Alison Patricia Toth | Scholars@Duke

Alison Patricia Toth
Associate Professor of Orthopaedic Surgery

Dr. Toth specializes in sports medicine with a focus on anterior cruciate ligament (ACL) and multi-ligament knee reconstruction, knee and shoulder arthroscopy, shoulder impingement and instability, rotator cuff tears, articular cartilage healing and repair; meniscus healing and repair; patella dislocation, and cell and molecular biology approaches to the treatment of musculoskeletal injuries.

Current Appointments & Affiliations

Associate Professor of Orthopaedic Surgery, Orthopaedics, Orthopaedics 2021

Contact Information

Box 3970 Med Ctr, Durham, NC 27710
Duke Sports Sciences Institute, 3475 Erwin Rd, Durham, NC 27710
(919) 668-5416

Background
Education, Training, & Certifications
- Orthopaedic Surgery Resident, Surgery, Duke University 1996 - 2000
- General Surgery Resident, Surgery, Duke University 1994 - 1996
- Orthopaedic Research Resident, Surgery, Duke University 1995 - 1996
- M.D., Duke University 1994
Duke Appointment History
- Associate Professor of Orthopaedic Surgery, Orthopaedics, Orthopaedics 2013 - 2020
- Assistant Professor of Orthopaedic Surgery, Orthopaedics, Orthopaedics 2010 - 2013
- Assistant Professor of Surgery, Orthopaedics, Orthopaedics 2001 - 2010
Recognition
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Biomechanical and Biological Predictors of Cartilage Health Following Meniscus Injury awarded by National Institutes of Health 2021 - 2026
- In Vivo Knee Motion and ACL Biomechanics During Dynamic Activities awarded by National Institutes of Health 2019 - 2024
- Chief Leadership Development Program awarded by Piedmont Orthopedic Foundation 2020
- Chief Leadership Development Program awarded by Piedmont Orthopedic Foundation 2019 - 2020
- In Vivo Cartilage Mechanics and Degeneration After ACL Deficiency awarded by National Institutes of Health 2013 - 2017
- Function and Behavior Phenotype of Inflammatory Arthritis in the Rat Knee and TMJ awarded by National Institutes of Health 2009 - 2011
External Relationships
- Vericel Corp
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Flanigan, David C., Seth L. Sherman, Brian Chilelli, Wayne Gersoff, Deryk Jones, Cassandra A. Lee, Alison Toth, Caryn Cramer, Victor Zaporojan, and James Carey. “Consensus on Rehabilitation Guidelines among Orthopedic Surgeons in the United States following Use of Third-Generation Articular Cartilage Repair (MACI) for Treatment of Knee Cartilage Lesions.” Cartilage, October 30, 2020, 1947603520968876. https://doi.org/10.1177/1947603520968876.
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  - Chainani, Abby, Andrew Matson, Masoom Chainani, Axel J. Marchand Colon, Alison P. Toth, Grant E. Garrigues, and Dianne Little. “Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis.” J Shoulder Elbow Surg 29, no. 7 (July 2020): e253–68. https://doi.org/10.1016/j.jse.2019.11.013.
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  - Grimm, N. L., R. Danilkowicz, C. Shortell, and A. P. Toth. “Popliteal Artery Entrapment Syndrome.” Jbjs Rev 8, no. 1 (January 2020): e0035. https://doi.org/10.2106/JBJS.RVW.19.00035.
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  - Bailey, James R., Christopher Kim, Eduard Alentorn-Geli, Donald T. Kirkendall, Leila Ledbetter, Dean C. Taylor, Alison P. Toth, and Grant E. Garrigues. “Rotator Cuff Matrix Augmentation and Interposition: A Systematic Review and Meta-analysis.” Am J Sports Med 47, no. 6 (May 2019): 1496–1506. https://doi.org/10.1177/0363546518774762.
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  - Duchman, Kyle R., Dayne T. Mickelson, Barrett A. Little, Thomas W. Hash, Devin B. Lemmex, Alison P. Toth, and Grant E. Garrigues. “Graft use in the treatment of large and massive rotator cuff tears: an overview of techniques and modes of failure with MRI correlation.” Skeletal Radiol 48, no. 1 (January 2019): 47–55. https://doi.org/10.1007/s00256-018-3015-4.
