Jason Eric Stout | Scholars@Duke

Jason Eric Stout
Professor of Medicine

My research focuses on the epidemiology, natural history, and treatment of tuberculosis and nontuberculous mycobacterial infections. I am also interested in the impact of HIV infection on mycobacterial infection and disease, and in examining health disparities as they relate to infectious diseases, particularly in immigrant populations.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Infectious Diseases, Medicine 2017

Contact Information

181 Hanes House, Durham, NC 27710
Duke Box 102359, Durham, NC 27710
stout002@mc.duke.edu (919) 668-0826

Background
Education, Training, & Certifications
- Fellow in Infectious Diseases, Medicine, Duke University 1999 - 2002
- Medical Resident, Medicine, Duke University 1996 - 1999
- M.D., SUNY Upstate Medical University 1996
Duke Appointment History
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2013 - 2017
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2013
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2004 - 2010
- Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2004
Leadership & Clinical Positions at Duke
- Medical Director, Adult Infectious Diseases Clinic, 1/2008-1/2018
  Vice Chief for Clinical Affairs, Division of Infectious Diseases, 1/2008-1/2018
Recognition
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Macrophage Reprogramming During Granuloma Formation in the Zebrafish awarded by National Institutes of Health 2017 - 2022
- Genetic dissection of angiogenesis in the tuberculous granuloma awarded by National Institutes of Health 2017 - 2022
- Prospective Comparison of the Tuberculin Skin Test (TST) vs. Interferon Gamma Release Assays (IGRAs) in Diagnosing Laten 2011 - 2021
- The Genetic Basis of Bone Disease in Mycobacterial Infection awarded by National Institutes of Health 2017 - 2021
- The Genetic Basis of Bone Disease in Mycobacterial Infection awarded by National Institutes of Health 2017 - 2021
- Prospective Comparison of the Tuberculin Skin Test (TST) vs. Interferon Gamma Release Assays (IGRAs) in Diagnosing Laten 2011 - 2020
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- Epidemiology/General Communicable Disease Control 2019
- Tuberculosis Trial Consortium 2015 - 2019
- Prospective Comparison of the Tuberculin Skin Test (TST) vs. Interferon Gamma Release Assays (IGRAs) in Diagnosing Laten 2011 - 2019
- Epidemiology/General Communicable Disease Control 2018
- Tuberculosis Trial Consortium 2015 - 2018
- Epidemiology/General Communicable Disease Control 2017
- The Genetic Basis of Bone Disease in Mycobacterial Infection awarded by National Institutes of Health 2014 - 2017
- Role of Developmental Signaling Pathways in Tuberculosis Pathogenesis awarded by National Institutes of Health 2017
- Tuberculosis Trial Consortium 2009 - 2014
- Mathematical Modeling in Clinical Trials of Tuberculosis Therapeutics awarded by National Institutes of Health 2009 - 2014
- Large Scale Antibody and TCell Epitope Discovery awarded by National Institutes of Health 2004 - 2011
- Role of non-tuberculous mycobacteria in lung disease awarded by National Institutes of Health 2003 - 2008
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Stout, Jason E., Timothy R. Sterling, and C Robert Horsburgh. “One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis..” N Engl J Med 381, no. 11 (September 12, 2019). https://doi.org/10.1056/NEJMc1908492.
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  - Whitley, Melodi Javid, Jason E. Stout, Atul Kapila, M Angelica Selim, Parisa Mansoori, and Anne L. Marano. “Papulonecrotic tuberculid and Poncet disease: A case of multisystem delayed-type hypersensitivity in a patient with Mycobacterium tuberculosis infection..” Jaad Case Rep 5, no. 9 (September 2019): 794–97. https://doi.org/10.1016/j.jdcr.2019.07.002.
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  - Dicks, Kristen V., and Jason E. Stout. “Molecular Diagnostics for Mycobacterium tuberculosis Infection..” Annu Rev Med 70 (January 27, 2019): 77–90. https://doi.org/10.1146/annurev-med-040717-051502.
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  - Stout, Jason E., Yanjue Wu, Christine S. Ho, April C. Pettit, Pei-Jean Feng, Dolly J. Katz, Smita Ghosh, Thara Venkatappa, Ruiyan Luo, and Ruiyan Tuberculosis Epidemiologic Studies Consortium. “Evaluating latent tuberculosis infection diagnostics using latent class analysis..” Thorax 73, no. 11 (November 2018): 1062–70. https://doi.org/10.1136/thoraxjnl-2018-211715.
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  - Dicks, Kristen V., David P. Holland, Myra G. Allen, Ellen R. Fortenberry, Julie Luffman, Elizabeth Zeringue, Jennifer Wheeler, and Jason E. Stout. “Impact of radiology reports on timely tuberculosis diagnosis..” Postgrad Med J 94, no. 1115 (September 2018): 495–98. https://doi.org/10.1136/postgradmedj-2018-135984.
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  - Hemmersbach-Miller, Marion, Jason E. Stout, Michael H. Woodworth, Gary M. Cox, and Jennifer L. Saullo. “Nocardia infections in the transplanted host..” Transpl Infect Dis 20, no. 4 (August 2018). https://doi.org/10.1111/tid.12902.
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  - Rinsky, Jessica L., Darlene Farmer, Jessica Dixon, Jean-Marie Maillard, Thomas Young, Jason Stout, Amina Ahmed, Aaron Fleischauer, Jennifer MacFarquhar, and Zack Moore. “Notes from the Field: Contact Investigation for an Infant with Congenital Tuberculosis Infection - North Carolina, 2016..” Mmwr Morb Mortal Wkly Rep 67, no. 23 (June 15, 2018): 670–71. https://doi.org/10.15585/mmwr.mm6723a5.
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  - Johnson, Douglas F., and Jason E. Stout. “Corticosteroids for tuberculous pericarditis: can we learn from variability?.” Int J Tuberc Lung Dis 22, no. 5 (May 1, 2018). https://doi.org/10.5588/ijtld.18.0134.
