Overview
Theresa Coles, Ph.D., is a health outcomes methodologist with a focus on measuring and evaluating patient-reported outcomes (PROs) and other clinical outcomes assessments (COAs), integrating PRO measures for screening of symptoms in clinical care (PROMs for screening), and improving interpretation of patient-centered outcome scores for use in healthcare delivery and clinical research settings to inform decision making. I am excited by opportunities to use COA scores to support actionable decision-making in clinical care.
My research program is comprised of 2 pillars:
- Enhance the assessment of function (e.g., physical function, cognitive function) to inform decision-making
- Design patient-reported screening questionnaires to improve patient-centered care by measuring what matters
Applications of my work are in a range of conditions such as cancer, heart failure, orthopedics, hearing healthcare, sinusitis, Eustachian tube dysfunction, migraine, autoimmune conditions, and hematologic conditions.
Current Appointments & Affiliations
Associate Professor in Population Health Sciences
·
2024 - Present
Population Health Sciences,
Basic Science Departments
Recent Publications
Transitions in Psychological Distress Phenotypes and Patient-Reported Outcomes Among Patients Undergoing Total Joint Arthroplasty.
Journal Article ACR Open Rheumatol · January 2026 Psychological distress is common in individuals undergoing total joint arthroplasty (TJA). Understanding psychological phenotypes and their transitions from before to after surgery can inform risk stratification and targeted care. This study aimed to chara ... Full text Link to item CiteDevelopment of the Sinus Headache Screener to identify patients with non-rhinogenic facial pain compared with chronic rhinosinusitis in rhinology clinics.
Journal Article J Patient Rep Outcomes · November 6, 2025 PURPOSE: To develop a patient-reported screening tool, the Sinus Headache Screener (SHS), to differentiate non-rhinogenic facial pain (NRFP) from chronic rhinosinusitis (CRS) using qualitative research methods. METHODS: We conducted semi-structured intervi ... Full text Link to item CiteUtility of Existing Patient-Reported Outcome Measures for Identifying Non-Rhinogenic Facial Pain.
Journal Article Laryngoscope · August 2025 OBJECTIVE: Facial pain/pressure is often non-rhinogenic and migraine-related in etiology. However, this is frequently misdiagnosed as sinusitis, leading to inappropriate antibiotic utilization and unnecessary procedures. We assessed the utility of the 3-It ... Full text Link to item CiteRecent Grants
FDA - BAA Clinical Evidence on the impact of osseointegrated limb prostheses
ResearchCo Investigator · Awarded by Food and Drug Administration · 2023 - 2026A Clinical Trial Readiness Study of Patient Reported Outcome Measures in Thrombotic Thrombocytopenic Purpura (TTP)
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2026Optimizing the Management and Outcomes for Cancer Survivors Transitioning to Follow-up Care
ResearchCo Investigator · Awarded by National Cancer Institute · 2020 - 2026View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2017
Ph.D.
External Links
Center for Health Measurement Department of Population Health Sciences Evaluating physical functioning using patient-reported outcome measures: how does the question form and recall period influence patients’ interpretation? Enabling Patient-Reported Outcome Measures (PROMs) in Clinical Trials, Exemplified by Cardiovascular Trials Recall of patient-reported symptoms and function in episodic disease/conditions, specifically temporomandibular disorders