Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Nephrology, Medicine, University of Wisconsin - Madison 1989 - 1990
  • Resident, Medicine, University of Wisconsin - Madison 1987 - 1989
  • M.B.B.S., University of Melbourne (Australia) 1981
• 

  Duke Appointment History

  • Professor of Medicine, Medicine, Nephrology, Medicine 2010 - 2020
  • Instructor, Temporary in the Department of Medicine, Medicine, Nephrology, Medicine 2009
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Hammond, Timothy G., Patricia L. Allen, and Holly H. Birdsall. “Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses.” Int J Mol Sci 19, no. 12 (December 18, 2018). https://doi.org/10.3390/ijms19124106.
       Full Text  Link to Item
    • Hammond, T. G., P. L. Allen, and H. H. Birdsall. “Gene Pathways Analysis of the Effects of Suspension Culture on Primary Human Renal Proximal Tubular Cells.” Microgravity Science and Technology 30, no. 6 (December 1, 2018): 951–63. https://doi.org/10.1007/s12217-018-9658-x.
       Full Text
    • Hammond, Timothy G., Patricia L. Allen, Margaret A. Gunter, Jennifer Chiang, Guri Giaever, Corey Nislow, and Holly H. Birdsall. “Physical Forces Modulate Oxidative Status and Stress Defense Meditated Metabolic Adaptation of Yeast Colonies: Spaceflight and Microgravity Simulations.” Microgravity Sci Technol 30, no. 3 (2018): 195–208. https://doi.org/10.1007/s12217-017-9588-z.
       Full Text  Link to Item
    • Hammond, Timothy G., and Holly H. Birdsall. “Hepatocyte CYP2B6 Can Be Expressed in Cell Culture Systems by Exerting Physiological Levels of Shear: Implications for ADME Testing.” J Toxicol 2017 (2017): 1907952. https://doi.org/10.1155/2017/1907952.
       Full Text  Link to Item
    • Hammond, Timothy, Patricia Allen, and Holly Birdsall. “Is There a Space-Based Technology Solution to Problems with Preclinical Drug Toxicity Testing?” Pharm Res 33, no. 7 (July 2016): 1545–51. https://doi.org/10.1007/s11095-016-1942-0.
       Full Text  Link to Item
    • Nislow, Corey, Anna Y. Lee, Patricia L. Allen, Guri Giaever, Andrew Smith, Marinella Gebbia, Louis S. Stodieck, Jeffrey S. Hammond, Holly H. Birdsall, and Timothy G. Hammond. “Genes required for survival in microgravity revealed by genome-wide yeast deletion collections cultured during spaceflight.” Biomed Res Int 2015 (2015): 976458. https://doi.org/10.1155/2015/976458.
       Full Text  Link to Item
    • Hammond, T. G., H. H. Birdsall, J. S. Hammond, and P. L. Allen. “Optimizing host-pathogen in-flight assays for c. Elegans and methicillin-resistant staphylococcus aureus.” European Space Agency, (Special Publication) Esa Sp 706 SP (December 1, 2013).
    • Hammond, Timothy G., Louis Stodieck, Holly H. Birdsall, Jeanne L. Becker, Paul Koenig, Jeffrey S. Hammond, Margaret A. Gunter, and Patricia L. Allen. “Effects of microgravity on the virulence of Listeria monocytogenes, Enterococcus faecalis, Candida albicans, and methicillin-resistant Staphylococcus aureus.” Astrobiology 13, no. 11 (November 2013): 1081–90. https://doi.org/10.1089/ast.2013.0986.
       Full Text  Link to Item
    • Hammond, T. G., L. Stodieck, H. H. Birdsall, J. Becker, P. Koenig, J. S. Hammond, M. A. Gunter, and P. L. Allen. “Effects of Microgravity on the Virulence of Salmonella Toward Caenorhabditis elegans.” New Space 1, no. 3 (January 1, 2013): 123–31. https://doi.org/10.1089/space.2013.0011.
       Full Text
    • Hammond, T., and P. Allen. “The Bonn criteria: Minimal experimental parameter reporting for clinostat and random positioning machine experiments with cells and tissues.” Microgravity Science and Technology 23, no. 2 (February 1, 2011): 271–75. https://doi.org/10.1007/s12217-010-9226-5.
       Full Text
    • Allen, D. L., E. R. Bandstra, B. C. Harrison, S. Thorng, L. S. Stodieck, P. J. Kostenuik, S. Morony, et al. “Erratum: Effects of spaceflight on murine skeletal muscle gene expression (Journal of Applied Physiology (2009) 106 (582-595) DOI: 10.1152/japplphysiol. 90780.2008).” Journal of Applied Physiology 110, no. 1 (January 1, 2011): 299. https://doi.org/10.1152/japplphysiol.zdg-9426-corr.2010.
       Full Text
    • Allen, David L., Eric R. Bandstra, Brooke C. Harrison, Seiha Thorng, Louis S. Stodieck, Paul J. Kostenuik, Sean Morony, et al. “Effects of spaceflight on murine skeletal muscle gene expression.” J Appl Physiol (1985) 106, no. 2 (February 2009): 582–95. https://doi.org/10.1152/japplphysiol.90780.2008.