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  - Okeke, Nwora Lance, Meredith E. Clement, Mehri S. McKellar, and Jason E. Stout. “Health Care Utilization Behaviors Predict Disengagement From HIV Care: A Latent Class Analysis..” Open Forum Infect Dis 5, no. 5 (May 2018). https://doi.org/10.1093/ofid/ofy088.
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  - Stout, J. E., R. Belknap, Y. -. J. Wu, and C. S. Ho. “Paradox of serial interferon-gamma release assays: variability width more important than specificity size..” Int J Tuberc Lung Dis 22, no. 5 (May 1, 2018): 518–23. https://doi.org/10.5588/ijtld.17.0650.
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  - Ingen, Jakko van, Timothy Aksamit, Claire Andrejak, Erik C. Böttger, Emmanuelle Cambau, Charles L. Daley, David E. Griffith, et al. “Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement..” Eur Respir J 51, no. 3 (March 2018). https://doi.org/10.1183/13993003.00170-2018.
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  - Saelens, Joseph W., Dalia Lau-Bonilla, Anneliese Moller, Ana M. Xet-Mull, Narda Medina, Brenda Guzmán, Maylena Calderón, et al. “Annotated Genome Sequences of 16 Lineage 4 Mycobacterium tuberculosis Strains from Guatemala..” Genome Announc 6, no. 7 (February 15, 2018). https://doi.org/10.1128/genomeA.00024-18.
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  - Clifton, Dana C., Meredith E. Clement, Thomas L. Holland, Gary M. Cox, Kristen V. Dicks, and Jason E. Stout. “Suboptimal HIV Testing Among Patients Admitted With Pneumonia: A Missed Opportunity..” Aids Educ Prev 29, no. 4 (August 2017): 377–88. https://doi.org/10.1521/aeap.2017.29.4.377.
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  - Baker, Arthur W., Sarah S. Lewis, Barbara D. Alexander, Luke F. Chen, Richard J. Wallace, Barbara A. Brown-Elliott, Pamela J. Isaacs, et al. “Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation..” Clin Infect Dis 64, no. 7 (April 1, 2017): 902–11. https://doi.org/10.1093/cid/ciw877.
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  - Stout, Jason E., and Kristen V. Dicks. “A Breath of Fresh Air for Patients with Pulmonary Nontuberculous Mycobacterial Infection..” Am J Respir Crit Care Med 195, no. 6 (March 15, 2017): 716–17. https://doi.org/10.1164/rccm.201610-2073ED.
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  - Oehlers, Stefan H., Mark R. Cronan, Rebecca W. Beerman, Matthew G. Johnson, Jianhua Huang, Christopher D. Kontos, Jason E. Stout, and David M. Tobin. “Infection-Induced Vascular Permeability Aids Mycobacterial Growth..” J Infect Dis 215, no. 5 (March 1, 2017): 813–17. https://doi.org/10.1093/infdis/jiw355.
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  - Woodworth, Michael H., Jennifer L. Saullo, Paul M. Lantos, Gary M. Cox, and Jason E. Stout. “Increasing Nocardia Incidence Associated with Bronchiectasis at a Tertiary Care Center..” Ann Am Thorac Soc 14, no. 3 (March 2017): 347–54. https://doi.org/10.1513/AnnalsATS.201611-907OC.
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  - Collins, Lauren F., Meredith E. Clement, and Jason E. Stout. “Incidence, Long-Term Outcomes, and Healthcare Utilization of Patients With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome and Disseminated Mycobacterium avium Complex From 1992-2015..” Open Forum Infect Dis 4, no. 3 (2017). https://doi.org/10.1093/ofid/ofx120.
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  - Cronan, Mark R., Rebecca W. Beerman, Allison F. Rosenberg, Joseph W. Saelens, Matthew G. Johnson, Stefan H. Oehlers, Dana M. Sisk, et al. “Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection..” Immunity 45, no. 4 (October 18, 2016): 861–76. https://doi.org/10.1016/j.immuni.2016.09.014.
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  - Johnson, M. G., R. W. Bialas, R. P. Hall, and J. E. Stout. “Should all patients undergoing treatment with biologic agents be screened annually for latent tuberculosis infection with an interferon gamma release assay?.” J Dermatolog Treat 27, no. 4 (August 2016): 378–80. https://doi.org/10.3109/09546634.2015.1115815.
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  - Stout, Jason E., and Kristen V. Dicks. “Calculating the economic benefits of what didn't happen..” Int J Tuberc Lung Dis 20, no. 7 (July 2016). https://doi.org/10.5588/ijtld.16.0345.
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  - Holland, D. P., C. D. Hamilton, and J. E. Stout. “Tackling the unknowns of short-course rifapentine-based treatment for active tuberculosis: a decision analysis..” Int J Tuberc Lung Dis 20, no. 6 (June 2016): 827–31. https://doi.org/10.5588/ijtld.15.0006.
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  - Smith, Genee S., Andrew J. Ghio, Jason E. Stout, Kyle P. Messier, Edward E. Hudgens, Mark S. Murphy, Stacy L. Pfaller, Jean-Marie Maillard, and Elizabeth D. Hilborn. “Epidemiology of nontuberculous mycobacteria isolations among central North Carolina residents, 2006-2010..” J Infect 72, no. 6 (June 2016): 678–86. https://doi.org/10.1016/j.jinf.2016.03.008.
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  - Johnson, M. G., J. E. Stout, D. A. Benator, W. C. Whitworth, and D. P. Holland. “Medium matters: modeling the impact of solid medium performance on tuberculosis trial sample size requirements..” Int J Tuberc Lung Dis 20, no. 5 (May 2016): 600–604. https://doi.org/10.5588/ijtld.15.0570.
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  - Samsky, Marc D., Adam D. DeVore, Michael Durkin, Jason E. Stout, Eric J. Velazquez, and Carmelo A. Milano. “Getting to a Man's Heart through His Colon..” Tex Heart Inst J 43, no. 2 (April 2016): 168–70. https://doi.org/10.14503/THIJ-14-4946.
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  - Stout, Jason E., Won-Jung Koh, and Wing Wai Yew. “Update on pulmonary disease due to non-tuberculous mycobacteria..” Int J Infect Dis 45 (April 2016): 123–34. https://doi.org/10.1016/j.ijid.2016.03.006.
