Jason Eric Stout | Scholars@Duke

Jason Eric Stout
Professor of Medicine

My research focuses on the epidemiology, natural history, and treatment of tuberculosis and nontuberculous mycobacterial infections. I am also interested in the impact of HIV infection on mycobacterial infection and disease, and in examining health disparities as they relate to infectious diseases, particularly in immigrant populations.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Infectious Diseases, Medicine 2017

Contact Information

181 Hanes House, Durham, NC 27710
Duke Box 102359, Durham, NC 27710
stout002@mc.duke.edu (919) 668-0826

Background
Education, Training, & Certifications
- Fellow in Infectious Diseases, Medicine, Duke University 1999 - 2002
- Medical Resident, Medicine, Duke University 1996 - 1999
- M.D., SUNY Upstate Medical University 1996
Duke Appointment History
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2013 - 2017
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2013
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2004 - 2010
- Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2004
Leadership & Clinical Positions at Duke
- Medical Director, Adult Infectious Diseases Clinic, 1/2008-1/2018
  Vice Chief for Clinical Affairs, Division of Infectious Diseases, 1/2008-1/2018
Recognition
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Macrophage Reprogramming During Granuloma Formation in the Zebrafish awarded by National Institutes of Health 2017 - 2022
- Genetic dissection of angiogenesis in the tuberculous granuloma awarded by National Institutes of Health 2017 - 2022
- Prospective Comparison of the Tuberculin Skin Test (TST) vs. Interferon Gamma Release Assays (IGRAs) in Diagnosing Laten awarded by Centers for Disease Control and Prevention 2011 - 2021
- The Genetic Basis of Bone Disease in Mycobacterial Infection awarded by National Institutes of Health 2017 - 2021
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- Prospective Comparison of the Tuberculin Skin Test (TST) vs. Interferon Gamma Release Assays (IGRAs) in Diagnosing Laten awarded by Centers for Disease Control and Prevention 2011 - 2019
- Epidemiology/General Communicable Disease Control awarded by NC Department of Health and Human Services 2018
- Tuberculosis Trial Consortium awarded by FHI 360 2015 - 2018
- Epidemiology/General Communicable Disease Control awarded by NC Department of Health and Human Services 2017
- The Genetic Basis of Bone Disease in Mycobacterial Infection awarded by National Institutes of Health 2014 - 2017
- Role of Developmental Signaling Pathways in Tuberculosis Pathogenesis awarded by National Institutes of Health 2017
- Tuberculosis Trial Consortium awarded by Family Health International 2009 - 2014
- Mathematical Modeling in Clinical Trials of Tuberculosis Therapeutics awarded by National Institutes of Health 2009 - 2014
- Large Scale Antibody and TCell Epitope Discovery awarded by National Institutes of Health 2004 - 2011
- Role of non-tuberculous mycobacteria in lung disease awarded by National Institutes of Health 2003 - 2008
Publications & Artistic Works
Selected Publications
- Journal Articles
  - Stout, JE, Wu, Y, Ho, CS, Pettit, AC, Feng, P-J, Katz, DJ, Ghosh, S, Venkatappa, T, Luo, R, and Tuberculosis Epidemiologic Studies Consortium, . "Evaluating latent tuberculosis infection diagnostics using latent class analysis." Thorax 73, no. 11 (November 2018): 1062-1070. Full Text
  - Dicks, KV, Holland, DP, Allen, MG, Fortenberry, ER, Luffman, J, Zeringue, E, Wheeler, J, and Stout, JE. "Impact of radiology reports on timely tuberculosis diagnosis." Postgraduate Medical Journal 94, no. 1115 (September 19, 2018): 495-498. Full Text
  - Dicks, KV, and Stout, JE. "Molecular Diagnostics for Mycobacterium tuberculosis Infection." Annual Review of Medicine (August 20, 2018). Full Text
  - Hemmersbach-Miller, M, Stout, JE, Woodworth, MH, Cox, GM, and Saullo, JL. "Nocardia infections in the transplanted host." Transplant Infectious Disease : an Official Journal of the Transplantation Society 20, no. 4 (August 2018): e12902-null. Full Text
  - Rinsky, JL, Farmer, D, Dixon, J, Maillard, J-M, Young, T, Stout, J, Ahmed, A, Fleischauer, A, MacFarquhar, J, and Moore, Z. "Notes from the Field: Contact Investigation for an Infant with Congenital Tuberculosis Infection — North Carolina, 2016." Mmwr. Morbidity and Mortality Weekly Report 67, no. 23 (June 15, 2018): 670-671. Full Text
  - Johnson, DF, and Stout, JE. "Corticosteroids for tuberculous pericarditis: can we learn from variability?." The International Journal of Tuberculosis and Lung Disease 22, no. 5 (May 2018): 475-null. Full Text
  - Okeke, NL, Clement, ME, McKellar, MS, and Stout, JE. "Health Care Utilization Behaviors Predict Disengagement From HIV Care: A Latent Class Analysis." Open Forum Infectious Diseases 5, no. 5 (May 2018): ofy088-null. Full Text