       Full Text  Link to Item
    • Coleman, Chasity B., Patricia L. Allen, Mark Rupert, Carla Goulart, Alexander Hoehn, Louis S. Stodieck, and Timothy G. Hammond. “Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight.” Astrobiology 8, no. 6 (December 2008): 1071–78. https://doi.org/10.1089/ast.2007.0211.
       Full Text  Link to Item
    • Coleman, Chasity B., Patricia L. Allen, James M. Valles, and Timothy G. Hammond. “Transcriptional regulation of changes in growth, cell cycle, and gene expression of Saccharomyces cerevisiae due to changes in buoyancy.” Biotechnol Bioeng 100, no. 2 (June 1, 2008): 334–43. https://doi.org/10.1002/bit.21748.
       Full Text  Link to Item
    • Pohorille, A., T. Hammond, K. Schweighofer, P. Allen, L. Stodieck, T. Bateman, N. Szewczyk, and S. Chang. “Spaceflight-induced gene expression changes in the mouse liver and kidney.” International Astronautical Federation  58th International Astronautical Congress 2007 1 (December 1, 2007): 112–13.
    • Coleman, Chasity B., Romer A. Gonzalez-Villalobos, Patricia L. Allen, Kelly Johanson, Karine Guevorkian, James M. Valles, and Timothy G. Hammond. “Diamagnetic levitation changes growth, cell cycle, and gene expression of Saccharomyces cerevisiae.” Biotechnol Bioeng 98, no. 4 (November 1, 2007): 854–63. https://doi.org/10.1002/bit.21526.
       Full Text  Link to Item
    • Wilson, J. W., C. M. Ott, K. Höner zu Bentrup, R. Ramamurthy, L. Quick, S. Porwollik, P. Cheng, et al. “Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq.” Proc Natl Acad Sci U S A 104, no. 41 (October 9, 2007): 16299–304. https://doi.org/10.1073/pnas.0707155104.
       Full Text  Link to Item
    • Caplanusi, Adrian, Andrew J. Fuller, Romer A. Gonzalez-Villalobos, Timothy G. Hammond, and L. G. Navar. “Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line.” Am J Physiol Renal Physiol 293, no. 2 (August 2007): F533–40. https://doi.org/10.1152/ajprenal.00030.2007.
       Full Text  Link to Item
    • Morré, D James, and Timothy Hammond. “Isolation of renal brush borders.” Curr Protoc Cell Biol Chapter 3 (March 2007): Unit-3.26. https://doi.org/10.1002/0471143030.cb0326s34.
       Full Text  Link to Item
    • Johanson, K., P. L. Allen, R. A. Gonzalez-Villalobos, J. Nesbit, C. A. Nickerson, K. Höner zu Bentrup, J. W. Wilson, et al. “Haploid deletion strains of Saccharomyces cerevisiae that determine survival during space flight.” Acta Astronautica 60, no. 4-7 SPEC. ISS. (February 1, 2007): 460–71. https://doi.org/10.1016/j.actaastro.2006.09.011.
       Full Text
    • Gonzalez-Villalobos, Romer, R Bryan Klassen, Patricia L. Allen, Kelly Johanson, Chasity B. Baker, Hiroyuki Kobori, L. G. Navar, and Timothy G. Hammond. “Megalin binds and internalizes angiotensin-(1-7).” Am J Physiol Renal Physiol 290, no. 5 (May 2006): F1270–75. https://doi.org/10.1152/ajprenal.00164.2005.
       Full Text  Link to Item
    • Johanson, Kelly, Patricia L. Allen, Romer A. Gonzalez-Villalobos, Chasity B. Baker, Riccardo D’Elia, and Timothy G. Hammond. “Gene expression and survival changes in Saccharomyces cerevisiae during suspension culture.” Biotechnol Bioeng 93, no. 6 (April 20, 2006): 1050–59. https://doi.org/10.1002/bit.20810.
       Full Text  Link to Item
    • D’Elia, Riccardo, Patricia L. Allen, Kelly Johanson, Cheryl A. Nickerson, and Timothy G. Hammond. “Homozygous diploid deletion strains of Saccharomyces cerevisiae that determine lag phase and dehydration tolerance.” Appl Microbiol Biotechnol 67, no. 6 (June 2005): 816–26. https://doi.org/10.1007/s00253-004-1793-1.
       Full Text  Link to Item
    • Shivakumar, Bangalore R., Zoufei Wang, Timothy G. Hammond, and Raymond C. Harris. “EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor.” Cell Biochem Funct 23, no. 3 (May 2005): 195–204. https://doi.org/10.1002/cbf.1176.
       Full Text  Link to Item
    • Gonzalez-Villalobos, Romer, R Bryan Klassen, Patricia L. Allen, L. G. Navar, and Timothy G. Hammond. “Megalin binds and internalizes angiotensin II.” Am J Physiol Renal Physiol 288, no. 2 (February 2005): F420–27. https://doi.org/10.1152/ajprenal.00243.2004.
       Full Text  Link to Item
    • Klassen, R Bryan S., Patricia L. Allen, Vecihi Batuman, Kimberly Crenshaw, and Timothy G. Hammond. “Light chains are a ligand for megalin.” J Appl Physiol (1985) 98, no. 1 (January 2005): 257–63. https://doi.org/10.1152/japplphysiol.01090.2003.