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  - Lazarides, Alexander L., Eduard Alentorn-Geli, Emily N. Vinson, Thomas W. Hash, Kristian Samuelsson, Alison P. Toth, Claude T. Moorman, William E. Garrett, and Dean C. Taylor. “Advanced Patellar Tendinopathy Is Associated With Increased Rates of Bone-Patellar Tendon-Bone Autograft Failure at Early Follow-up After Anterior Cruciate Ligament Reconstruction.” Orthop J Sports Med 6, no. 11 (November 2018): 2325967118807710. https://doi.org/10.1177/2325967118807710.
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  - Patel, Sunny H., Tejas Nandurkar, Alison P. Toth, and Grant E. Garrigues. “A novel failure mode for biceps tenodesis using fork-tipped interference screws.” J Shoulder Elbow Surg 27, no. 9 (September 2018): e283–87. https://doi.org/10.1016/j.jse.2018.03.033.
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  - Wall, Kevin C., Alison P. Toth, and Grant E. Garrigues. “How to Use a Graft in Irreparable Rotator Cuff Tears: A Literature Review Update of Interposition and Superior Capsule Reconstruction Techniques.” Curr Rev Musculoskelet Med 11, no. 1 (March 2018): 122–30. https://doi.org/10.1007/s12178-018-9466-3.
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  - Alentorn-Geli, Eduard, Joseph J. Stuart, J. H. James Choi, Alison P. Toth, Claude T. Moorman, and Dean C. Taylor. “Posterolateral portal tibial tunnel drilling for posterior cruciate ligament reconstruction: technique and evaluation of safety and tunnel position.” Knee Surg Sports Traumatol Arthrosc 25, no. 8 (August 2017): 2474–80. https://doi.org/10.1007/s00167-015-3958-0.
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  - Neumann, Julie A., Miltiadis H. Zgonis, Kathleen D. Rickert, Kendall E. Bradley, Thomas J. Kremen, Blake R. Boggess, and Alison P. Toth. “Interposition Dermal Matrix Xenografts: A Successful Alternative to Traditional Treatment of Massive Rotator Cuff Tears.” Am J Sports Med 45, no. 6 (May 2017): 1261–68. https://doi.org/10.1177/0363546516683945.
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  - Lederman, Evan S., Alison P. Toth, Gregory P. Nicholson, Robert J. Nowinski, George K. Bal, Gerald R. Williams, and Joseph P. Iannotti. “A prospective, multicenter study to evaluate clinical and radiographic outcomes in primary rotator cuff repair reinforced with a xenograft dermal matrix.” J Shoulder Elbow Surg 25, no. 12 (December 2016): 1961–70. https://doi.org/10.1016/j.jse.2016.02.029.
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  - Alentorn-Geli, Eduard, JH James Choi, Joseph J. Stuart, Alison P. Toth, William E. Garrett, Dean C. Taylor, and Claude T. Moorman. “Inside-Out or Outside-In Suturing Should Not Be Considered the Standard Repair Method for Radial Tears of the Midbody of the Lateral Meniscus: A Systematic Review and Meta-Analysis of Biomechanical Studies.” J Knee Surg 29, no. 7 (October 2016): 604–12. https://doi.org/10.1055/s-0035-1570113.
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  - James Choi, J. H., E. Alentorn-Geli, J. J. Stuart, G. E. Garrigues, and A. P. Toth. “Rotator cuff reconstruction and augmentation using polymer, allograft, and xenograft constructs.” Techniques in Orthopaedics 31, no. 2 (January 1, 2016): 102–7. https://doi.org/10.1097/BTO.0000000000000179.
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  - Alentorn-Geli, Eduard, Joseph J. Stuart, JH James Choi, Alison P. Toth, Claude T. Moorman, and Dean C. Taylor. “Inside-Out Antegrade Tibial Tunnel Drilling Through the Posterolateral Portal Using a Flexible Reamer in Posterior Cruciate Ligament Reconstruction.” Arthrosc Tech 4, no. 5 (October 2015): e537–44. https://doi.org/10.1016/j.eats.2015.05.016.