  - Stout, JE, Belknap, R, Wu, Y-J, and Ho, CS. "Paradox of serial interferon-gamma release assays: variability width more important than specificity size." The International Journal of Tuberculosis and Lung Disease 22, no. 5 (May 2018): 518-523. Full Text
  - van Ingen, J, Aksamit, T, Andrejak, C, Böttger, EC, Cambau, E, Daley, CL, Griffith, DE, Guglielmetti, L, Holland, SM, Huitt, GA, Koh, W-J, Lange, C, Leitman, P, Marras, TK, Morimoto, K, Olivier, KN, Santin, M, Stout, JE, Thomson, R, Tortoli, E, Wallace, RJ, Winthrop, KL, Wagner, D, and for NTM-NET, . "Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement." The European Respiratory Journal 51, no. 3 (March 22, 2018). Full Text
  - Saelens, JW, Lau-Bonilla, D, Moller, A, Xet-Mull, AM, Medina, N, Guzmán, B, Calderón, M, Herrera, R, Stout, JE, Arathoon, E, Samayoa, B, and Tobin, DM. "Annotated Genome Sequences of 16 Lineage 4 Mycobacterium tuberculosis Strains from Guatemala." Genome Announcements 6, no. 7 (February 15, 2018). Full Text
  - Clifton, DC, Clement, ME, Holland, TL, Cox, GM, Dicks, KV, and Stout, JE. "Suboptimal HIV Testing Among Patients Admitted With Pneumonia: A Missed Opportunity." AIDS education and prevention : official publication of the International Society for AIDS Education 29, no. 4 (August 2017): 377-388. Full Text
  - Baker, AW, Lewis, SS, Alexander, BD, Chen, LF, Wallace, RJ, Brown-Elliott, BA, Isaacs, PJ, Pickett, LC, Patel, CB, Smith, PK, Reynolds, JM, Engel, J, Wolfe, CR, Milano, CA, Schroder, JN, Davis, RD, Hartwig, MG, Stout, JE, Strittholt, N, Maziarz, EK, Saullo, JH, Hazen, KC, Walczak, RJ, Vasireddy, R, Vasireddy, S, McKnight, CM, Anderson, DJ, and Sexton, DJ. "Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 64, no. 7 (April 2017): 902-911. Full Text
  - Oehlers, SH, Cronan, MR, Beerman, RW, Johnson, MG, Huang, J, Kontos, CD, Stout, JE, and Tobin, DM. "Infection-Induced Vascular Permeability Aids Mycobacterial Growth." The Journal of Infectious Diseases 215, no. 5 (March 2017): 813-817. Full Text
  - Stout, JE, and Dicks, KV. "A Breath of Fresh Air for Patients with Pulmonary Nontuberculous Mycobacterial Infection." American journal of respiratory and critical care medicine 195, no. 6 (March 2017): 716-717. Full Text
  - Woodworth, MH, Saullo, JL, Lantos, PM, Cox, GM, and Stout, JE. "Increasing Nocardia Incidence Associated with Bronchiectasis at a Tertiary Care Center." Annals of the American Thoracic Society 14, no. 3 (March 2017): 347-354. Full Text
  - Collins, LF, Clement, ME, and Stout, JE. "Incidence, Long-Term Outcomes, and Healthcare Utilization of Patients With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome and Disseminated Mycobacterium avium Complex From 1992-2015." Open forum infectious diseases 4, no. 3 (January 2017): ofx120-. Full Text Open Access Copy
  - Cronan, MR, Beerman, RW, Rosenberg, AF, Saelens, JW, Johnson, MG, Oehlers, SH, Sisk, DM, Jurcic Smith, KL, Medvitz, NA, Miller, SE, Trinh, LA, Fraser, SE, Madden, JF, Turner, J, Stout, JE, Lee, S, and Tobin, DM. "Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection." Immunity 45, no. 4 (October 2016): 861-876. Full Text
  - Johnson, MG, Bialas, RW, Hall, RP, and Stout, JE. "Should all patients undergoing treatment with biologic agents be screened annually for latent tuberculosis infection with an interferon gamma release assay?." The Journal of Dermatological Treatment 27, no. 4 (August 2016): 378-380. Full Text
  - Stout, JE, and Dicks, KV. "Calculating the economic benefits of what didn't happen." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20, no. 7 (July 2016): 854-. Full Text
  - Holland, DP, Hamilton, CD, and Stout, JE. "Tackling the unknowns of short-course rifapentine-based treatment for active tuberculosis: a decision analysis." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20, no. 6 (June 2016): 827-831. Full Text
  - Smith, GS, Ghio, AJ, Stout, JE, Messier, KP, Hudgens, EE, Murphy, MS, Pfaller, SL, Maillard, J-M, and Hilborn, ED. "Epidemiology of nontuberculous mycobacteria isolations among central North Carolina residents, 2006-2010." The Journal of Infection 72, no. 6 (June 2016): 678-686. Full Text
  - Johnson, MG, Stout, JE, Benator, DA, Whitworth, WC, and Holland, DP. "Medium matters: modeling the impact of solid medium performance on tuberculosis trial sample size requirements." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20, no. 5 (May 2016): 600-604. Full Text
  - Samsky, MD, DeVore, AD, Durkin, M, Stout, JE, Velazquez, EJ, and Milano, CA. "Getting to a Man's Heart through His Colon." Texas Heart Institute Journal 43, no. 2 (April 2016): 168-170. Full Text
  - Stout, JE, Koh, W-J, and Yew, WW. "Update on pulmonary disease due to non-tuberculous mycobacteria." International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases 45 (April 2016): 123-134. (Review) Full Text