       Full Text  Link to Item
    • Klassen, R Bryan, Kimberly Crenshaw, Renata Kozyraki, Pierre J. Verroust, Laura Tio, Sílvia Atrian, Patricia L. Allen, and Timothy G. Hammond. “Megalin mediates renal uptake of heavy metal metallothionein complexes.” Am J Physiol Renal Physiol 287, no. 3 (September 2004): F393–403. https://doi.org/10.1152/ajprenal.00233.2003.
       Full Text  Link to Item
    • Struckhoff, Amanda P., Robert Bittman, Matthew E. Burow, Sanda Clejan, Steven Elliott, Timothy Hammond, Yan Tang, and Barbara S. Beckman. “Novel ceramide analogs as potential chemotherapeutic agents in breast cancer.” J Pharmacol Exp Ther 309, no. 2 (May 2004): 523–32. https://doi.org/10.1124/jpet.103.062760.
       Full Text  Link to Item
    • Klaus, David M., Michael R. Benoit, Emily S. Nelson, and Timmothy G. Hammond. “Extracellular mass transport considerations for space flight research concerning suspended and adherent in vitro cell cultures.” J Gravit Physiol 11, no. 1 (March 2004): 17–27.
       Link to Item
    • Becker, Bryan N., Hui-fang Cheng, Timothy G. Hammond, and Raymond C. Harris. “The type 1 angiotensin II receptor tail affects receptor targeting, internalization, and membrane fusion properties.” Mol Pharmacol 65, no. 2 (February 2004): 362–69. https://doi.org/10.1124/mol.65.2.362.
       Full Text  Link to Item
    • Gambelli, Federica, Peter Di, Xiaomei Niu, Mitchell Friedman, Timothy Hammond, David W. H. Riches, and Luis A. Ortiz. “Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis.” J Biol Chem 279, no. 3 (January 16, 2004): 2020–29. https://doi.org/10.1074/jbc.M309763200.
       Full Text  Link to Item
    • Nickerson, Cheryl A., C Mark Ott, James W. Wilson, Rajee Ramamurthy, Carly L. LeBlanc, Kerstin Höner zu Bentrup, Timothy Hammond, and Duane L. Pierson. “Low-shear modeled microgravity: a global environmental regulatory signal affecting bacterial gene expression, physiology, and pathogenesis.” J Microbiol Methods 54, no. 1 (July 2003): 1–11. https://doi.org/10.1016/s0167-7012(03)00018-6.
       Full Text  Link to Item
    • Puliyanda, Dechu P., Donald T. Ward, Michelle A. Baum, Timothy G. Hammond, and H William Harris. “Calpain-mediated AQP2 proteolysis in inner medullary collecting duct.” Biochem Biophys Res Commun 303, no. 1 (March 28, 2003): 52–58. https://doi.org/10.1016/s0006-291x(03)00215-8.
       Full Text  Link to Item
    • Braam, Branko, Pat Allen, Ed Benes, Hein A. Koomans, L Gabriel Navar, and Timothy Hammond. “Human proximal tubular cell responses to angiotensin II analyzed using DNA microarray.” Eur J Pharmacol 464, no. 2–3 (March 19, 2003): 87–94. https://doi.org/10.1016/s0014-2999(03)01382-7.
       Full Text  Link to Item
    • Johanson, Kelly, Patricia L. Allen, Fawn Lewis, Luis A. Cubano, Linda E. Hyman, and Timothy G. Hammond. “Saccharomyces cerevisiae gene expression changes during rotating wall vessel suspension culture.” J Appl Physiol (1985) 93, no. 6 (December 2002): 2171–80. https://doi.org/10.1152/japplphysiol.01087.2001.
       Full Text  Link to Item
    • Wilson, James W., Rajee Ramamurthy, Steffen Porwollik, Michael McClelland, Timothy Hammond, Pat Allen, C Mark Ott, Duane L. Pierson, and Cheryl A. Nickerson. “Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.” Proc Natl Acad Sci U S A 99, no. 21 (October 15, 2002): 13807–12. https://doi.org/10.1073/pnas.212387899.
       Full Text  Link to Item
    • Saban, Marcia R., Ngoc-Bich Nguyen, Timothy G. Hammond, and Ricardo Saban. “Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.” Am J Pathol 160, no. 6 (June 2002): 2095–2110. https://doi.org/10.1016/S0002-9440(10)61159-5.
       Full Text  Link to Item
    • Cowger, Nancy L., Edmund Benes, Patricia L. Allen, and Timothy G. Hammond. “Expression of renal cell protein markers is dependent on initial mechanical culture conditions.” J Appl Physiol (1985) 92, no. 2 (February 2002): 691–700. https://doi.org/10.1152/jappl.2002.92.2.691.
       Full Text  Link to Item
    • Saban, M. R., R. Saban, T. G. Hammond, M. Haak-Frendscho, H. Steinberg, M. W. Tengowski, and D. E. Bjorling. “LPS-sensory peptide communication in experimental cystitis.” Am J Physiol Renal Physiol 282, no. 2 (February 2002): F202–10. https://doi.org/10.1152/ajprenal.0163.2001.
       Full Text  Link to Item
    • Saban, R., M. R. Saban, N. B. Nguyen, T. G. Hammond, and B. K. Wershil. “Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice.” Physiological Genomics 2002, no. 7 (January 1, 2002): 35–43.
    • Zhuo, Jia L., John D. Imig, Timothy G. Hammond, Sheyla Orengo, Edmund Benes, and L Gabriel Navar. “Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.” Hypertension 39, no. 1 (January 2002): 116–21. https://doi.org/10.1161/hy0102.100780.