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  - Kim, Sophia Y., Charles E. Spritzer, Gangadhar M. Utturkar, Alison P. Toth, William E. Garrett, and Louis E. DeFrate. “Knee Kinematics During Noncontact Anterior Cruciate Ligament Injury as Determined From Bone Bruise Location.” Am J Sports Med 43, no. 10 (October 2015): 2515–21. https://doi.org/10.1177/0363546515594446.
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  - Mayer, Stephanie W., Robin M. Queen, Dean Taylor, Claude T. Moorman, Allison P. Toth, William E. Garrett, and Robert J. Butler. “Functional Testing Differences in Anterior Cruciate Ligament Reconstruction Patients Released Versus Not Released to Return to Sport.” Am J Sports Med 43, no. 7 (July 2015): 1648–55. https://doi.org/10.1177/0363546515578249.
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  - Anderson, John A., Dianne Little, Alison P. Toth, Claude T. Moorman, Bradford S. Tucker, Michael G. Ciccotti, and Farshid Guilak. “Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies.” Am J Sports Med 42, no. 9 (September 2014): 2253–61. https://doi.org/10.1177/0363546513508744.
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  - Gupta, Anil K., Kevin Hug, Blake Boggess, Molly Gavigan, and Alison P. Toth. “Massive or 2-tendon rotator cuff tears in active patients with minimal glenohumeral arthritis: clinical and radiographic outcomes of reconstruction using dermal tissue matrix xenograft.” The American Journal of Sports Medicine 41, no. 4 (April 2013): 872–79. https://doi.org/10.1177/0363546512475204.
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  - Stafford, Harry, Blake Boggess, Alison Toth, and David Berkoff. “Anteromedial subtalar dislocation.” Bmj Case Rep 2013 (January 25, 2013). https://doi.org/10.1136/bcr-03-2012-3973.
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  - Magnussen, R. A., D. C. Taylor, A. P. Toth, and W. E. Garrett. “ACL graft failure location differs between allografts and autografts.” Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology 4, no. 1 (June 14, 2012). https://doi.org/10.1186/1758-2555-4-22.
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  - Kraus, V. B., J. Birmingham, T. V. Stabler, S. Feng, D. C. Taylor, C. T. Moorman, W. E. Garrett, and A. P. Toth. “Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254).” Osteoarthritis Cartilage 20, no. 4 (April 2012): 271–78. https://doi.org/10.1016/j.joca.2011.12.009.
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  - Magnussen, Robert A., J Todd R. Lawrence, Ryenn L. West, Alison P. Toth, Dean C. Taylor, and William E. Garrett. “Graft size and patient age are predictors of early revision after anterior cruciate ligament reconstruction with hamstring autograft.” Arthroscopy 28, no. 4 (April 2012): 526–31. https://doi.org/10.1016/j.arthro.2011.11.024.
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  - Gupta, A. K., R. C. Mather, and A. P. Toth. “Reconstruction of massive irreparable rotator cuff tears with dermal xenograft.” Techniques in Shoulder and Elbow Surgery 13, no. 1 (March 1, 2012): 1–5. https://doi.org/10.1097/BTE.0b013e3182400aae.
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  - Adams, S. B., L. A. Setton, E. Kensicki, M. P. Bolognesi, A. P. Toth, and D. L. Nettles. “Global metabolic profiling of human osteoarthritic synovium.” Osteoarthritis Cartilage 20, no. 1 (January 2012): 64–67. https://doi.org/10.1016/j.joca.2011.10.010.
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  - Gupta, Anil K., Kevin Hug, David J. Berkoff, Blake R. Boggess, Molly Gavigan, Paul C. Malley, and Alison P. Toth. “Dermal tissue allograft for the repair of massive irreparable rotator cuff tears.” Am J Sports Med 40, no. 1 (January 2012): 141–47. https://doi.org/10.1177/0363546511422795.
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  - Lawrence, J Todd R., James Birmingham, and Alison P. Toth. “Emerging ideas: prevention of posttraumatic arthritis through interleukin-1 and tumor necrosis factor-alpha inhibition.” Clin Orthop Relat Res 469, no. 12 (December 2011): 3522–26. https://doi.org/10.1007/s11999-010-1699-4.