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  - Phillips, Patrick P. J., Kelly E. Dooley, Stephen H. Gillespie, Norbert Heinrich, Jason E. Stout, Payam Nahid, Andreas H. Diacon, et al. “A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)..” Bmc Med 14 (March 23, 2016). https://doi.org/10.1186/s12916-016-0597-3.
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  - Bryant, Kia E., Myra G. Allen, Ellen R. Fortenberry, Julie Luffman, Elizabeth Zeringue, and Jason E. Stout. “Association Between Staff Experience and Effective Tuberculosis Contact Tracing in North Carolina, 2008-2009..” N C Med J 77, no. 1 (January 2016): 37–44. https://doi.org/10.18043/ncm.77.1.37.
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  - Johnson, Matthew G., and Jason E. Stout. “Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review..” Infection 43, no. 6 (December 2015): 655–62. https://doi.org/10.1007/s15010-015-0776-8.
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  - Saelens, Joseph W., Dalia Lau-Bonilla, Anneliese Moller, Narda Medina, Brenda Guzmán, Maylena Calderón, Raúl Herrera, et al. “Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak..” Tuberculosis (Edinb) 95, no. 6 (December 2015): 810–16. https://doi.org/10.1016/j.tube.2015.09.001.
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  - Stout, Jason E. “The cost of 'free' tuberculosis care..” Int J Tuberc Lung Dis 19, no. 12 (December 2015). https://doi.org/10.5588/ijtld.15.0818.
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  - Skalski, Linda M., Melissa H. Watt, Jessica C. MacFarlane, Rae Jean Proeschold-Bell, Jason E. Stout, and Kathleen J. Sikkema. “Mental Health and Substance Use Among Patients in a North Carolina HIV Clinic..” N C Med J 76, no. 3 (July 2015): 148–55. https://doi.org/10.18043/ncm.76.3.148.
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  - Lippincott, C. K., M. B. Miller, A. Van Rie, D. J. Weber, A. C. Sena, and J. E. Stout. “The complexities of Xpert® MTB/RIF interpretation..” Int J Tuberc Lung Dis 19, no. 3 (March 2015): 273–75. https://doi.org/10.5588/ijtld.14.0432.
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  - Andrews, Jason R., and Jason E. Stout. “Treating multidrug-resistant tuberculosis in community settings: a wise investment..” Int J Tuberc Lung Dis 19, no. 2 (February 2015). https://doi.org/10.5588/ijtld.14.0761.
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  - Dorman, Susan E., Radojka M. Savic, Stefan Goldberg, Jason E. Stout, Neil Schluger, Grace Muzanyi, John L. Johnson, et al. “Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial..” Am J Respir Crit Care Med 191, no. 3 (February 1, 2015): 333–43. https://doi.org/10.1164/rccm.201410-1843OC.
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  - Stout, Jason E., and Jason R. Andrews. “Isoniazid preventive therapy in medium-incidence settings: the price is right..” Int J Tuberc Lung Dis 18, no. 12 (December 2014). https://doi.org/10.5588/ijtld.14.0760.
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  - Horan, J. L., J. E. Stout, and B. D. Alexander. “Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience..” Transpl Infect Dis 16, no. 5 (October 2014): 859–63. https://doi.org/10.1111/tid.12280.
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  - Koh, W. -. J., J. E. Stout, and W. -. W. Yew. “Advances in the management of pulmonary disease due to Mycobacterium abscessus complex..” Int J Tuberc Lung Dis 18, no. 10 (October 2014): 1141–48. https://doi.org/10.5588/ijtld.14.0134.
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  - Lewis, Sarah S., Gary M. Cox, and Jason E. Stout. “Clinical utility of indium 111-labeled white blood cell scintigraphy for evaluation of suspected infection..” Open Forum Infect Dis 1, no. 2 (September 2014). https://doi.org/10.1093/ofid/ofu089.
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  - Perley, C. C., M. Frahm, E. M. Click, K. M. Dobos, G. Ferrari, J. E. Stout, and R. Frothingham. “The human antibody response to the surface of Mycobacterium tuberculosis.” Plos One 9, no. 6 (June 11, 2014). https://doi.org/10.1371/journal.pone.0098938.
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  - Stout, Jason E. “Understanding the costs of better tuberculosis diagnostics..” Int J Tuberc Lung Dis 18, no. 5 (May 2014). https://doi.org/10.5588/ijtld.14.0211.
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  - Brown-Elliott, B. A., E. Iakhiaeva, D. E. Griffith, G. L. Woods, J. E. Stout, C. R. Wolfe, C. Y. Turenne, and R. J. Wallace. “In Vitro Activity of Amikacin against Isolates of Mycobacterium avium Complex with Proposed MIC Breakpoints and Finding of a 16S rRNA Gene Mutation in Treated Isolates..” Journal of Clinical Microbiology 52, no. 4 (April 2014): 1311–1311. https://doi.org/10.1128/JCM.00224-14.
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  - Reddy, E. A., B. N. Njau, S. C. Morpeth, K. E. Lancaster, A. C. Tribble, V. P. Maro, L. J. Msuya, et al. “A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania.” Bmc Infectious Diseases 14, no. 1 (February 20, 2014). https://doi.org/10.1186/1471-2334-14-89.
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  - Reddy, Elizabeth A., Boniface N. Njau, Susan C. Morpeth, Kathryn E. Lancaster, Alison C. Tribble, Venance P. Maro, Levina J. Msuya, et al. “A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania..” Bmc Infect Dis 14 (February 20, 2014). https://doi.org/10.1186/1471-2334-14-89.
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  - Norton, Brianna L., Corrine I. Voils, Sarah H. Timberlake, Emily J. Hecker, Neela D. Goswami, Kim M. Huffman, Anneka Landgraf, Susanna Naggie, and Jason E. Stout. “Community-based HCV screening: knowledge and attitudes in a high risk urban population..” Bmc Infect Dis 14 (February 10, 2014). https://doi.org/10.1186/1471-2334-14-74.