       Full Text  Link to Item
    • Hammond, T. G., L. A. Cubano, J. Love, T. Baker, T. J. Goodwin, and P. L. Alien. “Mechanical culture conditions effect gene expression.” 2001 Conference and Exhibit on International Space Station Utilization, December 1, 2001.
    • Jo, I., D. T. Ward, M. A. Baum, J. D. Scott, V. M. Coghlan, T. G. Hammond, and H. W. Harris. “AQP2 is a substrate for endogenous PP2B activity within an inner medullary AKAP-signaling complex.” Am J Physiol Renal Physiol 281, no. 5 (November 2001): F958–65. https://doi.org/10.1152/ajprenal.2001.281.5.F958.
       Full Text  Link to Item
    • Nickerson, C. A., T. J. Goodwin, J. Terlonge, C. M. Ott, K. L. Buchanan, W. C. Uicker, K. Emami, et al. “Three-dimensional tissue assemblies: novel models for the study of Salmonella enterica serovar Typhimurium pathogenesis.” Infect Immun 69, no. 11 (November 2001): 7106–20. https://doi.org/10.1128/IAI.69.11.7106-7120.2001.
       Full Text  Link to Item
    • Saban, R., M. R. Saban, N. B. Nguyen, T. G. Hammond, and B. K. Wershil. “Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice.” Physiol Genomics 7, no. 1 (October 10, 2001): 35–43. https://doi.org/10.1152/physiolgenomics.00044.2001.
       Full Text  Link to Item
    • Hammond, T. G., and J. M. Hammond. “Optimized suspension culture: the rotating-wall vessel.” Am J Physiol Renal Physiol 281, no. 1 (July 2001): F12–25. https://doi.org/10.1152/ajprenal.2001.281.1.F12.
       Full Text  Link to Item
    • Saban, M. R., N. B. Nguyen, T. G. Hammond, and R. Saban. “cDNA array of lipopolysaccharide-induced bladder gene expression.” Urology 57, no. 6 Suppl 1 (June 2001): 117. https://doi.org/10.1016/s0090-4295(01)01064-0.
       Full Text  Link to Item
    • Wang, X. C., J. H. Kaysen, R. Saban, P. L. Allen, E. N. Benses, and T. G. Hammond. “cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis.” Urology 57, no. 6 Suppl 1 (June 2001): 114–15. https://doi.org/10.1016/s0090-4295(01)01056-1.
       Full Text  Link to Item
    • Saban, M. R., H. Hellmich, N. B. Nguyen, J. Winston, T. G. Hammond, and R. Saban. “Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation.” Physiol Genomics 5, no. 3 (April 2, 2001): 147–60. https://doi.org/10.1152/physiolgenomics.2001.5.3.147.
       Full Text  Link to Item
    • DeLucas, L. J., R. J. Bula, T. Hammond, and N. R. Pellis. “A review of microgravity biotechnology.” 38th Aerospace Sciences Meeting and Exhibit, December 1, 2000.
    • Goodwin, T. J., L. Coate-Li, R. M. Linnehan, and T. G. Hammond. “Selected contribution: a three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue.” J Appl Physiol (1985) 89, no. 6 (December 2000): 2508–17. https://doi.org/10.1152/jappl.2000.89.6.2508.
       Full Text  Link to Item
    • Hammond, T. G., E. Benes, K. C. O’Reilly, D. A. Wolf, R. M. Linnehan, A. Taher, J. H. Kaysen, P. L. Allen, and T. J. Goodwin. “Mechanical culture conditions effect gene expression: gravity-induced changes on the space shuttle.” Physiol Genomics 3, no. 3 (September 8, 2000): 163–73. https://doi.org/10.1152/physiolgenomics.2000.3.3.163.
       Full Text  Link to Item
    • Hammond, T. G., R. Saban, K. L. Bost, H. W. Harris, J. H. Kaysen, F. O. Goda, X. C. Wang, et al. “Substance P dependence of endosomal fusion during bladder inflammation.” Am J Physiol Renal Physiol 278, no. 3 (March 2000): F440–51. https://doi.org/10.1152/ajprenal.2000.278.3.F440.
       Full Text  Link to Item
    • Saban, R., M. R. Saban, N. B. Nguyen, B. Lu, C. Gerard, N. P. Gerard, and T. G. Hammond. “Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis.” Am J Pathol 156, no. 3 (March 2000): 775–80. https://doi.org/10.1016/S0002-9440(10)64944-9.
       Full Text  Link to Item
    • Wang, X. C., R. Saban, J. H. Kaysen, M. R. Saban, P. L. Allen, E. N. Benes, and T. G. Hammond. “Nuclear factor kappa B mediates lipopolysaccharide-induced inflammation in the urinary bladder.” J Urol 163, no. 3 (March 2000): 993–98.
       Link to Item
    • Verroust, P. J., R. Kozyraki, T. G. Hammond, S. K. Moestrup, and E. I. Christensen. “Physiopathologic role of cubilin and megalin.” Adv Nephrol Necker Hosp 30 (2000): 127–45.
       Link to Item
    • Imig, J. D., G. L. Navar, L. X. Zou, K. C. O’Reilly, P. L. Allen, J. H. Kaysen, T. G. Hammond, and L. G. Navar. “Renal endosomes contain angiotensin peptides, converting enzyme, and AT(1A) receptors.” Am J Physiol 277, no. 2 (August 1999): F303–11. https://doi.org/10.1152/ajprenal.1999.277.2.F303.