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  - Toth, A. P., R. F. Warren, F. A. Petrigliano, D. A. Doward, F. A. Cordasco, D. W. Altchek, and S. J. O’Brien. “Thermal Shrinkage for Shoulder Instability.” Hss Journal 7, no. 2 (July 1, 2011): 108–14. https://doi.org/10.1007/s11420-010-9187-7.
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  - Wittstein, Jocelyn R., Robin Queen, Alicia Abbey, Alison Toth, and Claude T. Moorman. “Isokinetic strength, endurance, and subjective outcomes after biceps tenotomy versus tenodesis: a postoperative study.” Am J Sports Med 39, no. 4 (April 2011): 857–65. https://doi.org/10.1177/0363546510387512.
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  - Brown, Christopher, Alison Toth, and Robert Magnussen. “Clinical benefits of intra-articular anakinra for persistent knee effusion.” J Knee Surg 24, no. 1 (March 2011): 61–65. https://doi.org/10.1055/s-0031-1275398.
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  - Wittstein, Jocelyn, Brad Wilson, William E. Garrett, and Alison Toth. “Hamstring graft preparation using a needleless suture loop.” J Surg Orthop Adv 20, no. 2 (2011): 142–44.
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  - Brown, Christopher A., Alison P. Toth, and Bob Magnussen. “Clinical benefits of intra-articular anakinra for arthrofibrosis.” Orthopedics 33, no. 12 (December 1, 2010): 877. https://doi.org/10.3928/01477447-20101021-09.
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  - Garrigues, Grant E., J Mack Aldridge, Alison P. Toth, and Jason E. Stout. “Nontuberculous mycobacterial olecranon bursitis: case reports and literature review.” J Shoulder Elbow Surg 18, no. 2 (March 2009): e1–5. https://doi.org/10.1016/j.jse.2008.07.009.
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  - Rodriguez, William, Emily N. Vinson, Clyde A. Helms, and Alison P. Toth. “MRI appearance of posterior cruciate ligament tears.” Ajr Am J Roentgenol 191, no. 4 (October 2008): 1031. https://doi.org/10.2214/AJR.07.2921.
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  - Koenig, Scott J., Alison P. Toth, and Joseph A. Bosco. “Stress fractures and stress reactions of the diaphyseal femur in collegiate athletes: an analysis of 25 cases.” Am J Orthop (Belle Mead Nj) 37, no. 9 (September 2008): 476–80.
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  - Sohn, David H., and Alison P. Toth. “Meniscus transplantation: current concepts.” J Knee Surg 21, no. 2 (April 2008): 163–72. https://doi.org/10.1055/s-0030-1247813.
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  - Dailiana, Zoe H., Alison P. Toth, Eunice Gunneson, Keith R. Berend, and James R. Urbaniak. “Free vascularized fibular grafting following failed core decompression for femoral head osteonecrosis.” J Arthroplasty 22, no. 5 (August 2007): 679–88. https://doi.org/10.1016/j.arth.2006.12.042.
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  - Queen, Robin M., Terrence T. Crowder, Harvey Johnson, Donald Ozumba, and Alison P. Toth. “Treatment of metatarsal stress fractures: case reports.” Foot Ankle Int 28, no. 4 (April 2007): 506–10. https://doi.org/10.3113/FAI.2007.0506.
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  - Birmingham, James D., Virginia B. Kraus, and Alison P. Toth. “Clinical benefits of intra-articular anakinra (Kineret) for knee signs and symptoms of injury, arthritis, and arthrofibrosis.” Arthritis and Rheumatism 54, no. 12 (December 1, 2006): 4114–4114.
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  - Young, S. D., and A. P. Toth. “Complications of Allograft Use in Anterior Cruciate Ligament Reconstruction.” Operative Techniques in Sports Medicine 14, no. 1 (January 1, 2006): 20–26. https://doi.org/10.1053/j.otsm.2006.02.009.
