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Dena L. Toffaletti

Associate Professor in Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710
337 Sands Bldg, Research Drive, Durham, NC 27710

Selected Grants


Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS

ResearchScientist · Awarded by National Institute of Allergy and Infectious Diseases · 2025 - 2030

Efficacy, Pharmacokinetics, and Pharmacodynamics of APX2039 in a Rabbit Model of Cryptococcal Meningitis

ResearchScientist · Awarded by Basilea Pharmaceutica International Ltd, Allschwil · 2025 - 2027

Development of genetic tools in Cryptococcus neoformans to chemically validate the GPI-AP (Glycosylphosphatidylinositol-anchored proteins) biosynthetic pathway

ResearchAssistant Research Professor · Awarded by Novartis Institutes for BioMedical Research · 2025 - 2027

Targeting Hsp90 in cryptococcal fungal pathogenesis

ResearchResearch Scientist · Awarded by University of Toronto · 2024 - 2027

BAL2039 Susceptibility Testing of Cryptococcus neoformans

ResearchScientist · Awarded by Basilea Pharmaceutica · 2025 - 2026

Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS

ResearchInvestigator · Awarded by National Institutes of Health · 2011 - 2024

AM-2-19 Efficacy Testing in a Mouse Model of Cryptococcosis

ResearchResearch Scientist · Awarded by Sfunga Therapeutics · 2022 - 2023

Pathobiology of C. neoformans in the Central Nervous System

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 2014 - 2020

Molecular Umbrella-Amphotericin B Conjugates

ResearchAssistant Research Professor · Awarded by Lehigh University · 2012 - 2016

Genetic molecular biology of virulence in C. neoformans

ResearchAssistant Research Professor · Awarded by National Institutes of Health · 1991 - 2008

External Relationships


  • Werfen (formerly Instrumentation Laboratory)

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.