Scholars@Duke
Tina Dinesh Tailor

Tina Dinesh Tailor

Associate Professor of Radiology
Radiology, Cardiothoracic Imaging

Selected Publications

Concordance-based Predictive Uncertainty (CPU)-Index: Proof-of-concept with application towards improved specificity of lung cancers on low dose screening CT.

Journal Article Artif Intell Med · February 2025 In this paper, we introduce a novel concordance-based predictive uncertainty (CPU)-Index, which integrates insights from subgroup analysis and personalized AI time-to-event models. Through its application in refining lung cancer screening (LCS) predictions ... Full text Link to item Cite

The parenthood journey in radiology: Challenges and opportunities.

Journal Article Curr Probl Diagn Radiol · 2025 The journey to parenthood is often delayed or prolonged for physicians, which disproportionately negatively impact women physicians. Women radiologists may delay childbearing for many reasons, which may lead to higher rates of regret and greater risks of i ... Full text Link to item Cite

The 2023 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Management of subsolid lung nodules.

Journal Article J Thorac Cardiovasc Surg · September 2024 OBJECTIVE: Lung cancers that present as radiographic subsolid nodules represent a subtype with distinct biological behavior and outcomes. The objective of this document is to review the existing literature and report consensus among a group of multidiscipl ... Full text Link to item Cite

ACR Appropriateness Criteria® Preprocedural Planning for Left Atrial Procedures in Atrial Fibrillation.

Journal Article J Am Coll Radiol · June 2024 This document summarizes the relevant literature for the selection of preprocedural imaging in three clinical scenarios in patients needing endovascular treatment or cardioversion of atrial fibrillation. These clinical scenarios include preprocedural imagi ... Full text Link to item Cite

Lung Cancer Screening in Clinical Practice: A 5-Year Review of Frequency and Predictors of Lung Cancer in the Screened Population.

Journal Article J Am Coll Radiol · May 2024 PURPOSE: The aims of this study were to evaluate (1) frequency, type, and lung cancer stage in a clinical lung cancer screening (LCS) population and (2) the association between patient characteristics and Lung CT Screening Reporting & Data System (Lung-RAD ... Full text Link to item Cite

Historical Perspective on Lung Cancer Screening.

Journal Article Thorac Surg Clin · November 2023 Lung cancer represents a large burden on society with a staggering incidence and mortality rate that has steadily increased until recently. The impetus to design an effective screening program for the deadliest cancer in the United States and worldwide beg ... Full text Link to item Cite

The Impact of Downstream Procedures on Lung Cancer Screening Adherence.

Journal Article J Am Coll Radiol · October 2023 OBJECTIVE: (1) Evaluate downstream procedures after lung cancer screening (LCS), including imaging and invasive procedures, in screened individuals without screen-detected lung cancer. (2) Determine the association between repeat LCS and downstream procedu ... Full text Link to item Cite

Image quality of photon counting and energy integrating chest CT - Prospective head-to-head comparison on same patients.

Journal Article Eur J Radiol · September 2023 PURPOSE: To prospectively compare the image quality of high-resolution, low-dose photon-counting detector CT (PCD-CT) with standard energy-integrating-detector CT (EID) on the same patients. METHOD: IRB-approved, prospective study; patients received same-d ... Full text Open Access Link to item Cite

Significant Incidental Findings in the National Lung Screening Trial.

Journal Article JAMA Intern Med · July 1, 2023 IMPORTANCE: Low-dose computed tomography (LDCT) lung screening has been shown to reduce lung cancer mortality. Significant incidental findings (SIFs) have been widely reported in patients undergoing LDCT lung screening. However, the exact nature of these S ... Full text Link to item Cite

Socioeconomic disparities in immunotherapy use among advanced-stage non-small cell lung cancer patients: analysis of the National Cancer Database.

Journal Article Sci Rep · May 20, 2023 Socioeconomic and racial disparities exist in access to care among patients with non-small cell lung cancer (NSCLC) in the United States. Immunotherapy is a widely established treatment modality for patients with advanced-stage NSCLC (aNSCLC). We examined ... Full text Link to item Cite

Racial and ethnic inequities of palliative care use among advanced Non-Small cell lung cancer patients in the US.