  - Phillips, PPJ, Dooley, KE, Gillespie, SH, Heinrich, N, Stout, JE, Nahid, P, Diacon, AH, Aarnoutse, RE, Kibiki, GS, Boeree, MJ, and Hoelscher, M. "A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)." BMC medicine 14 (March 23, 2016): 51-. Full Text Open Access Copy
  - Bryant, KE, Allen, MG, Fortenberry, ER, Luffman, J, Zeringue, E, and Stout, JE. "Association Between Staff Experience and Effective Tuberculosis Contact Tracing in North Carolina, 2008-2009." N C Med J 77, no. 1 (January 2016): 37-44. Full Text Link to Item
  - Johnson, MG, and Stout, JE. "Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review." Infection 43, no. 6 (December 2015): 655-662. (Review) Full Text
  - Saelens, JW, Lau-Bonilla, D, Moller, A, Medina, N, Guzmán, B, Calderón, M, Herrera, R, Sisk, DM, Xet-Mull, AM, Stout, JE, Arathoon, E, Samayoa, B, and Tobin, DM. "Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak." Tuberculosis (Edinb) 95, no. 6 (December 2015): 810-816. Full Text Open Access Copy Link to Item
  - Stout, JE. "The cost of 'free' tuberculosis care." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 19, no. 12 (December 2015): 1413-. Full Text
  - Skalski, LM, Watt, MH, MacFarlane, JC, Proeschold-Bell, RJ, Stout, JE, and Sikkema, KJ. "Mental Health and Substance Use Among Patients in a North Carolina HIV Clinic." N C Med J 76, no. 3 (July 2015): 148-155. Full Text Open Access Copy Link to Item
  - Lippincott, CK, Miller, MB, Van Rie, A, Weber, DJ, Sena, AC, and Stout, JE. "The complexities of Xpert® MTB/RIF interpretation." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 19, no. 3 (March 2015): 273-275. Full Text
  - Andrews, JR, and Stout, JE. "Treating multidrug-resistant tuberculosis in community settings: a wise investment." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 19, no. 2 (February 2015): 127-. Full Text
  - Dorman, SE, Savic, RM, Goldberg, S, Stout, JE, Schluger, N, Muzanyi, G, Johnson, JL, Nahid, P, Hecker, EJ, Heilig, CM, Bozeman, L, Feng, P-JI, Moro, RN, MacKenzie, W, Dooley, KE, Nuermberger, EL, Vernon, A, Weiner, M, and Tuberculosis Trials Consortium, . "Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial." American Journal of Respiratory and Critical Care Medicine 191, no. 3 (February 2015): 333-343. Full Text
  - Stout, JE, and Andrews, JR. "Isoniazid preventive therapy in medium-incidence settings: the price is right." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 18, no. 12 (December 2014): 1388-. Full Text
  - Horan, JL, Stout, JE, and Alexander, BD. "Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience." Transplant infectious disease : an official journal of the Transplantation Society 16, no. 5 (October 2014): 859-863. Full Text
  - Horan, JL, Stout, JE, and Alexander, BD. "Hepatitis B core antibody-positive donors in cardiac transplantation: A single-center experience." Transplant Infectious Disease 16, no. 5 (October 1, 2014): 859-863. Full Text
  - Koh, W-J, Stout, JE, and Yew, W-W. "Advances in the management of pulmonary disease due to Mycobacterium abscessus complex." The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease 18, no. 10 (October 2014): 1141-1148. (Review) Full Text
  - Lewis, SS, Cox, GM, and Stout, JE. "Clinical utility of indium 111-labeled white blood cell scintigraphy for evaluation of suspected infection." Open Forum Infectious Diseases 1, no. 2 (September 17, 2014): ofu089-null. Full Text Open Access Copy
  - Perley, CC, Frahm, M, Click, EM, Dobos, KM, Ferrari, G, Stout, JE, and Frothingham, R. "The human antibody response to the surface of Mycobacterium tuberculosis." Plos One 9, no. 6 (June 11, 2014). Full Text
  - Stout, JE. "Understanding the costs of better tuberculosis diagnostics." The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 18, no. 5 (May 2014): 508-. Full Text
  - Brown-Elliott, BA, Iakhiaeva, E, Griffith, DE, Woods, GL, Stout, JE, Wolfe, CR, Turenne, CY, and Wallace, RJ. "In Vitro Activity of Amikacin against Isolates of Mycobacterium avium Complex with Proposed MIC Breakpoints and Finding of a 16S rRNA Gene Mutation in Treated Isolates." Journal of Clinical Microbiology 52, no. 4 (April 2014): 1311-1311. Full Text
  - Brown-Elliott, BA, Iakhiaeva, E, Griffith, DE, Woods, GL, Stout, JE, Wolfe, CR, Turenne, CY, and Wallace, RJ. "In Vitro Activity of Amikacin against Isolates of Mycobacterium avium Complex with Proposed MIC Breakpoints and Finding of a 16S rRNA Gene Mutation in Treated Isolates." Journal of Clinical Microbiology 52, no. 4 (April 1, 2014): 1311-1311. Full Text
  - Reddy, EA, Njau, BN, Morpeth, SC, Lancaster, KE, Tribble, AC, Maro, VP, Msuya, LJ, Morrissey, AB, Kibiki, GS, Thielman, NM, Cunningham, CK, Schimana, W, Shao, JF, Chow, S-C, Stout, JE, Crump, JA, Bartlett, JA, and Hamilton, CD. "A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania." BMC infectious diseases 14 (February 20, 2014): 89-. Full Text Open Access Copy