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  - Norton, Brianna L., Anna K. Person, Catherine Castillo, Christopher Pastrana, Melanie Subramanian, and Jason E. Stout. “Barriers to using text message appointment reminders in an HIV clinic..” Telemed J E Health 20, no. 1 (January 2014): 86–89. https://doi.org/10.1089/tmj.2012.0275.
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  - Perley, Casey C., Marc Frahm, Eva M. Click, Karen M. Dobos, Guido Ferrari, Jason E. Stout, and Richard Frothingham. “The human antibody response to the surface of Mycobacterium tuberculosis..” Plos One 9, no. 2 (2014). https://doi.org/10.1371/journal.pone.0098938.
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  - Philley, J. V., E. Iakhiaeva, R. Vasireddy, S. Vasireddy, B. Brown-Elliott, D. E. Griffith, J. L. Benwill, et al. “Clinical And Laboratory Features Of Respiratory Isolates Of Mycobacterium Chimaera.” American Journal of Respiratory and Critical Care Medicine 189 (January 1, 2014).
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  - Stout, Jason E., Shereen Katrak, Neela D. Goswami, Brianna L. Norton, Ellen R. Fortenberry, Evelyn Foust, and Peter A. Leone. “Integrated screening for tuberculosis and HIV in tuberculosis contact investigations: lessons learned in North Carolina..” Public Health Rep 129 Suppl 1 (January 2014): 21–25. https://doi.org/10.1177/00333549141291S104.
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  - Goswami, Neela D., Jason E. Stout, William C. Miller, Emily J. Hecker, Gary M. Cox, Brianna L. Norton, and Arlene C. Sena. “The footprint of old syphilis: using a reverse screening algorithm for syphilis testing in a U.S. Geographic Information Systems-Based Community Outreach Program..” Sex Transm Dis 40, no. 11 (November 2013): 839–41. https://doi.org/10.1097/OLQ.0000000000000025.
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  - Brown-Elliott, Barbara A., Elena Iakhiaeva, David E. Griffith, Gail L. Woods, Jason E. Stout, Cameron R. Wolfe, Christine Y. Turenne, and Richard J. Wallace. “In vitro activity of amikacin against isolates of Mycobacterium avium complex with proposed MIC breakpoints and finding of a 16S rRNA gene mutation in treated isolates..” J Clin Microbiol 51, no. 10 (October 2013): 3389–94. https://doi.org/10.1128/JCM.01612-13.
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  - Holland, David P., Emily J. Hecker, Ann W. Mosher, and Jason E. Stout. “Translating tuberculosis research into practice: collaboration between academic researchers and public health departments in North Carolina..” N C Med J 74, no. 5 (September 2013): 449–54.
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  - Stout, Jason E. “The race to eliminate tuberculosis..” N C Med J 74, no. 5 (September 2013): 415–19.
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  - Park, P. H., D. P. Holland, A. Wade, N. D. Goswami, D. Bissette, and J. E. Stout. “Public health costs for tuberculosis suspects in Wake County, North Carolina, United States..” Int J Tuberc Lung Dis 17, no. 6 (June 2013): 759–63. https://doi.org/10.5588/ijtld.12.0739.
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  - Culton, Donna A., Anne M. Lachiewicz, Becky A. Miller, Melissa B. Miller, Courteney Mackuen, Pamela Groben, Becky White, Gary M. Cox, and Jason E. Stout. “Nontuberculous mycobacterial infection after fractionated CO(2) laser resurfacing..” Emerg Infect Dis 19, no. 3 (March 2013): 365–70. https://doi.org/10.3201/eid1903.120880.
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  - Stout, Jason E., and R Andres Floto. “Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others..” Am J Respir Crit Care Med 186, no. 9 (November 1, 2012): 822–23. https://doi.org/10.1164/rccm.201208-1500ED.
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  - Dorman, Susan E., Stefan Goldberg, Jason E. Stout, Grace Muzanyi, John L. Johnson, Marc Weiner, Lorna Bozeman, et al. “Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: study 29 of the tuberculosis trials consortium..” J Infect Dis 206, no. 7 (October 1, 2012): 1030–40. https://doi.org/10.1093/infdis/jis461.
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  - Goswami, Neela D., Lara Beth Gadkowski, Carla Piedrahita, Deborah Bissette, Marshall Alex Ahearn, Michela L. M. Blain, Truls Østbye, Jussi Saukkonen, and Jason E. Stout. “Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study..” Bmc Public Health 12 (June 21, 2012). https://doi.org/10.1186/1471-2458-12-468.
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  - Goswami, Neela D., Emily J. Hecker, Carter Vickery, Marshall A. Ahearn, Gary M. Cox, David P. Holland, Susanna Naggie, et al. “Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study..” Plos One 7, no. 10 (2012). https://doi.org/10.1371/journal.pone.0046029.
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  - Holland, David P., Gillian D. Sanders, Carol D. Hamilton, and Jason E. Stout. “Strategies for treating latent multiple-drug resistant tuberculosis: a decision analysis..” Plos One 7, no. 1 (2012). https://doi.org/10.1371/journal.pone.0030194.
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  - Goswami, Neela D., Emily Hecker, David P. Holland, Susanna Naggie, Gary M. Cox, Ann Mosher, Debbie Turner, et al. “Feasibility and willingness-to-pay for integrated community-based tuberculosis testing..” Bmc Infect Dis 11 (November 2, 2011). https://doi.org/10.1186/1471-2334-11-305.
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  - Guderian, L. J., W. C. Miller, A. C. Seña, and J. E. Stout. “Increased prevalence of advanced tuberculosis in rural low tuberculosis caseload counties in North Carolina..” Int J Tuberc Lung Dis 15, no. 11 (November 2011): 1455–i. https://doi.org/10.5588/ijtld.11.0103.