Journal Article Cancer Med · April 2023 BACKGROUND: With early intervention, palliative care (PC) can improve quality of life and increase survival among advanced-stage non-small cell lung cancer (aNCSLC) patients. However, PC is often offered late in the cancer treatment course and is underused ... Full text Link to item Cite

Repeat Annual Lung Cancer Screening After Baseline Screening Among Screen-Negative Individuals: No-Cost Coverage Is Not Enough.

Journal Article J Am Coll Radiol · January 2023 PURPOSE: Adherence to lung cancer screening (LCS) is central to effective screening. The authors evaluated the likelihood of repeat annual LCS in a national commercially insured population and associations with individual characteristics, insurance charact ... Full text Link to item Cite

Coronary Artery Calcium Evaluation Using New Generation Photon-counting Computed Tomography Yields Lower Radiation Dose Compared With Standard Computed Tomography.

Journal Article J Thorac Imaging · January 1, 2023 Prospective head-to-head comparison of coronary calcium scores between standard computed tomography (CT) and photon-counting CT show no significant differences, while photon-counting CT administers substantially lower radiation dose. ... Full text Link to item Cite

Prospective Multisite Cohort Study to Evaluate Shared Decision-Making Utilization Among Individuals Screened for Lung Cancer.

Journal Article J Am Coll Radiol · August 2022 PURPOSE: The aim of this study was to determine the frequency, components of, and factors associated with shared decision-making (SDM) discussions according to electronic health record (EHR) documentation among individuals undergoing lung cancer screening ... Full text Link to item Cite

Racial Differences in Survival Among Advanced-stage Non-small-Cell Lung Cancer Patients Who Received Immunotherapy: An Analysis of the US National Cancer Database (NCDB).

Journal Article J Immunother · February 2022 Lung cancer is the most common cause of cancer death among men and women in the United States, with significant racial disparities in survival. It is unclear whether these disparities persist upon equal utilization of immunotherapy. The purpose of this stu ... Full text Link to item Cite

Total and Out-of-Pocket Costs of Procedures After Lung Cancer Screening in a National Commercially Insured Population: Estimating an Episode of Care.

Journal Article J Am Coll Radiol · January 2022 OBJECTIVE: Consequences of lung cancer screening (LCS) with low-dose chest CT in clinical settings, including procedures, costs, and complications, are incompletely understood. We evaluated downstream invasive procedures after LCS, total and out-of-pocket ... Full text Link to item Cite

Cardiovascular Risk in the Lung Cancer Screening Population: A Multicenter Study Evaluating the Association Between Coronary Artery Calcification and Preventive Statin Prescription.

Journal Article J Am Coll Radiol · September 2021 OBJECTIVE: Coronary artery calcification (CAC) is a marker of atherosclerotic cardiovascular disease (ASCVD), the leading cause of death in individuals receiving lung cancer screening (LCS) with low-dose CT. Our purpose was to determine the proportion of t ... Full text Link to item Cite

Immunotherapy Utilization Among Patients With Metastatic NSCLC: Impact of Comorbidities.

Journal Article J Immunother · June 1, 2021 In patients with metastatic non-small cell lung cancer (mNSCLC), the extent to which immunotherapy utilization rate varies by comorbidities is unclear. Using the National Cancer Database from 2015 to 2016, we assessed the association between levels of como ... Full text Link to item Cite

Changes in Current Procedural Terminology Coding and Its Effect on Specialty-Level Utilization of Musculoskeletal Ultrasound.

Journal Article Current problems in diagnostic radiology · May 2021 PurposeConcerns regarding increasing utilization of non-vascular extremity ultrasound (US) imaging led to the Current Procedural Terminology (CPT) Editorial Panel separating a singular billing code into distinct comprehensive and focused examinati ... Full text Cite

The art of imaging methods—using cutting edge radiological technology to uncover the secrets of ancient anatomical figurines

Journal Article Archaeological and Anthropological Sciences · May 1, 2021 Ivory anatomical figurines are thought to have been carved in Germany in the seventeenth or eighteenth century. While it is speculated that these figurines were used for the study of medical education, little is known about their origins. A precise underst ... Full text Cite

Multimodality cardiac imaging in the 21st century: evolution, advances and future opportunities for innovation.

