior segment optical coherence tomography (AS-OCT) to evaluate the anterior chamber after intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections. METHODS: Preinjection and immediate postinjection AS-OCT images were ... Full text Link to item Cite

VISUAL FUNCTION MEASURES IN EARLY AND INTERMEDIATE AGE-RELATED MACULAR DEGENERATION.

Journal Article Retina · May 2016 PURPOSE: The objectives of this study were to evaluate 1) the feasibility of performing computerized tests of low luminance visual acuity (LLVA), cone-specific contrast (Cone Contrast Test [CCT]), contrast sensitivity, and microperimetry and 2) the test-re ... Full text Link to item Cite

Prevalence of vitreomacular adhesion: an optical coherence tomography analysis in the retina clinic setting.

Journal Article Clin Ophthalmol · 2016 PURPOSE: The aims of this study were to determine the prevalence of vitreomacular adhesion (VMA) in a random sample of clinical patients at three US retina clinics and to assess comorbid retinal conditions, ocular diseases, prior treatment history, and oth ... Full text Link to item Cite

Spatial correlation between hyperpigmentary changes on color fundus photography and hyperreflective foci on SDOCT in intermediate AMD.

Journal Article Invest Ophthalmol Vis Sci · July 9, 2012 PURPOSE: Macular hyperpigmentation is associated with progression from intermediate to advanced age-related macular degeneration (AMD). The purpose of this study was to accurately correlate hyperpigmentary changes with spectral domain optical coherence tom ... Full text Link to item Cite

Impact of Bariatric Surgery on Treatment Burden and Progression of Diabetic Retinopathy.

Journal Article Journal of vitreoretinal diseases · May 2024 Purpose: To assess the severity, progression, and treatment burden of diabetic retinopathy (DR) in patients after bariatric surgery compared with controls. Methods: A retrospective cohort study was performed of patients with type 2 diabetes a ... Full text Cite

A Deep-Learning Algorithm to Predict Short-Term Progression to Geographic Atrophy on Spectral-Domain Optical Coherence Tomography.

Journal Article JAMA Ophthalmol · November 1, 2023 IMPORTANCE: The identification of patients at risk of progressing from intermediate age-related macular degeneration (iAMD) to geographic atrophy (GA) is essential for clinical trials aimed at preventing disease progression. DeepGAze is a fully automated a ... Full text Link to item Cite

Machine learning OCT predictors of progression from intermediate age-related macular degeneration to geographic atrophy and vision loss.

Journal Article Ophthalmol Sci · June 2022 OBJECTIVE: To describe optical coherence tomography (SD-OCT) features, age, gender, and systemic variables that may be used in machine/deep learning studies to identify high-risk patient subpopulations with high risk of progression to geographic atrophy (G ... Full text Link to item Cite

Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT.

Journal Article Ophthalmol Retina · May 2021 PURPOSE: In macula-wide analyses, spectral-domain (SD) optical coherence tomography (OCT) features including drusen volume, hyperreflective foci, and OCT-reflective drusen substructures independently predict geographic atrophy (GA) onset secondary to age-r ... Full text Link to item Cite

Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months.

Journal Article Ophthalmol Retina · August 2019 PURPOSE: To report the 1-year progression of visual impairment on psychophysical tests of visual function in patients with early and intermediate age-related macular degeneration (AMD). DESIGN: Prospective, observational study. PARTICIPANTS: Patients with ... Full text Link to item Cite

Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Journal Article Ophthalmology · February 2019 PURPOSE: To investigate the natural history and genetic associations of drusenoid pigment epithelial detachment (DPED) associated with age-related macular degeneration (AMD). DESIGN: Retrospective analysis of a prospective cohort study. PARTICIPANTS: Of th ... Full text Link to item Cite

Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Journal Article Ophthalmology · December 2018 PURPOSE: To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD), including clinical and genetic factors affecting enlargement. DESIGN: Prospective cohort study withi ... Full text Link to item Cite

Visual Function Metrics in Early and Intermediate Dry Age-related Macular Degeneration for Use as Clinical Trial Endpoints.

Journal Article Am J Ophthalmol · May 2018 PURPOSE: To evaluate and quantify visual function metrics to be used as endpoints of age-related macular degeneration (AMD) stages and visual acuity (VA) loss in patients with early and intermediate AMD. DESIGN: Cross-sectional analysis of baseline data fr ... Full text Link to item Cite

Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration.

Conference Ophthalmology · December 2017 PURPOSE: Appearance of geographic atrophy (GA) on color photography (CP) is preceded by specific features on spectral-domain optical coherence tomography (SD OCT). We aimed to build SD OCT-based risk assessment models for 5-year new onset of GA and central ... Full text Link to item Cite

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration.

Journal Article Invest Ophthalmol Vis Sci · March 1, 2017 PURPOSE: We assess the effect of intravitreal anti-VEGF injections on tonographic outflow facility. METHODS: Patients with age-related macular degeneration who had received unilateral intravitreal anti-VEGF injections were recruited into two groups, those ... Full text Link to item Cite

Screening for Diabetic Retinopathy Using a Portable, Noncontact, Nonmydriatic Handheld Retinal Camera.

