https://orcid.org/0000-0002-5113-8611
Current Duke Appointments & Affiliations
Associate Professor of Medicine
·
2026 - Present
Medicine, Nephrology,
Medicine
Associate Professor in Pathology
·
2026 - Present
Pathology,
Clinical Science Departments
Recent Scholarly Works
Electrical stimulation of the vagus nerve improves amyloid pathology in delirium superimposed on dementia.
Journal article Bioelectron Med · January 16, 2026 BACKGROUND: Delirium and delirium superimposed on dementia (DSD) are common complications affecting patients suffering from ongoing neurodegenerative pathologies. Peripheral surgical trauma can trigger neuroinflammation and ensuing DSD via mechanisms that ... Full text Open Access Link to item CiteProtocol for isolation of endothelial cells from adult mouse brain.
Journal article STAR Protoc · June 20, 2025 Brain endothelial cells (ECs) line blood vessel walls and form the blood-brain barrier (BBB), facilitating interactions between the brain and the periphery. Here, we present a protocol for isolating purified ECs from adult mouse brains using fluorescence-a ... Full text Open Access Link to item CiteAbstract P183: Porcupine Protects The Kidney By Suppressing Tubular Inflammation And Preserving Mitochondrial Integrity
Conference Hypertension · September 2023 Chronic Kidney Disease (CKD) progression may be slowed or stopped with early diagnosis and intervention, so developing novel therapies is paramount. The Wnt acyl transferase porcupine (PORCN) regulates the secretion of all 19 Wnt ligan ... Full text CiteRecent Grants
Impact of hypertension and aging on postoperative delirium
ResearchCo-Principal Investigator · Awarded by National Institute on Aging · 2025 - 2030IL-6 Trans-signaling increases vulnerability to Postoperative Cognitive Decline in Aging and Alzheimers Disease
ResearchCo Investigator · Awarded by University of California - San Francisco · 2024 - 2029The impacts of postoperative delirium on AD progression
FellowshipAdvisor · Awarded by Alzheimer's Association · 2024 - 2027View All Grants
Education
Peking University (China) ·
2010
Ph.D.
Peking University (China) ·
2007
M.S.
Peking University (China) ·
2005
M.D.