Journal Article Br J Radiol · January 1, 2021 Cardiovascular imaging has significantly evolved since the turn of the century. Progress in the last two decades has been marked by advances in every modality used to image the heart, including echocardiography, cardiac magnetic resonance, cardiac CT and n ... Full text Link to item Cite

Electronic Health Record Documentation of Shared Decision Making in Lung Cancer Screening

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2021 Cite

Lung Cancer Screening Eligibility and Use: A Population Health Perspective of One Community.

Journal Article N C Med J · 2021 BACKGROUND Low-dose chest CT (LDCT) is the only effective screening test for lung cancer. Annual lung cancer screening (LCS) is recommended by the US Preventive Services Task Force (USPSTF) for individuals at high risk for primary lung neoplasm.METHODS We ... Full text Link to item Cite

Utilization of Lung Cancer Screening in the Medicare Fee-for-Service Population.

Journal Article Chest · November 2020 BACKGROUND: A number of organizations, including the US Preventive Services Task Force (USPSTF), recommend lung cancer screening (LCS) with low-dose CT (LDCT) imaging for high-risk current and former smokers. In 2015, Medicare issued a decision to cover LC ... Full text Link to item Cite

Impact of dual energy cardiac CT for metal artefact reduction post aortic valve replacement.

Journal Article Eur J Radiol · August 2020 PURPOSE: Assess image quality of dual-energy (DE) and single-energy (SE) cardiac multi-detector computed tomographic (MDCT) post aortic valve replacement (AVR) on a dual source MDCT scanner. METHODS: Eighty patients with cardiac MDCT acquisitions (ECG gate ... Full text Link to item Cite

Overview and Challenges of Bronchiolar Disorders.

Journal Article Ann Am Thorac Soc · March 2020 Bronchiolar abnormalities are common and can occur in conditions that affect either the large airways or the more distal parenchyma. In this review, we focus on the diagnosis and management of primary bronchiolar disorders, or conditions in which bronchiol ... Full text Link to item Cite

A Geospatial Analysis of Factors Affecting Access to CT Facilities: Implications for Lung Cancer Screening.

Journal Article J Am Coll Radiol · December 2019 OBJECTIVE: The association between access to CT facilities for lung cancer screening and population characteristics is understudied. We aimed to determine the relationship between census tract-level socioeconomic characteristics (SEC) and driving distance ... Full text Link to item Cite

Abstract 4215: Patient and screening characteristics associated with positive lung cancer screening examinations

Conference Cancer Research · July 1, 2019 AbstractIntroduction. The likelihood of having a positive low dose computed tomography (LDCT) lung cancer screening (LCS) examination that requires workup may vary according to patients’ characteristics and ... Full text Cite

Geographic Access to CT for Lung Cancer Screening: A Census Tract-Level Analysis of Cigarette Smoking in the United States and Driving Distance to a CT Facility.

Journal Article J Am Coll Radiol · January 2019 PURPOSE: Spatial access to health care resources is a requisite for utilization. Our purpose was to determine, at a census tract level, the geographic distribution of US smokers and their driving distance to an ACR-accredited CT facility. METHODS: The numb ... Full text Link to item Cite

Whole Exome Sequencing of Cell-Free DNA for Early Lung Cancer: A Pilot Study to Differentiate Benign From Malignant CT-Detected Pulmonary Lesions.

