Scholars@Duke
Dena L. Toffaletti

Dena L. Toffaletti

Associate Professor in Medicine
Medicine, Infectious Diseases
toffa001@mc.duke.edu
Duke Box 102359, Durham, NC 27710
337 Sands Bldg, Research Drive, Durham, NC 27710

Selected Grants

Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS

ResearchScientist · Awarded by National Institutes of Health · 2025 - 2030

Efficacy, Pharmacokinetics, and Pharmacodynamics of APX2039 in a Rabbit Model of Cryptococcal Meningitis

ResearchScientist · Awarded by Basilea Pharmaceutica International Ltd, Allschwil · 2025 - 2026

Development of genetic tools in Cryptococcus neoformans to chemically validate the GPI-AP (Glycosylphosphatidylinositol-anchored proteins) biosynthetic pathway

ResearchAssistant Research Professor · Awarded by Novartis Institutes for BioMedical Research · 2025 - 2026

BAL2039 Susceptibility Testing of Cryptococcus neoformans

ResearchScientist · Awarded by Basilea Pharmaceutica · 2025 - 2026

Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS

ResearchInvestigator · Awarded by National Institutes of Health · 2011 - 2024

AM-2-19 Efficacy Testing in a Mouse Model of Cryptococcosis

ResearchResearch Scientist · Awarded by Sfunga Therapeutics · 2022 - 2023

Pathobiology of C. neoformans in the Central Nervous System

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 2014 - 2020

Molecular Umbrella-Amphotericin B Conjugates

ResearchAssistant Research Professor · Awarded by Lehigh University · 2012 - 2016

Genetic molecular biology of virulence in C. neoformans

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 1991 - 2008