  - Reddy, EA, Njau, BN, Morpeth, SC, Lancaster, KE, Tribble, AC, Maro, VP, Msuya, LJ, Morrissey, AB, Kibiki, GS, Thielman, NM, Cunningham, CK, Schimana, W, Shao, JF, Chow, SC, Stout, JE, Crump, JA, Bartlett, JA, and Hamilton, CD. "A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania." Bmc Infectious Diseases 14, no. 1 (February 20, 2014). Full Text
  - Norton, BL, Voils, CI, Timberlake, SH, Hecker, EJ, Goswami, ND, Huffman, KM, Landgraf, A, Naggie, S, and Stout, JE. "Community-based HCV screening: knowledge and attitudes in a high risk urban population." BMC infectious diseases 14 (February 10, 2014): 74-. Full Text Open Access Copy
  - Norton, BL, Person, AK, Castillo, C, Pastrana, C, Subramanian, M, and Stout, JE. "Barriers to using text message appointment reminders in an HIV clinic." Telemed J E Health 20, no. 1 (January 2014): 86-89. Full Text Link to Item
  - Perley, CC, Frahm, M, Click, EM, Dobos, KM, Ferrari, G, Stout, JE, and Frothingham, R. "The human antibody response to the surface of Mycobacterium tuberculosis." Plos One 9, no. 2 (January 2014): e98938-null. Full Text Open Access Copy
  - Philley, JV, Iakhiaeva, E, Vasireddy, R, Vasireddy, S, Brown-Elliott, B, Griffith, DE, Benwill, JL, McNulty, S, Stout, JE, Falkinham, JO, Williams, MD, Turenne, C, and Wallace, RJ. "Clinical And Laboratory Features Of Respiratory Isolates Of Mycobacterium Chimaera." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 189 (2014). Link to Item
  - Stout, JE, Katrak, S, Goswami, ND, Norton, BL, Fortenberry, ER, Foust, E, and Leone, PA. "Integrated screening for tuberculosis and HIV in tuberculosis contact investigations: lessons learned in North Carolina." Public Health Reports (Washington, D.C. : 1974) 129 Suppl 1 (January 2014): 21-25. Full Text
  - Goswami, ND, Stout, JE, Miller, WC, Hecker, EJ, Cox, GM, Norton, BL, and Sena, AC. "The footprint of old syphilis: using a reverse screening algorithm for syphilis testing in a U.S. Geographic Information Systems-Based Community Outreach Program." Sexually Transmitted Diseases 40, no. 11 (November 2013): 839-841. Full Text
  - Brown-Elliott, BA, Iakhiaeva, E, Griffith, DE, Woods, GL, Stout, JE, Wolfe, CR, Turenne, CY, and Wallace, RJ. "In vitro activity of amikacin against isolates of Mycobacterium avium complex with proposed MIC breakpoints and finding of a 16S rRNA gene mutation in treated isolates." Journal of Clinical Microbiology 51, no. 10 (October 2013): 3389-3394. Full Text
  - Holland, DP, Hecker, EJ, Mosher, AW, and Stout, JE. "Translating tuberculosis research into practice: collaboration between academic researchers and public health departments in North Carolina." N C Med J 74, no. 5 (September 2013): 449-454. Link to Item
  - Stout, JE. "The race to eliminate tuberculosis." N C Med J 74, no. 5 (September 2013): 415-419. Link to Item
  - Park, PH, Holland, DP, Wade, A, Goswami, ND, Bissette, D, and Stout, JE. "Public health costs for tuberculosis suspects in Wake County, North Carolina, United States." Int J Tuberc Lung Dis 17, no. 6 (June 2013): 759-763. Full Text Link to Item
  - Culton, DA, Lachiewicz, AM, Miller, BA, Miller, MB, Mackuen, C, Groben, P, White, B, Cox, GM, and Stout, JE. "Nontuberculous mycobacterial infection after fractionated CO(2) laser resurfacing." Emerg Infect Dis 19, no. 3 (March 2013): 365-370. Full Text Open Access Copy Link to Item
  - Stout, JE, and Floto, RA. "Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others." American Journal of Respiratory and Critical Care Medicine 186, no. 9 (November 2012): 822-823. Full Text
  - Dorman, SE, Goldberg, S, Stout, JE, Muzanyi, G, Johnson, JL, Weiner, M, Bozeman, L, Heilig, CM, Feng, P-J, Moro, R, Narita, M, Nahid, P, Ray, S, Bates, E, Haile, B, Nuermberger, EL, Vernon, A, Schluger, NW, and Tuberculosis Trials Consortium, . "Substitution of rifapentine for rifampin during intensive phase treatment of pulmonary tuberculosis: study 29 of the tuberculosis trials consortium." The Journal of Infectious Diseases 206, no. 7 (October 2012): 1030-1040. Full Text
  - Holland, DP, Sanders, GD, Hamilton, CD, and Stout, JE. "Strategies for treating latent multiple-drug resistant tuberculosis: a decision analysis." Plos One 7, no. 1 (January 17, 2012): e30194-null. Full Text Open Access Copy
  - Goswami, ND, Gadkowski, LB, Piedrahita, C, Bissette, D, Ahearn, MA, Blain, MLM, Østbye, T, Saukkonen, J, and Stout, JE. "Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study." Bmc Public Health 12 (January 2012): 468-null. Full Text Open Access Copy
  - Goswami, ND, Hecker, EJ, Vickery, C, Ahearn, MA, Cox, GM, Holland, DP, Naggie, S, Piedrahita, C, Mosher, A, Torres, Y, Norton, BL, Suchindran, S, Park, PH, Turner, D, and Stout, JE. "Geographic information system-based screening for TB, HIV, and syphilis (GIS-THIS): a cross-sectional study." PLoS One 7, no. 10 (2012): e46029-. Full Text Open Access Copy Link to Item