Journal Article J Diabetes Sci Technol · January 2017 BACKGROUND: Diabetic retinopathy (DR) is a leading cause of low vision and blindness. We evaluated the feasibility of using a handheld, noncontact digital retinal camera, Pictor, to obtain retinal images in dilated and undilated eyes for DR screening. We a ... Full text Link to item Cite

Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration.

Journal Article Ophthalmology · December 2016 PURPOSE: Structural and compositional heterogeneity within drusen comprising lipids, carbohydrates, and proteins have been previously described. We sought to detect and define phenotypic patterns of drusen heterogeneity in the form of optical coherence tom ... Full text Link to item Cite

Wide field of view swept-source optical coherence tomography for peripheral retinal disease.

Journal Article Br J Ophthalmol · October 2016 BACKGROUND/AIMS: To assess peripheral retinal lesions and the posterior pole in single widefield optical coherence tomography (OCT) volumes. METHODS: A wide field of view (FOV) swept-source OCT (WFOV SSOCT) system was developed using a commercial swept-sou ... Full text Link to item Cite

DYNAMIC CHANGES OF THE ANTERIOR CHAMBER ANGLE PRODUCED BY INTRAVITREAL ANTI-VASCULAR GROWTH FACTOR INJECTIONS.

Journal Article Retina · October 2016 PURPOSE: To use anterior segment optical coherence tomography (AS-OCT) to evaluate the anterior chamber after intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections. METHODS: Preinjection and immediate postinjection AS-OCT images were ... Full text Link to item Cite

VISUAL FUNCTION MEASURES IN EARLY AND INTERMEDIATE AGE-RELATED MACULAR DEGENERATION.

Journal Article Retina · May 2016 PURPOSE: The objectives of this study were to evaluate 1) the feasibility of performing computerized tests of low luminance visual acuity (LLVA), cone-specific contrast (Cone Contrast Test [CCT]), contrast sensitivity, and microperimetry and 2) the test-re ... Full text Link to item Cite

Prevalence of vitreomacular adhesion: an optical coherence tomography analysis in the retina clinic setting.

Journal Article Clin Ophthalmol · 2016 PURPOSE: The aims of this study were to determine the prevalence of vitreomacular adhesion (VMA) in a random sample of clinical patients at three US retina clinics and to assess comorbid retinal conditions, ocular diseases, prior treatment history, and oth ... Full text Link to item Cite

Spatial correlation between hyperpigmentary changes on color fundus photography and hyperreflective foci on SDOCT in intermediate AMD.

Journal Article Invest Ophthalmol Vis Sci · July 9, 2012 PURPOSE: Macular hyperpigmentation is associated with progression from intermediate to advanced age-related macular degeneration (AMD). The purpose of this study was to accurately correlate hyperpigmentary changes with spectral domain optical coherence tom ... Full text Link to item Cite

Photoreceptor layer thinning over drusen in eyes with age-related macular degeneration imaged in vivo with spectral-domain optical coherence tomography.

Journal Article Ophthalmology · March 2009 PURPOSE: Detect changes in the neurosensory retina using spectral-domain optical coherence tomography (SD OCT) imaging over drusen in age-related macular degeneration (AMD). Quantitative imaging biomarkers may aid in defining risk of disease progression. D ... Full text Link to item Cite

Management of glaucoma drainage implant tube kink and obstruction with Pars Plana Clip.

Journal Article Ophthalmic Surg Lasers Imaging · 2005 Increased intraocular pressure after glaucoma drainage implant surgery may be caused by obstruction of the tube. A case of obstruction of an Ahmed glaucoma valve tube after pars plana insertion due to kinking of the tube was treated with a Pars Plana Clip ... Link to item Cite

Wavelength independence and interdevice variability of optical coherence tomography.

Journal Article Ophthalmic Surg Lasers Imaging · 2004 BACKGROUND AND OBJECTIVE: Comparison of nerve fiber layer (NFL) thickness and macular retinal thickness measurements in two different commercial optical coherence tomography (OCT) machines with the same and different super luminescent diode lasers (SLDs). ... Link to item Cite

Usage and cost of laser trabeculoplasty in the United States.

Journal Article Ophthalmic Surg Lasers · 2002 To determine annual usage and costs of laser trabeculoplasty (LTP) in the United States, we reviewed data from the Health Care Financing Administration from 1986 to 2000, using the Part B Extract and Summary System (BESS). The annual number of LTP procedur ... Link to item Cite

Comparison of fornix versus limbus based combined phacoemulsification and trabeculectomy with mitomycin C

Conference Investigative Ophthalmology and Visual Science · February 15, 1996 Purpose. To determine if there is a difference in operating time, intraoperative and postoperative complications, and results between limbus vs. fornix based conjunctival flaps in combined phacoemulsification and trabeculectomy with MMC. Methods. A prospec ... Cite