Scholars@Duke
Edward Ferguson Hendershot

Edward Ferguson Hendershot

Associate Professor of Medicine
Medicine, Infectious Diseases
ted.hendershot@duke.edu
Duke Box 102359, Durham, NC 27710
Rm 163,Hanes House, Trent Drive, Durham, NC 27710

Selected Publications

Clinic of Hope: bridging infectious disease and orthopaedic surgery in prosthetic joint infection management.

Journal Article BMJ Open Qual · August 21, 2024 Prosthetic joint infections (PJIs) following total joint arthroplasty are a significant and costly complication. To address fragmented care typically seen with separate management, we established a combined infectious disease and orthopaedic surgery clinic ... Full text Link to item Cite

Mycoplasma hominis: A Case of Peritonitis and Hyperammonemia Syndrome in a Healthy Postpartum Woman

Journal Article Annals of Internal Medicine Clinical Cases · April 1, 2024 An 18-year-old woman with a recent uncomplicated spontaneous vaginal delivery presented with altered mental status and new ascites. She had elevated ammonia and blood urea nitrogen levels with normal hepatic enzymes. Peritoneal cultures eventually grew Myc ... Full text Cite

D-Dimer, Erythrocyte Sedimentation Rate, and C-Reactive Protein Sensitivities for Periprosthetic Joint Infection Diagnosis.

Journal Article J Arthroplasty · May 2023 BACKGROUND: There is contradicting evidence on the diagnostic value of inflammatory biomarkers for periprosthetic joint infection (PJI). We sought to quantify the sensitivity of D-dimer for acute and chronic PJI diagnosis and evaluate D-dimer lab values in ... Full text Link to item Cite

Team Approach: Metal Hypersensitivity in Total Joint Arthroplasty.

Journal Article JBJS Rev · January 1, 2023 »: As total joint arthroplasty volume continues to grow nationwide, more uncommon complications such as metal implant hypersensitivity are reported with greater frequency in the literature. »: Metal hypersensitivity is a challenging diagnosis given the pot ... Full text Link to item Cite

Prosthetic Knee Infection With Coagulase-Negative Staphylococcus: A Harbinger of Poor Outcomes.

Journal Article J Arthroplasty · June 2022 BACKGROUND: Coagulase-negative staphylococci (CoNS) are biofilm-producing pathogens whose role in periprosthetic joint infection (PJI) is increasing. There is little data on the prognosis and treatment considerations in the setting of PJI. We sought to eva ... Full text Link to item Cite

Reply to Werth et al

Journal Article Clinical Infectious Diseases · January 1, 2021 Full text Cite

Extirpative Cultures Reveal Infectious Pubic Bone Osteomyelitis in Prostate Cancer Survivors With Urinary-Pubic Symphysis Fistulae (UPF).

Journal Article Urology · August 2020 OBJECTIVE: To examine the infectious features of patients with urinary pubic symphysis fistula (UPF) and their association with osteomyelitis. METHODS: We conducted a review of our quality improvement database for 36 patients with UPF undergoing bone resec ... Full text Open Access Link to item Cite

Musculoskeletal Infection in Orthopaedic Trauma: Assessment of the 2018 International Consensus Meeting on Musculoskeletal Infection.

Journal Article J Bone Joint Surg Am · May 20, 2020 Fracture-related infections (FRIs) are among the most common complications following fracture fixation, and they have a huge economic and functional impact on patients. Because consensus guidelines with respect to prevention, diagnosis, and treatment of th ... Full text Link to item Cite

2018 international consensus meeting on musculoskeletal infection: Summary from the biofilm workgroup and consensus on biofilm related musculoskeletal infections.

Journal Article J Orthop Res · May 2019 Biofilm-associated implant-related bone and joint infections are clinically important due to the extensive morbidity, cost of care and socioeconomic burden that they cause. Research in the field of biofilms has expanded in the past two decades, however, th ... Full text Link to item Cite

Reply to Dr Fierer.

Journal Article Clin Infect Dis · April 1, 2016 Full text Link to item Cite

2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults.

Journal Article Clin Infect Dis · September 15, 2015 These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO). They include evidence and opinion ... Full text Link to item Cite

Executive Summary: 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults.

Journal Article Clin Infect Dis · September 15, 2015 These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, radiologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO). They include evidence and opinion ... Full text Link to item Cite

Pubic symphysis osteomyelitis in the prostate cancer survivor: clinical presentation, evaluation, and management.

Journal Article Urology · March 2015 OBJECTIVE: To describe pelvic bone osteomyelitis in the prostate cancer survivor, to report on clinical presentation and treatment, and to suggest an algorithmic approach to managing this syndrome complex. MATERIALS AND METHODS: A retrospective chart revie ... Full text Link to item Cite

An Infection Control Program for a 2009 influenza A H1N1 outbreak in a university-based summer camp.

Journal Article J Am Coll Health · 2011 OBJECTIVES: Describe two 2009-H1N1 influenza outbreaks in university-based summer camps and the implementation of an infection control program. PARTICIPANTS: 7,906 campers across 73 residential camps from May 21-August 2, 2009. METHODS: Influenza-like-illn ... Full text Link to item Cite

Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population.

Journal Article J Clin Virol · March 2010 BACKGROUND: Little is known about the clinical presentation and course of novel H1N1 influenza in summer camps. OBJECTIVES: To describe the clinical course and evaluate the effect of influenza treatment in a summer camp population. STUDY DESIGN: Two large ... Full text Link to item Cite

Scrub typhus and rickettsial diseases in international travelers: a review.

Journal Article Curr Infect Dis Rep · January 2009 Physicians caring for febrile returned travelers face the difficult task of recognizing the typical and atypical features of more than 16 known rickettsial diseases and separating these diseases from potentially serious nonrickettsial diseases. Currently a ... Full text Link to item Cite

Persistence of the same Candida albicans strain despite fluconazole therapy. Documentation by pulsed-field gel electrophoresis.

Journal Article Diagn Microbiol Infect Dis · August 1992 Candida albicans and other Candida species have emerged as major nosocomial pathogens associated with a high mortality. Therapeutic options for fungal infections are limited. Amphotericin B has been the mainstay of treatment for serious systemic candidal i ... Full text Link to item Cite