  - Goswami, ND, Hecker, E, Holland, DP, Naggie, S, Cox, GM, Mosher, A, Turner, D, Torres, Y, Vickery, C, Ahearn, MA, Blain, MLM, Rasmussen, P, and Stout, JE. "Feasibility and willingness-to-pay for integrated community-based tuberculosis testing. (Published online)" BMC Infect Dis 11 (November 2, 2011): 305-. Full Text Open Access Copy Link to Item
  - Stout, JE, Gadkowski, LB, Rath, S, Alspaugh, JA, Miller, MB, and Cox, GM. "Pedicure-associated rapidly growing mycobacterial infection: an endemic disease." Clin Infect Dis 53, no. 8 (October 2011): 787-792. Full Text Link to Item
  - Frahm, M, Goswami, ND, Owzar, K, Hecker, E, Mosher, A, Cadogan, E, Nahid, P, Ferrari, G, and Stout, JE. "Discriminating between latent and active tuberculosis with multiple biomarker responses." Tuberculosis (Edinburgh, Scotland) 91, no. 3 (May 2011): 250-256. Full Text
  - Holland, DP, Person, AK, and Stout, JE. "Did the 'Great Recession' produce a depression in tuberculosis incidence?." The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease 15, no. 5 (May 2011): 700-702. Full Text
  - Person, AK, Blain, MLM, Jiang, H, Rasmussen, PW, and Stout, JE. "Text messaging for enhancement of testing and treatment for tuberculosis, human immunodeficiency virus, and syphilis: a survey of attitudes toward cellular phones and healthcare." Telemed J E Health 17, no. 3 (April 2011): 189-195. Full Text Link to Item
  - Nguyen, LT, Hamilton, CD, Xia, Q, and Stout, JE. "Mortality before or during treatment among tuberculosis patients in North Carolina, 1993-2003." Int J Tuberc Lung Dis 15, no. 2 (February 2011): 257-i. Link to Item
  - Goswami, ND, Gadkowski, LB, Piedrahita, C, Bissette, D, Ahearn, MA, Blain, MLM, Ostbye, T, Saukkonen, J, and Stout, JE. "Predicting Latent Tuberculosis Treatment Initiation And Completion At A Public Health Clinic." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 183 (2011). Link to Item
  - Guderian, LJ, Miller, WC, Seña, AC, and Stout, JE. "Increased prevalence of advanced tuberculosis in rural low tuberculosis caseload counties in North Carolina." International Journal of Tuberculosis and Lung Disease 15, no. 11 (2011): 1455-1460. Full Text
  - Holland, DP, Sanders, GD, Hamilton, CD, and Stout, JE. "Potential economic viability of two proposed rifapentine-based regimens for treatment of latent tuberculosis infection." PLoS One 6, no. 7 (2011): e22276-. Full Text Open Access Copy Link to Item
  - Person, AK, Blain, MLM, Jiang, H, Rasmussen, PW, and Stout, JE. "Text messaging for enhancement of testing and treatment for tuberculosis, human immunodeficiency virus, and syphilis: A survey of attitudes toward cellular phones and healthcare." Telemedicine and e-Health 17, no. 3 (2011): 189-195. Full Text
  - Griffith, DE, and Stout, JE. "It is better to light a candle .. than to repeat the opinions of experts." Am J Respir Crit Care Med 182, no. 7 (October 1, 2010): 865-866. Full Text Link to Item
  - Person, AK, Goswami, ND, Bissette, DJ, Turner, DS, Baker, AV, Gadkowski, LB, Naggie, S, Erlandson, K, Chen, L, Lalani, T, Cox, GM, and Stout, JE. "Pairing QuantiFERON gold in-tube with opt-out HIV testing in a tuberculosis contact investigation in the Southeastern United States." Aids Patient Care and Stds 24, no. 9 (September 2010): 539-543. Full Text Open Access Copy
  - Person, AK, Chudgar, SM, Norton, BL, Tong, BC, and Stout, JE. "Aspergillus niger: an unusual cause of invasive pulmonary aspergillosis." Journal of Medical Microbiology 59, no. Pt 7 (July 2010): 834-838. Full Text Open Access Copy
  - Stout, JE, and Holland, DP. "Treating latent tuberculosis with rifampin: is it the cheaper option?." Thorax 65, no. 7 (July 2010): 572-573. Full Text Link to Item
  - Nahid, P, Bliven, EE, Kim, EY, Mac Kenzie, WR, Stout, JE, Diem, L, Johnson, JL, Gagneux, S, Hopewell, PC, Kato-Maeda, M, and Tuberculosis Trials Consortium, . "Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis. (Published online)" PLoS One 5, no. 5 (May 20, 2010): e10753-. Full Text Open Access Copy Link to Item
  - Stout, JE, Kosinski, AS, Hamilton, CD, Goodman, PC, Mosher, A, Menzies, D, Schluger, N, Khan, A, Johnson, JL, and Tuberculosis Trials Consortium, . "Effect of improving the quality of radiographic interpretation on the ability to predict pulmonary tuberculosis relapse." Acad Radiol 17, no. 2 (February 2010): 157-162. Full Text Link to Item
  - Nahid, P, Bliven, EE, Kim, EY, Kenzie, WRM, Stout, JE, Diem, L, Johnson, JL, Gagneux, S, Hopewell, PC, and Kato-Maeda, M. "Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis." PLoS ONE 5, no. 5 (2010). Full Text
  - Gadkowski, LB, Hamilton, CD, Allen, M, Fortenberry, ER, Luffman, J, Zeringue, E, and Stout, JE. "HIV-specific health care utilization and mortality among tuberculosis/HIV coinfected persons." Aids Patient Care and Stds 23, no. 10 (October 2009): 845-851. Full Text
