Overview
Geriatric Affective Disorders
Geriatric Cognitive Disorders
Alzheimer's Disease
ECT
Geriatric Cognitive Disorders
Alzheimer's Disease
ECT
Current Appointments & Affiliations
Professor Emeritus of Psychiatry and Behavioral Sciences
·
2013 - Present
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology,
Psychiatry & Behavioral Sciences
Recent Publications
Right anterior supramarginal gyrus-cerebellum hyperconnectivity and rumination partially mediate the link between childhood abuse and anger in late-life depression
Journal Article Journal of Affective Disorders · March 15, 2026 Background Childhood abuse is linked to emotional dysregulation and anger across the lifespan, but its neural correlates in late-life depression (LLD) remain unclear. Methods Ninety-eight adults aged ≥60 years with LLD underwent resting-state functional ma ... Full text CiteIterative learning for joint image denoising and motion artifact correction of 3D brain MRI.
Journal Article Med Image Anal · February 2026 Image noise and motion artifacts greatly affect the quality of brain magnetic resonance imaging (MRI) and negatively influence downstream medical image analysis. Previous studies often focus on 2D methods that process each volumetric MR image slice-by-slic ... Full text Link to item CiteECL-CRISPR array for multiplexed detection of miRNAs.
Journal Article Biosens Bioelectron · December 1, 2025 We describe here an electrochemiluminescent (ECL) array for individually detecting 3 miRNAs utilizing CRISPR/Cas13a. Detection involves binding a target miRNA to Cas 13a protein that includes the RNA complement to the target, This activated Cas13a then cle ... Full text Link to item CiteRecent Grants
Anhedonia, Aging, and the Neural Correlates of Attentional Control in Depression
ResearchMentor · Awarded by National Institutes of Health · 2010 - 2015Emotion Regulation in Late-Life Depression: Effectiveness and Neural Mechanisms
ResearchMentor · Awarded by National Institutes of Health · 2009 - 2015Cognitive Endophenotypes for Genetic Studies of Alzheimer's Disease
ResearchCollaborator · Awarded by National Institutes of Health · 2007 - 2012View All Grants
Education, Training & Certifications
Duke University ·
2000
M.H.S.
University of Texas, Dallas ·
1988
M.D.