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  - Stout, Jason E., L Beth Gadkowski, Shadia Rath, James A. Alspaugh, Melissa B. Miller, and Gary M. Cox. “Pedicure-associated rapidly growing mycobacterial infection: an endemic disease..” Clin Infect Dis 53, no. 8 (October 2011): 787–92. https://doi.org/10.1093/cid/cir539.
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  - Frahm, Marc, Neela D. Goswami, Kouros Owzar, Emily Hecker, Ann Mosher, Emily Cadogan, Payam Nahid, Guido Ferrari, and Jason E. Stout. “Discriminating between latent and active tuberculosis with multiple biomarker responses..” Tuberculosis (Edinb) 91, no. 3 (May 2011): 250–56. https://doi.org/10.1016/j.tube.2011.02.006.
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  - Holland, D. P., A. K. Person, and J. E. Stout. “Did the 'Great Recession' produce a depression in tuberculosis incidence?.” Int J Tuberc Lung Dis 15, no. 5 (May 2011): 700–702. https://doi.org/10.5588/ijtld.10.0480.
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  - Person, A. K., M. L. M. Blain, H. Jiang, P. W. Rasmussen, and J. E. Stout. “Text messaging for enhancement of testing and treatment for tuberculosis, human immunodeficiency virus, and syphilis: a survey of attitudes toward cellular phones and healthcare..” Telemedicine Journal and E Health : The Official Journal of the American Telemedicine Association 17, no. 3 (April 1, 2011): 189–95.
  - Person, Anna K., Michela L. M. Blain, Helen Jiang, Petra W. Rasmussen, and Jason E. Stout. “Text messaging for enhancement of testing and treatment for tuberculosis, human immunodeficiency virus, and syphilis: a survey of attitudes toward cellular phones and healthcare..” Telemed J E Health 17, no. 3 (April 2011): 189–95. https://doi.org/10.1089/tmj.2010.0164.
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  - Nguyen, L. T., C. D. Hamilton, Q. Xia, and J. E. Stout. “Mortality before or during treatment among tuberculosis patients in North Carolina, 1993-2003..” Int J Tuberc Lung Dis 15, no. 2 (February 2011): 257–i.
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  - Goswami, N. D., L. B. Gadkowski, C. Piedrahita, D. Bissette, M. A. Ahearn, M. L. M. Blain, T. Ostbye, J. Saukkonen, and J. E. Stout. “Predicting Latent Tuberculosis Treatment Initiation And Completion At A Public Health Clinic.” American Journal of Respiratory and Critical Care Medicine 183 (January 1, 2011).
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  - Holland, David P., Gillian D. Sanders, Carol D. Hamilton, and Jason E. Stout. “Potential economic viability of two proposed rifapentine-based regimens for treatment of latent tuberculosis infection..” Plos One 6, no. 7 (2011). https://doi.org/10.1371/journal.pone.0022276.
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  - Griffith, David E., and Jason E. Stout. “It is better to light a candle ... than to repeat the opinions of experts..” Am J Respir Crit Care Med 182, no. 7 (October 1, 2010): 865–66. https://doi.org/10.1164/rccm.201008-1251ED.
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  - Person, Anna K., Neela D. Goswami, Deborah J. Bissette, Debra S. Turner, Ann V. Baker, L Beth Gadkowski, Susanna Naggie, et al. “Pairing QuantiFERON gold in-tube with opt-out HIV testing in a tuberculosis contact investigation in the Southeastern United States..” Aids Patient Care Stds 24, no. 9 (September 2010): 539–43. https://doi.org/10.1089/apc.2010.0102.
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  - Person, A. K., S. M. Chudgar, B. L. Norton, B. C. Tong, and J. E. Stout. “Aspergillus niger: an unusual cause of invasive pulmonary aspergillosis..” J Med Microbiol 59, no. Pt 7 (July 2010): 834–38. https://doi.org/10.1099/jmm.0.018309-0.
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  - Stout, Jason E., and David P. Holland. “Treating latent tuberculosis with rifampin: is it the cheaper option?.” Thorax 65, no. 7 (July 2010): 572–73. https://doi.org/10.1136/thx.2010.138685.
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  - Nahid, Payam, Erin E. Bliven, Elizabeth Y. Kim, William R. Mac Kenzie, Jason E. Stout, Lois Diem, John L. Johnson, et al. “Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis..” Plos One 5, no. 5 (May 20, 2010). https://doi.org/10.1371/journal.pone.0010753.
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  - Stout, Jason E., Andrzej S. Kosinski, Carol Dukes Hamilton, Philip C. Goodman, Ann Mosher, Dick Menzies, Neil Schluger, Awal Khan, John L. Johnson, and John L. Tuberculosis Trials Consortium. “Effect of improving the quality of radiographic interpretation on the ability to predict pulmonary tuberculosis relapse..” Acad Radiol 17, no. 2 (February 2010): 157–62. https://doi.org/10.1016/j.acra.2009.08.013.
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  - Nahid, P., E. E. Bliven, E. Y. Kim, W. R. M. Kenzie, J. E. Stout, L. Diem, J. L. Johnson, S. Gagneux, P. C. Hopewell, and M. Kato-Maeda. “Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis.” Plos One 5, no. 5 (2010). https://doi.org/10.1371/journal.pone.0010753.
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  - Gadkowski, L Beth, Carol D. Hamilton, Myra Allen, Ellen R. Fortenberry, Julie Luffman, Elizabeth Zeringue, and Jason E. Stout. “HIV-specific health care utilization and mortality among tuberculosis/HIV coinfected persons..” Aids Patient Care Stds 23, no. 10 (October 2009): 845–51. https://doi.org/10.1089/apc.2009.0030.
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  - Dorman, Susan E., John L. Johnson, Stefan Goldberg, Grace Muzanye, Nesri Padayatchi, Lorna Bozeman, Charles M. Heilig, et al. “Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis..” Am J Respir Crit Care Med 180, no. 3 (August 1, 2009): 273–80. https://doi.org/10.1164/rccm.200901-0078OC.
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  - Goswami, N. D., J. J. Shah, G. R. Corey, and J. E. Stout. “Short report: Persistent eosinophilia and Strongyloides infection in Montagnard refugees after presumptive albendazole therapy.” American Journal of Tropical Medicine and Hygiene 81, no. 2 (August 1, 2009): 302–4.