  - Dorman, SE, Johnson, JL, Goldberg, S, Muzanye, G, Padayatchi, N, Bozeman, L, Heilig, CM, Bernardo, J, Choudhri, S, Grosset, JH, Guy, E, Guyadeen, P, Leus, MC, Maltas, G, Menzies, D, Nuermberger, EL, Villarino, M, Vernon, A, Chaisson, RE, and Tuberculosis Trials Consortium, . "Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis." American Journal of Respiratory and Critical Care Medicine 180, no. 3 (August 2009): 273-280. Full Text
  - Goswami, ND, Shah, JJ, Corey, GR, and Stout, JE. "Persistent eosinophilia and Strongyloides infection in Montagnard refugees after presumptive albendazole therapy." The American Journal of Tropical Medicine and Hygiene 81, no. 2 (August 2009): 302-304. Full Text
  - Holland, DP, Sanders, GD, Hamilton, CD, and Stout, JE. "Costs and cost-effectiveness of four treatment regimens for latent tuberculosis infection." American Journal of Respiratory and Critical Care Medicine 179, no. 11 (June 2009): 1055-1060. Full Text
  - Fiske, CT, Hamilton, CD, and Stout, JE. "Alcohol use and clinical manifestations of tuberculosis." J Infect 58, no. 5 (May 2009): 395-401. Link to Item
  - Holland, DP, Hamilton, CD, Weintrob, AC, Engemann, JJ, Fortenberry, ER, Peloquin, CA, and Stout, JE. "Therapeutic drug monitoring of antimycobacterial drugs in patients with both tuberculosis and advanced human immunodeficiency virus infection." Pharmacotherapy 29, no. 5 (May 2009): 503-510. Full Text Link to Item
  - Connelly, SM, Trinh, JV, Johnson, MD, Dodds-Ashley, ES, Stout, J, Engemann, JJ, Friedman, ND, Kaye, D, and Kaye, KS. "Mortality and time to extubation in severe hospital-acquired pneumonia." Am J Infect Control 37, no. 2 (March 2009): 143-149. Full Text Link to Item
  - Garrigues, GE, Aldridge, JM, Toth, AP, and Stout, JE. "Nontuberculous mycobacterial olecranon bursitis: case reports and literature review." J Shoulder Elbow Surg 18, no. 2 (March 2009): e1-e5. Full Text Link to Item
  - Fiske, CT, Hamilton, CD, and Stout, JE. "Alcohol use and clinical manifestations of tuberculosis (DOI:10.1016/j.jinf.2008.08.011)." Journal of Infection 58, no. 5 (2009): 395-401. Full Text
  - Fiske, CT, Hamilton, CD, and Stout, JE. "Corrigendum to "Alcohol use and clinical manifestations of tuberculosis" [J Infect 57 (2008) 385-391]." Journal of Infection 58, no. 5 (2009): 394--. Full Text
  - Goswami, ND, Shah, JJ, Corey, GR, and Stout, JE. "Short report: Persistent eosinophilia and Strongyloides infection in Montagnard refugees after presumptive albendazole therapy." American Journal of Tropical Medicine and Hygiene 81, no. 2 (2009): 302-304.
  - Fiske, CT, Hamilton, CD, and Stout, JE. "Alcohol use and clinical manifestations of tuberculosis." J Infect 57, no. 5 (November 2008): 385-391. Full Text Link to Item
  - Hamilton, CD, Stout, JE, Goodman, PC, Mosher, A, Menzies, R, Schluger, NW, Khan, A, Johnson, JL, Vernon, AN, and Tuberculosis Trials Consortium, . "The value of end-of-treatment chest radiograph in predicting pulmonary tuberculosis relapse." Int J Tuberc Lung Dis 12, no. 9 (September 2008): 1059-1064. Link to Item
  - Stout, JE, Hopkins, GW, McDonald, JR, Quinn, A, Hamilton, CD, Reller, LB, and Frothingham, R. "Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease." Journal of Clinical Microbiology 46, no. 8 (August 2008): 2790-2793. Full Text
  - Stout, JE, and Menzies, D. "Predicting tuberculosis: does the IGRA tell the tale?." Am J Respir Crit Care Med 177, no. 10 (May 15, 2008): 1055-1057. Full Text Link to Item
  - Kipp, AM, Stout, JE, Hamilton, CD, and Van Rie, A. "Extrapulmonary tuberculosis, human immunodeficiency virus, and foreign birth in North Carolina, 1993 - 2006. (Published online)" BMC Public Health 8 (April 4, 2008): 107-. Full Text Open Access Copy Link to Item
  - Gadkowski, LB, and Stout, JE. "Cavitary pulmonary disease." Clinical Microbiology Reviews 21, no. 2 (April 2008): 305-333. (Review) Full Text
  - West, EL, Gadkowski, LB, Ostbye, T, Piedrahita, C, and Stout, JE. "Tuberculosis knowledge, attitudes, and beliefs among North Carolinians at increased risk of infection." N C Med J 69, no. 1 (January 2008): 14-20. Link to Item
  - Dukes Hamilton, C, Sterling, TR, Blumberg, HM, Leonard, M, McAuley, J, Schlossberg, D, Stout, J, and Huitt, G. "Extensively drug-resistant tuberculosis: are we learning from history or repeating it?." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 45, no. 3 (August 2007): 338-342. Full Text
  - Tabatabaei, N, Stout, J, Goldschmidt-Clermont, P, and Murdoch, D. "Central nervous system infection and cutaneous lymphadenitis due to Mycobacterium kansasii in an immunocompetent patient." Infection 35, no. 4 (June 2007): 291-294. (Letter, Review) Full Text Link to Item
  - Beth Gadkowski, L, and Stout, JE. "Pharmacokinetics of rifampicin." Clin Infect Dis 44, no. 4 (February 15, 2007): 618-619. (Letter) Full Text Link to Item
  - Stout, JE. "Evaluation and management of patients with pulmonary nontuberculous mycobacterial infections." Expert Rev Anti Infect Ther 4, no. 6 (December 2006): 981-993. (Review) Full Text Link to Item