       Full Text  Link to Item
    • Hammond, T. G., F. C. Lewis, T. J. Goodwin, R. M. Linnehan, D. A. Wolf, K. P. Hire, W. C. Campbell, et al. “Gene expression in space.” Nat Med 5, no. 4 (April 1999): 359. https://doi.org/10.1038/7331.
       Full Text  Link to Item
    • Marriott, I., T. G. Hammond, E. K. Thomas, and K. L. Bost. “Salmonella efficiently enter and survive within cultured CD11c+ dendritic cells initiating cytokine expression.” Eur J Immunol 29, no. 4 (April 1999): 1107–15. https://doi.org/10.1002/(SICI)1521-4141(199904)29:04<1107::AID-IMMU1107>3.0.CO;2-0.
       Full Text  Link to Item
    • Kaysen, J. H., W. C. Campbell, R. R. Majewski, F. O. Goda, G. L. Navar, F. C. Lewis, T. J. Goodwin, and T. G. Hammond. “Select de novo gene and protein expression during renal epithelial cell culture in rotating wall vessels is shear stress dependent.” J Membr Biol 168, no. 1 (March 1, 1999): 77–89. https://doi.org/10.1007/s002329900499.
       Full Text  Link to Item
    • Cowger, N. L., K. C. O’Connor, T. G. Hammond, D. J. Lacks, and G. L. Navar. “Characterization of bimodal cell death of insect cells in a rotating- wall vessel and shaker flask.” Biotechnology and Bioengineering 64, no. 1 (1999): 14–26. https://doi.org/10.1002/(SICI)1097-0290(19990705)64:1<14::AID-BIT2>3.0.CO;2-R.
       Full Text
    • Hammond, T. G., A. Hu, J. M. Hammond, M. V. Relling, and J. L. Underwood. “Detection of point mutations on a DNA microchip.” Clinical Immunology Newsletter 19, no. 12 (January 1, 1999): 121–26. https://doi.org/10.1016/S0197-1859(00)88685-9.
       Full Text
    • Ward, D. T., T. G. Hammond, and H. W. Harris. “Modulation of vasopressin-elicited water transport by trafficking of aquaporin2-containing vesicles.” Annu Rev Physiol 61 (1999): 683–97. https://doi.org/10.1146/annurev.physiol.61.1.683.
       Full Text  Link to Item
    • Busser, B. W., T. G. Hammond, D. E. Bjorling, and R. Saban. “Lipopolysaccharide upregulates bradykinin 1 receptors in the isolated mouse bladder.” J Urol 160, no. 6 Pt 1 (December 1998): 2267–73. https://doi.org/10.1097/00005392-199812010-00098.
       Full Text  Link to Item
    • Ortiz, L. A., K. Moroz, J. Y. Liu, G. W. Hoyle, T. Hammond, R. F. Hamilton, A. Holian, W. Banks, A. R. Brody, and M. Friedman. “Alveolar macrophage apoptosis and TNF-alpha, but not p53, expression correlate with murine response to bleomycin.” Am J Physiol 275, no. 6 (December 1998): L1208–18. https://doi.org/10.1152/ajplung.1998.275.6.L1208.
       Full Text  Link to Item
    • Burow, M. E., C. B. Weldon, Y. Tang, G. L. Navar, S. Krajewski, J. C. Reed, T. G. Hammond, S. Clejan, and B. S. Beckman. “Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.” Cancer Res 58, no. 21 (November 1, 1998): 4940–46.
       Link to Item
    • Luyckx, V. A., F. O. Goda, D. B. Mount, T. Nishio, A. Hall, S. C. Hebert, T. G. Hammond, and A. S. Yu. “Intrarenal and subcellular localization of rat CLC5.” Am J Physiol 275, no. 5 (November 1998): F761–69. https://doi.org/10.1152/ajprenal.1998.275.5.F761.
       Full Text  Link to Item
    • Batuman, V., P. J. Verroust, G. L. Navar, J. H. Kaysen, F. O. Goda, W. C. Campbell, E. Simon, et al. “Myeloma light chains are ligands for cubilin (gp280).” Am J Physiol 275, no. 2 (August 1998): F246–54. https://doi.org/10.1152/ajprenal.1998.275.2.F246.
       Full Text  Link to Item
    • Hammond, T. G., F. O. Goda, G. L. Navar, W. C. Campbell, R. R. Majewski, D. L. Galvan, F. Pontillon, et al. “Membrane potential mediates H(+)-ATPase dependence of "degradative pathway" endosomal fusion.” J Membr Biol 162, no. 2 (March 15, 1998): 157–67. https://doi.org/10.1007/s002329900353.
       Full Text  Link to Item
    • Moestrup, S. K., R. Kozyraki, M. Kristiansen, J. H. Kaysen, H. H. Rasmussen, D. Brault, F. Pontillon, et al. “The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.” J Biol Chem 273, no. 9 (February 27, 1998): 5235–42. https://doi.org/10.1074/jbc.273.9.5235.
       Full Text  Link to Item
    • Lockyer, J. M., J. S. Colladay, W. L. Alperin-Lea, T. Hammond, and A. J. Buda. “Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells.” Circ Res 82, no. 3 (February 23, 1998): 314–20. https://doi.org/10.1161/01.res.82.3.314.