  - Goswami, Neela D., J Jina Shah, G Ralph Corey, and Jason E. Stout. “Persistent eosinophilia and Strongyloides infection in Montagnard refugees after presumptive albendazole therapy..” Am J Trop Med Hyg 81, no. 2 (August 2009): 302–4.
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  - Holland, David P., Gillian D. Sanders, Carol D. Hamilton, and Jason E. Stout. “Costs and cost-effectiveness of four treatment regimens for latent tuberculosis infection..” Am J Respir Crit Care Med 179, no. 11 (June 1, 2009): 1055–60. https://doi.org/10.1164/rccm.200901-0153OC.
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  - Fiske, C. T., C. D. Hamilton, and J. E. Stout. “Corrigendum to "Alcohol use and clinical manifestations of tuberculosis" [J Infect 57 (2008) 385-391].” Journal of Infection 58, no. 5 (May 1, 2009). https://doi.org/10.1016/j.jinf.2009.02.016.
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  - Fiske, Christina T., Carol D. Hamilton, and Jason E. Stout. “Alcohol use and clinical manifestations of tuberculosis..” J Infect 58, no. 5 (May 2009): 395–401. https://doi.org/10.1016/j.jinf.2009.02.015.
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  - Holland, David P., Carol D. Hamilton, Amy C. Weintrob, John J. Engemann, Ellen R. Fortenberry, Charles A. Peloquin, and Jason E. Stout. “Therapeutic drug monitoring of antimycobacterial drugs in patients with both tuberculosis and advanced human immunodeficiency virus infection..” Pharmacotherapy 29, no. 5 (May 2009): 503–10. https://doi.org/10.1592/phco.29.5.503.
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  - Connelly, Sarah M., Jane V. Trinh, Melissa D. Johnson, Elizabeth S. Dodds-Ashley, Jason Stout, John J. Engemann, N Deborah Friedman, Donald Kaye, and Keith S. Kaye. “Mortality and time to extubation in severe hospital-acquired pneumonia..” Am J Infect Control 37, no. 2 (March 2009): 143–49. https://doi.org/10.1016/j.ajic.2008.03.011.
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  - Garrigues, Grant E., J Mack Aldridge, Alison P. Toth, and Jason E. Stout. “Nontuberculous mycobacterial olecranon bursitis: case reports and literature review..” J Shoulder Elbow Surg 18, no. 2 (March 2009): e1–5. https://doi.org/10.1016/j.jse.2008.07.009.
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  - Fiske, Christina T., Carol D. Hamilton, and Jason E. Stout. “Alcohol use and clinical manifestations of tuberculosis..” J Infect 57, no. 5 (November 2008): 385–91. https://doi.org/10.1016/j.jinf.2008.08.011.
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  - Hamilton, C. D., J. E. Stout, P. C. Goodman, A. Mosher, R. Menzies, N. W. Schluger, A. Khan, J. L. Johnson, A. N. Vernon, and A. N. Tuberculosis Trials Consortium. “The value of end-of-treatment chest radiograph in predicting pulmonary tuberculosis relapse..” Int J Tuberc Lung Dis 12, no. 9 (September 2008): 1059–64.
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  - Stout, Jason E., Gregory W. Hopkins, Jay R. McDonald, Anita Quinn, Carol D. Hamilton, L Barth Reller, and Richard Frothingham. “Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease..” J Clin Microbiol 46, no. 8 (August 2008): 2790–93. https://doi.org/10.1128/JCM.00719-08.
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  - Stout, Jason E., and Dick Menzies. “Predicting tuberculosis: does the IGRA tell the tale?.” Am J Respir Crit Care Med 177, no. 10 (May 15, 2008): 1055–57. https://doi.org/10.1164/rccm.200802-251ED.
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  - Kipp, Aaron M., Jason E. Stout, Carol Dukes Hamilton, and Annelies Van Rie. “Extrapulmonary tuberculosis, human immunodeficiency virus, and foreign birth in North Carolina, 1993 - 2006..” Bmc Public Health 8 (April 4, 2008). https://doi.org/10.1186/1471-2458-8-107.
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  - Gadkowski, L Beth, and Jason E. Stout. “Cavitary pulmonary disease..” Clin Microbiol Rev 21, no. 2 (April 2008): 305–33. https://doi.org/10.1128/CMR.00060-07.
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  - West, Elizabeth L., Lara Beth Gadkowski, Truls Ostbye, Carla Piedrahita, and Jason E. Stout. “Tuberculosis knowledge, attitudes, and beliefs among North Carolinians at increased risk of infection..” North Carolina Medical Journal 69, no. 1 (January 2008): 14–20.
  - Dukes Hamilton, Carol, Timothy R. Sterling, Henry M. Blumberg, Michael Leonard, James McAuley, David Schlossberg, Jason Stout, and Gwen Huitt. “Extensively drug-resistant tuberculosis: are we learning from history or repeating it?.” Clin Infect Dis 45, no. 3 (August 1, 2007): 338–42. https://doi.org/10.1086/519292.
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  - Tabatabaei, N., J. Stout, P. Goldschmidt-Clermont, and D. Murdoch. “Central nervous system infection and cutaneous lymphadenitis due to Mycobacterium kansasii in an immunocompetent patient..” Infection 35, no. 4 (June 2007): 291–94. https://doi.org/10.1007/s15010-007-6208-7.
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  - Beth Gadkowski, L., and Jason E. Stout. “Pharmacokinetics of rifampicin..” Clin Infect Dis 44, no. 4 (February 15, 2007): 618–19. https://doi.org/10.1086/511081.
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  - Stout, Jason E. “Evaluation and management of patients with pulmonary nontuberculous mycobacterial infections..” Expert Rev Anti Infect Ther 4, no. 6 (December 2006): 981–93. https://doi.org/10.1586/14787210.4.6.981.
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  - Gadkowski, L. B., and J. E. Stout. “Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease.” Infections in Medicine 23, no. 9 (September 1, 2006): 425–33.