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  - Larsen, Mitchell W., and Alison Toth. “Examination of posterolateral corner injuries.” J Knee Surg 18, no. 2 (April 2005): 146–50. https://doi.org/10.1055/s-0030-1248173.
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  - Sanders, Alison K., Blake R. Boggess, Scott J. Koenig, and Alison P. Toth. “Medicolegal issues in sports medicine.” Clin Orthop Relat Res, no. 433 (April 2005): 38–49. https://doi.org/10.1097/01.blo.0000159764.03919.33.
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  - Larsen, M. W., and A. Toth. “Examination of posterolateral corner injuries.” The Journal of Knee Surgery 18, no. 2 (2005): 146–50.
  - Koenig, Scott J., Alison P. Toth, Salutario Martinez, James W. Fletcher, and Richard D. Goldner. “Traumatic pseudoaneurysm of the brachial artery caused by an osteochondroma, mimicking biceps rupture in a weightlifter: a case report.” Am J Sports Med 32, no. 4 (June 2004): 1049–53. https://doi.org/10.1177/0363546503258768.
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  - Hervey, Sheleika L., Harriett R. Purves, Ulrich Guller, Alison P. Toth, Thomas P. Vail, and Ricardo Pietrobon. “Provider Volume of Total Knee Arthroplasties and Patient Outcomes in the HCUP-Nationwide Inpatient Sample.” J Bone Joint Surg Am 85, no. 9 (September 2003): 1775–83. https://doi.org/10.2106/00004623-200309000-00017.
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  - Miller, Christine, Nancy Major, and Alison Toth. “Pelvic stress injuries in the athlete: management and prevention.” Sports Med 33, no. 13 (2003): 1003–12. https://doi.org/10.2165/00007256-200333130-00005.
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  - Toth, A. P., and F. A. Cordasco. “Anterior cruciate ligament injuries in the female athlete.” The Journal of Gender Specific Medicine : Jgsm : The Official Journal of the Partnership for Women’S Health at Columbia 4, no. 4 (January 2001): 25–34.
  - Toth, A. P., and M. E. Easley. “Ankle chondral injuries and repair.” Foot Ankle Clin 5, no. 4 (December 2000): 799–840.
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  - Scully, S. P., K. R. Berend, A. Toth, W. N. Qi, Z. Qi, and J. A. Block. “Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.” Clinical Orthopaedics and Related Research, no. 376 (July 2000): 291–303.
  - Scully, S. P., K. R. Berend, A. Toth, W. N. Qi, Z. Qi, and J. A. Block. “Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.” Clin Orthop Relat Res, no. 376 (July 2000): 291–303. https://doi.org/10.1097/00003086-200007000-00038.
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  - Berend, K. R., A. P. Toth, J. M. Harrelson, L. J. Layfield, L. A. Hey, and S. P. Scully. “Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma.” J Bone Joint Surg Am 80, no. 1 (January 1998): 11–17.
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  - Bytomski, J. R., D. Berkoff, and A. Toth. “Intramuscular Pectoralis Major Tear in a Lacrosse Player Performing the Bench Press. A Case Report.” Journal of Athletic Training, n.d.
- Book Sections
  - Johnston, Kenzie, Crystal Higginson, Heather Saffel, Allison Toth, Kendall Bradley, and Moreno Anna. “The Female Basketball Player (In preparation).” In Basketball Sports Medicine and Science. Springer, 2020.
  - Toth, A. P., M. E. Easley, and S. D. Sides. “Osteochondral Lesions of the Talus,” 2004.
  - Toth, A. P., and R. F. Warren. “Medial Side Injuries of the Knee: Acute and Chronic Management,” 801–22. Philadelphia, Lippincott, Williams, and Wilkins, 2003.
- Digital Publications
  - Toth, A. P., and R. F. Warren. “Pectoralis Ruptures,” 2002.
Scholarly, Clinical, & Service Activities
Presentations & Appearances

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Education, Training, & Certifications

Duke Appointment History

Awards & Honors

Subject Headings

Selected Grants

External Relationships

Selected Publications

Academic Articles

Book Sections

Digital Publications

Presentations & Appearances