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Timothy James Amrhein

Associate Professor of Radiology
Radiology, Neuroradiology
Box 3808 Med Ctr, Durham, NC 27710
Dept of Radiology, Durham, NC 27710

Research Interests


Dr. Amrhein leads a team of spine researchers focusing on Spontaneous Intracranial Hypotension and CT guided pain interventions. He has been first author or a co-author on innumerable peer-reviewed publications and has written multiple book chapters. His work has been published in JAMA Neurology, PLOS Med, Nature: NPJ Digital Medicine, Radiology, American Journal of Radiology, Headache, and the American Journal of Neuroradiology with features in the popular press ranging from national outlets such as the New York Times and Reuters to the local press (WRAL). Dr. Amrhein’s research has been supported through multiple grants including several highly competitive national foundation awards: the RSNA Research Scholar Grant, ASNR Comparative Effectiveness Award, Spine Intervention Society Research Grant, the American Heart Association Bugher Fellowship, and a Spinal CSF Leak Foundation Grant.

Selected Grants


Population-level Pulmonary Embolism Outcome Prediction with Imaging and Clinical Data: A Multi-Center Study

ResearchPrincipal Investigator · Awarded by Stanford University · 2021 - 2025

A flexible needle for targeted delivery of therapeutics in spatially constrained anatomy

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2021 - 2023

Applied Deep Learning in Pulmonary Embolism Outcome Prediction Using Imaging and Clinical Data: A Multicenter Study

ResearchPrincipal Investigator · Awarded by Stanford University · 2018 - 2022

Deep Learning for Pulmonary Embolism Imaging Decision Support: A Multi-institutional Collaboration

ResearchPrincipal Investigator · Awarded by Stanford University · 2018 - 2022

Duke-Stanford Multicenter Investigation Predicting Imaging Outcomes of Pulmonary Embolism CT

ResearchPrincipal Investigator · Awarded by Stanford University · 2017 - 2022

External Relationships


  • Siemens Medical Solutions/Siemens Healthineers
  • Spinal CSF Leak Foundation

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.