Journal Article Front Oncol · 2019 Introduction: Indeterminate pulmonary lesions (IPL) detected by CT pose a significant clinical challenge, frequently necessitating long-term surveillance or biopsy for diagnosis. In this pilot investigation, we performed whole exome sequencing (WES) of pla ... Full text Link to item Cite

Lung Cancer Screening in Academic and Community Practice: A Tale of Two Cities

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

Correction to: Chest neoplasias(Medical Radiology, 10.1007/174_2017_6)

Book · January 1, 2019 Inadvertently, the chapter was published online with incorrect author affiliation. The author affiliation has been updated in the chapter as below, Tina D. Tailor Department of Radiology, Division of Cardiothoracic Imaging, Duke University Medical Center, ... Full text Cite

Chest neoplasias

Chapter · January 1, 2019 Thoracic neoplasms comprise a spectrum of benign and malignant pathologies. Primary neoplasms of the thoracic may arise from any compartment of the thorax, including the lungs, airways, mediastinum, pleura, and chest wall. CT plays a fundamental role in th ... Full text Cite

Case 260: Endobronchial Posttransplantation Lymphoproliferative Disease.

Journal Article Radiology · December 2018 History A 31-year-old woman with a history of bilateral orthotopic lung transplantation performed 10 months earlier for cystic fibrosis presented for a routine follow-up appointment, with her chief symptom being a cough. The cough started approximately 1 m ... Full text Link to item Cite

A Normal Thyroid by Any Other Name: Linguistic Analysis of Statements Describing a Normal Thyroid Gland from Noncontrast Chest CT Reports.

Journal Article J Am Coll Radiol · November 2018 PURPOSE: To determine the variability and readability of language used in chest CT reports to describe a "normal" thyroid gland. METHODS: Using a semi-automated process, we identified unique sentences or phrases describing a "normal" thyroid gland in 11,35 ... Full text Link to item Cite

Case 260.

Journal Article Radiology · August 2018 History A 31-year-old woman with a history of bilateral orthotopic lung transplantation performed 10 months earlier for cystic fibrosis presented for a routine follow-up appointment, with her chief symptom being a cough. The cough started approximately 1 m ... Full text Link to item Cite

Patient-Centered Radiology Reporting: Using Online Crowdsourcing to Assess the Effectiveness of a Web-Based Interactive Radiology Report.

Journal Article J Am Coll Radiol · November 2017 PURPOSE: The aim of this study was to evaluate the effectiveness of a patient-centered web-based interactive mammography report. METHODS: A survey was distributed on Amazon Mechanical Turk, an online crowdsourcing platform. One hundred ninety-three US wome ... Full text Link to item Cite

Altered Nulling of Myocardium and Blood Pool.

Journal Article J Thorac Imaging · January 2017 Full text Link to item Cite

Imaging of Heart Disease in Women.

Journal Article Radiology · January 2017 Ischemic heart disease is the number one cause of death of women in the United States, accounting for over a quarter of a million annual female deaths. Evidence within the last several decades supports sex-specific differences in the prevalence, symptoms, ... Full text Link to item Cite

Non-dysbaric arterial gas embolism associated with chronic necrotizing pneumonia, bullae and coughing: a case report.

Journal Article Undersea Hyperb Med · 2017 Arterial gas embolism (AGE) can be clinically devastating, and is most often associated with exposure to changes in ambient pressure, medical procedure or congenital malformation. Here we report a case of AGE in a 78-year-old male without these traditional ... Full text Link to item Cite

Dynamic Contrast-Enhanced MR Imaging in Head and Neck Cancer: Techniques and Clinical Applications.

Journal Article AJNR Am J Neuroradiol · April 2016 In the past decade, dynamic contrast-enhanced MR imaging has had an increasing role in assessing the microvascular characteristics of various tumors, including head and neck cancer. Dynamic contrast-enhanced MR imaging allows noninvasive assessment of perm ... Full text Link to item Cite

The Pseudocavitation Sign of Lung Adenocarcinoma: A Distinguishing Feature and Imaging Biomarker of Lepidic Growth.

Journal Article J Thorac Imaging · September 2015 PURPOSE: Our purpose was to evaluate whether pseudocavitation, characterized by round or oval areas of low attenuation in a lesion on computed tomography (CT), can help distinguish adenocarcinoma from other types of non-small cell lung cancer (NSCLC). We a ... Full text Link to item Cite

Case 215: voriconazole-induced periostitis.