  - Stout, JE, Ostbye, T, Walter, EB, and Hamilton, CD. "Tuberculosis knowledge and attitudes among physicians who treat young children in North Carolina, USA." Int J Tuberc Lung Dis 10, no. 7 (July 2006): 783-788. Link to Item
  - Stout, JE, Saharia, KK, Nageswaran, S, Ahmed, A, and Hamilton, CD. "Racial and ethnic disparities in pediatric tuberculosis in North Carolina." Arch Pediatr Adolesc Med 160, no. 6 (June 2006): 631-637. Full Text Link to Item
  - Gadkowski, LB, and Stout, JE. "Current challenges in diagnosing and treating nontuberculous mycobacterial pulmonary disease." Infections in Medicine 23, no. 9 (2006): 425-433.
  - Hickey, AJ, Lu, D, Ashley, ED, and Stout, J. "Inhaled azithromycin therapy." Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine 19, no. 1 (January 2006): 54-60. Full Text
  - Frothingham, R, Stout, JE, and Hamilton, CD. "Current issues in global tuberculosis control." International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases 9, no. 6 (November 2005): 297-311. (Review) Full Text
  - McDonald, JR, Friedman, ND, Stout, JE, Sexton, DJ, and Kaye, KS. "Risk factors for ineffective therapy in patients with bloodstream infection." Arch Intern Med 165, no. 3 (February 14, 2005): 308-313. Full Text Link to Item
  - Khuntia, D, and Mehta, M. "Motexafin gadolinium: a clinical review of a novel radioenhancer for brain tumors." Expert review of anticancer therapy 4, no. 6 (December 2004): 981-989. (Review) Full Text
  - Stout, JE, Engemann, JJ, and Hamilton, CD. "Tuberculosis transmission from a patient with skin lesions and a negative sputum smear." N Engl J Med 350, no. 24 (June 10, 2004): 2527-2528. (Letter) Full Text Link to Item
  - Stout, JE. "Safety of rifampin and pyrazinamide for the treatment of latent tuberculosis infection." Expert Opinion on Drug Safety 3, no. 3 (May 2004): 187-198. (Review) Full Text
  - Anderson, DJ, Murdoch, DR, Sexton, DJ, Reller, LB, Stout, JE, Cabell, CH, and Corey, GR. "Risk factors for infective endocarditis in patients with enterococcal bacteremia: a case-control study." Infection 32, no. 2 (April 2004): 72-77. Full Text Link to Item
  - Stout, JE, Engemann, JJ, Cheng, AC, Fortenberry, ER, and Hamilton, CD. "Safety of 2 months of rifampin and pyrazinamide for treatment of latent tuberculosis." American Journal of Respiratory and Critical Care Medicine 167, no. 6 (March 2003): 824-827. Full Text
  - Berchuck, A, Alvarez, AA, and Stout, JE. "Abdominal pain and bloating in two 20-something patients." Contemporary Ob/Gyn 48, no. 1 (2003): 51-58.
  - Friedman, ND, Kaye, KS, Stout, JE, McGarry, SA, Trivette, SL, Briggs, JP, Lamm, W, Clark, C, MacFarquhar, J, Walton, AL, Reller, LB, and Sexton, DJ. "Health care--associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections." Annals of Internal Medicine 137, no. 10 (November 2002): 791-797. Full Text
  - Stout, JE, Lai, JC, Giner, J, and Hamilton, CD. "Reactivation of retinal toxoplasmosis despite evidence of immune response to highly active antiretroviral therapy." Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America 35, no. 4 (August 2002): e37-e39. Full Text
  - Stout, JE, Ratard, R, Southwick, KL, and Hamilton, CD. "Epidemiology of human immunodeficiency virus testing among patients with tuberculosis in North Carolina." Southern Medical Journal 95, no. 2 (February 2002): 231-238.
  - Alexander, BD, Stout, JE, Reller, LB, and Hamilton, CD. "Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria." Infect Control Hosp Epidemiol 22, no. 11 (November 2001): 715-717. Full Text Link to Item
  - McDonald, JR, Stout, JE, Sharps, SK, and Hamilton, CD. "Impact of highly active antiretroviral therapy on survival of patients with disseminated Mycobacterium avium in complex disease associated with late-stage human immunodeficiency virus infection." CLINICAL INFECTIOUS DISEASES 33, no. 7 (October 1, 2001): 1219-1219. Link to Item
  - Stout, JE, Woods, CW, Alvarez, AA, Berchuck, A, and Dukes Hamilton, C. "Mycobacterium bovis peritonitis mimicking ovarian cancer in a young woman." Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America 33, no. 4 (August 2001): E14-E16. Full Text
  - Stout, JE, McDonald, JR, Engemann, JJ, Alexander, BD, and Hamilton, CD. "Conditions associated with pulmonary non-tuberculous mycobacteria (NTM) in a tertiary care hospital in the Southeastern US." CLINICAL INFECTIOUS DISEASES 31, no. 1 (July 2000): 311-311. Link to Item
  - Alexander, BD, Stout, JE, Reller, LB, and Hamilton, CD. "Hospital management of patients suspected of pulmonary TB in a high incidence area for MOTT." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159, no. 3 (March 1999): A304-A304. Link to Item
Teaching & Mentoring
Advising & Mentoring
- Kapil Saharia (Duke medical student): Comentored with Carol Hamilton for MPH thesis, “Racial and ethnic disparities characterize pediatric tuberculosis in North Carolina.” Obtained MPH summer 2003. Currently Assistant Professor, Division of Infectious Diseases, University of Maryland
  
