Sylvia Fernandes de Castro Costa

Chapter · January 1, 2019 In organ transplant recipients, impaired inflammatory responses suppress the clinical and radiologic findings of infection. The possible etiologies of infection are diverse, ranging from common bacterial and viral pathogens that affect the entire community ... Full text Cite

Adenovirus Type 21 Outbreak Among Lung Transplant Patients at a Large Tertiary Care Hospital.

Journal Article Open Forum Infect Dis · August 2018 Here we summarize an April 2016, 7-patient cluster of human adenovirus (HAdV) infections in a cardiothoracic surgery intensive care unit. We show that the patients were infected with a single HAdV21b type. Rapid HAdV typing diagnostics and effective antivi ... Full text Link to item Cite

Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing.

Journal Article Open Forum Infect Dis · September 2016 We report the case of a 60-year-old man with septic shock due to Capnocytophaga canimorsus that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay. This technology shows great promise in identifying fastidious pathogens, and ... Full text Open Access Link to item Cite

Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction.

Journal Article Clin Transplant · 2013 BK polyomavirus (BKV) infection continues to be a significant source of allograft dysfunction in kidney transplant recipients. The optimal screening method to detect BKV remains undetermined. In this retrospective analysis of 347 consecutive kidney transpl ... Full text Link to item Cite

The clinical and prognostic importance of positive blood cultures in adults.

Journal Article Am J Med · September 2010 BACKGROUND: Bloodstream infections are a major cause of morbidity and mortality in adults. Bloodstream infections should be reassessed periodically because of increased antibiotic resistance, more patients receiving immunomodulatory therapy, improved antir ... Full text Link to item Cite

Non-Aspergillus fungal pneumonia in transplant recipients.

Journal Article Clin Chest Med · December 2005 Although species of Aspergillus and Candida account for most deeply invasive and life-threatening fungal infections, the past decades have seen a rise in the immunocompromised population. With this increase, additional fungi have emerged as important agent ... Full text Link to item Cite

Role of vasoactive mediators in the pathogenesis of Chagas' disease.

Journal Article Front Biosci · May 1, 2003 This review focuses on the vascular pathogenesis of Chagas' disease, the cardiomyopathy caused by infection with the parasitic protozoa Trypanosoma cruzi. Recent studies strongly suggests that T. cruzi infection is linked to functional changes in the activ ... Full text Link to item Cite

Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic Mycobacterium from moray eels that is related to Mycobacterium triplex.

Journal Article J Clin Microbiol · May 2003 The characterization of a novel Mycobacterium sp. isolated from granulomatous skin lesions of moray eels is reported. Analysis of the hsp65 gene, small-subunit rRNA gene, rRNA spacer region, and phenotypic characteristics demonstrate that this organism is ... Full text Link to item Cite

Role of vasoactive mediators in the pathogenesis of Chagas' disease

Journal Article Frontiers in Bioscience · January 1, 2003 This review focuses on the vascular pathogenesis of Chagas' disease, the cardiomyopathy caused by infection with the parasitic protozoa Trypanosoma cruzi. Recent studies strongly suggests that T. cruzi infection is linked to functional changes in the activ ... Cite

Granulomatous skin lesions in moray eels caused by a novel Mycobacterium species related to Mycobacterium triplex.

Journal Article Infect Immun · July 2001 An outbreak of granulomatous dermatitis was investigated in a captive population of moray eels. The affected eels had florid skin nodules concentrated around the head and trunk. Histopathological examination revealed extensive granulomatous inflammation wi ... Full text Link to item Cite

Microsporidian methionine aminopeptidase type 2.

Journal Article J Eukaryot Microbiol · 2001 Full text Link to item Cite

Drug treatment of microsporidiosis.

Journal Article Drug Resist Updat · December 2000 Microsporidia are ubiquitous organisms that are emerging pathogens in humans. These are most likely zoonotic and/or waterborne infections. In the immunosuppressed host, such as those treated with immunosuppressive drugs or infected with human immunodeficie ... Full text Link to item Cite

Diagnosis of Capnocytophaga canimorsus sepsis by whole genome next-generation sequencing.

Journal Article Open Forum Infectious Diseases Cite