Journal Article Radiology · March 2015 History A 74-year-old woman presented with multifocal bone pain, including pain in multiple ribs, bilateral shoulders, and bilateral hips. The pain began several months before presentation and was quite severe, ultimately necessitating control with narcoti ... Full text Link to item Cite

Orbital Metastasis of Undifferentiated/Anaplastic Thyroid Carcinoma.

Journal Article Ophthalmic Plast Reconstr Surg · 2015 A 52-year-old woman presented with decreased vision, diplopia, esotropia, proptosis, and right orbital pain. Clinical examination was suspicious for an orbital mass and additionally revealed a thyroid gland mass. Imaging studies showed an enhancing mass wi ... Full text Link to item Cite

Case 215.

Journal Article Radiology · November 2014 Full text Link to item Cite

A case of nodular fasciitis causing compressive optic neuropathy.

Journal Article Ophthalmic Plast Reconstr Surg · 2014 A 16-year-old girl with worsening vision, new OD visual field deficits, and tumor in right orbital apex underwent biopsy and surgical excision. Orbital imaging revealed an apical tumor causing bony erosion. Histopathology confirmed the diagnosis of nodular ... Full text Link to item Cite

Orbital neoplasms in adults: clinical, radiologic, and pathologic review.

Journal Article Radiographics · October 2013 Orbital neoplasms in adults may be categorized on the basis of location and histologic type. Imaging features of these lesions often reflect their tissue composition. Cavernous malformations (also known as cavernous hemangiomas), although not true neoplasm ... Full text Link to item Cite

Needle embolism in intravenous drug abuse.

Journal Article Radiol Case Rep · 2012 Although intravenous drug users report the breaking of a needle as a relatively common occurrence, central embolism of needle fragments occurs infrequently in the literature. Central needle embolism also poses a conundrum for the radiologist, as the needle ... Full text Link to item Cite

Effect of pazopanib on tumor microenvironment and liposome delivery.

Journal Article Mol Cancer Ther · June 2010 Pathologic angiogenesis creates an abnormal microenvironment in solid tumors, characterized by elevated interstitial fluid pressure (IFP) and hypoxia. Emerging theories suggest that judicious downregulation of proangiogenic signaling pathways may transient ... Full text Link to item Cite

Abstract A7: Targeting the tumor microenvironment via inhibition of VEGF and PDGF to improve liposomal drug delivery in human non-small cell lung cancer xenografts

Conference Molecular Cancer Therapeutics · December 10, 2009 AbstractBackground: Pathological angiogenesis creates an abnormal microenvironment in tumors, characterized by elevated interstitial fluid pressure (IFP) and hypoxia. Judicious attenuation of angiogenic sign ... Full text Cite

Abstract A10: Antiangiogenic therapy (VEGF-R1–3 and PDGFR inhibitor) increases tumor hemoglobin saturation and decreases interstitial pressure, and microvessel density

Conference Molecular Cancer Therapeutics · December 10, 2009 AbstractMethods: We evaluate the effects of pazopanib, a novel multi-targeted tyrosine kinase inhibitor, by examining its effects on tumor oxygenation, interstitial pressure (IFP), and vascularity as compare ... Full text Cite

Chemical and biological applications of digital-microfluidic devices

Journal Article IEEE Design and Test of Computers · January 1, 2007 The advent of digital microfluidic lab-on-a-chip (LoC) technology offers a platform for developing diagnostic applications with the advantages of portability, reduction of the volumes of the sample and reagents, faster analysis times, increased automation, ... Full text Open Access Cite

PENETRATING INJURY FROM PLASTIC AIRSOFT PELLET SHOWS BEAM-HARDENING ARTIFACT ON COMPUTER TOMOGRAPHY.

Journal Article Retin Cases Brief Rep PURPOSE: To describe a case of left eye corneal perforation, cataract, hyphema, and intraocular foreign body after airsoft pellet injury. METHODS: The authors reviewed the medical history and diagnostic imaging of a 12-year-old boy injured by a pellet from ... Full text Link to item Cite