  - Stout, J. E., T. Ostbye, E. B. Walter, and C. D. Hamilton. “Tuberculosis knowledge and attitudes among physicians who treat young children in North Carolina, USA..” Int J Tuberc Lung Dis 10, no. 7 (July 2006): 783–88.
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  - Stout, Jason E., Kapil K. Saharia, Savithri Nageswaran, Amina Ahmed, and Carol Dukes Hamilton. “Racial and ethnic disparities in pediatric tuberculosis in North Carolina..” Arch Pediatr Adolesc Med 160, no. 6 (June 2006): 631–37. https://doi.org/10.1001/archpedi.160.6.631.
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  - Hickey, Anthony J., Dongmei Lu, Elizabeth Dodds Ashley, and Jason Stout. “Inhaled azithromycin therapy..” J Aerosol Med 19, no. 1 (2006): 54–60. https://doi.org/10.1089/jam.2006.19.54.
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  - Frothingham, Richard, Jason E. Stout, and Carol Dukes Hamilton. “Current issues in global tuberculosis control..” Int J Infect Dis 9, no. 6 (November 2005): 297–311. https://doi.org/10.1016/j.ijid.2005.04.001.
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  - McDonald, Jay R., N Deborah Friedman, Jason E. Stout, Daniel J. Sexton, and Keith S. Kaye. “Risk factors for ineffective therapy in patients with bloodstream infection..” Arch Intern Med 165, no. 3 (February 14, 2005): 308–13. https://doi.org/10.1001/archinte.165.3.308.
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  - Khuntia, Deepak, and Minesh Mehta. “Motexafin gadolinium: a clinical review of a novel radioenhancer for brain tumors..” Expert Rev Anticancer Ther 4, no. 6 (December 2004): 981–89. https://doi.org/10.1586/14737140.4.6.981.
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  - Stout, Jason E., John J. Engemann, and Carol D. Hamilton. “Tuberculosis transmission from a patient with skin lesions and a negative sputum smear..” N Engl J Med 350, no. 24 (June 10, 2004): 2527–28. https://doi.org/10.1056/NEJM200406103502423.
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  - Stout, Jason E. “Safety of rifampin and pyrazinamide for the treatment of latent tuberculosis infection..” Expert Opin Drug Saf 3, no. 3 (May 2004): 187–98. https://doi.org/10.1517/eods.3.3.187.31073.
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  - Anderson, D. J., D. R. Murdoch, D. J. Sexton, L. B. Reller, J. E. Stout, C. H. Cabell, and G. R. Corey. “Risk factors for infective endocarditis in patients with enterococcal bacteremia: a case-control study..” Infection 32, no. 2 (April 2004): 72–77. https://doi.org/10.1007/s15010-004-2036-1.
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  - Berchuck, A., A. A. Alvarez, and J. E. Stout. “Abdominal pain and bloating in two 20-something patients.” Contemporary Ob/Gyn 48, no. 1 (December 1, 2003): 51–58.
  - Stout, Jason E., John J. Engemann, Allen C. Cheng, Ellen R. Fortenberry, and Carol D. Hamilton. “Safety of 2 months of rifampin and pyrazinamide for treatment of latent tuberculosis..” Am J Respir Crit Care Med 167, no. 6 (March 15, 2003): 824–27. https://doi.org/10.1164/rccm.200209-998OC.
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  - Friedman, N Deborah, Keith S. Kaye, Jason E. Stout, Sarah A. McGarry, Sharon L. Trivette, Jane P. Briggs, Wanda Lamm, et al. “Health care--associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections..” Ann Intern Med 137, no. 10 (November 19, 2002): 791–97. https://doi.org/10.7326/0003-4819-137-10-200211190-00007.
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  - Stout, Jason E., James C. Lai, Julia Giner, and Carol Dukes Hamilton. “Reactivation of retinal toxoplasmosis despite evidence of immune response to highly active antiretroviral therapy..” Clin Infect Dis 35, no. 4 (August 15, 2002): e37–39. https://doi.org/10.1086/341306.
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  - Stout, Jason E., Raoult Ratard, Karen L. Southwick, and Carol Dukes Hamilton. “Epidemiology of human immunodeficiency virus testing among patients with tuberculosis in North Carolina..” South Med J 95, no. 2 (February 2002): 231–38.
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  - Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria..” Infect Control Hosp Epidemiol 22, no. 11 (November 2001): 715–17. https://doi.org/10.1086/501851.
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  - McDonald, J. R., J. E. Stout, S. K. Sharps, and C. D. Hamilton. “Impact of highly active antiretroviral therapy on survival of patients with disseminated Mycobacterium avium in complex disease associated with late-stage human immunodeficiency virus infection.” Clinical Infectious Diseases 33, no. 7 (October 1, 2001): 1219–1219.
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  - Stout, J. E., C. W. Woods, A. A. Alvarez, A. Berchuck, and C. Dukes Hamilton. “Mycobacterium bovis peritonitis mimicking ovarian cancer in a young woman..” Clin Infect Dis 33, no. 4 (August 15, 2001): E14–16. https://doi.org/10.1086/321908.
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  - Stout, J. E., J. R. McDonald, J. J. Engemann, B. D. Alexander, and C. D. Hamilton. “Conditions associated with pulmonary non-tuberculous mycobacteria (NTM) in a tertiary care hospital in the Southeastern US.” Clinical Infectious Diseases 31, no. 1 (July 1, 2000): 311–311.
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  - Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of patients suspected of pulmonary TB in a high incidence area for MOTT..” American Journal of Respiratory and Critical Care Medicine 159, no. 3 (March 1, 1999): A304–A304.
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Teaching & Mentoring
Advising & Mentoring
- Kapil Saharia (Duke medical student): Comentored with Carol Hamilton for MPH thesis, “Racial and ethnic disparities characterize pediatric tuberculosis in North Carolina.” Obtained MPH summer 2003. Currently Assistant Professor, Division of Infectious Diseases, University of Maryland
  
