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Timothy Robert Koves

Associate Professor in Medicine
Medicine, Geriatrics and Palliative Care
Duke Box 104775, Durham, NC 27704
300 North Duke Street, 50-202 / Carmichael Bldg, Durham, NC 27701

Selected Grants


Mechanisms of lipid-induced bioenergetic stress in muscle

ResearchCo Investigator · Awarded by National Institutes of Health · 2010 - 2028

Novel roles of PDK4 in regulating mitochondrial protein phosphorylation, carbon flux and metabolic resilience

ResearchInvestigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2022 - 2027

Microbial regulation of intestinal lipid metabolism and its physiological consequences

ResearchAssociate Research Professor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2021 - 2025

Probing the Role of Mitochondrial Short-chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchInvestigator · Awarded by University of Pennsylvania · 2021 - 2025

Metabolic inflexibility is related to elevated muscle anaerobic glycolysis

ResearchInvestigator · Awarded by East Carolina University · 2020 - 2025

Ketone Body Metabolism and Integrated Metabolic Homeostasis

ResearchInvestigator · Awarded by University of Minnesota · 2020 - 2024

STIM1 and mitochondrial quality control

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2024

Systemic Inflammation in Microphysiological Models of Muscle and Vascular Disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2022

Pilot Study: Testing of Comprehensive Mitochondrial Profiling Platform in Islet cells

ResearchCo-Principal Investigator · Awarded by Eli Lilly and Company · 2020 - 2022

Probing the Role of Mitochondrial Short-Chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchProject Manager · Awarded by University of Pennsylvania · 2017 - 2021

Microbial regulation of host nutrient metabolism

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 2013 - 2020

Circulatory system and integrated muscle tissue for drug and tissue toxicity

ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2018

Probing the role of Mitochondrial Short-Chain Carbon Homeostasis in the Hypertrophied and Failing Heart

ResearchCo Investigator · Awarded by Sanford-Burnham Medical Research Institute · 2017 - 2017

Mechanisms linking the adipogenic phenotype of aging muscle to insulin resistance

ResearchInvestigator · Awarded by National Institutes of Health · 2006 - 2012

Molecular Genetics of Muscle Specialization

ResearchCo Investigator · Awarded by National Institutes of Health · 2001 - 2009