  Lee Ann Morehead (physician assistant student, Wake Forest University): Mentored for Masters’ Research project: “Knowledge of, attitudes to and beliefs about tuberculosis among North Carolinians at increased risk of infection: results from a series of focus groups.” Project presented successfully 5/2005. Currently physician assistant, Department of Dermatology, Duke University Medical Center.
  
  L. Beth Gadkowski (Duke resident/infectious diseases fellow): Comentored with Carol Hamilton. Resident project: “Tuberculosis knowledge, attitudes and beliefs among North Carolinians at increased risk of infection: results from a series of focus groups.” Fellow project examined healthcare utilization and outcomes among persons with TB/HIV in North Carolina. Currently Assistant Professor, Division of Infectious Diseases, Eastern Virginia Medical School.
  
  Aaron Kipp (UNC-Chapel Hill PhD student, epidemiology): Comentored with Carol Hamilton, Annalies VanRie, “Epidemiology of extrapulmonary tuberculosis in North Carolina.” Masters’ thesis, UNC School of Public Health. Currently Assistant Professor, School of Public Health, Vanderbilt University.
  
  Lisa Nguyen (Duke medical student): Comentored with Carol Hamilton for MPH thesis, “Predictors of Mortality among Tuberculosis Patients in North Carolina.” Successfully presented thesis summer 2005. Also precepted in clinic 7/04-7/05. Currently in practice, Mayo Clinic, Scottsdale, AZ.
  
  Christina Fiske (Taulien) (Duke resident): Comentored with Carol Hamilton for resident research project, “A Retrospective Study of the Association Between Alcoholism and Tuberculosis in the United States and North Carolina Between 1994 and 2003.” Currently Assistant Professor of Medicine, Division of Infectious Diseases, Vanderbilt University.
  
  Neela Goswami (Duke resident/infectious diseases fellow): Mentoring for resident research project, Location-based Screenings with Serum Quantiferon-TB Gold In-Tube Compared to Clinic-based Screenings in Detection of Latent TB. Awarded Barton F. Haynes resident research award for this project and Center for AIDS Research small grant award. Currently at the Centers for Disease Control and Prevention, Field Services Branch, Division of Tuberculosis Elimination, Atlanta, GA.
  
  David P. Holland (Duke infectious diseases fellow): Comentored with Carol Hamilton and Gillian Sanders for fellowship research projects, primarily focusing on the use of decision analysis to assist with formulating policies and guidelines for treatment of latent tuberculosis infection and exposures to multi-drug resistant tuberculosis. Also primary mentor for Master’s thesis project, Duke MHS program. Currently Assistant Professor of Medicine, Division of Infectious Diseases, Emory University, Atlanta, GA.
  
  Anna K. Person (Duke infectious diseases fellow): Research mentor for fellowship project: Text messaging to Enhance Testing and Treatment for Tuberculosis, HIV, and Syphilis (TEXTT THIS). Currently Assistant Professor of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN.
  
  Laura Guderian (UNC-Chapel Hill infectious diseases fellow/preventive medicine resident). Comentoring with Arlene Sena and William Miller, project: Association between rural location and tuberculosis presentation in North Carolina. Currently in private practice at One Medical Group, New York, NY.
  
  Kia Armstrong (CDC Public Health Prevention Specialist). Comentored with Maureen O’Rourke, project: Association between staff experience and effective tuberculosis contact tracing, North Carolina, 2008–2009. Currently working for Centers for Disease Control and Prevention, Division of Tuberculosis Elimination.
  
  Paul Park (Duke medical resident). Clinical mentor, subspecialty clinic (TB clinic), and research mentor for resident project: Costs of nontuberculous mycobacterial infections to a public health tuberculosis clinic. Awarded a Duke Resident Research Award to conduct this project. Currently employed by Partners in Health.
  
  Brianna Norton (Duke infectious diseases fellow). Comentored with Susanna Naggie, “Acceptability of Community-Based Hepatitis C Testing in Wake County, North Carolina.” Currently Assistant Professor, Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY.
  
  Charles McCormick (Duke medicine-psychiatry resident). Clinical mentor, subspecialty clinic (TB clinic) and research mentor for resident project: Tobacco use, tuberculosis infection, and comorbidities among tuberculosis clinic attendees in Wake County, North Carolina. Currently in private practice in Raleigh, NC.
  
  Michael Woodworth (Duke medicine resident). 2013-2015. Research mentor for resident project: Nocardia at Duke University Medical Center 1996-2013. Awarded a Duke Resident Research Award to conduct this project. Currently infectious diseases fellow, Emory University, Atlanta, GA.
  
  Matthew Johnson (Duke infectious diseases fellow). “Xpert MTB/RIF testing among HIV-positive patients in Zambia”, mentor during research years of fellowship, 7/2014-6/2016. Currently at Merck.
  
  Dana Clifton (Duke medicine/pediatrics resident). Research mentor for resident project: HIV testing among pneumonia patients at Duke. Awarded a Duke Resident Research Award to conduct this project. Currently hospitalist, Duke University Medical Center.
  
  Lauren Collins (Duke medicine resident). Research mentor for resident project: Long term outcomes of patients with AIDS and disseminated Mycobacterium avium intracellulare. Awarded a Duke Resident Research Award to conduct this project. Currently infectious diseases fellow, Emory University, Atlanta, GA.

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Education, Training, & Certifications

Duke Appointment History

Leadership & Clinical Positions at Duke

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Journal Articles

Advising & Mentoring