  Lee Ann Morehead (physician assistant student, Wake Forest University): Mentored for Masters’ Research project: “Knowledge of, attitudes to and beliefs about tuberculosis among North Carolinians at increased risk of infection: results from a series of focus groups.” Project presented successfully 5/2005. Currently physician assistant, Department of Dermatology, Duke University Medical Center.
  
  L. Beth Gadkowski (Duke resident/infectious diseases fellow): Comentored with Carol Hamilton. Resident project: “Tuberculosis knowledge, attitudes and beliefs among North Carolinians at increased risk of infection: results from a series of focus groups.” Fellow project examined healthcare utilization and outcomes among persons with TB/HIV in North Carolina. Currently Assistant Professor, Division of Infectious Diseases, Eastern Virginia Medical School.
  
  Aaron Kipp (UNC-Chapel Hill PhD student, epidemiology): Comentored with Carol Hamilton, Annalies VanRie, “Epidemiology of extrapulmonary tuberculosis in North Carolina.” Masters’ thesis, UNC School of Public Health. Currently Assistant Professor, School of Public Health, Vanderbilt University.
  
  Lisa Nguyen (Duke medical student): Comentored with Carol Hamilton for MPH thesis, “Predictors of Mortality among Tuberculosis Patients in North Carolina.” Successfully presented thesis summer 2005. Also precepted in clinic 7/04-7/05. Currently in practice, Mayo Clinic, Scottsdale, AZ.
  
  Christina Fiske (Taulien) (Duke resident): Comentored with Carol Hamilton for resident research project, “A Retrospective Study of the Association Between Alcoholism and Tuberculosis in the United States and North Carolina Between 1994 and 2003.” Currently Assistant Professor of Medicine, Division of Infectious Diseases, Vanderbilt University.
  
  Neela Goswami (Duke resident/infectious diseases fellow): Mentoring for resident research project, Location-based Screenings with Serum Quantiferon-TB Gold In-Tube Compared to Clinic-based Screenings in Detection of Latent TB. Awarded Barton F. Haynes resident research award for this project and Center for AIDS Research small grant award. Currently at the Centers for Disease Control and Prevention, Field Services Branch, Division of Tuberculosis Elimination, Atlanta, GA.
  
  David P. Holland (Duke infectious diseases fellow): Comentored with Carol Hamilton and Gillian Sanders for fellowship research projects, primarily focusing on the use of decision analysis to assist with formulating policies and guidelines for treatment of latent tuberculosis infection and exposures to multi-drug resistant tuberculosis. Also primary mentor for Master’s thesis project, Duke MHS program. Currently Assistant Professor of Medicine, Division of Infectious Diseases, Emory University, Atlanta, GA.
  
  Anna K. Person (Duke infectious diseases fellow): Research mentor for fellowship project: Text messaging to Enhance Testing and Treatment for Tuberculosis, HIV, and Syphilis (TEXTT THIS). Currently Assistant Professor of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN.
  
  Laura Guderian (UNC-Chapel Hill infectious diseases fellow/preventive medicine resident). Comentoring with Arlene Sena and William Miller, project: Association between rural location and tuberculosis presentation in North Carolina. Currently in private practice at One Medical Group, New York, NY.
  
  Kia Armstrong (CDC Public Health Prevention Specialist). Comentored with Maureen O’Rourke, project: Association between staff experience and effective tuberculosis contact tracing, North Carolina, 2008–2009. Currently working for Centers for Disease Control and Prevention, Division of Tuberculosis Elimination.
  
  Paul Park (Duke medical resident). Clinical mentor, subspecialty clinic (TB clinic), and research mentor for resident project: Costs of nontuberculous mycobacterial infections to a public health tuberculosis clinic. Awarded a Duke Resident Research Award to conduct this project. Currently employed by Partners in Health.
  
  Brianna Norton (Duke infectious diseases fellow). Comentored with Susanna Naggie, “Acceptability of Community-Based Hepatitis C Testing in Wake County, North Carolina.” Currently Assistant Professor, Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY.
  
  Charles McCormick (Duke medicine-psychiatry resident). Clinical mentor, subspecialty clinic (TB clinic) and research mentor for resident project: Tobacco use, tuberculosis infection, and comorbidities among tuberculosis clinic attendees in Wake County, North Carolina. Currently in private practice in Raleigh, NC.
  
  Michael Woodworth (Duke medicine resident). 2013-2015. Research mentor for resident project: Nocardia at Duke University Medical Center 1996-2013. Awarded a Duke Resident Research Award to conduct this project. Currently infectious diseases fellow, Emory University, Atlanta, GA.
  
  Matthew Johnson (Duke infectious diseases fellow). “Xpert MTB/RIF testing among HIV-positive patients in Zambia”, mentor during research years of fellowship, 7/2014-6/2016. Currently at Merck.
  
  Dana Clifton (Duke medicine/pediatrics resident). Research mentor for resident project: HIV testing among pneumonia patients at Duke. Awarded a Duke Resident Research Award to conduct this project. Currently hospitalist, Duke University Medical Center.
  
  Lauren Collins (Duke medicine resident). Research mentor for resident project: Long term outcomes of patients with AIDS and disseminated Mycobacterium avium intracellulare. Awarded a Duke Resident Research Award to conduct this project. Currently infectious diseases fellow, Emory University, Atlanta, GA.

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

Leadership & Clinical Positions at Duke

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Academic Articles

Advising & Mentoring