Scholars@Duke

• Background
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  Education, Training, & Certifications

  • Ph.D., Wayne State University 2017
• Research
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  Selected Grants

  • Multi-scale characterization of radiation resistance in head and neck squamous cell carcinoma awarded by Department of Defense 2021 - 2024
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Blocker, Stephanie J., Samantha Morrison, Jeffrey I. Everitt, James Cook, Sheng Luo, Tammara L. Watts, and Yvonne M. Mowery. “Whole-Slide Cytometric Feature Mapping for Distinguishing Tumor Genomic Subtypes in Head and Neck Squamous Cell Carcinoma Whole-Slide Images.” Am J Pathol 193, no. 2 (February 2023): 182–90. https://doi.org/10.1016/j.ajpath.2022.11.004.
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    • Enam, Syed Faaiz, Cem Y. Kilic, Jianxi Huang, Brian J. Kang, Reed Chen, Connor S. Tribble, Ekaterina Ilich, et al. “Cytostatic hypothermia and its impact on glioblastoma and survival.” Sci Adv 8, no. 47 (November 25, 2022): eabq4882. https://doi.org/10.1126/sciadv.abq4882.
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    • Blocker, Stephanie J., James Cook, Jeffrey I. Everitt, Wyatt M. Austin, Tammara L. Watts, and Yvonne M. Mowery. “Automated Nuclear Segmentation in Head and Neck Squamous Cell Carcinoma Pathology Reveals Relationships between Cytometric Features and ESTIMATE Stromal and Immune Scores.” Am J Pathol 192, no. 9 (September 2022): 1305–20. https://doi.org/10.1016/j.ajpath.2022.06.003.
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    • Bishawi, Muath, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, et al. “Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.” Iscience 25, no. 4 (April 15, 2022): 104086. https://doi.org/10.1016/j.isci.2022.104086.
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    • Blocker, Stephanie J., James Cook, Yvonne M. Mowery, Jeffrey I. Everitt, Yi Qi, Kathryn J. Hornburg, Gary P. Cofer, et al. “Ex Vivo MR Histology and Cytometric Feature Mapping Connect Three-dimensional in Vivo MR Images to Two-dimensional Histopathologic Images of Murine Sarcomas.” Radiol Imaging Cancer 3, no. 3 (May 2021): e200103. https://doi.org/10.1148/rycan.2021200103.
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    • Huang, Qiang, Aliesha Garrett, Shree Bose, Stephanie Blocker, Anne C. Rios, Hans Clevers, and Xiling Shen. “The frontier of live tissue imaging across space and time.” Cell Stem Cell 28, no. 4 (April 1, 2021): 603–22. https://doi.org/10.1016/j.stem.2021.02.010.
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    • Shoghi, Kooresh I., Cristian T. Badea, Stephanie J. Blocker, Thomas L. Chenevert, Richard Laforest, Michael T. Lewis, Gary D. Luker, et al. “Co-Clinical Imaging Resource Program (CIRP): Bridging the Translational Divide to Advance Precision Medicine.” Tomography 6, no. 3 (September 2020): 273–87. https://doi.org/10.18383/j.tom.2020.00023.
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    • Holbrook, M. D., S. J. Blocker, Y. M. Mowery, A. Badea, Y. Qi, E. S. Xu, D. G. Kirsch, G. A. Johnson, and C. T. Badea. “MRI-Based Deep Learning Segmentation and Radiomics of Sarcoma in Mice.” Tomography 6, no. 1 (March 2020): 23–33. https://doi.org/10.18383/j.tom.2019.00021.
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    • Blocker, S. J., M. D. Holbrook, Y. M. Mowery, D. C. Sullivan, and C. T. Badea. “The impact of respiratory gating on improving volume measurement of murine lung tumors in micro-CT imaging.” Plos One 15, no. 2 (2020): e0225019. https://doi.org/10.1371/journal.pone.0225019.
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    • Blocker, S. J., Y. M. Mowery, M. D. Holbrook, Y. Qi, D. G. Kirsch, G. A. Johnson, and C. T. Badea. “Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial.” Plos One 14, no. 4 (2019): e0207555. https://doi.org/10.1371/journal.pone.0207555.
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    • Blocker, Stephanie J., and Anthony F. Shields. “Imaging of Nanoparticle Distribution to Assess Treatments That Alter Delivery.” Mol Imaging Biol 20, no. 3 (June 2018): 340–51. https://doi.org/10.1007/s11307-017-1142-2.
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    • Lee, Helen, Anthony F. Shields, Barry A. Siegel, Kathy D. Miller, Ian Krop, Cynthia X. Ma, Patricia M. LoRusso, et al. “64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.” Clin Cancer Res 23, no. 15 (August 1, 2017): 4190–4202. https://doi.org/10.1158/1078-0432.CCR-16-3193.
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    • Blocker, Stephanie J., Kirk A. Douglas, Lisa Anne Polin, Helen Lee, Bart S. Hendriks, Enxhi Lalo, Wei Chen, and Anthony F. Shields. “Liposomal 64Cu-PET Imaging of Anti-VEGF Drug Effects on Liposomal Delivery to Colon Cancer Xenografts.” Theranostics 7, no. 17 (2017): 4229–39. https://doi.org/10.7150/thno.21688.
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  • Book Sections

    • McHugh, C. I., S. J. Blocker, N. Viola-Villegas, and A. F. Shields. “Cancer imaging in preclinical models.” In Animal Models in Cancer Drug Discovery, 373–400, 2019. https://doi.org/10.1016/B978-0-12-814704-7.00016-7.
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  • Conference Papers

    • Enam, Syed Faaiz, Jianxi Huang, Cem Kilic, Connor Tribble, Martha Betancur, Stephanie Blocker, Steven Owen, and Ravi Bellamkonda. “CYTOSTATIC HYPOTHERMIA FOR GLIOBLASTOMA.” In Neuro Oncology, 22:103–103, 2020.
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    • Holbrook, M. D., S. J. Blocker, Y. Mowery, A. Badea, Y. Qi, D. G. Kirsch, and C. T. Badea. “MRI-based radiomics of sarcomas in the preclinical arm of a Co-clinical trial.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 11317, 2020. https://doi.org/10.1117/12.2549628.
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    • Blocker, S. J., M. Holbrook, Y. M. Mowery, and C. T. Badea. “To gate or not to gate: An evaluation of respiratory gating techniques to improve volume measurement of murine lung tumors in micro-CT imaging.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 10953, 2019. https://doi.org/10.1117/12.2512534.
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    • Holbrook, M., S. J. Blocker, Y. M. Mowery, and C. T. Badea. “Multi-modal MRI segmentation of sarcoma tumors using convolutional neural networks.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 10948, 2019. https://doi.org/10.1117/12.2512822.
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  • Preprints

    • Blocker, Stephanie, Samantha Morrison, Jeffrey Everitt, James Cook, Sheng Luo, Tammara Watts, and Yvonne Mowery. “Whole-slide cytometric feature mapping for distinguishing tumor genomic subtypes in HNSCC whole slide images.” Research Square, 2022. https://doi.org/10.21203/rs.3.rs-1785010/v1.
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