       Full Text  Link to Item
    • Saban, R., T. G. Hammond, B. W. Busser, and D. E. Bjorling. “Lipopolysaccharide (LPS) Upregulates Bradykinin 1 (BK1) receptors in the isolated mouse bladder.” Faseb Journal 12, no. 4 (1998): A570.
    • Hammond, T. G., R. R. Majewski, J. H. Kaysen, F. O. Goda, G. L. Navar, F. Pontillon, and P. J. Verroust. “Gentamicin inhibits rat renal cortical homotypic endosomal fusion: Role of megalin.” American Journal of Physiology 272, no. 1 PART 2 (December 1, 1997).
    • Seetharam, B., E. I. Christensen, S. K. Moestrup, T. G. Hammond, and P. J. Verroust. “Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.” J Clin Invest 99, no. 10 (May 15, 1997): 2317–22. https://doi.org/10.1172/JCI119411.
       Full Text  Link to Item
    • Hammond, T. G., R. R. Majewski, J. H. Kaysen, F. O. Goda, G. L. Navar, F. Pontillon, and P. J. Verroust. “Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin.” Am J Physiol 272, no. 1 Pt 2 (January 1997): F117–23. https://doi.org/10.1152/ajprenal.1997.272.1.F117.
       Full Text  Link to Item
    • Hammond, T. G., M. L. Zeidel, M. L. De Biorling, M. R. Saban, and R. Safaan. “Neurokinin-1 (substance p) receptor mediated inhibition of endosomal fusion in transitional epithelial cells during acute urinary bladder inflammation.” Faseb Journal 10, no. 6 (December 1, 1996).
    • Verroust, P. J., E. I. Christensen, and T. G. Hammond. “[Vesicular flow in epithelial cells: physiopathologic importance of two multiligand receptors].” Bull Acad Natl Med 180, no. 6 (June 1996): 1187–97.
       Link to Item
    • Siner, J., A. Paredes, C. Hosselet, T. Hammond, K. Strange, and H. W. Harris. “Cloning of an aquaporin homologue present in water channel containing endosomes of toad urinary bladder.” Am J Physiol 270, no. 1 Pt 1 (January 1996): C372–81. https://doi.org/10.1152/ajpcell.1996.270.1.C372.
       Full Text  Link to Item
    • Verroust, P. J., E. I. Christensen, and T. G. Hammond. “[Endocytosis and receptors: molecular and physiological aspects].” Nephrologie 17, no. 7 (1996): 359–64.
       Link to Item
    • Bose, S., S. Seetharam, T. G. Hammond, and B. Seetharam. “Regulation of expression of transcobalamin II receptor in the rat.” Biochem J 310 ( Pt 3) (September 15, 1995): 923–29. https://doi.org/10.1042/bj3100923.
       Full Text  Link to Item
    • Christensen, E. I., S. Nielsen, S. K. Moestrup, C. Borre, A. B. Maunsbach, E. de Heer, P. Ronco, T. G. Hammond, and P. Verroust. “Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules.” Eur J Cell Biol 66, no. 4 (April 1995): 349–64.
       Link to Item
    • Jo, I., H. W. Harris, A. M. Amendt-Raduege, R. R. Majewski, and T. G. Hammond. “Rat kidney papilla contains abundant synaptobrevin protein that participates in the fusion of antidiuretic hormone-regulated water channel-containing endosomes in vitro.” Proc Natl Acad Sci U S A 92, no. 6 (March 14, 1995): 1876–80. https://doi.org/10.1073/pnas.92.6.1876.
       Full Text  Link to Item
    • Hammond, T. G., R. R. Majewski, K. E. Muse, T. D. Oberley, L. W. Morrissey, and A. M. Amendt-Raduege. “Energy transfer assays of rat renal cortical endosomal fusion: evidence for superfusion.” Am J Physiol 267, no. 6 Pt 2 (December 1994): F1021–33. https://doi.org/10.1152/ajprenal.1994.267.6.F1021.
       Full Text  Link to Item
    • Hammond, T. G., R. R. Majewski, K. E. Muse, T. D. Oberley, L. W. Morrissey, and A. M. Amendt-Raduege. “Energy transfer assays of rat renal cortical endosomal fusion: Evidence for superfusion.” Am.J.Physiol. 267, no. 6 part 2 (December 1, 1994).
    • Chang, A., T. G. Hammond, T. T. Sun, and M. L. Zeidel. “Permeability properties of the mammalian bladder apical membrane.” Am J Physiol 267, no. 5 Pt 1 (November 1994): C1483–92. https://doi.org/10.1152/ajpcell.1994.267.5.C1483.
       Full Text  Link to Item
    • Hammond, T. G., P. J. Verroust, R. R. Majewski, K. E. Muse, and T. D. Oberley. “Heavy endosomes isolated from the rat renal cortex show attributes of intermicrovillar clefts.” Am J Physiol 267, no. 4 Pt 2 (October 1994): F516–27. https://doi.org/10.1152/ajprenal.1994.267.4.F516.
       Full Text  Link to Item
    • Hammond, T. G., and P. J. Verroust. “Heterogeneity of endosomal populations in the rat renal cortex: light endosomes.” Am J Physiol 266, no. 6 Pt 1 (June 1994): C1783–94. https://doi.org/10.1152/ajpcell.1994.266.6.C1783.
