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Tony Jun Huang

William Bevan Distinguished Professor of Mechanical Engineering and Materials Science
Thomas Lord Department of Mechanical Engineering and Materials Science
330B LSRC, Box 90300, Durham, NC 27708
330B LSRC, Box 90300, Durham, NC 27708

Research Interests


Acoustofluidics, microfluidics, lab-on-a-chip, biomedical micro-electro-mechanical systems (BioMEMS), optofluidics, plasmofluidics.

Selected Grants


Automated High-purity Exosome isolation-based AD diagnostics system (AHEADx)

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2023 - 2028

Acoustofluidics for drug development

ResearchPrincipal Investigator · Awarded by GlaxoSmithKline · 2024 - 2028

Development of an acoustofluidic bioprinter for the fabrication of 3D tissue constructs with single-cell resolution

ResearchPrincipal Investigator · Awarded by Virginia Polytechnic Institute and State University · 2022 - 2026

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026

Harmonic Acoustics for Neighboring cell Dynamic studies (HANDs)

ResearchPrincipal Investigator · Awarded by Brigham and Women's Hospital · 2022 - 2026

Automated High-purity Exosome isolation-based AD diagnostics system (AHEADx)

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2023 - 2028

Acoustofluidics for drug development

ResearchPrincipal Investigator · Awarded by GlaxoSmithKline · 2024 - 2028

Development of an acoustofluidic bioprinter for the fabrication of 3D tissue constructs with single-cell resolution

ResearchPrincipal Investigator · Awarded by Virginia Polytechnic Institute and State University · 2022 - 2026

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026

Harmonic Acoustics for Neighboring cell Dynamic studies (HANDs)

ResearchPrincipal Investigator · Awarded by Brigham and Women's Hospital · 2022 - 2026

Acoustofluidic Separation of Placental Nanovesicle Subpopulations in Obstetrical Diseases

ResearchPrincipal Investigator · Awarded by Magee-Womens Research Institute and Foundation · 2021 - 2026

Collaborative Research: Surface Acoustic Wave Holography Enabled Additive Manufacturing of Multifunctional Composites

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2021 - 2025

Development of a digital acoustofluidic system for automating liquid handling in biomedical research

ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2021 - 2025

An acoustofluidic device for high-resolution 3D imaging and sorting of C. elegans without anesthetics

ResearchCo Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2022 - 2025

Novel development ofan acoustofluidic device for targeted antibody removal in pediatric organ transplan rejection

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2025

Three-Dimensional (3D) Acoustofluidic Scanning Nanoscope with Super Resolution and Large Field of View

ResearchPrincipal Investigator · Awarded by University of Dayton · 2021 - 2024

Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA Biomarkers

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2024

An acoustofluidic device for diagnosing preclinical Alzheimer's disease

ResearchCo Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2022 - 2024

An Acoustofluidic Device for Biocompatible Platelet Separation

ResearchCo Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2022 - 2024

Enabling Efficient, Fast, Biocompatible Exosome Separation via Acoustofluidics

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2024

Acoustofluidic Separation, Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and Biofluids

ResearchCo Investigator · Awarded by University of California - Los Angeles · 2019 - 2023

Structural dynamics and mechanisms of photoreceptor signaling

ResearchPrincipal Investigator · Awarded by University of Minnesota · 2020 - 2023

Acoustic Device to Prevent Antibody Mediated Organ Transplant Failure

ResearchCollaborator · Awarded by Hartwell Foundation · 2019 - 2023

Saliva-based AFS Separation of SARS-CoV-2 for Earliest and Concurrent Detection of Viral RNA, Viral Load and Host Antibody

ResearchPrincipal Investigator · Awarded by University of California - Los Angeles · 2020 - 2022

Collaborative Research: High Resolution Acoustic Manipulation of Single Cells with Integrated MEMS based Phased Arrays

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2018 - 2022

Developing Biomarkers for Traumatic Brain Injury and Alzheimer's Disease via Acoustic Exosome Separation Devices

ResearchPrincipal Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2018 - 2021

Extracellular vesicles and their ncRNAs cargo as markers of trophoblast injury

ResearchPrincipal Investigator · Awarded by Magee-Womens Research Institute and Foundation · 2016 - 2021

Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform

ResearchPrincipal Investigator · Awarded by Northeastern University · 2018 - 2021

An acoustofluidic device for diagnosing preclinical Alzheimer's Disease

ResearchCo Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2020 - 2021

Acoustic based plasmapheresis to prevent antibody-mediated organ transplant

ResearchCo Investigator · Awarded by The Board of Regents of the University of Wisconsin System · 2019 - 2021

An Acoustofluidic Device for Biocompatible Platelet Separation

ResearchPrincipal Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2018 - 2020

Structural dynamics and mechanisms of photoreceptor signaling

ResearchPrincipal Investigator · Awarded by Stony Brook University · 2018 - 2019

Detect autologous transfusion by novel separation and characterization of RBC storage exosomes

ResearchCo Investigator · Awarded by Partnership for Clean Competition · 2018 - 2019

An Acoustofluidic Device for Point-of-Care Sputum Processing and Analysis

ResearchPrincipal Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2017 - 2019

Standing Surface Acoustic Wave Based Cell Sorters for Maintaining Cell Integrity

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2018

Validation of acoustic tweezers for single-cell analyses of purine metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

Single Cell Virology

ResearchPrincipal Investigator · Awarded by Pennsylvania State University · 2016 - 2018

IDBR: Type A: Precise manipulation and patterning of protein nanocrystals using surface acoustic wave technology_BCF

ResearchPrincipal Investigator · Awarded by Stony Brook University · 2016 - 2018

STTR Phase II: Development of Bio-compatible, Bio-safe Cell Sorters

ResearchPrincipal Investigator · Awarded by Ascent Bio-Nano Technologies, Inc. · 2016 - 2017

IDBR: Type A: Precise manipulation and patterning of protein nanocrystals using surface acoustic wave technology

ResearchPrincipal Investigator · Awarded by Stony Brook University · 2016 - 2017

External Relationships


  • Ascent Bio-Nano Technologies, Inc.
  • Department of Biomedical Engineering, Chongqing University, China

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.