       Full Text  Link to Item
    • Morré, D. J., J. Lawrence, K. Safranski, T. Hammond, and D. M. Morré. “Experimental basis for separation of membrane vesicles by preparative free-flow electrophoresis.” J Chromatogr A 668, no. 1 (May 6, 1994): 201–13. https://doi.org/10.1016/0021-9673(94)80110-X.
       Full Text  Link to Item
    • Lee, F. T., K. M. Leahy-Gross, T. G. Hammond, M. J. Wakeen, and S. W. Zimmerman. “Pneumoperitoneum in peritoneal dialysis patients: significance of diagnosis by CT.” J Comput Assist Tomogr 18, no. 3 (May 1994): 439–42. https://doi.org/10.1097/00004728-199405000-00018.
       Full Text  Link to Item
    • Harris, H. W., M. L. Zeidel, I. Jo, and T. G. Hammond. “Characterization of purified endosomes containing the antidiuretic hormone-sensitive water channel from rat renal papilla.” J Biol Chem 269, no. 16 (April 22, 1994): 11993–0.
       Link to Item
    • Hammond, T. G., and P. J. Verroust. “Trafficking of apical proteins into clathrin-coated vesicles isolated from rat renal cortex.” Am J Physiol 266, no. 4 Pt 2 (April 1994): F554–62. https://doi.org/10.1152/ajprenal.1994.266.4.F554.
       Full Text  Link to Item
    • Hammond, T. G., P. J. Verroust, R. R. Majewski, K. E. Muse, and T. D. Oberley. “Heavy endosomes isolated from the rat renal cortex show attributes of intermicrovillar clefts.” Am.J.Physiol. 267, no. 4 part 2 (January 1, 1994).
    • Hammond, T. G., and P. J. Verroust. “Heterogeneity of endosomal populations in the rat renal cortex: Light endosomes.” Am.J.Physiol. 266, no. 6 part 1 (January 1, 1994).
    • Hammond, T. G., and P. J. Verroust. “Trafficking of apical proteins into clathri-coated vesicles isolated from rat renal cortex.” Am.J.Physiol. 266, no. 4 part 2 (January 1, 1994).
    • Piqueras, A. I., M. Somers, T. G. Hammond, K. Strange, H. W. Harris Jnr, M. Gawryl, and M. L. Zeidel. “Permeability properties of rat renal lysosomes.” Am.J.Physiol. 266, no. 1 part 1 (January 1, 1994).
    • Piqueras, A. I., M. Somers, T. G. Hammond, K. Strange, H. W. Harris, M. Gawryl, and M. L. Zeidel. “Permeability properties of rat renal lysosomes.” Am J Physiol 266, no. 1 Pt 1 (January 1994): C121–33. https://doi.org/10.1152/ajpcell.1994.266.1.C121.
       Full Text  Link to Item
    • Hammond, T. G., D. J. Morré, H. W. Harris, and M. L. Zeidel. “Isolation of highly purified, functional endosomes from toad urinary bladder.” Biochem J 295 ( Pt 2) (October 15, 1993): 471–76. https://doi.org/10.1042/bj2950471.
       Full Text  Link to Item
    • Zeidel, M. L., T. G. Hammond, J. B. Wade, J. Tucker, and H. W. Harris. “Fate of antidiuretic hormone water channel proteins after retrieval from apical membrane.” Am J Physiol 265, no. 3 Pt 1 (September 1993): C822–33. https://doi.org/10.1152/ajpcell.1993.265.3.C822.
       Full Text  Link to Item
    • Hammond, T. G., R. R. Majewski, J. J. Onorato, P. C. Brazy, and D. J. Morré. “Isolation and characterization of renal cortical membranes using an aqueous two-phase partition technique.” Biochem J 292 ( Pt 3) (June 15, 1993): 743–48. https://doi.org/10.1042/bj2920743.
       Full Text  Link to Item
    • Ateshkadi, A., C. A. Johnson, L. L. Oxton, T. G. Hammond, W. S. Bohenek, and S. W. Zimmerman. “Pharmacokinetics of intraperitoneal, intravenous, and subcutaneous recombinant human erythropoietin in patients on continuous ambulatory peritoneal dialysis.” Am J Kidney Dis 21, no. 6 (June 1993): 635–42. https://doi.org/10.1016/s0272-6386(12)80037-0.
       Full Text  Link to Item
    • Hammond, T. G., R. R. Majewski, D. J. Morré, K. Schell, and L. W. Morrissey. “Forward scatter pulse width signals resolve multiple populations of endosomes.” Cytometry 14, no. 4 (1993): 411–20. https://doi.org/10.1002/cyto.990140410.
       Full Text  Link to Item
    • Hammond, T. G. “Analysis and isolation of renal tubular cells by flow cytometry.” Kidney Int 42, no. 4 (October 1992): 997–1005. https://doi.org/10.1038/ki.1992.379.
       Full Text  Link to Item
    • Zeidel, M. L., T. Hammond, B. Botelho, and H. W. Harris. “Functional and structural characterization of endosomes from toad bladder epithelial cells.” Am J Physiol 263, no. 1 Pt 2 (July 1992): F62–76. https://doi.org/10.1152/ajprenal.1992.263.1.F62.
       Full Text  Link to Item
    • Hammond, T. G. “Study of rat renal brush border membrane vesicles by flow cytometry.” Kidney Int 38, no. 1 (July 1990): 5–11. https://doi.org/10.1038/ki.1990.160.
       Full Text  Link to Item
    • Hammond, T. G., and M. W. Mosesson. “Fatal small-bowel necrosis and pulmonary hypertension in sickle cell disease.” Arch Intern Med 149, no. 2 (February 1989): 447–48.
       Link to Item
    • Yusufi, A. N., T. G. Hammond, T. P. Dousa, and F. G. Knox. “Effect of atrial natriuretic factor on brush border membrane transport of phosphate in phosphate-deprived rats.” Biochem Pharmacol 37, no. 20 (October 15, 1988): 4027–29. https://doi.org/10.1016/0006-2952(88)90089-5.
       Full Text  Link to Item
    • Ruilope, L. M., B. Miranda, R. G. Robles, T. G. Hammond, J. Sancho, J. C. Romero, and J. L. Rodicio. “Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension.” Postgrad Med J 62 Suppl 1 (1986): 90–93.
       Link to Item
    • Hammond, T. G., A. Haramati, and F. G. Knox. “Synthetic atrial natriuretic factor decreases renal tubular phosphate reabsorption in rats.” American Journal of Physiology  Renal Fluid and Electrolyte Physiology 18, no. 2 (December 1, 1985).
    • Hammond, T. G., A. Haramati, and F. G. Knox. “Synthetic atrial natriuretic factor decreases renal tubular phosphate reabsorption in rats.” Am J Physiol 249, no. 2 Pt 2 (August 1985): F315–18. https://doi.org/10.1152/ajprenal.1985.249.2.F315.
       Full Text  Link to Item
    • Hammond, T. G., A. N. Yusufi, F. G. Knox, and T. P. Dousa. “Administration of atrial natriuretic factor inhibits sodium-coupled transport in proximal tubules.” J Clin Invest 75, no. 6 (June 1985): 1983–89. https://doi.org/10.1172/JCI111916.
       Full Text  Link to Item
    • Ruilope, L., C. Paya, J. M. Alcazar, J. Sancho-Rof, R. Garcia-Robles, J. Rodicio, T. G. Hammond, F. G. Knox, and J. C. Romero. “Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women.” J Hypertens Suppl 2, no. 3 (December 1984): S251–54.
       Link to Item
    • Haas, J. A., T. G. Hammond, J. P. Granger, E. H. Blaine, and F. G. Knox. “Mechanism of natriuresis during intrarenal infusion of prostaglandins.” Am J Physiol 247, no. 3 Pt 2 (September 1984): F475–79. https://doi.org/10.1152/ajprenal.1984.247.3.F475.
       Full Text  Link to Item
    • Hammond, T. G., J. A. Whitworth, D. Saines, R. Thatcher, J. Andrews, and P. Kincaid-Smith. “Renin-angiotensin-aldosterone system in nephrotic syndrome.” Am J Kidney Dis 4, no. 1 (July 1984): 18–23. https://doi.org/10.1016/s0272-6386(84)80021-9.
       Full Text  Link to Item
    • Haas, J. A., T. G. Hammond, and J. P. Granger. “Mechanism of natriuresis during intrarenal infusion of prostaglandins.” American Journal of Physiology  Renal Fluid and Electrolyte Physiology 16, no. 3 (January 1, 1984).
    • Keiser, J. A., T. G. Hammond, and J. C. Romero. “Angiotensin II blockade during thoracic inferior vena cava (TIVC) constriction.” Federation Proceedings 43, no. 3 (January 1, 1984).
    • Hammond, T. G., J. D. Buchanan, B. A. Scoggins, R. Thatcher, and J. A. Whitworth. “Primary hyperaldosteronism in pregnancy.” Aust N Z J Med 12, no. 5 (October 1982): 537–39. https://doi.org/10.1111/j.1445-5994.1982.tb03842.x.
       Full Text  Link to Item
    • Whitworth, J. A., T. G. Hammond, K. W. Stewart, R. T. Mason, E. G. Schneider, D. A. Denton, J. P. Coghlan, and B. A. Scoggins. “Effects of converting enzyme inhibition with captopril on renal function in normal and ACTH treated sheep.” Clin Exp Pharmacol Physiol 9, no. 5 (September 1982): 505–9. https://doi.org/10.1111/j.1440-1681.1982.tb00825.x.
       Full Text  Link to Item
    • McDougall, J. G., J. P. Coghlan, D. A. Denton, D. T. Fei, T. G. Hammond, K. J. Hardy, S. J. Potocnik, B. A. Scoggins, and R. D. Wright. “Renal autotransplants in sheep: investigation of renal function and renovascular hypertension.” Clin Exp Pharmacol Physiol 8, no. 5 (September 1981): 497–501. https://doi.org/10.1111/j.1440-1681.1981.tb00756.x.
       Full Text  Link to Item
    • Hammond, T. G., and J. A. Whitworth. “Adverse reactions to ginseng.” Med J Aust 1, no. 9 (May 2, 1981): 492. https://doi.org/10.5694/j.1326-5377.1981.tb135752.x.
       Full Text  Link to Item

  • Conference Papers

    • DeLucas, L. J., R. J. Bula, T. Hammond, and N. R. Pellis. “A review of microgravity biotechnology.” In 38th Aerospace Sciences Meeting and Exhibit, 2000. https://doi.org/10.2514/6.2000-1056.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.